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MCID: NNS011
MIFTS: 34

Nonseminomatous Germ Cell Tumor

Categories: Rare diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Nonseminomatous Germ Cell Tumor

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MalaCards integrated aliases for Nonseminomatous Germ Cell Tumor:

Name: Nonseminomatous Germ Cell Tumor 54 74
Non-Seminomatous Germ-Cell Tumors 54
Nsgct 54

Classifications:

MalaCards categories:
Global: Rare diseases
See all MalaCards categories (disease lists)


External Ids:

UMLS 74 C1266158
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Summaries for Nonseminomatous Germ Cell Tumor

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NIH Rare Diseases : 54 Nonseminomatous germ celltumors are cancerous tumors commonly found in the pineal gland in the brain, in the mediastinum, or in the abdomen. They originate from cells that were meant to form sex cells (i.e., sperm or eggs). They are often large and have a tendency to spread more quickly than the other type of germ cell tumorĀ (i.e., seminoma type). Possible early signs of this cancer include chest pain and breathing problems.

MalaCards based summary : Nonseminomatous Germ Cell Tumor, also known as non-seminomatous germ-cell tumors, is related to testicular cancer and choriocarcinoma. An important gene associated with Nonseminomatous Germ Cell Tumor is AFP (Alpha Fetoprotein), and among its related pathways/superpathways is Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors. The drugs Ifosfamide and Mechlorethamine have been mentioned in the context of this disorder. Affiliated tissues include testis, brain and pineal, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

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Related Diseases for Nonseminomatous Germ Cell Tumor

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Diseases related to Nonseminomatous Germ Cell Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 54)
# Related Disease Score Top Affiliating Genes
1 testicular cancer 30.2 AFP CGB5
2 choriocarcinoma 30.0 CGB5 CGB7
3 extragonadal nonseminomatous germ cell tumor 12.6
4 testicular germ cell tumor 11.6
5 testicular seminoma 11.6
6 germ cells tumors 11.1
7 teratoma 10.8
8 growing teratoma syndrome 10.5
9 mature teratoma 10.4
10 ewing's family of tumors 10.3
11 thrombophilia due to thrombin defect 10.2
12 androgen insensitivity, partial 10.2
13 acute promyelocytic leukemia 10.2
14 angiosarcoma 10.2
15 thrombosis 10.2
16 pericarditis 10.2
17 adenocarcinoma 10.2
18 rhabdomyosarcoma 10.2
19 hyperthyroidism 10.2
20 acute respiratory distress syndrome 10.2
21 encephalopathy 10.2
22 renal cell carcinoma, nonpapillary 10.1
23 prostate cancer 10.1
24 hemolytic anemia 10.1
25 leukemia 10.1
26 thrombocytopenia 10.1
27 hydronephrosis 10.1
28 hemopericardium 10.1
29 infant gynecomastia 10.1
30 pericardial effusion 10.1
31 gynecomastia 10.1
32 endodermal sinus tumor 10.1
33 germ cell cancer 10.1
34 embryonal carcinoma 10.1
35 placental site trophoblastic tumor 10.1
36 malignant teratoma 10.1
37 seizure disorder 10.1
38 sacrococcygeal teratoma 10.0 AFP CGB7
39 triploidy 10.0 AFP CGB7
40 mixed cell type cancer 9.9 AFP ERBB2
41 tubular adenocarcinoma 9.9 AFP ERBB2
42 uterine anomalies 9.9 AFP ERBB2
43 gonadal disease 9.9 AFP ERBB2
44 gastrointestinal system cancer 9.9 AFP ERBB2
45 malignant sertoli cell tumor 9.9 AFP CGB5
46 corpus luteum cyst 9.8 AFP CGB5
47 extragonadal germ cell cancer 9.8 AFP CGB5
48 endocrine gland cancer 9.8 AFP ERBB2
49 ectopic pregnancy 9.8 CGB5 CGB7
50 gastrointestinal system disease 9.8 AFP ERBB2

