Aliases & Classifications for Neuritis

MalaCards integrated aliases for Neuritis:

Name: Neuritis 12 55 44 15 73
Peripheral Neuritis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1803
MeSH 44 D009443
NCIt 50 C116381
SNOMED-CT 68 84299009
UMLS 73 C0027813

Summaries for Neuritis

MalaCards based summary : Neuritis, also known as peripheral neuritis, is related to optic neuritis and autoimmune optic neuritis, and has symptoms including sciatica and neuralgia. An important gene associated with Neuritis is PMP2 (Peripheral Myelin Protein 2), and among its related pathways/superpathways are Cytokine Signaling in Immune system and PAK Pathway. The drugs Prednisone and Mycophenolic acid have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and eye, and related phenotypes are hematopoietic system and behavior/neurological

Wikipedia : 76 Neuritis (/nj�?�?�?raɪtɪs/) is inflammation of a nerve or the general inflammation of the peripheral... more...

Related Diseases for Neuritis

Diseases related to Neuritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 511)
# Related Disease Score Top Affiliating Genes
1 optic neuritis 33.8 AQP4 MAG MBP MOG MPZ TNF
2 autoimmune optic neuritis 33.5 AQP4 MBP MOG
3 neuromyelitis optica 32.7 AQP4 MBP MOG
4 optic nerve disease 32.3 AQP4 MBP MOG
5 amyotrophic neuralgia 32.1 PMP22 SEPT9
6 myelitis 30.5 AQP4 MBP MOG TNF
7 transverse myelitis 30.4 AQP4 MBP TNF
8 allergic encephalomyelitis 30.3 MBP MOG
9 acquired immunodeficiency syndrome 30.0 IFNG IL1B TNF
10 acute disseminated encephalomyelitis 30.0 AQP4 IL1B MBP MOG MPZ
11 miller fisher syndrome 30.0 MAG TNF
12 meningitis 30.0 CCL2 IFNG IL1B TNF
13 arthritis 29.9 CCL2 IFNG IL1B TNF
14 guillain-barre syndrome 29.8 MBP MPZ PMP2 PMP22 TNF
15 polyneuropathy 29.8 MAG MBP MPZ PMP22
16 ulcerative colitis 29.8 IFNG IL1B TNF
17 chronic inflammatory demyelinating polyradiculoneuropathy 29.8 IFNG MPZ PMP22
18 aseptic meningitis 29.7 IFNG IL1B TNF
19 leprosy 3 29.7 IFNG IL4 TNF
20 osteomyelitis 29.7 IFNG IL1B TNF
21 rubella 29.6 IL4 MOG TNF
22 uveitis 29.6 CCL2 CXCL10 IFNG IL4 TNF
23 encephalitis 29.5 AQP4 CCL2 CCL5 CXCL10 IL1B MOG
24 crohn's colitis 29.5 IFNG IL1B TNF
25 typhoid fever 29.5 IFNG IL1B TNF
26 lymphadenitis 29.4 IFNG IL1B TNF
27 polyradiculoneuropathy 29.4 IFNG MAG MBP MPZ PMP2 PMP22
28 q fever 29.4 IFNG IL1B IL4 TNF
29 sensory peripheral neuropathy 29.4 MAG MPZ PMP22
30 human immunodeficiency virus infectious disease 29.4 CCL5 IFNG TNF
31 poliomyelitis 29.3 IFNG IL4 TNF
32 pulmonary tuberculosis 29.3 IFNG IL4 TNF
33 keratoconjunctivitis 29.3 IFNG IL4 TNF
34 chlamydia 29.3 IFNG IL1B IL4 TNF
35 chikungunya 29.3 CCL2 CCL5 IL1B TNF
36 colitis 29.3 IFNG IL1B IL4 TNF
37 brucellosis 29.3 IFNG IL4 TNF
38 schistosomiasis 29.2 IFNG IL4 TNF
39 charcot-marie-tooth disease 29.2 MAG MBP MPZ PMP2 PMP22
40 myasthenia gravis 29.2 IFNG IL4 MBP TNF
41 otitis media 29.1 IL1B IL4 TNF
42 relapsing-remitting multiple sclerosis 29.1 AQP4 CCL5 IFNG IL4 MBP MOG
43 toxoplasmosis 29.1 IFNG IL1B IL4 TNF
44 cytomegalovirus infection 29.0 CCL2 CCL5 IL1B TNF
45 scleritis 29.0 CCL2 IFNG IL4 TNF
46 pneumonia 29.0 CCL2 CCL5 IL1B TNF
47 viral infectious disease 29.0 CCL5 CXCL10 IFNG IL1B IL4 TNF
48 systemic lupus erythematosus 29.0 CCL2 CCL5 CXCL10 IFNG IL1B IL4
49 rheumatoid arthritis 29.0 CCL2 CCL5 IFNG IL1B IL4 TNF
50 multiple sclerosis 29.0 TNF MPZ MOG MBP MAG IL4

