MCID: NSP004
MIFTS: 22

Nosophobia

Categories: Mental diseases

Aliases & Classifications for Nosophobia

MalaCards integrated aliases for Nosophobia:

Name: Nosophobia 12 15 17

Classifications:



External Ids:

Disease Ontology 12 DOID:0060048

Summaries for Nosophobia

Disease Ontology : 12 A specific phobia that involves an irrational fear of contracting a disease.

MalaCards based summary : Nosophobia is related to hypochondriasis and neurotic disorder. An important gene associated with Nosophobia is MCIDAS (Multiciliate Differentiation And DNA Synthesis Associated Cell Cycle Protein), and among its related pathways/superpathways is BRCA1 Pathway. Affiliated tissues include heart, and related phenotypes are Negative genetic interaction between KRASG13D/+ and KRAS+/- and Decreased viability with cisplatin

Wikipedia : 74 Nosophobia is the irrational fear of contracting a disease, a type of specific phobia. Primary fears of... more...

Related Diseases for Nosophobia

Diseases related to Nosophobia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 45)
# Related Disease Score Top Affiliating Genes
1 hypochondriasis 10.2
2 neurotic disorder 10.2
3 fallopian tube clear cell adenocarcinoma 10.2 BRCA2 BRCA1
4 rare malignant breast tumor 10.2 BRCA2 BRCA1
5 synchronous bilateral breast carcinoma 10.2 BRCA2 BRCA1
6 ovary transitional cell carcinoma 10.2 BRCA2 BRCA1
7 hereditary site-specific ovarian cancer syndrome 10.2 BRCA2 BRCA1
8 familial ovarian cancer 10.2 BRCA2 BRCA1
9 tetraploidy 10.2 BRCA2 BRCA1
10 basaloid lung carcinoma 10.2 BRCA2 BRCA1
11 breast-ovarian cancer, familial 2 10.2 BRCA2 BRCA1
12 endosalpingiosis 10.2 BRCA2 BRCA1
13 ovarian carcinosarcoma 10.2 BRCA2 BRCA1
14 cervical adenoma malignum 10.2 BRCA2 BRCA1
15 b-lymphoblastic leukemia/lymphoma with hyperdiploidy 10.2 BRCA2 BRCA1
16 mutagen sensitivity 10.2 BRCA2 BRCA1
17 primary peritoneal carcinoma 10.2 BRCA2 BRCA1
18 dysplastic nevus syndrome 10.2 BRCA2 BRCA1
19 breast-ovarian cancer, familial 1 10.2 BRCA2 BRCA1
20 hypertrophy of breast 10.2 BRCA2 BRCA1
21 female reproductive endometrioid cancer 10.2 BRCA2 BRCA1
22 peritoneum cancer 10.2 BRCA2 BRCA1
23 premature menopause 10.2 BRCA2 BRCA1
24 papillary serous adenocarcinoma 10.1 BRCA2 BRCA1
25 lobular neoplasia 10.1 BRCA2 BRCA1
26 fallopian tube disease 10.1 BRCA2 BRCA1
27 thoracic benign neoplasm 10.1 BRCA2 BRCA1
28 fanconi anemia, complementation group d1 10.1 BRCA2 BRCA1
29 myasthenic syndrome, congenital, 6, presynaptic 10.1 BRCA2 BRCA1
30 breast benign neoplasm 10.1 BRCA2 BRCA1
31 fanconi anemia, complementation group j 10.1 BRCA2 BRCA1
32 ovarian cystadenocarcinoma 10.1 BRCA2 BRCA1
33 uterine corpus cancer 10.1 BRCA2 BRCA1
34 papillary adenocarcinoma 10.1 BRCA2 BRCA1
35 bilateral breast cancer 10.1 BRCA2 BRCA1
36 dysgerminoma 10.1 BRCA2 BRCA1
37 fallopian tube carcinoma 10.0 BRCA2 BRCA1
38 female breast cancer 10.0 BRCA2 BRCA1
39 serous cystadenocarcinoma 10.0 BRCA2 BRCA1
40 pre-malignant neoplasm 10.0 BRCA2 BRCA1
41 sporadic breast cancer 9.9 BRCA2 BRCA1
42 in situ carcinoma 9.9 BRCA2 BRCA1
43 breast carcinoma in situ 9.8 BRCA2 BRCA1
44 ovary adenocarcinoma 9.7 BRCA2 BRCA1
45 cancerophobia 8.4 SFTA3 SCN2B POGLUT1 MCIDAS MAPK8IP1 BRCA2

Graphical network of the top 20 diseases related to Nosophobia:



Diseases related to Nosophobia

Symptoms & Phenotypes for Nosophobia

GenomeRNAi Phenotypes related to Nosophobia according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Negative genetic interaction between KRASG13D/+ and KRAS+/- GR00255-A-5 9.26 BRCA1 BRCA2 EXOC1 MAPK8IP1
2 Decreased viability with cisplatin GR00101-A-4 9.16 BRCA1 BRCA2
3 Synthetic lethal with cisplatin GR00101-A-1 8.62 BRCA1 BRCA2

MGI Mouse Phenotypes related to Nosophobia:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.1 BRCA1 BRCA2 MAPK8IP1 MCIDAS POGLUT1 SCN2B

Drugs & Therapeutics for Nosophobia

Search Clinical Trials , NIH Clinical Center for Nosophobia

Genetic Tests for Nosophobia

Anatomical Context for Nosophobia

MalaCards organs/tissues related to Nosophobia:

40
Heart

Publications for Nosophobia

Articles related to Nosophobia:

(show all 12)
# Title Authors PMID Year
1
Illness behavior. 61
22056904 2012
2
[Anxiety, depression, panic disorder and bronchial asthma]. 61
22201083 2011
3
Psychosomatic characterization of adjustment disorders in the medical setting: some suggestions for DSM-V. 61
17196662 2007
4
[Thanatophobia in the patients on dialysis]. 61
16683410 2006
5
[Management of chronic headache]. 61
11139742 2000
6
PET study and neuropsychological assessment of a long-lasting post-encephalitic parkinsonism. 61
9720976 1998
7
A tentative classification of "neuroses" based on behavioristic consideration of the pathogenetic mechanisms. 61
8201788 1993
8
[Therapeutic neglect omission of individual treatment of secondary defective developments]. 61
549047 1979
9
[Relationship between the unconscious and motivation in establishing a therapeutic program]. 61
652866 1978
10
NOSOPHOBIA AND HYPOCHONDRIASIS IN MEDICAL STUDENTS. 61
14206454 1964
11
Fear, anxiety and cardiac nosophobia (cardiac neurosis) associated with electrocardiographic T wave directional changes. 61
13657210 1959
12
Nosophobia. 61
18866779 1948

Variations for Nosophobia

Expression for Nosophobia

Search GEO for disease gene expression data for Nosophobia.

Pathways for Nosophobia

Pathways related to Nosophobia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.54 BRCA2 BRCA1

GO Terms for Nosophobia

Cellular components related to Nosophobia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lateral element GO:0000800 8.62 BRCA2 BRCA1

Biological processes related to Nosophobia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 double-strand break repair GO:0006302 9.26 BRCA2 BRCA1
2 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.16 BRCA2 BRCA1
3 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 8.96 BRCA2 BRCA1
4 chordate embryonic development GO:0043009 8.62 BRCA2 BRCA1

Sources for Nosophobia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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