MCID: NTR005
MIFTS: 60

Nutritional Deficiency Disease

Categories: Blood diseases, Immune diseases, Metabolic diseases

Aliases & Classifications for Nutritional Deficiency Disease

MalaCards integrated aliases for Nutritional Deficiency Disease:

Name: Nutritional Deficiency Disease 12 15 17
Nutritional Disorder 56 17
Nutrition 44 3
Carbamoyl-Phosphate Synthase I Deficiency Disease 74
Nutritional Deficiency 56
Deficiency Diseases 74
Nutrition Disorders 74
Malnutrition 74

Classifications:



Summaries for Nutritional Deficiency Disease

MedlinePlus : 44 Food provides the energy and nutrients you need to be healthy. Nutrients include proteins, carbohydrates, fats, vitamins, minerals, and water. Healthy eating is not hard. The key is to Eat a variety of foods, including vegetables, fruits, and whole-grain products Eat lean meats, poultry, fish, beans, and low-fat dairy products Drink lots of water Limit salt, sugar, alcohol, saturated fat, and trans fat in your diet Saturated fats are usually fats that come from animals. Look for trans fat on the labels of processed foods, margarines, and shortenings. Centers for Disease Control and Prevention

MalaCards based summary : Nutritional Deficiency Disease, also known as nutritional disorder, is related to marasmus and peripheral nervous system disease, and has symptoms including nausea and vomiting, constipation and abdominal pain. An important gene associated with Nutritional Deficiency Disease is TTR (Transthyretin), and among its related pathways/superpathways are Selenium Micronutrient Network and Senescence and Autophagy in Cancer. The drugs leucovorin and Zinc have been mentioned in the context of this disorder. Affiliated tissues include kidney, bone and heart, and related phenotypes are Reduced mammosphere formation and homeostasis/metabolism

Disease Ontology : 12 A nutrition disease that is characterized by deficiency of a nutritional element, such as a vitamin, mineral, carbohydrate, protein, fat, or general energy content.

Wikipedia : 77 Malnutrition is a condition that results from eating a diet in which one or more nutrients are either... more...

Related Diseases for Nutritional Deficiency Disease

Diseases related to Nutritional Deficiency Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 2019)
# Related Disease Score Top Affiliating Genes
1 marasmus 32.8 ALB IGF1 IGFBP3 TF TTR
2 peripheral nervous system disease 32.0 ALB IL6 TTR
3 respiratory failure 32.0 ALB CRP TTR
4 ariboflavinosis 32.0 ALB MTHFR TF
5 folic acid deficiency anemia 31.6 CBLIF CRP EPO TF
6 body mass index quantitative trait locus 11 31.4 CRP GHRL IGF1 IGFBP1 IGFBP3 IL6
7 iron deficiency anemia 31.0 CRP EPO HAMP IL6 TF TMPRSS6
8 decubitus ulcer 30.9 ALB CRP TTR
9 protein-energy malnutrition 30.8 ALB CP IGF1 IL6 LEP TF
10 hypothyroidism 30.8 IGF1 IGFBP3 LEP LHX3 TTR
11 liver cirrhosis 30.7 ALB IGFBP3 LEP TF TTR
12 vitamin b12 deficiency 30.7 EPO MTHFR TF
13 iron metabolism disease 30.6 CP EPO TF
14 hypopituitarism 30.5 IGF1 IGFBP3 LHX3
15 myeloma, multiple 30.4 ALB CRP EPO IGF1 IL6
16 acquired immunodeficiency syndrome 30.4 ALB EPO IL6
17 brain injury 30.4 EPO IGF1 IL6
18 intermittent claudication 30.4 ALB CRP IL6
19 hyperthyroidism 30.4 BGLAP GHRL LEP
20 kidney disease 30.4 ALB CRP EPO IL6 TF TTR
21 arteries, anomalies of 30.3 ALB CRP IL6 LEP
22 heart disease 30.3 ALB CRP IGF1 IL6 MTHFR
23 diabetes mellitus, insulin-dependent 30.3 ALB GHRL IGF1 IGFBP1 IGFBP3 IL6
24 uremia 30.3 ALB CRP EPO LEP TF
25 gastroenteritis 30.3 ALB CRP IL6
26 diabetes mellitus, noninsulin-dependent 30.2 ALB CRP GHRL IGF1 IGFBP1 IGFBP3
27 homocysteinemia 30.2 ALB CRP MTHFR
28 peritonitis 30.2 ALB CRP IL6
29 peripheral vascular disease 30.2 ALB CRP IL6
30 periodontitis 30.2 BGLAP CRP IL6
31 juvenile rheumatoid arthritis 30.2 BGLAP CRP IL6
32 exudative vitreoretinopathy 1 30.1 EPO IGF1 IGFBP3
33 analbuminemia 30.1 ALB CRP EPO TF TTR
34 hyperinsulinism 30.1 GHRL IGF1 IGFBP1 IGFBP3 LEP
35 dysentery 30.1 ALB CRP TF TTR
36 obstructive jaundice 30.0 ALB CRP IL6 TTR
37 ischemic heart disease 30.0 CRP IL6 MTHFR
38 kwashiorkor 30.0 ALB TF TTR
39 end stage renal failure 30.0 ALB CRP EPO IL6 LEP TF
40 sleep disorder 30.0 CRP IL6 LEP
41 intestinal disease 30.0 ALB CRP GHRL IL6
42 wilson disease 30.0 ALB CP TF
43 acute cystitis 29.9 ALB CRP IL6
44 osteoporotic fracture 29.8 IL6 MTHFR
45 morbid obesity 29.8 CRP GHRL LEP
46 pulmonary embolism 29.8 ALB CRP MTHFR
47 fetal macrosomia 29.8 IGF1 IGFBP3 LEP
48 bone fracture 29.8 BGLAP CRP
49 glucose intolerance 29.8 CRP GHRL IGF1 IGFBP1 LEP
50 inherited metabolic disorder 29.8 CRP HAMP LEP MTHFR TF

Comorbidity relations with Nutritional Deficiency Disease via Phenotypic Disease Network (PDN): (show all 12)


Active Peptic Ulcer Disease Acute Cystitis
Alzheimer Disease Decubitus Ulcer
Deficiency Anemia Familial Atrial Fibrillation
Heart Disease Iron Deficiency Anemia
Osteoporosis Protein-Energy Malnutrition
Schizophreniform Disorder Swallowing Disorders

Graphical network of the top 20 diseases related to Nutritional Deficiency Disease:



Diseases related to Nutritional Deficiency Disease

Symptoms & Phenotypes for Nutritional Deficiency Disease

UMLS symptoms related to Nutritional Deficiency Disease:


nausea and vomiting, constipation, abdominal pain, cachexia, diarrhea, abdominal symptom, decrease in appetite

GenomeRNAi Phenotypes related to Nutritional Deficiency Disease according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.17 ALB GHRL IGF1 IGFBP3 MVK PMVK

MGI Mouse Phenotypes related to Nutritional Deficiency Disease:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.83 ALB CBLIF CP CRP EPO GHRL
2 adipose tissue MP:0005375 9.63 CP GHRL IGF1 IGFBP3 IL6 LEP
3 liver/biliary system MP:0005370 9.32 ALB CBLIF CP EPO IGFBP1 IGFBP3

