NOMA
MCID: NM001
MIFTS: 42

Noma (NOMA)

Categories: Infectious diseases, Oral diseases, Rare diseases

Aliases & Classifications for Noma

MalaCards integrated aliases for Noma:

Name: Noma 12 75 53 59 44 15 17 72
Cancrum Oris 12 53 59
Oro-Facial Gangrene 53 72
Gangrenous Stomatitis 12
Noma Neonatorum 53
Oro-Facial Noma 53
Oral Gangrene 53

Characteristics:

Orphanet epidemiological data:

59
noma
Age of onset: Childhood;

Classifications:

Orphanet: 59  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:9672
ICD9CM 35 528.1
MeSH 44 D009625
NCIt 50 C34852
SNOMED-CT 68 18116006
ICD10 33 A69.0
MESH via Orphanet 45 D009625
ICD10 via Orphanet 34 A69.0
UMLS via Orphanet 73 C0028271
Orphanet 59 ORPHA2700
UMLS 72 C0028271 C2930832

Summaries for Noma

MalaCards based summary : Noma, also known as cancrum oris, is related to acatalasemia and stomatitis, and has symptoms including oral manifestations An important gene associated with Noma is ARHGAP33 (Rho GTPase Activating Protein 33), and among its related pathways/superpathways are Akt Signaling and TGF-Beta Pathway. Affiliated tissues include breast, bone and liver, and related phenotypes are homeostasis/metabolism and cellular

Wikipedia : 75 Noma or (also known as cancrum oris) is a rapidly progressive often gangrenous infection of the mouth... more...

Related Diseases for Noma

Diseases related to Noma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 101)
# Related Disease Score Top Affiliating Genes
1 acatalasemia 11.8
2 stomatitis 10.7
3 gingivitis 10.6
4 measles 10.6
5 african histoplasmosis 10.5 RHNO1 ALB
6 pyuria 10.5 CXCL8 ALB
7 ankylosis 10.4
8 acute cystitis 10.4 IL18 CXCL8 ALB
9 extrinsic allergic alveolitis 10.4 IL18 CXCL8 ALB
10 proteasome-associated autoinflammatory syndrome 1 10.3 IL18 CXCL8 ALB
11 necrotizing ulcerative gingivitis 10.3
12 fasciitis 10.3
13 upper respiratory tract disease 10.3 RHNO1 CXCL8 ALB
14 cerebrovascular disease 10.3
15 necrotizing fasciitis 10.3
16 ulcerative stomatitis 10.3
17 immune deficiency disease 10.2
18 neutropenia 10.2
19 myositis 10.2
20 down syndrome 10.2
21 dysentery 10.2
22 typhoid fever 10.2
23 myositis ossificans 10.2
24 granulocytopenia 10.2
25 posttransplant acute limbic encephalitis 10.2
26 overgrowth syndrome 10.2
27 bacterial infectious disease 10.2
28 ecthyma 10.2
29 leukemia 10.2
30 acquired immunodeficiency syndrome 10.2
31 chronic kidney disease 10.2
32 generalized resistance to thyroid hormone 10.2 TRH PRL
33 adenohypophysitis 10.1 TRH PRL
34 pseudohypoparathyroidism, type ia 10.1 TRH PRL
35 atherosclerosis susceptibility 10.1
36 cyclic neutropenia 10.1
37 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.1
38 osteonecrosis 10.1
39 diarrhea 10.1
40 kwashiorkor 10.1
41 vascular disease 10.1
42 kidney disease 10.1
43 gas gangrene 10.1
44 cytokine deficiency 10.1
45 lymphosarcoma 10.1
46 sapho syndrome 10.0 IL18 CXCL8
47 diffuse glomerulonephritis 10.0 FGF2 ALB
48 burkitt lymphoma 9.9
49 migraine with or without aura 1 9.9
50 autism 9.9

Graphical network of the top 20 diseases related to Noma:



Diseases related to Noma

Symptoms & Phenotypes for Noma

UMLS symptoms related to Noma:


oral manifestations

MGI Mouse Phenotypes related to Noma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.15 ALB ARHGAP1 FGF2 IL18 MAPK7 NGFR
2 cellular MP:0005384 10.1 ALB ARHGAP1 FGF2 IL18 MAPK7 NGFR
3 integument MP:0010771 9.97 ARHGAP1 IL18 MAPK7 NGFR NME1 PGR
4 liver/biliary system MP:0005370 9.86 ALB ARHGAP1 NGFR NME1 PRL PTN
5 muscle MP:0005369 9.81 ALB ARHGAP1 FGF2 IL18 MAPK7 NGFR
6 neoplasm MP:0002006 9.5 ALB FGF2 NME1 PGR PRL PTPN11
7 nervous system MP:0003631 9.4 ARHGAP1 ARHGAP33 FGF2 IL18 MAPK7 NGFR