Graphical network of the top 20 diseases related to Nonseminomatous Germ Cell Tumor:



Diseases related to Nonseminomatous Germ Cell Tumor
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Symptoms & Phenotypes for Nonseminomatous Germ Cell Tumor

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GenomeRNAi Phenotypes related to Nonseminomatous Germ Cell Tumor according to GeneCards Suite gene sharing:

27 (show all 14)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-134 10.26 CGB5 CGB7
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-160 10.26 CGB5 CGB7
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-179 10.26 CGB5 CGB7
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-59 10.26 CGB5 CGB7
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-95 10.26 CGB5 CGB7
6 Increased shRNA abundance (Z-score > 2) GR00366-A-118 9.6 CGB5 CGB7
7 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.6 ERBB2
8 Increased shRNA abundance (Z-score > 2) GR00366-A-163 9.6 ERBB2
9 Increased shRNA abundance (Z-score > 2) GR00366-A-168 9.6 ERBB2
10 Increased shRNA abundance (Z-score > 2) GR00366-A-207 9.6 ERBB2
11 Increased shRNA abundance (Z-score > 2) GR00366-A-32 9.6 CGB5 CGB7 ERBB2
12 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.6 CGB5 CGB7
13 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.6 ERBB2
14 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.6 ERBB2
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Drugs & Therapeutics for Nonseminomatous Germ Cell Tumor

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Drugs for Nonseminomatous Germ Cell Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 114)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ifosfamide Approved Phase 3,Phase 2,Phase 1 3778-73-2 3690
2
Mechlorethamine Approved, Investigational Phase 3,Phase 2,Phase 1 51-75-2 4033
3
Bleomycin Approved, Investigational Phase 3,Phase 2 11056-06-7 5360373
4
Etoposide Approved Phase 3,Phase 2 33419-42-0 36462
5
Paclitaxel Approved, Vet_approved Phase 3,Phase 2,Phase 1 33069-62-4 36314
6
Oxaliplatin Approved, Investigational Phase 3,Phase 2 61825-94-3 43805 6857599 5310940 9887054
7
Cisplatin Approved Phase 3,Phase 2,Phase 1 15663-27-1 2767 441203 84093
8
Lenograstim Approved, Investigational Phase 2, Phase 3,Phase 3,Phase 1 135968-09-1
9
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 38904 498142
10
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 1177-87-3
11
Mesna Approved, Investigational Phase 3,Phase 1,Phase 2 3375-50-6 598
12
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 50-02-2 5743
13
Promethazine Approved, Investigational Phase 3 60-87-7 4927
14
Diphenhydramine Approved, Investigational Phase 3 147-24-0, 58-73-1 3100
15
Histamine Approved, Investigational Phase 3 51-45-6 774
16
Cyproheptadine Approved Phase 3 129-03-3 2913
17
Vinblastine Approved Phase 3 865-21-4 241903 13342
18 Antimitotic Agents Phase 3,Phase 2,Phase 1
19 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
20
Isophosphamide mustard Phase 3,Phase 2,Phase 1 0
21 Alkylating Agents Phase 3,Phase 2,Phase 1
22 Anti-Bacterial Agents Phase 3,Phase 2
23 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1
24 Antineoplastic Agents, Alkylating Phase 3,Phase 2,Phase 1
25 Etoposide phosphate Phase 3,Phase 2
26 Albumin-Bound Paclitaxel Phase 3,Phase 2,Phase 1
27 Antibiotics, Antitubercular Phase 3,Phase 2
28 Immunologic Factors Phase 3,Phase 2,Phase 1
29 BB 1101 Phase 3,Phase 2,Phase 1
30 Adjuvants, Immunologic Phase 3,Phase 1,Phase 2
31 Gastrointestinal Agents Phase 3,Phase 2
32 Histamine H2 Antagonists Phase 3
33 Dermatologic Agents Phase 3,Phase 2
34 Histamine Antagonists Phase 3
35 Neurotransmitter Agents Phase 3
36 Serotonin Agents Phase 3
37 Serotonin Antagonists Phase 3
38 Anti-Allergic Agents Phase 3
39 Antipruritics Phase 3
40 Histamine H1 Antagonists Phase 3
41
Histamine Phosphate Phase 3 51-74-1 65513
42
Serotonin Investigational, Nutraceutical Phase 3 50-67-9 5202
43
Gemcitabine Approved Phase 2,Phase 1 95058-81-4 60750
44
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 1, Phase 2 7487-88-9 24083
45
Mannitol Approved, Investigational Phase 1, Phase 2 69-65-8 6251 453
46
Ranitidine Approved Phase 1, Phase 2 66357-59-3, 66357-35-5 3001055
47
Furosemide Approved, Vet_approved Phase 1, Phase 2 54-31-9 3440
48
leucovorin Approved Phase 2 58-05-9 143 6006
49
Fluorouracil Approved Phase 2 51-21-8 3385
50
Levoleucovorin Approved, Investigational Phase 2 68538-85-2

