Nutritional Deficiency Disease

Categories: Metabolic diseases

Aliases & Classifications for Nutritional Deficiency Disease

MalaCards integrated aliases for Nutritional Deficiency Disease:

Name: Nutritional Deficiency Disease 12 15 17
Nutritional Disorder 54 17
Malnutrition 70 32
Carbamoyl-Phosphate Synthase I Deficiency Disease 70
Nutritional Deficiency 54
Deficiency Diseases 70
Nutrition Disorders 70
Nutrition 42


External Ids:

Disease Ontology 12 DOID:5113
MeSH 44 D003677
UMLS 70 C0011156 C0162429 C0751753 more

Summaries for Nutritional Deficiency Disease

MedlinePlus : 42 Food provides the energy and nutrients you need to be healthy. Nutrients include proteins, carbohydrates, fats, vitamins, minerals, and water. Healthy eating is not hard. The key is to Eat a variety of foods, including vegetables, fruits, and whole-grain products Eat lean meats, poultry, fish, beans, and low-fat dairy products Drink lots of water Limit salt, sugar, alcohol, saturated fat, and trans fat in your diet Saturated fats are usually fats that come from animals. Look for trans fat on the labels of processed foods, margarines, and shortenings. Centers for Disease Control and Prevention

MalaCards based summary : Nutritional Deficiency Disease, also known as nutritional disorder, is related to short bowel syndrome and folic acid deficiency anemia, and has symptoms including nausea and vomiting, constipation and abdominal pain. An important gene associated with Nutritional Deficiency Disease is TTR (Transthyretin), and among its related pathways/superpathways are Glucose / Energy Metabolism and Selenium Micronutrient Network. The drugs Hydrocortisone and Hydrocortisone acetate have been mentioned in the context of this disorder. Affiliated tissues include liver, bone and skeletal muscle, and related phenotypes are Reduced mammosphere formation and homeostasis/metabolism

Disease Ontology : 12 A nutrition disease that is characterized by deficiency of a nutritional element, such as a vitamin, mineral, carbohydrate, protein, fat, or general energy content.

Wikipedia : 73 Malnutrition is a condition that results from eating a diet which does not supply a healthy amount of... more...

