MCID: NRS001
MIFTS: 28

Neuroschistosomiasis

Categories: Infectious diseases, Nephrological diseases, Neuronal diseases

Aliases & Classifications for Neuroschistosomiasis

MalaCards integrated aliases for Neuroschistosomiasis:

Name: Neuroschistosomiasis 12 45 15 17 74

Classifications:



External Ids:

Disease Ontology 12 DOID:13722
MeSH 45 D020818
UMLS 74 C0752191

Summaries for Neuroschistosomiasis

Disease Ontology : 12 A schistosomiasis that involves parasitic infection of the brain and spinal cord by Schistosoma haematobium, Schistosoma mansoni or Schistosoma japonicum causing acute or subacute myelopathy, focal central nervous system impairment, seizures and increased intracranial pressure.

MalaCards based summary : Neuroschistosomiasis is related to vasculitis and encephalitis. An important gene associated with Neuroschistosomiasis is NGF (Nerve Growth Factor), and among its related pathways/superpathways are Immune response IFN gamma signaling pathway and Immune response IFN alpha/beta signaling pathway. Affiliated tissues include spinal cord, brain and kidney, and related phenotypes are integument and normal

Wikipedia : 77 Schistosomiasis, also known as snail fever and bilharzia, is a disease caused by parasitic flatworms... more...

Related Diseases for Neuroschistosomiasis

Diseases related to Neuroschistosomiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 18)
# Related Disease Score Top Affiliating Genes
1 vasculitis 10.2
2 encephalitis 10.1
3 foot drop 10.1
4 nervous system disease 9.9 IFNG NGF
5 keratoconjunctivitis 9.9 IFNG NGF
6 prurigo nodularis 9.8 NGF TAC1
7 burning mouth syndrome 9.8 NGF TAC1
8 autonomic nervous system disease 9.8 NGF TAC1
9 paine syndrome 9.8 NGF TAC1
10 causalgia 9.8 NGF TAC1
11 somatoform disorder 9.7 NGF TAC1
12 upper respiratory tract disease 9.7 IFNG TAC1
13 interstitial cystitis 9.7 NGF TAC1
14 allergic rhinitis 9.7 IFNG NGF
15 cystitis 9.7 NGF TAC1
16 peripheral nervous system disease 9.6 NGF TAC1
17 central nervous system disease 9.6 IFNG NGF
18 asthma 9.3 IFNG NGF TAC1

Graphical network of the top 20 diseases related to Neuroschistosomiasis:



Diseases related to Neuroschistosomiasis

Symptoms & Phenotypes for Neuroschistosomiasis

MGI Mouse Phenotypes related to Neuroschistosomiasis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.13 IFNG NGF TAC1
2 normal MP:0002873 8.8 IFNG NGF TAC1

Drugs & Therapeutics for Neuroschistosomiasis

Search Clinical Trials , NIH Clinical Center for Neuroschistosomiasis

Cochrane evidence based reviews: neuroschistosomiasis

Genetic Tests for Neuroschistosomiasis

Anatomical Context for Neuroschistosomiasis

MalaCards organs/tissues related to Neuroschistosomiasis:

42
Spinal Cord, Brain, Kidney, Liver, Testes

Publications for Neuroschistosomiasis

Articles related to Neuroschistosomiasis:

(show all 34)
# Title Authors Year
1
Prevalence of urodynamic changes with risk for upper urinary tract damage in neuroschistosomiasis patients. ( 30652786 )
2019
2
Pediatric Neuroschistosomiasis: A Case Report and Review of the Literature. ( 30840073 )
2019
3
Neuroschistosomiasis mimicking lower back pain: case report of a rare differential diagnosis in a pediatric patient. ( 30323860 )
2018
4
Neuroschistosomiasis: An Unusual Intracranial Space Occupying Lesion. ( 30587650 )
2018
5
Spinal neuroschistosomiasis. ( 25891496 )
2015
6
Myeloradicular Form of Neuroschistosomiasis in a Six-Year-Old Boy Infected With Schistosoma mansoni. ( 26780026 )
2015
7
Diagnosis of neuroschistosomiasis by indicative antibody specificity index and comparative semiquantitative real-time PCR from cerebrospinal fluid and serum. ( 24227876 )
2013
8
Mansonic neuroschistosomiasis. ( 24141511 )
2013
9
Pseudotumoral form of neuroschistosomiasis: report of three cases in Ganzi, China. ( 22302862 )
2012
10
Neuroschistosomiasis. ( 21674195 )
2012
11
Neuroschistosomiasis mansoni: literature review and guidelines. ( 23114664 )
2012
12
Neuroschistosomiasis due to Schistosoma haematobium presenting as spinal cord tumor. ( 21734619 )
2011
13
Neuroschistosomiasis: clinical symptoms and pathogenesis. ( 21849166 )
2011
14
Neuroschistosomiasis. ( 21073294 )
2010
15
A laboratory test for the diagnosis of neuroschistosomiasis. ( 20406603 )
2010
16
A bilateral foot drop due to neuroschistosomiasis. ( 20127348 )
2010
17
Acute neuroschistosomiasis: a cerebral vasculitis to treat with corticosteroids not praziquantel. ( 20920061 )
2010
18
Two patients with imported acute neuroschistosomiasis due to Schistosoma mansoni. ( 20636603 )
2010
19
Epidemiological aspects in neuroschistosomiasis. ( 20339657 )
2010
20
Research development of the pathogenesis pathways for neuroschistosomiasis. ( 20332823 )
2010
21
Cerebral neuroschistosomiasis: a rare clinical presentation and review of the literature. ( 21852999 )
2009
22
Clinical characterization of neuroschistosomiasis due to Schistosoma mansoni and its treatment. ( 18499080 )
2008
23
Immune response and pathogenesis of neuroschistosomiasis mansoni. ( 18547533 )
2008
24
Neuroschistosomiasis presenting as brainstem encephalitis. ( 18519877 )
2008
25
Pseudotumoral form of neuroschistosomiasis: report of three cases. ( 17874001 )
2007
26
Acute neuroschistosomiasis: two cases associated with cerebral vasculitis. ( 17488923 )
2007
27
Early neuroschistosomiasis complicating Katayama syndrome. ( 17073109 )
2006
28
An unusually late presentation of neuroschistosomiasis. ( 16442162 )
2006
29
Neuroschistosomiasis due to Schistosoma mansoni: a review of pathogenesis, clinical syndromes and diagnostic approaches. ( 16138195 )
2005
30
Clinical and cerebrospinal fluid findings in patients less than 20 years old with a presumptive diagnosis of neuroschistosomiasis. ( 15088799 )
2004
31
Experimental neuroschistosomiasis: inadequacy of the murine model. ( 12118299 )
2002
32
Neuroschistosomiasis. ( 9034571 )
1997
33
Neuroschistosomiasis myelopathy: case report. ( 7917101 )
1994
34
Early chemotherapy of imported neuroschistosomiasis. ( 8096291 )
1993

Variations for Neuroschistosomiasis

Expression for Neuroschistosomiasis

Search GEO for disease gene expression data for Neuroschistosomiasis.

Pathways for Neuroschistosomiasis

Pathways related to Neuroschistosomiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.17 IFNG NGF
2
Show member pathways
11.17 IFNG NGF
3 10.84 NGF TAC1

GO Terms for Neuroschistosomiasis

Cellular components related to Neuroschistosomiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.33 IFNG NGF TAC1
2 axon GO:0030424 8.96 NGF TAC1
3 extracellular space GO:0005615 8.8 IFNG NGF TAC1

Biological processes related to Neuroschistosomiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.16 IFNG NGF
2 positive regulation of gene expression GO:0010628 8.96 IFNG NGF
3 positive regulation of epithelial cell migration GO:0010634 8.62 IFNG TAC1

Molecular functions related to Neuroschistosomiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 8.32 NGF

Sources for Neuroschistosomiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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