MCID: NNM008
MIFTS: 18

Nonmucinous Bronchioloalveolar Adenocarcinoma

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Nonmucinous Bronchioloalveolar Adenocarcinoma

MalaCards integrated aliases for Nonmucinous Bronchioloalveolar Adenocarcinoma:

Name: Nonmucinous Bronchioloalveolar Adenocarcinoma 12 15

Classifications:



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Disease Ontology 12 DOID:0080186

Summaries for Nonmucinous Bronchioloalveolar Adenocarcinoma

Disease Ontology : 12 A bronchiolo-alveolar adenocarcinoma that is characterized by cells with cuboidal or columnar morphology with eosinophilic or clear cytoplasm and shows Clara cell or type 2 pneumocyte differentiation.

MalaCards based summary : Nonmucinous Bronchioloalveolar Adenocarcinoma is related to colon adenocarcinoma and mixed mucinous and nonmucinous bronchioloalveolar adenocarcinoma. An important gene associated with Nonmucinous Bronchioloalveolar Adenocarcinoma is SLC27A5 (Solute Carrier Family 27 Member 5), and among its related pathways/superpathways are Circadian entrainment and TGF-beta Signaling Pathways.

Related Diseases for Nonmucinous Bronchioloalveolar Adenocarcinoma

Diseases related to Nonmucinous Bronchioloalveolar Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
# Related Disease Score Top Affiliating Genes
1 colon adenocarcinoma 29.7 KRT20 ESR2
2 mixed mucinous and nonmucinous bronchioloalveolar adenocarcinoma 12.6
3 adenocarcinoma 10.3
4 glycogen-rich clear cell breast carcinoma 10.1 KRT20 ESR1
5 mammary paget's disease 10.1 KRT20 ESR1
6 small cell carcinoma 10.1 NKX2-1 KRT20
7 tubular adenocarcinoma 10.1 KRT20 ESR1
8 small cell carcinoma of the bladder 10.1 NKX2-1 KRT20
9 colloid adenoma 10.1 NKX2-1 KRT20
10 lung acinar adenocarcinoma 10.1 NKX2-1 KRT20
11 papillary serous adenocarcinoma 10.0 NKX2-1 KRT20
12 rete testis adenocarcinoma 10.0 NKX2-1 KRT20
13 cervical adenocarcinoma 10.0 KRT20 ESR1
14 sweat gland cancer 10.0 KRT20 ESR1
15 mucinous bronchioloalveolar adenocarcinoma 10.0 NKX2-1 KRT20
16 rete testis neoplasm 10.0 NKX2-1 KRT20
17 ovarian cystic teratoma 10.0 NKX2-1 KRT20
18 cystic teratoma 10.0 NKX2-1 KRT20
19 horseshoe kidney 10.0 NKX2-1 KRT20
20 hidradenocarcinoma 10.0 NKX2-1 ESR1
21 large cell neuroendocrine carcinoma 10.0 NKX2-1 KRT20
22 mucinous adenocarcinoma 10.0 NKX2-1 KRT20
23 bronchiolo-alveolar adenocarcinoma 10.0 NKX2-1 KRT20
24 merkel cell carcinoma 9.9 NKX2-1 KRT20
25 papillary carcinoma 9.9 NKX2-1 KRT20
26 postmenopausal atrophic vaginitis 9.9 ESR2 ESR1
27 vaginitis 9.9 ESR2 ESR1
28 progesterone-receptor positive breast cancer 9.9 ESR2 ESR1
29 progesterone resistance 9.9 ESR2 ESR1
30 gender identity disorder 9.9 ESR2 ESR1
31 estrogen excess 9.9 ESR2 ESR1
32 dental fluorosis 9.8 ESR2 ESR1
33 lobular neoplasia 9.8 ESR2 ESR1
34 endometriosis of ovary 9.8 ESR2 ESR1
35 endometriosis 9.8 ESR2 ESR1
36 mesothelioma, malignant 9.8 NKX2-1 KRT20
37 sporadic breast cancer 9.7 ESR2 ESR1
38 female reproductive system disease 9.7 ESR2 ESR1
39 neuroendocrine tumor 9.7 NKX2-1 KRT20
40 reproductive system disease 9.7 ESR2 ESR1
41 germ cell cancer 9.7 ESR2 ESR1
42 small cell cancer of the lung 9.7 NKX2-1 KRT20
43 endometrial adenocarcinoma 9.7 ESR2 ESR1
44 leiomyoma 9.6 ESR2 ESR1
45 thyroid carcinoma, familial medullary 9.5 NKX2-1 ESR2
46 ovarian disease 9.4 ESR2 ESR1
47 lung cancer susceptibility 3 9.2 NKX2-1 KRT20 ESR2
48 breast disease 9.2 ESR2 ESR1

Graphical network of the top 20 diseases related to Nonmucinous Bronchioloalveolar Adenocarcinoma:



Diseases related to Nonmucinous Bronchioloalveolar Adenocarcinoma

Symptoms & Phenotypes for Nonmucinous Bronchioloalveolar Adenocarcinoma

Drugs & Therapeutics for Nonmucinous Bronchioloalveolar Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Nonmucinous Bronchioloalveolar Adenocarcinoma

Genetic Tests for Nonmucinous Bronchioloalveolar Adenocarcinoma

Anatomical Context for Nonmucinous Bronchioloalveolar Adenocarcinoma

Publications for Nonmucinous Bronchioloalveolar Adenocarcinoma

Variations for Nonmucinous Bronchioloalveolar Adenocarcinoma

Expression for Nonmucinous Bronchioloalveolar Adenocarcinoma

Search GEO for disease gene expression data for Nonmucinous Bronchioloalveolar Adenocarcinoma.

Pathways for Nonmucinous Bronchioloalveolar Adenocarcinoma

GO Terms for Nonmucinous Bronchioloalveolar Adenocarcinoma

Biological processes related to Nonmucinous Bronchioloalveolar Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of transcription by RNA polymerase II GO:0000122 9.43 NKX2-1 ESR2 ESR1
2 positive regulation of DNA-binding transcription factor activity GO:0051091 9.16 ESR2 ESR1
3 positive regulation of transcription, DNA-templated GO:0045893 9.13 NKX2-1 ESR2 ESR1
4 intracellular estrogen receptor signaling pathway GO:0030520 8.62 ESR2 ESR1

Molecular functions related to Nonmucinous Bronchioloalveolar Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sequence-specific DNA binding GO:0043565 9.61 NKX2-1 ESR2 ESR1
2 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.58 NKX2-1 ESR2 ESR1
3 enzyme binding GO:0019899 9.43 NKX2-1 ESR2 ESR1
4 steroid hormone receptor activity GO:0003707 9.37 ESR2 ESR1
5 nuclear receptor activity GO:0004879 9.32 ESR2 ESR1
6 steroid binding GO:0005496 9.16 ESR2 ESR1
7 estrogen receptor activity GO:0030284 8.96 ESR2 ESR1
8 estrogen response element binding GO:0034056 8.62 ESR2 ESR1

Sources for Nonmucinous Bronchioloalveolar Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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