MCID: NNS006
MIFTS: 26

Non-Suppurative Otitis Media

Categories: Ear diseases

Aliases & Classifications for Non-Suppurative Otitis Media

MalaCards integrated aliases for Non-Suppurative Otitis Media:

Name: Non-Suppurative Otitis Media 12 15 73
Nonsuppurative Otitis Media 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11180
ICD10 33 H65 H65.9 H65.90
ICD9CM 35 381.4
UMLS 73 C0271446

Summaries for Non-Suppurative Otitis Media

Disease Ontology : 12 A otitis media which involves transudation of fluid in the middle ear without pus formation.

MalaCards based summary : Non-Suppurative Otitis Media, also known as nonsuppurative otitis media, is related to eustachian tube disease and acute serous otitis media. An important gene associated with Non-Suppurative Otitis Media is GJA8 (Gap Junction Protein Alpha 8), and among its related pathways/superpathways are Allograft rejection and Bacterial infections in CF airways.

Related Diseases for Non-Suppurative Otitis Media

Diseases related to Non-Suppurative Otitis Media via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
# Related Disease Score Top Affiliating Genes
1 eustachian tube disease 32.5 CANX CDK9 PGRMC1
2 acute serous otitis media 11.4
3 serous glue ear 11.4
4 otitis media 10.4
5 suppurative otitis media 10.4
6 patulous eustachian tube 10.3 CANX CDK9 PGRMC1
7 lateral medullary syndrome 10.3 CANX PRTN3
8 cough variant asthma 10.3 IL4 IL5
9 egg allergy 10.3 IL4 IL5
10 inflammatory bowel disease 4 10.3 IL4 IL5
11 scleritis 10.3 IL4 IL5
12 intrinsic asthma 10.2 IL4 IL5
13 atopic keratoconjunctivitis 10.2 IL4 IL5
14 angiostrongyliasis 10.2 IL4 IL5
15 trichinosis 10.2 IL4 IL5
16 apple allergy 10.2 IL4 IL5
17 latex allergy 10.2 IL4 IL5
18 eosinophilic meningitis 10.2 IL4 IL5
19 intestinal schistosomiasis 10.2 IL4 IL5
20 gastrointestinal allergy 10.2 IL4 IL5
21 urinary schistosomiasis 10.2 IL4 IL5
22 chronic conjunctivitis 10.2 IL4 IL5
23 eosinophilic gastritis 10.2 IL4 IL5
24 kimura disease 10.2 IL4 IL5
25 folliculitis 10.2 IL4 IL5
26 vernal keratoconjunctivitis 10.1 IL4 IL5
27 toxic oil syndrome 10.1 IL4 IL5
28 primary amebic meningoencephalitis 10.1 IL4 IL5
29 anterior scleritis 10.1 IL5 PRTN3
30 conjunctival disease 10.1 IL4 IL5
31 allergic bronchopulmonary aspergillosis 10.0 IL4 IL5
32 enterobiasis 10.0 IL4 IL5
33 milk allergy 10.0 IL4 IL5
34 churg-strauss syndrome 10.0 IL5 PRTN3
35 pulmonary eosinophilia 9.9 IL4 IL5
36 paranasal sinus disease 9.9 IL4 IL5
37 chronic tic disorder 9.8 CTSB IL4 IL5
38 onchocerciasis 9.8 IL4 IL5
39 allergic conjunctivitis 9.7 IL4 IL5
40 hypersensitivity reaction disease 9.7 IL4 IL5 PRTN3
41 immune system disease 9.6 IL4 IL5 PRTN3
42 cerebellopontine angle tumor 9.5 CTSS FKBP4
43 nasal cavity disease 9.4 IL4 IL5
44 cercarial dermatitis 8.9 CTSB CTSS IL4 IL5

Graphical network of the top 20 diseases related to Non-Suppurative Otitis Media:



Diseases related to Non-Suppurative Otitis Media

Symptoms & Phenotypes for Non-Suppurative Otitis Media

Drugs & Therapeutics for Non-Suppurative Otitis Media

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Microbiome Variability and Antibiotic Resistance of Chronic Suppurative Otitis Not yet recruiting NCT03456739

Search NIH Clinical Center for Non-Suppurative Otitis Media

Genetic Tests for Non-Suppurative Otitis Media

Anatomical Context for Non-Suppurative Otitis Media

Publications for Non-Suppurative Otitis Media

Articles related to Non-Suppurative Otitis Media:

# Title Authors Year
1
Non-suppurative otitis media. ( 3235847 )
1988
2
Non-suppurative otitis media in children. (A retrospective study of 100 cases). ( 429896 )
1979
3
Analysis of suppurative otitis media in children: aetiology of non-suppurative otitis media. ( 1152752 )
1975
4
Etiologic factors in non-suppurative otitis media. ( 1195971 )
1975
5
Surface tension lowering substance of the Eustachian tube in non-suppurative otitis media: an experiment with dogs. ( 4686674 )
1973

Variations for Non-Suppurative Otitis Media

Expression for Non-Suppurative Otitis Media

Search GEO for disease gene expression data for Non-Suppurative Otitis Media.

Pathways for Non-Suppurative Otitis Media

GO Terms for Non-Suppurative Otitis Media

Cellular components related to Non-Suppurative Otitis Media according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endolysosome lumen GO:0036021 8.62 CTSB CTSS

Biological processes related to Non-Suppurative Otitis Media according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neutrophil degranulation GO:0043312 9.46 CTSB CTSS PGRMC1 PRTN3
2 cellular response to thyroid hormone stimulus GO:0097067 8.96 CTSB CTSS
3 collagen catabolic process GO:0030574 8.8 CTSB CTSS PRTN3

Molecular functions related to Non-Suppurative Otitis Media according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 proteoglycan binding GO:0043394 8.62 CTSB CTSS

Sources for Non-Suppurative Otitis Media

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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