MCID: NNN005
MIFTS: 26

Non-Invasive Bladder Papillary Urothelial Neoplasm

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Non-Invasive Bladder Papillary Urothelial Neoplasm

MalaCards integrated aliases for Non-Invasive Bladder Papillary Urothelial Neoplasm:

Name: Non-Invasive Bladder Papillary Urothelial Neoplasm 12 15 70
Papillary Transitional Cell Neoplasm of Low Malignant Potential 70
Papillary Urothelial Neoplasm of Low Malignant Potential 12
Bladder Papillary Neoplasm of Low Malignant Potential 12
Bladder Punlmp 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6239
SNOMED-CT 67 128625004
UMLS 70 C1266010 C1518358

Summaries for Non-Invasive Bladder Papillary Urothelial Neoplasm

MalaCards based summary : Non-Invasive Bladder Papillary Urothelial Neoplasm, also known as papillary transitional cell neoplasm of low malignant potential, is related to papilloma and inverted papilloma. An important gene associated with Non-Invasive Bladder Papillary Urothelial Neoplasm is FGFR3 (Fibroblast Growth Factor Receptor 3), and among its related pathways/superpathways is Bladder cancer. Affiliated tissues include appendix, endothelial and lung.

Related Diseases for Non-Invasive Bladder Papillary Urothelial Neoplasm

Diseases related to Non-Invasive Bladder Papillary Urothelial Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 65)
# Related Disease Score Top Affiliating Genes
1 papilloma 30.9 TP53 KRT20 FGFR3
2 inverted papilloma 30.5 TP53 KRT20
3 transitional cell carcinoma 30.0 UPK3A TP53 KRT20 FGFR3 BRINP1
4 bladder papillary transitional cell neoplasm 29.0 ZKSCAN3 UPK3A TP53 SIGLEC12 KRT20 FGFR3
5 squamous cell papilloma 10.6
6 actinic cheilitis 10.3 TP53 FGFR3
7 cheilitis 10.3 TP53 FGFR3
8 multiple pterygium syndrome, lethal type 10.3
9 urinary tract infection 10.3
10 papillary carcinoma 10.3
11 crohn's disease 10.3
12 carcinoid syndrome 10.3
13 enterovesical fistula 10.3
14 acanthoma 10.2 TP53 FGFR3
15 chronic cervicitis 10.2 ZKSCAN3 TP53
16 clear cell adenocarcinoma 10.2 TP53 KRT20
17 t-cell adult acute lymphocytic leukemia 10.2 TP53 CNTN2
18 intratubular embryonal carcinoma 10.2 TP53 KRT20
19 eccrine sweat gland cancer 10.2 TP53 KRT20
20 sweat gland cancer 10.2 TP53 KRT20
21 clear cell basal cell carcinoma 10.2 TP53 KRT20
22 urethral benign neoplasm 10.2 TP53 KRT20
23 appendix disease 10.2 TP53 KRT20
24 peritoneal serous adenocarcinoma 10.2 TP53 KRT20
25 appendix cancer 10.2 TP53 KRT20
26 ureter, cancer of 10.2 NUMA1 FGFR3
27 bile duct adenoma 10.2 TP53 KRT20
28 urethra transitional cell carcinoma 10.2 UPK3A TP53
29 keratosis, seborrheic 10.2 TP53 FGFR3
30 ovarian benign neoplasm 10.1 TP53 KRT20
31 intrahepatic bile duct adenoma 10.1 TP53 KRT20
32 borst-jadassohn intraepidermal carcinoma 10.1 TP53 KRT20
33 invasive bladder transitional cell carcinoma 10.1 UPK3A TP53
34 duodenum cancer 10.1 TP53 KRT20
35 renal hypodysplasia/aplasia 3 10.1 UPK3A FGFR3
36 ureteral benign neoplasm 10.1 ZKSCAN3 UPK3A
37 papillary serous adenocarcinoma 10.1 TP53 KRT20
38 basaloid squamous cell carcinoma 10.1 TP53 KRT20
39 pseudomyxoma peritonei 10.1 TP53 KRT20
40 villous adenoma 10.1 TP53 KRT20
41 signet ring cell adenocarcinoma 10.1 TP53 KRT20
42 vulva adenocarcinoma 10.1 UPK3A KRT20
43 pyuria 10.1 UPK3A NUMA1
44 cystic teratoma 10.1 TP53 KRT20
45 ovarian brenner tumor 10.1 UPK3A KRT20
46 bladder transitional cell papilloma 10.1 TP53 KRT20 FGFR3
47 urethra clear cell adenocarcinoma 10.0 UPK3A KRT20
48 teratoma 10.0 TP53 KRT20 FGFR3
49 gallbladder adenocarcinoma 10.0 TP53 KRT20
50 bladder adenocarcinoma 10.0 UPK3A KRT20

Graphical network of the top 20 diseases related to Non-Invasive Bladder Papillary Urothelial Neoplasm:



Diseases related to Non-Invasive Bladder Papillary Urothelial Neoplasm

Symptoms & Phenotypes for Non-Invasive Bladder Papillary Urothelial Neoplasm

Drugs & Therapeutics for Non-Invasive Bladder Papillary Urothelial Neoplasm

Search Clinical Trials , NIH Clinical Center for Non-Invasive Bladder Papillary Urothelial Neoplasm

Genetic Tests for Non-Invasive Bladder Papillary Urothelial Neoplasm

Anatomical Context for Non-Invasive Bladder Papillary Urothelial Neoplasm

MalaCards organs/tissues related to Non-Invasive Bladder Papillary Urothelial Neoplasm:

40
Appendix, Endothelial, Lung

Publications for Non-Invasive Bladder Papillary Urothelial Neoplasm

Articles related to Non-Invasive Bladder Papillary Urothelial Neoplasm:

(show top 50) (show all 96)
# Title Authors PMID Year
1
Reappraisal of the papillary urothelial neoplasm of low malignant potential (PUNLMP). 61
32562556 2020
2
Papillary urothelial neoplasm of low malignant potential (PUN-LMP): Still a meaningful histo-pathological grade category for Ta, noninvasive bladder tumors in 2019? 61
31704141 2020
3
Clinicopathologic study of 60 cases of urothelial neoplasms with inverted growth patterns: Reclassification by international consultation on urologic disease (ICUD) recommendations. 61
31785538 2020
4
The Value of Preoperative Alpha-L-Fucosidase Levels in Evaluation of Malignancy and Differential Diagnosis of Urothelial Neoplasms. 61
32774371 2020
5
A Case of Papillary Urothelial Neoplasm of Low Malignant Potential (PUNLMP) in Childhood. 61
33274107 2020
6
The Association of A Number of Predictive Factors for The Recurrence of Papillary Urothelial Neoplasm of Low Malignant Potential: Prognostic Analysis From Multiple Academic Centers. 61
30882164 2019
7
Diagnostic difficulties in cases of papillary urothelial neoplasm of low malignant potential, urothelial proliferation of uncertain malignant potential, urothelial dysplasia and urothelial papilloma: A review of current literature. 61
29395466 2019
8
Grading of Urothelial Carcinoma and The New "World Health Organisation Classification of Tumours of the Urinary System and Male Genital Organs 2016". 61
29366854 2019
9
Relapsed papillary urothelial neoplasm of low malignant potential (PUNLMP) of the young age: a case report and a review of the literature. 61
31072376 2019
10
Chaperone-assisted selective autophagy in healthy and papillomavirus-associated neoplastic urothelium of cattle. 61
29981700 2018
11
Immunohistochemical expression profiles of MUC1 and MUC2 mucins in urothelial tumors of bladder. 61
30004053 2018
12
Biological significance of TERT promoter mutation in papillary urothelial neoplasm of low malignant potential. 61
29193225 2018
13
Study of Proliferating cell nuclear antigen expression and Angiogenesis in Urothelial neoplasms: Correlation with tumor grade and stage. 61
29719336 2018
14
Reduction of Tat-interacting Protein 30 Expression Could be a Prognostic Marker in Bladder Urothelial Cancer. 61
29336367 2018
15
Evaluation of MUC1 and P53 expressions in noninvasive papillary urothelial neoplasms of bladder, their relationship with tumor grade and role in the differential diagnosis. 61
29323063 2017
16
Pearls and Pitfalls in Diagnosing Pediatric Urinary Bladder Masses. 61
29019749 2017
17
TERT Promoter Mutations Occur Frequently in Urothelial Papilloma and Papillary Urothelial Neoplasm of Low Malignant Potential. 61
28040359 2017
18
Papillary Urothelial Neoplasm of Low Malignant Potential (PUNLMP) After Initial TUR-BT: Comparative Analyses with Noninvasive Low-Grade Papillary Urothelial Carcinoma (LGPUC). 61
28928878 2017
19
Polypoid urothelial tumor with inverted growth pattern in the renal pelvis: morphologic and molecular characteristics of a unique diagnostic entity. 61
27574810 2017
20
Nonmuscular Invasive Urothelial Carcinoma of the Bladder in Pediatric and Young Adult Patients: Age-related Outcomes. 61
27450943 2017
21
Elevated preoperative plasma fibrinogen level is an independent predictor of malignancy and advanced stage disease in patients with bladder urothelial tumors. 61
27826047 2016
22
Transitional Cell Carcinoma in the Pediatric Patient: A Review of the Literature. 61
26802795 2016
23
H-RAS mutation is a key molecular feature of pediatric urothelial bladder cancer. A detailed report of three cases. 61
26522772 2016
24
Urothelial neoplasm of the bladder in childhood and adolescence: a rare disease. 61
27256177 2016
25
The pathology of urinary bladder lesions with an inverted growth pattern. 61
27041933 2016
26
Minichromosome maintenance complex component 7 has an important role in the invasion of papillary urothelial neoplasia. 61
