MCID: NNG002
MIFTS: 26

Non-Gestational Ovarian Choriocarcinoma

Categories: Cancer diseases, Endocrine diseases, Fetal diseases, Reproductive diseases

Aliases & Classifications for Non-Gestational Ovarian Choriocarcinoma

MalaCards integrated aliases for Non-Gestational Ovarian Choriocarcinoma:

Name: Non-Gestational Ovarian Choriocarcinoma 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:7665
NCIt 51 C39991
UMLS 74 C1518355

Summaries for Non-Gestational Ovarian Choriocarcinoma

Disease Ontology : 12 An ovarian primitive germ cell tumor that has material basis in trophoblastic cells and develops in the absence of a preceding gestational event.

MalaCards based summary : Non-Gestational Ovarian Choriocarcinoma is related to choriocarcinoma of ovary and primary non-gestational choriocarcinoma of ovary. An important gene associated with Non-Gestational Ovarian Choriocarcinoma is TEK (TEK Receptor Tyrosine Kinase), and among its related pathways/superpathways are Innate Immune System and PI3K-Akt signaling pathway. Affiliated tissues include ovary, brain and pituitary, and related phenotype is nervous system.

Related Diseases for Non-Gestational Ovarian Choriocarcinoma

Diseases related to Non-Gestational Ovarian Choriocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 33)
# Related Disease Score Top Affiliating Genes
1 choriocarcinoma of ovary 30.1 NCAM1 PRL TEK
2 primary non-gestational choriocarcinoma of ovary 11.9
3 choriocarcinoma 10.6
4 gestational ovarian choriocarcinoma 10.6
5 prolactin producing pituitary tumor 10.0 PRL TP53
6 granulosa cell tumor of the ovary 10.0 PRL TP53
7 chromophobe adenoma 10.0 PRL TP53
8 adenoma 10.0 PRL TP53
9 cell type benign neoplasm 10.0 PRL TP53
10 female reproductive system disease 10.0 PRL TP53
11 reproductive system disease 9.9 PRL TP53
12 gonadal disease 9.9 PRL TP53
13 ovarian disease 9.9 PRL TP53
14 cervix small cell carcinoma 9.9 NCAM1 TP53
15 small cell carcinoma 9.9 NCAM1 TP53
16 malignant mesenchymoma 9.9 NCAM1 TP53
17 hydrocephalus 9.9 PRL TP53
18 mature b-cell neoplasm 9.9 NCAM1 TP53
19 lung benign neoplasm 9.9 NCAM1 TP53
20 autonomic nervous system neoplasm 9.9 NCAM1 TP53
21 peripheral nervous system neoplasm 9.9 NCAM1 TP53
22 merkel cell carcinoma 9.8 NCAM1 TP53
23 leukocyte disease 9.8 NCAM1 TP53
24 adrenal rest tumor 9.8 NCAM1 PRL
25 bile duct cancer 9.8 NCAM1 TP53
26 small cell cancer of the lung 9.8 NCAM1 TP53
27 gastrointestinal stromal tumor 9.8 NCAM1 TP53
28 myeloma, multiple 9.7 NCAM1 TP53
29 diamond-blackfan anemia 9.7 PRL TP53
30 breast disease 9.7 PRL TEK TP53
31 muscular disease 9.7 NCAM1 TP53
32 cholangiocarcinoma 9.7 NCAM1 TP53
33 hematologic cancer 9.5 NCAM1 TP53

Graphical network of the top 20 diseases related to Non-Gestational Ovarian Choriocarcinoma:



Diseases related to Non-Gestational Ovarian Choriocarcinoma

Symptoms & Phenotypes for Non-Gestational Ovarian Choriocarcinoma

MGI Mouse Phenotypes related to Non-Gestational Ovarian Choriocarcinoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 8.92 NCAM1 PRL TEK TP53

Drugs & Therapeutics for Non-Gestational Ovarian Choriocarcinoma

Search Clinical Trials , NIH Clinical Center for Non-Gestational Ovarian Choriocarcinoma

Genetic Tests for Non-Gestational Ovarian Choriocarcinoma

Anatomical Context for Non-Gestational Ovarian Choriocarcinoma

MalaCards organs/tissues related to Non-Gestational Ovarian Choriocarcinoma:

42
Ovary, Brain, Pituitary, Cervix, B Cells

Publications for Non-Gestational Ovarian Choriocarcinoma

Articles related to Non-Gestational Ovarian Choriocarcinoma:

# Title Authors Year
1
Clinical and ultrasound features of non-gestational ovarian choriocarcinoma. ( 29080278 )
2018
2
Extremely Rare Case of Bilateral Pure Primary Non-Gestational Ovarian Choriocarcinoma. ( 29657619 )
2017
3
Clinicopathological analysis of non-gestational ovarian choriocarcinoma: Report of two cases and review of the literature. ( 27073524 )
2016
4
A pure non-gestational ovarian choriocarcinoma with delayed solitary brain metastases: Case report and review of the literature. ( 26752905 )
2015
5
Pure non-gestational ovarian choriocarcinoma in a 45,XO/46,XX SRY-negative true hermaphrodite. ( 22070612 )
2011
6
Pure primary non-gestational ovarian choriocarcinoma: a diagnostic dilemma. ( 20090265 )
2010
7
Management of non-gestational ovarian choriocarcinoma: laparoscopy can be essential. Report of two cases. ( 20561742 )
2010

Variations for Non-Gestational Ovarian Choriocarcinoma

Expression for Non-Gestational Ovarian Choriocarcinoma

Search GEO for disease gene expression data for Non-Gestational Ovarian Choriocarcinoma.

Pathways for Non-Gestational Ovarian Choriocarcinoma

Pathways related to Non-Gestational Ovarian Choriocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.22 NCAM1 PRL TEK TP53
2
Show member pathways
12.17 PRL TEK TP53
3
Show member pathways
12.03 NCAM1 PRL TEK TP53
4 11.41 TEK TP53
5 10.87 PRL TP53

GO Terms for Non-Gestational Ovarian Choriocarcinoma

Biological processes related to Non-Gestational Ovarian Choriocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 MAPK cascade GO:0000165 9.16 NCAM1 TEK
2 negative regulation of angiogenesis GO:0016525 8.96 PRL TEK
3 positive regulation of pri-miRNA transcription by RNA polymerase II GO:1902895 8.62 PRL TP53

Sources for Non-Gestational Ovarian Choriocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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