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MCID: NDL013
MIFTS: 52

Nodular Regenerative Hyperplasia

Categories: Rare diseases, Liver diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Nodular Regenerative Hyperplasia

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MalaCards integrated aliases for Nodular Regenerative Hyperplasia:

Name: Nodular Regenerative Hyperplasia 53 73
Nodular Regenerative Hyperplasia of the Liver 53 59
Non-Cirrhotic Nodulation 53 59
Non-Cirrhotic Nodular Transformation 53
Miliary Hepatocellular Adenomatosis 53
Non-Cirrhotic Portal Hypertension 53
Nodular Hyperplasia 73

Characteristics:

Orphanet epidemiological data:

59
nodular regenerative hyperplasia of the liver
Inheritance: Not applicable; Age of onset: Adult;

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Liver diseases
See all MalaCards categories (disease lists)
ICD10: 34
Orphanet: 59  
Rare hepatic diseases


External Ids:

Orphanet 59 ORPHA48372
ICD10 via Orphanet 34 K76.8
SNOMED-CT via HPO 69 34742003
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Summaries for Nodular Regenerative Hyperplasia

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NIH Rare Diseases : 53 The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs.Orpha Number: 48372Disease definitionNodular regenerative hyperplasia of the liver is a rare parenchymatous liver disease characterized by diffuse benign transformation of the hepatic parenchyma into multiple small nodules (composed of regenerating hepatocytes) and that is usually asymptomatic but can lead to the development of non-cirrhotic portal hypertension and its complications, including esophageal variceal bleeding, hypersplenism and ascites. It is often associated with rheumatologic, autoimmune, hematologic, and myeloproliferative disorders as well as various immune deficiency states and exposure certain drugs and toxins.Visit the Orphanet disease page for more resources.

MalaCards based summary : Nodular Regenerative Hyperplasia, also known as nodular regenerative hyperplasia of the liver, is related to portal hypertension and hepatitis. An important gene associated with Nodular Regenerative Hyperplasia is NOTCH1 (Notch 1), and among its related pathways/superpathways are Notch signaling pathway (KEGG) and Th17 cell differentiation. The drugs Caffeine and Mesalamine have been mentioned in the context of this disorder. Affiliated tissues include liver, bone marrow and bone, and related phenotypes are portal hypertension and abnormality of the hepatic vasculature

Wikipedia : 76 Nodular regenerative hyperplasia is a form of liver hyperplasia associated with portal hypertension.... more...

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Related Diseases for Nodular Regenerative Hyperplasia

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Diseases related to Nodular Regenerative Hyperplasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 111)
# Related Disease Score Top Affiliating Genes
1 portal hypertension 10.6
2 hepatitis 10.5
3 inflammatory bowel disease 10.3
4 hepatocellular carcinoma 10.3
5 primary biliary cirrhosis 10.3
6 lupus erythematosus 10.3
7 primary biliary cholangitis 10.3
8 biliary cirrhosis, primary, 1 10.3
9 systemic lupus erythematosus 10.2
10 liver disease 10.2
11 pulmonary hypertension 10.2
12 peliosis hepatis 10.2
13 hepatoportal sclerosis 10.2
14 celiac disease 1 10.2
15 lymphoma 10.2
16 crest syndrome 10.2
17 common variable immunodeficiency 10.2
18 scleroderma, familial progressive 10.1
19 polyarteritis nodosa, childhood-onset 10.1
20 budd-chiari syndrome 10.1
21 polyarteritis nodosa 10.1
22 glomerulonephritis 10.1
23 ossifying fibroma 10.1 JAG1 NOTCH1
24 lacrimal gland adenoid cystic carcinoma 10.1 NOTCH1 NOTCH2
25 cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1 10.0 JAG1 NOTCH1
26 connective tissue disease 10.0
27 banti's syndrome 10.0
28 leukemia 10.0
29 adenoma 10.0
30 vasculitis 10.0
31 membranous nephropathy 10.0
32 cholestasis 10.0
33 myasthenia gravis congenital 10.0
34 rheumatoid vasculitis 10.0
35 myasthenia gravis 10.0
36 macroglobulinemia 10.0
37 arthritis 10.0
38 thrombosis 10.0
39 crohn's disease 10.0
40 pancreatitis 10.0
41 lung adenoma 10.0 NOTCH1 NOTCH2
42 thiopurines, poor metabolism of, 1 10.0 ITPA TPMT
43 tricuspid valve stenosis 9.9 JAG1 NOTCH1
44 pulmonary hypertension, primary, 1 9.9
45 autoimmune disease 1 9.9
46 esophageal varix 9.9
47 rheumatoid arthritis 9.9
48 aplastic anemia 9.9
49 portal vein thrombosis 9.9
50 carcinoid syndrome 9.9

