MCID: NSD001
MIFTS: 50

Nose Disease

Categories: Respiratory diseases, Smell/Taste diseases

Aliases & Classifications for Nose Disease

MalaCards integrated aliases for Nose Disease:

Name: Nose Disease 12 15
Nose Diseases 44 73
Abnormality of the Nose 29
Disorder of the Nose 12
Nasal Disorder 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2825
MeSH 44 D009668
SNOMED-CT 68 89488007
ICD10 33 J33.9
UMLS 73 C0028432

Summaries for Nose Disease

MalaCards based summary : Nose Disease, also known as nose diseases, is related to vasomotor rhinitis and allergic rhinitis, and has symptoms including apnea, dyspnea and rhinorrhea. An important gene associated with Nose Disease is TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. The drugs Amoxicillin and Cefditoren have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and lung, and related phenotypes are Increased transferrin (TF) endocytosis and hematopoietic system

Wikipedia : 76 The human nose is the protruding part of the face that bears the nostrils. The shape of the nose is... more...

Related Diseases for Nose Disease

Diseases related to Nose Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 190)
# Related Disease Score Top Affiliating Genes
1 vasomotor rhinitis 30.5 RNASE3 TAC1 TLR9
2 allergic rhinitis 27.6 CCL11 CXCL8 HRH1 IL10 IL13 IL4
3 rhinitis 27.5 CCL11 CXCL8 CYSLTR1 HRH1 IL13 IL4
4 cytokine deficiency 11.0 IL13 IL5
5 loeffler endocarditis 10.9 IL5 RNASE3
6 intrinsic asthma 10.9 IL4 IL5 RNASE3
7 atopic keratoconjunctivitis 10.9 IL4 IL5 RNASE3
8 pemphigoid gestationis 10.9 CCL11 IL5
9 angioimmunoblastic lymphadenopathy with dysproteinemia 10.9 IL13 IL5
10 paragonimiasis 10.9 IL13 IL5 RNASE3
11 blepharoconjunctivitis 10.9 CCL11 IL4 RNASE3
12 chronic interstitial cystitis 10.9 CD79A RNASE3
13 eosinophilic gastroenteritis 10.8 CCL11 IL5 RNASE3
14 chronic eosinophilic pneumonia 10.8 CCL11 IL5 RNASE3
15 intestinal schistosomiasis 10.8 IL13 IL4 IL5
16 chronic tic disorder 10.8 IL13 IL4 IL5
17 enterobiasis 10.8 IL13 IL4 IL5
18 tropical endomyocardial fibrosis 10.8 IL10 IL4
19 ascaris lumbricoides infection 10.8 IL13 IL5 TSLP
20 night blindness, congenital stationary, type 1a 10.8 CCL11 IL13 IL5
21 prurigo nodularis 10.8 RNASE3 TAC1
22 maxillary sinusitis 10.8 CD79A RHNO1 RNASE3
23 sezary's disease 10.8 IL4 IL5 TLR9
24 cough variant asthma 10.8 IL4 IL5 RNASE3 TRPV1
25 encapsulated thymoma 10.7 CD79A MUC5B
26 respiratory syncytial virus infectious disease 10.7 IL13 IL5
27 somatoform disorder 10.7 IL4 TAC1 TRPV1
28 lichen disease 10.7 CD79A IL4 TLR9
29 neuroschistosomiasis 10.7 CD79A TAC1
30 parasitic ichthyosporea infectious disease 10.7 CD79A IL4 RHNO1
31 rhinosporidiosis 10.7 CD79A IL4 RHNO1
32 primary amebic meningoencephalitis 10.7 CD79A IL4 IL5
33 lacrimal apparatus disease 10.7 IL10 TLR9 TRPV1
34 ocular cicatricial pemphigoid 10.7 CD79A IL4 RNASE3
35 hyperlucent lung 10.7 IL10 IL4
36 anisakiasis 10.7 CD79A RNASE3
37 inflammatory bowel disease 4 10.7 IL13 IL4 IL5 RNASE3
38 latex allergy 10.7 IL13 IL4 IL5 RNASE3
39 urinary schistosomiasis 10.7 IL13 IL4 IL5 RNASE3
40 genital herpes 10.7 IL10 IL4 TLR9
41 churg-strauss syndrome 10.7 IL10 IL5 RNASE3
42 eye lymphoma 10.7 IL10 TLR9
43 bagassosis 10.7 CXCL8 IL5
44 extrinsic cardiomyopathy 10.7 IL10 IL4 TLR9
45 status asthmaticus 10.7 CXCL8 IL5 RNASE3
46 ascaridiasis 10.7 IL10 IL13
47 beta-lactam allergy 10.7 IL10 IL13 IL4
48 exudative glomerulonephritis 10.7 CD79A CXCL8
49 endomyocardial fibrosis 10.6 IL10 IL4
50 dermatitis herpetiformis 10.6 CCL11 CD79A IL4

