MCID: NNM008
MIFTS: 20

Nonmucinous Bronchioloalveolar Adenocarcinoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Nonmucinous Bronchioloalveolar Adenocarcinoma

MalaCards integrated aliases for Nonmucinous Bronchioloalveolar Adenocarcinoma:

Name: Nonmucinous Bronchioloalveolar Adenocarcinoma 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0080186

Summaries for Nonmucinous Bronchioloalveolar Adenocarcinoma

Disease Ontology : 12 A bronchiolo-alveolar adenocarcinoma that is characterized by cells with cuboidal or columnar morphology with eosinophilic or clear cytoplasm and shows Clara cell or type 2 pneumocyte differentiation.

MalaCards based summary : Nonmucinous Bronchioloalveolar Adenocarcinoma is related to mixed mucinous and nonmucinous bronchioloalveolar adenocarcinoma and colon adenocarcinoma. An important gene associated with Nonmucinous Bronchioloalveolar Adenocarcinoma is SLC27A5 (Solute Carrier Family 27 Member 5), and among its related pathways/superpathways are Relaxin signaling pathway and TGF-beta Signaling Pathways. Affiliated tissues include breast, lung and thyroid.

Related Diseases for Nonmucinous Bronchioloalveolar Adenocarcinoma

Diseases related to Nonmucinous Bronchioloalveolar Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 75)
# Related Disease Score Top Affiliating Genes
1 mixed mucinous and nonmucinous bronchioloalveolar adenocarcinoma 12.6
2 colon adenocarcinoma 10.3
3 adenocarcinoma 10.3
4 atrophic vulva 10.1 KRT20 ESR1
5 breast osteosarcoma 10.0 KRT20 ESR1
6 breast neuroendocrine neoplasm 10.0 KRT20 ESR1
7 in situ pulmonary adenocarcinoma 10.0 SLC27A5 NKX2-1
8 sweat gland cancer 10.0 KRT20 ESR1
9 endocervical adenocarcinoma 10.0 KRT20 ESR1
10 cervical adenocarcinoma 10.0 KRT20 ESR1
11 tubular adenocarcinoma 10.0 KRT20 ESR1
12 mammary paget's disease 10.0 KRT20 ESR1
13 clear cell adenocarcinoma 10.0 KRT20 ESR1
14 neuroendocrine carcinoma 10.0 NKX2-1 KRT20
15 small cell carcinoma 10.0 NKX2-1 KRT20
16 small cell carcinoma of the bladder 10.0 NKX2-1 KRT20
17 thymus clear cell carcinoma 10.0 NKX2-1 KRT20
18 thyroid angiosarcoma 10.0 NKX2-1 KRT20
19 lung acinar adenocarcinoma 10.0 NKX2-1 KRT20
20 horseshoe kidney 10.0 NKX2-1 KRT20
21 benign teratoma 10.0 NKX2-1 KRT20
22 papillary serous adenocarcinoma 10.0 NKX2-1 KRT20
23 ovary adenocarcinoma 9.9 KRT20 ESR1
24 cystic teratoma 9.9 NKX2-1 KRT20
25 thymic carcinoma 9.9 NKX2-1 KRT20
26 cavernous hemangioma 9.9 NKX2-1 KRT20
27 lung benign neoplasm 9.9 NKX2-1 KRT20
28 merkel cell carcinoma 9.9 NKX2-1 KRT20
29 large cell carcinoma 9.8 NKX2-1 KRT20
30 oncocytoma 9.8 NKX2-1 KRT20
31 alzheimer disease mitochondrial 9.8 ESR2 ESR1
32 progesterone resistance 9.8 ESR2 ESR1
33 gender identity disorder 9.8 ESR2 ESR1
34 estrogen excess 9.8 ESR2 ESR1
35 progesterone-receptor positive breast cancer 9.8 ESR2 ESR1
36 dental fluorosis 9.8 ESR2 ESR1
37 endometriosis of ovary 9.8 ESR2 ESR1
38 lobular neoplasia 9.8 ESR2 ESR1
39 vaginitis 9.8 ESR2 ESR1
40 testicular germ cell cancer 9.8 ESR2 ESR1
41 germ cell cancer 9.8 ESR2 ESR1
42 small cell cancer of the lung 9.8 NKX2-1 KRT20
43 uterine benign neoplasm 9.8 ESR2 ESR1
44 reproductive organ benign neoplasm 9.8 ESR2 ESR1
45 adenomyosis 9.8 ESR2 ESR1
46 pelvic organ prolapse 9.8 ESR2 ESR1
47 amelogenesis imperfecta, type ig 9.8 ESR2 ESR1
48 teeth hard tissue disease 9.8 ESR2 ESR1
49 colorectal adenocarcinoma 9.8 NKX2-1 KRT20
50 primary pigmented nodular adrenocortical disease 9.8 ESR2 ESR1

Graphical network of the top 20 diseases related to Nonmucinous Bronchioloalveolar Adenocarcinoma:



Diseases related to Nonmucinous Bronchioloalveolar Adenocarcinoma

Symptoms & Phenotypes for Nonmucinous Bronchioloalveolar Adenocarcinoma

Drugs & Therapeutics for Nonmucinous Bronchioloalveolar Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Nonmucinous Bronchioloalveolar Adenocarcinoma

Genetic Tests for Nonmucinous Bronchioloalveolar Adenocarcinoma

Anatomical Context for Nonmucinous Bronchioloalveolar Adenocarcinoma

MalaCards organs/tissues related to Nonmucinous Bronchioloalveolar Adenocarcinoma:

40
Breast, Lung, Thyroid, Ovary, Thymus, Colon, Kidney

Publications for Nonmucinous Bronchioloalveolar Adenocarcinoma

Variations for Nonmucinous Bronchioloalveolar Adenocarcinoma

Expression for Nonmucinous Bronchioloalveolar Adenocarcinoma

Search GEO for disease gene expression data for Nonmucinous Bronchioloalveolar Adenocarcinoma.

Pathways for Nonmucinous Bronchioloalveolar Adenocarcinoma

GO Terms for Nonmucinous Bronchioloalveolar Adenocarcinoma

Biological processes related to Nonmucinous Bronchioloalveolar Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of DNA-binding transcription factor activity GO:0051091 9.16 ESR2 ESR1
2 positive regulation of transcription, DNA-templated GO:0045893 9.13 NKX2-1 ESR2 ESR1
3 intracellular estrogen receptor signaling pathway GO:0030520 8.62 ESR2 ESR1

Molecular functions related to Nonmucinous Bronchioloalveolar Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sequence-specific DNA binding GO:0043565 9.61 NKX2-1 ESR2 ESR1
2 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.58 NKX2-1 ESR2 ESR1
3 enzyme binding GO:0019899 9.43 NKX2-1 ESR2 ESR1
4 steroid hormone receptor activity GO:0003707 9.37 ESR2 ESR1
5 nuclear receptor activity GO:0004879 9.32 ESR2 ESR1
6 steroid binding GO:0005496 9.16 ESR2 ESR1
7 estrogen receptor activity GO:0030284 8.96 ESR2 ESR1
8 estrogen response element binding GO:0034056 8.62 ESR2 ESR1

Sources for Nonmucinous Bronchioloalveolar Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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