SS
MCID: NTR042
MIFTS: 36

Neutrophilic Dermatosis, Acute Febrile (SS)

Categories: Bone diseases, Rare diseases, Skin diseases

Aliases & Classifications for Neutrophilic Dermatosis, Acute Febrile

MalaCards integrated aliases for Neutrophilic Dermatosis, Acute Febrile:

Name: Neutrophilic Dermatosis, Acute Febrile 57 53
Sweet Syndrome 57 76 53 59 73
Acute Febrile Neutrophilic Dermatosis 76 53 59
Ss 57 53
Acromelic Frontonasal Dysostosis 73
Gomm-Button Disease 57
Gomm Button Disease 53
Sweet Syndrome; Ss 57
Sweets Syndrome 55
Afnd 57

Characteristics:

Orphanet epidemiological data:

59
sweet syndrome
Prevalence: <1/1000000 (Worldwide); Age of onset: Adult;

Classifications:



External Ids:

OMIM 57 608068
Orphanet 59 ORPHA3243
ICD10 via Orphanet 34 L98.2
MESH via Orphanet 45 D016463
UMLS via Orphanet 74 C0085077
MedGen 42 C0085077

Summaries for Neutrophilic Dermatosis, Acute Febrile

NIH Rare Diseases : 53 Acute febrile neutrophilic dermatosis is a skin condition characterized by fever, inflammation of the joints (arthritis), and painful skin lesions that appear mainly on the face, neck, back and arms. Although middle-aged women are most likely to develop this condition, it may also affect men, older adults and even infants. The exact cause of acute febrile neutrophilic dermatosis often isn't known. It is suspected that it can be a reaction of the body to certain exposures (sun), infections (Streptococcus bacteria, Campylobacter), or medications (azathioprine, nonsteroidal anti-inflammatory medications). This condition can also occur with some types of cancer and other serious health problems. Most often, it isn't serious and will clear on its own in a few months. Healing is much more rapid; however, with treatment, such as corticosteroid use.

MalaCards based summary : Neutrophilic Dermatosis, Acute Febrile, also known as sweet syndrome, is related to acromelic frontonasal dysostosis and sickle cell anemia, and has symptoms including seizures An important gene associated with Neutrophilic Dermatosis, Acute Febrile is CSF3 (Colony Stimulating Factor 3). Affiliated tissues include neutrophil, skin and myeloid.

Wikipedia : 76 Sweet''s syndrome (SS), or acute febrile neutrophilic dermatosis is a skin disease characterized by the... more...

Description from OMIM: 608068

Related Diseases for Neutrophilic Dermatosis, Acute Febrile

Diseases related to Neutrophilic Dermatosis, Acute Febrile via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 235)
# Related Disease Score Top Affiliating Genes
1 acromelic frontonasal dysostosis 12.0
2 sickle cell anemia 11.7
3 sjogren syndrome 11.4
4 majeed syndrome 11.2
5 hemoglobin se disease 11.2
6 frontonasal dysplasia 1 11.1
7 schimmelpenning-feuerstein-mims syndrome 11.1
8 fetal hemoglobin quantitative trait locus 5 11.0
9 serotonin syndrome 11.0
10 atrial standstill 1 10.4
11 heart block, congenital 10.4
12 adenocarcinoma 10.3
13 leukemia 10.2
14 annular erythema 10.2
15 disorganization, mouse, homolog of 10.2
16 myelodysplastic syndrome 10.2
17 connective tissue disease 10.2
18 sickle cell disease 10.1
19 lupus erythematosus 10.1
20 vasculitis 10.1
21 sarcoma 10.1
22 sarcoma, synovial 10.0
23 premature ejaculation 10.0
24 suppression of tumorigenicity 12 10.0
25 myocardial infarction 10.0
26 dressler's syndrome 10.0
27 anterior scleritis 10.0
28 polyneuropathy 10.0
29 essential thrombocythemia 10.0
30 transitional cell carcinoma 10.0
31 nodular episcleritis 10.0
32 influenza 10.0
33 enteropathy-associated t-cell lymphoma 10.0
34 rheumatoid vasculitis 10.0
35 systemic lupus erythematosus 10.0
36 myeloid leukemia 10.0
37 alpha-thalassemia 10.0
38 thalassemia 10.0
39 hemoglobinopathy 10.0
40 myeloma, multiple 9.9
41 crohn's disease 9.9
42 hairy cell leukemia 9.9
43 cellulitis 9.9
44 prostate cancer 9.9
45 neuromyelitis optica 9.9
46 pemphigus foliaceus 9.9
47 dermatomyositis 9.9
48 open-angle glaucoma 9.9
49 polymyositis 9.9
50 primary sjögren syndrome 9.9