Graphical network of the top 20 diseases related to Nose Disease:



Diseases related to Nose Disease

Symptoms & Phenotypes for Nose Disease

UMLS symptoms related to Nose Disease:


apnea, dyspnea, rhinorrhea

GenomeRNAi Phenotypes related to Nose Disease according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased transferrin (TF) endocytosis GR00363-A 9.4 PDCL PTGDR2 TAC1 TLR9 CD79A CXCL8

MGI Mouse Phenotypes related to Nose Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.07 MS4A2 MUC5B HRH1 PTGDR2 IL10 TLR9
2 homeostasis/metabolism MP:0005376 9.97 CHD7 MUC5B PDCL HRH1 PTGDR2 IL10
3 digestive/alimentary MP:0005381 9.87 TSLP CHD7 IL10 TLR9 IL13 IL4
4 immune system MP:0005387 9.83 MUC5B CYSLTR1 HRH1 PTGDR2 IL10 TLR9
5 respiratory system MP:0005388 9.28 CHD7 MUC5B CYSLTR1 IL10 IL13 TSLP

Drugs & Therapeutics for Nose Disease

Drugs for Nose Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 493)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 26787-78-0 33613
2
Cefditoren Approved, Investigational Phase 4 117467-28-4, 104145-95-1 9571074 9870843
3
Azelastine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 58581-89-8 2267
4
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 299-42-3 9294
5
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 75614-87-8, 51-45-6 774
6
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 83-43-2 6741
7
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-24-8 5755
8
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 90-82-4 7028
9
Xylometazoline Approved, Investigational Phase 4,Not Applicable 526-36-3 5709
10
Fluticasone Approved, Experimental, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 90566-53-3 62924
11
Capsaicin Approved Phase 4,Phase 2,Phase 1 404-86-4 1548943
12
Dexlansoprazole Approved, Investigational Phase 4,Not Applicable 138530-94-6, 103577-45-3 9578005
13
Lansoprazole Approved, Investigational Phase 4,Not Applicable 103577-45-3 3883
14
Cetirizine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 83881-51-0 2678
15
Levocetirizine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 130018-77-8 1549000
16
Montelukast Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 158966-92-8 5281040
17
Metoprolol Approved, Investigational Phase 4 37350-58-6, 51384-51-1 4171
18
Remifentanil Approved Phase 4 132875-61-7 60815
19
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
20
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
21
Nitric Oxide Approved Phase 4,Phase 1,Phase 2,Not Applicable 10102-43-9 145068 160954
22
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 137-58-6 3676
23
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Not Applicable 53-03-2 5865
24
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 51-43-4 5816
25
Racepinephrine Approved Phase 4,Phase 3,Phase 2,Not Applicable 329-65-7 838
26
Loratadine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 79794-75-5 3957
27
Desloratadine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 100643-71-8 124087
28
Oxymetazoline Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1491-59-4 4636
29
Phenylephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 59-42-7 6041
30
Betamethasone Approved, Vet_approved Phase 4,Phase 3 378-44-9 9782
31
Omalizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 242138-07-4
32
Bevacizumab Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 216974-75-3
33
Menthol Approved Phase 4,Phase 2,Not Applicable 2216-51-5 16666
34
Budesonide Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 51333-22-3 63006 5281004
35
Ketamine Approved, Vet_approved Phase 4,Not Applicable 6740-88-1 3821
36
Azithromycin Approved Phase 4,Phase 3,Phase 2,Not Applicable 83905-01-5 55185 447043
37
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2 564-25-0 54671203
38
Cocaine Approved, Illicit Phase 4 50-36-2 5760 446220
39
Dopamine Approved Phase 4,Phase 2 51-61-6, 62-31-7 681
40
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
41
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
42
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 124-94-7 31307
43
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3 50-28-2 5757
44 Estradiol valerate Approved, Investigational, Vet_approved Phase 4,Phase 3 979-32-8
45
Ethinyl Estradiol Approved Phase 4,Phase 3 57-63-6 5991
46
Moxifloxacin Approved, Investigational Phase 4,Phase 3 354812-41-2, 151096-09-2 152946
47
Norgestimate Approved, Investigational Phase 4,Phase 3 35189-28-7 6540478
48
Polyestradiol phosphate Approved Phase 4,Phase 3 28014-46-2
49
Cefdinir Approved Phase 4 91832-40-5 6915944
50
Levofloxacin Approved, Investigational Phase 4,Phase 3 100986-85-4 149096