Interventional clinical trials:

(show all 38)
# Name Status NCT ID Phase Drugs
1 Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors Unknown status NCT00104676 Phase 3 cisplatin;etoposide;ifosfamide;oxaliplatin;paclitaxel
2 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3 cisplatin;etoposide;paclitaxel
3 Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors Recruiting NCT02375204 Phase 3 paclitaxel;ifosfamide;cisplatin;pegylated G-CSF;G-CSF;carboplatin;etoposide phosphate
4 Trial of 1 Cycle of Adjuvant BEP Chemotherapy in High Risk, Stage 1 Non-seminomatous Germ Cell Testis Tumours Active, not recruiting NCT01726374 Phase 3 BEP(500)
5 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3 cyproheptadine hydrochloride
6 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3 cisplatin;ifosfamide;paclitaxel;vinblastine
7 Trial of Gemcitabine, Cisplatin, and Ifosfamide in Patients With Relapsed Non-Seminomatous Germ-Cell Tumors Unknown status NCT00127049 Phase 2 gemcitabine, ifosfamide, cisplatin, G-CSF
8 High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Metastatic Germ Cell Tumors That Have Not Responded to First-Line Therapy Unknown status NCT01172912 Phase 2 carboplatin;cisplatin;dexamethasone;etoposide;ifosfamide
9 Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors Unknown status NCT00551122 Phase 1, Phase 2 cisplatin;gemcitabine hydrochloride;ifosfamide;paclitaxel
10 High-dose Chemotherapy With Autologous Stem Cell Rescue in Pediatric High-risk Brain Tumors Completed NCT00798811 Phase 2
11 Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell Tumors Completed NCT00957905 Phase 2 Alvocidib Hydrochloride;Fluorouracil;Leucovorin Calcium;Oxaliplatin
12 Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors Completed NCT00301782 Phase 2 carboplatin;cisplatin;etoposide phosphate;vincristine sulfate
13 Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors Completed NCT00470366 Phase 2 cisplatin;ifosfamide;paclitaxel
14 Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to Cisplatin Completed NCT00423852 Phase 1, Phase 2 carboplatin;ifosfamide;paclitaxel
15 Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00453310 Phase 2 sunitinib malate
16 Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors Completed NCT00453232 Phase 2 cisplatin;etoposide
17 Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors Completed NCT00070096 Phase 2 ixabepilone
18 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer Completed NCT00002931 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel
19 A Prospective Study of Cabazitaxel in Patients With Non Seminomatous Germ-cell Tumors Recruiting NCT02115165 Phase 2 Cabazitaxel
20 Reduced Dose Radiotherapy Following High Dose Chemotherapy in Intracranial Non-germinomatous Germ Cell Tumor Recruiting NCT02784054 Phase 2 Carboplatin;Etoposide;Cyclophosphamide;Bleomycin;Thiotepa;Melphalan
21 First Line TIP in Poor Prognosis TGCTs. Recruiting NCT02414685 Phase 2 Paclitaxel;Ifosfamide;Cisplatin
22 Contribution of the Imaging to the Expression of intégrines Ī±vĪ²3 for the Characterization of Residual Masses of Non-seminoma Tumors at the End of Chemotherapy Recruiting NCT02317393 Phase 2
23 PHASE II TRIAL OF THE CYCLIN-DEPEDENT KINASE INHIBITOR PD 0332991 IN PATIENTS WITH CANCER Recruiting NCT01037790 Phase 2 PD-0332991
24 Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors Recruiting NCT00432094 Phase 2 carboplatin;etoposide;ifosfamide;paclitaxel;thiotepa;Mesna
25 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
26 Brentuximab Vedotin in Relapsed/Refractory Germ Cell Tumors Active, not recruiting NCT02689219 Phase 2 Brentuximab Vedotin
27 Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors Active, not recruiting NCT01602666 Phase 2 Carboplatin;Etoposide;Ifosfamide
28 Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers Active, not recruiting NCT02034110 Phase 2 Dabrafenib;Trametinib
29 Evaluating Immune Therapy, Duravalumab (MEDI4736) With Tremelimumab for Relapsed/Refractory Germ Cell Tumors Active, not recruiting NCT03158064 Phase 2 Durvalumab;Tremelimumab
30 Pembrolizumab in Subjects With Incurable Platinum-Refractory Germ Cell Tumors Terminated NCT02499952 Phase 2 Pembrolizumab
31 Palifosfamide in Treating Patients With Recurrent Germ Cell Tumors Terminated NCT01808534 Phase 2 palifosfamide
32 Lapatinib and Paclitaxel in Treating Patients With Advanced Solid Tumors Completed NCT00313599 Phase 1 lapatinib;paclitaxel
33 Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor Active, not recruiting NCT00638898 Phase 1 busulfan;melphalan;topotecan hydrochloride
34 Follow-up Evaluation Using CT Scans in Patients Who Have Been Treated For Metastatic Testicular Cancer Unknown status NCT00553371
35 Diagnostic Study of Patients With Stage I Testicular Cancer Completed NCT00003800 Not Applicable
36 Positron Emission Tomography in Detecting Testicle Cancer Completed NCT00045045 Not Applicable
37 Swiss Austrian German Testicular Cancer Cohort Study - SAG TCCS Recruiting NCT02229916
38 Proton Beam Radiation Therapy for Central Nervous System (CNS) Germ Cell Tumors Active, not recruiting NCT01049230 Not Applicable

