NMZL
MCID: NDL020
MIFTS: 30

Nodal Marginal Zone B-Cell Lymphoma (NMZL)

Categories: Blood diseases, Immune diseases, Rare diseases

Aliases & Classifications for Nodal Marginal Zone B-Cell Lymphoma

MalaCards integrated aliases for Nodal Marginal Zone B-Cell Lymphoma:

Name: Nodal Marginal Zone B-Cell Lymphoma 60
Monocytoid B-Cell Lymphoma 74
Nmzl 60

Classifications:



External Ids:

ICD10 via Orphanet 35 C83.0
Orphanet 60 ORPHA86867
UMLS 74 C0855139

Summaries for Nodal Marginal Zone B-Cell Lymphoma

MalaCards based summary : Nodal Marginal Zone B-Cell Lymphoma, also known as monocytoid b-cell lymphoma, is related to marginal zone b-cell lymphoma and lymphoma. An important gene associated with Nodal Marginal Zone B-Cell Lymphoma is BCL6 (BCL6 Transcription Repressor), and among its related pathways/superpathways are Notch signaling pathway (KEGG) and NF-kappaB Signaling. Affiliated tissues include b cells, colon and bone.

Related Diseases for Nodal Marginal Zone B-Cell Lymphoma

Diseases related to Nodal Marginal Zone B-Cell Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 34)
# Related Disease Score Top Affiliating Genes
1 marginal zone b-cell lymphoma 30.7 BCL2 BCL6 MALT1
2 lymphoma 30.7 BCL2 BCL6 MALT1
3 b-cell lymphomas 30.7 BCL2 BCL6 MALT1
4 follicular lymphoma 30.0 BCL2 BCL6
5 diffuse large b-cell lymphoma 30.0 BCL6 MALT1
6 hepatitis c virus 10.2
7 hepatitis 10.2
8 keratopathy 10.2
9 hepatitis c 10.2
10 plasmacytoma 10.2
11 composite lymphoma 10.2
12 lymphosarcoma 10.2
13 dacryoadenitis 10.2
14 chronic myelomonocytic leukemia 10.0
15 leukemia 10.0
16 nodal marginal zone lymphoma 10.0
17 pdgfrb-associated chronic eosinophilic leukemia 10.0
18 chromosomal triplication 9.9 BCL6 MALT1
19 central nervous system lymphoma 9.9 BCL6 MALT1
20 lung lymphoma 9.9 BCL6 MALT1
21 splenic marginal zone lymphoma 9.9 BCL6 MALT1
22 leukocyte disease 9.8 BCL6 MALT1
23 high grade b-cell lymphoma with myc and/ or bcl2 and/or bcl6 rearrangement 9.8 BCL2 BCL6
24 follicular lymphoma 1 9.8 BCL2 BCL6
25 intravascular large b-cell lymphoma 9.8 BCL2 BCL6
26 primary central nervous system lymphoma 9.8 BCL2 BCL6
27 human herpesvirus 8 9.7 BCL2 BCL6
28 autoimmune lymphoproliferative syndrome, type v 9.7 BCL2 BCL6
29 gastric lymphoma 9.7 BCL2 BCL6
30 burkitt lymphoma 9.6 BCL2 BCL6
31 lymphoma, mucosa-associated lymphoid type 9.5 BCL2 BCL6 MALT1
32 mantle cell lymphoma 9.5 BCL2 BCL6 MALT1
33 lymphoma, non-hodgkin, familial 9.5 BCL2 BCL6 MALT1
34 leukemia, chronic lymphocytic 9.4 BCL2 BCL6

Graphical network of the top 20 diseases related to Nodal Marginal Zone B-Cell Lymphoma:



Diseases related to Nodal Marginal Zone B-Cell Lymphoma

Symptoms & Phenotypes for Nodal Marginal Zone B-Cell Lymphoma

Drugs & Therapeutics for Nodal Marginal Zone B-Cell Lymphoma

Search Clinical Trials , NIH Clinical Center for Nodal Marginal Zone B-Cell Lymphoma

Genetic Tests for Nodal Marginal Zone B-Cell Lymphoma

Anatomical Context for Nodal Marginal Zone B-Cell Lymphoma

MalaCards organs/tissues related to Nodal Marginal Zone B-Cell Lymphoma:

42
B Cells, Colon, Bone, Bone Marrow, Lymph Node, Breast, Thyroid

Publications for Nodal Marginal Zone B-Cell Lymphoma

Articles related to Nodal Marginal Zone B-Cell Lymphoma:

(show top 50) (show all 70)
# Title Authors Year
1
A patient with a diagnosis of nodal marginal zone B-cell lymphoma and a t(2;14)(p24;q32) involving MYCN and IGH. ( 30733831 )
2019
2
The bendamustine plus rituximab regimen is active against primary nodal marginal zone B-cell lymphoma. ( 27443419 )
2016
3
IgG4-related dacryoadenitis evolving into an extra-nodal, marginal zone B-cell lymphoma (EMZL): a tale of two lacrimal glands. ( 24977741 )
2014
4
Nodal marginal zone B-cell lymphoma showing prominent plasma cell differentiation in the pleural effusion: A case report. ( 22833332 )
2014
5
Localized conjunctival extra-nodal marginal zone B cell lymphoma with presumed Paraproteinic Crystalline Keratopathy. ( 23361873 )
2013
6
Treatment outcome of gastric extra-nodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type in the Hong Kong Chinese population: a single centre experience. ( 23730516 )
2013
7
First report of nodal marginal zone B-cell lymphoma associated with breast implants. ( 22374026 )
2012
8
Nodal marginal zone B cell lymphoma with prominent follicular colonization with deletion of chromosome 13. ( 22963839 )
2012
9
Nodal marginal zone B-cell lymphoma: a diagnostic and therapeutic dilemma. ( 22393802 )
2012
10
Cavitary pulmonary involvement of diffuse large B-cell lymphoma transformed from extra nodal marginal zone B-cell lymphoma MALT type. ( 26189744 )
2011
11
Secondary nodal marginal zone B cell lymphoma arising in primary mixed cellularity subtype of Hodgkin's lymphoma. ( 19125250 )
2009
12
Immunoarchitectural patterns in nodal marginal zone B-cell lymphoma: a study of 51 cases. ( 19864232 )
2009
13
Nodal marginal zone B-cell lymphoma with prominent follicular colonization - difficulties in diagnosis: a study of 15 cases. ( 18269584 )
2008
14
Clinical implications of nodal marginal zone B-cell lymphoma among Japanese: study of 65 cases. ( 17052258 )
2007
15
Primary nodal marginal zone B-cell lymphoma: clinical features and prognostic assessment of a rare disease. ( 17233821 )
2007
16
Genome-wide array-based comparative genomic hybridization of ocular marginal zone B cell lymphoma: comparison with pulmonary and nodal marginal zone B cell lymphoma. ( 17492759 )
2007
17
Nodal marginal zone B-cell lymphoma associated with SjAPgren's syndrome: a report of three cases. ( 17577789 )
2007
18
CD20+ nodal marginal zone B-cell lymphoma with CD20-recurrence as an intracranial dural-based mass. ( 17071504 )
2006
19
Nodal marginal zone B-cell lymphoma: Analysis of 36 cases. Clinical presentation and treatment outcomes of nodal marginal zone B-cell lymphoma. ( 16847665 )
2006
20
A clinicopathological study of nodal marginal zone B-cell lymphoma. A report on 21 cases. ( 16405665 )
2006
21
Florid monocytoid B-cell hyperplasia resembling nodal marginal zone B-cell lymphoma of mucosa associated lymphoid tissue type. A histological and immunohistochemical study of four cases. ( 16989959 )
2006
22
Follicular colonization of nodal marginal-zone B-cell lymphoma resembling follicular lymphoma: report of 6 cases. ( 15735858 )
2005
23
A common clonal origin of nodal marginal zone B-cell lymphoma and plasma cell myeloma demonstrating different immunophenotypes: a case report of composite lymphoma. ( 15167008 )
2004
24
Nodal marginal zone B-cell lymphoma with a novel t(X;5)(q28;q22): conventional and molecular cytogenetic analysis. ( 12781450 )
2003
25
Nodal marginal zone B-cell lymphoma resembling plasmacytoma arising from a plasma cell variant of localized Castleman's disease: a case report. ( 12390409 )
2002
26
Immunoglobulin gene mutations and frequent use of VH1-69 and VH4-34 segments in hepatitis C virus-positive and hepatitis C virus-negative nodal marginal zone B-cell lymphoma. ( 11438472 )
2001
27
Detection of AP12-MALT1 chimaeric gene in extranodal and nodal marginal zone B-cell lymphoma by reverse transcription polymerase chain reaction (PCR) and genomic long and accurate PCR analyses. ( 11736940 )
2001
28
Primary nodal marginal zone B-cell lymphoma arising from more than one clonal neoplastic population. ( 11100064 )
2000
29
Retreatment with chimeric CD 20 monoclonal antibody in a patient with nodal marginal zone B-cell lymphoma. ( 10962535 )
