NMZL
MCID: NDL020
MIFTS: 39

Nodal Marginal Zone B-Cell Lymphoma (NMZL)

Categories: Blood diseases, Immune diseases, Rare diseases

Aliases & Classifications for Nodal Marginal Zone B-Cell Lymphoma

MalaCards integrated aliases for Nodal Marginal Zone B-Cell Lymphoma:

Name: Nodal Marginal Zone B-Cell Lymphoma 59
Monocytoid B-Cell Lymphoma 73
Nmzl 59

Classifications:



External Ids:

Orphanet 59 ORPHA86867
ICD10 via Orphanet 34 C83.0
UMLS 73 C0855139

Summaries for Nodal Marginal Zone B-Cell Lymphoma

MalaCards based summary : Nodal Marginal Zone B-Cell Lymphoma, also known as monocytoid b-cell lymphoma, is related to marginal zone b-cell lymphoma and b-cell lymphomas. An important gene associated with Nodal Marginal Zone B-Cell Lymphoma is BCL6 (BCL6, Transcription Repressor), and among its related pathways/superpathways are Notch signaling pathway (KEGG) and NF-kappaB Signaling. Affiliated tissues include b cells, bone and bone marrow.

Related Diseases for Nodal Marginal Zone B-Cell Lymphoma

Diseases related to Nodal Marginal Zone B-Cell Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 36)
# Related Disease Score Top Affiliating Genes
1 marginal zone b-cell lymphoma 30.9 BCL2 BCL6 MALT1
2 b-cell lymphomas 30.9 BCL2 BCL6 MALT1
3 lymphoma 30.9 BCL2 BCL6 MALT1
4 follicular lymphoma 30.1 BCL2 BCL6
5 diffuse large b-cell lymphoma 30.1 BCL6 MALT1
6 hepatitis c virus 10.2
7 hepatitis 10.2
8 keratopathy 10.2
9 hepatitis c 10.2
10 plasmacytoma 10.2
11 composite lymphoma 10.2
12 lymphosarcoma 10.2
13 dacryoadenitis 10.2
14 chronic myelomonocytic leukemia 10.0
15 leukemia 10.0
16 nodal marginal zone lymphoma 10.0
17 pdgfrb-associated chronic eosinophilic leukemia 10.0
18 chromosomal triplication 10.0 BCL6 MALT1
19 central nervous system lymphoma 10.0 BCL6 MALT1
20 primary effusion lymphoma 9.9 BCL6 MALT1
21 lung lymphoma 9.9 BCL6 MALT1
22 splenic marginal zone lymphoma 9.9 BCL6 MALT1
23 leukocyte disease 9.9 BCL6 MALT1
24 high grade b-cell lymphoma with myc and/ or bcl2 and/or bcl6 rearrangement 9.9 BCL2 BCL6
25 follicular lymphoma 1 9.9 BCL2 BCL6
26 intravascular large b-cell lymphoma 9.9 BCL2 BCL6
27 primary mediastinal large b-cell lymphoma 9.9 BCL2 BCL6
28 primary central nervous system lymphoma 9.9 BCL2 BCL6
29 human herpesvirus 8 9.8 BCL2 BCL6
30 autoimmune lymphoproliferative syndrome, type v 9.8 BCL2 BCL6
31 gastric lymphoma 9.8 BCL2 BCL6
32 burkitt lymphoma 9.7 BCL2 BCL6
33 lymphoma, mucosa-associated lymphoid type 9.7 BCL2 BCL6 MALT1
34 mantle cell lymphoma 9.7 BCL2 BCL6 MALT1
35 lymphoma, non-hodgkin, familial 9.7 BCL2 BCL6 MALT1
36 leukemia, chronic lymphocytic 9.6 BCL2 BCL6

Graphical network of the top 20 diseases related to Nodal Marginal Zone B-Cell Lymphoma:



Diseases related to Nodal Marginal Zone B-Cell Lymphoma

Symptoms & Phenotypes for Nodal Marginal Zone B-Cell Lymphoma

Drugs & Therapeutics for Nodal Marginal Zone B-Cell Lymphoma

Search Clinical Trials , NIH Clinical Center for Nodal Marginal Zone B-Cell Lymphoma

Genetic Tests for Nodal Marginal Zone B-Cell Lymphoma

Anatomical Context for Nodal Marginal Zone B-Cell Lymphoma

MalaCards organs/tissues related to Nodal Marginal Zone B-Cell Lymphoma:

41
B Cells, Bone, Bone Marrow, T Cells, Liver, Breast, Myeloid

Publications for Nodal Marginal Zone B-Cell Lymphoma

Articles related to Nodal Marginal Zone B-Cell Lymphoma:

(show top 50) (show all 69)
# Title Authors Year
1
The bendamustine plus rituximab regimen is active against primary nodal marginal zone B-cell lymphoma. ( 27443419 )
2016
2
IgG4-related dacryoadenitis evolving into an extra-nodal, marginal zone B-cell lymphoma (EMZL): a tale of two lacrimal glands. ( 24977741 )
2014
3
Nodal marginal zone B-cell lymphoma showing prominent plasma cell differentiation in the pleural effusion: A case report. ( 22833332 )
2014
4
Localized conjunctival extra-nodal marginal zone B cell lymphoma with presumed Paraproteinic Crystalline Keratopathy. ( 23361873 )
2013
5
Treatment outcome of gastric extra-nodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type in the Hong Kong Chinese population: a single centre experience. ( 23730516 )
2013
6
First report of nodal marginal zone B-cell lymphoma associated with breast implants. ( 22374026 )
2012
7
Nodal marginal zone B cell lymphoma with prominent follicular colonization with deletion of chromosome 13. ( 22963839 )
2012
8
Nodal marginal zone B-cell lymphoma: a diagnostic and therapeutic dilemma. ( 22393802 )
2012
9
Cavitary pulmonary involvement of diffuse large B-cell lymphoma transformed from extra nodal marginal zone B-cell lymphoma MALT type. ( 26189744 )
2011
10
Secondary nodal marginal zone B cell lymphoma arising in primary mixed cellularity subtype of Hodgkin's lymphoma. ( 19125250 )
2009
11
Immunoarchitectural patterns in nodal marginal zone B-cell lymphoma: a study of 51 cases. ( 19864232 )
2009
12
Nodal marginal zone B-cell lymphoma with prominent follicular colonization - difficulties in diagnosis: a study of 15 cases. ( 18269584 )
2008
13
Clinical implications of nodal marginal zone B-cell lymphoma among Japanese: study of 65 cases. ( 17052258 )
2007
14
Primary nodal marginal zone B-cell lymphoma: clinical features and prognostic assessment of a rare disease. ( 17233821 )
2007
15
Genome-wide array-based comparative genomic hybridization of ocular marginal zone B cell lymphoma: comparison with pulmonary and nodal marginal zone B cell lymphoma. ( 17492759 )
2007
16
Nodal marginal zone B-cell lymphoma associated with SjAPgren's syndrome: a report of three cases. ( 17577789 )
2007
17
CD20+ nodal marginal zone B-cell lymphoma with CD20-recurrence as an intracranial dural-based mass. ( 17071504 )
2006
18
Nodal marginal zone B-cell lymphoma: Analysis of 36 cases. Clinical presentation and treatment outcomes of nodal marginal zone B-cell lymphoma. ( 16847665 )
2006
19
A clinicopathological study of nodal marginal zone B-cell lymphoma. A report on 21 cases. ( 16405665 )
2006
20
Florid monocytoid B-cell hyperplasia resembling nodal marginal zone B-cell lymphoma of mucosa associated lymphoid tissue type. A histological and immunohistochemical study of four cases. ( 16989959 )
2006
21
Follicular colonization of nodal marginal-zone B-cell lymphoma resembling follicular lymphoma: report of 6 cases. ( 15735858 )
2005
22
A common clonal origin of nodal marginal zone B-cell lymphoma and plasma cell myeloma demonstrating different immunophenotypes: a case report of composite lymphoma. ( 15167008 )
2004
23
Nodal marginal zone B-cell lymphoma with a novel t(X;5)(q28;q22): conventional and molecular cytogenetic analysis. ( 12781450 )
2003
24
Nodal marginal zone B-cell lymphoma resembling plasmacytoma arising from a plasma cell variant of localized Castleman's disease: a case report. ( 12390409 )
2002
25
Immunoglobulin gene mutations and frequent use of VH1-69 and VH4-34 segments in hepatitis C virus-positive and hepatitis C virus-negative nodal marginal zone B-cell lymphoma. ( 11438472 )
2001
26
Detection of AP12-MALT1 chimaeric gene in extranodal and nodal marginal zone B-cell lymphoma by reverse transcription polymerase chain reaction (PCR) and genomic long and accurate PCR analyses. ( 11736940 )
2001
27
Primary nodal marginal zone B-cell lymphoma arising from more than one clonal neoplastic population. ( 11100064 )
2000
28
Retreatment with chimeric CD 20 monoclonal antibody in a patient with nodal marginal zone B-cell lymphoma. ( 10962535 )
2000
29
Transformation of monocytoid B-cell lymphoma to large cell lymphoma associated with crystal-storing histiocytes. ( 10705408 )
2000
30
Nodal monocytoid B-cell lymphoma (nodal marginal-zone B-cell lymphoma). ( 10319381 )
1999
31
Pleural involvement in a case of monocytoid B-cell lymphoma. ( 10509045 )
1999
32
Nodal marginal zone B-cell lymphoma with peculiar follicular colonization involved by malignant lymphoma of thyroid gland. ( 9870160 )
1998
33
Marginal zone B-cell lymphomas including mucosa-associated lymphoid tissue type lymphoma (MALT), monocytoid B-cell lymphoma and splenic marginal zone cell lymphoma and their relation to the reactive marginal zone. ( 9389354 )
1997
34
Molecular Ig gene analysis reveals that monocytoid B cell lymphoma is a malignancy of mature B cells carrying somatically mutated V region genes and suggests that rearrangement of the kappa-deleting element (resulting in deletion of the Ig kappa enhancers) abolishes somatic hypermutation in the human. ( 8765023 )
1996
35
Chronic lymphocytic leukemia with an interfollicular architecture: avoiding diagnostic confusion with monocytoid B-cell lymphoma. ( 8580823 )
1995
36
Correspondence Re: Abraham NZ, Maher TJ, Hutchison RE: Extra-nodal monocytoid B-cell lymphoma of the urinary bladder. Mod Pathol 6:145, 1993. ( 7695764 )
1994
37
UCL3D3 and UCL4D12 reactivity in small B-cell neoplasms with special emphasis on monocytoid B-cell lymphoma. ( 7927314 )
1994
38
Response to radiation in chemotherapy-refractory monocytoid B-cell lymphoma: a case report. ( 7977306 )
1994
39
Immunohistochemical characteristics of monocytoid B cell lymphoma, mantle zone lymphoma, small lymphocytic lymphoma (or B chronic lymphocytic leukemia), and hairy cell leukemia. ( 8285023 )
1993
40
Lack of evidence of Epstein-Barr virus in hairy cell leukemia and monocytoid B-cell lymphoma. ( 8380277 )
1993
41
Extra-nodal monocytoid B-cell lymphoma of the urinary bladder. ( 7695654 )
1993
42
CD5+ leukemic monocytoid B-cell lymphoma and lymphocytic lymphomas. ( 7689294 )
1993
43
Cytogenetic studies of composite lymphomas: monocytoid B-cell lymphoma and other B-cell non-Hodgkin's lymphomas. ( 7691710 )
1993
44
Low-grade B-cell lymphoma of mucosa-associated lymphoid tissue and monocytoid B-cell lymphoma. Related entities that are distinct from other low-grade B-cell lymphomas. ( 8343039 )
1993
45
Monocytoid B-cell lymphoma: its relationship to and possible cellular origin from marginal zone cells. ( 8454278 )
1993
46
Monocytoid B-cell lymphoma. ( 8475908 )
1993
47
Antigenic phenotypes of hairy cell leukemia and monocytoid B-cell lymphoma: an immunohistochemical evaluation of 66 cases. ( 1740301 )
1992
48
Monocytoid B-cell lymphoma of the prostate. ( 1465326 )
1992
49
The morphological spectrum of monocytoid B-cell lymphoma and its relationship to lymphomas of mucosa-associated lymphoid tissue. ( 1468755 )
1992
50
Plasmacytic differentiation in parafollicular (monocytoid) B-cell lymphoma. A study of 12 cases. ( 1471727 )
1992