Search NIH Clinical Center for Nonseminomatous Germ Cell Tumor

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Genetic Tests for Nonseminomatous Germ Cell Tumor

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Anatomical Context for Nonseminomatous Germ Cell Tumor

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MalaCards organs/tissues related to Nonseminomatous Germ Cell Tumor:

42
Testis, Brain, Pineal, Lymph Node, Bone, Prostate, Testes
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Publications for Nonseminomatous Germ Cell Tumor

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Articles related to Nonseminomatous Germ Cell Tumor:

(show top 50) (show all 170)
# Title Authors Year
1
Huge right ventricular mass revealing a testicular nonseminomatous germ cell tumor. ( 30337794 )
2019
2
Stereotactic Ablative Radiotherapy (SAbR) in the Setting of Metastatic Nonseminomatous Germ Cell Tumor of Testis. ( 31109801 )
2019
3
Dose-reduced first cycle of chemotherapy for prevention of life-threatening acute complications in nonseminomatous germ cell tumor patients with ultra high tumor markers and/or poor performance status. ( 29974210 )
2018
4
Huge right ventricular mass revealing a testicular nonseminomatous germ cell tumor. ( 29983504 )
2018
5
Late Relapse of Nonseminomatous Germ Cell Tumor 24 Years Later. ( 30170087 )
2018
6
Nodule Size After Chemotherapy and Primary-Tumor Teratoma Components Predict Malignancy of Residual Pulmonary Nodules in Metastatic Nonseminomatous Germ Cell Tumor. ( 30191415 )
2018
7
Staged surgical treatment of a primary duodenocaval fistula in a patient with metastatic nonseminomatous germ cell tumor. ( 30528961 )
2018
8
Pericardial effusion as an atypical initial presentation of extra-gonadal nonseminomatous germ cell tumor: a case report and literature review. ( 29492268 )
2018
9
Histologic and Oncologic Outcomes Following Liver Mass Resection With Retroperitoneal Lymph Node Dissection in Patients With Nonseminomatous Germ Cell Tumor. ( 29704586 )
2018
10
The Use of Modified Templates in Early and Advanced Stage Nonseminomatous Germ Cell Tumor. ( 29849605 )
2018
11
Outcomes of active surveillance of clinical stage I non-seminomatous germ cell tumors: sub-analysis of the multi-institutional nationwide case series of the Japanese Urological Association. ( 29672733 )
2018
12
Testicular non-seminomatous germ cell tumors (NSGCT) and brain metastases: About a rare location of the posterior fossa. ( 30211008 )
2018
13
Durable Response to Immune Checkpoint Blockade in a Platinum-Refractory Patient With Nonseminomatous Germ Cell Tumor. ( 28465048 )
2017
14
Evolving patterns of care in the management of stage I non-seminomatous germ cell tumors: data from the California Cancer Registry. ( 27306686 )
2017
15
High-Dose Chemotherapy in a Late Relapse, Platinum-Refractory Nonseminomatous Germ Cell Tumor. ( 27055370 )
2016
16
Laparoscopic Postchemotherapy Retroperitoneal Lymph-Node Dissection Can Be a Standard Option in Defined Nonseminomatous Germ Cell Tumor Patients. ( 27533924 )
2016
17
Perioperative Morbidity and Mortality Associated With Bleomycin in Primary Mediastinal Nonseminomatous Germ Cell Tumor. ( 27621392 )
2016
18
Intratumoral heterogeneity and chemoresistance in nonseminomatous germ cell tumor of the testis. ( 27861143 )
2016
19
Growing Teratoma Syndrome After Treatment of a Nonseminomatous Germ Cell Tumor: A Case Report and a Review of Literature. ( 26952048 )
2014
20
Primary nonseminomatous germ cell tumor in the posterior mediastinum. ( 25473562 )
2014
21
Fatty acid synthase overexpression in adult testicular germ cell tumors: potential role in the progression of non-seminomatous germ cell tumors. ( 24337182 )
2014
22
A prospective study of cognitive function in men with non-seminomatous germ cell tumors. ( 24339329 )
2014
23
Re: tumor marker kinetics predict outcome in patients with relapsed disseminated non-seminomatous germ-cell tumors. ( 24522037 )
2014
24
Postchemotherapy laparoscopic retroperitoneal lymph node dissection for low-volume, stage II, nonseminomatous germ cell tumor: first 100 patients. ( 23021090 )
2013
25
Re: genomic characterization of testis cancer: association of alterations with outcome of clinical stage 1 mixed germ cell nonseminomatous germ cell tumor of the testis. ( 23845335 )
2013
26
Late recurrence of nonseminomatous germ cell tumor successfully treated with intensity-modulated radiation therapy. ( 23868903 )
2013
27
Nonseminomatous germ cell tumor of testis and interrupted treatment. ( 24133836 )