Graphical network of the top 20 diseases related to Neutrophilic Dermatosis, Acute Febrile:



Diseases related to Neutrophilic Dermatosis, Acute Febrile

Symptoms & Phenotypes for Neutrophilic Dermatosis, Acute Febrile

Clinical features from OMIM:

608068

UMLS symptoms related to Neutrophilic Dermatosis, Acute Febrile:


seizures

Drugs & Therapeutics for Neutrophilic Dermatosis, Acute Febrile

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Observational Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases Recruiting NCT01952275

Search NIH Clinical Center for Neutrophilic Dermatosis, Acute Febrile

Genetic Tests for Neutrophilic Dermatosis, Acute Febrile

Anatomical Context for Neutrophilic Dermatosis, Acute Febrile

MalaCards organs/tissues related to Neutrophilic Dermatosis, Acute Febrile:

41
Neutrophil, Skin, Myeloid, Bone, Lung, T Cells, B Cells

Publications for Neutrophilic Dermatosis, Acute Febrile

Articles related to Neutrophilic Dermatosis, Acute Febrile:

(show top 50) (show all 283)
# Title Authors Year
1
Sweet syndrome in patients with and without malignancy: A retrospective analysis of 83 patients from a tertiary academic referral center. ( 29107342 )
2018
2
Sweet syndrome: a rare feature of ANCA-associated vasculitis or unusual consequence of azathioprine-induced treatment. ( 30455717 )
2018
3
Sweet syndrome after treatment with vedolizumab in a patient with Crohn's disease. ( 29900741 )
2018
4
Sweet syndrome in association with enterobiasis. ( 30187540 )
2018
5
Neutrophilic dermatoses: Pathogenesis, Sweet syndrome, neutrophilic eccrine hidradenitis, and Behçet disease. ( 29653210 )
2018
6
Neonatal lupus erythematosus or Sweet syndrome? ( 30246125 )
2018
7
Sweet Syndrome in a Patient With Systemic Lupus Erythematosus. ( 30247226 )
2018
8
Sweet syndrome following a positive Mantoux test due to pulmonary tuberculosis. ( 30238576 )
2018
9
Pyoderma gangrenosum and Sweet syndrome: the prototypic neutrophilic dermatoses. ( 26202386 )
2018
10
Drug-Induced Sweet Syndrome in a Man With Sarcoidosis: Are There Any Common Mechanisms of Pathogenesis? ( 29538086 )
2018
11
Expanding the differential diagnosis of raccoon eyes: sweet syndrome. ( 29852061 )
2018
12
Sweet syndrome with aseptic splenic abscesses and multiple myeloma. ( 29894540 )
2018
13
Histiocytoid Sweet syndrome successfully treated with etanercept. ( 29904308 )
2018
14
Copresentation of common variable immune deficiency and Sweet syndrome. ( 30063785 )
2018
15
Azathioprine-Induced Sweet Syndrome Treated With Infliximab. ( 30074533 )
2018
16
Idiopathic histiocytoid Sweet syndrome: a case report with clinical and histopathological considerations. ( 30113066 )
2018
17
Bullous sweet syndrome healing with prominent secondary anetoderma. ( 30152553 )
2018
18
Image gallery: Hairy-cell leukaemia presenting with Sweet syndrome. ( 30194758 )
2018
19
Subcutaneous Histiocytoid Sweet Syndrome in a Patient With Relapsed Acute Myeloblastic Leukemia. ( 28291132 )
2018
20
Sweet syndrome presenting as a febrile rash in a returning traveller. ( 28534449 )
2018
21
Necrotizing Sweet Syndrome of the Upper Extremity After Elective Hand Surgery. ( 28935337 )
2018
22
Sweet syndrome caused by sensitization to gabapentin. ( 28958741 )
2018
23
Azacitidine-induced Sweet syndrome: Two unusual clinical presentations. ( 29044459 )