Related Diseases for Nutritional Deficiency Disease

Diseases related to Nutritional Deficiency Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1779)
# Related Disease Score Top Affiliating Genes
1 short bowel syndrome 32.3 TTR LEP IL6 IGF1 GHRL CCK
2 folic acid deficiency anemia 32.3 HAMP EPO CRP
3 bone disease 32.1 IL6 IGF1 EPO BGLAP
4 iron deficiency anemia 31.9 TF IL6 HAMP GHRL EPO CRP
5 protein-energy malnutrition 31.9 TTR TF RBP4 LEP IL6 IGF1
6 respiratory failure 31.8 TTR TF RBP4 IL6 EPO CRP
7 perinatal necrotizing enterocolitis 31.6 IL6 CRP ALB
8 beta-thalassemia 31.6 TF MTHFR IL6 IGFBP3 IGF1 HAMP
9 lipid metabolism disorder 31.5 RBP4 LEP IL6 CRP ADIPOQ
10 ileus 31.4 IL6 GHRL CRP CCK
11 hyperglycemia 31.4 LEP IL6 IGF1 GHRL CCK ALB
12 constipation 31.4 IL6 GHRL CRP CCK ALB
13 insulin-like growth factor i 31.4 LEP IGFBP3 IGFBP1 IGF1 BGLAP
14 metabolic acidosis 31.3 IL6 IGF1 BGLAP ALB
15 intestinal obstruction 31.3 IL6 GHRL CRP ALB
16 aspiration pneumonia 31.3 IL6 CRP ALB
17 traumatic brain injury 31.3 IL6 IGF1 EPO
18 brain injury 31.2 IL6 IGF1 EPO ALB
19 thrombophlebitis 31.2 MTHFR CRP ALB
20 esophageal cancer 31.2 MTHFR LEP IL6 IGFBP3 IGF1 CRP
21 decubitus ulcer 31.2 TTR IL6 IGF1 CRP ALB
22 gestational diabetes 31.2 RBP4 LEP IL6 IGFBP1 CRP ADIPOQ
23 cholelithiasis 31.2 LEP CRP CCK ALB
24 cholecystitis 31.1 CP CCK ALB
25 hepatic encephalopathy 31.1 TTR IL6 ALB
26 phenylketonuria 31.1 TTR MTHFR GHRL BGLAP ALB
27 bilirubin metabolic disorder 31.1 IL6 EPO CRP CP ALB
28 acquired immunodeficiency syndrome 31.1 IL6 IGF1 EPO CRP ALB
29 hyperuricemia 31.1 MTHFR LEP CRP ALB
30 arteriosclerosis 31.1 TTR IL6 GHRL CRP ADIPOQ
31 gastroesophageal reflux 31.1 IL6 GHRL CCK ADIPOQ
32 congestive heart failure 31.1 IL6 EPO CRP ALB
33 exanthem 31.1 IL6 CRP ALB
34 uremia 31.1 LEP IL6 EPO CRP ALB
35 celiac disease 1 31.1 IL6 IGF1 GHRL CRP CCK ALB
36 peripheral vascular disease 31.0 MTHFR IL6 EPO CRP ALB
37 hyperinsulinism 31.0 LEP IGFBP3 IGFBP1 IGF1 GHRL ADIPOQ
38 homocysteinemia 31.0 MTHFR CRP ALB
39 cerebral palsy 31.0 MTHFR LEP IL6 IGFBP3 IGF1 BGLAP
40 end stage renal disease 31.0 TTR MTHFR LEP IL6 EPO CRP
41 irritable bowel syndrome 31.0 IL6 GHRL CRP CCK
42 exudative vitreoretinopathy 1 31.0 IL6 IGFBP3 IGF1 EPO
43 neutropenia 30.9 IL6 EPO CRP CP ALB
44 gastroenteritis 30.9 IL6 CRP ALB
45 non-alcoholic steatohepatitis 30.9 IL6 IGF1 GHRL ALB ADIPOQ
46 bulimia nervosa 30.9 LEP GHRL CCK
47 hyperphosphatemia 30.9 CRP BGLAP ALB
48 placenta disease 30.9 MTHFR IL6 CRP ADIPOQ
49 rare hereditary hemochromatosis 30.9 TF HAMP
50 angina pectoris 30.9 IL6 CRP ADIPOQ

Comorbidity relations with Nutritional Deficiency Disease via Phenotypic Disease Network (PDN): (show all 12)

Active Peptic Ulcer Disease Acute Cystitis
Alzheimer Disease Decubitus Ulcer
Deficiency Anemia Familial Atrial Fibrillation
Heart Disease Iron Deficiency Anemia
Osteoporosis Protein-Energy Malnutrition
Schizophreniform Disorder Swallowing Disorders

Graphical network of the top 20 diseases related to Nutritional Deficiency Disease:

Diseases related to Nutritional Deficiency Disease

Symptoms & Phenotypes for Nutritional Deficiency Disease

UMLS symptoms related to Nutritional Deficiency Disease:

nausea and vomiting; constipation; abdominal pain; cachexia; diarrhea; abdominal symptom; decrease in appetite

GenomeRNAi Phenotypes related to Nutritional Deficiency Disease according to GeneCards Suite gene sharing:

# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.17 ALB GHRL IGF1 IGFBP3 PMVK RBP4

MGI Mouse Phenotypes related to Nutritional Deficiency Disease:

# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.25 ADIPOQ ALB BGLAP CCK CP CRP
2 cardiovascular system MP:0005385 10.21 ADIPOQ ALB CP CRP EPO IGF1
3 cellular MP:0005384 10.18 ADIPOQ ALB BGLAP CP EPO IGF1
4 adipose tissue MP:0005375 10.11 ADIPOQ BGLAP CP GHRL IGF1 IGFBP3
5 endocrine/exocrine gland MP:0005379 10.11 ADIPOQ ALB BGLAP CCK GHRL IGF1
6 immune system MP:0005387 10.03 ADIPOQ ALB BGLAP CCK CP CRP
7 liver/biliary system MP:0005370 9.81 ADIPOQ ALB CP EPO IGFBP1 IGFBP3
8 muscle MP:0005369 9.56 ADIPOQ ALB EPO IGF1 IGFBP3 IL6
9 renal/urinary system MP:0005367 9.23 ADIPOQ ALB CCK IGF1 IL6 LEP

