Neurohypophysis Granular Cell Tumor disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Neurohypophysis Granular Cell Tumor

MalaCards integrated aliases for Neurohypophysis Granular Cell Tumor:

Name: Neurohypophysis Granular Cell Tumor ¹¹ ¹⁴

Granular Cell Tumor of the Neurohypophysis ¹⁶

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Endocrine diseases Neuronal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:5047

NCIt ⁴⁹ C7017

SNOMED-CT ⁶⁸ 699331002

EFO ¹⁶ EFO_1000285

UMLS ⁷¹ C1333873

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Summaries for Neurohypophysis Granular Cell Tumor

MalaCards based summary: Neurohypophysis Granular Cell Tumor, also known as granular cell tumor of the neurohypophysis, is related to granular cell tumor and neuroendocrine tumor. An important gene associated with Neurohypophysis Granular Cell Tumor is NKX2-1 (NK2 Homeobox 1), and among its related pathways/superpathways is Neuroscience. Affiliated tissues include pituitary, and related phenotypes are nervous system and behavior/neurological

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Related Diseases for Neurohypophysis Granular Cell Tumor

Diseases related to Neurohypophysis Granular Cell Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 251)

#	Related Disease	Score	Top Affiliating Genes
1	granular cell tumor	30.8	SYP NKX2-1 ENO2 CALB2
2	neuroendocrine tumor	29.1	SYP NKX2-1 NCAM1 ENO2 CALCA
3	rare tumor	10.5
4	hyperprolactinemia	10.4
5	central precocious puberty	10.4
6	pituitary adenoma	10.4
7	hypopituitarism	10.4
8	precocious puberty	10.4
9	hypothyroidism, congenital, nongoitrous, 2	10.2
10	pituitary hormone deficiency, combined, 2	10.2
11	thyrotropin-releasing hormone deficiency	10.2
12	toe syndactyly, telecanthus, and anogenital and renal malformations	10.2
13	oncocytoma	10.2
14	hypothyroidism, congenital, nongoitrous, 3	10.2
15	amenorrhea	10.2
16	acromegaly	10.2
17	functioning pituitary adenoma	10.2
18	adenoma	10.2
19	intracranial hypertension	10.2
20	lymphohistiocytoid mesothelioma	10.2	NKX2-1 CALB2
21	pleomorphic carcinoma	10.2	NKX2-1 CALB2
22	lung sarcomatoid carcinoma	10.2	NKX2-1 CALB2
23	sternum lymphoma	10.2	NKX2-1 NCAM1
24	sternum cancer	10.2	NKX2-1 NCAM1
25	adenomatoid tumor	10.1	NKX2-1 CALB2
26	rete testis adenoma	10.1	NCAM1 CALB2
27	solid adenocarcinoma with mucin production	10.1	NKX2-1 NCAM1
28	fallopian tube carcinosarcoma	10.1	NCAM1 CALB2
29	pacinian tumor	10.1	ENO2 CALB2
30	benign mesothelioma	10.1	NKX2-1 CALB2
31	cholangiolocellular carcinoma	10.1	NCAM1 CHL1
32	infected hydrocele	10.1	NCAM1 CALB2
33	spindle cell thymoma	10.1	ENO2 CALB2
34	adult type testicular granulosa cell tumor	10.1	NCAM1 CALB2
35	thymus basaloid carcinoma	10.1	SYP NKX2-1
36	lung meningioma	10.1	SYP NKX2-1
37	ovarian serous cystadenofibroma	10.1	NCAM1 CALB2
38	ovarian serous adenofibroma	10.1	NCAM1 CALB2
39	ovarian cystic teratoma	10.1	SYP NKX2-1
40	leydig cell tumor	10.1	SYP CALB2
41	ovarian sex-cord stromal tumor	10.1	NCAM1 CALB2
42	chordoid glioma	10.1	SYP NKX2-1
43	sex cord-gonadal stromal tumor	10.1	NKX2-1 CALB2
44	papillary adenoma	10.1	SYP NKX2-1
45	keratinizing squamous cell carcinoma	10.1	SYP NKX2-1
46	intestinal perforation	10.1	NKX2-1 NCAM1
47	krukenberg carcinoma	10.1	SYP CALB2
48	sclerosing hemangioma	10.0	SYP NKX2-1
49	pulmonary sclerosing hemangioma	10.0	SYP NKX2-1
50	struma ovarii	10.0	SYP NKX2-1

Graphical network of the top 20 diseases related to Neurohypophysis Granular Cell Tumor:

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Symptoms & Phenotypes for Neurohypophysis Granular Cell Tumor

MGI Mouse Phenotypes related to Neurohypophysis Granular Cell Tumor:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	nervous system	MP:0003631	9.5	CALB2 CALCA CHL1 ENO2 NCAM1 NKX2-1
2	behavior/neurological	MP:0005386	9.23	CALB2 CALCA CHL1 ENO2 NCAM1 NKX2-1

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Drugs & Therapeutics for Neurohypophysis Granular Cell Tumor

Search Clinical Trials, NIH Clinical Center for Neurohypophysis Granular Cell Tumor

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Genetic Tests for Neurohypophysis Granular Cell Tumor

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Anatomical Context for Neurohypophysis Granular Cell Tumor

Organs/tissues related to Neurohypophysis Granular Cell Tumor:

MalaCards : Pituitary

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Publications for Neurohypophysis Granular Cell Tumor

Articles related to Neurohypophysis Granular Cell Tumor:

(show all 22)