Graphical network of the top 20 diseases related to Nodular Regenerative Hyperplasia:



Diseases related to Nodular Regenerative Hyperplasia
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Symptoms & Phenotypes for Nodular Regenerative Hyperplasia

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Human phenotypes related to Nodular Regenerative Hyperplasia:

59 32
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 portal hypertension 59 32 occasional (7.5%) Occasional (29-5%) HP:0001409
2 abnormality of the hepatic vasculature 59 Very frequent (99-80%)

MGI Mouse Phenotypes related to Nodular Regenerative Hyperplasia:

46 (show all 13)
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.13 NOTCH2 NOTCH1 GFER EFNB2 ITPA PCNA
2 hematopoietic system MP:0005397 10.06 NOTCH2 NOTCH1 EFNB2 ITPA PCNA TPMT
3 cellular MP:0005384 10.05 NOTCH2 NOTCH1 GFER EFNB2 ITPA JAG1
4 mortality/aging MP:0010768 10.02 NOTCH2 NOTCH1 GFER EFNB2 ITPA PCNA
5 cardiovascular system MP:0005385 10 F3 NOTCH2 EFNB2 ITPA NOTCH1 JAG1
6 homeostasis/metabolism MP:0005376 9.98 F3 GFER NOTCH2 EFNB2 TPMT NOTCH1
7 embryo MP:0005380 9.89 JAG1 F3 NOTCH2 EFNB2 NOTCH1
8 integument MP:0010771 9.88 NOTCH2 NOTCH1 EFNB2 ITPA JAG1 F3
9 muscle MP:0005369 9.8 NOTCH2 NOTCH1 EFNB2 ITPA JAG1 F3
10 neoplasm MP:0002006 9.56 NOTCH1 F3 GFER NOTCH2
11 normal MP:0002873 9.55 NOTCH1 JAG1 F3 NOTCH2 EFNB2
12 respiratory system MP:0005388 9.35 F3 NOTCH2 NOTCH1 EFNB2 ITPA
13 vision/eye MP:0005391 9.02 F3 NOTCH2 EFNB2 NOTCH1 JAG1
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Drugs & Therapeutics for Nodular Regenerative Hyperplasia

