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MCID: NRP001
MIFTS: 63

Neuropathy

Categories: Neuronal diseases, Immune diseases, Rare diseases
Genes Variations Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Neuropathy

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MalaCards integrated aliases for Neuropathy:

Name: Neuropathy 12 15 40 73
Peripheral Neuropathy 12 73

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Neuronal diseases Immune diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:870
ICD10 33 G62.9
NCIt 50 C4731
UMLS 73 C0442874
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Summaries for Neuropathy

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Disease Ontology : 12 A nervous system disease that is located in nerves or nerve cells.

MalaCards based summary : Neuropathy, also known as peripheral neuropathy, is related to neuropathy, hereditary sensory and autonomic, type iia and neuropathy, hereditary sensory, type ie, and has symptoms including back pain, headache and neuralgia. An important gene associated with Neuropathy is DLX6-AS1 (DLX6 Antisense RNA 1
In this report,we show that the Dlx-5/6 ultraconserved region is transcribed to generate an alternatively spliced form of Evf-1,the ncRNA Evf-2. Evf-2 specifically cooperates with Dlx-2 to increase the transcriptional activity of the Dlx-5/6 enhancer in a target and homeodomain-specific manner. In order to test this hypothesis we used the C17 and MN9D neural cell lines.
Dysfunction Pattern: Regulation [up-regulated]), and among its related pathways/superpathways is Neural Crest Differentiation. The drugs Naproxen and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include nerves or nerve cells, lung and spinal cord, and related phenotypes are behavior/neurological and cellular

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Related Diseases for Neuropathy

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Diseases in the Neuropathy family:

Autoimmune Neuropathy Hereditary Type 1 Neuropathy
Hereditary Type 2 Neuropathy Hereditary Neuropathies

Diseases related to Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1422)
# Related Disease Score Top Affiliating Genes
1 neuropathy, hereditary sensory and autonomic, type iia 35.0 KIF1A WNK1
2 neuropathy, hereditary sensory, type ie 34.9 SPTLC1 SPTLC2
3 hereditary sensory and autonomic neuropathy type 1 34.9 SPTLC1 SPTLC2
4 neuropathy, hereditary, with liability to pressure palsies 34.7 GDAP1 GJB1 MFN2 MPZ PMP22
5 hypertrophic neuropathy of dejerine-sottas 34.7 GDAP1 GJB1 MPZ PMP22
6 hereditary neuropathy with liability to pressure palsy 34.7 MPZ PMP22
7 hereditary neuropathies 34.7 GJB1 MFN2 MPZ PMP22
8 neuropathy, congenital hypomyelinating or amyelinating, autosomal recessive 34.6 GDAP1 GJB1 MFN2 MPZ PMP22
9 diabetic neuropathy 34.6 MPZ NGF PMP22
10 hereditary motor and sensory neuropathy, type iic 34.5 GDAP1 GJB1 MFN2 MPZ
11 motor peripheral neuropathy 34.4 GJB1 MFN2 MPZ PMP22
12 hereditary sensory neuropathy 34.4 KIF1A NGF SPTLC1 SPTLC2 WNK1
13 autonomic neuropathy 34.4 KIF1A NGF SPTLC1 SPTLC2 WNK1
14 charcot-marie-tooth disease, demyelinating, type 1b 34.3 GJB1 MPZ PMP22
15 congenital hypomyelination neuropathy 34.3 MPZ PMP22
16 charcot-marie-tooth neuropathy type 1 34.3 GJB1 MPZ PMP22
17 charcot-marie-tooth disease, axonal, type 2b 34.2 GJB1 MPZ PMP22 SPTLC1
18 charcot-marie-tooth disease, demyelinating, type 1c 34.2 MPZ PMP22
19 charcot-marie-tooth disease, x-linked dominant, 1 34.1 GDAP1 GJB1 MPZ
20 sensory neuropathy type 1 34.1 GJB1 SPTLC1
21 charcot-marie-tooth disease, demyelinating, type 1d 34.0 GJB1 MPZ PMP22
22 brachial plexus neuropathy 34.0 GJB1 PMP22
23 charcot-marie-tooth disease, demyelinating, type 1f 34.0 GJB1 MPZ PMP22
24 charcot-marie-tooth disease, type 4d 34.0 GDAP1 GJB1 MFN2
25 charcot-marie-tooth disease, axonal, type 2e 34.0 GAN GDAP1 GJB1 MFN2 MPZ PMP22
26 sensory peripheral neuropathy 34.0 GDAP1 GJB1 MFN2 MPZ NGF PMP22
27 charcot-marie-tooth disease, axonal, type 2f 33.9 GJB1 MPZ
28 axonal neuropathy 33.8 GAN GDAP1 MFN2 PMP22 POLG
29 charcot-marie-tooth disease, axonal, type 2k 33.8 GDAP1 KIF1A MFN2
30 charcot-marie-tooth disease, demyelinating, type 1a 33.7 GDAP1 GJB1 MFN2 MPZ PMP22
31 charcot-marie-tooth disease and deafness 33.7 GDAP1 GJB1 MFN2 MPZ PMP22
32 roussy-levy hereditary areflexic dystasia 33.4 MPZ PMP22
33 foot drop 32.9 MPZ PMP22
34 polyneuropathy 32.8 GDAP1 MPZ PMP22 PNPLA6
35 charcot-marie-tooth disease 32.7 AIFM1 GAN GDAP1 GJB1 MFN2 MPZ
36 peripheral nervous system disease 32.7 GAN GDAP1 GJB1 MFN2 MPZ MT-ND4
37 autonomic dysfunction 32.5 SPTLC1 WNK1
38 cranial nerve disease 32.0 MFN2 MT-ND4 POLG
39 spastic paraplegia 7, autosomal recessive 31.7 MFN2 MT-ND4
40 tooth disease 31.5 GDAP1 GJB1 MFN2 MPZ PMP22
41 neuritis 31.4 MPZ MT-ND4 PMP22
42 amyotrophic neuralgia 31.1 GJB1 PMP22
43 chronic inflammatory demyelinating polyradiculoneuropathy 30.2 MPZ PMP22
44 cortical blindness 29.7 MT-ND4 POLG
45 nervous system disease 29.4 DLX6-AS1 MT-ND4 NGF
46 agenesis of the corpus callosum with peripheral neuropathy 12.3
47 neuropathy, hereditary sensory and autonomic, type v 12.3
48 nonarteritic anterior ischemic optic neuropathy 12.3
49 neuropathy, hereditary sensory and autonomic, type vii 12.2
50 neuromyotonia and axonal neuropathy, autosomal recessive 12.2

