MCID: NTR005
MIFTS: 58

Nutritional Deficiency Disease

Categories: Blood diseases, Immune diseases, Metabolic diseases

Aliases & Classifications for Nutritional Deficiency Disease

MalaCards integrated aliases for Nutritional Deficiency Disease:

Name: Nutritional Deficiency Disease 12 15
Nutrition 43 3
Carbamoyl-Phosphate Synthase I Deficiency Disease 73
Nutritional Deficiency 55
Nutritional Disorder 55
Deficiency Diseases 73
Nutrition Disorders 73
Malnutrition 73

Classifications:



External Ids:

Disease Ontology 12 DOID:5113
MeSH 44 D003677

Summaries for Nutritional Deficiency Disease

MedlinePlus : 43 Food provides the energy and nutrients you need to be healthy. Nutrients include proteins, carbohydrates, fats, vitamins, minerals, and water. Healthy eating is not hard. The key is to Eat a variety of foods, including vegetables, fruits, and whole-grain products Eat lean meats, poultry, fish, beans, and low-fat dairy products Drink lots of water Limit salt, sugar, alcohol, saturated fat, and trans fat in your diet Saturated fats are usually fats that come from animals. Look for trans fat on the labels of processed foods, margarines, and shortenings. Centers for Disease Control and Prevention

MalaCards based summary : Nutritional Deficiency Disease, also known as nutrition, is related to marasmus and peripheral nervous system disease, and has symptoms including nausea and vomiting, constipation and abdominal pain. An important gene associated with Nutritional Deficiency Disease is TF (Transferrin), and among its related pathways/superpathways are Glucose / Energy Metabolism and Selenium Micronutrient Network. Affiliated tissues include liver, thyroid and kidney, and related phenotypes are Reduced mammosphere formation and cardiovascular system

Wikipedia : 76 Malnutrition is a condition that results from eating a diet in which one or more nutrients are either... more...

Related Diseases for Nutritional Deficiency Disease

Diseases related to Nutritional Deficiency Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1918)
# Related Disease Score Top Affiliating Genes
1 marasmus 32.7 ALB IGF1 IGFBP3 TF TTR
2 peripheral nervous system disease 31.9 ALB IL6 TTR
3 iron deficiency anemia 31.0 CRP EPO HAMP IL6 TF TMPRSS6
4 keratomalacia 30.9 TF TTR
5 secondary hyperparathyroidism of renal origin 30.7 ALB BGLAP EPO
6 hypothyroidism 30.6 IGF1 IGFBP3 LEP LHX3 TTR
7 decubitus ulcer 30.5 ALB CRP TTR
8 vitamin b12 deficiency 30.5 EPO MTHFR TF
9 protein-energy malnutrition 30.4 ALB CP IGF1 IL6 LEP TF
10 myeloma, multiple 30.4 ALB CRP EPO IGF1 IL6
11 liver cirrhosis 30.3 ALB IGFBP3 LEP TF TTR
12 hypopituitarism 30.3 IGF1 IGFBP3 LHX3
13 ariboflavinosis 30.2 ALB MTHFR TF
14 polycystic ovary syndrome 30.2 IGF1 IGFBP1 LEP
15 kidney disease 30.2 ALB CRP EPO IL6 TF TTR
16 respiratory failure 30.2 ALB CRP TTR
17 diabetes mellitus, noninsulin-dependent 30.1 ALB CRP GHRL IGF1 IGFBP1 IGFBP3
18 peripheral vascular disease 30.1 ALB CRP IL6
19 wilson disease 30.1 ALB CP TF
20 body mass index quantitative trait locus 11 30.1 CRP GHRL IGF1 IGFBP1 IGFBP3 IL6
21 heart disease 30.1 ALB CRP IGF1 IL6 MTHFR
22 brain injury 30.1 EPO IGF1 IL6
23 iron metabolism disease 30.1 CP EPO TF
24 hyperthyroidism 30.1 BGLAP GHRL LEP
25 acquired immunodeficiency syndrome 30.0 ALB EPO IL6
26 analbuminemia 30.0 ALB CRP EPO TF TTR
27 uremia 30.0 ALB CRP EPO LEP TF
28 peritonitis 30.0 ALB CRP IL6
29 diabetes mellitus, insulin-dependent 30.0 ALB BGLAP IGF1 IGFBP1 IGFBP3 IL6
30 arteries, anomalies of 30.0 ALB CRP IL6 LEP
31 hyperinsulinism 30.0 GHRL IGF1 IGFBP1 IGFBP3 LEP
32 diabetes mellitus 29.9 ALB CP CRP EPO GHRL IGF1
33 juvenile rheumatoid arthritis 29.9 BGLAP CRP IL6
34 homocysteinemia 29.8 ALB CRP MTHFR
35 exudative vitreoretinopathy 1 29.8 EPO IGF1 IGFBP3
36 intestinal disease 29.8 ALB CRP GHRL IL6
37 end stage renal failure 29.8 ALB CRP EPO IL6 LEP TF
38 sleep disorder 29.8 CRP IL6 LEP
39 osteoporotic fracture 29.8 IL6 MTHFR
40 dysentery 29.8 ALB CRP TF TTR
41 kwashiorkor 29.8 ALB TF TTR
42 periodontitis 29.7 BGLAP CRP IL6
43 obstructive jaundice 29.7 ALB CRP IL6 TTR
44 intermittent claudication 29.7 ALB CRP IL6
45 gastroenteritis 29.7 ALB CRP IL6
46 morbid obesity 29.7 CRP GHRL LEP
47 ischemic heart disease 29.6 CRP IL6 MTHFR
48 inherited metabolic disorder 29.6 CRP HAMP LEP MTHFR TF
49 folic acid deficiency anemia 29.6 CRP EPO TF
50 fetal macrosomia 29.6 IGF1 IGFBP3 LEP