Drugs & Therapeutics for Nutritional Deficiency Disease

Drugs for Nutritional Deficiency Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 948)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754
Hydrocortisone acetate Approved, Vet_approved Phase 4 50-03-3
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
Caffeine Approved Phase 4 58-08-2 2519
parecoxib Approved Phase 4 198470-84-7
Metyrapone Approved, Investigational Phase 4 54-36-4 4174
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
carbamide peroxide Approved Phase 4 124-43-6
Molybdenum Approved Phase 4 7439-98-7 185498
Calcium carbonate Approved, Investigational Phase 4 471-34-1
Magnesium oxide Approved Phase 4 1309-48-4 14792
Petrolatum Approved, Investigational Phase 4 8009-03-8
Lopinavir Approved Phase 4 192725-17-0 92727
Zidovudine Approved Phase 4 30516-87-1 35370
Ritonavir Approved, Investigational Phase 4 155213-67-5 392622
Lamivudine Approved, Investigational Phase 4 134678-17-4 60825
Taurolidine Approved, Investigational Phase 4 19388-87-5
Oxandrolone Approved, Investigational Phase 4 53-39-4 5878
Ursodeoxycholic acid Approved, Investigational Phase 4 128-13-2 31401
Phentermine Approved, Illicit Phase 4 122-09-8 4771
Micafungin Approved, Investigational Phase 4 235114-32-6 3081921 477468
Paclitaxel Approved, Vet_approved Phase 4 33069-62-4 36314
Carboplatin Approved Phase 4 41575-94-4 10339178 498142 38904
Mebendazole Approved, Vet_approved Phase 4 31431-39-7 4030
Tranexamic Acid Approved Phase 4 1197-18-8 5526
Thrombin Approved, Investigational Phase 4
Anti-inhibitor coagulant complex Approved, Investigational Phase 4
Pravastatin Approved Phase 4 81093-37-0 54687
Teduglutide Approved Phase 4 197922-42-2
Halofantrine Approved Phase 4 69756-53-2 37393
Polymyxin B Approved, Vet_approved Phase 4 1404-26-8
Lycopene Approved, Investigational Phase 4 502-65-8 446925
33 Cranberry Approved, Investigational Phase 4
Piperazine Approved, Vet_approved Phase 4 110-85-0 4837
35 Barley Approved Phase 4
Miltefosine Approved, Investigational Phase 4 58066-85-6 3600
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
Topiramate Approved Phase 4 97240-79-4 5284627
Propranolol Approved, Investigational Phase 4 525-66-6 4946
Lisinopril Approved, Investigational Phase 4 83915-83-7, 76547-98-3 5362119
Metoprolol Approved, Investigational Phase 4 51384-51-1, 37350-58-6 4171
Naltrexone Approved, Investigational, Vet_approved Phase 4 16590-41-3 5360515
Bupropion Approved Phase 4 34911-55-2, 34841-39-9 444
Atenolol Approved Phase 4 29122-68-7 2249
Titanium dioxide Approved Phase 4 13463-67-7
Simethicone Approved Phase 4 8050-81-5
Bromocriptine Approved, Investigational Phase 4 25614-03-3 31101
Metformin Approved Phase 4 657-24-9 14219 4091
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3

Interventional clinical trials:

(show top 50) (show all 5780)
# Name Status NCT ID Phase Drugs
1 Effect of Enteral Nutrition in the Outcome of Patients With Cardiovascular Surgery Unknown status NCT01432769 Phase 4
2 Effects of Nutritional Supplementation in Malnourished Patients in Stable COPD:a Randomised Controlled Trial Unknown status NCT02197871 Phase 4
3 Effectiveness Trial of Day-care Versus Usual Care Management of Severe Pneumonia With or Without Malnutrition in Children Using the Existing Health System of Bangladesh Unknown status NCT02669654 Phase 4
4 Impact of Immunonutrition on the Patients With Cystic Fibrosis Unknown status NCT02048592 Phase 4
5 The Effect of Nutritional Supplementation in Cancer Patients With no Clinical Signs of Malnutrition Unknown status NCT01894828 Phase 4
6 The Clinical Use of Probiotics in the Uremia Patients Under Chronic Peritoneal Dialysis Unknown status NCT01076426 Phase 4 Pro-biotics
7 Efficacy of Perioperative Application of Omega-3 Polyunsaturated Fatty Acids on Postoperative Immunization in Gastric Cancer Patients - A Prospective, Randomized Clinical Trial Unknown status NCT01910948 Phase 4 omega-3 polyunsaturated fatty acids
8 Randomized Clinical Trial of Omega-3 Fatty Acid-supplemented Parenteral Nutrition Versus Standard Parenteral Nutrition in Patients Undergoing Major Laparoscopic Abdominal Surgery Unknown status NCT01819961 Phase 4 MCT/LCT and fish oil;MCT/LCT
9 Randomized, Open Label, Controlled Clinical Trial of Egg Albumin-Based Protein Supplement Versus Renal Specific Oral Supplement in Hemodialysis Patients Unknown status NCT01981083 Phase 4
10 Randomized Cross-Over Trial of Captafer® vs. Oral Iron Sulfate in the Treatment of Iron Deficiency Anemia in Patients With Inflammatory Bowel Disease Unknown status NCT02774057 Phase 4 Captafer®;Iron Sulfate
11 Amino Acid Chelated Iron Versus Ferrous Fumarate in the Treatment of Iron Deficiency Anemia With Pregnancy: Randomized Controlled Trial Unknown status NCT03830034 Phase 4 Amino Acid chelated iron tab 15 mg;Ferrous Fumarate tab 350 mg( 115 mg elemental iron)
12 Randomized, Parallel Group, Clinical Trial Comparing Intravenous Iron Sucrose Versus Oral Ferrous Sulphate in the Treatment of Perioperative Iron Deficiency in Patients With Colo-Rectal Neoplasm and Iron Deficiency Anemia. Unknown status NCT00199277 Phase 4 i.v. iron sucrose;Oral iron
13 Effect of Enteral Genistein Supplementation on Inflammatory Cytokines, Morbidity and Mortality in Patients With Sepsis Unknown status NCT02796794 Phase 4
14 Comparative Study About the Impact of Two Oil Emulsions, One of Them Formulated With MCT, LCT, Olive Oil and Omega 3 Fatty Acids Versus Another One Formulated With MCT and LCT, Administered Intravenously on Severe Acute Pancreatitis Clinical Evolution Unknown status NCT01376817 Phase 4 Fat emulsion with MCT, LCT, olive oil and omega 3 fatty acids;Fat emulsion with MCT and LCT
15 Oxepa in Multiple Trauma: Prospective, Randomized, Comparative, Double-blind, Controlled Clinical Study Unknown status NCT01099501 Phase 4
16 Immuno-enhanced Versus Standard Early Enteral Nutrition Use in Gastrointestinal Postoperative Patients Unknown status NCT01778166 Phase 4 Immuno-enhanced;Standard early enteral nutrition
17 Fast-track Surgery Recovery Program With Early Jejunostomy Nutrition Protocol Minimizes Time to Adjuvant Chemotherapy in Patients Undergoing Laparoscopic Gastrectomy for Gastric Cancer Unknown status NCT01766765 Phase 4
18 A Double Blinded, Randomized, Controlled Investigation of Taurolidine-citrate/Heparin Catheter Lock Solution Versus Heparin in Patients on Home Parenteral Nutrition With Previously Proven High Risk of Catheter Related Blood Stream Infections. Unknown status NCT01948245 Phase 4
19 The Effects of Preventive Versus on Demand Nutritional Advice and Support on the Nutritional Status of Patients During Antiviral Therapy for Hepatitis C A Randomized, Multi Center Trial Unknown status NCT00841243 Phase 4
20 A Prospective, Controlled, Randomized, Study Evaluating the Clinical Efficacy, Including Nutritional Status, Immune Function and Safety of Omegaven (w-3 Fish Oil) Supplemented Parenteral Nutrition in Subjects of SICU. Unknown status NCT00172198 Phase 4 Omegaven 10%
21 Study of Vitamin D2 Virus 1,25(OH)2-Vitamin D3 and Normal Protein Diet Virus Low Protein Diet in the Treatment of CKD-MBD and Malnutrition for Progressive CKD Patients Unknown status NCT02005302 Phase 4 1,25(OH)2 Vitamin D3;Vitamin D2
22 Microbial Invasion During Parenteral Nutrition in Surgical Infants Receiving Glutamine. Unknown status NCT00647036 Phase 4 Dipeptiven (L-glutamine- Lalanine)
23 Comparison of Two Strategies for Glycemic Control in Acute Ischemic Stroke Unknown status NCT00747279 Phase 4 Intensive insulin therapy
24 Studying the Role of N-Acetyl Cysteine Either Alone or in Combination With Metronidazole in Treatment of Bacterial Vaginosis Unknown status NCT01841411 Phase 4 N-Acetyl cysteine;Metronidazole + N-Acetyl cysteine;metronidazole
25 Early Oral Versus Enteral Nutrition After Pancreatoduodenectomy for Periampullary Tumors: a Prospective, Randomized, Controlled Clinical Trial Unknown status NCT01642875 Phase 4
26 Healthy Opportunities for Physical Activity and Nutrition (HOP'N) After-School Project Unknown status NCT01015599 Phase 4
27 Effects of Parenteral Nutrition With Different Lipid Emulsions in Preterm Infants Unknown status NCT01683162 Phase 4 ClinOleic;Lipofundin;Intralipid
28 The Impact of the French National Program for Nutrition and Health Guidelines on Vascular Function Following a Standardised Breakfast:The Nutri-Vasc Study Unknown status NCT01579409 Phase 4
29 A Randomized, Controlled, Single-blind Study of Effects of Enteral Nutrition and Corticosteroid on Intestinal Flora in Induction Remission of Crohn Disease in Adult Unknown status NCT02056418 Phase 4 corticosteroid
30 Effect of COX-2 Selective Inhibitors on Postoperative Insulin Resistance, Tramadol PCA and Early Postoperative Enteral Nutrition in Patients After Gastrointestinal Laparoscopic Surgery Unknown status NCT01930318 Phase 4 parecoxib
31 Influence of Immune Nutrition Diet on 90-Day Outcomes in Patients Undergoing Radical Cystectomy and Bladder Substitutions: A Randomized Controlled Trial Unknown status NCT03147586 Phase 4 Bio-tech and omega-3 plus;placebo
32 Folic Acid Supplementation as an Appetizer in Primary Malnourished Egyptian Infants and Children Unknown status NCT03040219 Phase 4 Folic Acid
33 Granulocyte Colony Stimulating Factor Plus N-Acetyl Cysteine In Severe Alcoholic Hepatitis Unknown status NCT02971306 Phase 4 standard medical therapy;G-CSF;n-Acetylcysteine
34 Efficiency and Tolerance of a Small-peptide Enteral Feeding Formula Compared to a Whole-protein Formula in the Critically Ill Patient : a Prospective Randomized Trial Unknown status NCT01833624 Phase 4
35 Randomized Double Blinded Trial to Investigate Effects of an Enteral Nutritional Supplement Enriched With Eicosapentaenoic Acid on Body Composition,Complications,Stress Response,Immune Function & Quality of Life in After Esophagectomy Unknown status NCT00790140 Phase 4
36 The Effects of Cortisol Blockade on Nutritional Sympathetic Nervous System Responsiveness in Overweight and Obese Subjects With Metabolic Syndrome Unknown status NCT01620684 Phase 4 metyrapone;placebo
37 Eight Week Feasibility Study Enrolling Dry Eye Subjects Confirmed by Four of Seven Dianostic Markers Responding to Nutritional Therapy Unknown status NCT01561040 Phase 4
38 Phase 4 Study of Mechanisms of Low Protein Diet Supplemented With Ketoanalogs on Reducing Proteinuria and Maintaining Nutritional Status in Type 2 Diabetic Nephropathy Unknown status NCT01300273 Phase 4
39 Phase IV Study Comparing a Nutritional Anti-Inflammatory Treatment to Steroids for Pediatric Crohn's Disease - the Molecular Basis Unknown status NCT00265772 Phase 4 MODULEN IBD (R) (specific Enteral Nutrition);prednisolon
40 A Prospective, Randomized Controlled Open Research About the Impact of Nutritional Support on the Radiation Tolerance and Clinical Outcomes for Local Advanced Nasopharyngeal Carcinoma Patients Unknown status NCT02948699 Phase 4
41 Nutritional Based Protocol to Balance Serotonin for the Prevention or Reduced Frequency/Duration/Intensity of Migraines Unknown status NCT00363506 Phase 4
42 Adverse Effects of Glucocorticoid Therapy on Bone in Childhood Crohn's Disease Unknown status NCT00609752 Phase 4 prednisolone
43 H.O.P.E. Healing Optimization Through Preoperative Engagement: A Prospective Single Cohort Study to Evaluate the Effect of a Prehabilitation Program on Preoperative Outcomes in Upper GI Surgical Oncology Patients Unknown status NCT03642093 Phase 4
45 Non Randomized Controlled Intervention Study Comparing Two Interventions of Nutritional Supplement on Malnutrition, Health and Mortality in Children Aged 6 to 24 Month Hadjer-Lamis Region - Chad Completed NCT02085044 Phase 4
46 Immunogenicity of Combined Bivalent OPV and IPV Vaccines at 9 - 12 Months of Age Compared to bOPV Alone in Malnourished and Non-Malnourished Pakistani Infants. Completed NCT01695798 Phase 4
47 The Effect of Neutral Peritoneal Dialysis Solution With Minimal Glucose-Degradation-Product on the Fluid Status and Body Composition - A Randomized Control Trial Completed NCT00966615 Phase 4
48 Effects Of Standard And/Or Glutamine Dipeptide And/Or Omega-3 Fatty Ascid-Supplemented Parenteral Nutrition On Neutrophil Functions, Interleukin-8 Level And Length Of Stay-A Double Blind,Controlled, Randomized Study Completed NCT01831310 Phase 4
49 Effect of Extensively Hydrolyzed Liquid Human Milk Fortifier on Growth and Tolerance in Moderately Premature Infants Completed NCT02632266 Phase 4
50 Taste and Smell Changes in Testicular Cancer Patients Treated With Cisplatin Based Chemotherapy Completed NCT01641172 Phase 4

