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MCID: NRN046
MIFTS: 19

Neuronal Tumor

Categories: Neuronal diseases, Rare diseases
Genes Tissues Related diseases Publications Drugs
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Aliases & Classifications for Neuronal Tumor

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MalaCards integrated aliases for Neuronal Tumor:

Name: Neuronal Tumor 58

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Neuronal diseases
See all MalaCards categories (disease lists)
Orphanet: 58  
Rare neurological diseases


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Orphanet 58 ORPHA251924
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Summaries for Neuronal Tumor

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MalaCards based summary : Neuronal Tumor is related to epilepsy and gangliocytoma. An important gene associated with Neuronal Tumor is BRAF (B-Raf Proto-Oncogene, Serine/Threonine Kinase). The drugs Etoposide and Valproic acid have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and pineal.

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Related Diseases for Neuronal Tumor

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Diseases related to Neuronal Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 24)
# Related Disease Score Top Affiliating Genes
1 epilepsy 9.9
2 gangliocytoma 9.9
3 neuroblastoma 9.9
4 glial tumor 9.9
5 rare tumor 9.9
6 congenital heart defects, hamartomas of tongue, and polysyndactyly 9.7
7 hydrocephalus 9.7
8 rabies 9.7
9 optic neuritis 9.7
10 lymphocytic choriomeningitis 9.7
11 central neurocytoma 9.7
12 neuritis 9.7
13 focal epilepsy 9.7
14 dysembryoplastic neuroepithelial tumor 9.7
15 pituitary adenoma 9.7
16 ganglioglioma 9.7
17 cowden syndrome 9.7
18 adenoma 9.7
19 intracranial hypertension 9.7
20 encephalitis 9.7
21 glioma 9.7
22 head injury 9.7
23 headache 9.7
24 paresthesia 9.7

Graphical network of the top 20 diseases related to Neuronal Tumor:



Diseases related to Neuronal Tumor
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Symptoms & Phenotypes for Neuronal Tumor

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Drugs & Therapeutics for Neuronal Tumor

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Drugs for Neuronal Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Etoposide Approved Phase 1 33419-42-0 36462
2
Valproic acid Approved, Investigational Phase 1 99-66-1 3121
3 Etoposide phosphate Phase 1
4 Neurotransmitter Agents Phase 1
5 Psychotropic Drugs Phase 1
6 Anticonvulsants Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Valproate (Valproic Acid) and Etoposide for Patients With Progressive, Relapsed or Refractory Neuronal Tumors and Brain Metastases Completed NCT00513162 Phase 1 Valproate;Etoposide
2 Multiparametric Imaging for Analysis of MVNT (Multinodular and Vacuolating Neuronal Tumor) Recruiting NCT04103190
3 High Resolution Imaging for Analysis of Multinodular and Vacuolating Neuronal Tumor of the Cerebrum Recruiting NCT04285125

Search NIH Clinical Center for Neuronal Tumor

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Genetic Tests for Neuronal Tumor

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Anatomical Context for Neuronal Tumor

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MalaCards organs/tissues related to Neuronal Tumor:

40
Spinal Cord, Brain, Pineal, Pituitary, Retina, Adrenal Gland, Temporal Lobe
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Publications for Neuronal Tumor

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Articles related to Neuronal Tumor:

(show top 50) (show all 134)
# Title Authors PMID Year
1
Multinodular and vacuolating neuronal tumor of the cerebrum: Two cases and review of the literature. 61
32979644 2020
2
Advanced multiparametric magnetic resonance imaging of multinodular and vacuolating neuronal tumor. 61
32301260 2020
3
Treatment and Outcomes for Central Nervous System Tumors in Australian Adolescents and Young Adults: A Population-Based National Study. 61
32856982 2020
4
Multinodular and vacuolating neuronal tumor associated with focal cortical dysplasia in a child with refractory epilepsy: a case report and brief review of literature. 61
31950248 2020
5
A multinodular and vacuolating neuronal tumor of the cerebrum (MVNT) with glioma-like appearance. 61
32632711 2020
6
Multinodular and vacuolating neuronal tumor of the cerebrum (MVNT): do not touch. 61
31201671 2020
7
Multinodular and Vacuolating Neuronal Tumor of the Cerebrum (MVNT): A case series and review of the literature. 61
31229580 2020
8
Infratentorial Multinodular and Vacuolating Neuronal Tumor or Multinodular and Vacuolating Posterior Fossa Lesions of Unknown Significance? Clinico-Radiologic Findings from 2 Cases. 61
31917314 2020
9
Magnetic resonance imaging findings of two cases with multinodular and vacuolating neuronal tumor. 61
29243173 2020
10
Low-grade developmental and epilepsy associated brain tumors: a critical update 2020. 61
32151273 2020
11
Neuronal Surface Antibody Syndrome: A Review of the Characteristics of the Disease and Its Association with Autoantibodies. 61
32554968 2020
12
BRAF Alteration in Central and Peripheral Nervous System Tumors. 61
33042847 2020
13
Atypical Presentation of Multinodular and Vacuolating Neuronal Tumor of the Cerebrum in a Boy. 61
32140033 2020
14
Repaglinide Silences the FOXO3/Lumican Axis and Represses the Associated Metastatic Potential of Neuronal Cancer Cells. 61
31861249 2019
15
Multinodular and Vacuolating Neuronal Tumor of the Cerebrum: Does the Name Require Review? 61
31753835 2019
16
Multinodular and Vacuolating Posterior Fossa Lesions of Unknown Significance. 61
31558497 2019
17
Clinicopathological and molecular analysis of multinodular and vacuolating neuronal tumors of the cerebrum. 61
30550736 2019
18
Multinodular and vacuolating neuronal tumor (MVNT): A presumably incidental and asymptomatic case in an intractable epilepsy patient. 61
31886439 2019
19
Multinodular and vacuolating neuronal tumor incidentally discovered in a young man: Conventional and advanced MRI features. 61
30108675 2018
20
Novel case of recurrent intraventricular atypical central neurocytoma with prominent gangliogliomatous differentiation in a 10-year-old boy with 10 years of follow up. 61
30039530 2018
21
Multinodular and Vacuolating Neuronal Tumor. 61
30337992 2018
22
Central neurocytoma represents a tumor consisting of diverse neuronal phenotypes. 61
29747899 2018
23
Multinodular and vacuolating neuronal tumors in epilepsy: dysplasia or neoplasia? 61
28833756 2018
24
Neuroimaging of Dilated Perivascular Spaces: From Benign and Pathologic Causes to Mimics. 61
29280227 2018
25
Patterns of care and survival outcomes in patients with an extraventricular neurocytoma: An individual patient data analysis of 201 cases. 61
29547155 2018
26
Multinodular and vacuolating neuronal tumor of the cerebrum is a clonal neoplasm defined by genetic alterations that activate the MAP kinase signaling pathway. 61
29428973 2018
27
Multiparametric Imaging Improves Confidence in the Diagnosis of Multinodular and Vacuolating Neuronal Tumor of the Cerebrum. 61
29051207 2018
28
Multinodular and Vacuolating Neuronal Tumor of the Cerebrum: A Benign Nonaggressive Cerebral Lesion. 61
29241217 2018
29
Multinodular and vacuolating neuronal tumor: A case report and literature review. 61
29629230 2018
30
Case of the Season: Multinodular and Vacuolating Neuronal Tumor. 61
29405953 2018
31
Multinodular and vacuolating neuronal tumor of the cerebrum. A rare entity. New case and review of the literature. 61
29111096 2018
32
Surgical treatment of neuronal-glial tumors of mesial-basal part of temporal lobe: Long term outcome and control of epilepsy in pediatric patients. 61
29029800 2018
33
Multinodular and vacuolating neuronal tumor in an adolescent with Klinefelter syndrome. 61
29038865 2017
34
Multinodular and Vacuolating Neuronal Tumor of the Cerebrum: A New "Leave Me Alone" Lesion with a Characteristic Imaging Pattern. 61
28705817 2017
35
Natural history of lesions with the MR imaging appearance of multinodular and vacuolating neuronal tumor. 61
28752311 2017
36
Multinodular vacuolating and neuronal tumor of the cerebrum. 61
28716873 2017
37
Multinodular and Vacuolating Neuronal Tumor: A Rare Seizure-associated Entity. 61
28505008 2017
38
C10ORF10/DEPP-mediated ROS accumulation is a critical modulator of FOXO3-induced autophagy. 61
28545464 2017
39
Bovine herpesviruses induce different cell death forms in neuronal and glial-derived tumor cell cultures. 61
27311457 2016
40
Ibuprofen intake increases exercise time to exhaustion: A possible role for preventing exercise-induced fatigue. 61
26589249 2016
41
Treatment Results of Gamma Knife Radiosurgery for Central Neurocytoma: Report of a Japanese Multi-Institutional Cooperative Study. 61
26987638 2016
42
Intraoperative high-field MRI maximizes the extent of resection in intraventricular central neurocytoma surgery. 61
26964476 2016
43
Multinodular and vacuolating neuronal tumor affecting amygdala and hippocampus: A quasi-tumor? 61
26644357 2016
44
Genome-wide methylation profiling identifies novel methylated genes in neuroblastoma tumors. 61
26786290 2016
45
Localized overexpression of alpha-internexin within nodules in multinodular and vacuolating neuronal tumors. 61
26073706 2015
46
Role of adjuvant radiation in the management of central neurocytoma: Experience from a tertiary cancer care center of India. 61
26960488 2015
47
Tetraventricular central neurocytoma: A rare presentation with imaging-pathologic correlation. 61
26752911 2015
48
Atypical extraventricular neurocytoma in a 3-year-old girl: case report with radiological-pathological correlation. 61
25894757 2015
49
Tissue Engineering Strategies as Tools for Personalized Meningioma Treatment. 61
25894852 2015
50
Multinodular and vacuolating neuronal tumor of the cerebrum. 61
25146549 2015
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Variations for Neuronal Tumor

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Expression for Neuronal Tumor

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Search GEO for disease gene expression data for Neuronal Tumor.
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Pathways for Neuronal Tumor

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GO Terms for Neuronal Tumor

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Sources for Neuronal Tumor

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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