MCID: NDL006
MIFTS: 24

Nodular Prostate

Categories: Reproductive diseases

Aliases & Classifications for Nodular Prostate

MalaCards integrated aliases for Nodular Prostate:

Name: Nodular Prostate 12 54 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:13206
ICD9CM 34 600.1
ICD10 32 N40
UMLS 70 C0748012

Summaries for Nodular Prostate

MalaCards based summary : Nodular Prostate is related to prostate stromal sarcoma and prostate adenoid cystic carcinoma. An important gene associated with Nodular Prostate is KLK3 (Kallikrein Related Peptidase 3), and among its related pathways/superpathways are Androgen receptor signaling pathway and Regulation of Wnt-mediated beta catenin signaling and target gene transcription. Affiliated tissues include prostate, pineal and lung, and related phenotype is normal.

Related Diseases for Nodular Prostate

Diseases related to Nodular Prostate via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 157)
# Related Disease Score Top Affiliating Genes
1 prostate stromal sarcoma 10.2 SYP KLK3
2 prostate adenoid cystic carcinoma 10.2 KLK3 AR
3 prostate leiomyoma 10.2 KLK3 AR
4 prostate calculus 10.2 KLK3 AR
5 bronchiectasis 3 10.1 KLK3 AR
6 prostatic acinar adenocarcinoma 10.1 KLK3 AR
7 prostatic hyperplasia, benign 10.1 KLK3 AR
8 prostate transitional cell carcinoma 10.1 KLK3 AR
9 male reproductive organ benign neoplasm 10.1 KLK3 AR
10 ovarian endometrioid stromal sarcoma 10.1 SYP AR
11 prostatic adenoma 10.1 KLK3 AR
12 withdrawal disorder 10.1 KLK3 AR
13 sclerosing hemangioma 10.1 SYP ENO2
14 prostatic hypertrophy 10.1 KLK3 AR
15 malignant melanocytic neoplasm of the peripheral nerve sheath 10.1 SYP ENO2
16 anal neuroendocrine tumor 10.1 SYP ENO2
17 optic nerve astrocytoma 10.1 SYP ENO2
18 cerebral neuroblastoma 10.1 SYP ENO2
19 neuronal intestinal dysplasia, type b 10.1 SYP ENO2
20 lung meningioma 10.1 SYP ENO2
21 sinonasal undifferentiated carcinoma 10.1 SYP ENO2
22 auditory system benign neoplasm 10.1 SYP ENO2
23 papillary tumor of the pineal region 10.1 SYP ENO2
24 auditory system cancer 10.1 SYP ENO2
25 cloacogenic carcinoma 10.1 SYP ENO2
26 pineal region teratoma 10.1 SYP ENO2
27 extraosseous ewings sarcoma-primitive neuroepithelial tumor 10.1 SYP ENO2
28 cauda equina neoplasm 10.1 SYP ENO2
29 intracranial primitive neuroectodermal tumor 10.1 SYP ENO2
30 cystadenoma 10.1 SYP KLK3
31 bile duct mucinous adenocarcinoma 10.1 SYP ENO2
32 ampulla of vater benign neoplasm 10.1 SYP ENO2
33 appendix carcinoid tumor 10.1 SYP ENO2
34 carotid body cancer 10.1 SYP ENO2
35 gallbladder small cell carcinoma 10.1 SYP ENO2
36 ureter small cell carcinoma 10.1 SYP ENO2
37 cerebellar liponeurocytoma 10.1 SYP ENO2
38 middle ear adenoma 10.1 SYP ENO2
39 cerebellopontine angle primitive neuroectodermal tumor 10.1 SYP ENO2
40 lymph node carcinoma 10.1 KLK3 AR
41 urinary bladder small cell neuroendocrine carcinoma 10.1 SYP ENO2
42 neuroendocrine carcinoma 10.1 SYP ENO2
43 gastric small cell carcinoma 10.1 SYP ENO2
44 extracranial neuroblastoma 10.1 SYP ENO2
45 jejunal neoplasm 10.1 SYP ENO2
46 frontal lobe neoplasm 10.1 SYP ENO2
47 sensory organ benign neoplasm 10.1 SYP ENO2
48 sweat gland cancer 10.1 SYP AR
49 cervical neuroblastoma 10.1 SYP ENO2
50 ovarian large-cell neuroendocrine carcinoma 10.1 SYP ENO2

