MCID: NTR005
MIFTS: 61

Nutritional Deficiency Disease

Categories: Metabolic diseases

Aliases & Classifications for Nutritional Deficiency Disease

MalaCards integrated aliases for Nutritional Deficiency Disease:

Name: Nutritional Deficiency Disease 12 15 17
Nutritional Disorder 54 17
Malnutrition 71 32
Carbamoyl-Phosphate Synthase I Deficiency Disease 71
Nutritional Deficiency 54
Deficiency Diseases 71
Nutrition Disorders 71
Nutrition 42

Classifications:



External Ids:

Disease Ontology 12 DOID:5113
MeSH 43 D003677
UMLS 71 C0011156 C0162429 C0751753 more

Summaries for Nutritional Deficiency Disease

MedlinePlus : 42 Food provides the energy and nutrients you need to be healthy. Nutrients include proteins, carbohydrates, fats, vitamins, minerals, and water. Healthy eating is not hard. The key is to Eat a variety of foods, including vegetables, fruits, and whole-grain products Eat lean meats, poultry, fish, beans, and low-fat dairy products Drink lots of water Limit salt, sugar, alcohol, saturated fat, and trans fat in your diet Saturated fats are usually fats that come from animals. Look for trans fat on the labels of processed foods, margarines, and shortenings. Centers for Disease Control and Prevention

MalaCards based summary : Nutritional Deficiency Disease, also known as nutritional disorder, is related to glossitis and hypothalamic obesity, and has symptoms including nausea and vomiting, abdominal pain and cachexia. An important gene associated with Nutritional Deficiency Disease is TTR (Transthyretin), and among its related pathways/superpathways are Glucose / Energy Metabolism and Circadian rythm related genes. The drugs Tramadol and Celecoxib have been mentioned in the context of this disorder. Affiliated tissues include breast, testes and liver, and related phenotypes are Reduced mammosphere formation and homeostasis/metabolism

Disease Ontology : 12 A nutrition disease that is characterized by deficiency of a nutritional element, such as a vitamin, mineral, carbohydrate, protein, fat, or general energy content.

Wikipedia : 74 Malnutrition is a condition that results from eating a diet in which one or more nutrients are either... more...

Related Diseases for Nutritional Deficiency Disease

Diseases related to Nutritional Deficiency Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 3049)
# Related Disease Score Top Affiliating Genes
1 glossitis 33.1 TTR IL6 CBLIF
2 hypothalamic obesity 32.9 LEP IGF1
3 folic acid deficiency anemia 32.7 EPO CRP CBLIF
4 protein-energy malnutrition 32.5 TTR TF RBP4 LEP IL6 IGF1
5 pyridoxine deficiency anemia 32.5 IGFBP1 CBLIF
6 esophageal cancer 32.5 MTHFR LEP IL6 IGFBP3 IGF1 CRP
7 iron deficiency anemia 32.4 TF IL6 GHRL EPO CRP CP
8 acute pancreatitis 31.9 IL6 CRP CCK ALB
9 cholestasis 31.9 IL6 CP CCK ALB
10 hyperuricemia 31.8 MTHFR LEP CRP ALB
11 hyperinsulinism 31.8 LEP IGFBP3 IGFBP1 IGF1 GHRL ADIPOQ
12 amyloidosis 31.7 TTR IL6 CRP ALB
13 porphyria 31.6 TF EPO CP ALB
14 ileus 31.6 IL6 GHRL CRP CCK
15 hyperglycemia 31.5 LEP IL6 IGF1 GHRL CCK ALB
16 metabolic acidosis 31.5 IL6 IGF1 BGLAP ALB
17 brain injury 31.5 IL6 IGF1 EPO
18 decubitus ulcer 31.5 TTR IL6 IGF1 CRP ALB
19 aspiration pneumonia 31.5 IL6 CRP ALB
20 conn's syndrome 31.5 LEP IGF1 GHRL BGLAP ADIPOQ
21 genetic obesity 31.5 LEP IGF1
22 hepatic encephalopathy 31.5 TTR IL6 ALB
23 thyroid gland disease 31.5 LEP IL6 IGF1 CRP ALB
24 intestinal obstruction 31.5 IL6 GHRL CRP ALB
25 uremia 31.4 LEP IL6 EPO CRP ALB
26 abdominal obesity-metabolic syndrome 1 31.4 LEP IGFBP1 GHRL ADIPOQ
27 myeloma, multiple 31.3 TTR IL6 IGF1 EPO CRP BGLAP
28 gastroesophageal reflux 31.3 IL6 GHRL CCK ADIPOQ
29 polycystic ovary syndrome 31.3 LEP IGFBP3 IGFBP1 IGF1 GHRL CRP
30 irritable bowel syndrome 31.3 IL6 GHRL CRP CCK
31 thrombophlebitis 31.3 MTHFR CRP ALB
32 arteriosclerosis 31.3 TTR IL6 GHRL CRP ADIPOQ
33 eclampsia 31.3 MTHFR IL6 ALB
34 gastroenteritis 31.3 IL6 CRP CP ALB
35 non-alcoholic steatohepatitis 31.3 IL6 IGF1 GHRL ALB ADIPOQ
36 intestinal disease 31.2 IL6 GHRL CRP ALB
37 pseudohypoparathyroidism 31.2 LEP IGF1 BGLAP
38 hyperphosphatemia 31.2 CRP BGLAP ALB
39 peripheral vascular disease 31.2 MTHFR IL6 EPO CRP ALB
40 osteoarthritis 31.2 IL6 IGF1 CRP BGLAP
41 abetalipoproteinemia 31.2 LEP IGF1 BGLAP
42 acute cystitis 31.2 IL6 CRP ALB
43 tetanus 31.2 IL6 IGF1 CRP ALB
44 proteasome-associated autoinflammatory syndrome 1 31.1 IL6 CRP ADIPOQ
45 lipid storage disease 31.1 LEP IL6 CRP ALB ADIPOQ
46 obstructive jaundice 31.1 TTR IL6 CRP ALB
47 gestational diabetes 31.1 RBP4 LEP IL6 IGFBP1 IGF1 CRP
48 urolithiasis 31.1 IL6 BGLAP ALB
49 bone resorption disease 31.1 LEP IL6 IGF1 CRP BGLAP ALB
50 arteries, anomalies of 31.1 LEP IL6 CRP ALB ADIPOQ