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Drugs for Nodular Regenerative Hyperplasia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 53)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Caffeine Approved, Nutraceutical Phase 4 58-08-2 2519
2 Mesalamine Phase 4 89-57-6
3 Analgesics Phase 4
4 Analgesics, Non-Narcotic Phase 4
5 Peripheral Nervous System Agents Phase 4,Not Applicable
6 Anti-Inflammatory Agents Phase 4
7 Anti-Inflammatory Agents, Non-Steroidal Phase 4
8 Antirheumatic Agents Phase 4
9 Calcium, Dietary Phase 4
10 Calcium Supplement Nutraceutical Phase 4
11
Propranolol Approved, Investigational Phase 3 525-66-6 4946
12 Adrenergic Agents Phase 3,Not Applicable
13 Adrenergic Antagonists Phase 3
14 Adrenergic beta-Antagonists Phase 3
15 Neurotransmitter Agents Phase 3,Not Applicable
16 Anti-Arrhythmia Agents Phase 3
17 Vasodilator Agents Phase 3
18 Antihypertensive Agents Phase 3
19
Epinephrine Approved, Vet_approved Not Applicable 51-43-4 5816
20
Racepinephrine Approved Not Applicable 329-65-7 838
21
Doxorubicin Approved, Investigational 23214-92-8 31703
22
Ifosfamide Approved 3778-73-2 3690
23
Vincristine Approved, Investigational 2068-78-2, 57-22-7 5978
24
Cyclophosphamide Approved, Investigational 50-18-0, 6055-19-2 2907
25
Dactinomycin Approved, Investigational 50-76-0 2019 457193
26
Etomidate Approved Not Applicable 33125-97-2 36339 667484
27
Formaldehyde Approved, Vet_approved 50-00-0 712
28
Doxil Approved June 1999 31703
29 glucocorticoids Not Applicable
30 Hormone Antagonists Not Applicable
31 Hormones Not Applicable
32 Hormones, Hormone Substitutes, and Hormone Antagonists Not Applicable
33 Epinephryl borate Not Applicable
34 Liver Extracts ,Not Applicable
35
Isophosphamide mustard 0
36 Coagulants Not Applicable
37 Hematinics Not Applicable
38 Hemostatics Not Applicable
39 Respiratory System Agents Not Applicable
40 Central Nervous System Depressants Not Applicable
41 Adrenergic Agonists Not Applicable
42 Adrenergic alpha-Agonists Not Applicable
43 Adrenergic beta-Agonists Not Applicable
44 Mydriatics Not Applicable
45 Anesthetics Not Applicable
46 Anesthetics, General Not Applicable
47 Anesthetics, Intravenous Not Applicable
48 Vasoconstrictor Agents Not Applicable
49 Anti-Asthmatic Agents Not Applicable
50 Hypnotics and Sedatives Not Applicable

Interventional clinical trials:

(show all 19)
# Name Status NCT ID Phase Drugs
1 Clinical Management of Childhood Intestinal Lymphoid Nodular Hyperplasia Unknown status NCT01789294 Phase 4 Mesalamine
2 Comparison of Endoscopic Variceal Ligation (EVL) With Propranolol in Non Cirrhotic Portal Hypertension (NCPH) Completed NCT01000779 Phase 3 Propranolol
3 Contrast Enhanced Ultrasound For The Evaluation Of Focal Liver Lesions Unknown status NCT01329458
4 Mutations of Glucocorticoid Receptor in Bilateral Adrenal Hyperplasia Unknown status NCT02810496 Not Applicable
5 Risk Factors for Variceal Bleeding in Egyptian Patients With Non-Cirrhotic Portal Hypertension Completed NCT02635815
6 Quantitative Real-time Ultrasound Elastography for Characterisation of Liver Tumors Completed NCT02156700
7 Configuration of a New Prostate Disease Nomogram Predicting Prostate Biopsy Outcome Completed NCT01826617
8 Contrast Enhanced (CE) Ultrasound and CE Computed Tomography or CE Magnetic Resonance Imaging in Liver Masses Completed NCT00828607
9 Superb Microvascular Imaging in Focal Nodular Hyperplasia Recruiting NCT02737865 Not Applicable Sonazoid
10 Natural History of Noncirrhotic Portal Hypertension Recruiting NCT02417740
11 Efficacy and Tolerability of Hemopatch After Hepatic Resection Recruiting NCT03323359 Not Applicable
12 Vienna Vascular Liver Disease Study Recruiting NCT03541057
13 International PPB Registry for PPB, DICER1 and Associated Conditions Recruiting NCT03382158
14 Comparison of Hydro-dissection Versus Ultrasonic Aspirator in Division of Liver Parenchyma in Laparoscopic Resection Recruiting NCT03208192 Not Applicable
15 Evaluation of Patients With Liver Disease Recruiting NCT00001971
16 A Nation-wide Hospital-based Hepatitis B Registry:China Registry of Hepatitis B Recruiting NCT03108794
17 11C-Metomidate PET Versus Adrenal Vein Sampling in Primary Aldosteronism Active, not recruiting NCT01567111 Not Applicable
18 Evaluation of Gastroesophageal Varices by Transnasal Endoscopy. Enrolling by invitation NCT02767206
19 Expression of Protein Convertases in Thyroid Nodules Enrolling by invitation NCT03160482

