SS
MCID: NTR042
MIFTS: 34

Neutrophilic Dermatosis, Acute Febrile (SS)

Categories: Bone diseases, Rare diseases, Skin diseases

Aliases & Classifications for Neutrophilic Dermatosis, Acute Febrile

MalaCards integrated aliases for Neutrophilic Dermatosis, Acute Febrile:

Name: Neutrophilic Dermatosis, Acute Febrile 58 54
Sweet Syndrome 58 77 54 60 74
Acute Febrile Neutrophilic Dermatosis 77 54 60
Ss 58 54
Acromelic Frontonasal Dysostosis 74
Gomm-Button Disease 58
Gomm Button Disease 54
Sweet Syndrome; Ss 58
Sweets Syndrome 56
Afnd 58

Characteristics:

Orphanet epidemiological data:

60
sweet syndrome
Prevalence: <1/1000000 (Worldwide); Age of onset: Adult;

Classifications:



External Ids:

OMIM 58 608068
MESH via Orphanet 46 D016463
ICD10 via Orphanet 35 L98.2
UMLS via Orphanet 75 C0085077
Orphanet 60 ORPHA3243
MedGen 43 C0085077

Summaries for Neutrophilic Dermatosis, Acute Febrile

NIH Rare Diseases : 54 Acute febrile neutrophilic dermatosis is a skin condition characterized by fever, inflammation of the joints (arthritis), and painful skin lesions that appear mainly on the face, neck, back and arms. Although middle-aged women are most likely to develop this condition, it may also affect men, older adults and even infants. The exact cause of acute febrile neutrophilic dermatosis often isn't known. It is suspected that it can be a reaction of the body to certain exposures (sun), infections (Streptococcus bacteria, Campylobacter), or medications (azathioprine, nonsteroidal anti-inflammatory medications). This condition can also occur with some types of cancer and other serious health problems. Most often, it isn't serious and will clear on its own in a few months. Healing is much more rapid; however, with treatment, such as corticosteroid use.

MalaCards based summary : Neutrophilic Dermatosis, Acute Febrile, also known as sweet syndrome, is related to acromelic frontonasal dysostosis and sickle cell anemia, and has symptoms including seizures An important gene associated with Neutrophilic Dermatosis, Acute Febrile is CSF3 (Colony Stimulating Factor 3). Affiliated tissues include neutrophil, skin and myeloid.

Wikipedia : 77 Sweet''s syndrome (SS), or acute febrile neutrophilic dermatosis is a skin disease characterized by the... more...

Description from OMIM: 608068

Related Diseases for Neutrophilic Dermatosis, Acute Febrile

Diseases related to Neutrophilic Dermatosis, Acute Febrile via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 284)
# Related Disease Score Top Affiliating Genes
1 acromelic frontonasal dysostosis 12.0
2 sickle cell anemia 11.9
3 sjogren syndrome 11.4
4 majeed syndrome 11.2
5 hemoglobin se disease 11.2
6 frontonasal dysplasia 1 11.1
7 schimmelpenning-feuerstein-mims syndrome 11.1
8 fetal hemoglobin quantitative trait locus 5 11.1
9 serotonin syndrome 11.1
10 atrial standstill 1 10.4
11 leukemia 10.4
12 heart block, congenital 10.3
13 adenocarcinoma 10.3
14 myelodysplastic syndrome 10.2
15 annular erythema 10.2
16 distal trisomy 9q 10.2
17 disorganization, mouse, homolog of 10.2
18 lupus erythematosus 10.2
19 connective tissue disease 10.1
20 sickle cell disease 10.1
21 vasculitis 10.1
22 systemic lupus erythematosus 10.1
23 myeloid leukemia 10.1
24 sarcoma 10.1
25 familial thyroid dyshormonogenesis 10.1
26 suppression of tumorigenicity 12 10.0
27 myocardial infarction 10.0
28 dressler's syndrome 10.0
29 anterior scleritis 10.0
30 polyneuropathy 10.0
31 essential thrombocythemia 10.0
32 transitional cell carcinoma 10.0
33 bone marrow cancer 10.0
34 nodular episcleritis 10.0
35 influenza 10.0
36 enteropathy-associated t-cell lymphoma 10.0
37 rheumatoid vasculitis 10.0
38 cellulitis 10.0
39 sarcoma, synovial 10.0
40 premature ejaculation 10.0
41 polymyositis 10.0
42 myeloma, multiple 10.0
43 crohn's disease 10.0
44 melanoma 10.0
45 hairy cell leukemia 10.0
46 alpha-thalassemia 10.0
47 thalassemia 10.0
48 atrioventricular block 10.0
49 hemoglobinopathy 10.0
50 leukemia, acute myeloid 9.9