Graphical network of the top 20 diseases related to Neuritis:



Diseases related to Neuritis

Symptoms & Phenotypes for Neuritis

UMLS symptoms related to Neuritis:


sciatica, neuralgia

MGI Mouse Phenotypes related to Neuritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.1 AQP4 CCL5 CXCL10 IFNG IL1B IL4
2 behavior/neurological MP:0005386 10.06 AQP4 IFNG MAG MBP MOG MPZ
3 cellular MP:0005384 10.02 CXCL10 IFNG IL4 MBP MOG MPZ
4 homeostasis/metabolism MP:0005376 10 AQP4 CXCL10 IFNG IL1B IL4 MAG
5 immune system MP:0005387 9.97 AQP4 CCL2 CCL5 CXCL10 IFNG IL1B
6 nervous system MP:0003631 9.73 AQP4 CXCL10 IFNG IL1B IL4 MAG
7 vision/eye MP:0005391 9.17 AQP4 IFNG IL4 MBP MOG PMP22

Drugs & Therapeutics for Neuritis

Drugs for Neuritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 254)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 53-03-2 5865
2
Mycophenolic acid Approved Phase 4 24280-93-1 446541
3
Mitoxantrone Approved, Investigational Phase 4 65271-80-9 4212
4
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 302-25-0
5
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-24-8 5755
6
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 2921-57-5
7
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 83-43-2 6741
8
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 1,Phase 2,Early Phase 1,Not Applicable 1177-87-3
9
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 1,Phase 2,Early Phase 1,Not Applicable 50-02-2 5743
10
Bevacizumab Approved, Investigational Phase 4,Phase 1,Phase 2,Early Phase 1 216974-75-3
11
Interferon beta-1a Approved, Investigational Phase 4,Phase 3 145258-61-3 6438354
12
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
13
leucovorin Approved Phase 4 58-05-9 6006 143
14
Rifampicin Approved Phase 4 13292-46-1 5458213 5381226
15
Dapsone Approved, Investigational Phase 4 80-08-0 2955
16
Clofazimine Approved, Investigational Phase 4 2030-63-9 2794
17
Mannitol Approved, Investigational Phase 4 69-65-8 453 6251
18
Prilocaine Approved Phase 4 721-50-6 4906
19
Racepinephrine Approved Phase 4 329-65-7 838
20
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
21
Nitric Oxide Approved Phase 4 10102-43-9 145068
22
Acetylcholine Approved Phase 4 51-84-3 187
23
4-Aminopyridine Approved Phase 4,Phase 2,Phase 3 504-24-5 1727
24
Levodopa Approved Phase 4 59-92-7 6047
25
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
26
Carbidopa Approved Phase 4 28860-95-9 34359 38101
27
Interferon beta-1b Approved Phase 4,Phase 2,Phase 3 145155-23-3
28
Idebenone Approved, Investigational Phase 4,Phase 3,Phase 2 58186-27-9
29
Tadalafil Approved, Investigational Phase 4 171596-29-5 110635
30
Methotrexate Approved Phase 4 59-05-2, 1959-05-2 126941
31
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
32
Ofloxacin Approved Phase 4 82419-36-1 4583
33
Azithromycin Approved Phase 4 83905-01-5 55185 447043
34
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
35
Clarithromycin Approved Phase 4 81103-11-9 84029
36
Linezolid Approved, Investigational Phase 4 165800-03-3 441401
37
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 1 59-30-3 6037
38
Choline Approved, Nutraceutical Phase 4,Not Applicable 62-49-7 305
39
Prednisolone hemisuccinate Experimental Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 2920-86-7
40 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
41 Immunologic Factors Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
42 Adjuvants, Immunologic Phase 4,Phase 3,Phase 2,Not Applicable
43
Glatiramer Acetate Phase 4,Phase 3,Phase 2 147245-92-9 3081884
44 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1
45 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
46 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
47 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
48 Antibiotics, Antitubercular Phase 4
49 Anti-Bacterial Agents Phase 4,Phase 2
50 Anti-Infective Agents Phase 4,Phase 2,Phase 3