Interventional clinical trials:

(show top 50) (show all 1354)
# Name Status NCT ID Phase Drugs
1 Middle Meatal Bacteriology During Acute Respiratory Infection in Children Unknown status NCT00545961 Phase 4 placebo;amoxicillin clavulanate acid
2 The Efficacy and Complication of Gentamicin Nasal Irrigation in Chronic Rhinosinusitis and Recurrent Sinusitis Unknown status NCT02582099 Phase 4 Gentamicin nasal irrigation;Normal saline nasal irrigation
3 Study of Cefditoren Pivoxil in Treatment of Childhood With Acute Rhinosinusitis Unknown status NCT01553006 Phase 4 cefditoren pivoxil
4 A Prospective Randomised Controlled Trial of Management of Recurrent Nosebleeds in Children Unknown status NCT00390663 Phase 4
5 4"S" - Seasonal Symptoms Suppression Study Unknown status NCT02557269 Phase 4 Xylometazoline - intranasal application;Azelastine - intranasal application;Mometasone furoate - intranasal application;Hydroxyl-propyl-methyl cellulose powder - intranasal application;Bilastine 20 mg;Prednisolone 5 mg
6 Evaluating Factors Involved in Dymista's Superior Clinical Efficacy to Fluticasone Propionate in the Treatment of Seasonal Allergic Rhinitis Unknown status NCT02402465 Phase 4 Placebo;Fluticasone propionate;Fluticasone/Azelastine nasal spray
7 Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic Rhinitis Unknown status NCT02288156 Phase 4 Capsaicin;placebo
8 The Relationship Between Gastroesophageal Reflux and Pediatric Rhinitis: Significance of Pale/Blue Colored Turbinate Unknown status NCT02278081 Phase 4 lansoprazole;placebo
9 AZELASTINE/FLUTICASONE (AZE/FLU) Nasal Spray on Symptom Control, Nasal Mediators and Nasal Hyperresponsiveness in Allergic Rhinitis (AR) Unknown status NCT02238353 Phase 4 azelastine + fluticasone;Placebo
10 Immunological Mechanisms of Oralair® in Patients With Seasonal Allergic Rhinitis Unknown status NCT02014623 Phase 4 Control
11 Efficacy of Allergen Immunotherapy for Allergic Rhinitis in Thais Unknown status NCT01115595 Phase 4
12 Cosalin® Monotherapy Versus Cosalin® and Xarlin® Combination Therapy Unknown status NCT01062139 Phase 4 Xarlin (Levocetirizine);Cosalin (Petasites hybridus CO2 extract)
13 Comparative Study of Sinol and Sinol-M in Patients With Congestion Due to Allergic Rhinitis Unknown status NCT00825656 Phase 4 Sinol or Sinol-M nasal spray
14 Singulair Use in Non-Allergic Rhinitis Eosinophil Syndrome (NARES) Unknown status NCT00406094 Phase 4 montelukast;placebo
15 Remifentanil and Controlled Hypotension for Functional Endoscopic Sinus Surgery: Comparison With Tramadol and Metoprolol Unknown status NCT02484859 Phase 4 Remifentanil;Tramadol;Metoprolol
