Neuroaspergillosis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Neuroaspergillosis

MalaCards integrated aliases for Neuroaspergillosis:

Name: Neuroaspergillosis ¹² ¹⁵ ¹⁷ ⁷¹

Classifications:

MalaCards categories:
Global: Infectious diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:13565

MeSH ⁴³ D020953 {http

EFO ¹⁷ EFO_0007393

UMLS ⁷¹ C0752342

Sources

Summaries for Neuroaspergillosis

Disease Ontology : ¹² An aspergillosis that involves fungal infection of the central nervous system in immunocompromised patients caused by Aspergillus, presenting as a space-occupying lesion.

MalaCards based summary : Neuroaspergillosis is related to aspergillosis and myeloma, multiple. An important gene associated with Neuroaspergillosis is DYRK3 (Dual Specificity Tyrosine Phosphorylation Regulated Kinase 3). Affiliated tissues include brain and liver.

Sources

Related Diseases for Neuroaspergillosis

Diseases related to Neuroaspergillosis via text searches within MalaCards or GeneCards Suite gene sharing:

#	Related Disease	Score	Top Affiliating Genes
1	aspergillosis	10.4
2	myeloma, multiple	10.2
3	yemenite deaf-blind hypopigmentation syndrome	10.2
4	leukemia, acute lymphoblastic	10.2
5	chronic granulomatous disease	10.2
6	fungal meningitis	9.3	DYRK3 CYP51A1

Graphical network of the top 20 diseases related to Neuroaspergillosis:

Sources

Symptoms & Phenotypes for Neuroaspergillosis

Sources

Drugs & Therapeutics for Neuroaspergillosis

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	A Prospective, Randomized Trial Comparing The Safety, Tolerability, And Efficacy Of Voriconazole And Anidulafungin In Combination To That Of Voriconazole Alone When Used For Primary Therapy Of Invasive Aspergillosis in Pediatric Subjects Aged 2 to 17 Years	Withdrawn	NCT01188759	Phase 3	Voriconazole;Anidulafungin;Voriconazole

Search NIH Clinical Center for Neuroaspergillosis

Sources

Genetic Tests for Neuroaspergillosis

Sources

Anatomical Context for Neuroaspergillosis

MalaCards organs/tissues related to Neuroaspergillosis:

⁴⁰

Brain, Liver

Sources

Publications for Neuroaspergillosis

Articles related to Neuroaspergillosis:

#	Title	Authors	PMID	Year
1	Neuroaspergillosis as the Presenting Sign of a Chronic Granulomatous Disease. ⁶¹	Salomone G...Pratico AD	31570298	2020
2	Aspergillosis after liver transplantation in the context of common variable immunodeficiency: case report. ⁶¹	Chen Y...Cameron A	23676145	2013
3	Aspergillus galactomannan antigen for diagnosis and treatment monitoring in cerebral aspergillosis. ⁶¹	Soeffker G...Kluge S	23448824	2013
4	Neuroaspergillosis leading to blindness in a patient with multiple myeloma. ⁶¹	Butler S...Malone RJ	19884809	2010
5	[Successful treatment of neuroaspergillosis in a patient with acute lymphoblastic leukemia: role of surgery, systemic antifungal therapy and intracavitary therapy]. ⁶¹	Ozcelik T...Tunali A	19795628	2009
6	Cerebral aspergillosis: tissue penetration is the key. ⁶¹	Schwartz S...Thiel E	19255905	2009
7	Neuroaspergillosis in an immunocompetent patient successfully treated with voriconazole and a corticosteroid. ⁶¹	Hiraga A...Kamitsukasa I	19602790	2009
8	Neuroaspergillosis in an immunocompetent patient. ⁶¹	Sood S...Rishi S	17377359	2007
9	Neuroaspergillosis and brain tuberculosis in an immunocompetent patient with good outcome. ⁶¹	Renard JE...Mihout B	9527169	1998

Sources

Genes for Neuroaspergillosis

Genes related to Neuroaspergillosis (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	DYRK3	Dual Specificity Tyrosine Phosphorylation Regulated Kinase 3	Protein Coding	5.6	DISEASES inferred ¹⁵
2	GART	Phosphoribosylglycinamide Formyltransferase, Phosphoribosylglycinamide Synthetase, Phosphoribosylaminoimidazole Synthetase	Protein Coding	4.64	DISEASES inferred ¹⁵
3	SMPD2	Sphingomyelin Phosphodiesterase 2	Protein Coding	4.62	DISEASES inferred ¹⁵
4	CYP51A1	Cytochrome P450 Family 51 Subfamily A Member 1	Protein Coding	4.56	DISEASES inferred ¹⁵
5	LINC01554	Long Intergenic Non-Protein Coding RNA 1554	RNA Gene	4.54	DISEASES inferred ¹⁵

Sources

Variations for Neuroaspergillosis

Sources

Expression for Neuroaspergillosis

Search GEO for disease gene expression data for Neuroaspergillosis.

Sources

Pathways for Neuroaspergillosis

Sources

GO Terms for Neuroaspergillosis

Sources

Sources for Neuroaspergillosis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia