MCID: NNS018
MIFTS: 30

Nonsyndromic Paraganglioma

Categories: Cancer diseases, Ear diseases, Endocrine diseases, Genetic diseases, Rare diseases

Aliases & Classifications for Nonsyndromic Paraganglioma

MalaCards integrated aliases for Nonsyndromic Paraganglioma:

Name: Nonsyndromic Paraganglioma 25
Extra-Adrenal Paraganglioma 71
Carotid Body Paraganglioma 71
Chemodectoma 25

Classifications:



External Ids:

UMLS 71 C0007279 C0030422

Summaries for Nonsyndromic Paraganglioma

Genetics Home Reference : 25 Paraganglioma is a type of noncancerous (benign) tumor that occurs in structures called paraganglia. Paraganglia are groups of cells that are found near nerve cell bunches called ganglia. Paragangliomas are usually found in the head, neck, or torso. However, a type of paraganglioma known as pheochromocytoma develops in the adrenal glands. Adrenal glands are located on top of each kidney and produce hormones in response to stress. Most people with paraganglioma develop only one tumor in their lifetime. Some people develop a paraganglioma or pheochromocytoma as part of a hereditary syndrome that may affect other organs and tissues in the body. However, the tumors often are not associated with any syndromes, in which case the condition is called nonsyndromic paraganglioma or pheochromocytoma. Pheochromocytomas and some other paragangliomas are associated with ganglia of the sympathetic nervous system. The sympathetic nervous system controls the "fight-or-flight" response, a series of changes in the body due to hormones released in response to stress. Although most sympathetic paragangliomas are pheochromocytomas, some are found outside the adrenal glands, usually in the abdomen, and are called extra-adrenal paragangliomas. Most sympathetic paragangliomas, including pheochromocytomas, produce hormones called catecholamines, such as epinephrine (adrenaline) or norepinephrine. These excess catecholamines can cause signs and symptoms such as high blood pressure (hypertension), episodes of rapid heartbeat (palpitations), headaches, or sweating. Most paragangliomas are associated with ganglia of the parasympathetic nervous system, which controls involuntary body functions such as digestion and saliva formation. Parasympathetic paragangliomas, typically found in the head and neck, usually do not produce hormones. However, large tumors may cause signs and symptoms such as coughing, hearing loss in one ear, or difficulty swallowing. Although most paragangliomas and pheochromocytomas are noncancerous, some can become cancerous (malignant) and spread to other parts of the body (metastasize). Extra-adrenal paragangliomas become malignant more often than other types of paraganglioma or pheochromocytoma.

MalaCards based summary : Nonsyndromic Paraganglioma, also known as extra-adrenal paraganglioma, is related to abdominal chemodectomas with cutaneous angiolipomas and chemodectoma, intraabdominal, with cutaneous angiolipomas. The drugs Epinephrine and Sirolimus have been mentioned in the context of this disorder. Affiliated tissues include adrenal gland, kidney and heart.

Related Diseases for Nonsyndromic Paraganglioma

Diseases in the Paraganglioma family:

Paragangliomas 4 Paragangliomas 1
Paragangliomas 2 Paragangliomas 3
Paragangliomas 5 Paragangliomas 6
Paragangliomas 7 Nonsyndromic Paraganglioma

Diseases related to Nonsyndromic Paraganglioma via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 79, show less)
# Related Disease Score Top Affiliating Genes
1 abdominal chemodectomas with cutaneous angiolipomas 12.5
2 chemodectoma, intraabdominal, with cutaneous angiolipomas 12.3
3 non-secreting chemodectoma 12.2
4 paragangliomas 1 12.2
5 paraganglioma 11.9
6 glomus tumor 10.5
7 rare tumor 10.4
8 pheochromocytoma 10.3
9 adrenal gland pheochromocytoma 10.3
10 pericarditis 10.2
11 hemangioma 10.2
12 osteochondroma 10.2
13 ocular motor apraxia 10.1
14 horner's syndrome 10.1
15 goiter 10.1
16 neurilemmoma 10.1
17 cranial nerve palsy 10.1
18 paraplegia 10.1
19 adenoma 10.1
20 carotid body cancer 10.1
21 exophthalmos 10.1
22 back pain 10.1
23 dysphagia 10.1
24 hypoxia 10.1
25 thyroid carcinoma 10.1
26 hepatocellular carcinoma 9.9
27 lipomatosis, multiple 9.9
28 otitis media 9.9
29 sarcoidosis 1 9.9
30 thrombophilia due to thrombin defect 9.9
31 thyroid cancer, nonmedullary, 1 9.9
32 angiolipomatosis, familial 9.9
33 congenital heart defects, hamartomas of tongue, and polysyndactyly 9.9
34 myasthenia gravis 9.9
35 thymoma, familial 9.9
36 branchiootic syndrome 1 9.9
37 meningioma, radiation-induced 9.9
38 meningioma, familial 9.9
39 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 9.9
40 deficiency anemia 9.9
41 atrioventricular block 9.9
42 third-degree atrioventricular block 9.9
43 extra-adrenal pheochromocytoma 9.9
44 mucositis 9.9
45 pleomorphic lipoma 9.9
46 petrositis 9.9
47 spinal meningioma 9.9
48 hemopericardium 9.9
49 cardiac tamponade 9.9
50 cauda equina syndrome 9.9
51 pericardial effusion 9.9
52 conn's syndrome 9.9
53 leiomyoma 9.9
54 nodular goiter 9.9
55 diarrhea 9.9
56 hyperparathyroidism 9.9
57 hypothyroidism 9.9
58 neuroendocrine tumor 9.9
59 gangliocytoma 9.9
60 chondroma 9.9
61 thymoma 9.9
62 temporal lobe epilepsy 9.9
63 pituitary adenoma 9.9
64 thyroid gland papillary carcinoma 9.9
65 gastritis 9.9
66 secretory meningioma 9.9
67 lymphoplasmacyte-rich meningioma 9.9
68 ganglioneuroma 9.9
69 bronchitis 9.9
70 ceruminoma 9.9
71 hard palate cancer 9.9
72 47,xyy 9.9
73 baroreflex failure 9.9
74 cerebrospinal fluid leak 9.9
75 cutis verticis gyrata 9.9
76 single ventricular heart 9.9
77 multiple endocrine neoplasia 9.9
78 angiomatosis 9.9
79 argyria 9.9

Graphical network of the top 20 diseases related to Nonsyndromic Paraganglioma:



Diseases related to Nonsyndromic Paraganglioma

Symptoms & Phenotypes for Nonsyndromic Paraganglioma

Drugs & Therapeutics for Nonsyndromic Paraganglioma

Drugs for Nonsyndromic Paraganglioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 12, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Epinephrine Approved, Vet_approved Phase 2 51-43-4 5816
2
Sirolimus Approved, Investigational Phase 2 53123-88-9 5284616 6436030 46835353
3
Everolimus Approved Phase 2 159351-69-6 6442177 70789204
4
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
5
Racepinephrine Approved Phase 2 329-65-7 838
6 Epinephryl borate Phase 2
7 Anti-Infective Agents Phase 2
8 Antibiotics, Antitubercular Phase 2
9 Anti-Bacterial Agents Phase 2
10 Antifungal Agents Phase 2
11 Immunosuppressive Agents Phase 2
12 Immunologic Factors Phase 2

Interventional clinical trials:

(showing 2, show less)
# Name Status NCT ID Phase Drugs
1 Phase II Study of RAD001monotherapy in Patients With Unresectable Pheochromocytoma or Extra-adrenal Paraganglioma or Non-functioning Carcinoid Completed NCT01152827 Phase 2 RAD001
2 A Phase 2 Study of Pazopanib (GW786034) in Patients With Advanced and Progressive Malignant Pheochromocytoma or Paraganglioma Terminated NCT01340794 Phase 2 Pazopanib Hydrochloride

Search NIH Clinical Center for Nonsyndromic Paraganglioma

Genetic Tests for Nonsyndromic Paraganglioma

Anatomical Context for Nonsyndromic Paraganglioma

MalaCards organs/tissues related to Nonsyndromic Paraganglioma:

40
Adrenal Gland, Kidney, Heart, Thyroid, Lung, Testes, Cortex

Publications for Nonsyndromic Paraganglioma

Articles related to Nonsyndromic Paraganglioma:

(showing 150, show less)
# Title Authors PMID Year
1
Prospective evaluation of 68Ga-DOTANOC positron emission tomography/computed tomography and 131I-meta-iodobenzylguanidine single-photon emission computed tomography/computed tomography in extra-adrenal paragangliomas, including uncommon primary sites and to define their diagnostic roles in current scenario. 61
31633647 2019
2
Ligament-Saving Laminoplasty for Intraspinal Tumor Excision: A Technical Note. 61
31103766 2019
3
Laparoscopic resection of retroperitoneal paraganglioma behind the Spiegel lobe in a kyphotic patient: A rare case report. 61
30015378 2019
4
68Ga-DOTATOC PET/CT in the localization of metastatic extra-adrenal paraganglioma and pheochromocytoma compared with 18F-DOPA PET/CT. 61
30630744 2019
5
Orbital paraganglioma in a dog. 61
30658369 2018
6
Immediate Clinical Success After Percutaneous Ablation of Extra-adrenal Paraganglioma. 61
29922859 2018
7
Diagnosis of paraganglioma as a pancreatic mass: A case report. 61
29882285 2018
8
Extra-adrenal paraganglioma masquerading as severe preeclampsia. 61
30018907 2018
9
Posterior Retroperitoneoscopic Resection of Extra-adrenal Paraganglioma Located in the Aorto-caval Space. 61
29330717 2018
10
Functional Ulnar Nerve Paraganglioma: First Documented Occurrence in the Extremity With Hitherto Undescribed Associated Extensive Glomus Cell Hyperplasia and Tumorlet Formation. 61
28697655 2018
11
Clinical evaluation and treatment of phaeochromocytoma. 61
29027806 2018
12
MR imaging features of benign retroperitoneal paragangliomas and schwannomas. 61
29301496 2018
13
68Ga-DOTA-TATE PET/CT for Molecular Imaging of Somatostatin Receptor Expression in Extra-adrenal Paraganglioma in a Case of Complete Carney Triad. 61
29076898 2017
14
Peripancreatic paraganglioma mimics pancreatic/gastrointestinal neuroendocrine tumor on fine needle aspiration: Report of two cases and review of the literature. 61
28560856 2017
15
Extra-adrenal pheochromocytoma at the organ of Zuckerkandl: a case report and literature review. 61
28491185 2017
16
Compared to 123I-MIBG SPECT/CT, 18F-DOPA PET/CT provides accurate tumor extent in patients with extra-adrenal paraganglioma. 61
28349331 2017
17
Challenging differential diagnosis of an extra-adrenal paraganglioma; the role of fine needle aspiration cytology. 61
28261927 2017
18
[Carney triad: Report of one case]. 61
28749001 2017
19
Pheochromocytoma of the Organ Zuckerkandl. 61
28414676 2017
20
A phase I clinical trial for [131I]meta-iodobenzylguanidine therapy in patients with refractory pheochromocytoma and paraganglioma: a study protocol. 61
28954983 2017
21
[Carney triad]. 61
28931294 2017
22
Malignant extra-adrenal pelvic paraganglioma in a paediatric patient. 61
28900474 2017
23
Functional extra-adrenal paraganglioma of the retroperitoneum giving thoracolumbar spine metastases after a five-year disease-free follow-up: a rare malignant condition with challenging management. 61
29255564 2017
24
An unusual case of incomplete Carney triad: an 18-year-old girl suffering from multiple benign tumors. 61
27867588 2016
25
Sudden Death and an Extra-Adrenal Paraganglioma. 61
31239903 2016
26
Imaging findings of malignant bilateral carotid body tumors: A case report and review of the literature. 61
27073498 2016
27
Primary pancreatic paraganglioma: a case report and literature review. 61
26801079 2016
28
Pelvic paraganglioma: a rare and unusual clinical presentation of paraganglioma. 61
26740269 2016
29
Sporadic paraganglioma caused by de novo SDHB mutations in a 6-year-old girl. 61
26283294 2016
30
A resected case of liver metastases from extra-adrenal retroperitoneal paraganglioma with von Recklinghausen's disease 16 years after the initial surgery. 61
26943413 2015
31
Carotid Body Tumor Presenting as Parotid Swelling Misdiagnosed as Pleomorphic Adenoma: A Rare Presentation. 61
26425073 2015
32
Multifocal Extra-Adrenal Paraganglioma - Case Report. 61
26351793 2015
33
Comparison of 131I-MIBG, 68Ga-DOTANOC PET/CT and 18F-FDG PET/CT scans in a patient with extra adrenal paraganglioma associated with SDH-B gene mutation. 61
25742231 2015
34
A case of carotid body tumor concomitant with carcinoid tumor. 61
25199739 2015
35
Paraganglioma Presenting as Postpartum Fever of Unknown Origin. 61
26236513 2015
36
Combined PET/CT by 18F-FDOPA, 18F-FDA, 18F-FDG, and MRI correlation on a patient with Carney triad. 61
25423347 2015
37
Extra-adrenal paraganglioma of the median nerve. 61
23750845 2014
38
Gastric paraganglioma: a case report and a review of the literature. 61
25559752 2014
39
Extra-adrenal paraganglioma presenting as acute chest pain mimicking acute myocardial infarction in a 10-year-old boy. 61
25373568 2014
40
Recurrent malignant pheochromocytoma with unusual omental metastasis: (68)Ga-DOTANOC PET/CT and (131)I-MIBG SPECT/CT scintigraphy findings. 61
25400380 2014
41
Rare extra-adrenal paraganglioma mimicking a painful Schwannoma: case report. 61
25285725 2014
42
Remission of a renal artery stenosis after laparoscopic removal of an extra adrenal paraganglioma. 61
25015630 2014
43
Primary Retroperitoneal Inter-aorto-Caval Paraganglioma of the Organ of Zuckerkandl. 61
25177602 2014
44
Cytomorphologic spectrum in aspirates of extra-adrenal paraganglioma. 61
25210234 2014
45
Non-functioning Aortocaval Paraganglioma Masquerading as Celiac Lymphnodal Metastasis. 61
25610296 2014
46
Unrecognized paraganglioma of the urinary bladder as a cause for basilar-type migraine. 61
23735539 2014
47
Anesthetic management of a patient with undiagnosed paraganglioma -a case report-. 61
24427467 2013
48
A retrospective comparison between 68Ga-DOTA-TOC PET/CT and 18F-DOPA PET/CT in patients with extra-adrenal paraganglioma. 61
24072345 2013
49
Multifocal extra-adrenal paraganglioma evaluated with different PET tracers: comparison between 18F-FDG, 18F-DOPA and 68Ga DOTANOC PET/CT. 61
23486329 2013
50
Extra-adrenal retroperitoneal paraganglioma in a dog. 61
24105380 2013
51
Adrenal cortical adenoma: the fourth component of the Carney triad and an association with subclinical Cushing syndrome. 61
23681078 2013
52
Hepatic paraganglioma and multifocal gastrointestinal stromal tumor in a female: Incomplete Carney triad. 61
23894692 2013
53
Extra-adrenal paraganglioma of the prostate. 61
23766843 2013
54
Retroperitoneal paraganglioma with metastasis to the abdominal vertebra: a case report. 61
23537060 2013
55
Diagnostic tests and biomarkers for pheochromocytoma and extra-adrenal paraganglioma: from routine laboratory methods to disease stratification. 61
22180288 2012
56
Distinct deregulation of the hypoxia inducible factor by PHD2 mutants identified in germline DNA of patients with polycythemia. 61
21933857 2012
57
Cardiac paraganglioma and gastrointestinal stromal tumor: a pediatric case of Carney-Stratakis syndrome. 61
22051283 2011
58
Paraganglioma of the oropharynx. 61
23024953 2011
59
Recent advances in the genetics of SDH-related paraganglioma and pheochromocytoma. 61
21082267 2011
60
Update on tumours of the adrenal cortex, phaeochromocytoma and extra-adrenal paraganglioma. 61
20718871 2011
61
Secondary hypertension: A rare cause. 61
21584168 2011
62
[Hereditary and non-hereditary syndromic gastointestinal stromal tumours]. 61
20848108 2010
63
Clinical, radiologic and pathologic characteristics of the Carney triad: a case report and literature review. 61
20705254 2010
64
[A case of giant retroperitoneal paraganglioma]. 61
20724811 2010
65
Asymptomatic extra-adrenal paraganglioma masquerading as retroperitoneal sarcoma. 61
26189900 2010
66
Images for diagnosis. An unusual case of Carney triad with high level catecholamine-secreting but no existence of extra-adrenal paraganglioma. 61
20193497 2010
67
Gastric stromal tumors in Carney triad are different clinically, pathologically, and behaviorally from sporadic gastric gastrointestinal stromal tumors: findings in 104 cases. 61
19935059 2010
68
A decade of clinical experience with extra-adrenal paragangliomas of retroperitoneum: Report of 67 cases and a literature review. 61
20842251 2010
69
Local-regional recurrence of sporadic or syndromic abdominal extra-adrenal paraganglioma: incidence, characteristics, and outcome. 61
19958924 2009
70
Carney triad in an adult with aggressive behavior: the first case in Korea. 61
19881977 2009
71
Incomplete Carney triad--a review of two cases. 61
19561114 2009
72
RET expression and neuron-like differentiation of pheochromocytoma and normal chromaffin cells. 61
19551609 2009
73
Management of carotid body tumors and familial paragangliomas: review of 30 years' experience. 61
19747612 2009
74
Extra-adrenal paraganglioma of the equine orbit: six cases. 61
19604344 2009
75
Extra-adrenal paraganglioma: presentation in three uncommon locations. 61
19694315 2009
76
Retroperitoneal extra-adrenal paraganglioma: a rare but important diagnosis. 61
18183473 2009
77
Renal hilus paraganglioma: a case report and brief review. 61
19886555 2009
78
Pheochromocytoma and extra-adrenal paraganglioma: updates. 61
18684026 2008
79
Malignant mediastinal extra-adrenal paraganglioma with spinal cord invasion in a dog. 61
18460631 2008
80
Carotid body tumor in a 13-year-old child: Case report and review of the literature. 61
18280094 2008
81
Extra-adrenal retroperitoneal paraganglioma associated with duplication of inferior vena cava. 61
22470594 2008
82
Paraganglioma of the mesenterium: a case report. 61
18188923 2007
83
Epithelioid gastric stromal tumours of the antrum in young females with the Carney triad: a report of three new cases with mutational analysis and comparative genomic hybridization. 61
17549339 2007
84
Malignant paragangliomas associated with mutations in the succinate dehydrogenase D gene. 61
17227803 2007
85
Pathology of pheochromocytoma and extra-adrenal paraganglioma. 61
17102124 2006
86
Extra-adrenal nonfunctional retroperitoneal paraganglioma: case report and review of the literature. 61
16625946 2005
87
[Carney's triad: a new case]. 61
16229813 2005
88
Interventional radiology in Carney triad. 61
15108016 2005
89
Dual CD117 expression in gastrointestinal stromal tumor (GIST) and paraganglioma of Carney triad: a case report. 61
15735861 2005
90
Increased prevalence of catecholamine excess and phaeochromocytomas in a well-defined Dutch population with SDHD-linked head and neck paragangliomas. 61
15762191 2005
91
Massive cardiac chondroma presenting with heart failure and superior vena cava obstruction in a teenage boy. 61
16137169 2004
92
Separate occurrence of extra-adrenal paraganglioma and gastrointestinal stromal tumor in monozygotic twins: probable familial Carney syndrome. 61
15383933 2004
93
An unusual mesenteric paraganglioma producing human chorionic gonadotropin. 61
15237592 2004
94
A pitfall of metaiodobenzylguanidine scan: paraganglioma in close proximity to adrenocortical adenoma. 61
12951637 2003
95
A comparison of biochemical tests for pheochromocytoma: measurement of fractionated plasma metanephrines compared with the combination of 24-hour urinary metanephrines and catecholamines. 61
12574179 2003
96
Multiple chondromatous hamartomas of the lung. 61
17669965 2002
97
The importance of renal localization with MIBG scintigraphy. 61
12072772 2002
98
Abdominal and pelvic extra-adrenal paraganglioma: a review of literature and a report on 7 cases. 61
12224134 2002
99
Mesenteric paraganglioma: a case report and review of the literature. 61
11860316 2002
100
Multifocal malignant extra-adrenal paragangliomas of the Organ of Zuckerkandl and urinary bladder. 61
11380371 2001
101
[Radiology of gastrointestinal stromal tumors (GIST) and a case of Carney syndrome]. 61
10778462 2000
102
Laparoscopic intraoperative ultrasonic localization and resection of an extra-adrenal pheochromocytoma. 61
10632514 1999
103
A case of the Carney triad. 61
15251665 1999
104
Gastric stromal sarcoma, pulmonary chondroma, and extra-adrenal paraganglioma (Carney Triad): natural history, adrenocortical component, and possible familial occurrence. 61
10377927 1999
105
Multiple chondromatous hamartomas of the lung: a case report and review of the literature with special reference to Carney syndrome. 61
10375102 1999
106
Searching for an intrinsic neuroendocrine cell in the kidney. An immunohistochemical study of the fetal, infantile and adult kidney. 61
10048091 1999
107
[Extra-adrenal retroperitoneal paraganglioma]. 61
9656564 1998
108
Loss of heterozygosity on the short arm of chromosomes 1 and 3 in sporadic pheochromocytoma and extra-adrenal paraganglioma. 61
9104939 1997
109
Magnetic resonance imaging of Carney's triad. 61
8091266 1994
110
Carney syndrome: radiologic features. 61
8149274 1994
111
[Bladder paraganglioma]. 61
8237531 1993
112
Metastasizing extra-adrenal paraganglioma with neurological signs in four dogs. 61
8315056 1993
113
Leiomyosarcoma of the stomach: determinants of long-term survival. 61
1434880 1992
114
[Carney's triad: a short review apropos a case]. 61
1620943 1992
115
Catecholamine synthesizing enzymes in 70 cases of functioning and non-functioning phaeochromocytoma and extra-adrenal paraganglioma. 61
1353277 1992
116
[Functioning extra-adrenal paragangliomas]. 61
2177858 1990
117
Carney's triad with recurrent gastric leiomyoblastoma. 61
2161630 1990
118
Extra-adrenal non-functioning paraganglioma. 61
2195728 1990
119
[Carney's triad. Apropos of a case of recurrent gastric leiomyosarcoma and bilateral pulmonary chondroma]. 61
2850598 1988
120
Cytomorphological description of an abdominal extra-adrenal paraganglioma in a Fischer 344 rat. 61
2851687 1988
121
Carney's triad: guidelines for management. 61
3361958 1988
122
Multiple organ metastasis of an aortic body tumor in a boxer. 61
2826374 1987
123
Extra-adrenal paraganglioma and pulmonary chondroma: a case report and review of the literature. 61
2884350 1987
124
Gastric autonomic nerve (GAN) tumor and extra-adrenal paraganglioma in Carney's triad. A common origin. 61
3827356 1987
125
Carney's triad: gastric leiomyosarcoma, pulmonary chondroma and extra-adrenal paraganglioma in young females. 61
3028925 1986
126
[Childhood retroperitoneal extra-adrenal paraganglioma, secretor of catecholamines, thyrocalcitonin and gastrin. An immunohistochemical and ultrastructural study]. 61
3784648 1986
127
[Importance of computed tomography in the diagnosis and differential diagnosis of primary adrenal tumors]. 61
2997871 1985
128
Gastric epitheloid leiomyomas, pulmonary chondroma, non-functioning metastasizing extra-adrenal paraganglioma and myxoma: a variant of Carney's triad. Report of a patient. 61
3990171 1985
129
Duodenal gangliocytic paraganglioma. An immunohistochemical and ultrastructural study and a hypothesis concerning its origin. 61
2578747 1985
130
[Concomitance of gastric epithelioid leiomyosarcoma, functional extra-adrenal paraganglioma and chondroma of the lung]. 61
6091984 1984
131
[The triad: mediastinal chemodectoma, chondroma of the lung and esophageal leiomyoma]. 61
6326247 1984
132
[Carney's triad]. 61
6320155 1984
133
Paraganglioma of urinary bladder. 61
6649239 1983
134
Carney's triad: role of transthoracic needle biopsy. 61
6309045 1983
135
Pulmonary metastatic leiomyosarcoma coexisting with pulmonary chondroma in Carney's triad. 61
6307197 1983
136
The triad of gastric epithelioid leiomyosarcoma, pulmonary chondroma, and functioning extra-adrenal paraganglioma: a five-year review. 61
6843355 1983
137
Pulmonary chondroma, extra-adrenal paraganglioma, and gastric leiomyosarcoma: Carney's triad. 61
6287121 1982
138
Immunoreactive somatostatin in catecholamine-producing extra-adrenal paraganglioma. 61
6124312 1982
139
Paraganglioma of the falciform ligament: a case report. 61
6954936 1982
140
[Extra-adrenal paraganglioma of the urinary bladder]. 61
6212515 1982
141
[Association of a gastric epithelioid leiomyosarcoma and a functioning extra-adrenal paraganglioma. A new case suggestive of a single syndrome]. 61
6291466 1982
142
Gastric tumors in patients with pulmonary chondroma or extra-adrenal paraganglioma: an ultrastructural study. 61
6895164 1981
143
Aorticopulmonary paraganglioma and gastric leiomyoblastoma in a young woman. 61
6263093 1981
144
[Paraganglioma of the glomus caroticum]. 61
424714 1979
145
The triad of gastric epithelioid leiomyosarcoma, functioning extra-adrenal paraganglioma, and pulmonary chondroma. 61
367573 1979
146
[Bronchopulmonary hamartomas, chondromas, fibromas and myxomas]. 61
204001 1978
147
[Clinico-pathological study of extra-adrenal paraganglioma (chemodectomas)]. 61
203000 1977
148
The triad of gastric leiomyosarcoma, functioning extra-adrenal paraganglioma and pulmonary chondroma. 61
865533 1977
149
Nonfunctional retroperitoneal extra-adrenal paraganglioma. Case report. 61
14907 1977
150
[Extra-adrenal paraganglioma located in the abdomen]. 61
13454525 1957

Variations for Nonsyndromic Paraganglioma

Cosmic variations for Nonsyndromic Paraganglioma:

9 (showing 113, show less)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM88301868 VHL adrenal gland,adrenal gland,pheochromocytoma,benign c.389T>G p.V130G 3:10146562-10146562 4
2 COSM88294143 VHL adrenal gland,adrenal gland,pheochromocytoma,benign c.260T>C p.V87A 3:10142107-10142107 4
3 COSM88293303 VHL adrenal gland,adrenal gland,pheochromocytoma,benign c.475A>G p.K159E 3:10149798-10149798 4
4 COSM88288959 VHL adrenal gland,adrenal gland,pheochromocytoma,benign c.482G>A p.R161Q 3:10149805-10149805 4
5 COSM88296074 VHL adrenal gland,adrenal gland,pheochromocytoma,benign c.250G>C p.V84L 3:10142097-10142097 4
6 COSM88292246 VHL adrenal gland,adrenal gland,pheochromocytoma,benign c.227T>A p.F76Y 3:10142074-10142074 4
7 COSM88292324 VHL adrenal gland,adrenal gland,pheochromocytoma,benign c.496G>T p.V166F 3:10149819-10149819 4
8 COSM88305342 VHL adrenal gland,adrenal gland,pheochromocytoma,benign c.492G>T p.Q164H 3:10149815-10149815 4
9 COSM88292236 VHL adrenal gland,adrenal gland,pheochromocytoma,benign c.491A>G p.Q164R 3:10149814-10149814 4
10 COSM92347003 RET adrenal gland,adrenal gland,pheochromocytoma,benign c.2753T>C p.M918T 10:43121968-43121968 4
11 COSM92347226 RET adrenal gland,adrenal gland,pheochromocytoma,benign c.1900T>C p.C634R 10:43114500-43114500 4
12 COSM93656552 NF1 adrenal gland,adrenal gland,pheochromocytoma,benign c.1885G>A p.G629R 17:31225134-31225134 4
13 COSM93692982 NF1 adrenal gland,adrenal gland,pheochromocytoma,benign c.5665G>T p.E1889* 17:31330351-31330351 4
14 COSM93650970 NF1 adrenal gland,adrenal gland,pheochromocytoma,benign c.1466A>G p.Y489C 17:31214524-31214524 4
15 COSM93662933 NF1 adrenal gland,adrenal gland,pheochromocytoma,benign c.7582C>T p.Q2528* 17:31352381-31352381 4
16 COSM93654948 NF1 adrenal gland,adrenal gland,pheochromocytoma,benign c.7646C>G p.S2549* 17:31356490-31356490 4
17 COSM93650764 NF1 adrenal gland,adrenal gland,pheochromocytoma,benign c.7300C>T p.Q2434* 17:31349230-31349230 4
18 COSM93652933 NF1 adrenal gland,adrenal gland,pheochromocytoma,benign c.205-1G>C p.? 17:31159009-31159009 4
19 COSM93668028 NF1 adrenal gland,adrenal gland,pheochromocytoma,benign c.1722-1G>A p.? 17:31223443-31223443 4
20 COSM93647950 NF1 adrenal gland,adrenal gland,pheochromocytoma,benign c.1721+3A>T p.? 17:31221932-31221932 4
21 COSM93688082 NF1 adrenal gland,adrenal gland,pheochromocytoma,benign c.6855C>A p.Y2285* 17:31338739-31338739 4
22 COSM93680586 NF1 adrenal gland,adrenal gland,pheochromocytoma,benign c.226G>T p.E76* 17:31159031-31159031 4
23 COSM93687360 NF1 adrenal gland,adrenal gland,pheochromocytoma,benign c.3158C>A p.S1053* 17:31230886-31230886 4
24 COSM93653832 NF1 adrenal gland,adrenal gland,pheochromocytoma,benign c.2409+1G>A p.? 17:31227607-31227607 4
25 COSM88844097 MET adrenal gland,adrenal gland,pheochromocytoma,benign c.3029C>T p.T1010I 7:116771936-116771936 4
26 COSM88849124 MET adrenal gland,adrenal gland,pheochromocytoma,benign c.607T>A p.S203T 7:116699691-116699691 4
27 COSM88850455 MET adrenal gland,adrenal gland,pheochromocytoma,benign c.352A>T p.M118L 7:116699436-116699436 4
28 COSM112988851 HRAS adrenal gland,adrenal gland,pheochromocytoma,benign c.182A>G p.Q61R 11:533874-533874 4
29 COSM112988925 HRAS adrenal gland,adrenal gland,pheochromocytoma,benign c.181C>A p.Q61K 11:533875-533875 4
30 COSM112988832 HRAS adrenal gland,adrenal gland,pheochromocytoma,benign c.37G>C p.G13R 11:534286-534286 4
31 COSM95516578 H3-3A adrenal gland,adrenal gland,pheochromocytoma,benign c.103G>T p.G35W 1:226064454-226064454 4
32 COSM107493928 FGFR1 adrenal gland,adrenal gland,pheochromocytoma,benign c.1731C>A p.N577K 8:38417331-38417331 4
33 COSM86761750 EPAS1 adrenal gland,adrenal gland,pheochromocytoma,benign c.1104G>A p.M368I 2:46376608-46376608 4
34 COSM86761419 EPAS1 adrenal gland,adrenal gland,pheochromocytoma,benign c.1589C>A p.A530E 2:46380261-46380261 4
35 COSM86757527 EPAS1 adrenal gland,adrenal gland,pheochromocytoma,benign c.1595A>G p.Y532C 2:46380267-46380267 4
36 COSM86759134 EPAS1 adrenal gland,adrenal gland,pheochromocytoma,benign c.1592C>T p.P531L 2:46380264-46380264 4
37 COSM93530486 adrenal gland,adrenal gland,pheochromocytoma,benign c.226G>T p.E76* 17:31159031-31159031 4
38 COSM91331163 adrenal gland,adrenal gland,pheochromocytoma,benign c.182A>G p.Q61R 11:533874-533874 4
39 COSM120509060 adrenal gland,adrenal gland,pheochromocytoma,benign c.1466A>G p.Y489C 17:31214524-31214524 4
40 COSM92696795 adrenal gland,adrenal gland,pheochromocytoma,benign c.*688C>A p.? 8:38417331-38417331 4
41 COSM93535461 adrenal gland,adrenal gland,pheochromocytoma,benign c.3158C>A p.S1053* 17:31230886-31230886 4
42 COSM101951610 adrenal gland,adrenal gland,pheochromocytoma,benign c.182A>G p.Q61R 11:533874-533874 4
43 COSM109968573 adrenal gland,adrenal gland,pheochromocytoma,benign c.226G>T p.E76* 17:31159031-31159031 4
44 COSM109960979 adrenal gland,adrenal gland,pheochromocytoma,benign c.1466A>G p.Y489C 17:31214524-31214524 4
45 COSM93512112 adrenal gland,adrenal gland,pheochromocytoma,benign c.1885G>A p.G629R 17:31225134-31225134 4
46 COSM90654925 adrenal gland,adrenal gland,pheochromocytoma,benign c.260T>C p.V87A 3:10142107-10142107 4
47 COSM105721394 adrenal gland,adrenal gland,pheochromocytoma,benign c.182A>G p.Q61R 11:533874-533874 4
48 COSM93508888 adrenal gland,adrenal gland,pheochromocytoma,benign c.205-1G>C p.? 17:31159009-31159009 4
49 COSM90652830 adrenal gland,adrenal gland,pheochromocytoma,benign c.373G>T p.V125F 3:10149819-10149819 4
50 COSM111018308 adrenal gland,adrenal gland,pheochromocytoma,benign c.352A>T p.M118L 7:116699436-116699436 4
51 COSM102553914 adrenal gland,adrenal gland,pheochromocytoma,benign c.2975C>T p.T992I 7:116771936-116771936 4
52 COSM93509879 adrenal gland,adrenal gland,pheochromocytoma,benign c.2409+1G>A p.? 17:31227607-31227607 4
53 COSM90811579 adrenal gland,adrenal gland,pheochromocytoma,benign c.2753T>C p.M918T 10:43121968-43121968 4
54 COSM95520543 adrenal gland,adrenal gland,pheochromocytoma,benign c.103G>T p.G35W 1:226064454-226064454 4
55 COSM120509488 adrenal gland,adrenal gland,pheochromocytoma,benign c.205-1G>C p.? 17:31159009-31159009 4
56 COSM100524124 adrenal gland,adrenal gland,pheochromocytoma,benign c.1632C>A p.N544K 8:38417331-38417331 4
57 COSM145650737 adrenal gland,adrenal gland,pheochromocytoma,benign c.*533C>A p.? 8:38417331-38417331 4
58 COSM142343426 adrenal gland,adrenal gland,pheochromocytoma,benign c.1289+3268T>C p.? 10:43114500-43114500 4
59 COSM93507010 adrenal gland,adrenal gland,pheochromocytoma,benign c.7237C>T p.Q2413* 17:31349230-31349230 4
60 COSM142343204 adrenal gland,adrenal gland,pheochromocytoma,benign c.*102T>C p.? 10:43121968-43121968 4
61 COSM101967275 adrenal gland,adrenal gland,pheochromocytoma,benign c.182A>G p.Q61R 11:533874-533874 4
62 COSM105721476 adrenal gland,adrenal gland,pheochromocytoma,benign c.181C>A p.Q61K 11:533875-533875 4
63 COSM95523461 adrenal gland,adrenal gland,pheochromocytoma,benign c.103G>T p.G35W 1:226064454-226064454 4
64 COSM93504734 adrenal gland,adrenal gland,pheochromocytoma,benign c.1721+3A>T p.? 17:31221932-31221932 4
65 COSM90249300 adrenal gland,adrenal gland,pheochromocytoma,benign c.1365C>A p.N455K 8:38417331-38417331 4
66 COSM100492971 adrenal gland,adrenal gland,pheochromocytoma,benign c.1371C>A p.N457K 8:38417331-38417331 4
67 COSM90652721 adrenal gland,adrenal gland,pheochromocytoma,benign c.368A>G p.Q123R 3:10149814-10149814 4
68 COSM91331132 adrenal gland,adrenal gland,pheochromocytoma,benign c.37G>C p.G13R 11:534286-534286 4
69 COSM105721363 adrenal gland,adrenal gland,pheochromocytoma,benign c.37G>C p.G13R 11:534286-534286 4
70 COSM95526780 adrenal gland,adrenal gland,pheochromocytoma,benign c.103G>T p.G35W 1:226064454-226064454 4
71 COSM93507162 adrenal gland,adrenal gland,pheochromocytoma,benign c.1466A>G p.Y489C 17:31214524-31214524 4
72 COSM120515658 adrenal gland,adrenal gland,pheochromocytoma,benign c.226G>T p.E76* 17:31159031-31159031 4
73 COSM90657160 adrenal gland,adrenal gland,pheochromocytoma,benign c.250G>C p.V84L 3:10142097-10142097 4
74 COSM112760290 adrenal gland,adrenal gland,pheochromocytoma,benign c.1638C>A p.N546K 8:38417331-38417331 4
75 COSM90811811 adrenal gland,adrenal gland,pheochromocytoma,benign c.1900T>C p.C634R 10:43114500-43114500 4
76 COSM90653943 adrenal gland,adrenal gland,pheochromocytoma,benign c.352A>G p.K118E 3:10149798-10149798 4
