MCID: NSD001
MIFTS: 47

Nose Disease

Categories: Bone diseases, Respiratory diseases, Smell/Taste diseases

Aliases & Classifications for Nose Disease

MalaCards integrated aliases for Nose Disease:

Name: Nose Disease 12 15
Nose Diseases 44 73
Abnormality of the Nose 29
Disorder of the Nose 12
Nasal Disorder 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2825
MeSH 44 D009668
SNOMED-CT 68 89488007
ICD10 33 J33.9
UMLS 73 C0028432

Summaries for Nose Disease

MalaCards based summary : Nose Disease, also known as nose diseases, is related to vasomotor rhinitis and allergic rhinitis, and has symptoms including dyspnea, apnea and rhinorrhea. An important gene associated with Nose Disease is TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Amoxicillin and Strawberry have been mentioned in the context of this disorder. Affiliated tissues include bone, lung and skin, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 76 The human nose is the most protruding part of the face that bears the nostrils, and is the first organ... more...

Related Diseases for Nose Disease

Diseases related to Nose Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 250)
# Related Disease Score Top Affiliating Genes
1 vasomotor rhinitis 29.9 RNASE3 TAC1
2 allergic rhinitis 28.9 CCL11 CXCL8 HRH1 IL10 IL13 IL4
3 rhinitis 28.9 CCL11 CXCL8 CYSLTR1 HRH1 IL13 IL4
4 fraser syndrome 1 10.8
5 bosma arhinia microphthalmia syndrome 10.8
6 physical urticaria 10.4 MS4A2 TRPV1
7 loeffler endocarditis 10.4 IL5 RNASE3
8 parasitic ichthyosporea infectious disease 10.4 IL4 RHNO1
9 respiratory syncytial virus infectious disease 10.4 IL13 IL5
10 rhinosporidiosis 10.4 IL4 RHNO1
11 cytokine deficiency 10.4 IL13 IL5
12 pemphigoid gestationis 10.4 CCL11 IL5
13 leiomyoma cutis 10.3 TAC1 TRPV1
14 prurigo nodularis 10.3 RNASE3 TAC1
15 eye lymphoma 10.3 IL10 TLR9
16 cephalosporin allergy 10.3 IL10 IL5
17 hyperlucent lung 10.3 IL10 IL4
18 mikulicz disease 10.3 IL5 PTGDR2
19 ascaridiasis 10.3 IL10 IL13
20 bagassosis 10.3 CXCL8 IL5
21 sezary's disease 10.3 IL4 IL5 TLR9
22 autoimmune myocarditis 10.3 IL4 TNF
23 tracheitis 10.3 RHNO1 TNF
24 bullous pemphigoid 10.3 CCL11 IL5 RNASE3
25 neurosyphilis 10.3 CXCL8 IL10
26 acute transverse myelitis 10.3 CXCL8 IL10
27 pouchitis 10.3 CXCL8 IL10
28 atopic keratoconjunctivitis 10.3 IL4 IL5 RNASE3
29 stomach disease 10.3 CXCL8 TLR9 TRPV1
30 transient hypogammaglobulinemia 10.3 IL10 TNF
31 bacterial pneumonia 10.3 CXCL8 TLR9 TRPV1
32 paragonimiasis 10.3 IL13 IL5 RNASE3
33 intrinsic asthma 10.3 IL4 IL5 RNASE3
34 microscopic polyangiitis 10.3 IL10 TNF
35 multifocal choroiditis 10.3 IL10 TNF
36 blepharoconjunctivitis 10.3 CCL11 IL4 RNASE3
37 arteries, anomalies of 10.3 TLR9 TNF TRPV1
38 acquired metabolic disease 10.3 TLR9 TNF TRPV1
39 dry eye syndrome 10.3 TLR9 TNF TRPV1
40 urinary system disease 10.3 TLR9 TNF TRPV1
41 glucose metabolism disease 10.2 TLR9 TNF TRPV1
42 exudative glomerulonephritis 10.2 CXCL8 TNF
43 streptococcal toxic-shock syndrome 10.2 CXCL8 TNF
44 lichen planus 10.2 IL4 TLR9 TNF
45 chronic eosinophilic pneumonia 10.2 CCL11 IL5 RNASE3
46 intestinal schistosomiasis 10.2 IL13 IL4 IL5
47 maxillary sinusitis 10.2 MUC5B RHNO1 RNASE3
48 chronic tic disorder 10.2 IL13 IL4 IL5
49 strongyloidiasis 10.2 CCL11 IL13 IL5
50 cough variant asthma 10.2 IL4 IL5 RNASE3 TRPV1