26622601 2015
27
How to Name Papillary Tumors of the Bladder in Children: Transitional Cell Carcinoma or Papillary Urothelial Neoplasm of Low Malignant Potential? 61
26169007 2015
28
Urinary bladder xanthoma: a multi-institutional series of 17 cases. 61
25580863 2015
29
Cystoscopic findings: a video tutorial. 61
25619539 2015
30
Molecular and clinical support for a four-tiered grading system for bladder cancer based on the WHO 1973 and 2004 classifications. 61
25431236 2015
31
Transurethral Resection of the Bladder Tumour as a Treatment Method in Children with Transitional Cell Carcinoma of the Bladder--Analysis of Our Material and Literature Review. 61
26467141 2015
32
Urothelial carcinoma of the urinary bladder in pediatric patients: a long-term follow-up. 61
25787072 2015
33
Long-term outcome of primary Papillary Urothelial Neoplasm of Low Malignant Potential (PUNLMP) including PUNLMP with inverted growth. 61
25886613 2015
34
Bladder urothelial neoplasms in pediatric age: experience at three tertiary centers. 61
25305695 2015
35
Lymphotoxin β receptor activation promotes bladder cancer in a nuclear factor-κB-dependent manner. 61
25369740 2015
36
CLINICO-PATHOLOGICAL PATTERN, CLASSIFICATION AND STAGING OF URINARY BLADDER CARCINOMAS--A FIVE YEARS EXPERIENCE AT A TERTIARY CARE HOSPITAL IN CENTRAL PUNJAB. . 61
26182758 2015
37
Bladder papillary urothelial neoplasm of low malignant potential in Chinese: a clinical and pathological analysis. 61
26191263 2015
38
Molecular characteristics of urothelial neoplasms in children and young adults: a subset of tumors from young patients harbors chromosomal abnormalities but not FGFR3 or TP53 gene mutations. 61
24743222 2014
39
Urothelial Tumors of the Urinary Bladder in Two Adolescent Patients: Emphasis on Follow-up Methods. 61
24955230 2014
40
Recurrent papillary urothelial neoplasm of low malignant potential. Subtle architectural disorder detected by quantitative analysis in DAXX-immunostained tissue sections. 61
24565208 2014
41
Long term outcome of primary urothelial papilloma: a single institution cohort. 61
24300727 2014
42
Bovine papillomavirus type 2 (BPV-2) E5 oncoprotein binds to the subunit D of the V₁-ATPase proton pump in naturally occurring urothelial tumors of the urinary bladder of cattle. 61
24586417 2014
43
Urinary bladder cancer in yemen. 61
24044060 2013
44
[Quality of care in patients with newly diagnosed bladder cancer: a prospective assessment in northern Germany]. 61
23494336 2013
45
Gene expression study related with the intrinsic pathway of apoptosis in bladder cancer by real-time PCR technique. 61
23613234 2013
46
[Urothelial carcinoma in patients under 40 years. Review of the cancer committee of the French Association of Urology]. 61
23446281 2013
47
Expression of pigment epithelium-derived factor and tumor necrosis factor-α is correlated in bladder tumor and is related to tumor angiogenesis. 61
21292512 2013
48
Urothelial eddies in papillary urothelial neoplasms: a distinct morphologic pattern with low risk for progression. 61
23923064 2013
49
Bovine papillomavirus type 2 infection and microscopic patterns of urothelial tumors of the urinary bladder in water buffaloes. 61
23762866 2013
50
Mismatch repair hMSH2, hMLH1, hMSH6 and hPMS2 mRNA expression profiles in precancerous and cancerous urothelium. 61
23255936 2013

Variations for Non-Invasive Bladder Papillary Urothelial Neoplasm

Expression for Non-Invasive Bladder Papillary Urothelial Neoplasm

Search GEO for disease gene expression data for Non-Invasive Bladder Papillary Urothelial Neoplasm.

Pathways for Non-Invasive Bladder Papillary Urothelial Neoplasm

Pathways related to Non-Invasive Bladder Papillary Urothelial Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.66 UPK3A TP53 FGFR3

GO Terms for Non-Invasive Bladder Papillary Urothelial Neoplasm

Biological processes related to Non-Invasive Bladder Papillary Urothelial Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of mitotic cell cycle GO:0045930 9.32 TP53 BRINP1
2 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 9.26 TP53 BAG6
3 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0042771 9.16 TP53 BAG6
4 apoptotic process GO:0006915 9.02 TP53 KRT20 HTATIP2 FGFR3 BAG6
5 negative regulation of proteolysis GO:0045861 8.96 TP53 BAG6

Molecular functions related to Non-Invasive Bladder Papillary Urothelial Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 disordered domain specific binding GO:0097718 8.62 TP53 NUMA1

Sources for Non-Invasive Bladder Papillary Urothelial Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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