Aliases & Classifications for Nut Allergy

MalaCards integrated aliases for Nut Allergy:

Name: Nut Allergy 12 77 15
Nut Allergic Reaction 12 17
Nut Hypersensitivity 45 74
Allergy to Nuts 12
Allergy Nut 56

Classifications:



External Ids:

Disease Ontology 12 DOID:4379
MeSH 45 D021184
SNOMED-CT 69 91934008
UMLS 74 C0577620

Summaries for Nut Allergy

Disease Ontology : 12 A food allergy that develops_from exposure to and particularly consumption of nuts, and has symptom asthma, skin rashes, throat and eye irritation, and anaphylaxis.

MalaCards based summary : Nut Allergy, also known as nut allergic reaction, is related to egg allergy and allergic hypersensitivity disease, and has symptoms including asthma An important gene associated with Nut Allergy is STAT6 (Signal Transducer And Activator Of Transcription 6), and among its related pathways/superpathways is Th2 Differentiation Pathway. The drugs English walnut and Cefpodoxime have been mentioned in the context of this disorder. Affiliated tissues include skin, eye and testes, and related phenotype is immune system.

Wikipedia : 77 A tree nut allergy is a hypersensitivity to dietary substances from tree nuts and edible tree seeds... more...

Related Diseases for Nut Allergy

Graphical network of the top 20 diseases related to Nut Allergy:



Diseases related to Nut Allergy

Symptoms & Phenotypes for Nut Allergy

Symptoms:

12
  • asthma

MGI Mouse Phenotypes related to Nut Allergy:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.17 ENPP3 FOXP3 IL5 PTGDR2 SCP2 STAT6

Drugs & Therapeutics for Nut Allergy

Drugs for Nut Allergy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 English walnut Approved Phase 1, Phase 2,Phase 2,Not Applicable
2
Cefpodoxime Approved, Vet_approved Not Applicable 80210-62-4, 82619-04-3 6335986
3
tannic acid Approved Not Applicable 1401-55-4
4
Benzocaine Approved, Investigational Not Applicable 1994-09-7, 94-09-7 2337
5 Cefpodoxime proxetil Not Applicable
6 Soy Bean Not Applicable

Interventional clinical trials:

(show all 18)
# Name Status NCT ID Phase Drugs
1 Walnut Oral Immunotherapy for Tree Nut Allergy Active, not recruiting NCT01546753 Phase 1, Phase 2 Walnut Protein Powder;Oat Powder (placebo)
2 Walnut Oral Immunotherapy for Tree Nut Allergy Withdrawn NCT01834352 Phase 1, Phase 2 Walnut Protein Flour;Oat flour
3 Trichuris Suis Ova in Peanut and Tree Nut Allergy Completed NCT01070498 Phase 1 Trichuris suis ova (TSO)
4 Tree Nuts Allergies: Does a Single Nut Allergy Necessitate the Dietary Eviction of Other Tree Nuts? Completed NCT01744990 Not Applicable
5 Nut Allergy Study: Double-blind Challenge and Oral Desensitization Completed NCT01502878 Not Applicable
6 Visual Recognition of Allergens by Allergic Patients and/or Their Parents Completed NCT02966938
7 Anxiety About Casual Exposure to Food Allergens Completed NCT03349047 Not Applicable
8 Phenotypical Characterization of Peanut Allergic Children Completed NCT02961452
9 Immunologic Profile of Children With Severe Allergies to Peanuts and Nuts After Induction of Tolerance Completed NCT01996774
10 One-year Survey of Anaphylaxis in Outpatient Children Allergic to Peanuts, Walnuts/Hazelnuts, Shellfish Completed NCT02640560
11 Potential Allergens in Wine: Double-blind Placebo-controlled Trial Completed NCT00163735 Not Applicable Administration of wine fined with potential food allergens
12 Peanut and Tree Nut Desensitization Recruiting NCT03532360 Not Applicable
13 Study to Assess Tolerance of Traces in Peanut/Tree Nut Allergic Children. Recruiting NCT03680066 Not Applicable
14 Blood Samples for the Study of Peanut, Tree Nut and Other Food Allergies Recruiting NCT02192866
15 Basophil Activation Test to Diagnose Food Allergy Recruiting NCT03309488
16 The Effect of Per Oral Immunotherapy in Severe IgE Mediated Egg, Milk, and Nut Allergy in Adults Active, not recruiting NCT01822353 Not Applicable
17 Mixed Tree Nut Food Challenges Enrolling by invitation NCT02070263
18 Walnut Oral Immunotherapy for Tree Nut Allergy Withdrawn NCT01918657 Not Applicable walnut powder;walnut powder

Search NIH Clinical Center for Nut Allergy

Cochrane evidence based reviews: nut hypersensitivity

Genetic Tests for Nut Allergy

Anatomical Context for Nut Allergy

MalaCards organs/tissues related to Nut Allergy:

42
Skin, Eye, Testes, Liver, B Cells

Publications for Nut Allergy

Articles related to Nut Allergy:

(show top 50) (show all 94)
# Title Authors Year
1
An Approach to the Diagnostic Challenges of Tree Nut Allergy. ( 30973100 )
2019
2
Clinical presentation of cashew nut allergy in a paediatric cohort attending an allergy clinic in the West of Ireland. ( 29623581 )
2019
3
Tree nut allergy and anxiety related factors modulate food consumption behaviour in peanut-allergic patients: Results of the MIRABEL survey. ( 30253193 )
2018
4
Short-term ibrutinib therapy suppresses skin test responses and eliminates IgE-mediated basophil activation in adults with peanut or tree nut allergy. ( 29360526 )
2018
5
Management of nut allergy in primary care. ( 29371317 )
2018
6
Cashew nut allergy in Singaporean children. ( 30079307 )
2018
7
Threshold dose distribution for cashew nut allergy in children. ( 29671917 )
2018
8
Current perspectives on tree nut allergy: a review. ( 29618933 )
2018
9
Pine nut allergy in Korean children: Clinical characteristics and diagnostic values of specific IgE against pine nuts. ( 29395441 )
2018
10
Managing Nut Allergy: A Remaining Clinical Challenge. ( 27793601 )
2017
11
B-FAHF-2 plus oral immunotherapy (OIT) is safer and more effective than OIT alone in a murine model of concurrent peanut/tree nut allergy. ( 28397379 )
2017
12
Prediction of cashew nut allergy in sensitized children. ( 28423473 )
2017
13
Nut allergy guideline. ( 28574656 )
2017
14
Nut allergy guidelines discourage complete avoidance. ( 28584009 )
2017
15
Nut Allergy in Two Different Areas of Spain: Differences in Clinical and Molecular Pattern. ( 28825657 )
2017
16
BSACI guideline for the diagnosis and management of peanut and tree nut allergy. ( 28836701 )
2017
17
Pistachio nut allergy: An updated overview. ( 28925724 )
2017
18
Specific IgE to recombinant protein (Ber e 1) for the diagnosis of Brazil nut allergy. ( 26684696 )
2016
19
Nut allergy prevalence and differences between Asian-born children and Australian-born children of Asian descent: a state-wide survey of children at primary school entry in Victoria, Australia. ( 26728850 )
2016
20
Is Microarray Analysis Really Useful and Sufficient to Diagnose Nut Allergy in the Mediterranean Area? ( 27012014 )
2016
21
Cashew Nut Allergy: Clinical Relevance and Allergen Characterisation. ( 27585580 )
2016
22
Threshold dose distribution and eliciting dose of cashew nut allergy. ( 27773603 )
2016
23
Development of sesame tolerance and cosensitization of sesame allergy with peanut and tree nut allergy in children. ( 28073703 )
2016
24
Usefulness of open mixed nut challenges to exclude tree nut allergy in children. ( 26034579 )
2015
25
The Prevalence of Tree Nut Allergy: A Systematic Review. ( 26233427 )
2015
26
Tree nut allergy: risk factors for development, mitigation of reaction risk and current efforts in desensitization. ( 25824522 )
2015
27
Oral immunotherapy initiation for multi-nut allergy: a case report. ( 25838098 )
2015
28
A retrospective study of peanut and tree nut allergy: Sensitization and correlations with clinical manifestations. ( 25860169 )
2015
29
Peanut and tree nut allergy. ( 26022873 )
2015
30
A retrospective study of peanut and tree nut allergy: Sensitization and correlations with clinical manifestations. ( 25730137 )
2015
31
Cardiac mMCP-4+ mast cell expansion and elevation of IL-6, and CCR1/3 and CXCR2 signaling chemokines in an adjuvant-free mouse model of tree nut allergy. ( 25499102 )
2015
32
Dietary management of peanut and tree nut allergy: what exactly should patients avoid? ( 25443673 )
2015
33
High consumption of peanuts or tree nuts by non-allergic mothers around the time of pregnancy reduces the risk of nut allergy in the child. ( 24986044 )
2015
34
Particularities in a Child With Cashew Nut Allergy. ( 27335909 )
2014
35
Systematic review on cashew nut allergy. ( 24734868 )
2014
36
Prospective study of peripregnancy consumption of peanuts or tree nuts by mothers and the risk of peanut or tree nut allergy in their offspring. ( 24366539 )
2014
37
Identification of T- and B-Cell Subsets That Expand in the Central and Peripheral Lymphoid Organs during the Establishment of Nut Allergy in an Adjuvant-Free Mouse Model. ( 23724246 )
2013
38
Lipids are required for the development of Brazil nut allergy: the role of mouse and human iNKT cells. ( 23137012 )
2013
39
"Dude! You mean you've never eaten a peanut butter and jelly sandwich?!?" Nut allergy as stigma in comic books. ( 22574889 )
2013
40
Pine nut allergy: clinical features and major allergens characterization. ( 23081934 )
2012
41
Infant Feeding Practices and Nut Allergy over Time in Australian School Entrant Children. ( 22811733 )
2012
42
The psychological impact of diagnostic food challenges to confirm the resolution of peanut or tree nut allergy. ( 22093150 )
2012
43
Tree nut allergy, egg allergy, and asthma in children. ( 21098525 )
2011
44
A qualitative study of families of a child with a nut allergy. ( 21846662 )
2011
45
Basophil CD203c levels are increased at baseline and can be used to monitor omalizumab treatment in subjects with nut allergy. ( 20975283 )
2011
46
Characterizing the relationship between sesame, coconut, and nut allergy in children. ( 21073539 )
2010
47
How do we know when peanut and tree nut allergy have resolved, and how do we keep it resolved? ( 20645999 )
2010
48
Macadamia nut allergy: 2 case reports and a review of the literature. ( 20491364 )
2010
49
Macadamia nut allergy: potentially misleading specific IgE results. ( 20337625 )
2010
50
Management of nut allergy influences quality of life and anxiety in children and their mothers. ( 20088863 )
2010

Variations for Nut Allergy

Expression for Nut Allergy

Search GEO for disease gene expression data for Nut Allergy.

Pathways for Nut Allergy

Pathways related to Nut Allergy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.46 FOXP3 IL5 STAT6

GO Terms for Nut Allergy

Sources for Nut Allergy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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