Comorbidity relations with Nutritional Deficiency Disease via Phenotypic Disease Network (PDN): (show all 12)


Active Peptic Ulcer Disease Acute Cystitis
Alzheimer Disease Decubitus Ulcer
Deficiency Anemia Familial Atrial Fibrillation
Heart Disease Iron Deficiency Anemia
Osteoporosis Protein-Energy Malnutrition
Schizophreniform Disorder Swallowing Disorders

Graphical network of the top 20 diseases related to Nutritional Deficiency Disease:



Diseases related to Nutritional Deficiency Disease

Symptoms & Phenotypes for Nutritional Deficiency Disease

UMLS symptoms related to Nutritional Deficiency Disease:


nausea and vomiting, abdominal pain, cachexia, constipation, diarrhea, abdominal symptom, decrease in appetite

GenomeRNAi Phenotypes related to Nutritional Deficiency Disease according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.17 ALB GHRL IGF1 IGFBP3 PMVK RBP4

MGI Mouse Phenotypes related to Nutritional Deficiency Disease:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.28 ADIPOQ ALB BGLAP CBLIF CCK CP
2 cellular MP:0005384 10.22 ADIPOQ ALB BGLAP CBLIF CP EPO
3 cardiovascular system MP:0005385 10.17 ADIPOQ ALB CP CRP EPO IGF1
4 adipose tissue MP:0005375 10.11 ADIPOQ BGLAP CP GHRL IGF1 IGFBP3
5 endocrine/exocrine gland MP:0005379 10.11 ADIPOQ ALB BGLAP CCK GHRL IGF1
6 immune system MP:0005387 10.03 ADIPOQ ALB BGLAP CBLIF CP CRP
7 liver/biliary system MP:0005370 9.85 ADIPOQ ALB CBLIF CP EPO IGFBP1
8 muscle MP:0005369 9.56 ADIPOQ ALB EPO IGF1 IGFBP3 IL6
9 renal/urinary system MP:0005367 9.23 ADIPOQ ALB CCK IGF1 IL6 LEP