Graphical network of the top 20 diseases related to Neuropathy:



Diseases related to Neuropathy
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Symptoms & Phenotypes for Neuropathy

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UMLS symptoms related to Neuropathy:


back pain, headache, neuralgia, pain, sciatica, seizures, syncope, tremor, chronic pain, atypical facial pain, neurologic symptoms, vertigo/dizziness, sleeplessness, hemiparesis

MGI Mouse Phenotypes related to Neuropathy:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.21 MPZ GDAP1 NGF GJB1 AIFM1 KIF1A
2 cellular MP:0005384 10.18 GAN MPZ GDAP1 GJB1 GP1BA AIFM1
3 homeostasis/metabolism MP:0005376 10.17 GDAP1 NGF GJB1 GP1BA AIFM1 DIAPH3
4 growth/size/body region MP:0005378 10.15 GAN NGF GJB1 AIFM1 KIF1A DIAPH3
5 mortality/aging MP:0010768 10 MPZ NGF GJB1 AIFM1 KIF1A DIAPH3
6 integument MP:0010771 9.86 NGF AIFM1 KIF1A DIAPH3 POLG SCN11A
7 muscle MP:0005369 9.5 GAN NGF AIFM1 MFN2 POLG PMP22
8 nervous system MP:0003631 9.47 GDAP1 NGF GJB1 PMP22 AIFM1 KIF1A
Sources