Search NIH Clinical Center for Nutritional Deficiency Disease

Inferred drug relations via UMLS 70 / NDF-RT 51 :

Beef prepartion
borage oil
Calcium caseinate
manganese chloride
manganese dioxide
manganese sulfate
Medium chain triglycerides
Selenious Acid
selenium sulfide
Sodium Iodide
Sodium iodide I123
sodium selenate

Genetic Tests for Nutritional Deficiency Disease

Anatomical Context for Nutritional Deficiency Disease

MalaCards organs/tissues related to Nutritional Deficiency Disease:

Liver, Bone, Skeletal Muscle, Heart, Lung, Skin, Colon

Publications for Nutritional Deficiency Disease

Articles related to Nutritional Deficiency Disease:

(show top 50) (show all 799)
# Title Authors PMID Year
Diet, Nutrition, Obesity, and Their Implications for COVID-19 Mortality: Development of a Marginalized Two-Part Model for Semicontinuous Data. 42
33439850 2021
Race, ethnicity, and racism in the nutrition literature: an update for 2020. 42
33274358 2020
COVID-19: Is there a role for immunonutrition in obese patient? 42
33160363 2020
Acute polyneuropathy in critically ill patients. 54 61
2351777 1990
Dietary riboflavin deficiency induces ariboflavinosis and esophageal epithelial atrophy in association with modification of gut microbiota in rats. 61
32458157 2021
All together now: regulation of the iron deficiency response. 61
33449088 2021
Characterization of iron reducibility of soy protein amyloid fibrils and their applications in iron fortification. 61
33711705 2021
Nutritional Deficiency Disease Secondary to ARFID Symptoms Associated with Autism and the Broad Autism Phenotype: A Qualitative Systematic Review of Case Reports and Case Series. 61
33221247 2021
Pellagra in South Africa from 1897 to 2019: a scoping review. 61
33769244 2021
In vitro bioaccessibility and bioavailability of iron from fenugreek, baobab and moringa. 61
32745843 2021
Restoring Good Health in Elderly with Diverse Gut Microbiome and Food Intake Restriction to Combat COVID-19. 61
33424043 2021
Prevalence of Anemia and Associated Risk Factors Among Non-Pregnant Women in Riyadh, Saudi Arabia: A Cross-Sectional Study. 61
33707967 2021
Revisiting the pathobiology of scurvy: a review of the literature in the context of a challenging case. 61
32154584 2020
Demographic, Clinical and Biochemical Characteristics of Pediatric Obesity: Interim Analysis of a Larger Prospective Study. 61
33415908 2020
The influence of short-term selenitetriglycerides supplementation on blood selenium, and hepatic, renal, metabolic and hematological parameters in dairy cows. 61
33480507 2020
Morpho-physiological retardations due to iron toxicity involve redox imbalance rather than photosynthetic damages in tomato. 61
32906022 2020
Zinc (Zn): The Last Nutrient in the Alphabet and Shedding Light on Zn Efficiency for the Future of Crop Production under Suboptimal Zn. 61
33142680 2020
A decision support system on the obesity management and consultation during childhood and adolescence using ontology and semantic rules. 61
32911081 2020
Implementation of a red blood cell-optical (RBO) channel for detection of latent iron deficiency anaemia by automated measurement of autofluorescence-emitting red blood cells. 61
32973246 2020
Iron Metabolism in Obesity and Metabolic Syndrome. 61
32752277 2020
Graphene-Based Biosensor for Early Detection of Iron Deficiency. 61
32630192 2020
Insights into basic science: what basic science can teach us about iron homeostasis in trauma patients. 61
31876785 2020