Drugs & Therapeutics for Nutritional Deficiency Disease

Drugs for Nutritional Deficiency Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1164)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
2
Celecoxib Approved, Investigational Phase 4 169590-42-5 2662
3
Pentoxifylline Approved, Investigational Phase 4 6493-05-6 4740
4
Ferrous gluconate Approved Phase 4 299-29-6
5
parecoxib Approved Phase 4 198470-84-7
6
Alvimopan Approved, Investigational Phase 4 156053-89-3 5488548
7
Alogliptin Approved Phase 4 850649-61-5 11450633
8
Copper Approved, Investigational Phase 4 7440-50-8 27099
9
Phentermine Approved, Illicit Phase 4 122-09-8 4771
10
Zidovudine Approved Phase 4 30516-87-1 35370
11
Iodine Approved, Investigational Phase 4 7553-56-2 807
12
Naltrexone Approved, Investigational, Vet_approved Phase 4 16590-41-3 5360515
13
Bupropion Approved Phase 4 34911-55-2, 34841-39-9 444
14
Micafungin Approved, Investigational Phase 4 235114-32-6 477468 3081921
15
Lactitol Approved, Investigational Phase 4 585-88-6, 585-86-4 493591
16
Calcium carbonate Approved, Investigational Phase 4 471-34-1
17
Topiramate Approved Phase 4 97240-79-4 5284627
18
Piperazine Approved, Vet_approved Phase 4 110-85-0 4837
19
Furosemide Approved, Vet_approved Phase 4 54-31-9 3440
20
Ramipril Approved Phase 4 87333-19-5 5362129
21
Thrombin Approved, Investigational Phase 4
22
Ursodeoxycholic acid Approved, Investigational Phase 4 128-13-2 31401
23
Parathyroid hormone Approved, Investigational Phase 4 9002-64-6
24
Ampicillin Approved, Vet_approved Phase 4 69-53-4 6249
25
Amlodipine Approved Phase 4 88150-42-9 2162
26
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
27
Lisinopril Approved, Investigational Phase 4 76547-98-3, 83915-83-7 5362119
28
Ziprasidone Approved Phase 4 146939-27-7 60854
29
Propranolol Approved, Investigational Phase 4 525-66-6 4946
30
Tranexamic Acid Approved Phase 4 1197-18-8 5526
31
Anti-inhibitor coagulant complex Approved, Investigational Phase 4
32
Lumefantrine Approved Phase 4 82186-77-4 6437380
33
Artemether Approved Phase 4 71963-77-4 68911 9796294 119380
34
Halofantrine Approved Phase 4 69756-53-2 37393
35
Aripiprazole Approved, Investigational Phase 4 129722-12-9 60795
36
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 5311068 68602
37
Bisoprolol Approved Phase 4 66722-44-9 2405
38
Metoprolol Approved, Investigational Phase 4 37350-58-6, 51384-51-1 4171
39
Domperidone Approved, Investigational, Vet_approved Phase 4 57808-66-9 3151
40
Denosumab Approved Phase 4 615258-40-7
41 Apricot Approved Phase 4
42
Dextroamphetamine Approved, Illicit Phase 4 51-64-9 5826
43
Amphetamine Approved, Illicit, Investigational Phase 4 300-62-9 5826 3007
44
Medroxyprogesterone acetate Approved, Investigational Phase 4 71-58-9
45
Petrolatum Approved, Investigational Phase 4 8009-03-8
46
Polymyxin B Approved, Vet_approved Phase 4 1404-26-8
47
Sage Approved Phase 4
48
Clozapine Approved Phase 4 5786-21-0 2818
49
Simethicone Approved Phase 4 8050-81-5
50
Titanium dioxide Approved Phase 4 13463-67-7

Interventional clinical trials:

(show top 50) (show all 8195)
# Name Status NCT ID Phase Drugs
1 Influence of Immune Nutrition Diet on 90-Day Outcomes in Patients Undergoing Radical Cystectomy and Bladder Substitutions: A Randomized Controlled Trial Unknown status NCT03147586 Phase 4 Bio-tech and omega-3 plus;placebo
2 Immuno-enhanced Versus Standard Early Enteral Nutrition Use in Gastrointestinal Postoperative Patients Unknown status NCT01778166 Phase 4 Immuno-enhanced;Standard early enteral nutrition
3 The Clinical Use of Probiotics in the Uremia Patients Under Chronic Peritoneal Dialysis Unknown status NCT01076426 Phase 4 Pro-biotics
4 Fast-track Surgery Recovery Program With Early Jejunostomy Nutrition Protocol Minimizes Time to Adjuvant Chemotherapy in Patients Undergoing Laparoscopic Gastrectomy for Gastric Cancer Unknown status NCT01766765 Phase 4
5 Effect of Enteral Nutrition in the Outcome of Patients With Cardiovascular Surgery Unknown status NCT01432769 Phase 4
6 Effects of Nutritional Supplementation in Malnourished Patients in Stable COPD:a Randomised Controlled Trial Unknown status NCT02197871 Phase 4
7 Impact of Immunonutrition on the Patients With Cystic Fibrosis Unknown status NCT02048592 Phase 4
8 Randomized, Open Label, Controlled Clinical Trial of Egg Albumin-Based Protein Supplement Versus Renal Specific Oral Supplement in Hemodialysis Patients Unknown status NCT01981083 Phase 4
9 Folic Acid Supplementation as an Appetizer in Primary Malnourished Egyptian Infants and Children Unknown status NCT03040219 Phase 4 Folic Acid
10 Comparing Body Composition Measurements - Bioelectrical Impedance Analysis and Dual-energy X-ray Absorptiometry - in Chronic Heart Failure Unknown status NCT02686866 Phase 4
11 Microbial Invasion During Parenteral Nutrition in Surgical Infants Receiving Glutamine. Unknown status NCT00647036 Phase 4 Dipeptiven (L-glutamine- Lalanine)
12 The Effect of Nutritional Supplementation in Cancer Patients With no Clinical Signs of Malnutrition Unknown status NCT01894828 Phase 4
13 Multicenter Randomized Open-label Controlled Study to Investigate Treatment Response of IV Injectafer vs Oral Iron to Baseline Hepcidin Levels in Patients With Iron Deficiency Anemia Secondary to Inflammatory Bowel Disease or Gastric Bypass Unknown status NCT02086968 Phase 4 Injectafer;Ferrous Sulfate tablets
14 Study of Vitamin D2 Virus 1,25(OH)2-Vitamin D3 and Normal Protein Diet Virus Low Protein Diet in the Treatment of CKD-MBD and Malnutrition for Progressive CKD Patients Unknown status NCT02005302 Phase 4 1,25(OH)2 Vitamin D3;Vitamin D2
15 Randomized, Parallel Group, Clinical Trial Comparing Intravenous Iron Sucrose Versus Oral Ferrous Sulphate in the Treatment of Perioperative Iron Deficiency in Patients With Colo-Rectal Neoplasm and Iron Deficiency Anemia. Unknown status NCT00199277 Phase 4 i.v. iron sucrose;Oral iron
16 Comparative Study About the Impact of Two Oil Emulsions, One of Them Formulated With MCT, LCT, Olive Oil and Omega 3 Fatty Acids Versus Another One Formulated With MCT and LCT, Administered Intravenously on Severe Acute Pancreatitis Clinical Evolution Unknown status NCT01376817 Phase 4 Fat emulsion with MCT, LCT, olive oil and omega 3 fatty acids;Fat emulsion with MCT and LCT
17 Phase IV Study Comparing a Nutritional Anti-Inflammatory Treatment to Steroids for Pediatric Crohn's Disease - the Molecular Basis Unknown status NCT00265772 Phase 4 MODULEN IBD (R) (specific Enteral Nutrition);prednisolon
18 Hepatic Function and Bile Acid in Preterm Infants Receiving Parenteral Lipids Emulsion Unknown status NCT01786759 Phase 4 ClinOleic;Intralipid
19 Efficacy of Perioperative Application of Omega-3 Polyunsaturated Fatty Acids on Postoperative Immunization in Gastric Cancer Patients - A Prospective, Randomized Clinical Trial Unknown status NCT01910948 Phase 4 omega-3 polyunsaturated fatty acids
20 Effect of Enteral Genistein Supplementation on Inflammatory Cytokines, Morbidity and Mortality in Patients With Sepsis Unknown status NCT02796794 Phase 4
21 A Double Blinded, Randomized, Controlled Investigation of Taurolidine-citrate/Heparin Catheter Lock Solution Versus Heparin in Patients on Home Parenteral Nutrition With Previously Proven High Risk of Catheter Related Blood Stream Infections. Unknown status NCT01948245 Phase 4
22 A Prospective, Controlled, Randomized, Study Evaluating the Clinical Efficacy, Including Nutritional Status, Immune Function and Safety of Omegaven (w-3 Fish Oil) Supplemented Parenteral Nutrition in Subjects of SICU. Unknown status NCT00172198 Phase 4 Omegaven 10%