Drugs & Therapeutics for Neuropathy

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Drugs for Neuropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1038)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Naproxen Approved, Vet_approved Phase 4,Phase 3,Phase 2 22204-53-1 1302 156391
2
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 137-58-6 3676
3
Tazobactam Approved Phase 4,Phase 3 89786-04-9 123630
4
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 174722-31-7 10201696
5
Gemcitabine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 95058-81-4 60750
6
Dorzolamide Approved Phase 4,Not Applicable 120279-96-1 3154 5284549
7
Sulfamethoxazole Approved Phase 4,Not Applicable 723-46-6 5329
8
Pioglitazone Approved, Investigational Phase 4,Not Applicable 111025-46-8 4829
9
Remifentanil Approved Phase 4,Phase 3,Not Applicable 132875-61-7 60815
10
Simvastatin Approved Phase 4,Phase 3,Phase 2 79902-63-9 54454
11
Ciprofloxacin Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 85721-33-1 2764
12
Carboplatin Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 41575-94-4 10339178 498142 38904
13
Imipramine Approved Phase 4 50-49-7 3696
14
Etoricoxib Approved, Investigational Phase 4,Phase 2 202409-33-4 123619
15
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 2180-92-9, 38396-39-3 2474
16
Dopamine Approved Phase 4,Phase 3,Phase 2,Not Applicable 51-61-6, 62-31-7 681
17
Hydroxocobalamin Approved Phase 4,Phase 3,Phase 2,Not Applicable 13422-51-0 11953898 44475014
18
Minocycline Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 10118-90-8 5281021
19
Acetylcholine Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 51-84-3 187
20
Ephedrine Approved Phase 4,Phase 1,Not Applicable 299-42-3 9294
21
Trimethoprim Approved, Vet_approved Phase 4,Not Applicable 738-70-5 5578
22
Timolol Approved Phase 4,Phase 3,Phase 1,Not Applicable 26839-75-8 33624 5478
23
Pseudoephedrine Approved Phase 4,Phase 1,Not Applicable 90-82-4 7028
24
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1959-05-2, 59-05-2 126941
25
Tramadol Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 27203-92-5 33741
26
Norepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-41-2 439260
27
Ofloxacin Approved Phase 4,Phase 2,Phase 3,Not Applicable 82419-36-1 4583
28
Linezolid Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 165800-03-3 441401
29
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-78-2 2244
30
Carbamazepine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 298-46-4 2554
31
Diclofenac Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 15307-86-5 3033
32
Ketamine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 6740-88-1 3821
33
Gabapentin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 60142-96-3 3446
34
Amitriptyline Approved Phase 4,Phase 3,Phase 2,Not Applicable 50-48-6 2160
35
Morphine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 57-27-2 5288826
36
Fexofenadine Approved, Investigational Phase 4 83799-24-0 3348
37
Capsaicin Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 404-86-4 1548943
38
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2,Not Applicable 59467-70-8 4192
39
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 148553-50-8 5486971
40
Metronidazole Approved Phase 4,Phase 3,Phase 2 443-48-1 4173
41
Nitric Oxide Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 10102-43-9 145068 160954
42
Colistin Approved Phase 4 1264-72-8, 1066-17-7 5311054
43
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 50-02-2 5743
44
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 124-94-7 31307
45
Naloxone Approved, Vet_approved Phase 4,Phase 2 465-65-6 5284596
46
Oxycodone Approved, Illicit, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 76-42-6 5284603
47
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 50-24-8 5755
48
Piperacillin Approved Phase 4,Phase 3 66258-76-2 43672
49
Oxaliplatin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 61825-94-3 5310940 9887054 43805 6857599
50
Stavudine Approved, Investigational Phase 4,Phase 3 3056-17-5 18283

Interventional clinical trials:

(show top 50) (show all 3469)
# Name Status NCT ID Phase Drugs
1 Bi-Axial Rotating Magnetic Field Therapy in Refractory Neuropathic Foot Pain Secondary to Diabetic Peripheral Neuropathy Unknown status NCT00123136 Phase 4
2 Evaluation of the Impact of Training on Outcome Measures in Subjects With Painful Diabetic Neuropathy Unknown status NCT01770964 Phase 4 Pregabalin;placebo
3 Omega-3 Fatty Acids and Chemotherapy-induced Neuropathy and Inflammation in Breast Cancer Unknown status NCT01049295 Phase 4
4 Inspiratory Muscle Training in Patients With Autonomic Neuropathic Unknown status NCT00752440 Phase 4
5 The Impact of Perioperative Gabapentin on Chronic Groin Pain After Inguinal Hernia Repair Unknown status NCT02419443 Phase 4 Gabapentin;Placebo
6 Evaluation of Viral Efficacy and Safety of a Reduced Dose of Stavudine (d4T): THE PHOENIX STUDY Unknown status NCT00235222 Phase 4 stavudine
7 Chronic Treatment With Benfotiamine Restores Endothelial Function in People With Type 2 Diabetes Mellitus Unknown status NCT00446810 Phase 4 Benfotiamine;Placebo
8 Influence of Nitrates on Bone Remodeling and Endothelial Function in Patients With Type 2 Diabetes Mellitus Unknown status NCT02011620 Phase 4
9 Muscular Electrostimulation of the Sedated and Mechanically Ventilated Critically Ill Patient. Analysis of the Effect on Acquired Muscular Weakness and Its Clinical Consequences. Unknown status NCT02033057 Phase 4
10 Impact of Timolol/Dorzolamide Therapy on Autoregulation in Glaucoma Patients Unknown status NCT02053298 Phase 4 Timolol & Dorzolamide
11 Pregabalin for the Treatment of Uremic Pruritus Unknown status NCT01852318 Phase 4 pregabalin 75mg daily for 12 weeks;fexofenadine 60 mg daily for 12 weeks;placebo
12 Colistin Pharmacokinetics in Continuous Renal Replacement Therapy Unknown status NCT02081560 Phase 4 Colistin
13 Duration of Antibiotic Therapy in Community - Acquired Pneumonia Unknown status NCT01492387 Phase 4
14 IV Paracetamol vs IV Morphine vs Placebo in Sciatalgia Unknown status NCT02504996 Phase 4 Paracetamol;morphine;Placebo
15 Comparison of Intravenous Ibuprofen and Paracetamol in Patients With Sciatica Presented to the Emergency Department Unknown status NCT02777320 Phase 4 paracetamol;Ibuprofen
16 Maggot Debridement Therapy Versus Conventional Dressing Therapy to Treat Diabetic Foot Ulcers Unknown status NCT02816749 Phase 4
17 A Comparative Efficacy Study of DermaPureâ„¢ to Treat Diabetic Foot Ulcers Unknown status NCT02081352 Phase 4
18 Efficacy and Safety of Garamycin® Sponge (Gentamicin-Collagen Sponge) in Diabetic Patients With a Moderate or Severe Foot Ulcer Infection Unknown status NCT01951768 Phase 4 Garamycin Sponge (Gentamicin-Collagen sponge);Systemic Antibiotic
19 Clinical Evaluation of the SNaP Wound Care System Unknown status NCT01113658 Phase 4
20 A Post-marketing Evaluation of a Compound Traditional Chinese Herbal Medicine, Qishe Pill, on Cervical Radiculopathy Unknown status NCT01875562 Phase 4 Qishe Pill
21 Imipramine and Pregabalin Combination in Painful Polyneuropathy Unknown status NCT01047488 Phase 4 Imipramine;Pregabalin;Imipramine, pregabalin;Placebo
22 Determination of the Antidepressant Duloxetine in Plasma to Improve the Knowledge of the Analgesic Action of Antidepressants on Chronic Neuropathic Pain Unknown status NCT02846701 Phase 4 duloxetine
23 Evaluation of the Efficacy, Tolerability and Safety of Etoricoxib (Arcoxia) in Patients With Neuropathic Pain Unknown status NCT01264237 Phase 4 Etoricoxib;Placebo
24 Conservative Versus Aggressive Discectomy for Primary Disc Herniation With Radiculopathy Unknown status NCT01204008 Phase 4