Search NIH Clinical Center for Nodular Regenerative Hyperplasia

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Genetic Tests for Nodular Regenerative Hyperplasia

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Anatomical Context for Nodular Regenerative Hyperplasia

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MalaCards organs/tissues related to Nodular Regenerative Hyperplasia:

41
Liver, Bone Marrow, Bone, Kidney, Prostate, Thyroid, T Cells
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Publications for Nodular Regenerative Hyperplasia

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Articles related to Nodular Regenerative Hyperplasia:

(show top 50) (show all 247)
# Title Authors Year
1
Novel IL2RG Mutation Causes Leaky TLOWB+NK+ SCID With Nodular Regenerative Hyperplasia and Normal IL-15 STAT5 Phosphorylation. ( 29939941 )
2018
2
Nodular Regenerative Hyperplasia of the Liver: A Rare Vascular Complication in Systemic Sclerosis. ( 29093156 )
2018
3
Clinical Course of Nodular Regenerative Hyperplasia in Thiopurine Treated Inflammatory Bowel Disease Patients. ( 29775790 )
2018
4
Nodular regenerative hyperplasia rarely leads to liver transplantation: A 20-year cohort study in all Dutch liver transplant units. ( 28815029 )
2017
5
Nodular Regenerative Hyperplasia: A Case of Rare Prognosis. ( 28491877 )
2017
6
A Rare Cause of Portal Hypertension: Behcet's Disease and Nodular Regenerative Hyperplasia of the Liver. ( 28465872 )
2017
7
Nodular Regenerative Hyperplasia of the Liver in Patients with IBD Treated with Allopurinol-Thiopurine Combination Therapy. ( 28151736 )
2017
8
Nodular Regenerative Hyperplasia in HIV-positive patients : a case series and review of the literature. ( 29364092 )
2017
9
Epigastric Pain in a Patient With Nodular Regenerative Hyperplasia. ( 26827806 )
2016
10
Ataxia telangiectasia associated with nodular regenerative hyperplasia. ( 27671921 )
2016
11
A case of idiopathic portal hypertension associated with nodular regenerative hyperplasia-like nodule of the liver and mixed connective tissue disease. ( 27151480 )
2016
12
The Prevalence of Nodular Regenerative Hyperplasia in Inflammatory Bowel Disease Patients Treated with Thioguanine Is Not Associated with Clinically Significant Liver Disease. ( 27482972 )
2016
13
P437. Short term prevalence of nodular regenerative hyperplasia of the liver in IBD patients treated with allopurinol-thiopurine combination therapy. ( 25717925 )
2015
14
Prevalence and clinical significance of nodular regenerative hyperplasia in liver biopsies. ( 26415006 )
2015
15
Diagnosing Nodular Regenerative Hyperplasia of the Liver Is Thwarted by Low Interobserver Agreement. ( 26054009 )
2015
16
Development of nodular regenerative hyperplasia (NRH) with portal hypertension following the administration of oxaliplatin for the recurrence of colon cancer. ( 25748953 )
2015
17
Nodular Regenerative Hyperplasia after Liver Transplantation Complicated with Inferior Vena Cava Stenosis: a Clue for Etiopathogenesis? ( 26405712 )
2015
18
Hepatic Lesions Caused by Large Granular Lymphocyte Leukemia in Fischer 344 Rats: Similar Morphologic Features and Morphogenesis to Those of Nodular Regenerative Hyperplasia (NRH) in the Human Liver. ( 25903270 )
2015
19
Indolent cytotoxic T cell lymphoproliferation associated with nodular regenerative hyperplasia: a common liver lesion in the context of common variable immunodeficiency disorder. ( 26493984 )
2015
20
A case of nodular regenerative hyperplasia of the liver combined with toxic hepatitis. ( 25603855 )
2015
21
Nodular Regenerative Hyperplasia in Patients Undergoing Liver Resection for Colorectal Metastases After Chemotherapy: Risk Factors, Preoperative Assessment and Clinical Impact. ( 25845431 )
2015
22
Hepatocellular carcinoma and nodular regenerative hyperplasia after chemotherapy for metastatic colorectal carcinoma. ( 24604623 )
2014
23
Nodular Regenerative Hyperplasia After Treatment With Trastuzumab Emtansine. ( 24778392 )