Comorbidity relations with Nutritional Deficiency Disease via Phenotypic Disease Network (PDN): (show all 12)


Active Peptic Ulcer Disease Acute Cystitis
Alzheimer Disease Decubitus Ulcer
Deficiency Anemia Familial Atrial Fibrillation
Heart Disease Iron Deficiency Anemia
Osteoporosis Protein-Energy Malnutrition
Schizophreniform Disorder Swallowing Disorders

Graphical network of the top 20 diseases related to Nutritional Deficiency Disease:



Diseases related to Nutritional Deficiency Disease

Symptoms & Phenotypes for Nutritional Deficiency Disease

UMLS symptoms related to Nutritional Deficiency Disease:


nausea and vomiting, constipation, abdominal pain, cachexia, diarrhea, abdominal symptom, decrease in appetite

GenomeRNAi Phenotypes related to Nutritional Deficiency Disease according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.17 ALB GHRL IGF1 IGFBP3 MVK PMVK

MGI Mouse Phenotypes related to Nutritional Deficiency Disease:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.81 CP CRP EPO IGF1 IGFBP3 IL6
2 homeostasis/metabolism MP:0005376 9.8 ALB CP CRP EPO GHRL IGF1
3 adipose tissue MP:0005375 9.73 CP GHRL IGF1 IGFBP3 IL6 LEP
4 liver/biliary system MP:0005370 9.28 ALB CP EPO IGFBP1 IGFBP3 IL6

Drugs & Therapeutics for Nutritional Deficiency Disease

Genetic Tests for Nutritional Deficiency Disease

Anatomical Context for Nutritional Deficiency Disease

MalaCards organs/tissues related to Nutritional Deficiency Disease:

41
Liver, Thyroid, Kidney, Lung, Bone, Heart, Pituitary

Publications for Nutritional Deficiency Disease

Articles related to Nutritional Deficiency Disease:

(show top 50) (show all 994)
# Title Authors Year
1
Nutrition in Alcoholic Liver Disease: An Update. ( 30454836 )
2019
2
Developing a Novel Ambulatory Total Parenteral Nutrition-Dependent Short Bowel Syndrome Animal Model. ( 30527464 )
2019
3
Prevalence and Types of School-Based Out-of-School Time Programs at Elementary Schools and Implications for Student Nutrition and Physical Activity. ( 30506694 )
2019
4
Teachers' Perceived and Desired Roles in Nutrition Education. ( 30506698 )
2019
5
Nutrition Support is a Potential Confounding Factor for the Relationship Between Body Weight Variation and the Risk of Bedsore. ( 30557254 )
2019
6
Contraction and nutrition interaction promotes anabolism in cachectic muscle. ( 30461449 )
2019
7
The relationships between blood lead levels and serum thyroid stimulating hormone and total thyroxine in the third National Health and Nutrition Examination Survey. ( 30466922 )
2019
8
Effect of cooking methods on solubility and nutrition quality of brown rice powder. ( 30372963 )
2019
9
Detarium microcarpum: A novel source of nutrition and medicine: A review. ( 30373026 )
2019
10
Multiple metal exposures and metabolic syndrome: A cross-sectional analysis of the National Health and Nutrition Examination Survey 2011-2014. ( 30388496 )
2019
11
Comment on "Early enteral nutrition is associated with reduced in-hospital mortality from sepsis in patients with sarcopenia". ( 30391113 )
2019
12
Editorial: From old to new: roles of protein sources and individual amino acids in clinical nutrition. ( 30394892 )
2019
13
An update to the fatty acid profiles of bovine retail milk in the United Kingdom: Implications for nutrition in different age and gender groups. ( 30409587 )
2019
14
Resolving design issues in developing a nutrition app: A case study using formative research. ( 30321688 )
2019
15
Circulating small non-coding RNAs provide new insights into vitamin K nutrition and reproductive physiology in teleost fish. ( 30268730 )
2019
16
In vivo endogenous proteolysis yielding beta-casein derived bioactive beta-casomorphin peptides in human breast milk for infant nutrition. ( 30199719 )
2019
17
Nutrition support team activities can improve enteral nutrition administration in intensive care units. ( 30219684 )
2019
18
Association of oral contraceptive use with suicidal behavior among representative Korean population: Results from Korea National Health and Nutrition Examination Survey (2007-2016). ( 30219691 )
2019
19
Relationship between mortality and Council of Nutrition Appetite Questionnaire scores in Japanese nursing home residents. ( 30153578 )
2019
20
Is continuing medical education sufficient? Assessing the clinical nutrition knowledge of medical doctors. ( 30153582 )
2019
21
Acrodermatitis enteropathica from zinc-deficient total parenteral nutrition. ( 30063773 )
2018
22
Acquired bullous acrodermatitis enteropathica as a histologic mimic of pemphigus foliaceus in a patient on parenteral nutrition. ( 30142747 )
2018
23
Efficacy comparisons of enteral nutrition and parenteral nutrition in patients with severe acute pancreatitis: a meta-analysis from randomized controlled trials. ( 30333259 )
2018
24
Early Enteral Nutrition Prevent Acute Pancreatitis From Deteriorating in Obese Patients. ( 30106837 )
2018
25
Enteral nutrition provided within 48 hours after admission in severe acute pancreatitis: A systematic review and meta-analysis. ( 30142782 )
2018
26
Classification and Nutrition Management of Acute Pancreatitis in the Pediatric Intensive Care Unit. ( 30211843 )
2018
27
Unraveling Methodology to Ensure the Search for Optimal Nutrition Quantity in Acute Respiratory Distress Syndrome Remains INTACT. ( 30251261 )
2018
28
Effects of Preoperative Enteral Nutrition on Postoperative Recent Nutritional Status in Patients with Siewert II and III Adenocarcinoma of Esophagogastric Junction after Neoadjuvant Chemoradiotherapy. ( 30273016 )
2018
29
Serum Marker Score Based on Prognostic Nutrition Index, Carcinoembryonic Antigen, and Carbohydrate Antigen 19-9 Is Associated With Recurrence for Patients Undergoing Surgery for Pancreatic Ductal Adenocarcinoma. ( 30161074 )
2018
30
Adherence to Nutrition and Physical Activity Cancer Prevention Guidelines and Development of Colorectal Adenoma. ( 30115827 )
2018
31
Adequacy of nutrition and body weight in patients with early stage dementia: The cognition and aging study. ( 30316533 )
2018
32
Adherence to Appropriate Nutrition in Acute Alcoholic Hepatitis is Low. ( 30145576 )
2018
33
Nutrition and Alzheimer Disease. ( 30336995 )
2018
34
Altered host-gut microbes symbiosis in severely malnourished anorexia nervosa (AN) patients undergoing enteral nutrition: An explicative factor of functional intestinal disorders? ( 30527539 )
2018
35
Enteral Nutrition via Nasogastric Tube for Refeeding Patients With Anorexia Nervosa: A Systematic Review. ( 30070730 )
2018
36
Relationship between rheumatoid arthritis and periodontal disease in Korean adults: Data from the Sixth Korea National Health and Nutrition Examination Survey, 2013 to 2015. ( 30380152 )
2018
37
Rheumatoid arthritis is associated with early tooth loss: results from Korea National Health and Nutrition Examination Survey V to VI. ( 30257550 )
2018
38
Prevalence rates of arthritis among US older adults with varying degrees of depression: Findings from the 2011 to 2014 National Health and Nutrition Examination Survey. ( 30229563 )
2018
39
Are we really what we eat? Nutrition and its role in the onset of rheumatoid arthritis. ( 30213695 )
2018
40
A novel semi-solidifying liquid formula via the nasogastric route to maintain enteral nutrition in the event of recurrent aspiration pneumonia: A case report. ( 30214747 )
2018
41
The impact of maternal smoking during pregnancy on childhood asthma: adjusted for exposure misclassification; results from the National Health and Nutrition Examination Survey, 2011-2012. ( 30150159 )
2018
42
Parental smoking and depression, and attention-deficit hyperactivity disorder in children and adolescents: Korean national health and nutrition examination survey 2005-2014. ( 30088339 )
2018
43
Enteral Nutrition Initiation in Children Admitted to Pediatric Intensive Care Units After Traumatic Brain Injury. ( 30171446 )
2018
44
Fluctuations of Nutrition-Associated Markers After Decompressive Hemicraniectomy in Middle Cerebral Artery Occlusion Patients. ( 30178320 )
2018
45
Cholangiocarcinoma: Treatment, Outcomes, and Nutrition Overview for Oncology Nurses. ( 30035775 )
2018
46
Fish oil-based lipid emulsion in the treatment of parenteral nutrition-associated cholestasis. ( 30139361 )
2018
47
Effects of two different lipid emulsions on antioxidant status, lipid peroxidation and parenteral nutrition- related cholestasis in premature babies, a randomized-controlled study. ( 30177465 )
2018
48
Plasma Phytosterol Half-Life and Levels Are Increased in Very Low Birth Weight Preterm Infants with Parenteral Nutrition-Associated Cholestasis. ( 30187918 )
2018
49
Enteral fish oil supplementation in the resolution of parenteral nutrition associated cholestasis. ( 30373963 )
2018
50
Can mixed lipid emulsion prevent parenteral nutrition associated cholestasis? ( 30455473 )
2018