Graphical network of the top 20 diseases related to Nose Disease:



Diseases related to Nose Disease

Symptoms & Phenotypes for Nose Disease

UMLS symptoms related to Nose Disease:


dyspnea, apnea, rhinorrhea

MGI Mouse Phenotypes related to Nose Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.07 CCL11 CHD7 HRH1 IL10 IL13 IL4
2 homeostasis/metabolism MP:0005376 9.97 CHD7 HRH1 IL10 IL13 IL4 IL5
3 digestive/alimentary MP:0005381 9.92 CHD7 IL10 IL13 IL4 IL5 TLR9
4 immune system MP:0005387 9.83 CCL11 CHD7 CYSLTR1 HRH1 IL10 IL13
5 respiratory system MP:0005388 9.32 CCL11 CHD7 CYSLTR1 IL10 IL13 IL4

Drugs & Therapeutics for Nose Disease

Drugs for Nose Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 518)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 26787-78-0 33613
2 Strawberry Approved Phase 4,Phase 3
3
Cefditoren Approved, Investigational Phase 4 117467-28-4, 104145-95-1 9571074 9870843
4
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 124-94-7 31307
5
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-45-6, 75614-87-8 774
6
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 90-82-4 7028
7
Azelastine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 58581-89-8 2267
8
mometasone furoate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 83919-23-7
9
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 83-43-2 6741
10
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3,Phase 2 2921-57-5
11
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 299-42-3 9294
12
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3,Phase 2 302-25-0
13
Xylometazoline Approved, Investigational Phase 4,Not Applicable 526-36-3 5709
14
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-24-8 5755
15
Fluticasone Approved, Experimental Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 90566-53-3 62924
16
Capsaicin Approved Phase 4,Phase 2,Phase 1 404-86-4 1548943
17
Lansoprazole Approved, Investigational Phase 4,Not Applicable 103577-45-3 3883
18
Dexlansoprazole Approved, Investigational Phase 4,Not Applicable 103577-45-3, 138530-94-6 9578005
19
Levocetirizine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 130018-77-8 1549000
20
Cetirizine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 83881-51-0 2678
21
Montelukast Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 158966-92-8 5281040
22
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
23
Remifentanil Approved Phase 4 132875-61-7 60815
24
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
25
Metoprolol Approved, Investigational Phase 4 37350-58-6, 51384-51-1 4171
26
Nitric Oxide Approved Phase 4,Phase 1,Phase 2,Not Applicable 10102-43-9 145068
27
Budesonide Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51333-22-3 63006 5281004
28
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 137-58-6 3676
29
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable 53-03-2 5865
30
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 51-43-4 5816
31
Racepinephrine Approved Phase 4,Phase 3,Phase 2,Not Applicable 329-65-7 838
32
Loratadine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 79794-75-5 3957
33
Desloratadine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 100643-71-8 124087
34
Oxymetazoline Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1491-59-4 4636
35
Phenylephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 59-42-7 6041
36
Betamethasone Approved, Vet_approved Phase 4,Phase 3 378-44-9 9782
37
Omalizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 242138-07-4
38
Bevacizumab Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 216974-75-3
39
Ketamine Approved, Vet_approved Phase 4,Not Applicable 6740-88-1 3821
40
Formaldehyde Approved, Vet_approved Phase 4,Not Applicable 50-00-0 712
41
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2,Not Applicable 1197-18-8 5526
42
Ethanol Approved Phase 4,Phase 2,Phase 1,Not Applicable 64-17-5 702
43
Azithromycin Approved Phase 4,Phase 3,Phase 2,Not Applicable 83905-01-5 55185 447043
44
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2 564-25-0 54671203
45
Dopamine Approved Phase 4,Phase 3,Phase 2 51-61-6, 62-31-7 681
46
Cocaine Approved, Illicit Phase 4 50-36-2 5760 446220
47
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
48
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
49
Norgestimate Approved, Investigational Phase 4,Phase 3 35189-28-7 6540478
50 Estradiol valerate Approved, Investigational, Vet_approved Phase 4,Phase 3 979-32-8

Interventional clinical trials:

(show top 50) (show all 1415)
# Name Status NCT ID Phase Drugs
1 Middle Meatal Bacteriology During Acute Respiratory Infection in Children Unknown status NCT00545961 Phase 4 placebo;amoxicillin clavulanate acid
2 Study of Cefditoren Pivoxil in Treatment of Childhood With Acute Rhinosinusitis Unknown status NCT01553006 Phase 4 cefditoren pivoxil
3 A Prospective Randomised Controlled Trial of Management of Recurrent Nosebleeds in Children Unknown status NCT00390663 Phase 4
4 The Effectiveness of Nasal Corticosteroids Versus Placebo in Nasal Obstruction in Patients With Nasal Septal Deviation Unknown status NCT02877485 Phase 4 Triamcinolone Acetonide;Ayr saline nasal mist
5 4"S" - Seasonal Symptoms Suppression Study Unknown status NCT02557269 Phase 4 Xylometazoline - intranasal application;Azelastine - intranasal application;Mometasone furoate - intranasal application;Hydroxyl-propyl-methyl cellulose powder - intranasal application;Bilastine 20 mg;Prednisolone 5 mg
6 Evaluating Factors Involved in Dymista's Superior Clinical Efficacy to Fluticasone Propionate in the Treatment of Seasonal Allergic Rhinitis Unknown status NCT02402465 Phase 4 Placebo;Fluticasone propionate;Fluticasone/Azelastine nasal spray
7 Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic Rhinitis Unknown status NCT02288156 Phase 4 Capsaicin;placebo
8 The Relationship Between Gastroesophageal Reflux and Pediatric Rhinitis: Significance of Pale/Blue Colored Turbinate Unknown status NCT02278081 Phase 4 lansoprazole;placebo
9 AZELASTINE/FLUTICASONE (AZE/FLU) Nasal Spray on Symptom Control, Nasal Mediators and Nasal Hyperresponsiveness in Allergic Rhinitis (AR) Unknown status NCT02238353 Phase 4 azelastine + fluticasone;Placebo
10 Immunological Mechanisms of Oralair® in Patients With Seasonal Allergic Rhinitis Unknown status NCT02014623 Phase 4 Control
11 Efficacy of Allergen Immunotherapy for Allergic Rhinitis in Thais Unknown status NCT01115595 Phase 4
12 Cosalin® Monotherapy Versus Cosalin® and Xarlin® Combination Therapy Unknown status NCT01062139 Phase 4 Xarlin (Levocetirizine);Cosalin (Petasites hybridus CO2 extract)
13 Comparative Study of Sinol and Sinol-M in Patients With Congestion Due to Allergic Rhinitis Unknown status NCT00825656 Phase 4 Sinol or Sinol-M nasal spray
14 Singulair Use in Non-Allergic Rhinitis Eosinophil Syndrome (NARES) Unknown status NCT00406094 Phase 4 montelukast;placebo
15 Remifentanil and Controlled Hypotension for Functional Endoscopic Sinus Surgery: Comparison With Tramadol and Metoprolol Unknown status NCT02484859 Phase 4 Remifentanil;Tramadol;Metoprolol
16 POLlinosis and Exhaled Breath Temperature Unknown status NCT01785394 Phase 4 5 grass allergen extract
17 Comparison of the Effect of Montelukast and Cetirizine on Allergic Inflammation in Children With Allergic Rhinitis Unknown status NCT00488176 Phase 4 montelukast;cetirizine;montelukast and cetirizine;placebo
18 Comparison of Daily Mometasone Furoate Nasal Spray Alone Versus a Combination With Montelukast for Treatment of Chronic Rhinosinusitis With Asthma After Functional Endoscopic Sinus Surgery Unknown status NCT02110654 Phase 4 Montelukast;mometasone furoate nasal spray
19 Assessment of Sublingual Immunotherapy in Children Allergic to House Dust Mites Unknown status NCT01052610 Phase 4 sublingual house dust mites allergen extract;placebo in sublingual applicator
20 The Efficacy and Safety of Hyeonggaeyeongyo-tang for Chronic Rhinitis According to Pattern Identification in Korean Medicine Completed NCT02477293 Phase 4 Hyeonggaeyeongyo-tang
21 The Optimal Head Position for Distributing Topical Nasal Medication Using the Mucosal Atomization Device Completed NCT02079792 Phase 4
22 Fluticasone and Salmeterol in Allergic Rhinitis Completed NCT01388595 Phase 4 FLUTICASONE PROPRIONATE;Salmeterol;PLACEBO
23 Fluticasone Furoate Treatment of Daytime Somnolence and Cognitive Performance in Seasonal Allergic Rhinitis Completed NCT00997620 Phase 4 Fluticasone furoate Nasal Spray 110 mcg;Placebo
24 Effect of Ketamine Addition to Lidocaine in Rhinoplasty Completed NCT01827020 Phase 4 Lidocaine 2 %;Ketamine plus Lidocaine;Saline
25 Evaluation Of Cloumella Strut Effect In Tip Rotation Completed NCT00467714 Phase 4
26 Mechanisms of Capsaicin Treatment in Idiopathic Rhinitis Patients and Controls Completed NCT01862523 Phase 4
27 Neuro-immunological Analysis of Idiopathic Rhinitis Patients and Controls Treated With Capsaicin. Completed NCT01223820 Phase 4 Capsaicin
28 Safety and Efficacy of Olopatadine 0.6% and Azelastine 137 Mcg in Vasomotor Rhinitis Completed NCT00979615 Phase 4 Olopatadine HCL (Patanase) Nasal Spray, 0.6%;Azelastine HCl (Astelin) Nasal Spray, 137 mcg
29 Comparing Effectiveness of Merocel and Packing With Tranexamic Acid in the Management of Anterior Epistaxis Completed NCT03360045 Phase 4 Tranexamic Acid;Normal saline
30 The PIO II Study: In-office Post-op Placement of a Steroid-eluting Sinus Implant Completed NCT02668302 Phase 4
31 Clinical Trial of the Treatment of Acute Sinusitis With Standard-dose Versus High-dose Amoxicillin/Clavulanate Completed NCT02340000 Phase 4 standard dose amoxicillin/clavulanate;high dose amoxicillin/clavulanate
32 Azithromycin for Patients With Chronic Rhinosinusitis Failing Medical and Surgical Therapy Completed NCT02307825 Phase 4 Azithromycin;Placebo
33 Efficacy and Safety of Sinusitis Hevert SL Tablets Compared to Placebo in Adult Patients With Acute, Uncomplicated Rhinosinusitis Completed NCT02296814 Phase 4 Sinusitis Hevert SL Tablet;Placebo for Sinusitis Hevert SL Tablet
34 Prophylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Controlled Trial Completed NCT01919411 Phase 4 Amoxicillin-Potassium Clavulanate;Placebo
35 Medical Polypectomy and Predictors of Response Completed NCT00788749 Phase 4 Prednisolone;Placebo
36 Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis Completed NCT01825408 Phase 4 Doxycycline;Azithromycin;Augmentin
37 Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery Completed NCT01706952 Phase 4 Cocaine;Adrenaline
38 Saline Irrigation After Surgery in Patients With Chronic Sinusitis Completed NCT01575223 Phase 4
39 Randomized Controlled Trial to Evaluate of Dexmedetomidine for the Effect on Operative Visibility in Patients Undergoing Endoscopic Sinus Surgery Completed NCT01569048 Phase 4 Propofol and dexmedetomidine;propofol and remifentanil
40 Medicated Punctured-Glove-Finger Spacer Study Completed NCT01420471 Phase 4 Triamcinolone
41 Systemic Methylprednisolone in Chronic Rhinosinusitis Completed NCT01205984 Phase 4 methylprednisolone
42 Sinuclean's Treatment Of Sinusitis' Symptoms Completed NCT00747747 Phase 4
43 Trial to Evaluate Time to Symptom Relief and Elimination of Infecting Bacteria in Treating Sinusitis With Avelox Completed NCT00668304 Phase 4 Avelox (Moxifloxacin, BAY12-8039)
44 Study of the Safety and Efficacy of Cefdinir and Levofloxacin for the Treatment of Subjects With Acute Bacterial Sinusitis Completed NCT00645073 Phase 4 cefdinir (Omnicef);levofloxacin
45 Study to Evaluate Safety and Effectiveness of AdvaCoat Sinus Gel Completed NCT00554190 Phase 4
46 Use of Probiotics as Adjunctive Treatment for Chronic Rhinosinusitis Completed NCT00396162 Phase 4 probiotic containing L.rhamnosus R0011 strain
47 Treatment of Acute Sinusitis Completed NCT00377403 Phase 4 Acetaminophen;Amoxicillin;Dextromethorphan hydrobromide with guaifenesin;Guaifenesin;Pseudoephedrine Sustained Action;Saline spray (0.65%)
48 Zmax Compared to Augmentin in Sinusitis Completed NCT00367120 Phase 4 Azithromycin Extended Release;Amoxicillin/Clavulanate
49 Hemostatic Matrix in Endoscopic Sinus Surgery Completed NCT00242437 Phase 4
50 CHOOSE : Telithromycin, Acute Bacterial Sinusitis Completed NCT00174694 Phase 4 Telithromycin

Search NIH Clinical Center for Nose Disease

Cochrane evidence based reviews: nose diseases

Genetic Tests for Nose Disease

Genetic tests related to Nose Disease:

# Genetic test Affiliating Genes
1 Abnormality of the Nose 29

Anatomical Context for Nose Disease

MalaCards organs/tissues related to Nose Disease:

41
Bone, Lung, Skin, Salivary Gland

Publications for Nose Disease

Articles related to Nose Disease:

# Title Authors Year
1
Hippocrates the otolaryngologist: an epidemiological analysis of ear-throat-nose diseases in the Corpus Hippocraticum. ( 29385936 )
2018
2
Blue nose disease in the horse. ( 18124494 )
1949

Variations for Nose Disease

Expression for Nose Disease

Search GEO for disease gene expression data for Nose Disease.

Pathways for Nose Disease

Pathways related to Nose Disease according to GeneCards Suite gene sharing:

(show all 37)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14 CCL11 CXCL8 IL10 IL13 IL4 IL5
2
Show member pathways
13.38 CCL11 CXCL8 IL10 IL13 IL4 IL5
3
Show member pathways
13.31 CCL11 CXCL8 IL10 IL13 IL4 IL5
4
Show member pathways
13.25 CCL11 CXCL8 IL10 IL13 IL4 IL5
5
Show member pathways
12.85 CCL11 CXCL8 IL10 IL13 IL4 IL5
6
Show member pathways
12.74 CXCL8 IL13 IL4 TLR9 TNF
7
Show member pathways
12.57 IL10 IL13 IL4 IL5 TNF
8
Show member pathways
12.55 IL13 IL4 IL5 MS4A2 TNF
9
Show member pathways
12.37 IL10 IL4 IL5 TNF
10
Show member pathways
12.37 IL10 IL13 IL4 IL5 TSLP
11
Show member pathways
12.27 CXCL8 IL10 IL13 IL4 IL5 TNF
12
Show member pathways
12.24 CCL11 CXCL8 IL13 IL4 IL5 MUC5B
13
Show member pathways
12.18 CCL11 CXCL8 IL4 TLR9 TNF
14 12.17 CXCL8 IL10 IL13 TAC1 TNF
15
Show member pathways
12.08 CCL11 CXCL8 IL10 IL13 IL4 IL5
16 11.99 IL10 IL4 IL5 PTGDR2 TNF
17 11.94 CCL11 CXCL8 IL10 IL13 IL4 TNF
18 11.84 IL4 IL5 TNF
19 11.83 CXCL8 IL10 TNF
20 11.82 CXCL8 IL13 IL4 IL5
21
Show member pathways
11.78 CXCL8 IL4 IL5 TNF
22 11.74 CCL11 IL10 IL13 IL4 TNF
23 11.71 CXCL8 IL10 TNF
24 11.69 IL10 TLR9 TNF
25 11.68 CCL11 IL10 IL4 IL5
26 11.57 CXCL8 IL10 IL13 IL4 TNF
27 11.53 CXCL8 IL10 TLR9 TNF
28 11.49 CCL11 CXCL8 TSLP
29 11.49 CCL11 IL10 IL13 IL4 IL5
30 11.4 IL10 IL13 IL4 IL5 PTGDR2 TNF
31 11.34 IL10 TLR9 TNF
32 11.23 IL10 IL13 IL4 IL5
33 11.16 IL13 IL4 IL5 TNF TSLP
34 11.1 CCL11 CXCL8 IL10 IL13 IL4 IL5
35 11.02 IL10 IL13 IL4 IL5 TNF
36 10.99 CCL11 CXCL8 IL10 IL13 IL4 IL5
37 10.97 CCL11 CXCL8 IL13 IL4 IL5 MUC5B

GO Terms for Nose Disease

Cellular components related to Nose Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.73 CCL11 CXCL8 IL10 IL13 IL4 IL5
2 extracellular space GO:0005615 9.36 CCL11 CXCL8 IL10 IL13 IL4 IL5

Biological processes related to Nose Disease according to GeneCards Suite gene sharing:

(show all 31)
# Name GO ID Score Top Affiliating Genes
1 defense response to bacterium GO:0042742 9.93 IL10 RNASE3 TLR9 TNF
2 chemotaxis GO:0006935 9.85 CCL11 CXCL8 CYSLTR1 PTGDR2
3 neuropeptide signaling pathway GO:0007218 9.83 CYSLTR1 PTGDR2 TAC1
4 positive regulation of inflammatory response GO:0050729 9.8 TLR9 TNF TSLP
5 cytokine-mediated signaling pathway GO:0019221 9.8 CCL11 CXCL8 IL10 IL13 IL4 IL5
6 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.78 IL13 IL4 TSLP
7 positive regulation of interleukin-6 production GO:0032755 9.76 TLR9 TNF TSLP
8 regulation of signaling receptor activity GO:0010469 9.76 CCL11 CXCL8 IL10 IL13 IL4 IL5
9 negative regulation of endothelial cell apoptotic process GO:2000352 9.69 IL10 IL13 IL4
10 negative regulation of growth of symbiont in host GO:0044130 9.65 IL10 TNF
11 immune response GO:0006955 9.65 CCL11 CXCL8 IL10 IL13 IL4 IL5
12 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.64 IL10 TNF
13 positive regulation of podosome assembly GO:0071803 9.63 IL5 TNF
14 negative regulation of interleukin-6 production GO:0032715 9.63 IL10 TLR9 TNF
15 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.62 TLR9 TNF
16 positive regulation of B cell proliferation GO:0030890 9.62 IL13 IL4 IL5 TLR9
17 positive regulation of interleukin-13 production GO:0032736 9.61 IL4 TSLP
18 positive regulation of chemokine production GO:0032722 9.61 TLR9 TNF TSLP
19 endothelial cell apoptotic process GO:0072577 9.6 IL10 TNF
20 positive regulation of immunoglobulin production GO:0002639 9.59 IL13 TLR9
21 negative regulation of interleukin-8 production GO:0032717 9.58 IL10 TLR9
22 microglial cell activation GO:0001774 9.58 IL13 TNF TRPV1
23 positive regulation of MHC class II biosynthetic process GO:0045348 9.57 IL10 IL4
24 negative regulation of cytokine secretion involved in immune response GO:0002740 9.56 IL10 TNF
25 regulation of isotype switching GO:0045191 9.54 IL10 IL4
26 response to molecule of bacterial origin GO:0002237 9.54 CXCL8 IL10 TLR9
27 type 2 immune response GO:0042092 9.52 IL10 IL4
28 negative regulation of complement-dependent cytotoxicity GO:1903660 9.49 IL13 IL4
29 receptor biosynthetic process GO:0032800 9.48 IL10 TNF
30 inflammatory response GO:0006954 9.36 CCL11 CXCL8 HRH1 IL10 IL13 IL5
31 signal transduction GO:0007165 10.24 CCL11 CXCL8 CYSLTR1 HRH1 MS4A2 PDCL

Molecular functions related to Nose Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.23 CCL11 CXCL8 IL10 IL13 IL4 IL5

Sources for Nose Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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