MCID: NTR042
MIFTS: 34

Neutrophilic Dermatosis, Acute Febrile

Categories: Bone diseases, Rare diseases, Skin diseases

Aliases & Classifications for Neutrophilic Dermatosis, Acute Febrile

MalaCards integrated aliases for Neutrophilic Dermatosis, Acute Febrile:

Name: Neutrophilic Dermatosis, Acute Febrile 58 54
Sweet Syndrome 58 77 54 60 74
Acute Febrile Neutrophilic Dermatosis 77 54 60
Ss 58 54
Acromelic Frontonasal Dysostosis 74
Gomm-Button Disease 58
Gomm Button Disease 54
Sweet Syndrome; Ss 58
Sweets Syndrome 56
Afnd 58

Characteristics:

Orphanet epidemiological data:

60
sweet syndrome
Prevalence: <1/1000000 (Worldwide); Age of onset: Adult;

Classifications:



External Ids:

OMIM 58 608068
MESH via Orphanet 46 D016463
ICD10 via Orphanet 35 L98.2
UMLS via Orphanet 75 C0085077
Orphanet 60 ORPHA3243
MedGen 43 C0085077

Summaries for Neutrophilic Dermatosis, Acute Febrile

NIH Rare Diseases : 54 Acute febrile neutrophilic dermatosis is a skin condition characterized by fever, inflammation of the joints (arthritis), and painful skin lesions that appear mainly on the face, neck, back and arms. Although middle-aged women are most likely to develop this condition, it may also affect men, older adults and even infants. The exact cause of acute febrile neutrophilic dermatosis often isn't known. It is suspected that it can be a reaction of the body to certain exposures (sun), infections (Streptococcus bacteria, Campylobacter), or medications (azathioprine, nonsteroidal anti-inflammatory medications). This condition can also occur with some types of cancer and other serious health problems. Most often, it isn't serious and will clear on its own in a few months. Healing is much more rapid; however, with treatment, such as corticosteroid use.

MalaCards based summary : Neutrophilic Dermatosis, Acute Febrile, also known as sweet syndrome, is related to acromelic frontonasal dysostosis and sickle cell anemia, and has symptoms including seizures An important gene associated with Neutrophilic Dermatosis, Acute Febrile is CSF3 (Colony Stimulating Factor 3). Affiliated tissues include neutrophil, skin and myeloid.

Wikipedia : 77 Sweet''s syndrome (SS), or acute febrile neutrophilic dermatosis is a skin disease characterized by the... more...

Description from OMIM: 608068

Related Diseases for Neutrophilic Dermatosis, Acute Febrile

Diseases related to Neutrophilic Dermatosis, Acute Febrile via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 293)
# Related Disease Score Top Affiliating Genes
1 acromelic frontonasal dysostosis 12.0
2 sickle cell anemia 11.9
3 majeed syndrome 11.6
4 hemoglobin se disease 11.3
5 frontonasal dysplasia 1 11.1
6 schimmelpenning-feuerstein-mims syndrome 11.1
7 fetal hemoglobin quantitative trait locus 5 11.1
8 serotonin syndrome 11.1
9 atrial standstill 1 10.5
10 leukemia 10.4
11 heart block, congenital 10.4
12 blood group, junior system 10.3
13 adenocarcinoma 10.3
14 myelodysplastic syndrome 10.3
15 annular erythema 10.2
16 disorganization, mouse, homolog of 10.2
17 lupus erythematosus 10.2
18 connective tissue disease 10.2
19 sickle cell disease 10.2
20 vasculitis 10.1
21 sarcoma 10.1
22 suppression of tumorigenicity 12 10.1
23 myocardial infarction 10.1
24 dressler's syndrome 10.1
25 anterior scleritis 10.1
26 polyneuropathy 10.1
27 essential thrombocythemia 10.1
28 transitional cell carcinoma 10.1
29 bone marrow cancer 10.1
30 nodular episcleritis 10.1
31 influenza 10.1
32 enteropathy-associated t-cell lymphoma 10.1
33 rheumatoid vasculitis 10.1
34 bullous pyoderma gangrenosum 10.1
35 systemic lupus erythematosus 10.1
36 myeloid leukemia 10.1
37 sarcoma, synovial 10.0
38 premature ejaculation 10.0
39 polymyositis 10.0
40 cellulitis 10.0
41 alpha-thalassemia 10.0
42 thalassemia 10.0
43 atrioventricular block 10.0
44 hemoglobinopathy 10.0
45 myeloma, multiple 10.0
46 leukemia, chronic myeloid 10.0
47 crohn's disease 10.0
48 melanoma 10.0
49 hairy cell leukemia 10.0
50 bladder cancer 9.9