16 POLlinosis and Exhaled Breath Temperature Unknown status NCT01785394 Phase 4 5 grass allergen extract
17 Comparison of the Effect of Montelukast and Cetirizine on Allergic Inflammation in Children With Allergic Rhinitis Unknown status NCT00488176 Phase 4 montelukast;cetirizine;montelukast and cetirizine;placebo
18 Comparison of Daily Mometasone Furoate Nasal Spray Alone Versus a Combination With Montelukast for Treatment of Chronic Rhinosinusitis With Asthma After Functional Endoscopic Sinus Surgery Unknown status NCT02110654 Phase 4 Montelukast;mometasone furoate nasal spray
19 Assessment of Sublingual Immunotherapy in Children Allergic to House Dust Mites Unknown status NCT01052610 Phase 4 sublingual house dust mites allergen extract;placebo in sublingual applicator
20 The Efficacy and Safety of Hyeonggaeyeongyo-tang for Chronic Rhinitis According to Pattern Identification in Korean Medicine Completed NCT02477293 Phase 4 Hyeonggaeyeongyo-tang
21 The Optimal Head Position for Distributing Topical Nasal Medication Using the Mucosal Atomization Device Completed NCT02079792 Phase 4
22 Fluticasone and Salmeterol in Allergic Rhinitis Completed NCT01388595 Phase 4 FLUTICASONE PROPRIONATE;Salmeterol;PLACEBO
23 Fluticasone Furoate Treatment of Daytime Somnolence and Cognitive Performance in Seasonal Allergic Rhinitis Completed NCT00997620 Phase 4 Fluticasone furoate Nasal Spray 110 mcg;Placebo
24 Effect of Ketamine Addition to Lidocaine in Rhinoplasty Completed NCT01827020 Phase 4 Lidocaine 2 %;Ketamine plus Lidocaine;Saline
25 Evaluation Of Cloumella Strut Effect In Tip Rotation Completed NCT00467714 Phase 4
26 Mechanisms of Capsaicin Treatment in Idiopathic Rhinitis Patients and Controls Completed NCT01862523 Phase 4
27 Neuro-immunological Analysis of Idiopathic Rhinitis Patients and Controls Treated With Capsaicin. Completed NCT01223820 Phase 4 Capsaicin
28 Safety and Efficacy of Olopatadine 0.6% and Azelastine 137 Mcg in Vasomotor Rhinitis Completed NCT00979615 Phase 4 Olopatadine HCL (Patanase) Nasal Spray, 0.6%;Azelastine HCl (Astelin) Nasal Spray, 137 mcg
29 The PIO II Study of In-office Placement of a Steroid-eluting Sinus Implant Completed NCT02668302 Phase 4
30 Clinical Trial of the Treatment of Acute Sinusitis With Standard-dose Versus High-dose Amoxicillin/Clavulanate Completed NCT02340000 Phase 4 standard dose amoxicillin/clavulanate;high dose amoxicillin/clavulanate
31 Azithromycin for Patients With Chronic Rhinosinusitis Failing Medical and Surgical Therapy Completed NCT02307825 Phase 4 Azithromycin;Placebo