25 Preventing Pain After Heart Surgery Unknown status NCT01480765 Phase 4 Pregabalin;Ketamine infusion;Placebo capsules;Placebo infusion
26 Qutenza for Critical Ischaemia in End Stage Renal Failure Unknown status NCT01704339 Phase 4 QUTENZA
27 A Phase IV Trial of Neuroprotection With ACTH in Acute Optic Neuritis Unknown status NCT01838174 Phase 4 ACTHAR Gel (ACTH);IV steroids with oral taper
28 Pregabalin for the Treatment and Prevention of Spinal Cord Injury Neuropathic Pain Unknown status NCT01479556 Phase 4 Pregabalin;Placebo
29 Effects of Pregabalin on Mechanical Hyperalgesia Unknown status NCT00310583 Phase 4 Pregabalin
30 Safety and Efficacy of Mecobalamin Injection in Peripheral Neuropathies Patients (Study JGAZSY091109) Completed NCT01192113 Phase 4 Mecobalamin IV Injection;Mecobalamin IM injection;Mecobalamin IV or IM injection
31 The Effect of α-lipoic Acid Treatment in Patient With Cardiac Autonomic Neuropathy Completed NCT02056366 Phase 4 α-lipoic acid
32 Frequency Modulated Neural Stimulation (FREMS) in Symptomatic Diabetic Neuropathy Completed NCT01628627 Phase 4
33 A Randomized Double-Blind Study Testing the Effects of Pregabalin on Diabetic Neuropathy Completed NCT00573261 Phase 4 Pregabalin;Placebo
34 Effect of Pulsing Electrical Fields on Lower Extremity Diabetic Neuropathy: A Pilot, Open-Label Study Completed NCT00614341 Phase 4
35 Efficacy of Administration of ACE-Inhibition on Autonomic and Peripheral Neuropathy in Patients With Diabetes Mellitus Completed NCT03031834 Phase 4 Quinapril
36 Study of Metanx® in Subjects With Type 2 Diabetic Peripheral Neuropathy (DPN) Completed NCT00726713 Phase 4
37 Citicoline Effect on Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) Completed NCT03046693 Phase 4 Group A Citicoline 1000 mg oral tablet;Group B placebo oral tablet
38 A New Medicine to Treat Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) Completed NCT01975324 Phase 4 dalfampridine;Placebo
39 A Study on the Efficacy and Safety of Gabapentin in the Treatment of Patients With Painful Diabetic Neuropathy Completed NCT00644748 Phase 4 gabapentin
40 A Study to Compare Safety and Efficacy of Tramadol Hydrochloride/Acetaminophen With Gabapentin in Participants With Diabetic Neuropathy Completed NCT00634543 Phase 4 Tramadol hydrochloride/ Acetaminophen;Gabapentin
41 Evaluation of the Efficacy of Cesametâ„¢ for the Treatment of Pain in Patients With Diabetic Peripheral Neuropathy Completed NCT00380913 Phase 4 Cesametâ„¢ (nabilone)
42 Pregabalin in the Treatment of Pain Due to Diabetic Peripheral Neuropathy Completed NCT00159679 Phase 4 Pregabalin
43 A Study To Evaluate Pregabalin In Patients With Painful Diabetic Peripheral Neuropathy (DPN) Completed NCT00156078 Phase 4 pregabalin
44 Anodyne Therapy in Diabetic Sensory Neuropathy Completed NCT00120341 Phase 4
45 A Study of the Efficacy and Safety of Pregabalin for the Treatment of Diabetic Peripheral Neuropathy or Postherpetic Neuralgia Completed NCT00629681 Phase 4 Pregabalin
46 Effect of Levodopa-Carbidopa on Visual Function in Patients With Recent-Onset Nonarteritic Anterior Ischemic Optic Neuropathy Completed NCT00432393 Phase 4 levodopa-carbidopa
47 Evaluation of Rocker sOles in Diabetis Completed NCT02891928 Phase 4
48 Safety of Pregabalin in the Treatment of Pain Due to Diabetic Peripheral Neuropathy Completed NCT00159731 Phase 4 Pregabalin
49 A Study of the Effectiveness And Safety Of Lidoderm® As Add-On Treatment in Patients With Postherpetic Neuralgia, Diabetic Neuropathy, or Low Back Pain Completed NCT00904020 Phase 4 Lidoderm
50 Alpha Lipoic Acid for Treatment of Diabetic Neuropathy Completed NCT02439879 Phase 4 Alpha lipoic acid