Graphical network of the top 20 diseases related to Neutrophilic Dermatosis, Acute Febrile:



Diseases related to Neutrophilic Dermatosis, Acute Febrile

Symptoms & Phenotypes for Neutrophilic Dermatosis, Acute Febrile

Clinical features from OMIM:

608068

UMLS symptoms related to Neutrophilic Dermatosis, Acute Febrile:


seizures

Drugs & Therapeutics for Neutrophilic Dermatosis, Acute Febrile

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Observational Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases Recruiting NCT01952275

Search NIH Clinical Center for Neutrophilic Dermatosis, Acute Febrile

Genetic Tests for Neutrophilic Dermatosis, Acute Febrile

Anatomical Context for Neutrophilic Dermatosis, Acute Febrile

MalaCards organs/tissues related to Neutrophilic Dermatosis, Acute Febrile:

42
Neutrophil, Skin, Myeloid, T Cells, Bone, Thyroid, Prostate

Publications for Neutrophilic Dermatosis, Acute Febrile

Articles related to Neutrophilic Dermatosis, Acute Febrile:

(show top 50) (show all 293)
# Title Authors Year
1
Sweet syndrome induced by radiations during breast cancer treatment. ( 30940664 )
2019
2
Giant cellulitis-like Sweet syndrome as an initial clinical presentation of acute myeloblastic leukemia with t(6;9)(p23;q34): DEK-CAN and internal duplications of FMS-like tyrosine kinase 3. ( 30659317 )
2019
3
Sweet syndrome in association with enterobiasis. ( 30187540 )
2019
4
Sweet syndrome in a patient with chronic myelogenous leukemia under dasatinib treatment. ( 30932238 )
2019
5
Sweet syndrome in metastatic melanoma during treatment with dabrafenib and trametinib. ( 30724336 )
2019
6
Sweet syndrome following a positive Mantoux test due to pulmonary tuberculosis. ( 30238576 )
2019
7
Expanding the differential diagnosis of raccoon eyes: sweet syndrome. ( 29852061 )
2019
8
Image Gallery: Hairy-cell leukaemia presenting with Sweet syndrome. ( 30194758 )
2019
9
Histiocytoid Sweet syndrome harboring an isocitrate dehydrogenase 1 mutation: A case report and retrospective analysis of 29 cases of histiocytoid Sweet syndrome. ( 30632174 )
2019
10
Sweet syndrome with pseudocarcinomatous hyperplasia: A case report and review of the literature. ( 30734344 )
2019
11
Sweet syndrome in acute myeloid leukaemia. ( 30788846 )
2019
12
Proliferative Sweet syndrome associated with pregnancy and low-molecular-weight heparin sodium. ( 30907689 )
2019
13
Sweet syndrome: a rare feature of ANCA-associated vasculitis or unusual consequence of azathioprine-induced treatment. ( 30455717 )
2018
14
Aseptic meningitis and anti-β2-glycoprotein 1 antibodies in Sweet syndrome. ( 27452622 )
2018
15
Sweet syndrome after treatment with vedolizumab in a patient with Crohn's disease. ( 29900741 )
2018
16
Neutrophilic dermatoses: Pathogenesis, Sweet syndrome, neutrophilic eccrine hidradenitis, and Behçet disease. ( 29653210 )
2018
17
Neonatal lupus erythematosus or Sweet syndrome? ( 30246125 )
2018
18
Sweet Syndrome in a Patient With Systemic Lupus Erythematosus. ( 30247226 )
2018
19
Pyoderma gangrenosum and Sweet syndrome: the prototypic neutrophilic dermatoses. ( 26202386 )
2018
20
Drug-Induced Sweet Syndrome in a Man With Sarcoidosis: Are There Any Common Mechanisms of Pathogenesis? ( 29538086 )
2018
21
Subcutaneous Histiocytoid Sweet Syndrome in a Patient With Relapsed Acute Myeloblastic Leukemia. ( 28291132 )
2018
22
Sweet syndrome presenting as a febrile rash in a returning traveller. ( 28534449 )
2018
23