Drugs & Therapeutics for Nutritional Deficiency Disease

Drugs for Nutritional Deficiency Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 972)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
leucovorin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 58-05-9 6006 143
2
Zinc Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 7440-66-6 32051
3
Zinc sulfate Approved, Investigational Phase 4,Phase 2,Phase 3 7733-02-0
4
Moxonidine Approved, Investigational Phase 4 75438-57-2 4810
5
tannic acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1401-55-4
6
Tocopherol Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 1406-66-2 14986
7
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 94-09-7, 1994-09-7 2337
8
Dexmedetomidine Approved, Vet_approved Phase 4,Not Applicable 113775-47-6 68602 5311068
9
Dalteparin Approved Phase 4,Phase 1 9005-49-6
10
Enoxaparin Approved Phase 4,Phase 1,Phase 2 9005-49-6 772
11
Methylcobalamin Approved, Experimental, Investigational Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1 13422-55-4
12
Hydroxocobalamin Approved Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1 13422-51-0 11953898 15589840
13
chenodeoxycholic acid Approved Phase 4 474-25-9 10133
14
Octreotide Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 83150-76-9 6400441 383414
15
Rocuronium Approved Phase 4,Phase 2,Not Applicable 119302-91-9, 143558-00-3 441290
16
Morphine Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 57-27-2 5288826
17
Metformin Approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 657-24-9 14219 4091
18
Parathyroid hormone Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 9002-64-6
19
Acarbose Approved, Investigational Phase 4 56180-94-0 441184
20
Vildagliptin Approved, Investigational Phase 4 274901-16-5 6918537
21
Coal tar Approved Phase 4,Phase 1,Phase 2,Not Applicable 8007-45-2
22
Chlorhexidine Approved, Vet_approved Phase 4,Not Applicable 55-56-1 2713 9552079
23
Irbesartan Approved, Investigational Phase 4,Not Applicable 138402-11-6 3749
24
Angiotensin II Approved, Investigational Phase 4,Phase 2,Phase 3,Early Phase 1,Not Applicable 68521-88-0, 11128-99-7, 4474-91-3 172198 65143
25
Anastrozole Approved, Investigational Phase 4,Not Applicable 120511-73-1 2187
26
Saxagliptin Approved Phase 4 361442-04-8 11243969
27
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3,Phase 2 58-93-5 3639
28
Enalaprilat Approved Phase 4 76420-72-9 6917719
29
Amlodipine Approved Phase 4,Phase 2,Phase 3 88150-42-9 2162
30
Enalapril Approved, Vet_approved Phase 4 75847-73-3 5362032 40466924
31
Copper Approved, Investigational Phase 4,Phase 2,Not Applicable 7440-50-8 27099
32
Iron Approved, Experimental Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 7439-89-6, 15438-31-0 23925 27284
33
Nadroparin Approved, Investigational Phase 4
34
Heparin Approved, Investigational Phase 4,Not Applicable 9005-49-6 772 46507594
35
Dinoprostone Approved Phase 4 363-24-6 5280360
36
Calcium Carbonate Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 471-34-1
37
Iodine Approved, Investigational Phase 4,Phase 2,Not Applicable 7553-56-2 807
38
Nicotinamide Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable,Early Phase 1 98-92-0 936
39
Selenium Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 7782-49-2
40
Sodium Citrate Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 68-04-2
41
Exenatide Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 141758-74-9 15991534
42
Acetaminophen Approved Phase 4,Phase 3,Phase 1,Not Applicable,Early Phase 1 103-90-2 1983
43
Liraglutide Approved Phase 4,Phase 3,Phase 2,Phase 1 204656-20-2 44147092
44
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 2078-54-8 4943
45
Testosterone Approved, Experimental, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 58-22-0, 481-30-1 6013 10204
46
Testosterone enanthate Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 315-37-7 9416
47
Methyltestosterone Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 58-18-4 6010
48
Testosterone undecanoate Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 5949-44-0
49
Midazolam Approved, Illicit Phase 4,Phase 2,Phase 1,Not Applicable 59467-70-8 4192
50
Ethanol Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 64-17-5 702

Interventional clinical trials:

(show top 50) (show all 4371)
# Name Status NCT ID Phase Drugs
1 Folic Acid Supplementation as an Appetizer in Primary Malnourished Egyptian Infants and Children Unknown status NCT03040219 Phase 4 Folic Acid
2 Effect of Zinc Supplementation on Appetite and Growth in Primary Malnourished Children Unknown status NCT03098810 Phase 4 Zinc sulphate
3 Nutritional Supplementation in Patients With no Signs of Malnutrition Unknown status NCT01894828 Phase 4
4 Effects of Nutritional Supplementation in Malnourished Patients in Stable COPD Unknown status NCT02197871 Phase 4
5 Enteral Nutrition After Cardiovascular Surgery Unknown status NCT01432769 Phase 4
6 Comparison of Meal Replacements Versus Protein Supplements and Utilizing the Protein Digestibility Corrected Amino Acid Score (PDCAAS) Method Unknown status NCT01399333 Phase 4
7 Study of the Effect of Moxonidine and Diet on Sympathetic Functions in Young Adults With Obesity Unknown status NCT01180231 Phase 4 Moxonidine (Physiotens)
8 Determination of Vitamin D Dose to Maintain Sufficiency Amongst Indian and Malay Women in the Tropics Unknown status NCT02389179 Phase 4 Vitamin D3
9 Vitamin D and Inflammatory Markers of Cardiovascular Disease in African Americans With Type 2 Diabetes Unknown status NCT01153243 Phase 4 Ergocalciferol;Placebo pill
10 The Effect of Obesity in Dexmedetomidine Metabolic Clearance Unknown status NCT02557867 Phase 4 Dexmedetomidine
11 Obesity Cohort : Medical Follow-up of Severe or Morbid Obese Patients Undergoing Bariatric Surgery Unknown status NCT02310178 Phase 4
12 The Therapeutic Effect of Catgut Embedding in Obesity Unknown status NCT02276235 Phase 4
13 Probiotics Use in the Chronic Peritoneal Dialysis Patients Unknown status NCT01076426 Phase 4 Pro-biotics
14 Prevention and Control of Obesity in Primary School Children in Tehran Unknown status NCT02082080 Phase 4
15 Anti Xa Levels Under Two Different Regimens of Enoxaparin VTE Prophylaxis After Sleeve Gastrectomy for Morbid Obesity Unknown status NCT01970202 Phase 4 40mg Enoxaparin;60mg Enoxaparin
16 Pharmacokinetics of Dexmedetomidine in Morbid Obesity Unknown status NCT01864187 Phase 4 Dexmedetomidine
17 Evaluation of the Effects of Laying Early a Gastric Band on the Prevention of Morbid Obesity Randomized Checked Against Standard Management of Obesity in This Population. Unknown status NCT01700738 Phase 4
18 Impact of the Preservation of the Gastric Antrum in the Technique of Sleeve Gastrectomy for the Treatment of the Morbid Obesity Unknown status NCT01550601 Phase 4
19 The Effect of Vitamin A Supplementation on Cytokine Profile in Obesity Unknown status NCT01405352 Phase 4
20 Efficacy of KCl Plus 0.9%NaCl Compare With KCl Plus 0.45%NaCl Unknown status NCT02721095 Phase 4
21 Comparison of Enteral Versus Intravenous Potassium Supplementation Unknown status NCT02015962 Phase 4 Intravenous potassium chloride;Oral potassium chloride
22 How Many Patients Are in Need of Vitamin B12 Injections? Unknown status NCT00326833 Phase 4 vitamin B12
23 Egg Albumin-Based Protein Supplement Versus Renal-specific Supplement in Hemodialysis Patients Unknown status NCT01981083 Phase 4
24 Effect of Bile Acids and Bile Acid Sequstrants on GLP-1 Secretion After Roux-en-Y Gastric Bypass Unknown status NCT02952963 Phase 4 Chenodeoxycholic Acid;Colesevelam
25 Effects of Bile Acids and Bile Acid Sequestrants on GLP-1 Secretion After Roux-en-Y Gastric Bypass Unknown status NCT02876484 Phase 4 Colesevelam;Chenodeoxycholic Acid
26 Gut Hormones as Mediators of Different Weight Loss Responses After Roux-en-Y Gastric Bypass Unknown status NCT02374632 Phase 4