Search NIH Clinical Center for Neuropathy

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Genetic Tests for Neuropathy

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Anatomical Context for Neuropathy

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The Foundational Model of Anatomy Ontology organs/tissues related to Neuropathy:

19
Nerves Or Nerve Cells

MalaCards organs/tissues related to Neuropathy:

41
Lung, Spinal Cord, Testes, Skin, Bone, Brain, Heart
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Publications for Neuropathy

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Articles related to Neuropathy:

(show top 50) (show all 8841)
# Title Authors Year
1
Cure of human diabetic neuropathy by HPLC validated bark extract of Onosma echioides L. root. ( 29629826 )
2018
2
Hyperhomocysteinemia in bilateral anterior ischemic optic neuropathy after conventional coronary artery bypass graft: a case report. ( 29338755 )
2018
3
Different nerve ultrasound patterns in charcot-marie-tooth types and hereditary neuropathy with liability to pressure palsies. ( 28802056 )
2018
4
Pseudohemangioma in Nonarteritic Anterior Ischemic Optic Neuropathy. ( 29784095 )
2018
5
Diabetic neuropathy and painful diabetic neuropathy: Cinderella complications in South East Asia. ( 29371725 )
2018
6
Clinical and genetic features of Charcot-Marie-Tooth disease 2F and hereditary motor neuropathy 2B in Japan. ( 29381233 )
2018
7
Diffusion-Weighted Imaging Changes in a Child With Posterior Ischemic Optic Neuropathy. ( 29859720 )
2018
8
Causes of peroneal neuropathy associated with orthopaedic leg lengthening in different canine models. ( 29802558 )
2018
9
Quantitative analysis of optical coherence tomographic angiography (OCT-A) in patients with non-arteritic anterior ischemic optic neuropathy (NAION) corresponds to visual function. ( 29953490 )
2018
10
Multiple cranial neuropathies as a presentation of spontaneous internal carotid artery dissection: A case report and literature review. ( 29422362 )
2018
11
Spinobulbar muscular atrophy combined with atypical hereditary neuropathy with liability to pressure palsy. ( 29137918 )
2018
12
Genetic Testing for Wolfram Syndrome Mutations in a Sample of 71 Patients with Hereditary Optic Neuropathy and Negative Genetic Test Results for <i>OPA1/OPA3/LHON</i>. ( 29563951 )
2018
13
Could Buerger's disease cause nonarteritic anterior ischemic optic neuropathy?: a rare case report. ( 29623524 )
2018
14
Sciatic neuropathy and rhabdomyolysis after carbon monoxide intoxication: A case report. ( 29879074 )
2018
15
Safety of rAAV2/2-ND4 Gene Therapy for Leber Hereditary Optic Neuropathy. ( 29426586 )
2018
16
Analysis of Visual Field Defects Obtained with Semiautomated Kinetic Perimetry in Patients with Leber Hereditary Optic Neuropathy. ( 29750122 )
2018
17
Long-term Peripheral Neuropathy in Breast Cancer Patients Treated With Adjuvant Chemotherapy: NRG Oncology/NSABP B-30. ( 28954297 )
2018
18
Topiramate-induced Neuropathy Mimicking Carpal Tunnel Syndrome: A Case Report. ( 29430500 )
2018
19
Single fiber F-waves compared with conventional surface F-waves, and their utility in detecting early diabetic neuropathy. ( 29975798 )
2018
20
Longterm Reversal of Severe Visual Loss by Mitochondrial Gene Transfer in a Mouse Model of Leber Hereditary Optic Neuropathy. ( 29615737 )
2018
21
Insights into the Contribution of Voltage-Gated Sodium Channel 1.7 to Paclitaxel-Induced Neuropathy. ( 29973416 )
2018
22
The first case of hourglass-like constriction neuropathy of a digital nerve. ( 29449158 )
2018
23
Altered TDP-43-dependent splicing in HSPB8-related distal hereditary motor neuropathy and myofibrillar myopathy. ( 29029362 )
2018
24
Late-onset Leber hereditary optic neuropathy presenting after intraocular surgery. ( 29784175 )
2018
25
Chemotherapy-Associated Peripheral Neuropathy in Patients With Early-Stage Breast Cancer: A Systematic Review. ( 28954296 )
2018
26
Evaluation of Dizziness Handicap in Adolescents and Adults with Auditory Neuropathy Spectrum Disorder. ( 29371893 )
2018
27
