MCID: NRH002
MIFTS: 23

Neurohypophysis Granular Cell Tumor

Categories: Cancer diseases, Endocrine diseases, Neuronal diseases
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Aliases & Classifications for Neurohypophysis Granular Cell Tumor

MalaCards integrated aliases for Neurohypophysis Granular Cell Tumor:

Name: Neurohypophysis Granular Cell Tumor 11 14
Granular Cell Tumor of the Neurohypophysis 16

Classifications:



External Ids:

Disease Ontology 11 DOID:5047
NCIt 49 C7017
SNOMED-CT 68 699331002
UMLS 71 C1333873

Summaries for Neurohypophysis Granular Cell Tumor

MalaCards based summary: Neurohypophysis Granular Cell Tumor, also known as granular cell tumor of the neurohypophysis, is related to granular cell tumor and neuroendocrine tumor. An important gene associated with Neurohypophysis Granular Cell Tumor is NKX2-1 (NK2 Homeobox 1), and among its related pathways/superpathways is Neuroscience. Affiliated tissues include pituitary, and related phenotypes are nervous system and behavior/neurological

Related Diseases for Neurohypophysis Granular Cell Tumor

Diseases related to Neurohypophysis Granular Cell Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 251)
# Related Disease Score Top Affiliating Genes
1 granular cell tumor 30.8 SYP NKX2-1 ENO2 CALB2
2 neuroendocrine tumor 29.1 SYP NKX2-1 NCAM1 ENO2 CALCA
3 rare tumor 10.5
4 hyperprolactinemia 10.4
5 central precocious puberty 10.4
6 pituitary adenoma 10.4
7 hypopituitarism 10.4
8 precocious puberty 10.4
9 hypothyroidism, congenital, nongoitrous, 2 10.2
10 pituitary hormone deficiency, combined, 2 10.2
11 thyrotropin-releasing hormone deficiency 10.2
12 toe syndactyly, telecanthus, and anogenital and renal malformations 10.2
13 oncocytoma 10.2
14 hypothyroidism, congenital, nongoitrous, 3 10.2
15 amenorrhea 10.2
16 acromegaly 10.2
17 functioning pituitary adenoma 10.2
18 adenoma 10.2
19 intracranial hypertension 10.2
20 lymphohistiocytoid mesothelioma 10.2 NKX2-1 CALB2
21 pleomorphic carcinoma 10.2 NKX2-1 CALB2
22 lung sarcomatoid carcinoma 10.2 NKX2-1 CALB2
23 sternum lymphoma 10.2 NKX2-1 NCAM1
24 sternum cancer 10.2 NKX2-1 NCAM1
25 adenomatoid tumor 10.1 NKX2-1 CALB2
26 rete testis adenoma 10.1 NCAM1 CALB2
27 solid adenocarcinoma with mucin production 10.1 NKX2-1 NCAM1
28 fallopian tube carcinosarcoma 10.1 NCAM1 CALB2
29 pacinian tumor 10.1 ENO2 CALB2
30 benign mesothelioma 10.1 NKX2-1 CALB2
31 cholangiolocellular carcinoma 10.1 NCAM1 CHL1
32 infected hydrocele 10.1 NCAM1 CALB2
33 spindle cell thymoma 10.1 ENO2 CALB2
34 adult type testicular granulosa cell tumor 10.1 NCAM1 CALB2
35 thymus basaloid carcinoma 10.1 SYP NKX2-1
36 lung meningioma 10.1 SYP NKX2-1
37 ovarian serous cystadenofibroma 10.1 NCAM1 CALB2
38 ovarian serous adenofibroma 10.1 NCAM1 CALB2
39 ovarian cystic teratoma 10.1 SYP NKX2-1
40 leydig cell tumor 10.1 SYP CALB2
41 ovarian sex-cord stromal tumor 10.1 NCAM1 CALB2
42 chordoid glioma 10.1 SYP NKX2-1
43 sex cord-gonadal stromal tumor 10.1 NKX2-1 CALB2
44 papillary adenoma 10.1 SYP NKX2-1
45 keratinizing squamous cell carcinoma 10.1 SYP NKX2-1
46 intestinal perforation 10.1 NKX2-1 NCAM1
47 krukenberg carcinoma 10.1 SYP CALB2
48 sclerosing hemangioma 10.0 SYP NKX2-1
49 pulmonary sclerosing hemangioma 10.0 SYP NKX2-1
50 struma ovarii 10.0 SYP NKX2-1