Interventional clinical trials:

(show top 50) (show all 234)
# Name Status NCT ID Phase Drugs
1 Optical Coherence Tomography: Glatiramer in Clinically Isolated Syndrome or Early Relapsing Remitting Multiple Sclerosis (MS) Unknown status NCT00910598 Phase 4 glatiramer acetate
2 Mycophenolate Mofetil Treatment With Neuromyelitis Optica Spectrum Disorders in Chinese Patients Unknown status NCT02809079 Phase 4 Mycophenolate mofetil;Prednisone
3 Efficacy and Safety of Mitoxantrone in Patients With Refractory Neuromyelitis Optica and Spectrum Disorders Unknown status NCT02021825 Phase 4 Mitoxantrone
4 Effect of High-Dose Prednisolone (Solu Dacortin®) Treatment on Choroidal and Optic Nerve Head Blood Flow in Humans Completed NCT00312325 Phase 4 Prednisolone
5 Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis Completed NCT00179478 Phase 4 interferon beta 1a 30 ug IM once weekly
6 Dexamethasone & Bupivacaine vs Bupivacaine Alone in Combined Femoral and Sciatic Nerve Block for Perioperative Analgesia in Patients Undergoing Lower Limb Surgeries Completed NCT02576782 Phase 4 Perineural Dexamethasone and bupivacaine;Systemic Dexamethasone plus perineural bupivacaine;intravenous saline plus perineural bupivacaine
7 Oral Corticotherapy in Megadoses to Treat Multiple Sclerosis During Relapse Completed NCT00753792 Phase 4 methylprednisolone;methylprednisolone;Placebo
8 Uniform Multidrug Therapy Regimen for Leprosy Patients Completed NCT00669643 Phase 4 PB 6 doses - Rifampicin and Dapsone;PB 6 doses - Rifampicin, Clofazimine and Dapsone;MB 12 doses - Rifampicin, Clofazimine and Dapsone;MB 6 doses - Rifampicin, Clofazimine and Dapsone
9 Use of Bevacizumab in Trabeculectomy Surgery Completed NCT01166594 Phase 4 Bevacizumab;Control
10 Evaluation of Ureteral Patency in the Post-indigo Carmine Era Completed NCT02677623 Phase 4 Pyridium;Sodium Fluorescein;Mannitol
11 Study to Evaluate the Efficacy of Botulinum Toxin Serotype A Injections for Cervicobrachial Myofascial Syndrome Completed NCT00241215 Phase 4 Botulinum toxin serotype A
12 A New Medicine to Treat Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) Completed NCT01975324 Phase 4 dalfampridine;Placebo
13 Effect of Levodopa-Carbidopa on Visual Function in Patients With Recent-Onset Nonarteritic Anterior Ischemic Optic Neuropathy Completed NCT00432393 Phase 4 levodopa-carbidopa
14 A Study of Fluzone® High-Dose Vaccine Compared With Fluzone® Vaccine In Elderly Adults Completed NCT01427309 Phase 4
15 Citicoline Effect on Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) Completed NCT03046693 Phase 4 Group A Citicoline 1000 mg oral tablet;Group B placebo oral tablet
16 Neural Conduction Along the Visual Pathways After Oral Treatment With Citicoline in Patients With Optic Nerve Diseases Completed NCT00404729 Phase 4 Cytidine-5’-diphosphocholine (Citicoline)
17 Follow-up Study After 11 Years of Patients Who Were Included in the BENEFIT Trial (304747) With a First Demyelinating Event Suggestive of Multiple Sclerosis Completed NCT01795872 Phase 4
18 A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic’s Disease) Completed NCT00304291 Phase 4 Mitoxantrone
19 Post-lesion Administration of Dexamethasone to Prevent the Development of Neuritis After Radiofrequency Ablation Recruiting NCT03247413 Phase 4 Dexamethasone 4 mg/ml;Normal saline
20 A Trial of Neuroprotection With ACTH in Acute Optic Neuritis Recruiting NCT01838174 Phase 4 ACTHAR Gel (ACTH);IV methylprednisolone (steroids)
21 Study to Assess the Efficacy and Safety of Raxone in LHON Patients Recruiting NCT02774005 Phase 4 Idebenone
22 Linezolid for Treatment of Nontuberculous Mycobacterial Diseases Not yet recruiting NCT03220074 Phase 4 Oral Tablet
23 Modeling and Treating the Pathophysiology of Demyelination in Multiple Sclerosis Terminated NCT00854750 Phase 4 ACTHAR;ACTHAR;ACTHAR;ACTHAR
24 PDE5 Inhibitor Use and Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) Terminated NCT00867815 Phase 4 Diagnostic procedures