Drugs & Therapeutics for Noma

Cochrane evidence based reviews: noma

Genetic Tests for Noma

Anatomical Context for Noma

MalaCards organs/tissues related to Noma:

41
Breast, Bone, Liver, Lung, Skin, Testes, T Cells

Publications for Noma

Articles related to Noma:

(show top 50) (show all 574)
# Title Authors PMID Year
1
Inclusion of Real-Time Hand Hygiene Observation and Feedback in a Multimodal Hand Hygiene Improvement Strategy in Low-Resource Settings. 38
31411711 2019
2
On the Performance of Energy Harvesting Non-Orthogonal Multiple Access Relaying System with Imperfect Channel State Information over Rayleigh Fading Channels. 38
31362403 2019
3
Genetic diversity and relationships among native Japanese horse breeds, the Japanese Thoroughbred and horses outside of Japan using genome-wide SNP data. 38
31282588 2019
4
Noma-knowledge and practice competence among primary healthcare workers: a cross-sectional study in Burkina Faso. 38
30561632 2019
5
Estimated incidence and Prevalence of noma in north central Nigeria, 2010-2018: A retrospective study. 38
31329580 2019
6
On Exact Outage and Throughput Performance of Cognitive Radio based Non-Orthogonal Multiple Access Networks With and Without D2D Link. 38
31357691 2019
7
A Deep Learning Approach for MIMO-NOMA Downlink Signal Detection. 38
31159505 2019
8
Noma (cancrum oris): An unresolved global challenge. 38
31090145 2019
9
Noma in a boy with septic shock: a case report. 38
31208399 2019
10
Noma: a reappraisal in Western countries - are HIV-negative immunocompetent adult patients safe? 38
31184103 2019
11
HD/FD and DF/AF with Fixed-Gain or Variable-Gain Protocol Switching Mechanism over Cooperative NOMA for Green-Wireless Networks. 38
31003436 2019
12
A Novel Four Single-Sideband M-QAM Modulation Scheme Using a Shadow Equalizer for MIMO System Toward 5G Communications. 38
31027234 2019
13
Radio Resource Allocation with The Fairness Metric for Low Density Signature OFDM in Underlay Cognitive Radio Networks. 38
31018612 2019
14
Infantile and adult mortality in precarious conditions. 38
31035021 2019
15
Novel SWIPT Schemes for 5G Wireless Networks. 38
30866552 2019
16
Exploiting Impact of Hardware Impairments in NOMA: Adaptive Transmission Mode in FD/HD and Application in Internet-of-Things. 38
30875822 2019
17
Uplink Non-Orthogonal Multiple Access with Channel Estimation Errors for Internet of Things Applications. 38
30795604 2019
18
Outage Performance Analysis and SWIPT Optimization in Energy-Harvesting Wireless Sensor Network Deploying NOMA. 38
30717155 2019
19
NOMA-Assisted Multiple Access Scheme for IoT Deployment: Relay Selection Model and Secrecy Performance Improvement. 38
30759775 2019
20
Pattern of noma (cancrum oris) and its risk factors in Northwestern Nigeria: A hospital-based retrospective study. 38
30729928 2019
21
Underestimation of breast cancer in intraductal papillomas treated with vacuum-assisted core needle biopsy. 38
30950000 2019
22
Noma surgery. 38
30194753 2019
23
Noma Neonatorum: A Disease Long Forgotten. 38
30550012 2018
24
The surgical management of extra-articular ankylosis in noma patients. 38
30104131 2018
25
Secure and private NOMA VLC using OFDM with two-level chaotic encryption. 38
30650833 2018
26
Performance improvement of NOMA visible light communication system by adjusting superposition constellation: a convex optimization approach. 38
30469938 2018
27
Application of NOMA in Wireless System with Wireless Power Transfer Scheme: Outage and Ergodic Capacity Performance Analysis. 38
30336586 2018
28
Digital Domain Power Division Multiplexed Dual Polarization Coherent Optical OFDM Transmission. 38
30361554 2018
29
Multi-cell coordination for 60 GHz RoF fronthaul enabled by a non-orthogonal multiple access scheme without successive interference cancellation. 38
30160760 2018
30
Multi-user access in wireless optical communication system. 38
30184923 2018
31
RF Energy Harvesting and Information Transmission Based on NOMA for Wireless Powered IoT Relay Systems. 38
30262773 2018
32
Optimal Resource Allocation for Uplink Data Collection in Nonorthogonal Multiple Access Networks. 38
30081488 2018
33
Risk factors for diagnosed noma in northwest Nigeria: A case-control study, 2017. 38
30138374 2018
34
Evaluation of the Noma Disease Burden Within the Noma Belt. 38
29800992 2018
35
An unusual case of noma caused by Klebsiella pnuemoniae and its management. 38
29368993 2018
36
Fast Convolution Filter-Bank Based Non-Orthogonal Multiplexed Cognitive Radio (NOMCR) Receiver Design Using Cyclostationarity Based FRESH Filtering. 38
29899317 2018
37
Optimal Resource Allocation for NOMA-TDMA Scheme with α-Fairness in Industrial Internet of Things. 38
29762506 2018
38
The Progress on Noma Disease and Its Surgical Treatment. 38
29538189 2018
39
Cancrum oris (noma): An early sign of acute lymphoblastic leukemia relapse. 38
28799529 2018
40
Evaluation of Hemoglobin Concentration and Hematocrit Values in Temporomandibular Joint Ankylosis Patients in Comparison to Nonankylosed Patients. 38
29422472 2018
41
Non-Orthogonal Multiple Access for Ubiquitous Wireless Sensor Networks. 38
29419795 2018
42
Tumor-infiltrating lymphocytes are associated with β-catenin overexpression in breast cancer. 38
29286921 2018
43
Rate-splitting multiple access for downlink communication systems: bridging, generalizing, and outperforming SDMA and NOMA. 38
30996723 2018
44
Ecthyma gangrenosum on the face of a malnourished child with Pseudomonas sepsis: Simulating Cancrum oris. 38
30568894 2018
45
A progressive ulcer in immunocompetent man: cancrum oris. 38
28541141 2018
46
Noma in an HIV infected patient in Guinea-Bissau: a case report. 38
28589415 2017
47
Complete Lower Lip Reconstruction with a Large Lip Switch Flap and a Composite Modiolus Advancement Flap. 38
29632785 2017
48
Zinc oxide nanoparticle toxicity in embryonic zebrafish: Mitigation with different natural organic matter. 38
28841783 2017
49
Solution for error propagation in a NOMA-based VLC network: symmetric superposition coding. 38
29221021 2017
50
Power Allocation Scheme for Non-Orthogonal Multiple Access in Underwater Acoustic Communications. 38
29076999 2017