Graphical network of the top 20 diseases related to Neurohypophysis Granular Cell Tumor:



Diseases related to Neurohypophysis Granular Cell Tumor

Symptoms & Phenotypes for Neurohypophysis Granular Cell Tumor

MGI Mouse Phenotypes related to Neurohypophysis Granular Cell Tumor:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.5 CALB2 CALCA CHL1 ENO2 NCAM1 NKX2-1
2 behavior/neurological MP:0005386 9.23 CALB2 CALCA CHL1 ENO2 NCAM1 NKX2-1

Drugs & Therapeutics for Neurohypophysis Granular Cell Tumor

Search Clinical Trials, NIH Clinical Center for Neurohypophysis Granular Cell Tumor

Genetic Tests for Neurohypophysis Granular Cell Tumor

Anatomical Context for Neurohypophysis Granular Cell Tumor

Organs/tissues related to Neurohypophysis Granular Cell Tumor:

MalaCards : Pituitary

Publications for Neurohypophysis Granular Cell Tumor

Articles related to Neurohypophysis Granular Cell Tumor:

(show all 22)
# Title Authors PMID Year
1
Squash smear cytology of pituitary granular cell tumor: A case report and review of literature with special emphasis on cytological differential diagnosis in pituitary region. 62
32926559 2021
2
Aggressive granular cell tumor of the neurohypophysis with optic tract edema and invasion into third ventricle. 62
31819811 2019
3
Granular Cell Tumor of the Neurohypophysis: 3 Cases and a Systematic Literature Review of 98 Cases. 62
30017767 2018
4
Sellar and suprasellar granular cell tumor of the neurohypophysis: A rare case report and review of the literature. 62
29271018 2018
5
Clinical and imaging features of granular cell tumor of the neurohypophysis: A retrospective analysis. 62
29489677 2018
6
Granular Cell Tumor of the Neurohypophysis With TFE-3 Expression: A Rare Case Report. 62
28612665 2017
7
Overview of the 2017 WHO Classification of Pituitary Tumors. 62
28766057 2017
8
Suprasellar granular cell tumor of the neurohypophysis: surgical outcome of a very rare tumor. 62
26753850 2016
9
Granular cell tumor of the neurohypophysis: a single-institution experience. 62
25296610 2014
10
Granular cell tumor of the neurohypophysis with optic tract edema. 62
24414885 2014
11
Suprasellar granular cell tumor of the neurohypophysis in a child: unusual presentation in pediatric age of a rare tumor. 62
23463129 2013
12
Granular cell tumor of the neurohypophysis: case report and review of the literature. 62
23922042 2013
13
[Granular cell tumor of the neurohypophysis observed with hypoglycemic attack]. 62
22824579 2012
14
Granular cell tumor of the neurohypophysis: report of a case with intraoperative cytologic diagnosis. 62
18064694 2008
15
Granular cell tumor of the neurohypophysis: report of a case with unusual age presentation. 62
16133355 2005
16
Symptomatic granular cell tumor of the neurohypophysis. 62
15026860 2004
17
A case of atypical granular cell tumor of the neurohypophysis. 62
10886742 2000
18
Acromegaly associated with a granular cell tumor of the neurohypophysis: a clinical and histological study. Case report. 62
10883914 2000
19
MR imaging findings in granular cell tumor of the neurohypophysis: a difficult preoperative diagnosis. 62
11305562 2000
20
Atypical granular cell tumor of the neurohypophysis: a case report with review of the literature. 62
9737119 1998
21
[An immunohistochemical and ultrastructural study of granular cell tumor of the neurohypophysis]. 62
7857415 1994
22
Granular cell tumor of the neurohypophysis. 62
13340055 1956

Variations for Neurohypophysis Granular Cell Tumor

Expression for Neurohypophysis Granular Cell Tumor

Search GEO for disease gene expression data for Neurohypophysis Granular Cell Tumor.

Pathways for Neurohypophysis Granular Cell Tumor

Pathways related to Neurohypophysis Granular Cell Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.55 SYP NKX2-1 NCAM1 ENO2 CALCA

GO Terms for Neurohypophysis Granular Cell Tumor

Cellular components related to Neurohypophysis Granular Cell Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 terminal bouton GO:0043195 9.43 SYP CALCA CALB2
2 neuron projection GO:0043005 9.23 SYP NCAM1 ENO2 CALCA CALB2

Sources for Neurohypophysis Granular Cell Tumor

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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