25 Induction Therapy With a Single High Dose Bolus of Intravenous Methotrexate With Leucovorin Rescue, Prior to Initiation of AVONEX® Treatment, in Patients Presenting With a First Acute Demyelinating Event. Withdrawn NCT00037115 Phase 4 interferon beta 1a;methotrexate;methylprednisolone
26 A Proof-of-Concept Study to Correlate Retinal Nerve Fiber Layer Changes in Patients With Multiple Sclerosis Treated With Natalizumab or Interferon Beta 1-a Withdrawn NCT00771043 Phase 4 TYSABRI and AVONEX
27 Simvastatin Treatment of Patients With Acute Optic Neuritis Unknown status NCT00261326 Phase 3 simvastatin;placebo
28 Optic Neuritis Treatment Trial (ONTT) Unknown status NCT00000146 Phase 3 Methylprednisolone;Prednisone
29 Outcomes of Steroid and Oxygen Therapy Versus Placebo Therapy in Non-arteritic Anterior Ischemic Optic Neuropathy Unknown status NCT02439866 Phase 3 placebo;Intravenous methylprednisolone;normobaric oxygen with face mask
30 Retrobulbar Triamcinolone Acetonide Injection in the Treatment of NA-AION Unknown status NCT02329288 Phase 3 Triamcinolone Acetonide;placebo
31 Phase III Randomized, Double-Blind, Sham-Controlled Study of Plasma Exchange for Acute Severe Attacks of Inflammatory Demyelinating Disease Refractory to Intravenous Methylprednisolone Unknown status NCT00004645 Phase 3
32 The Efficacy of Steroid Therapy in Vestibular Neuritis Completed NCT02098330 Phase 3 Ginkgo biloba & Methylprednisolone;Ginkgo biloba
33 Ampyra for Optic Neuritis in MS Completed NCT01337986 Phase 2, Phase 3 Dalfampridine/Placebo;Placebo/Dalfampridine
34 A Randomized, Double-blind, Placebo-controlled, Multicenter Study of the Effects of Glatiramer Acetate (GA) on the Retinal Nerve Fiber Layer (RNFL) and Visual Function in Patients With a First Episode of Acute Optic Neuritis (AON). (Octagon) Completed NCT00856635 Phase 3 Glatiramer Acetate;placebo
35 Optic Neuritis Recovery After Oral or IV Corticosteroids Completed NCT01524250 Phase 2, Phase 3 corticosteroids;corticosteroids
36 Intravenous Immunoglobulin Therapy in Optic Neuritis Completed NCT00000117 Phase 3 Immunoglobulin
37 Additional 6-Month Safety Follow-up After Completion of Precursor Study 880801 Completed NCT01604746 Phase 3
38 Study of the Effectiveness of Intravenous Immune Globulin (10%) for the Treatment of Multifocal Motor Neuropathy Completed NCT00666263 Phase 3
39 Hypoalgesic Effect of Neural Mobilization Versus Ibuprofen Pharmacologic Treatment Completed NCT02593721 Phase 2, Phase 3 Ibuprofen
40 Phase III Clinical Trial of NPB-01maintenance Therapy in Patients With Multifocal Motor Neuropathy. Completed NCT01827072 Phase 3 NPB-01
41 Paraorbital-Occipital Electric Stimulation in Patients With Optic Neuropathy (BCT_optnerve) Completed NCT01282827 Phase 2, Phase 3
42 A Double Blind Trial To Evaluate The Safety And Efficacy Of Eculizumab In Relapsing NMO Patients (PREVENT Study) Completed NCT01892345 Phase 3 Eculizumab
43 Ischemic Optic Neuropathy Decompression Trial (IONDT) Completed NCT00000127 Phase 3
44 Study to Evaluate Immunogenicity of the Hepatitis B Antigen of the GSK Biologicals' Candidate Malaria Vaccine (257049) Completed NCT01345240 Phase 3
45 A Randomized, Double-blind, Placebo-controlled Trial of Curcumin in Leber's Hereditary Optic Neuropathy (LHON) Completed NCT00528151 Phase 3 curcumin
46 Comparison of Clinical Effects of Azathioprine and Rituximab NMO-SD Patients Completed NCT03002038 Phase 2, Phase 3 Azathioprine;Rituximab
47 Bortezomib in Intrahepatic Cholangiocellular Carcinoma Recruiting NCT03345303 Phase 3 Bortezomib
48 Efficacy & Safety of RPh201 Treatment in Patients With Previous Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) Recruiting NCT03547206 Phase 3 RPh201
49 Traumatic Optic Neuropathy Treatment Trial 2 Recruiting NCT03308448 Phase 3 Recombinant human erythropoietin
50 Efficacy and Safety Study of Bilateral Intravitreal Injection of GS010 for the Treatment of Vision Loss up to 1 Year From Onset in LHON Due to the ND4 Mutation Recruiting NCT03293524 Phase 3 Placebo