27 Laparoscopic Bariatric Surgery: Impact of Deep Neuromuscular Block on Surgical Conditions Unknown status NCT02118844 Phase 4 rocuronium
28 VAS Correlation With BMI Unknown status NCT02017314 Phase 4 Morphine
29 Banded Versus Conventional Laparoscopic Roux-en-Y (GABY) Unknown status NCT01015469 Phase 4
30 Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Sleeve Gastrectomy Unknown status NCT00667706 Phase 4
31 The Effect of a Diet Based on Low Sodium and Slowly Absorbed Carbohydrates on the Incidence of Refeeding Syndrome in Patients With Head and Neck Cancer Unknown status NCT01845922 Phase 4
32 Value Antiproteinuric Effects From Vitamin D Derivatives in Patient With Chronic Kidney Illness and the Lack of Vitamin D Unknown status NCT01442272 Phase 4 Hidroferol®;Paricalcitol: Zemplar®;Habitual medication
33 Study of Efficacy of Metformin in the Treatment of Acanthosis Nigricans in Children With Obesity Unknown status NCT02438020 Phase 4 Metformin
34 Vitamin Deficiencies and Suppletion in Morbid Obesity Unknown status NCT02270749 Phase 4 Hydroxocobalamin;FitForMe vitamin B12
35 Optimizing Treatment Programs for Chronic Kidney Disease-mineral and Bone Disorder and Malnutrition Unknown status NCT02005302 Phase 4 1,25(OH)2 Vitamin D3;Vitamin D2
36 Effect of Laparoscopic Sleeve Gastrectomy in the Morbidly Obese, Kidney Transplant Candidate Unknown status NCT01913392 Phase 4
37 Effect of Acarbose and Vildagliptin on Visceral Fat Distribution in Newly Diagnosed Type 2 Diabetes Patients Unknown status NCT02999841 Phase 4 Acarbose;Vildagliptin
38 Trial Comparing Metformin Versus Placebo in Non Alcoholic Steatohepatitis (NASH) Patients Receiving Bariatric Surgery for Obesity Unknown status NCT00134303 Phase 4 Metformin
39 Treatment of Periodontitis in Obese Individuals Unknown status NCT03103204 Phase 4
40 Vitamin D Deficiency and Postoperative Hypocalcemia Unknown status NCT01632514 Phase 4 Cholecalciferol
41 Cholecalciferol Supplementation in Restless Leg Syndrome in Patients With Chronic Kidney Disease Unknown status NCT03063190 Phase 4 Vitamin D;Placebo Oral Tablet
42 The Effect of Moxonidine on Blood Pressure and Regression of Early Target Organ Damage in Young Subjects With Abdominal Obesity and Hypertension Unknown status NCT01360710 Phase 4 Moxonidine;Irbesartan
43 Aromatase Inhibitors and Weight Loss in Severely Obese Hypogonadal Male Veterans (Pilot) Unknown status NCT02959853 Phase 4 Anastrazole
44 Effects of Cholecalciferol on Osteoprotegerin Levels in Patients on Peritoneal Dialysis Unknown status NCT02598635 Phase 4 Cholecalciferol;Placebo
45 Effect of Saxagliptin on Pre-Diabetes Mellitus and Obesity Unknown status NCT01960205 Phase 4 Saxagliptin;saxagliptin;metformin
46 Feasibility Study of the Intensive Systolic Blood Pressure Control Unknown status NCT02817503 Phase 4 Standard BP control;Moderate BP control;Intensive BP control
47 Trial of Captafer® vs. Oral Iron Sulfate in the Treatment of Iron Deficiency Anemia in Patients With IBD Unknown status NCT02774057 Phase 4 Captafer®;Iron Sulfate
48 Prophylaxis of Venous Thromboembolism After Bariatric Surgery Unknown status NCT02295150 Phase 4 Nadroparin
49 A Prospective, Randomized, Controlled, Multicenter Study of Kanglaite Injection for the Treatment of Cancer Cachexia Unknown status NCT02553187 Phase 4 Kanglaite Injection
50 Treatment Response of Injectafer vs Oral Iron to Baseline Hepcidin Levels in Patients With Iron Deficiency Anemia (IDA) Secondary to Inflammatory Bowel Disease (IBD) or Gastric Bypass Unknown status NCT02086968 Phase 4 Injectafer;Ferrous Sulfate tablets

