MCID: NRN002
MIFTS: 31

Neuronitis

Categories: Neuronal diseases

Aliases & Classifications for Neuronitis

MalaCards integrated aliases for Neuronitis:

Name: Neuronitis 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:8117
NCIt 50 C34847
UMLS 70 C0027881

Summaries for Neuronitis

Disease Ontology : 12 A central nervous system disease that is characterized by neuron inflammation.

MalaCards based summary : Neuronitis is related to vestibular neuronitis and guillain-barre syndrome. An important gene associated with Neuronitis is BICDL1 (BICD Family Like Cargo Adaptor 1). The drugs Lidocaine and Memantine have been mentioned in the context of this disorder. Affiliated tissues include cortex, spinal cord and subthalamic nucleus.

Related Diseases for Neuronitis

Graphical network of the top 20 diseases related to Neuronitis:



Diseases related to Neuronitis

Symptoms & Phenotypes for Neuronitis

Drugs & Therapeutics for Neuronitis

Drugs for Neuronitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 230)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
2
Memantine Approved, Investigational Phase 4 19982-08-2 4054
3
Oxcarbazepine Approved Phase 4 28721-07-5 34312
4
Carbamazepine Approved, Investigational Phase 4 298-46-4 2554
5
Valproic acid Approved, Investigational Phase 4 99-66-1 3121
6
Betamethasone Approved, Vet_approved Phase 4 378-44-9 9782
7
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
8
Remifentanil Approved Phase 4 132875-61-7 60815
9
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
10
Ocrelizumab Approved, Investigational Phase 4 637334-45-3
11
Melatonin Approved, Nutraceutical, Vet_approved Phase 4 73-31-4 896
12 Anti-Infective Agents, Local Phase 4
13 Sodium Channel Blockers Phase 4
14 Diuretics, Potassium Sparing Phase 4
15 Dopamine Agents Phase 4
16 Excitatory Amino Acid Antagonists Phase 4
17 Antiparkinson Agents Phase 4
18 Calamus Phase 4
19 Analgesics Phase 4
20 Adrenergic Agents Phase 4
21 Neurotransmitter Agents Phase 4
22 Anti-Asthmatic Agents Phase 4
23 Immunologic Factors Phase 4
24 Analgesics, Non-Narcotic Phase 4
25 Adrenergic alpha-Agonists Phase 4
26 Adrenergic Agonists Phase 4
27 Hypnotics and Sedatives Phase 4
28 Narcotics Phase 4
29 Anesthetics, Intravenous Phase 4
30
Carbon monoxide Approved, Investigational Phase 3 630-08-0 281
31
Coal tar Approved Phase 3 8007-45-2
32
Trazodone Approved, Investigational Phase 2, Phase 3 19794-93-5 5533
33
Cilostazol Approved, Investigational Phase 3 73963-72-1 2754
34
Nabiximols Investigational Phase 2, Phase 3 56575-23-6
35 Immunoglobulin G Phase 3
36 Rho(D) Immune Globulin Phase 3
37 Immunoglobulins, Intravenous Phase 3
38 gamma-Globulins Phase 3
39 Anti-Anxiety Agents Phase 2, Phase 3
40 Antidepressive Agents Phase 2, Phase 3
41 Serotonin Uptake Inhibitors Phase 2, Phase 3
42 Ginkgo Phase 3
43 Vasodilator Agents Phase 3
44 Fibrinolytic Agents Phase 3
45 Phosphodiesterase 3 Inhibitors Phase 3
46 Phosphodiesterase Inhibitors Phase 3
47 Bronchodilator Agents Phase 3
48
Serotonin Investigational, Nutraceutical Phase 2, Phase 3 50-67-9 5202
49
Prednisone Approved, Vet_approved Phase 2 53-03-2 5865
50
Omeprazole Approved, Investigational, Vet_approved Phase 2 73590-58-6 4594

Interventional clinical trials:

(show top 50) (show all 421)
# Name Status NCT ID Phase Drugs
1 Distribution and Expression of Non-neuronal Transient Receptor Potential (TRPV) Ion Channels in Sensitive Skin Syndrome. Unknown status NCT01871883 Phase 4
2 Effects of Different Concentrations of Dexmedetomidine on Basal Ganglia Neuronal Activity (Local Field Potentials) in Parkinson's Disease Unknown status NCT02982512 Phase 4 Dexmedetomidine
3 Effect of Carbamazepine and Oxcarbazepine on Serum Neuron-specific Enolase and S100B in Focal Seizures Completed NCT02705768 Phase 4 Carbamazepine;Oxcarbazepine
4 Effects of Dexmedetomidine on Neuronal Activity in the Subthalamic Nucleus During Deep Brain Stimulation (DBS) Electrode Implantation Surgery Completed NCT01721460 Phase 4 Dexmedetomidine
5 Exercise in Elderly Individuals With Impaired Glucose Tolerance: Beneficial for Vasculature and Neurons? Completed NCT01219231 Phase 4
6 Effects of Memantine on the Magnetic Resonance Spectroscopy (MRS) Measures of Neuronal Integrity in Subjects at Risk for Alzheimer's Disease Completed NCT00933608 Phase 4 memantine;Placebo
7 Effect of Melatonin on Seizure Outcome, Neuronal Damage and Quality of Life in Patients With Generalized Epilepsy: A Randomized, add-on Placebo-controlled Clinical Trial Completed NCT03590197 Phase 4 Melatonin 3 mg
8 Neuronal Inertia´s Effect on Pharmacological Behavior Representation of Propofol Completed NCT01962285 Phase 4 propofol targel controlled infusion
9 Exploratory Study of the Natural History, Clinical Outcomes, and Neuronal Endplate Changes in Subjects Reporting Short Duration vs. Long Duration of Benefit for OnabotulinumtoxinA in Treatment of Chronic Migraine Completed NCT02037425 Phase 4 onabotulinumtoxinA
10 Changes in Regional Cerebral Blood Flow as an Indicator of Neuronal Activity in Patients Treated With Spinal Cord Stimulation for Low Back and Leg Pain Completed NCT00418301 Phase 4
11 Acute Unilateral Vestibulopathy and Corticosteroid Treatment Recruiting NCT02912182 Phase 4 Betamethasone;Placebo;Prednisolone
12 An Open-Label, Prospective, Single-arm, Multi-center Study to Assess Disease Activity and Biomarkers of Neuronal Damage in Minority Patients With Relapsing Multiple Sclerosis Receiving Treatment With Ocrelizumab Recruiting NCT04377555 Phase 4 Ocrelizumab
13 Effects of Anesthesia Drugs on Neuronal Activity in the Basal Ganglia and Thalamus During Deep Brain Stimulation Electrode Implantation Surgery Recruiting NCT03283150 Phase 4 Remifentanil;Propofol;Dexmedetomidine
14 A Long-term Follow-up Study of Patients in the Clinical Trials for Spinal Muscular Atrophy Receiving AVXS-101 Enrolling by invitation NCT04042025 Phase 4
15 Functional Vision Consequences of Rehabilitation for TBI Vision Loss Terminated NCT01214070 Phase 4
16 Neuroprotective Effect of Desflurane in the Experimental Study: the Impact if Desflurane Preconditioning on the Content of the Phosphorylated Form of GSK-3b in the Neurons of the Rat's Brain in the Model of Ischemia/Reperfusion Withdrawn NCT04287842 Phase 4 Desflurane;Sevoflurane
17 Analgesia of Fibula Free Flap Donor Site by Peri-Neuronal Catheter in Oro-Pharyngeal Carcinoma Surgery: Comparing Continuous Infusion of Local Anesthetic With Systemic Multimodal Analgesia Unknown status NCT00181038 Phase 3
18 Targeting Monoaminergic Neuronal Networks in the Parkinsonian Patients After Carbon Monoxide Intoxication Unknown status NCT02138864 Phase 3