2018
24
Lymphocytes in Sweet syndrome: A potential diagnostic pitfall. ( 29265393 )
2018
25
Potassium iodide in refractory, recurrent pediatric Sweet syndrome: Guidance in dosing and monitoring. ( 29314271 )
2018
26
Sweet syndrome associated with ipilimumab in a patient with metastatic melanoma. ( 29396853 )
2018
27
Sweet syndrome as the leading symptom in the diagnosis of gastric cancer. ( 29486570 )
2018
28
Necrotizing Soft Tissue Infection or Sweet Syndrome: Surgery Versus No Surgery?: A Case Report. ( 28151765 )
2017
29
Sweet Syndrome Associated with Bilateral Nodular Scleritis. ( 29282197 )
2017
30
Sweet Syndrome After Bilateral Deep Inferior Epigastric Perforator Flap Breast Reconstruction: A Case Report. ( 28604546 )
2017
31
Sweet syndrome secondary to myelodysplastic syndrome mimicking necrotizing fasciitis. ( 28589451 )
2017
32
Necrotizing Sweet syndrome in a patient with myelodysplastic syndrome. ( 28422309 )
2017
33
Histiocytoid Sweet Syndrome and Myelodysplastic Syndrome. ( 28614548 )
2017
34
Histiocytoid Sweet Syndrome and Myelodysplastic Syndrome-Reply. ( 28614552 )
2017
35
A rare case report describing the relation between sweet syndrome and spontaneous recurrent peritonitis. ( 28957773 )
2017
36
Ticagrelor-induced Sweet Syndrome: an unusual dermatologic complication after percutaneous coronary intervention. ( 27146134 )
2017
37
Neuro sweet syndrome: a systematic review. A rare complication of Sweet syndrome. ( 27659797 )
2017
38
Acute Myeloid Leukemia Presenting with Sweet Syndrome: A Case Report and Review of the Literature. ( 27720691 )
2017
39
Acral manifestations of Sweet syndrome (neutrophilic dermatosis of the hands). ( 27938816 )
2017
40
Clinicopathologic, immunophenotyping and cytogenetic analysis of Sweet syndrome in Egyptian patients with acute myeloid leukemia. ( 28024959 )
2017
41
A case of Sweet syndrome successfully treated by anti-inflammatory property of doxycycline. ( 28108184 )
2017
42
Clinicopathologic, Immunohistochemical, and Molecular Features of Histiocytoid Sweet Syndrome. ( 28296991 )
2017
43
Sweet Syndrome: Clinical Features, Histopathology, and Associations of 83 Cases. ( 28300447 )
2017
44
Malignancy-associated Sweet syndrome: acute febrile neutrophilic dermatosis associated with recurrence of metastatic cervical cancer. ( 28541876 )
2017
45
Histiocytoid Sweet Syndrome in a Child without Underlying Systemic Disease. ( 28966522 )
2017
46
Sweet syndrome induced by oral acetaminophen-codeine following repair of a facial fracture. ( 29121137 )
2017
47
Neutrophilic Dermatosis of the Hands (Sweet Syndrome of the Hands) Associated With Rheumatoid Arthritis. ( 29258792 )
2017
48
Sweet syndrome-like cutaneous drug reaction. ( 29364449 )
2017
49
Aseptic Splenic Abscess and Sweet Syndrome. ( 27111793 )
2016
50
Aseptic meningitis and anti-I^2-glycoprotein 1 antibodies in Sweet syndrome. ( 27452622 )
2016

Variations for Neutrophilic Dermatosis, Acute Febrile

Expression for Neutrophilic Dermatosis, Acute Febrile

Search GEO for disease gene expression data for Neutrophilic Dermatosis, Acute Febrile.

Pathways for Neutrophilic Dermatosis, Acute Febrile

GO Terms for Neutrophilic Dermatosis, Acute Febrile

Sources for Neutrophilic Dermatosis, Acute Febrile

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