2013
28
Tumor marker kinetics predict outcome in patients with relapsed disseminated non-seminomatous germ-cell tumors. ( 23104726 )
2013
29
Chromosome X-encoded Cancer/Testis antigens are less frequently expressed in non-seminomatous germ cell tumors than in seminomas. ( 23885216 )
2013
30
Controversies in the management of stage 1 non-seminomatous germ cell tumors. ( 23901036 )
2013
31
Laparoscopic retroperitoneal lymph node dissection for clinical stage I nonseminomatous germ cell tumor: a large single institution experience. ( 22177913 )
2012
32
Genomic characterization of testis cancer: association of alterations with outcome of clinical stage 1 mixed germ cell nonseminomatous germ cell tumor of the testis. ( 22503760 )
2012
33
What is the role of enlarged lymph node resection alone in patients with nonseminomatous germ cell tumor who had stage II or III disease? ( 22682983 )
2012
34
Current update of management of clinical stage I non seminomatous germ cell tumors of testis. ( 23730098 )
2012
35
The management of low-stage non-seminomatous germ cell tumors. ( 25992217 )
2012
36
Gynecomastia as a first clinical sign of nonseminomatous germ cell tumor. ( 21625076 )
2011
37
Postchemotherapy residual masses in nonseminomatous germ cell tumor patients: 18F-FLT PET is unlikely to identify mature teratoma, but imaging of alphav beta3 integrin expression could. ( 21536932 )
2011
38
Secondary malignancies among nonseminomatous germ cell tumor cancer survivors. ( 21412759 )
2011
39
Population-based study of treatment guided by tumor marker decline in patients with metastatic nonseminomatous germ cell tumor: a report from the Swedish-Norwegian Testicular Cancer Group. ( 21482994 )
2011
40
Trends of retroperitoneal lymphadenectomy use in patients with nonseminomatous germ cell tumor of the testis: a population-based study. ( 21509630 )
2011
41
Stage I nonseminomatous germ cell tumor of the testis: more questions than answers? ( 21570606 )
2011
42
Resection of primary mediastinal non-seminomatous germ cell tumors: a 28-year experience at memorial sloan-kettering cancer center. ( 21610519 )
2011
43
Prevalence of paraneoplastic hyperthyroidism in patients with metastatic non-seminomatous germ-cell tumors. ( 19605510 )
2010
44
Nonseminomatous germ cell tumor of the testes metastatic to the corpus cavernosum of the penis. ( 19931126 )
2010
45
Clinical relevance of HER-2/neu overexpression in patients with testicular nonseminomatous germ cell tumor. ( 20209452 )
2010
46
Predictive value of modeled AUC(AFP-hCG), a dynamic kinetic parameter characterizing serum tumor marker decline in patients with nonseminomatous germ cell tumor. ( 20472276 )
2010
47
Can a cure be achieved with taxane-based chemotherapy plus surgery in patients with primary mediastinal non-seminomatous germ cell tumors and progression or relapse despite first-line chemotherapy? ( 20215805 )
2010
48
Retroperitoneal extragonadal nonseminomatous germ cell tumor with synchronous orbital metastasis. ( 19197374 )
2009
49
Postchemotherapy laparoscopic retroperitoneal lymph node dissection in nonseminomatous germ-cell tumor. ( 19335332 )
2009
50
Cisplatin-based chemotherapy followed by surgery for malignant nonseminomatous germ cell tumor of mediastinum: one institution's experience. ( 19597926 )
2009
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Variations for Nonseminomatous Germ Cell Tumor

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Expression for Nonseminomatous Germ Cell Tumor

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Search GEO for disease gene expression data for Nonseminomatous Germ Cell Tumor.
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Pathways for Nonseminomatous Germ Cell Tumor

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Pathways related to Nonseminomatous Germ Cell Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors 67
Show member pathways
 10.59 CGB5 ERBB2
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GO Terms for Nonseminomatous Germ Cell Tumor

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Biological processes related to Nonseminomatous Germ Cell Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.16 CGB5 CGB7
2 hormone-mediated signaling pathway GO:0009755 8.96 CGB5 CGB7
3 female gamete generation GO:0007292 8.62 CGB5 CGB7
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Sources for Nonseminomatous Germ Cell Tumor

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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