77 COSM90668341 adrenal gland,adrenal gland,pheochromocytoma,benign c.369G>T p.Q123H 3:10149815-10149815 4
78 COSM101951576 adrenal gland,adrenal gland,pheochromocytoma,benign c.37G>C p.G13R 11:534286-534286 4
79 COSM93517207 adrenal gland,adrenal gland,pheochromocytoma,benign c.7519C>T p.Q2507* 17:31352381-31352381 4
80 COSM100435279 adrenal gland,adrenal gland,pheochromocytoma,benign c.1632C>A p.N544K 8:38417331-38417331 4
81 COSM109960306 adrenal gland,adrenal gland,pheochromocytoma,benign c.1724A>T p.Y575F 17:31221932-31221932 4
82 COSM111017473 adrenal gland,adrenal gland,pheochromocytoma,benign c.607T>A p.S203T 7:116699691-116699691 4
83 COSM90652730 adrenal gland,adrenal gland,pheochromocytoma,benign c.227T>A p.F76Y 3:10142074-10142074 4
84 COSM93593372 adrenal gland,adrenal gland,pheochromocytoma,benign c.1371C>A p.N457K 8:38417331-38417331 4
85 COSM102561748 adrenal gland,adrenal gland,pheochromocytoma,benign c.352A>T p.M118L 7:116699436-116699436 4
86 COSM101951686 adrenal gland,adrenal gland,pheochromocytoma,benign c.181C>A p.Q61K 11:533875-533875 4
87 COSM109961525 adrenal gland,adrenal gland,pheochromocytoma,benign c.205-1G>C p.? 17:31159009-31159009 4
88 COSM93521551 adrenal gland,adrenal gland,pheochromocytoma,benign c.1722-1G>A p.? 17:31223443-31223443 4
89 COSM93540654 adrenal gland,adrenal gland,pheochromocytoma,benign c.5602G>T p.E1868* 17:31330351-31330351 4
90 COSM91331243 adrenal gland,adrenal gland,pheochromocytoma,benign c.181C>A p.Q61K 11:533875-533875 4
91 COSM102560105 adrenal gland,adrenal gland,pheochromocytoma,benign c.607T>A p.S203T 7:116699691-116699691 4
92 COSM93510966 adrenal gland,adrenal gland,pheochromocytoma,benign c.7583C>G p.S2528* 17:31356490-31356490 4
93 COSM93536022 adrenal gland,adrenal gland,pheochromocytoma,benign c.6792C>A p.Y2264* 17:31338739-31338739 4
94 COSM90648957 adrenal gland,adrenal gland,pheochromocytoma,benign c.359G>A p.R120Q 3:10149805-10149805 4
95 COSM101967342 adrenal gland,adrenal gland,pheochromocytoma,benign c.181C>A p.Q61K 11:533875-533875 4
96 COSM90664073 adrenal gland,adrenal gland,pheochromocytoma,benign c.341-3225T>G p.? 3:10146562-10146562 4
97 COSM100556615 adrenal gland,adrenal gland,pheochromocytoma,benign c.1632C>A p.N544K 8:38417331-38417331 4
98 COSM128210725 adrenal gland,adrenal gland,pheochromocytoma,benign c.1632C>A p.N544K 8:38417331-38417331 4
99 COSM90272895 adrenal gland,adrenal gland,pheochromocytoma,benign c.1608C>A p.N536K 8:38417331-38417331 4
100 COSM101967261 adrenal gland,adrenal gland,pheochromocytoma,benign c.37G>C p.G13R 11:534286-534286 4
101 COSM88291454 VHL adrenal gland,NS,pheochromocytoma,benign c.245G>T p.R82L 3:10142092-10142092 3
102 COSM88297427 VHL adrenal gland,NS,pheochromocytoma,benign c.244C>G p.R82G 3:10142091-10142091 3
103 COSM88289571 VHL adrenal gland,NS,pheochromocytoma,benign c.341-1G>T p.? 3:10146513-10146513 3
104 COSM88294223 VHL adrenal gland,NS,pheochromocytoma,benign c.499C>T p.R167W 3:10149822-10149822 3
105 COSM93650443 NF1 adrenal gland,NS,pheochromocytoma,benign c.1307C>A p.S436* 17:31206286-31206286 3
106 COSM86763051 EPAS1 adrenal gland,NS,pheochromocytoma,benign c.1601C>T p.P534L 2:46380273-46380273 3
107 COSM90658470 adrenal gland,NS,pheochromocytoma,benign c.244C>G p.R82G 3:10142091-10142091 3
108 COSM90651871 adrenal gland,NS,pheochromocytoma,benign c.245G>T p.R82L 3:10142092-10142092 3
109 COSM120508917 adrenal gland,NS,pheochromocytoma,benign c.1307C>A p.S436* 17:31206286-31206286 3
110 COSM90649980 adrenal gland,NS,pheochromocytoma,benign c.341-3274G>T p.? 3:10146513-10146513 3
111 COSM90655004 adrenal gland,NS,pheochromocytoma,benign c.376C>T p.R126W 3:10149822-10149822 3
112 COSM93506763 adrenal gland,NS,pheochromocytoma,benign c.1307C>A p.S436* 17:31206286-31206286 3
113 COSM109960796 adrenal gland,NS,pheochromocytoma,benign c.1307C>A p.S436* 17:31206286-31206286 3

Expression for Nonsyndromic Paraganglioma

Search GEO for disease gene expression data for Nonsyndromic Paraganglioma.

Pathways for Nonsyndromic Paraganglioma

GO Terms for Nonsyndromic Paraganglioma

Sources for Nonsyndromic Paraganglioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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