32 Efficacy and Safety of Sinusitis Hevert SL Tablets Compared to Placebo in Adult Patients With Acute, Uncomplicated Rhinosinusitis Completed NCT02296814 Phase 4 Sinusitis Hevert SL Tablet;Placebo for Sinusitis Hevert SL Tablet
33 Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis Completed NCT01825408 Phase 4 Doxycycline;Azithromycin;Augmentin
34 Medical Polypectomy and Predictors of Response Completed NCT00788749 Phase 4 Prednisolone;Placebo
35 Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery Completed NCT01706952 Phase 4 Cocaine;Adrenaline
36 Saline Irrigation After Surgery in Patients With Chronic Sinusitis Completed NCT01575223 Phase 4
37 Randomized Controlled Trial to Evaluate of Dexmedetomidine for the Effect on Operative Visibility in Patients Undergoing Endoscopic Sinus Surgery Completed NCT01569048 Phase 4 Propofol and dexmedetomidine;propofol and remifentanil
38 Medicated Punctured-Glove-Finger Spacer Study Completed NCT01420471 Phase 4 Triamcinolone
39 Systemic Methylprednisolone in Chronic Rhinosinusitis Completed NCT01205984 Phase 4 methylprednisolone
40 Sinuclean's Treatment Of Sinusitis' Symptoms Completed NCT00747747 Phase 4
41 Trial to Evaluate Time to Symptom Relief and Elimination of Infecting Bacteria in Treating Sinusitis With Avelox Completed NCT00668304 Phase 4 Avelox (Moxifloxacin, BAY12-8039)
42 Study of the Safety and Efficacy of Cefdinir and Levofloxacin for the Treatment of Subjects With Acute Bacterial Sinusitis Completed NCT00645073 Phase 4 cefdinir (Omnicef);levofloxacin
43 Study to Evaluate Safety and Effectiveness of AdvaCoat Sinus Gel Completed NCT00554190 Phase 4
44 Use of Probiotics as Adjunctive Treatment for Chronic Rhinosinusitis Completed NCT00396162 Phase 4 probiotic containing L.rhamnosus R0011 strain
45 Treatment of Acute Sinusitis Completed NCT00377403 Phase 4 Acetaminophen;Amoxicillin;Dextromethorphan hydrobromide with guaifenesin;Guaifenesin;Pseudoephedrine Sustained Action;Saline spray (0.65%)
46 Zmax Compared to Augmentin in Sinusitis Completed NCT00367120 Phase 4 Azithromycin Extended Release;Amoxicillin/Clavulanate
47 Hemostatic Matrix in Endoscopic Sinus Surgery Completed NCT00242437 Phase 4
48 CHOOSE : Telithromycin, Acute Bacterial Sinusitis Completed NCT00174694 Phase 4 Telithromycin
49 Comparison Study Between Cefdinir & Amoxicilline/Clavulanate in Acute Sinusitis and Assessment of Quality of Life Completed NCT00147914 Phase 4 Cefdinir (drug);amoxicillin/clavulanate
50 Systemic Corticosteroids in the Perioperative Management of Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) Completed NCT02119273 Phase 4 Prednisone;Placebo