Necrotizing Sweet Syndrome of the Upper Extremity After Elective Hand Surgery. ( 28935337 )
2018
24
Sweet syndrome caused by sensitization to gabapentin. ( 28958741 )
2018
25
Azacitidine-induced Sweet syndrome: Two unusual clinical presentations. ( 29044459 )
2018
26
Sweet syndrome in patients with and without malignancy: A retrospective analysis of 83 patients from a tertiary academic referral center. ( 29107342 )
2018
27
Lymphocytes in Sweet syndrome: A potential diagnostic pitfall. ( 29265393 )
2018
28
Potassium iodide in refractory, recurrent pediatric Sweet syndrome: Guidance in dosing and monitoring. ( 29314271 )
2018
29
Sweet syndrome associated with ipilimumab in a patient with metastatic melanoma. ( 29396853 )
2018
30
Sweet syndrome as the leading symptom in the diagnosis of gastric cancer. ( 29486570 )
2018
31
Sweet syndrome with aseptic splenic abscesses and multiple myeloma. ( 29894540 )
2018
32
Histiocytoid Sweet syndrome successfully treated with etanercept. ( 29904308 )
2018
33
Copresentation of common variable immune deficiency and Sweet syndrome. ( 30063785 )
2018
34
Azathioprine-Induced Sweet Syndrome Treated With Infliximab. ( 30074533 )
2018
35
Idiopathic histiocytoid Sweet syndrome: a case report with clinical and histopathological considerations. ( 30113066 )
2018
36
Bullous sweet syndrome healing with prominent secondary anetoderma. ( 30152553 )
2018
37
Sweet Syndrome in Pediatrics. A case report. ( 30571826 )
2018
38
Superficial and Deep Cutaneous Involvement by RAS-Associated Autoimmunne Leukoproliferative Disease (RALD Cutis): A Histologic Mimicker of Histiocytoid Sweet Syndrome. ( 30601210 )
2018
39
Sweet Syndrome After Bilateral Deep Inferior Epigastric Perforator Flap Breast Reconstruction: A Case Report. ( 28604546 )
2017
40
Sweet syndrome secondary to myelodysplastic syndrome mimicking necrotizing fasciitis. ( 28589451 )
2017
41
Necrotizing Sweet syndrome in a patient with myelodysplastic syndrome. ( 28422309 )
2017
42
Histiocytoid Sweet Syndrome and Myelodysplastic Syndrome. ( 28614548 )
2017
43
Histiocytoid Sweet Syndrome and Myelodysplastic Syndrome-Reply. ( 28614552 )
2017
44
Necrotizing Soft Tissue Infection or Sweet Syndrome: Surgery Versus No Surgery?: A Case Report. ( 28151765 )
2017
45
A rare case report describing the relation between sweet syndrome and spontaneous recurrent peritonitis. ( 28957773 )
2017
46
Sweet Syndrome Associated with Bilateral Nodular Scleritis. ( 29282197 )
2017
47
Histiocytoid Sweet syndrome with ophthalmologic involvements: A novel association with uveitis. ( 27177942 )
2017
48
Clinicopathologic, immunophenotyping and cytogenetic analysis of Sweet syndrome in Egyptian patients with acute myeloid leukemia. ( 28024959 )
2017
49
Acute Myeloid Leukemia Presenting with Sweet Syndrome: A Case Report and Review of the Literature. ( 27720691 )
2017
50
Ticagrelor-induced Sweet Syndrome: an unusual dermatologic complication after percutaneous coronary intervention. ( 27146134 )
2017

Variations for Neutrophilic Dermatosis, Acute Febrile

Expression for Neutrophilic Dermatosis, Acute Febrile

Search GEO for disease gene expression data for Neutrophilic Dermatosis, Acute Febrile.

Pathways for Neutrophilic Dermatosis, Acute Febrile

GO Terms for Neutrophilic Dermatosis, Acute Febrile

Sources for Neutrophilic Dermatosis, Acute Febrile

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75 UMLS via Orphanet
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