19 The Efficacy of Steroid Therapy in Vestibular Neuritis Confirmed by Head Impulse Test: Prospective Randomized Controlled Study Completed NCT02098330 Phase 3 Ginkgo biloba & Methylprednisolone;Ginkgo biloba
20 A Fase II, Randomized, Double-Blind, Placebo-Controlled, Multicentre Study for the Safety and Efficacy on Spasticity Symptoms of a Cannabis Sativa Extract in Motor Neuron Disease Patients Completed NCT01776970 Phase 2, Phase 3 Cannabis Sativa extract Oromucosal spray
21 A European, Randomised, Double-blind, Active Comparator Controlled, Cross-over, Efficacy and Safety Study of a New 10% Ready To-use Liquid Human Intravenous Immunoglobulin (I10E) Versus Kiovig® in Patients With Multifocal Motor Neuropathy Completed NCT01951924 Phase 3 Biological : I10E (Human normal Immunoglobulin for intravenous administration 100mg/mL);Biological: Kiovig® (Human normal Immunoglobulin for intravenous administration 100mg/mL)
22 Effects of Transcranial Direct Current Stimulation on Postural Control: a Double-blind Randomized Controlled Trial. Completed NCT03759132 Phase 2, Phase 3
23 Phase 3, Open-Label, Single-Arm, Single-Dose Gene Replacement Therapy Clinical Trial for Patients With Spinal Muscular Atrophy Type 1 With One or Two SMN2 Copies Delivering AVXS-101 by Intravenous Infusion Completed NCT03461289 Phase 3
24 The Effect of Transcranial Direct Current Stimulation on Decision Making and Cognitive Flexibility in Gambling Disorder Completed NCT03477799 Phase 3
25 A Prospective, Double Blind, Randomized, Controlled Study to Evaluate the Safety and Efficacy of the Deep Transcranial Magnetic Stimulation (DTMS) (With the H-ADD Coil) Intended as an Aid to Smoking Cessation. Completed NCT02126124 Phase 3
26 A Prospective, Multicentric, Randomized, Double-blind, Parallel, Phase III Clinical Study to Assess Efficacy of PMZ-1620 Along With Standard Treatment in Patients of Acute Ischemic Stroke Recruiting NCT04047563 Phase 3 Normal Saline along with standard treatment;PMZ-1620 (sovateltide) along with standard treatment
27 Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial Recruiting NCT04302870 Phase 2, Phase 3 Memantine Hydrochloride Oral Solution;Trazodone Hydrochloride oral solution;Placebo oral solution
28 A Randomised, Double-blind, Single-centre Study on the Safety, Tolerability and Efficacy of Cannabis Based Medicine Extract (MediCabilis CBD Oil) in Slowing the Disease Progression in Amyotrophic Lateral Sclerosis or Motor Neurone Disease Patients Recruiting NCT03690791 Phase 3 MediCabilis CBD Oil;Placebo Oil
29 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 2 Study of Cu(II)ATSM in Patients With Amyotrophic Lateral Sclerosis/Motor Neuron Disease Recruiting NCT04082832 Phase 2, Phase 3 Cu(II)ATSM;Placebos
30 Effects of Transcranial Direct Current Stimulation Combined With Therapeutic Exercises in Patients With Parkinson's Disease: Randomized Clinical Trial Recruiting NCT03473522 Phase 2, Phase 3
31 Phase 3, Open-Label, Single-Arm, Single-Dose Gene Replacement Therapy Clinical Trial for Patients With Spinal Muscular Atrophy Type 1 With One or Two SMN2 Copies Delivering AVXS-101 by Intravenous Infusion Active, not recruiting NCT03837184 Phase 3
32 A Single-center, Prospective, Randomized, Parallel Group, Placebo-controlled Exploratory Study on the Effect of Renexin Tablet in Patients With Recurrent Vestibulopathy Terminated NCT01895400 Phase 3 Renexin (cilostazol 100mg + gingko biloba extract 80 mg);Placebo