Variations for Nutritional Deficiency Disease

Expression for Nutritional Deficiency Disease

Search GEO for disease gene expression data for Nutritional Deficiency Disease.

Pathways for Nutritional Deficiency Disease

GO Terms for Nutritional Deficiency Disease

Cellular components related to Nutritional Deficiency Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endoplasmic reticulum lumen GO:0005788 9.56 ALB BGLAP CP GHRL IGFBP1 IGFBP3
2 extracellular space GO:0005615 9.5 ALB BGLAP CP CRP EPO GHRL
3 insulin-like growth factor ternary complex GO:0042567 9.32 IGF1 IGFBP3
4 insulin-like growth factor binding protein complex GO:0016942 9.26 IGF1 IGFBP3
5 extracellular region GO:0005576 10 ALB BGLAP CP CRP EPO GHRL

Biological processes related to Nutritional Deficiency Disease according to GeneCards Suite gene sharing:

(show all 19)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.91 ALB EPO GHRL IGF1 IL6 LEP
2 post-translational protein modification GO:0043687 9.88 ALB CP IGFBP1 IGFBP3 IL6 TF
3 aging GO:0007568 9.81 BGLAP EPO HAMP IGFBP1
4 positive regulation of MAPK cascade GO:0043410 9.78 IGF1 IGFBP3 IL6 LEP
5 cholesterol metabolic process GO:0008203 9.73 LEP MVK PMVK
6 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.73 EPO IGF1 IL6 LEP
7 response to estrogen GO:0043627 9.71 BGLAP EPO GHRL
8 response to nutrient levels GO:0031667 9.7 BGLAP GHRL LEP
9 regulation of signaling receptor activity GO:0010469 9.7 EPO GHRL HAMP IGF1 IL6 LEP
10 cellular iron ion homeostasis GO:0006879 9.62 CP HAMP TF TMPRSS6
11 isoprenoid biosynthetic process GO:0008299 9.58 MVK PMVK
12 positive regulation of cell growth involved in cardiac muscle cell development GO:0061051 9.58 HAMP IGF1
13 positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 9.57 IGF1 IGFBP3
14 adult feeding behavior GO:0008343 9.55 GHRL LEP
15 bone mineralization involved in bone maturation GO:0035630 9.49 IGF1 LEP
16 isopentenyl diphosphate biosynthetic process, mevalonate pathway GO:0019287 9.46 MVK PMVK
17 negative regulation of lipid storage GO:0010888 9.43 CRP IL6 LEP
18 acute-phase response GO:0006953 9.26 CRP EPO HAMP IL6
19 cellular protein metabolic process GO:0044267 9.23 ALB CP IGF1 IGFBP1 IGFBP3 IL6

Molecular functions related to Nutritional Deficiency Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 insulin-like growth factor I binding GO:0031994 9.16 IGFBP1 IGFBP3
2 hormone activity GO:0005179 9.1 EPO GHRL HAMP IGF1 LEP TTR
3 insulin-like growth factor II binding GO:0031995 8.96 IGFBP1 IGFBP3

Sources for Nutritional Deficiency Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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