Manganese in Plants: From Acquisition to Subcellular Allocation. 61
32273877 2020
Remodeling of Root Growth Under Combined Arsenic and Hypoxia Stress Is Linked to Nutrient Deprivation. 61
33193499 2020
Iron in Health and Disease: An Update. 61
31520313 2020
32159642 2020
Interaction between adipocytes and high-density lipoprotein:new insights into the mechanism of obesity-induced dyslipidemia and atherosclerosis. 61
31842884 2019
Preliminary Studies on Biodegradable Zinc Oxide Nanoparticles Doped with Fe as a Potential Form of Iron Delivery to the Living Organism. 61
31823131 2019
Cachexia/Protein energy wasting syndrome in CKD: Causation and treatment. 61
31286575 2019
Micromotors for Active Delivery of Minerals toward the Treatment of Iron Deficiency Anemia. 61
31588746 2019
The effect of high-fat diet on the morphological properties of the forelimb musculature in hypertrophic myostatin null mice. 61
31198988 2019
The Analysis of Food Intake in Patients with Cirrhosis Waiting for Liver Transplantation: A Neglected Step in the Nutritional Assessment. 61
31618837 2019
Zinc biofortification of cereals-role of phosphorus and other impediments in alkaline calcareous soils. 61
30903431 2019
Effect of Moringa Oleifera leaf powder supplementation on reducing anemia in children below two years in Kisarawe District, Tanzania. 61
31428346 2019
Iron Deficiency as a Therapeutic Target in Cardiovascular Disease. 61
31466321 2019
Isolation and identification of iron-chelating peptides from casein hydrolysates. 61
30993279 2019
The different tolerance to magnesium deficiency of two grapevine rootstocks relies on the ability to cope with oxidative stress. 61
30991946 2019
Behavioral, socio-environmental, educational and demographic correlates of excess body weight in Italian adolescents and young adults. 61
30718143 2019
Quercetin inhibits intestinal non-haem iron absorption by regulating iron metabolism genes in the tissues. 61
29594477 2019
Early Neuropathy Related to Oxaliplatin Treatment in Advanced and Recurrent Colorectal Cancer. 61
30842168 2019
Glutamine Metabolism in Macrophages: A Novel Target for Obesity/Type 2 Diabetes. 61
30753258 2019
The Frequency of Anemia and Underlying Factors among Iranian Pregnant Women from Provinces with Different Maternal Mortality Rate. 61
31205889 2019
West Syndrome in an Infant With Vitamin B12 Deficiency Born to Autoantibodies Positive Mother. 61
31956646 2019
Taste perception and oral microbiota are associated with obesity in children and adolescents. 61
31509575 2019
Pellagra, a re-emerging disease: a case report of a girl from a community ravaged by insurgency. 61
31692657 2019
Genotype Variation in Rice (Oryza sativa L.) Tolerance to Fe Toxicity Might Be Linked to Root Cell Wall Lignification. 61
31244872 2019
Obese rats are more vulnerable to inflammation, genotoxicity and oxidative stress induced by coal dust inhalation than non-obese rats. 61
30179764 2018
Effect of malting period on physicochemical properties, minerals, and phytic acid of finger millet (Eleusine coracana) flour varieties. 61
30349675 2018
Overweight and Obesity: A major concern for health in India. 61
30393804 2018
Circulating regulatory T cells (Treg), leptin and induction of proinflammatory activity in obese Labrador Retriever dogs. 61
30078586 2018

Variations for Nutritional Deficiency Disease

Expression for Nutritional Deficiency Disease

Search GEO for disease gene expression data for Nutritional Deficiency Disease.