Search NIH Clinical Center for Neuritis

Cochrane evidence based reviews: neuritis

Genetic Tests for Neuritis

Anatomical Context for Neuritis

MalaCards organs/tissues related to Neuritis:

41
Brain, Testes, Eye, T Cells, Bone, Spinal Cord, Pituitary

Publications for Neuritis

Articles related to Neuritis:

(show top 50) (show all 1928)
# Title Authors Year
1
Malignant optic glioma masked by suspected optic neuritis and central retinal vein occlusion. ( 30450148 )
2019
2
More than meets the eye: Point-of-care ultrasound diagnosis of acute optic neuritis in the emergency department. ( 30314903 )
2019
3
Valuable Insights Into Visual Neuroplasticity After Optic Neuritis. ( 29297048 )
2018
4
Early Nodal and Paranodal Disruption in Autoimmune Optic Neuritis. ( 29444299 )
2018
5
Clinical value of 4-hour delayed gadolinium-Enhanced 3D FLAIR MR Images in Acute Vestibular Neuritis. ( 29330961 )
2018
6
Vestibular paroxysmia in vestibular neuritis: A case report. ( 29910862 )
2018
7
Why Therapeutic Compliance in Optic Neuritis Deserves to Be More Than Just a Footnote: Response. ( 29923869 )
2018
8
Binocular cyclotorsion in superior vestibular neuritis. ( 29967552 )
2018
9
Roles of macrophage migration inhibitory factor in Guillain-BarrAc syndrome and experimental autoimmune neuritis: beneficial or harmful? ( 29856236 )
2018
10
Anatomical Wiring and Functional Networking Changes in the Visual System Following Optic Neuritis. ( 29297053 )
2018
11
Decitabine induces regulatory T cells, inhibits the production of IFN-gamma and IL-17 and exerts preventive and therapeutic efficacy in rodent experimental autoimmune neuritis. ( 29957387 )
2018
12
The extent of vestibular impairment is important in recovery of canal paresis of patients with vestibular neuritis. ( 29866420 )
2018
13
Paediatric ADEM followed by optic neuritis: disease course, treatment response and outcome. ( 29443442 )
2018
14
Progressive inner nuclear layer dysfunction in non-optic neuritis eyes in MS. ( 29259999 )
2018
15
Association of Optic Neuritis with <i>CYP4F2</i> Gene Single Nucleotide Polymorphism and IL-17A Concentration. ( 29736281 )
2018
16
Structural and visual functional deficits in a rat model of neuromyelitis optica spectrum disorders related optic neuritis. ( 29913164 )
2018
17
Guillain-BarrAc syndrome and optic neuritis after Mycoplasma pneumoniae infection. ( 29429558 )
2018
18
Hypertrophic neuritis causing tetraparesis in a cat. ( 29925717 )
2018
19
Active Leprosy Neuritis Detected on FDG PET/CT. ( 29261639 )
2018
20
Vestibular neuritis selectively involving posterior canal and utricle. ( 29938335 )
2018
21
Clinical features of demyelinating optic neuritis with seropositive myelin oligodendrocyte glycoprotein antibody in Chinese patients. ( 29363529 )
2018
22
Short-term effect of additional apheresis on visual acuity changes in patients with steroid-resistant optic neuritis in neuromyelitis optica spectrum disorders. ( 29802557 )
2018
23
MD1003 (High-Dose Pharmaceutical-Grade Biotin) for the Treatment of Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Study. ( 29808469 )
2018
24
Brachial plexitis or neuritis? MRI features of lesion distribution in Parsonage-Turner syndrome. ( 29461642 )
2018
25
Beneficial or Harmful Role of Macrophages in Guillain-BarrAc Syndrome and Experimental Autoimmune Neuritis. ( 29853789 )
2018
26