#	Title	Authors	PMID	Year
1	Squash smear cytology of pituitary granular cell tumor: A case report and review of literature with special emphasis on cytological differential diagnosis in pituitary region. ⁶²	Khurana U...Kapoor N	32926559	2021
2	Aggressive granular cell tumor of the neurohypophysis with optic tract edema and invasion into third ventricle. ⁶²	Dai Y...Bhabhra R	31819811	2019
3	Granular Cell Tumor of the Neurohypophysis: 3 Cases and a Systematic Literature Review of 98 Cases. ⁶²	Zhang Y...Yao Y	30017767	2018
4	Sellar and suprasellar granular cell tumor of the neurohypophysis: A rare case report and review of the literature. ⁶²	Jiang B...Fan C	29271018	2018
5	Clinical and imaging features of granular cell tumor of the neurohypophysis: A retrospective analysis. ⁶²	Han F...Zhang J	29489677	2018
6	Granular Cell Tumor of the Neurohypophysis With TFE-3 Expression: A Rare Case Report. ⁶²	Yang GZ...Li J	28612665	2017
7	Overview of the 2017 WHO Classification of Pituitary Tumors. ⁶²	Mete O...Lopes MB	28766057	2017
8	Suprasellar granular cell tumor of the neurohypophysis: surgical outcome of a very rare tumor. ⁶²	Gagliardi F...Mortini P	26753850	2016
9	Granular cell tumor of the neurohypophysis: a single-institution experience. ⁶²	Piccirilli M...Delfini R	25296610	2014
10	Granular cell tumor of the neurohypophysis with optic tract edema. ⁶²	Shizukuishi T...Sugitani M	24414885	2014
11	Suprasellar granular cell tumor of the neurohypophysis in a child: unusual presentation in pediatric age of a rare tumor. ⁶²	Gagliardi F...Mortini P	23463129	2013
12	Granular cell tumor of the neurohypophysis: case report and review of the literature. ⁶²	Saiegh L...Shechner C	23922042	2013
13	[Granular cell tumor of the neurohypophysis observed with hypoglycemic attack]. ⁶²	Suzuki R...Matsumura A	22824579	2012
14	Granular cell tumor of the neurohypophysis: report of a case with intraoperative cytologic diagnosis. ⁶²	Policarpio-Nicolas ML...Lopes MB	18064694	2008
15	Granular cell tumor of the neurohypophysis: report of a case with unusual age presentation. ⁶²	Benites Filho PR...Bleggi Torres LF	16133355	2005
16	Symptomatic granular cell tumor of the neurohypophysis. ⁶²	Lee CC...How SW	15026860	2004
17	A case of atypical granular cell tumor of the neurohypophysis. ⁶²	Kasashima S...Nakanishi I	10886742	2000
18	Acromegaly associated with a granular cell tumor of the neurohypophysis: a clinical and histological study. Case report. ⁶²	Losa M...Giovanelli M	10883914	2000
19	MR imaging findings in granular cell tumor of the neurohypophysis: a difficult preoperative diagnosis. ⁶²	Iglesias A...Fernandez R	11305562	2000
20	Atypical granular cell tumor of the neurohypophysis: a case report with review of the literature. ⁶²	Shuangshoti S...Shuangshoti S	9737119	1998
21	[An immunohistochemical and ultrastructural study of granular cell tumor of the neurohypophysis]. ⁶²	Lafitte C...Fetissof F	7857415	1994
22	Granular cell tumor of the neurohypophysis. ⁶²	GLAZER N...SLADE H	13340055	1956

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Genes for Neurohypophysis Granular Cell Tumor

Genes related to Neurohypophysis Granular Cell Tumor (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	NKX2-1	NK2 Homeobox 1	Protein Coding	5.27	DISEASES inferred ¹⁴
2	CHL1	Cell Adhesion Molecule L1 Like	Protein Coding	4.22	DISEASES inferred ¹⁴
3	CALB2	Calbindin 2	Protein Coding	4	DISEASES inferred ¹⁴
4	SDHB	Succinate Dehydrogenase Complex Iron Sulfur Subunit B	Protein Coding	3.82	DISEASES inferred ¹⁴
5	ENO2	Enolase 2	Protein Coding	3.46	DISEASES inferred ¹⁴
6	SYP	Synaptophysin	Protein Coding	3.38	DISEASES inferred ¹⁴
7	CALCA	Calcitonin Related Polypeptide Alpha	Protein Coding	3.28	DISEASES inferred ¹⁴
8	NCAM1	Neural Cell Adhesion Molecule 1	Protein Coding	3.17	DISEASES inferred ¹⁴

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Variations for Neurohypophysis Granular Cell Tumor

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Expression for Neurohypophysis Granular Cell Tumor

Search GEO for disease gene expression data for Neurohypophysis Granular Cell Tumor.

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Pathways for Neurohypophysis Granular Cell Tumor

Pathways related to Neurohypophysis Granular Cell Tumor according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Neuroscience ³	11.55	SYP NKX2-1 NCAM1 ENO2 CALCA

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GO Terms for Neurohypophysis Granular Cell Tumor

Cellular components related to Neurohypophysis Granular Cell Tumor according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	terminal bouton	GO:0043195	9.43	SYP CALCA CALB2
2	neuron projection	GO:0043005	9.23	SYP NCAM1 ENO2 CALCA CALB2

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MCID: NRH002 MIFTS: 23	Neurohypophysis Granular Cell Tumor Categories: Cancer diseases, Endocrine diseases, Neuronal diseases	Data Licensing For inquiries, contact: [email protected]
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