2000
30
Transformation of monocytoid B-cell lymphoma to large cell lymphoma associated with crystal-storing histiocytes. ( 10705408 )
2000
31
Nodal monocytoid B-cell lymphoma (nodal marginal-zone B-cell lymphoma). ( 10319381 )
1999
32
Pleural involvement in a case of monocytoid B-cell lymphoma. ( 10509045 )
1999
33
Nodal marginal zone B-cell lymphoma with peculiar follicular colonization involved by malignant lymphoma of thyroid gland. ( 9870160 )
1998
34
Marginal zone B-cell lymphomas including mucosa-associated lymphoid tissue type lymphoma (MALT), monocytoid B-cell lymphoma and splenic marginal zone cell lymphoma and their relation to the reactive marginal zone. ( 9389354 )
1997
35
Molecular Ig gene analysis reveals that monocytoid B cell lymphoma is a malignancy of mature B cells carrying somatically mutated V region genes and suggests that rearrangement of the kappa-deleting element (resulting in deletion of the Ig kappa enhancers) abolishes somatic hypermutation in the human. ( 8765023 )
1996
36
Chronic lymphocytic leukemia with an interfollicular architecture: avoiding diagnostic confusion with monocytoid B-cell lymphoma. ( 8580823 )
1995
37
Correspondence Re: Abraham NZ, Maher TJ, Hutchison RE: Extra-nodal monocytoid B-cell lymphoma of the urinary bladder. Mod Pathol 6:145, 1993. ( 7695764 )
1994
38
UCL3D3 and UCL4D12 reactivity in small B-cell neoplasms with special emphasis on monocytoid B-cell lymphoma. ( 7927314 )
1994
39
Response to radiation in chemotherapy-refractory monocytoid B-cell lymphoma: a case report. ( 7977306 )
1994
40
Low-grade B-cell lymphoma of mucosa-associated lymphoid tissue and monocytoid B-cell lymphoma. Related entities that are distinct from other low-grade B-cell lymphomas. ( 8343039 )
1993
41
Immunohistochemical characteristics of monocytoid B cell lymphoma, mantle zone lymphoma, small lymphocytic lymphoma (or B chronic lymphocytic leukemia), and hairy cell leukemia. ( 8285023 )
1993
42
Lack of evidence of Epstein-Barr virus in hairy cell leukemia and monocytoid B-cell lymphoma. ( 8380277 )
1993
43
Extra-nodal monocytoid B-cell lymphoma of the urinary bladder. ( 7695654 )
1993
44
CD5+ leukemic monocytoid B-cell lymphoma and lymphocytic lymphomas. ( 7689294 )
1993
45
Cytogenetic studies of composite lymphomas: monocytoid B-cell lymphoma and other B-cell non-Hodgkin's lymphomas. ( 7691710 )
1993
46
Monocytoid B-cell lymphoma: its relationship to and possible cellular origin from marginal zone cells. ( 8454278 )
1993
47
Monocytoid B-cell lymphoma. ( 8475908 )
1993
48
Antigenic phenotypes of hairy cell leukemia and monocytoid B-cell lymphoma: an immunohistochemical evaluation of 66 cases. ( 1740301 )
1992
49
Monocytoid B-cell lymphoma of the prostate. ( 1465326 )
1992
50
The morphological spectrum of monocytoid B-cell lymphoma and its relationship to lymphomas of mucosa-associated lymphoid tissue. ( 1468755 )
1992

Variations for Nodal Marginal Zone B-Cell Lymphoma

Expression for Nodal Marginal Zone B-Cell Lymphoma

Search GEO for disease gene expression data for Nodal Marginal Zone B-Cell Lymphoma.

Pathways for Nodal Marginal Zone B-Cell Lymphoma

GO Terms for Nodal Marginal Zone B-Cell Lymphoma

Biological processes related to Nodal Marginal Zone B-Cell Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.4 BCL2 BCL6
2 negative regulation of cell growth GO:0030308 9.37 BCL2 BCL6
3 negative regulation of apoptotic process GO:0043066 9.33 BCL2 BCL6 MALT1
4 B cell differentiation GO:0030183 9.32 BCL2 BCL6
5 cell morphogenesis GO:0000902 9.26 BCL2 BCL6
6 positive regulation of B cell proliferation GO:0030890 8.96 BCL2 BCL6
7 regulation of apoptotic process GO:0042981 8.8 BCL2 BCL6 MALT1

Molecular functions related to Nodal Marginal Zone B-Cell Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.13 BCL2 BCL6 MALT1
2 protease binding GO:0002020 8.62 BCL2 MALT1

Sources for Nodal Marginal Zone B-Cell Lymphoma

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17 EFO
18 ExPASy
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59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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