33 Phase II Study of the Effects of Erythropoietin on Neuronal Cell Death in Traumatic Brain Injury Patients Withdrawn NCT00260052 Phase 2, Phase 3 Erythropoietin administration
34 Transcranial Direct Current Stimulation in Rehabilitation of Chronic Stroke Patients: Multicenter Clinical Trial Unknown status NCT02166619 Phase 2
35 Autologous Purified Bone-Marrow-Derived Stem Cell Therapy for Motor Neuron Disease Unknown status NCT03067857 Phase 1, Phase 2
36 Transcranial Direct Current Stimulation in the Visual Cortex of Migraine Patients: Neurophysiological and Clinical Implications Unknown status NCT01886274 Phase 2
37 Prednisone Treatment for Vestibular Neuronitis Completed NCT00271791 Phase 2 Prednisone;Prednisone
38 Complementary/Alternative Medicine for Vestibulopathy Completed NCT00032383 Phase 1, Phase 2
39 l Prospective Clinical Investigation on the Acoustic Stimulation With the "Coordinated Reset of Neural Subpopulations" in the Treatment of Chronic Tinnitus Completed NCT00927121 Phase 1, Phase 2
40 A Prospective, Multicentric, Randomized, Double Blind, Parallel, Saline Controlled Phase II Clinical Study to Compare the Safety and Efficacy of PMZ-1620 Therapy Along With Standard Supportive Care in Subjects of Acute Ischemic Stroke Completed NCT04046484 Phase 2 Normal Saline along with standard treatment;PMZ-1620 along with standard treatment
41 Effect of Functional Exercise in Patients With Spinal and Bulbar Muscular Atrophy Completed NCT01369901 Phase 1, Phase 2
42 Phase II, Randomized, Placebo Controlled Trial of the Safety and Tolerability of Mycophenolate in Children With Juvenile Neuronal Ceroid Lipofuscinosis Completed NCT01399047 Phase 2 Mycophenolate mofetil;Liquid Placebo
43 A Prospective, Non-randomized, Open Label Study to Assess the Safety and the Efficacy of Autologous Multipotent Mesenchymal Stromal Cells in the Treatment of Amyotrophic Lateral Sclerosis Completed NCT03828123 Phase 1, Phase 2
44 Direct CNS Administration of a Replication Deficient Adeno-associated Virus Gene Transfer Vector Serotype rh.10 Expressing the Human CLN2 cDNA to Children With LINCL With Uncommon Genotypes and/or Moderate to Severe Impairment Completed NCT01414985 Phase 1, Phase 2
45 A Pilot Trial of Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease Completed NCT00324454 Phase 2
46 Neuronal Correlates of Neurexan® Action in Mildly to Moderately Stressed Probands - A Randomized, Placebo-controlled, Double-blind, Cross-over Trial of Mode of Action and Response Prediction by Functional Magnetic Resonance Imaging MRI Completed NCT02602275 Phase 2 Neurexan®
47 A Multicenter, 2-Part, 6-Week, Double-blind, Randomized, Placebo-controlled, Parallel-design Study to Assess the Efficacy and Safety of AEVI-001 in Children and Adolescents (Ages 6-17 Years) With Attention Deficit Hyperactivity Disorder and With or Without Copy Number Variants in Specific Genes Implicated in Glutamatergic Signaling and Neuronal Connectivity Completed NCT03609619 Phase 2 AEVI-001;Placebo
48 A Phase 2 Pharmacodynamic Trial of Ezogabine (Retigabine) on Neuronal Excitability in Amyotrophic Lateral Sclerosis Completed NCT02450552 Phase 2 Ezogabine;Placebo
49 Phase II Study of Ixabepilone in Patients With Metastatic Breast Cancer and a Prospective Evaluation of Its Effects on the Ultrastructure of Neurons Completed NCT00627978 Phase 2 ixabepilone
50 A Randomized, Double-blind, Dose Ranging Study to Determine the Effect of Memantine on Functional Outcomes and Motor Neuron Degeneration in Patients With ALS Completed NCT00409721 Phase 2 Memantine

