MCID: NSD001
MIFTS: 52

Nose Disease

Categories: Bone diseases, Respiratory diseases, Smell/Taste diseases

Aliases & Classifications for Nose Disease

MalaCards integrated aliases for Nose Disease:

Name: Nose Disease 12 15
Nose Diseases 45 74
Abnormality of the Nose 30
Disorder of the Nose 12
Nasal Disorder 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2825
MeSH 45 D009668
SNOMED-CT 69 89488007
ICD10 34 J33.9
UMLS 74 C0028432

Summaries for Nose Disease

MalaCards based summary : Nose Disease, also known as nose diseases, is related to vasomotor rhinitis and sinusitis, and has symptoms including dyspnea, apnea and rhinorrhea. An important gene associated with Nose Disease is RNASE3 (Ribonuclease A Family Member 3), and among its related pathways/superpathways are Innate Immune System and TGF-Beta Pathway. The drugs Clavulanate and Amoxicillin have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and lung, and related phenotypes are hematopoietic system and digestive/alimentary

Wikipedia : 77 The human nose is the most protruding part of the face that bears the nostrils and is the first organ of... more...

Related Diseases for Nose Disease

Diseases related to Nose Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 217)
# Related Disease Score Top Affiliating Genes
1 vasomotor rhinitis 30.2 RNASE3 TAC1
2 sinusitis 29.8 CXCL8 CYSLTR1 IL5 RNASE3
3 rhinitis 28.6 CCL11 CXCL8 CYSLTR1 HRH1 ICAM1 IL13
4 allergic rhinitis 28.5 CCL11 CXCL8 HRH1 ICAM1 IL10 IL13
5 fraser syndrome 1 10.8
6 bosma arhinia microphthalmia syndrome 10.8
7 parasitic ichthyosporea infectious disease 10.6 IL4 RHNO1
8 rhinosporidiosis 10.6 IL4 RHNO1
9 respiratory syncytial virus infectious disease 10.6 IL13 IL5
10 prurigo nodularis 10.5 RNASE3 TAC1
11 mikulicz disease 10.5 IL5 PTGDR2
12 ascaridiasis 10.5 IL10 IL13
13 bullous pemphigoid 10.5 CCL11 IL5 RNASE3
14 tracheitis 10.5 RHNO1 TNF
15 cough variant asthma 10.4 IL4 IL5 RNASE3
16 atopic keratoconjunctivitis 10.4 IL4 IL5 RNASE3
17 intrinsic asthma 10.4 IL4 IL5 RNASE3
18 neurosyphilis 10.4 CXCL8 IL10
19 paragonimiasis 10.4 IL13 IL5 RNASE3
20 acute transverse myelitis 10.4 CXCL8 IL10
21 pouchitis 10.4 CXCL8 IL10
22 cytokine deficiency 10.4 IL13 IL5
23 leiomyoma cutis 10.4 ICAM1 TAC1
24 blepharoconjunctivitis 10.4 CCL11 IL4 RNASE3
25 vernal conjunctivitis 10.4 IL4 MS4A2 RNASE3
26 intestinal schistosomiasis 10.4 IL13 IL4 IL5
27 chronic tic disorder 10.4 IL13 IL4 IL5
28 transient hypogammaglobulinemia 10.4 IL10 TNF
29 multifocal choroiditis 10.4 IL10 TNF
30 herpes simplex virus keratitis 10.4 CXCL8 ICAM1
31 strongyloidiasis 10.4 CCL11 IL13 IL5
32 enterobiasis 10.4 IL13 IL4 IL5
33 ascaris lumbricoides infection 10.4 IL13 IL5 TSLP
34 streptococcal toxic-shock syndrome 10.4 CXCL8 TNF
35 night blindness, congenital stationary, type 1a 10.4 CCL11 IL13 IL5
36 gaucher disease, type ii 10.4 IL10 IL4 IL5
37 filarial elephantiasis 10.4 IL10 IL4 IL5
38 papillary conjunctivitis 10.4 CCL11 CXCL8 IL4
39 beta-lactam allergy 10.4 IL10 IL13 IL4
40 inflammatory bowel disease 4 10.4 IL13 IL4 IL5 RNASE3
41 latex allergy 10.4 IL13 IL4 IL5 RNASE3
42 status asthmaticus 10.4 CXCL8 IL5 RNASE3
43 urinary schistosomiasis 10.4 IL13 IL4 IL5 RNASE3
44 loeffler endocarditis 10.3 IL5 RNASE3
45 cephalosporin allergy 10.3 IL10 IL5
46 wells syndrome 10.3 CXCL8 IL5 RNASE3
47 eosinophilic pneumonia 10.3 CCL11 IL13 IL5 RNASE3
48 angiostrongyliasis 10.3 CCL11 IL13 IL4 IL5
49 eosinophilic gastroenteritis 10.3 CCL11 IL5 RNASE3 TSLP
50 eosinophilic gastritis 10.3 CCL11 IL13 IL4 IL5

Graphical network of the top 20 diseases related to Nose Disease:



Diseases related to Nose Disease

Symptoms & Phenotypes for Nose Disease

UMLS symptoms related to Nose Disease:


dyspnea, apnea, rhinorrhea

MGI Mouse Phenotypes related to Nose Disease:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.93 CCL11 CHD7 HRH1 ICAM1 IL10 IL13
2 digestive/alimentary MP:0005381 9.86 CHD7 ICAM1 IL10 IL13 IL4 IL5
3 immune system MP:0005387 9.77 CCL11 CHD7 CYSLTR1 HRH1 ICAM1 IL10
4 respiratory system MP:0005388 9.28 CCL11 CHD7 CYSLTR1 IL10 IL13 IL4

Drugs & Therapeutics for Nose Disease

Drugs for Nose Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 538)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clavulanate Approved, Vet_approved Phase 4,Phase 3,Not Applicable 58001-44-8 5280980
2
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 26787-78-0 33613
3 Strawberry Approved Phase 4,Phase 3
4
Cefditoren Approved, Investigational Phase 4 117467-28-4, 104145-95-1 9571074 9870843
5
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 124-94-7 31307
6
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-45-6 774
7
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 90-82-4 7028
8
Azelastine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 58581-89-8 2267
9
mometasone furoate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 83919-23-7
10
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 83-43-2 6741
11
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3,Phase 2 2921-57-5
12
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 299-42-3 9294
13
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3,Phase 2 302-25-0
14
Xylometazoline Approved, Investigational Phase 4,Not Applicable 526-36-3 5709
15
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-24-8 5755
16
Fluticasone Approved, Experimental Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 90566-53-3 62924
17
Capsaicin Approved Phase 4,Phase 2,Phase 1 404-86-4 1548943
18
Lansoprazole Approved, Investigational Phase 4,Not Applicable 103577-45-3 3883
19
Dexlansoprazole Approved, Investigational Phase 4,Not Applicable 138530-94-6, 103577-45-3 9578005
20
Cetirizine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 83881-51-0 2678
21
Levocetirizine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 130018-77-8 1549000
22
Montelukast Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 158966-92-8 5281040
23
Rocuronium Approved Phase 4,Not Applicable 119302-91-9, 143558-00-3 441290
24
Remifentanil Approved Phase 4 132875-61-7 60815
25
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
26
Metoprolol Approved, Investigational Phase 4 37350-58-6, 51384-51-1 4171
27
Nitric Oxide Approved Phase 4,Phase 1,Phase 2,Not Applicable 10102-43-9 145068
28
Budesonide Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51333-22-3 63006 5281004
29
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 137-58-6 3676
30
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable 53-03-2 5865
31
Racepinephrine Approved Phase 4,Phase 3,Phase 2,Not Applicable 329-65-7 838
32
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 51-43-4 5816
33
Loratadine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 79794-75-5 3957
34
Desloratadine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 100643-71-8 124087
35
Oxymetazoline Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1491-59-4 4636
36
Phenylephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 59-42-7 6041
37
Betamethasone Approved, Vet_approved Phase 4,Phase 3 378-44-9 9782
38
Omalizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 242138-07-4
39
Bevacizumab Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 216974-75-3
40
Ketamine Approved, Vet_approved Phase 4,Not Applicable 6740-88-1 3821
41
Azithromycin Approved Phase 4,Phase 3,Phase 2,Not Applicable 83905-01-5 55185 447043
42
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2 564-25-0 54671203
43
Dopamine Approved Phase 4,Phase 3,Phase 2 62-31-7, 51-61-6 681
44
Cocaine Approved, Illicit Phase 4 50-36-2 446220 5760
45
Propofol Approved, Investigational, Vet_approved Phase 4,Not Applicable 2078-54-8 4943
46
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
47
Norgestimate Approved, Investigational Phase 4,Phase 3 35189-28-7 6540478
48
Moxifloxacin Approved, Investigational Phase 4,Phase 3 354812-41-2, 151096-09-2 152946
49
Polyestradiol phosphate Approved Phase 4,Phase 3 28014-46-2
50
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3 50-28-2 5757

Interventional clinical trials:

(show top 50) (show all 1434)
# Name Status NCT ID Phase Drugs
1 Middle Meatal Bacteriology During Acute Respiratory Infection in Children Unknown status NCT00545961 Phase 4 placebo;amoxicillin clavulanate acid
2 Study of Cefditoren Pivoxil in Treatment of Childhood With Acute Rhinosinusitis Unknown status NCT01553006 Phase 4 cefditoren pivoxil
3 The Effectiveness of Nasal Corticosteroids Versus Placebo in Nasal Obstruction in Patients With Nasal Septal Deviation Unknown status NCT02877485 Phase 4 Triamcinolone Acetonide;Ayr saline nasal mist
4 4"S" - Seasonal Symptoms Suppression Study Unknown status NCT02557269 Phase 4 Xylometazoline - intranasal application;Azelastine - intranasal application;Mometasone furoate - intranasal application;Hydroxyl-propyl-methyl cellulose powder - intranasal application;Bilastine 20 mg;Prednisolone 5 mg
5 Evaluating Factors Involved in Dymista's Superior Clinical Efficacy to Fluticasone Propionate in the Treatment of Seasonal Allergic Rhinitis Unknown status NCT02402465 Phase 4 Placebo;Fluticasone propionate;Fluticasone/Azelastine nasal spray
6 Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic Rhinitis Unknown status NCT02288156 Phase 4 Capsaicin;placebo
7 The Relationship Between Gastroesophageal Reflux and Pediatric Rhinitis: Significance of Pale/Blue Colored Turbinate Unknown status NCT02278081 Phase 4 lansoprazole;placebo
8 AZELASTINE/FLUTICASONE (AZE/FLU) Nasal Spray on Symptom Control, Nasal Mediators and Nasal Hyperresponsiveness in Allergic Rhinitis (AR) Unknown status NCT02238353 Phase 4 azelastine + fluticasone;Placebo
9 Immunological Mechanisms of Oralair® in Patients With Seasonal Allergic Rhinitis Unknown status NCT02014623 Phase 4 Control
10 Cosalin® Monotherapy Versus Cosalin® and Xarlin® Combination Therapy Unknown status NCT01062139 Phase 4 Xarlin (Levocetirizine);Cosalin (Petasites hybridus CO2 extract)
11 Comparative Study of Sinol and Sinol-M in Patients With Congestion Due to Allergic Rhinitis Unknown status NCT00825656 Phase 4 Sinol or Sinol-M nasal spray
12 Singulair Use in Non-Allergic Rhinitis Eosinophil Syndrome (NARES) Unknown status NCT00406094 Phase 4 montelukast;placebo
13 A Prospective Randomised Controlled Trial of Management of Recurrent Nosebleeds in Children Unknown status NCT00390663 Phase 4
14 Remifentanil and Controlled Hypotension for Functional Endoscopic Sinus Surgery: Comparison With Tramadol and Metoprolol Unknown status NCT02484859 Phase 4 Remifentanil;Tramadol;Metoprolol
15 POLlinosis and Exhaled Breath Temperature Unknown status NCT01785394 Phase 4 5 grass allergen extract
16 Comparison of the Effect of Montelukast and Cetirizine on Allergic Inflammation in Children With Allergic Rhinitis Unknown status NCT00488176 Phase 4 montelukast;cetirizine;montelukast and cetirizine;placebo
17 Comparison of Daily Mometasone Furoate Nasal Spray Alone Versus a Combination With Montelukast for Treatment of Chronic Rhinosinusitis With Asthma After Functional Endoscopic Sinus Surgery Unknown status NCT02110654 Phase 4 Montelukast;mometasone furoate nasal spray
18 Assessment of Sublingual Immunotherapy in Children Allergic to House Dust Mites Unknown status NCT01052610 Phase 4 sublingual house dust mites allergen extract;placebo in sublingual applicator
19 The Efficacy and Safety of Hyeonggaeyeongyo-tang for Chronic Rhinitis According to Pattern Identification in Korean Medicine Completed NCT02477293 Phase 4 Hyeonggaeyeongyo-tang
20 The Optimal Head Position for Distributing Topical Nasal Medication Using the Mucosal Atomization Device Completed NCT02079792 Phase 4
21 Fluticasone and Salmeterol in Allergic Rhinitis Completed NCT01388595 Phase 4 FLUTICASONE PROPRIONATE;Salmeterol;PLACEBO
22 Fluticasone Furoate Treatment of Daytime Somnolence and Cognitive Performance in Seasonal Allergic Rhinitis Completed NCT00997620 Phase 4 Fluticasone furoate Nasal Spray 110 mcg;Placebo
23 Effect of Ketamine Addition to Lidocaine in Rhinoplasty Completed NCT01827020 Phase 4 Lidocaine 2 %;Ketamine plus Lidocaine;Saline
24 Evaluation Of Cloumella Strut Effect In Tip Rotation Completed NCT00467714 Phase 4
25 Mechanisms of Capsaicin Treatment in Idiopathic Rhinitis Patients and Controls Completed NCT01862523 Phase 4
26 Neuro-immunological Analysis of Idiopathic Rhinitis Patients and Controls Treated With Capsaicin. Completed NCT01223820 Phase 4 Capsaicin
27 Safety and Efficacy of Olopatadine 0.6% and Azelastine 137 Mcg in Vasomotor Rhinitis Completed NCT00979615 Phase 4 Olopatadine HCL (Patanase) Nasal Spray, 0.6%;Azelastine HCl (Astelin) Nasal Spray, 137 mcg
28 The PIO II Study: In-office Post-op Placement of a Steroid-eluting Sinus Implant Completed NCT02668302 Phase 4
29 Clinical Trial of the Treatment of Acute Sinusitis With Standard-dose Versus High-dose Amoxicillin/Clavulanate Completed NCT02340000 Phase 4 standard dose amoxicillin/clavulanate;high dose amoxicillin/clavulanate
30 Azithromycin for Patients With Chronic Rhinosinusitis Failing Medical and Surgical Therapy Completed NCT02307825 Phase 4 Azithromycin;Placebo
31 Efficacy and Safety of Sinusitis Hevert SL Tablets Compared to Placebo in Adult Patients With Acute, Uncomplicated Rhinosinusitis Completed NCT02296814 Phase 4 Sinusitis Hevert SL Tablet;Placebo for Sinusitis Hevert SL Tablet
32 Prophylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Controlled Trial Completed NCT01919411 Phase 4 Amoxicillin-Potassium Clavulanate;Placebo
33 Medical Polypectomy and Predictors of Response Completed NCT00788749 Phase 4 Prednisolone;Placebo
34 Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis Completed NCT01825408 Phase 4 Doxycycline;Azithromycin;Augmentin
35 Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery Completed NCT01706952 Phase 4 Cocaine;Adrenaline
36 Saline Irrigation After Surgery in Patients With Chronic Sinusitis Completed NCT01575223 Phase 4
37 Randomized Controlled Trial to Evaluate of Dexmedetomidine for the Effect on Operative Visibility in Patients Undergoing Endoscopic Sinus Surgery Completed NCT01569048 Phase 4 Propofol and dexmedetomidine;propofol and remifentanil
38 Medicated Punctured-Glove-Finger Spacer Study Completed NCT01420471 Phase 4 Triamcinolone
39 Systemic Methylprednisolone in Chronic Rhinosinusitis Completed NCT01205984 Phase 4 methylprednisolone
40 Sinuclean's Treatment Of Sinusitis' Symptoms Completed NCT00747747 Phase 4
41 Trial to Evaluate Time to Symptom Relief and Elimination of Infecting Bacteria in Treating Sinusitis With Avelox Completed NCT00668304 Phase 4 Avelox (Moxifloxacin, BAY12-8039)
42 Study of the Safety and Efficacy of Cefdinir and Levofloxacin for the Treatment of Subjects With Acute Bacterial Sinusitis Completed NCT00645073 Phase 4 cefdinir (Omnicef);levofloxacin
43 Study to Evaluate Safety and Effectiveness of AdvaCoat Sinus Gel Completed NCT00554190 Phase 4
44 Use of Probiotics as Adjunctive Treatment for Chronic Rhinosinusitis Completed NCT00396162 Phase 4 probiotic containing L.rhamnosus R0011 strain
45 Treatment of Acute Sinusitis Completed NCT00377403 Phase 4 Acetaminophen;Amoxicillin;Dextromethorphan hydrobromide with guaifenesin;Guaifenesin;Pseudoephedrine Sustained Action;Saline spray (0.65%)
46 Zmax Compared to Augmentin in Sinusitis Completed NCT00367120 Phase 4 Azithromycin Extended Release;Amoxicillin/Clavulanate
47 Hemostatic Matrix in Endoscopic Sinus Surgery Completed NCT00242437 Phase 4
48 CHOOSE : Telithromycin, Acute Bacterial Sinusitis Completed NCT00174694 Phase 4 Telithromycin
49 Comparison Study Between Cefdinir & Amoxicilline/Clavulanate in Acute Sinusitis and Assessment of Quality of Life Completed NCT00147914 Phase 4 Cefdinir (drug);amoxicillin/clavulanate
50 Systemic Corticosteroids in the Perioperative Management of Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) Completed NCT02119273 Phase 4 Prednisone;Placebo

Search NIH Clinical Center for Nose Disease

Cochrane evidence based reviews: nose diseases

Genetic Tests for Nose Disease

Genetic tests related to Nose Disease:

# Genetic test Affiliating Genes
1 Abnormality of the Nose 30

Anatomical Context for Nose Disease

MalaCards organs/tissues related to Nose Disease:

42
Testes, Skin, Lung, Bone, Eye, Pituitary, Colon

Publications for Nose Disease

Articles related to Nose Disease:

# Title Authors Year
1
Hippocrates the otolaryngologist: an epidemiological analysis of ear-throat-nose diseases in the Corpus Hippocraticum. ( 29385936 )
2018
2
Blue nose disease in the horse. ( 18124494 )
1949

Variations for Nose Disease

Expression for Nose Disease

Search GEO for disease gene expression data for Nose Disease.

Pathways for Nose Disease

Pathways related to Nose Disease according to GeneCards Suite gene sharing:

(show all 44)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.01 CCL11 CXCL8 ICAM1 ICOSLG IL10 IL13
2
Show member pathways
13.51 CCL11 CXCL8 ICAM1 IL10 IL13 IL4
3
Show member pathways
13.38 CCL11 CXCL8 IL10 IL13 IL4 IL5
4
Show member pathways
13.33 CCL11 CXCL8 ICAM1 IL10 IL13 IL4
5
Show member pathways
13.26 CCL11 CXCL8 IL10 IL13 IL4 IL5
6
Show member pathways
12.6 ICOSLG IL10 IL4 MS4A2 TNF
7
Show member pathways
12.57 IL10 IL13 IL4 IL5 TNF
8
Show member pathways
12.56 IL13 IL4 IL5 MS4A2 TNF
9
Show member pathways
12.54 CXCL8 ICAM1 IL13 IL4 TNF
10
Show member pathways
12.44 CCL11 CXCL8 ICAM1 ICOSLG IL10 IL13
11
Show member pathways
12.38 IL10 IL4 IL5 TNF
12
Show member pathways
12.37 IL10 IL13 IL4 IL5 TSLP
13
Show member pathways
12.35 CCL11 CXCL8 IL13 IL4 IL5 TNF
14
Show member pathways
12.28 CXCL8 IL10 IL13 IL4 IL5 TNF
15 12.19 CXCL8 IL10 IL13 TAC1 TNF
16
Show member pathways
12.16 CCL11 CXCL8 IL4 TNF
17
Show member pathways
12.08 CCL11 CXCL8 ICAM1 IL10 IL13 IL4
18 12.01 IL10 IL4 IL5 PTGDR2 TNF
19 11.99 CXCL8 ICAM1 IL4 TNF
20 11.87 CXCL8 ICAM1 TNF
21 11.86 CCL11 CXCL8 ICAM1 IL10 IL13 IL4
22 11.85 IL4 IL5 TNF
23 11.84 CXCL8 IL10 TNF
24 11.83 CXCL8 ICAM1 TNF
25 11.81 CXCL8 ICAM1 TNF
26 11.81 CXCL8 ICAM1 IL13 IL4 IL5
27
Show member pathways
11.78 CXCL8 IL4 IL5 TNF
28 11.73 CCL11 IL10 IL13 IL4 TNF
29 11.72 CXCL8 IL10 TNF
30 11.68 CCL11 IL10 IL4 IL5
31
Show member pathways
11.63 CXCL8 ICAM1 TNF
32 11.6 CCL11 CXCL8 IL13 IL4 IL5 TNF
33 11.55 CXCL8 ICAM1 IL10 TNF
34 11.52 CCL11 IL10 IL13 IL4 IL5
35 11.49 CCL11 CXCL8 TSLP
36 11.37 ICAM1 IL10 TNF
37 11.32 CXCL8 ICAM1 IL10 IL13 IL4 TNF
38 11.31 IL13 IL4 IL5 TNF TSLP
39 11.23 IL10 IL13 IL4 IL5
40 11.23 IL10 IL13 IL4 IL5 TNF
41 11.21 CCL11 CXCL8 IL10 IL13 IL4 IL5
42 11.07 IL10 IL13 IL4 IL5 PTGDR2 TNF
43 11.01 CCL11 CXCL8 IL10 IL13 IL4 IL5
44 10.9 ICAM1 TNF

GO Terms for Nose Disease

Cellular components related to Nose Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.65 CCL11 CXCL8 IL10 IL13 IL4 IL5
2 external side of plasma membrane GO:0009897 9.55 ICAM1 ICOSLG IL13 MS4A2 TNF
3 extracellular space GO:0005615 9.36 CCL11 CXCL8 ICAM1 IL10 IL13 IL4

Biological processes related to Nose Disease according to GeneCards Suite gene sharing:

(show all 27)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.86 CCL11 CXCL8 IL10 IL13 IL4 IL5
2 response to lipopolysaccharide GO:0032496 9.84 ICAM1 IL10 IL13 TAC1
3 cellular response to lipopolysaccharide GO:0071222 9.83 CXCL8 ICAM1 IL10 TNF
4 neuropeptide signaling pathway GO:0007218 9.81 CYSLTR1 PTGDR2 TAC1
5 chemotaxis GO:0006935 9.81 CCL11 CXCL8 CYSLTR1 PTGDR2
6 immune response GO:0006955 9.81 CCL11 CXCL8 IL10 IL13 IL4 IL5
7 cellular response to interleukin-1 GO:0071347 9.77 CCL11 CXCL8 ICAM1
8 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.76 IL13 IL4 TSLP
9 defense response GO:0006952 9.76 CXCL8 CYSLTR1 ICOSLG TNF
10 negative regulation of growth of symbiont in host GO:0044130 9.63 IL10 TNF
11 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.62 IL10 TNF
12 negative regulation of endothelial cell apoptotic process GO:2000352 9.62 ICAM1 IL10 IL13 IL4
13 positive regulation of podosome assembly GO:0071803 9.61 IL5 TNF
14 response to molecule of bacterial origin GO:0002237 9.61 CXCL8 IL10
15 positive regulation of B cell proliferation GO:0030890 9.61 IL13 IL4 IL5
16 positive regulation of interleukin-13 production GO:0032736 9.59 IL4 TSLP
17 endothelial cell apoptotic process GO:0072577 9.58 IL10 TNF
18 positive regulation of MHC class II biosynthetic process GO:0045348 9.57 IL10 IL4
19 negative regulation of cytokine secretion involved in immune response GO:0002740 9.56 IL10 TNF
20 cytokine-mediated signaling pathway GO:0019221 9.56 CCL11 CXCL8 ICAM1 IL10 IL13 IL4
21 positive regulation of leukocyte adhesion to vascular endothelial cell GO:1904996 9.55 ICAM1 TNF
22 regulation of isotype switching GO:0045191 9.49 IL10 IL4
23 type 2 immune response GO:0042092 9.48 IL10 IL4
24 negative regulation of complement-dependent cytotoxicity GO:1903660 9.4 IL13 IL4
25 receptor biosynthetic process GO:0032800 9.37 IL10 TNF
26 inflammatory response GO:0006954 9.28 CCL11 CXCL8 HRH1 IL10 IL13 IL5
27 signal transduction GO:0007165 10.22 CCL11 CXCL8 CYSLTR1 HRH1 ICOSLG MS4A2

Molecular functions related to Nose Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.23 CCL11 CXCL8 IL10 IL13 IL4 IL5

Sources for Nose Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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