Pathways for Nutritional Deficiency Disease

GO Terms for Nutritional Deficiency Disease

Cellular components related to Nutritional Deficiency Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.89 TTR TF RBP4 LEP IL6 IGFBP3
2 endoplasmic reticulum lumen GO:0005788 9.76 TF IL6 IGFBP3 IGFBP1 GHRL CP
3 extracellular space GO:0005615 9.55 TTR TF RBP4 LEP IL6 IGFBP3
4 insulin-like growth factor ternary complex GO:0042567 9.32 IGFBP3 IGF1
5 insulin-like growth factor binding protein complex GO:0016942 9.26 IGFBP3 IGF1

Biological processes related to Nutritional Deficiency Disease according to GeneCards Suite gene sharing:

(show all 26)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.19 TTR LEP IL6 IGFBP1 IGF1 HAMP
2 negative regulation of apoptotic process GO:0043066 9.91 LHX3 LEP IL6 IGF1 GHRL EPO
3 post-translational protein modification GO:0043687 9.88 TF IL6 IGFBP3 IGFBP1 CP ALB
4 aging GO:0007568 9.86 IGFBP1 HAMP EPO BGLAP
5 response to hypoxia GO:0001666 9.85 MTHFR LEP EPO ADIPOQ
6 positive regulation of MAPK cascade GO:0043410 9.81 LEP IL6 IGFBP3 IGF1
7 response to nutrient GO:0007584 9.8 LEP EPO ADIPOQ
8 glucose homeostasis GO:0042593 9.8 RBP4 LEP IL6 ADIPOQ
9 negative regulation of tumor necrosis factor production GO:0032720 9.79 IGF1 GHRL ADIPOQ
10 response to glucocorticoid GO:0051384 9.78 IL6 BGLAP ADIPOQ
11 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.78 IL6 IGF1 CCK ADIPOQ
12 response to estrogen GO:0043627 9.77 GHRL EPO BGLAP
13 glucose metabolic process GO:0006006 9.76 LEP GHRL ADIPOQ
14 response to nutrient levels GO:0031667 9.76 LEP GHRL BGLAP ADIPOQ
15 cellular iron ion homeostasis GO:0006879 9.75 TF HAMP CP
16 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.73 LEP IL6 IGF1 EPO
17 iron ion homeostasis GO:0055072 9.7 TF HAMP CP
18 negative regulation of appetite GO:0032099 9.62 LEP CCK
19 adult feeding behavior GO:0008343 9.62 LEP GHRL
20 response to activity GO:0014823 9.62 LEP IL6 BGLAP ADIPOQ
21 regulation of insulin-like growth factor receptor signaling pathway GO:0043567 9.6 IGFBP3 IGFBP1
22 bone mineralization involved in bone maturation GO:0035630 9.57 LEP IGF1
23 response to ethanol GO:0045471 9.55 RBP4 LEP HAMP BGLAP ADIPOQ
24 negative regulation of lipid storage GO:0010888 9.43 LEP IL6 CRP
25 acute-phase response GO:0006953 9.26 IL6 HAMP EPO CRP
26 cellular protein metabolic process GO:0044267 9.23 TTR TF IL6 IGFBP3 IGFBP1 IGF1

Molecular functions related to Nutritional Deficiency Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptide hormone receptor binding GO:0051428 9.26 LEP CCK
2 hormone activity GO:0005179 9.23 TTR LEP IGF1 HAMP GHRL EPO
3 insulin-like growth factor II binding GO:0031995 9.16 IGFBP3 IGFBP1
4 copper ion binding GO:0005507 9.13 HAMP CP ALB

Sources for Nutritional Deficiency Disease

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
69 Tocris
71 UMLS via Orphanet
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