2014
24
Nodular regenerative hyperplasia of the liver and cutaneous T-cell lymphoma: an unreported association. ( 25075662 )
2014
25
Concurrent liver hodgkin lymphoma and nodular regenerative hyperplasia on an explanted liver with clinical diagnosis of alcoholic cirrhosis at university hospital fundaciA^n santa fe de bogotA!. ( 24511402 )
2014
26
Nodular Regenerative Hyperplasia Causing Portal Hypertension in a Patient with Chronic Graft versus Host Disease: Response to Sirolimus. ( 24434665 )
2014
27
Human immunodeficiency virus and nodular regenerative hyperplasia of liver: A systematic review. ( 24653794 )
2014
28
Hepatopulmonary syndrome associated with nodular regenerative hyperplasia after liver transplantation in a child. ( 24820314 )
2014
29
Splenic artery ligation for severe oxaliplatin induced portal hypertension: a way to improve postoperative course and allow adjuvant chemotherapy for colorectal liver metastases.: Letter to editor: comment about "Nodular regenerative hyperplasia (NRH) complicating oxaliplatin chemotherapy in patients undergoing resection of colorectal liver metastases". ( 24613742 )
2014
30
Drug-induced nodular regenerative hyperplasia. ( 24879987 )
2014
31
Nodular regenerative hyperplasia in a patient with generalized essential telangiectasia: Endotheliopathy as causal factor. ( 24273032 )
2013
32
Nodular regenerative hyperplasia related portal hypertension in a patient with hypogammaglobulinaemia. ( 23801845 )
2013
33
Portal Hypertension, Nodular Regenerative Hyperplasia of the Liver, and Obstructive Portal Venopathy due to Metastatic Breast Cancer. ( 23984149 )
2013
34
Hepatoportal sclerosis (obliterative portal venopathy) and nodular regenerative hyperplasia in a patient with myasthenia gravis: A case report and review of the published work. ( 23675894 )
2013
35
Nodular regenerative hyperplasia in common variable immunodeficiency. ( 23420139 )
2013
36
Unusual Nodular Regenerative Hyperplasia Mimicking Liver Metastases in CEUS. ( 24327467 )
2013
37
Nodular regenerative hyperplasia (NRH) complicating oxaliplatin chemotherapy in patients undergoing resection of colorectal liver metastases. ( 24370284 )
2013
38
Nodular regenerative hyperplasia of the liver as a complication of long-standing systemic-onset juvenile idiopathic arthritis. ( 24315465 )
2013
39
Patients with nodular regenerative hyperplasia should be considered for hepatocellular carcinoma screening. ( 23607291 )
2013
40
Familial occurrence of nodular regenerative hyperplasia of the liver. ( 23287953 )
2013
41
Downregulation of the Endothelial Genes Notch1 and EphrinB2 in Patients with Nodular Regenerative Hyperplasia. ( 23870033 )
2013
42
Review article: the association between nodular regenerative hyperplasia, inflammatory bowel disease and thiopurine therapy. ( 24099468 )
2013
43
Lengthy follow-up after liver transplantation for nodular regenerative hyperplasia in human immunodeficiency virus-infected patients: does the disease recur? ( 24296606 )
2013
44
Clinical analysis of 15 cases of liver nodular regenerative hyperplasia. ( 22707296 )
2012
45
Portal hypertension in nodular regenerative hyperplasia: a mixed bag! ( 22823913 )
2012
46
Nodular regenerative hyperplasia of the liver and portal thrombosis. ( 22880521 )
2012
47
Noncirrhotic Portal Hypertension due to Nodular Regenerative Hyperplasia Treated with Surgical Portacaval Shunt. ( 22956964 )
2012
48
Hepatic hemodynamics in 24 patients with nodular regenerative hyperplasia and symptomatic portal hypertension. ( 22554152 )
2012
49
Interstitial pneumonia and nodular regenerative hyperplasia of the liver as initial manifestations of polyarteritis nodosa. ( 22449674 )
2012
50
Diffuse Muscular Pain, Skin Tightening, and Nodular Regenerative Hyperplasia Revealing Paraneoplastic Amyopathic Dermatomyositis due to Testicular Cancer. ( 23316407 )
2012
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Variations for Nodular Regenerative Hyperplasia