Search NIH Clinical Center for Nutritional Deficiency Disease

Inferred drug relations via UMLS 74 / NDF-RT 52 :


Genetic Tests for Nutritional Deficiency Disease

Anatomical Context for Nutritional Deficiency Disease

MalaCards organs/tissues related to Nutritional Deficiency Disease:

42
Kidney, Bone, Heart, Liver, Testes, Lung, Brain

Publications for Nutritional Deficiency Disease

Articles related to Nutritional Deficiency Disease:

# Title Authors Year
1
Skin manifestations of nutritional deficiency disease in children: modern day contexts. ( 23171006 )
2012
2
Vitamin C deficiency: more than just a nutritional disorder. ( 21614623 )
2011
3
Toddler diarrhoea: more a nutritional disorder than a disease. ( 9771243 )
1998
4
Nutritional disorder of anorexia nervosa: a review. ( 8173564 )
1994
5
The influence of nutritional disorder on the lipid composition of the central nervous system. ( 5697552 )
1968
6
Strachan's syndrome. A nutritional disorder of the nervous system. ( 5743948 )
1968
7
The nutritional disorder in anorexia nervosa. ( 6049025 )
1967
8
Obesity as a nutritional disorder. ( 13672278 )
1959
9
Principles underlying the early diagnosis of nutritional deficiency disease. ( 21016693 )
1946
10
LEAF-WRINKLE, A NUTRITIONAL DISORDER OF SOY BEAN. ( 16652839 )
1933

Variations for Nutritional Deficiency Disease

Expression for Nutritional Deficiency Disease

Search GEO for disease gene expression data for Nutritional Deficiency Disease.

Pathways for Nutritional Deficiency Disease

GO Terms for Nutritional Deficiency Disease

Cellular components related to Nutritional Deficiency Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.83 ALB BGLAP CBLIF CP CRP EPO
2 endoplasmic reticulum lumen GO:0005788 9.76 ALB BGLAP CP GHRL IGFBP1 IGFBP3
3 extracellular space GO:0005615 9.53 ALB BGLAP CBLIF CP CRP EPO
4 insulin-like growth factor ternary complex GO:0042567 9.32 IGF1 IGFBP3
5 insulin-like growth factor binding protein complex GO:0016942 9.26 IGF1 IGFBP3

Biological processes related to Nutritional Deficiency Disease according to GeneCards Suite gene sharing:

(show all 19)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.91 ALB EPO GHRL IGF1 IL6 LEP
2 post-translational protein modification GO:0043687 9.88 ALB CP IGFBP1 IGFBP3 IL6 TF
3 aging GO:0007568 9.81 BGLAP EPO HAMP IGFBP1
4 positive regulation of MAPK cascade GO:0043410 9.78 IGF1 IGFBP3 IL6 LEP
5 cholesterol metabolic process GO:0008203 9.73 LEP MVK PMVK
6 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.73 EPO IGF1 IL6 LEP
7 response to estrogen GO:0043627 9.71 BGLAP EPO GHRL
8 response to nutrient levels GO:0031667 9.7 BGLAP GHRL LEP
9 regulation of signaling receptor activity GO:0010469 9.7 EPO GHRL HAMP IGF1 IL6 LEP
10 cellular iron ion homeostasis GO:0006879 9.62 CP HAMP TF TMPRSS6
11 isoprenoid biosynthetic process GO:0008299 9.58 MVK PMVK
12 positive regulation of cell growth involved in cardiac muscle cell development GO:0061051 9.58 HAMP IGF1
13 positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 9.57 IGF1 IGFBP3
14 adult feeding behavior GO:0008343 9.55 GHRL LEP
15 bone mineralization involved in bone maturation GO:0035630 9.49 IGF1 LEP
16 isopentenyl diphosphate biosynthetic process, mevalonate pathway GO:0019287 9.46 MVK PMVK
17 negative regulation of lipid storage GO:0010888 9.43 CRP IL6 LEP
18 acute-phase response GO:0006953 9.26 CRP EPO HAMP IL6
19 cellular protein metabolic process GO:0044267 9.23 ALB CP IGF1 IGFBP1 IGFBP3 IL6

Molecular functions related to Nutritional Deficiency Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 insulin-like growth factor I binding GO:0031994 9.16 IGFBP1 IGFBP3
2 hormone activity GO:0005179 9.1 EPO GHRL HAMP IGF1 LEP TTR
3 insulin-like growth factor II binding GO:0031995 8.96 IGFBP1 IGFBP3

Sources for Nutritional Deficiency Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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