Search NIH Clinical Center for Neuronitis

Genetic Tests for Neuronitis

Anatomical Context for Neuronitis

MalaCards organs/tissues related to Neuronitis:

40
Cortex, Spinal Cord, Subthalamic Nucleus, Eye, Bone, Brain, Liver

Publications for Neuronitis

Articles related to Neuronitis:

(show top 50) (show all 331)
# Title Authors PMID Year
1
[Analysis of high frequency semicircular canal function test in patients with unilateral vestibular neuronitis in the acute phase]. 61
33794622 2021
2
Neurologists' Diagnostic Accuracy and Interspecialties' Diagnostic Concordance of Acute Vertigo: Observational Study at the Emergency Department in a Tertiary Center. 61
33646987 2021
3
Association between Ménière's disease and thyroid diseases: a nested case-control study. 61
33106572 2020
4
The Differential Diagnosis of Vertigo in Children: A Systematic Review of 2726 Cases. 61
29095392 2020
5
[Etiology and clinical symptoms of bilateral vestibulopathy]. 61
32628380 2020
6
[Clinical diagnosis and treatment of chronic dizziness]. 61
33459553 2020
7
Detection of intralabyrinthine abnormalities using post-contrast delayed 3D-FLAIR MRI sequences in patients with acute vestibular syndrome. 61
30413960 2019
8
Risk Factors for Tinnitus in 37,692 Patients Followed in General Practices in Germany. 61
30870350 2019
9
Steroids for Acute Vestibular Neuronitis-the Earlier the Treatment, the Better the Outcome? 61
30681432 2019
10
[Analysis of clinical features of secondary benign paroxysmal positional vertigo]. 61
30813689 2019
11
Demographic data and seasonal variation in peripheral vestibular disorders in ENT practices in Germany. 61
31256098 2019
12
[A role of vascular risk factors in the development of peripheral vestibulopathy]. 61
31825395 2019
13
[Recovery of vestibulo-ocular reflex in vestibular neuronitis depending on severity of vestibulo-ocular reflex damage]. 61
32027320 2019
14
Diagnoses of Dizziness- and Vertigo-related Disorders in ENT Practices in Germany. 61
29533336 2018
15
[Dizziness and vertigo associated with vestibular neuronitis: the approaches to the diagnostics and treatment]. 61
29953046 2018
16
Diagnosis and Treatment of Vestibular Neuritis/Neuronitis or Peripheral Vestibulopathy (PVP)? Open Questions and Possible Answers. 61
28346294 2017
17
Association between ambient particulate matter and disorders of vestibular function. 61
28236785 2017
18
[The diagnosis, treatment and aviation medicine identification of vestibular neuronitis]. 61
29871338 2017
19
[Benign paroxysmal positional vertigo: modern concepts of its etiology and pathogenesis]. 61
28631688 2017
20
[The peripheral vestibular disorders encountered in the routine out-patient practical work]. 61
28252586 2017
21
Clinical characteristics of headache or facial pain prior to the development of acute herpes zoster of the head. 61
27978460 2017
22
About the pathophysiology of acute unilateral vestibular deficit - vestibular neuritis (VN) or peripheral vestibulopathy (PVP)? 61
27392835 2016
23
An approach to vertigo in general practice. 61
27052132 2016
24
Pediatric stiff-person syndrome with renal failure. 61
26933366 2016
25
Chulalongkorn vestibular balance exercise for rehabilitation in persons with various types of vestibular disorders. 61
25764617 2015
26
[The level of beta-endorphin, chronic stress, and depression associated with vestibular pathology]. 61
25909666 2015
27
Use of betahistine in the treatment of peripheral vertigo. 61
26245698 2015
28
Vertigo with a Vestibular Dysfunction in Children During Respiratory Tract Infections. 61
26017723 2015
29
Central vestibular dysfunction in an otorhinolaryngological vestibular unit: incidence and diagnostic strategy. 61
25992098 2014
30
Is vestibular neuritis an immune related vestibular neuropathy inducing vertigo? 61
24741601 2014
31
[Otorhinolaryngological manifestations in patients with Behçet disease]. 61
24094428 2014
32
Bell's palsy and vestibular neuronitis. 61
25015516 2014
33
Investigation of seasonal variability of vestibular neuronitis. 61
24063368 2013
34
[The influence of otolithic afferentation on the vestibulo-ocular interaction in the patients presenting with an unilateral lesion in a peripheral vestibular neuron]. 61
23528462 2013
35
A perspective on recurrent vertigo. 61
23796949 2013
36
[Vestibular neuronitis: pathophysiology, diagnosis and treatment]. 61
23401980 2012
37
[Causal relationship: and if "yes", and if "not"... on basis of which criterias?]. 61
23133891 2012
38
Diagnosing the cause of vertigo: a practical approach. 61
22865178 2012
39
The clinical relevance of vertebral artery hypoplasia. 61
22879083 2012
40
[ENT]. 61
23185819 2012
41
The role of vestibular evoked myogenic potentials (VEMPs) in vestibulopathy diagnostics. 61
22616590 2012
42
Vestibular evoked myogenic potentials in vestibular neuronitis. 61
22368986 2011
43
Herpes simplex virus type 1 in saliva of patients with vestibular neuronitis: a preliminary study. 61
22045284 2011
44
[An oto-neurological approach to the acutely dizzy patient]. 61
21975186 2011
45
Treatment of acute vestibular neuronitis with glucocorticoids. 61
21817947 2011
46
Comorbid intracranial vertebral artery asymmetry as a risk factor for severe vestibular neuronitis. 61
21317672 2011
47
A clinical epidemiological study in 187 patients with vertigo. 61
20976571 2011
48
[Interdisciplinary approach to vestibular system impairment]. 61
21545007 2011
49
Vocal cord palsy: An uncommon presenting feature of myasthenia gravis. 61
21655204 2011
50
Dizziness in the emergency room: diagnoses and misdiagnoses. 61
21986277 2011

Variations for Neuronitis

Expression for Neuronitis

Search GEO for disease gene expression data for Neuronitis.

Pathways for Neuronitis

GO Terms for Neuronitis

Biological processes related to Neuronitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 modulation of chemical synaptic transmission GO:0050804 8.62 LRFN2 GRIK3

Sources for Neuronitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....