Graphical network of the top 20 diseases related to Neutrophilic Dermatosis, Acute Febrile:



Diseases related to Neutrophilic Dermatosis, Acute Febrile

Symptoms & Phenotypes for Neutrophilic Dermatosis, Acute Febrile

Clinical features from OMIM:

608068

UMLS symptoms related to Neutrophilic Dermatosis, Acute Febrile:


seizures

Drugs & Therapeutics for Neutrophilic Dermatosis, Acute Febrile

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Observational Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases Recruiting NCT01952275

Search NIH Clinical Center for Neutrophilic Dermatosis, Acute Febrile

Genetic Tests for Neutrophilic Dermatosis, Acute Febrile

Anatomical Context for Neutrophilic Dermatosis, Acute Febrile

MalaCards organs/tissues related to Neutrophilic Dermatosis, Acute Febrile:

42
Neutrophil, Skin, Myeloid, Bone, Lung, Thyroid, Eye

Publications for Neutrophilic Dermatosis, Acute Febrile

Articles related to Neutrophilic Dermatosis, Acute Febrile:

(show top 50) (show all 291)
# Title Authors Year
1
Giant cellulitis-like Sweet syndrome as an initial clinical presentation of acute myeloblastic leukemia with t(6;9)(p23;q34): DEK-CAN and internal duplications of FMS-like tyrosine kinase 3. ( 30659317 )
2019
2
Sweet syndrome in metastatic melanoma during treatment with dabrafenib and trametinib. ( 30724336 )
2019
3
Expanding the differential diagnosis of raccoon eyes: sweet syndrome. ( 29852061 )
2019
4
Histiocytoid Sweet syndrome harboring an isocitrate dehydrogenase 1 mutation: A case report and retrospective analysis of 29 cases of histiocytoid Sweet syndrome. ( 30632174 )
2019
5
Sweet syndrome with pseudocarcinomatous hyperplasia: A case report and review of the literature. ( 30734344 )
2019
6
Sweet syndrome in acute myeloid leukaemia. ( 30788846 )
2019
7
Proliferative Sweet syndrome associated with pregnancy and low-molecular-weight heparin sodium. ( 30907689 )
2019
8
Sweet syndrome in patients with and without malignancy: A retrospective analysis of 83 patients from a tertiary academic referral center. ( 29107342 )
2018
9
Sweet syndrome: a rare feature of ANCA-associated vasculitis or unusual consequence of azathioprine-induced treatment. ( 30455717 )
2018
10
Sweet syndrome after treatment with vedolizumab in a patient with Crohn's disease. ( 29900741 )
2018
11
Sweet syndrome in association with enterobiasis. ( 30187540 )
2018
12
Neutrophilic dermatoses: Pathogenesis, Sweet syndrome, neutrophilic eccrine hidradenitis, and Behçet disease. ( 29653210 )
2018
13
Neonatal lupus erythematosus or Sweet syndrome? ( 30246125 )
2018
14
Sweet Syndrome in a Patient With Systemic Lupus Erythematosus. ( 30247226 )
2018
15
Sweet syndrome following a positive Mantoux test due to pulmonary tuberculosis. ( 30238576 )
2018
16
Pyoderma gangrenosum and Sweet syndrome: the prototypic neutrophilic dermatoses. ( 26202386 )
2018
17
Drug-Induced Sweet Syndrome in a Man With Sarcoidosis: Are There Any Common Mechanisms of Pathogenesis? ( 29538086 )
2018
18
Subcutaneous Histiocytoid Sweet Syndrome in a Patient With Relapsed Acute Myeloblastic Leukemia. ( 28291132 )
2018
19
Sweet syndrome presenting as a febrile rash in a returning traveller. ( 28534449 )
2018
20
Necrotizing Sweet Syndrome of the Upper Extremity After Elective Hand Surgery. ( 28935337 )
2018
21
Sweet syndrome caused by sensitization to gabapentin. ( 28958741 )
2018
22
Azacitidine-induced Sweet syndrome: Two unusual clinical presentations. ( 29044459 )
