MCID: NNS033
MIFTS: 16

Non-Syndromic Male Infertility Due to Sperm Motility Disorder

Categories: Rare diseases, Reproductive diseases

Aliases & Classifications for Non-Syndromic Male Infertility Due to Sperm Motility Disorder

MalaCards integrated aliases for Non-Syndromic Male Infertility Due to Sperm Motility Disorder:

Name: Non-Syndromic Male Infertility Due to Sperm Motility Disorder 59
Non-Syndromic Male Infertility Due Asthenozoospermia 59

Characteristics:

Orphanet epidemiological data:

59
non-syndromic male infertility due to sperm motility disorder
Inheritance: Autosomal recessive; Age of onset: Adult;

Classifications:

Orphanet: 59  
Rare infertility disorders


External Ids:

Orphanet 59 ORPHA276234
ICD10 via Orphanet 34 N46

Summaries for Non-Syndromic Male Infertility Due to Sperm Motility Disorder

MalaCards based summary : Non-Syndromic Male Infertility Due to Sperm Motility Disorder, also known as non-syndromic male infertility due asthenozoospermia, is related to male infertility and kartagener syndrome. An important gene associated with Non-Syndromic Male Infertility Due to Sperm Motility Disorder is DNAH1 (Dynein Axonemal Heavy Chain 1). Related phenotypes are cellular and reproductive system

Related Diseases for Non-Syndromic Male Infertility Due to Sperm Motility Disorder

Diseases related to Non-Syndromic Male Infertility Due to Sperm Motility Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 male infertility 10.0 CATSPER1 DNAH1
2 kartagener syndrome 9.9 AK7 DNAH1

Symptoms & Phenotypes for Non-Syndromic Male Infertility Due to Sperm Motility Disorder

MGI Mouse Phenotypes related to Non-Syndromic Male Infertility Due to Sperm Motility Disorder:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.5 AK7 CATSPER1 CFAP43 CFAP44 SEPT12 SLC26A8
2 reproductive system MP:0005389 9.23 AK7 CATSPER1 CFAP43 CFAP44 CFAP69 DNAH1

Drugs & Therapeutics for Non-Syndromic Male Infertility Due to Sperm Motility Disorder

Search Clinical Trials , NIH Clinical Center for Non-Syndromic Male Infertility Due to Sperm Motility Disorder

Genetic Tests for Non-Syndromic Male Infertility Due to Sperm Motility Disorder

Anatomical Context for Non-Syndromic Male Infertility Due to Sperm Motility Disorder

Publications for Non-Syndromic Male Infertility Due to Sperm Motility Disorder

Variations for Non-Syndromic Male Infertility Due to Sperm Motility Disorder

Expression for Non-Syndromic Male Infertility Due to Sperm Motility Disorder

Search GEO for disease gene expression data for Non-Syndromic Male Infertility Due to Sperm Motility Disorder.

Pathways for Non-Syndromic Male Infertility Due to Sperm Motility Disorder

GO Terms for Non-Syndromic Male Infertility Due to Sperm Motility Disorder

Cellular components related to Non-Syndromic Male Infertility Due to Sperm Motility Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoskeleton GO:0005856 9.62 DNAH1 SEPT12 SPAG17 WDR66
2 cilium GO:0005929 9.56 CATSPER1 DNAH1 SEPT12 SPAG17
3 cell projection GO:0042995 9.5 CATSPER1 CFAP43 CFAP44 DNAH1 SEPT12 SPAG17
4 axoneme GO:0005930 9.33 CFAP43 DNAH1 WDR66
5 motile cilium GO:0031514 9.17 CATSPER1 CFAP43 CFAP44 DNAH1 SEPT12 SPAG17

Biological processes related to Non-Syndromic Male Infertility Due to Sperm Motility Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 spermatogenesis GO:0007283 9.58 CATSPER1 SEPT12 SLC26A8
2 cilium movement GO:0003341 9.37 DNAH1 WDR66
3 cilium-dependent cell motility GO:0060285 9.32 CFAP44 DNAH1
4 epithelial cilium movement GO:0003351 9.26 DNAH1 SPAG17
5 sperm motility GO:0097722 9.16 CFAP43 CFAP44
6 sperm axoneme assembly GO:0007288 9.13 CFAP43 CFAP44 DNAH1
7 flagellated sperm motility GO:0030317 8.92 CATSPER1 DNAH1 SEPT12 SLC26A8

Sources for Non-Syndromic Male Infertility Due to Sperm Motility Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
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42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
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58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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