Variations for Noma

Expression for Noma

Search GEO for disease gene expression data for Noma.

Pathways for Noma

Pathways related to Noma according to GeneCards Suite gene sharing:

(show all 19)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.22 TNFRSF1A PTN NGFR IL18 FGF2 CXCL8
2
Show member pathways
13.09 TNFRSF1A PTPN11 PTN PRL NGFR MAPK7
3
Show member pathways
12.67 TNFRSF1A PTPN11 PTN NGFR MAPK7 IL18
4 12.54 TNFRSF1A NGFR MAPK7 FGF2 CDC42
5
Show member pathways
12.18 NGFR FGF2 CDC42 ARHGAP1
6
Show member pathways
11.94 PTPN11 PTN NGFR IL18 FGF2 CXCL8
7 11.84 NGFR CXCL8 CDC42
8 11.83 PTPN11 NGFR MAPK7 CDC42
9 11.81 IL18 FGF2 CXCL8
10 11.8 PTPN11 MAPK7 CDC42
11 11.6 IL18 CXCL8 CDC42
12 11.54 PTN MAPK7 FGF2 ARHGAP1
13
Show member pathways
11.42 PTPN11 NGFR CDC42
14 11.3 TNFRSF1A IL18 CXCL8
15
Show member pathways
11.18 TNFRSF1A PTPN11 PTN NGFR IL18 FGF2
16 10.97 NME1 CDC42 ARHGAP1
17 10.85 NGFR FGF2 CDC42 ARHGAP1
18 10.84 PTN IL18 FGF2 CXCL8 CDC42
19 10.79 PTN CXCL8

GO Terms for Noma

Cellular components related to Noma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.28 TRH TNFRSF1A PTN PRL NGFR IL18
2 secretory granule GO:0030141 8.96 TRH CDC42

Biological processes related to Noma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 9.81 TRH TNFRSF1A PGR NGFR MAPK7 FGF2
2 nervous system development GO:0007399 9.8 PTN NME1 NGFR FGF2 CDC42
3 small GTPase mediated signal transduction GO:0007264 9.63 CDC42 ARHGAP33 ARHGAP1
4 Rho protein signal transduction GO:0007266 9.54 NGFR CDC42 ARHGAP1
5 neutrophil activation GO:0042119 9.43 IL18 CXCL8
6 paracrine signaling GO:0038001 9.32 PGR FGF2
7 wybutosine biosynthetic process GO:0031591 9.26 TYW3 TRMT12
8 mammary gland development GO:0030879 9.13 PRL PGR NME1
9 cytokine-mediated signaling pathway GO:0019221 9.02 TNFRSF1A PTPN11 IL18 FGF2 CXCL8

Molecular functions related to Noma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.86 TRMT12 TNFRSF1A RHNO1 PTPN11 PRL PGR
2 tRNA methyltransferase activity GO:0008175 8.62 TYW3 TRMT12

Sources for Noma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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