Search NIH Clinical Center for Nose Disease

Cochrane evidence based reviews: nose diseases

Genetic Tests for Nose Disease

Genetic tests related to Nose Disease:

# Genetic test Affiliating Genes
1 Abnormality of the Nose 29

Anatomical Context for Nose Disease

MalaCards organs/tissues related to Nose Disease:

41
Testes, Skin, Lung, Bone, Eye, Pituitary, Colon

Publications for Nose Disease

Articles related to Nose Disease:

# Title Authors Year
1
Blue nose disease in the horse. ( 18124494 )
1949

Variations for Nose Disease

Expression for Nose Disease

Search GEO for disease gene expression data for Nose Disease.

Pathways for Nose Disease

Pathways related to Nose Disease according to GeneCards Suite gene sharing:

(show all 24)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.95 CCL11 CD79A CXCL8 IL10 IL13 IL4
2
Show member pathways
13.31 CCL11 CXCL8 IL10 IL13 IL4 IL5
3
Show member pathways
12.78 CCL11 CXCL8 IL10 IL13 IL4 IL5
4
Show member pathways
12.58 CXCL8 IL10 IL13 IL4 IL5 TSLP
5
Show member pathways
12.49 CD79A IL13 IL4 IL5 MS4A2
6
Show member pathways
12.33 IL10 IL13 IL4 IL5
7
Show member pathways
12.21 CCL11 CXCL8 IL13 IL4 IL5 MUC5B
8
Show member pathways
12.11 CCL11 CXCL8 IL4 TLR9
9 12.09 CXCL8 IL10 IL13 TAC1
10
Show member pathways
12.03 CCL11 CXCL8 IL10 IL13 IL4 IL5
11 11.94 CD79A IL10 IL4 IL5 PTGDR2
12 11.91 CCL11 CXCL8 IL10 IL13 IL4
13 11.76 CXCL8 IL13 IL4 IL5
14
Show member pathways
11.66 CXCL8 IL4 IL5
15 11.62 CCL11 IL10 IL4 IL5
16 11.49 CXCL8 IL10 IL13 IL4
17 11.45 CXCL8 IL10 TLR9
18 11.42 CCL11 CXCL8 TSLP
19 11.34 IL10 IL13 IL4 IL5 PTGDR2 TSLP
20 11.22 CCL11 IL10 IL13 IL4 IL5
21 11.17 IL13 IL4 IL5 TSLP
22 11.1 IL10 IL13 IL4 IL5
23 10.97 IL10 IL13 IL4 IL5
24 10.9 CCL11 CXCL8 IL13 IL4 IL5 MUC5B

GO Terms for Nose Disease

Cellular components related to Nose Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 CCL11 CXCL8 IL10 IL13 IL4 IL5
2 external side of plasma membrane GO:0009897 9.46 CD79A IL13 MS4A2 TRPV1
3 extracellular space GO:0005615 9.36 CCL11 CXCL8 IL10 IL13 IL4 IL5

Biological processes related to Nose Disease according to GeneCards Suite gene sharing:

(show all 21)
# Name GO ID Score Top Affiliating Genes
1 cell surface receptor signaling pathway GO:0007166 9.88 CD79A CYSLTR1 MS4A2 TRPV1
2 response to lipopolysaccharide GO:0032496 9.85 CXCL8 IL10 IL13 TAC1
3 cytokine-mediated signaling pathway GO:0019221 9.8 CCL11 CXCL8 IL10 IL13 IL4 IL5
4 regulation of signaling receptor activity GO:0010469 9.8 CCL11 CXCL8 IL10 IL13 IL4 IL5
5 chemotaxis GO:0006935 9.78 CCL11 CXCL8 CYSLTR1 PTGDR2
6 neuropeptide signaling pathway GO:0007218 9.77 CYSLTR1 PTGDR2 TAC1
7 B cell differentiation GO:0030183 9.74 CD79A IL10 IL4
8 negative regulation of endothelial cell apoptotic process GO:2000352 9.61 IL10 IL13 IL4
9 positive regulation of macrophage activation GO:0043032 9.59 IL10 IL13
10 microglial cell activation GO:0001774 9.58 IL13 TRPV1
11 positive regulation of interleukin-13 production GO:0032736 9.56 IL4 TSLP
12 immune response GO:0006955 9.56 CCL11 CXCL8 IL10 IL13 IL4 IL5
13 positive regulation of immunoglobulin production GO:0002639 9.54 IL13 TLR9
14 response to molecule of bacterial origin GO:0002237 9.54 CXCL8 IL10 TLR9
15 positive regulation of MHC class II biosynthetic process GO:0045348 9.52 IL10 IL4
16 type 2 immune response GO:0042092 9.51 IL10 IL4
17 negative regulation of interleukin-8 production GO:0032717 9.49 IL10 TLR9
18 regulation of isotype switching GO:0045191 9.46 IL10 IL4
19 positive regulation of B cell proliferation GO:0030890 9.46 IL13 IL4 IL5 TLR9
20 negative regulation of complement-dependent cytotoxicity GO:1903660 9.4 IL13 IL4
21 inflammatory response GO:0006954 9.32 CCL11 CXCL8 HRH1 IL10 IL13 IL5

Molecular functions related to Nose Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.17 CCL11 CXCL8 IL10 IL13 IL4 IL5

Sources for Nose Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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