Graphical network of the top 20 diseases related to Nodular Prostate:



Diseases related to Nodular Prostate

Symptoms & Phenotypes for Nodular Prostate

MGI Mouse Phenotypes related to Nodular Prostate:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 normal MP:0002873 9.02 AR KLK3 MMP10 SYP VCAN

Drugs & Therapeutics for Nodular Prostate

Search Clinical Trials , NIH Clinical Center for Nodular Prostate

Genetic Tests for Nodular Prostate

Anatomical Context for Nodular Prostate

MalaCards organs/tissues related to Nodular Prostate:

40
Prostate, Pineal, Lung, Breast, Kidney, Bone, Lymph Node

Publications for Nodular Prostate

Articles related to Nodular Prostate:

(show all 23)
# Title Authors PMID Year
1
Prostate cancer masquerading as a zygomatic posttraumatic mass. 54 61
9070201 1997
2
Primary diffuse large B cell lymphoma (DLBCL) of the prostate presenting with lower urinary tract symptoms (LUTS). 61
33370963 2020
3
Histopathology, pharmacotherapy, and predictors of prostatic malignancy in elderly male patients with raised prostate-specific antigen levels - A prospective study. 61
32565650 2020
4
Stimulation of Prostate Cells by the Senescence Phenotype of Epithelial and Stromal Cells: Implication for Benign Prostate Hyperplasia. 61
31844843 2019
5
Synchronous Detection of Male Breast Cancer and Prostatic Cancer in a Patient With Suspected Prostatic Carcinoma on 68Ga-PSMA PET/CT Imaging. 61
29538032 2018
6
Genetic polymorphisms in key hypoxia-regulated downstream molecules and phenotypic correlation in prostate cancer. 61
28143503 2017
7
[Leiomyosarcoma of the prostate treated with neoadjuvant intra-arterial chemotherapy and pelvic excenteration ; a case report]. 61
25511947 2014
8
Advanced carcinoma of the prostate presenting as a supraclavicular mass: case report. 61
25331247 2014
9
Clinico-pathological Correlation of Digital Rectal Examination Findings Amongst Nigerian Men with Prostatic Diseases: A Prospective Study of 236 Cases. 61
24027415 2013
10
Synchronous penile metastasis from a high-grade adenocarcinoma of the prostate. 61
23119219 2012
11
Adenoid cystic carcinoma of the prostate: case report on a rare entity and review of the literature. 61
21440997 2011
12
Hypocalcemia with bony metastases in prostate cancer. 61
19024209 2008
13
[Changes in the urinary bladder caused by short-term permanent catheter insertion]. 61
18724530 2008
14
Testicular metastasis from carcinoma of prostate: report of two cases. 61
17224911 2007
15
[Small cell carcinoma of the prostate: an autopsy case report]. 61
16050480 2005
16
[Primary malignant lymphoma of the prostate: report of a case achieving complete response to combination chemotherapy and review of 22 Japanese cases]. 61
14531272 2003
17
Prevalence of elevated serum prostate-specific antigen in rural Nigeria. 61
12757603 2003
18
Multiple bilateral cannon-ball lung metastases from carcinoma of the prostate: orchiedectomy induced remission. 61
14569728 2002
19
Critical evaluation of the current indications for transition zone biopsies. 61
11377321 2001
20
Primary squamous cell carcinoma of the prostate: a rare clinicopathological entity. Report of 2 cases and review of literature. 61
11385309 2001
21
The significance of the prostatic hypoechoic area: results in 226 ultrasonically guided prostatic biopsies. 61
1688955 1990
22
[Early diagnosis of cancer of the prostate. Hypothetic role of transrectal echography]. 61
2528133 1989
23
Prostatic ultrasound. 61
3325122 1987

Variations for Nodular Prostate

Expression for Nodular Prostate

Search GEO for disease gene expression data for Nodular Prostate.

Pathways for Nodular Prostate

GO Terms for Nodular Prostate

Biological processes related to Nodular Prostate according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of systemic arterial blood pressure GO:0003073 8.62 KLK3 AR

Sources for Nodular Prostate

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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