2018
23
Lymphocytes in Sweet syndrome: A potential diagnostic pitfall. ( 29265393 )
2018
24
Potassium iodide in refractory, recurrent pediatric Sweet syndrome: Guidance in dosing and monitoring. ( 29314271 )
2018
25
Sweet syndrome associated with ipilimumab in a patient with metastatic melanoma. ( 29396853 )
2018
26
Sweet syndrome as the leading symptom in the diagnosis of gastric cancer. ( 29486570 )
2018
27
Sweet syndrome with aseptic splenic abscesses and multiple myeloma. ( 29894540 )
2018
28
Histiocytoid Sweet syndrome successfully treated with etanercept. ( 29904308 )
2018
29
Copresentation of common variable immune deficiency and Sweet syndrome. ( 30063785 )
2018
30
Azathioprine-Induced Sweet Syndrome Treated With Infliximab. ( 30074533 )
2018
31
Idiopathic histiocytoid Sweet syndrome: a case report with clinical and histopathological considerations. ( 30113066 )
2018
32
Bullous sweet syndrome healing with prominent secondary anetoderma. ( 30152553 )
2018
33
Image gallery: Hairy-cell leukaemia presenting with Sweet syndrome. ( 30194758 )
2018
34
Sweet Syndrome in Pediatrics. A case report. ( 30571826 )
2018
35
Superficial and Deep Cutaneous Involvement by RAS-Associated Autoimmunne Leukoproliferative Disease (RALD Cutis): A Histologic Mimicker of Histiocytoid Sweet Syndrome. ( 30601210 )
2018
36
Necrotizing Soft Tissue Infection or Sweet Syndrome: Surgery Versus No Surgery?: A Case Report. ( 28151765 )
2017
37
Sweet Syndrome Associated with Bilateral Nodular Scleritis. ( 29282197 )
2017
38
Sweet Syndrome After Bilateral Deep Inferior Epigastric Perforator Flap Breast Reconstruction: A Case Report. ( 28604546 )
2017
39
Malignancy-associated Sweet syndrome: acute febrile neutrophilic dermatosis associated with recurrence of metastatic cervical cancer. ( 28541876 )
2017
40
Sweet syndrome secondary to myelodysplastic syndrome mimicking necrotizing fasciitis. ( 28589451 )
2017
41
Histiocytoid Sweet Syndrome and Myelodysplastic Syndrome. ( 28614548 )
2017
42
Histiocytoid Sweet Syndrome and Myelodysplastic Syndrome-Reply. ( 28614552 )
2017
43
Necrotizing Sweet syndrome in a patient with myelodysplastic syndrome. ( 28422309 )
2017
44
A rare case report describing the relation between sweet syndrome and spontaneous recurrent peritonitis. ( 28957773 )
2017
45
Neutrophilic Dermatosis of the Hands (Sweet Syndrome of the Hands) Associated With Rheumatoid Arthritis. ( 29258792 )
2017
46
Clinicopathologic, immunophenotyping and cytogenetic analysis of Sweet syndrome in Egyptian patients with acute myeloid leukemia. ( 28024959 )
2017
47
Acute Myeloid Leukemia Presenting with Sweet Syndrome: A Case Report and Review of the Literature. ( 27720691 )
2017
48
Ticagrelor-induced Sweet Syndrome: an unusual dermatologic complication after percutaneous coronary intervention. ( 27146134 )
2017
49
Neuro sweet syndrome: a systematic review. A rare complication of Sweet syndrome. ( 27659797 )
2017
50
Acral manifestations of Sweet syndrome (neutrophilic dermatosis of the hands). ( 27938816 )
2017

Variations for Neutrophilic Dermatosis, Acute Febrile

Expression for Neutrophilic Dermatosis, Acute Febrile

Search GEO for disease gene expression data for Neutrophilic Dermatosis, Acute Febrile.

Pathways for Neutrophilic Dermatosis, Acute Febrile

GO Terms for Neutrophilic Dermatosis, Acute Febrile

Sources for Neutrophilic Dermatosis, Acute Febrile

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