Variations for Nodal Marginal Zone B-Cell Lymphoma

Expression for Nodal Marginal Zone B-Cell Lymphoma

Search GEO for disease gene expression data for Nodal Marginal Zone B-Cell Lymphoma.

Pathways for Nodal Marginal Zone B-Cell Lymphoma

GO Terms for Nodal Marginal Zone B-Cell Lymphoma

Biological processes related to Nodal Marginal Zone B-Cell Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.4 BCL2 BCL6
2 negative regulation of cell growth GO:0030308 9.37 BCL2 BCL6
3 negative regulation of apoptotic process GO:0043066 9.33 BCL2 BCL6 MALT1
4 B cell differentiation GO:0030183 9.32 BCL2 BCL6
5 cell morphogenesis GO:0000902 9.26 BCL2 BCL6
6 positive regulation of B cell proliferation GO:0030890 8.96 BCL2 BCL6
7 regulation of apoptotic process GO:0042981 8.8 BCL2 BCL6 MALT1

Molecular functions related to Nodal Marginal Zone B-Cell Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.13 BCL2 BCL6 MALT1
2 protease binding GO:0002020 8.62 BCL2 MALT1

Sources for Nodal Marginal Zone B-Cell Lymphoma

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11 DGIdb
17 ExPASy
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33 ICD10
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58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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