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Expression for Nodular Regenerative Hyperplasia

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Search GEO for disease gene expression data for Nodular Regenerative Hyperplasia.
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Pathways for Nodular Regenerative Hyperplasia

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Pathways related to Nodular Regenerative Hyperplasia according to GeneCards Suite gene sharing:

(show all 12)
# Super pathways Score Top Affiliating Genes
1
Notch signaling pathway (KEGG) 1
Show member pathways
 12.23 JAG1 NOTCH1 NOTCH2
2
Th17 cell differentiation 37
Show member pathways
 12.07 JAG1 NOTCH1 NOTCH2
3
Wnt / Hedgehog / Notch 4
11.84 JAG1 NOTCH1 NOTCH2
4
NOTCH2 Activation and Transmission of Signal to the Nucleus 66
Show member pathways
 11.59 JAG1 NOTCH1 NOTCH2
5
Primary Focal Segmental Glomerulosclerosis FSGS 1
11.2 JAG1 NOTCH1 PCNA
6
Th2 Differentiation Pathway 65
11.16 JAG1 NOTCH1
7
Notch Signaling Pathway (sino) 67
11 NOTCH1 NOTCH2
8
Angiogenesis (CST) 4
10.97 EFNB2 F3 JAG1 NOTCH1 NOTCH2
9
Thiopurine Pathway, Pharmacokinetics/Pharmacodynamics 61
10.86 ITPA TPMT
10
NOTCH1 regulation of human endothelial cell calcification 1
10.62 JAG1 NOTCH1
11
Canonical and Non-canonical Notch signaling 1
10.56 JAG1 NOTCH1 NOTCH2
12
Amplification and Expansion of Oncogenic Pathways as Metastatic Traits 1
10.55 JAG1 NOTCH1
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GO Terms for Nodular Regenerative Hyperplasia

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Biological processes related to Nodular Regenerative Hyperplasia according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 animal organ morphogenesis GO:0009887 9.67 EFNB2 JAG1 NOTCH2
2 Notch signaling pathway GO:0007219 9.63 JAG1 NOTCH1 NOTCH2
3 negative regulation of cell differentiation GO:0045596 9.58 JAG1 NOTCH1
4 negative regulation of neuron differentiation GO:0045665 9.57 JAG1 NOTCH1
5 positive regulation of Notch signaling pathway GO:0045747 9.56 JAG1 NOTCH1
6 neuronal stem cell population maintenance GO:0097150 9.55 JAG1 NOTCH1
7 positive regulation of Ras protein signal transduction GO:0046579 9.54 NOTCH1 NOTCH2
8 cell fate determination GO:0001709 9.52 JAG1 NOTCH2
9 negative regulation of stem cell differentiation GO:2000737 9.51 JAG1 NOTCH1
10 response to muramyl dipeptide GO:0032495 9.48 JAG1 NOTCH1
11 cardiac septum morphogenesis GO:0060411 9.43 JAG1 NOTCH1
12 venous blood vessel morphogenesis GO:0048845 9.4 EFNB2 NOTCH1
13 regulation of developmental process GO:0050793 9.37 NOTCH1 NOTCH2
14 distal tubule development GO:0072017 9.32 JAG1 NOTCH1
15 positive regulation of aorta morphogenesis GO:1903849 9.26 EFNB2 NOTCH1
16 negative regulation of growth rate GO:0045967 9.16 NOTCH1 NOTCH2
17 pulmonary valve morphogenesis GO:0003184 9.13 JAG1 NOTCH1 NOTCH2
18 Notch signaling involved in heart development GO:0061314 8.8 JAG1 NOTCH1 NOTCH2

Molecular functions related to Nodular Regenerative Hyperplasia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Notch binding GO:0005112 8.62 JAG1 NOTCH1
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Sources for Nodular Regenerative Hyperplasia

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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