MCID: NRS001
MIFTS: 28

Neuroschistosomiasis

Categories: Infectious diseases, Nephrological diseases, Neuronal diseases

Aliases & Classifications for Neuroschistosomiasis

MalaCards integrated aliases for Neuroschistosomiasis:

Name: Neuroschistosomiasis 12 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:13722
MeSH 44 D020818
UMLS 73 C0752191

Summaries for Neuroschistosomiasis

Disease Ontology : 12 A schistosomiasis that involves parasitic infection of the brain and spinal cord by Schistosoma haematobium, Schistosoma mansoni or Schistosoma japonicum causing acute or subacute myelopathy, focal central nervous system impairment, seizures and increased intracranial pressure.

MalaCards based summary : Neuroschistosomiasis is related to vasculitis and encephalitis. An important gene associated with Neuroschistosomiasis is NGF (Nerve Growth Factor), and among its related pathways/superpathways are Immune response IFN gamma signaling pathway and Immune response IFN alpha/beta signaling pathway. Affiliated tissues include spinal cord, brain and kidney, and related phenotypes are integument and normal

Wikipedia : 76 Schistosomiasis, also known as snail fever and bilharzia, is a disease caused by parasitic flatworms... more...

Related Diseases for Neuroschistosomiasis

Diseases related to Neuroschistosomiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 20)
# Related Disease Score Top Affiliating Genes
1 vasculitis 10.2
2 encephalitis 10.1
3 foot drop 10.1
4 nervous system disease 10.0 IFNG NGF
5 keratoconjunctivitis 9.9 IFNG NGF
6 allergic rhinitis 9.9 IFNG NGF
7 prurigo nodularis 9.9 NGF TAC1
8 burning mouth syndrome 9.9 NGF TAC1
9 autonomic nervous system disease 9.9 NGF TAC1
10 central nervous system disease 9.9 IFNG NGF
11 paine syndrome 9.9 NGF TAC1
12 upper respiratory tract disease 9.9 IFNG TAC1
13 causalgia 9.9 NGF TAC1
14 somatoform disorder 9.8 NGF TAC1
15 interstitial cystitis 9.8 NGF TAC1
16 cystitis 9.8 NGF TAC1
17 dermatitis, atopic 9.8 IFNG NGF
18 peripheral nervous system disease 9.8 NGF TAC1
19 multiple sclerosis 9.8 IFNG NGF
20 asthma 9.6 IFNG NGF TAC1

Graphical network of the top 20 diseases related to Neuroschistosomiasis:



Diseases related to Neuroschistosomiasis

Symptoms & Phenotypes for Neuroschistosomiasis

MGI Mouse Phenotypes related to Neuroschistosomiasis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.13 IFNG NGF TAC1
2 normal MP:0002873 8.8 IFNG NGF TAC1

Drugs & Therapeutics for Neuroschistosomiasis

Search Clinical Trials , NIH Clinical Center for Neuroschistosomiasis

Cochrane evidence based reviews: neuroschistosomiasis

Genetic Tests for Neuroschistosomiasis

Anatomical Context for Neuroschistosomiasis

MalaCards organs/tissues related to Neuroschistosomiasis:

41
Spinal Cord, Brain, Kidney, Liver, Testes

Publications for Neuroschistosomiasis

Articles related to Neuroschistosomiasis:

(show all 31)
# Title Authors Year
1
Neuroschistosomiasis mimicking lower back pain: case report of a rare differential diagnosis in a pediatric patient. ( 30323860 )
2018
2
Spinal neuroschistosomiasis. ( 25891496 )
2015
3
Myeloradicular Form of Neuroschistosomiasis in a Six-Year-Old Boy Infected With Schistosoma mansoni. ( 26780026 )
2015
4
Diagnosis of neuroschistosomiasis by indicative antibody specificity index and comparative semiquantitative real-time PCR from cerebrospinal fluid and serum. ( 24227876 )
2013
5
Mansonic neuroschistosomiasis. ( 24141511 )
2013
6
Pseudotumoral form of neuroschistosomiasis: report of three cases in Ganzi, China. ( 22302862 )
2012
7
Neuroschistosomiasis. ( 21674195 )
2012
8
Neuroschistosomiasis mansoni: literature review and guidelines. ( 23114664 )
2012
9
Neuroschistosomiasis due to Schistosoma haematobium presenting as spinal cord tumor. ( 21734619 )
2011
10
Neuroschistosomiasis: clinical symptoms and pathogenesis. ( 21849166 )
2011
11
Neuroschistosomiasis. ( 21073294 )
2010
12
A laboratory test for the diagnosis of neuroschistosomiasis. ( 20406603 )
2010
13
A bilateral foot drop due to neuroschistosomiasis. ( 20127348 )
2010
14
Acute neuroschistosomiasis: a cerebral vasculitis to treat with corticosteroids not praziquantel. ( 20920061 )
2010
15
Two patients with imported acute neuroschistosomiasis due to Schistosoma mansoni. ( 20636603 )
2010
16
Epidemiological aspects in neuroschistosomiasis. ( 20339657 )
2010
17
Research development of the pathogenesis pathways for neuroschistosomiasis. ( 20332823 )
2010
18
Cerebral neuroschistosomiasis: a rare clinical presentation and review of the literature. ( 21852999 )
2009
19
Clinical characterization of neuroschistosomiasis due to Schistosoma mansoni and its treatment. ( 18499080 )
2008
20
Immune response and pathogenesis of neuroschistosomiasis mansoni. ( 18547533 )
2008
21
Neuroschistosomiasis presenting as brainstem encephalitis. ( 18519877 )
2008
22
Pseudotumoral form of neuroschistosomiasis: report of three cases. ( 17874001 )
2007
23
Acute neuroschistosomiasis: two cases associated with cerebral vasculitis. ( 17488923 )
2007
24
Early neuroschistosomiasis complicating Katayama syndrome. ( 17073109 )
2006
25
An unusually late presentation of neuroschistosomiasis. ( 16442162 )
2006
26
Neuroschistosomiasis due to Schistosoma mansoni: a review of pathogenesis, clinical syndromes and diagnostic approaches. ( 16138195 )
2005
27
Clinical and cerebrospinal fluid findings in patients less than 20 years old with a presumptive diagnosis of neuroschistosomiasis. ( 15088799 )
2004
28
Experimental neuroschistosomiasis: inadequacy of the murine model. ( 12118299 )
2002
29
Neuroschistosomiasis. ( 9034571 )
1997
30
Neuroschistosomiasis myelopathy: case report. ( 7917101 )
1994
31
Early chemotherapy of imported neuroschistosomiasis. ( 8096291 )
1993

Variations for Neuroschistosomiasis

Expression for Neuroschistosomiasis

Search GEO for disease gene expression data for Neuroschistosomiasis.

Pathways for Neuroschistosomiasis

Pathways related to Neuroschistosomiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.17 IFNG NGF
2
Show member pathways
11.17 IFNG NGF
3 10.84 NGF TAC1

GO Terms for Neuroschistosomiasis

Cellular components related to Neuroschistosomiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.33 IFNG NGF TAC1
2 axon GO:0030424 8.96 NGF TAC1
3 extracellular space GO:0005615 8.8 IFNG NGF TAC1

Biological processes related to Neuroschistosomiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.16 IFNG NGF
2 positive regulation of gene expression GO:0010628 8.96 IFNG NGF
3 positive regulation of epithelial cell migration GO:0010634 8.62 IFNG TAC1

Molecular functions related to Neuroschistosomiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 8.62 NGF TAC1

Sources for Neuroschistosomiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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