Clinical presentation of optic neuritis with autoantibodies anti-myelin oligodendrocyte glycoprotein. ( 29972029 )
2018
27
High resolution retinal scanning reveals regional structural differences between MS and NMOSD optic neuritis regardless of antibody status. ( 29249380 )
2018
28
Early Diagnosis of Recurrent Optic Neuritis Using Contrast-Enhanced T2 Fluid-attenuated Inversion Recovery Imaging: a Case Report. ( 29976284 )
2018
29
The unfaithful neuritis. ( 29859200 )
2018
30
Neuromyelitis Optica: Review and Utility of Testing Aquaporin-4 Antibody in Typical Optic Neuritis. ( 29766684 )
2018
31
Why Therapeutic Compliance in Optic Neuritis Deserves to be More Than Just a Footnote. ( 29901490 )
2018
32
Recurrent idiopathic neuroretinitis as a spectrum of atypical optic neuritis: a case report and literature review. ( 29538599 )
2018
33
Possible Combined Central and Peripheral Demyelination Presenting as Optic Neuritis, Cervical Myelitis, and Demyelinating Polyneuropathy with Marked Nerve Hypertrophy. ( 29540658 )
2018
34
Typical optic neuritis? ( 29941727 )
2018
35
Relapsing acute disseminated encephalomyelitis followed by optic neuritis in children; a clinical entity associated with anti-MOG antibody. ( 29790244 )
2018
36
Differentiating Neuromyelitis Optica-Related and Multiple Sclerosis-Related Acute Optic Neuritis Using Conventional Magnetic Resonance Imaging Combined With Readout-Segmented Echo-Planar Diffusion-Weighted Imaging. ( 29787495 )
2018
37
Erratum: Progressive inner nuclear layer dysfunction in non-optic neuritis eyes in MS. ( 29417957 )
2018
38
MOG-IgG-Associated Optic Neuritis, Encephalitis, and Myelitis: Lessons Learned From Neuromyelitis Optica Spectrum Disorder. ( 29670575 )
2018
39
Retinal nerve fiber layer and ganglion cell layer changes on optical coherence tomography in early multiple sclerosis and optic neuritis cases. ( 29283135 )
2018
40
Advanced diffusion-weighted imaging in patients with optic neuritis deficit - value of reduced field of view DWI and readout-segmented DWI. ( 29417865 )
2018
41
Recurrent Optic Neuritis as the Initial Symptom in Demyelinating Diseases. ( 29856159 )
2018
42
Rituximab was effective for acute disseminated encephalomyelitis followed by recurrent optic neuritis with anti-myelin oligodendrocyte glycoprotein antibodies. ( 29661590 )
2018
43
Baseline Brain Activity Changes in Patients With Single and Relapsing Optic Neuritis. ( 29731712 )
2018
44
Time to steroid treatment in severe acute optic neuritis. ( 29931830 )
2018
45
Macular choroidal thickness and peripapillary retinal nerve fiber layer thickness in normal adults and patients with optic atrophy due to acute idiopathic demyelinating optic neuritis. ( 29856811 )
2018
46
Incidence and Causes of Overdiagnosis of Optic Neuritis. ( 29222573 )
2018
47
Diagnosis and treatment of anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis. ( 29445944 )
2018
48
Clinical Characteristics of Pediatric Optic Neuritis With Myelin Oligodendrocyte Glycoprotein Seropositive: A Cohort Study. ( 29778487 )
2018
49
Exploring experimental autoimmune optic neuritis using multimodal imaging. ( 29627590 )
2018
50
Selective Vulnerability of αOFF Retinal Ganglion Cells during Onset of Autoimmune Optic Neuritis. ( 30075244 )
2018

Variations for Neuritis

Expression for Neuritis

Search GEO for disease gene expression data for Neuritis.

