MCID: NNN005
MIFTS: 24

Non-Invasive Bladder Papillary Urothelial Neoplasm

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Non-Invasive Bladder Papillary Urothelial Neoplasm

MalaCards integrated aliases for Non-Invasive Bladder Papillary Urothelial Neoplasm:

Name: Non-Invasive Bladder Papillary Urothelial Neoplasm 12 15 74
Papillary Transitional Cell Neoplasm of Low Malignant Potential 74
Papillary Urothelial Neoplasm of Low Malignant Potential 12
Bladder Papillary Neoplasm of Low Malignant Potential 12
Bladder Punlmp 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6239

Summaries for Non-Invasive Bladder Papillary Urothelial Neoplasm

MalaCards based summary : Non-Invasive Bladder Papillary Urothelial Neoplasm, also known as papillary transitional cell neoplasm of low malignant potential, is related to papilloma and transitional cell carcinoma. An important gene associated with Non-Invasive Bladder Papillary Urothelial Neoplasm is FGFR3 (Fibroblast Growth Factor Receptor 3), and among its related pathways/superpathways are Central carbon metabolism in cancer and Bladder cancer. Related phenotype is renal/urinary system.

Wikipedia : 77 Papillary urothelial neoplasm of low malignant potential (PUNLMP) is an exophytic (outward growing),... more...

Related Diseases for Non-Invasive Bladder Papillary Urothelial Neoplasm

Graphical network of the top 20 diseases related to Non-Invasive Bladder Papillary Urothelial Neoplasm:



Diseases related to Non-Invasive Bladder Papillary Urothelial Neoplasm

Symptoms & Phenotypes for Non-Invasive Bladder Papillary Urothelial Neoplasm

MGI Mouse Phenotypes related to Non-Invasive Bladder Papillary Urothelial Neoplasm:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 8.92 BAG6 FGFR3 TP53 UPK3A

Drugs & Therapeutics for Non-Invasive Bladder Papillary Urothelial Neoplasm

Search Clinical Trials , NIH Clinical Center for Non-Invasive Bladder Papillary Urothelial Neoplasm

Genetic Tests for Non-Invasive Bladder Papillary Urothelial Neoplasm

Anatomical Context for Non-Invasive Bladder Papillary Urothelial Neoplasm

Publications for Non-Invasive Bladder Papillary Urothelial Neoplasm

Articles related to Non-Invasive Bladder Papillary Urothelial Neoplasm:

# Title Authors Year
1
Biological significance of TERT promoter mutation in papillary urothelial neoplasm of low malignant potential. ( 29193225 )
2018
2
Diagnostic difficulties in cases of papillary urothelial neoplasm of low malignant potential, urothelial proliferation of uncertain malignant potential, urothelial dysplasia and urothelial papilloma: A review of current literature. ( 29395466 )
2017
3
TERT Promoter Mutations Occur Frequently in Urothelial Papilloma and Papillary Urothelial Neoplasm of Low Malignant Potential. ( 28040359 )
2017
4
How to Name Papillary Tumors of the Bladder in Children: Transitional Cell Carcinoma or Papillary Urothelial Neoplasm of Low Malignant Potential? ( 26169007 )
2015
5
Loss of heterozygosity at 9q32-33 (DBC1 locus) in primary non-invasive papillary urothelial neoplasm of low malignant potential and low-grade urothelial carcinoma of the bladder and their associated normal urothelium. ( 18452128 )
2008
6
Concomitant carcinoid tumor and papillary urothelial neoplasm of low malignant potential in a patient with Crohn's disease: a case report. ( 18936711 )
2008

Variations for Non-Invasive Bladder Papillary Urothelial Neoplasm

Cosmic variations for Non-Invasive Bladder Papillary Urothelial Neoplasm:

9
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM483 HRAS urinary tract,bladder,other,neoplasm c.35G>T p.G12V 11:534288-534288 0
2 COSM499 HRAS urinary tract,bladder,other,neoplasm c.182A>G p.Q61R 11:533874-533874 0
3 COSM498 HRAS urinary tract,bladder,other,neoplasm c.182A>T p.Q61L 11:533874-533874 0
4 COSM496 HRAS urinary tract,bladder,other,neoplasm c.181C>A p.Q61K 11:533875-533875 0
5 COSM488 HRAS urinary tract,bladder,other,neoplasm c.37G>T p.G13C 11:534286-534286 0

Expression for Non-Invasive Bladder Papillary Urothelial Neoplasm

Search GEO for disease gene expression data for Non-Invasive Bladder Papillary Urothelial Neoplasm.

Pathways for Non-Invasive Bladder Papillary Urothelial Neoplasm

Pathways related to Non-Invasive Bladder Papillary Urothelial Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.77 FGFR3 TP53
2 10.66 FGFR3 TP53 UPK3A

GO Terms for Non-Invasive Bladder Papillary Urothelial Neoplasm

Biological processes related to Non-Invasive Bladder Papillary Urothelial Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 apoptotic process GO:0006915 9.43 BAG6 FGFR3 TP53
2 kidney development GO:0001822 9.16 BAG6 UPK3A
3 negative regulation of apoptotic process GO:0043066 8.96 BAG6 TP53
4 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0042771 8.62 BAG6 TP53

Sources for Non-Invasive Bladder Papillary Urothelial Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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