Neuroprotective effect of duloxetine in a mouse model of diabetic neuropathy: Role of glia suppressing mechanisms. ( 29763613 )
2018
28
The CAPOS mutation in ATP1A3 alters Na/K-ATPase function and results in auditory neuropathy which has implications for management. ( 29305691 )
2018
29
Optic neuropathy and congenital glaucoma associated with probable Zika virus infection in Venezuelan patients. ( 29896405 )
2018
30
Wernicke-Korsakoff syndrome complicated by subacute beriberi neuropathy in an alcoholic patient. ( 29128624 )
2018
31
A patient with peripheral demyelinating neuropathy, central dysmyelinating leukodystrophy, Waardenburg syndrome, and severe hypoganglionosis associated with a novel SOX10 mutation. ( 29681101 )
2018
32
Comparison of peripheral nerve blockade characteristics between non-diabetic patients and patients suffering from diabetic neuropathy: a prospective cohort study. ( 29858510 )
2018
33
Incidence and disease burden of chemotherapy-induced peripheral neuropathy in a population-based cohort. ( 29439162 )
2018
34
Adenosine monophosphate-activated protein kinase modulation by berberine attenuates mitochondrial deficits and redox imbalance in experimental diabetic neuropathy. ( 29273519 )
2018
35
Cardiovascular Autonomic Neuropathy and Glucose Variability in Patients With Type 1 Diabetes: Is There an Association? ( 29725320 )
2018
36
Ulnar neuropathy at wrist: entrapment at a very &amp;quot;congested&amp;quot; site. ( 29779137 )
2018
37
Cerebral Biochemical Effect of Pregabalin in Patients with Painful Diabetic Neuropathy: A Randomized Controlled Trial. ( 29951977 )
2018
38
Optimal Measurement Level and Ulnar Nerve Cross-Sectional Area Cutoff Threshold for Identifying Ulnar Neuropathy at the Elbow by MRI and Ultrasonography. ( 29622409 )
2018
39
Feasibility Trial of Treatment of Ulnar Neuropathy at the Elbow Using a Specifically Designed Splint. ( 29912777 )
2018
40
Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation. ( 29981335 )
2018
41
Feasibility and effectiveness of electrochemical dermal conductance measurement for the screening of diabetic neuropathy in primary care. DECODING Study (Dermal Electrochemical Conductance in Diabetic Neuropathy). Rationale and design. ( 29768354 )
2018
42
Ischemic Optic Neuropathy in a Dog with Acute Bilateral Blindness and Primary Systemic Hypertension. ( 29130572 )
2018
43
Mutations in COA7 cause spinocerebellar ataxia with axonal neuropathy. ( 29718187 )
2018
44
Hearing Loss in Type 2 Diabetes in Association with Diabetic Neuropathy. ( 29433858 )
2018
45
Comparison of Ultrasonography and Short-Segment Nerve Conduction Study in Ulnar Neuropathy at the Elbow. ( 28987902 )
2018
46
Optical coherence tomography angiography changes in radial peripapillary capillaries in Leber hereditary optic neuropathy. ( 29468220 )
2018
47
Shear-wave elastography: a new potential method to diagnose ulnar neuropathy at the elbow. ( 29858636 )
2018
48
An Unforeseeable Complication; Posterior Ischemic Optic Neuropathy after Penetrating Injury to the Heart. ( 29719851 )
2018
49
Retinal and Choroidal Microvasculature in Nonarteritic Anterior Ischemic Optic Neuropathy: An Optical Coherence Tomography Angiography Study. ( 29490340 )
2018
50
Repeated hyperhidrosis and chilblain-like swelling with ulceration of the fingers and toes in hereditary sensory and autonomic neuropathy type II. ( 29701257 )
2018
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Variations for Neuropathy

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Copy number variations for Neuropathy from CNVD:

7
# CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 107544 17 15900000 22100000 Microdeletion Neuropathy
2 107574 17 16000000 22200000 Copy number Neuropathy
3 216423 6 92100000 98700000 Microdeletion EPHA7 Neuropathy
Sources

Expression for Neuropathy

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Search GEO for disease gene expression data for Neuropathy.
Sources

Pathways for Neuropathy

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Pathways related to Neuropathy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Neural Crest Differentiation 1
10.81 GJB1 MPZ PMP22