Pathways for Neuritis

Pathways related to Neuritis according to GeneCards Suite gene sharing:

(show all 50)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.3 CCL2 CCL5 CXCL10 IFNG IL1B IL4
2
Show member pathways
13.23 CCL2 CCL5 CXCL10 IL1B IL4 TNF
3
Show member pathways
12.96 CCL2 CCL5 CXCL10 IFNG IL1B TNF
4
Show member pathways
12.76 CCL2 CCL5 CXCL10 IFNG IL1B IL4
5
Show member pathways
12.72 CCL5 CXCL10 IFNG IL1B TNF
6
Show member pathways
12.54 IFNG IL1B IL4 TNF
7
Show member pathways
12.53 CCL2 IFNG IL1B TNF
8
Show member pathways
12.38 IFNG IL1B IL4 TNF
9 12.38 CCL2 CCL5 CXCL10 IFNG IL1B IL4
10
Show member pathways
12.27 CCL2 CCL5 IFNG IL1B IL4 TNF
11
Show member pathways
12.24 CCL2 CXCL10 IFNG IL1B IL4 TNF
12
Show member pathways
12.22 IFNG IL1B IL4 TNF
13
Show member pathways
12.21 IFNG IL1B IL4 TNF
14
Show member pathways
12.18 CXCL10 IFNG IL1B IL4 TNF
15 12.06 CCL2 IFNG IL1B TNF
16
Show member pathways
12.04 CCL2 CCL5 IFNG IL1B IL4
17
Show member pathways
12.01 IFNG IL1B IL4 TNF
18
Show member pathways
12 IFNG IL1B TNF
19 11.99 IFNG IL1B TNF
20 11.96 CCL2 IL1B IL4 TNF
21 11.95 CCL2 CCL5 CXCL10 IL1B TNF
22
Show member pathways
11.94 CCL2 CCL5 CXCL10
23 11.94 IFNG IL4 TNF
24
Show member pathways
11.92 IFNG IL1B IL4
25 11.87 MBP MPZ PMP22
26 11.85 CCL2 IL1B TNF
27 11.84 IL1B IL4 TNF
28 11.83 IFNG IL1B TNF
29 11.79 IFNG IL1B IL4 TNF
30 11.76 CCL2 CCL5 IFNG IL1B TNF
31
Show member pathways
11.73 IFNG IL4 TNF
32 11.71 IFNG IL1B TNF
33
Show member pathways
11.63 IFNG IL1B TNF
34 11.55 CCL2 IFNG IL1B TNF
35 11.53 CCL2 IFNG IL1B TNF
36 11.5 IFNG IL1B TNF
37 11.47 IFNG IL1B TNF
38 11.45 CCL2 CCL5 IL1B IL4 TNF
39 11.37 CXCL10 IFNG IL1B
40 11.36 AQP4 CCL2 CXCL10 IFNG IL1B IL4
41 11.35 CCL2 CCL5 CXCL10 IFNG IL1B IL4
42 11.34 IFNG IL1B TNF
43 11.32 CCL2 CCL5 CXCL10 IL1B IL4 TNF
44 11.3 IFNG IL1B IL4 TNF
45 11.24 IFNG IL1B IL4 TNF
46 11.17 CCL2 IFNG IL1B
47 11.08 CCL2 CCL5 CXCL10 IL1B IL4 TNF
48 10.98 CCL2 CCL5 CXCL10 IL1B IL4 SEPT9
49 10.96 CCL2 IL1B TNF
50 10.57 MAG MBP

GO Terms for Neuritis

Cellular components related to Neuritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.7 CCL2 CCL5 CXCL10 IFNG IL1B IL4
2 external side of plasma membrane GO:0009897 9.56 AQP4 CXCL10 MOG TNF
3 myelin sheath GO:0043209 9.26 MAG MBP MPZ PMP2
4 compact myelin GO:0043218 8.8 MAG MBP PMP22

Biological processes related to Neuritis according to GeneCards Suite gene sharing:

(show all 41)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.94 CCL2 CCL5 IL1B TNF
2 inflammatory response GO:0006954 9.93 CCL2 CCL5 CXCL10 IL1B TNF
3 MAPK cascade GO:0000165 9.88 CCL2 CCL5 IL1B MBP TNF
4 cellular response to lipopolysaccharide GO:0071222 9.86 CCL2 CXCL10 IL1B TNF
5 cytokine-mediated signaling pathway GO:0019221 9.85 CCL2 CCL5 CXCL10 IL1B IL4 TNF
6 cellular response to interferon-gamma GO:0071346 9.83 AQP4 CCL2 CCL5
7 cell chemotaxis GO:0060326 9.82 CCL2 CCL5 CXCL10
8 response to virus GO:0009615 9.81 CCL5 CXCL10 IFNG TNF
9 chemokine-mediated signaling pathway GO:0070098 9.8 CCL2 CCL5 CXCL10
10 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.8 CCL5 IFNG IL4
11 neutrophil chemotaxis GO:0030593 9.8 CCL2 CCL5 CXCL10 IL1B
12 positive regulation of T cell proliferation GO:0042102 9.79 CCL5 IL1B IL4
13 humoral immune response GO:0006959 9.77 CCL2 IFNG TNF
14 myelination GO:0042552 9.76 MBP MPZ PMP22
15 cellular response to organic cyclic compound GO:0071407 9.73 CCL2 CCL5 IL1B TNF
16 positive regulation of nitric oxide biosynthetic process GO:0045429 9.72 IFNG IL1B TNF
17 regulation of insulin secretion GO:0050796 9.71 CCL5 IFNG IL1B TNF
18 regulation of signaling receptor activity GO:0010469 9.7 CCL2 CCL5 CXCL10 IFNG IL1B IL4
19 positive regulation of osteoclast differentiation GO:0045672 9.68 IFNG TNF
20 response to vitamin D GO:0033280 9.68 CXCL10 IL1B
21 positive regulation of monocyte chemotaxis GO:0090026 9.68 CCL5 CXCL10
22 negative regulation of lipid catabolic process GO:0050995 9.68 IL1B TNF
23 positive regulation of glial cell proliferation GO:0060252 9.67 IL1B TNF
24 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.67 IL1B TNF
25 positive regulation of T cell migration GO:2000406 9.67 CCL5 CXCL10
26 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.66 IL1B TNF
27 macrophage chemotaxis GO:0048246 9.66 CCL2 CCL5
28 cell-cell adhesion via plasma-membrane adhesion molecules GO:0098742 9.65 MAG MPZ
29 positive regulation of astrocyte differentiation GO:0048711 9.65 IL1B MAG
30 positive regulation of chemokine biosynthetic process GO:0045080 9.63 IL1B TNF
31 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.63 IFNG IL1B TNF
32 regulation of establishment of endothelial barrier GO:1903140 9.62 IL1B TNF
33 protein kinase B signaling GO:0043491 9.62 CCL2 CCL5 IL1B TNF
34 positive regulation of neuroinflammatory response GO:0150078 9.61 IL1B TNF
35 positive regulation of fever generation GO:0031622 9.59 IL1B TNF
36 chronic inflammatory response to antigenic stimulus GO:0002439 9.58 IL1B TNF
37 sequestering of triglyceride GO:0030730 9.57 IL1B TNF
38 lipopolysaccharide-mediated signaling pathway GO:0031663 9.56 CCL2 CCL5 IL1B TNF
39 positive regulation of vitamin D biosynthetic process GO:0060557 9.52 IFNG TNF
40 immune response GO:0006955 9.23 CCL2 CCL5 CXCL10 IFNG IL1B IL4
41 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.13 IFNG IL1B TNF

Molecular functions related to Neuritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.17 CCL2 CCL5 CXCL10 IFNG IL1B IL4
2 chemokine activity GO:0008009 9.13 CCL2 CCL5 CXCL10

Sources for Neuritis

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