23 Efficiency and Tolerance of a Small-peptide Enteral Feeding Formula Compared to a Whole-protein Formula in the Critically Ill Patient : a Prospective Randomized Trial Unknown status NCT01833624 Phase 4
24 The Impact of the French National Program for Nutrition and Health Guidelines on Vascular Function Following a Standardised Breakfast:The Nutri-Vasc Study Unknown status NCT01579409 Phase 4
25 Evaluation of Family Intervention Program for the Treatment of Overweight or Obese Children (Nereu Program): Randomized Clinical Trial Unknown status NCT01878994 Phase 4
26 Heparin Versus Taurolidine to Bloodstream Infection Prevention Related in Central Venous Catheter in Children With Intestinal Failure Unknown status NCT02515201 Phase 4 Taurolidine;Heparin
27 Randomized Cross-Over Trial of Captafer® vs. Oral Iron Sulfate in the Treatment of Iron Deficiency Anemia in Patients With Inflammatory Bowel Disease Unknown status NCT02774057 Phase 4 Captafer®;Iron Sulfate
28 Oxepa in Multiple Trauma: Prospective, Randomized, Comparative, Double-blind, Controlled Clinical Study Unknown status NCT01099501 Phase 4
29 Antibiotic Prophylaxis for Percutaneous Endoscopic Gastrostomy (PEG) in Children: a Randomised Controlled Trial. Unknown status NCT01870167 Phase 4 co-amoxiclav
30 Effects of Pioglitazone on Body Composition,Insulin Sensitivity and Protein Metabolism in ESRD Non Diabetic Individuals Unknown status NCT01253928 Phase 4 Pioglitazone
31 Branched-chain Amino Acid (BCAA) on Progression of Advanced Liver Disease (BRAVE): Korean Nation-wide Multicenter Retrospective and Prospective Observational Cohort Study Unknown status NCT02837302 Phase 4 Livact
32 A Randomized, Controlled, Single-blind Study of Effects of Enteral Nutrition and Corticosteroid on Intestinal Flora in Induction Remission of Crohn Disease in Adult Unknown status NCT02056418 Phase 4 corticosteroid
33 The Effect of Immunonutrition on Outcome and Postoperative Recovery in Patients Undergoing Elective Surgical Repair of a Thoraco (Abdominal) Aneurysm Aorta Unknown status NCT00339053 Phase 4 Immunonutrition ( Impact)
34 Randomized Clinical Trial of Omega-3 Fatty Acid-supplemented Parenteral Nutrition Versus Standard Parenteral Nutrition in Patients Undergoing Major Laparoscopic Abdominal Surgery Unknown status NCT01819961 Phase 4 MCT/LCT and fish oil;MCT/LCT
35 Prevention and Control of Obesity in Primary School Children in Tehran Unknown status NCT02082080 Phase 4
36 Healthy Opportunities for Physical Activity and Nutrition (HOP'N) After-School Project Unknown status NCT01015599 Phase 4
37 Effects of Parenteral Nutrition With Different Lipid Emulsions in Preterm Infants Unknown status NCT01683162 Phase 4 ClinOleic;Lipofundin;Intralipid
38 Comparison of Two Strategies for Glycemic Control in Acute Ischemic Stroke Unknown status NCT00747279 Phase 4 Intensive insulin therapy
39 Treatment of Anemia in the 2nd Year of Life. Comparison of the Efficacy of Two Different Iron Preparations. Unknown status NCT00248716 Phase 4 Ferrous gluconate and iron polysaccharide complex
40 Providing Intravenous Paricalcitol Treatment to the Sick and Poor Chronic Hemodialysis Patients With Severe Secondary Hyperparathyroidism Resistant to Existing Vitamin D Analogs Unknown status NCT03023748 Phase 4 Intravenous Paricalcitol
41 Effectiveness of Iron Supplementation in the Second Year of Life for Prevention of Iron Deficiency Unknown status NCT00479102 Phase 4 Ferripel-3 - iron polysaccharide complex for prevention
42 Effect of COX-2 Selective Inhibitors on Postoperative Insulin Resistance, Tramadol PCA and Early Postoperative Enteral Nutrition in Patients After Gastrointestinal Laparoscopic Surgery Unknown status NCT01930318 Phase 4 parecoxib
43 Effects of Omega-3 Fatty Acids on Bone and Frailty Unknown status NCT00634686 Phase 4
44 Effect of Supplemental Intake of Omega-3 Polyunsaturated Fatty Acids on the Rate and Complexity of Spontaneously Occurring Ventricular and Supraventricular Arrhythmias in Patients With Implantable Cardioverter Defibrillator (ICD) - A Randomized Clinical Trial Unknown status NCT00290056 Phase 4 Eicosapentanoic acid (EPA) and Docosahexanoic acid (DHA).
45 Preoperative Parenteral Thiamine Supplementation in Patients Undergoing Heart Surgery - a Pilot Study Unknown status NCT01524315 Phase 4 Vitamin B1-ratiopharm;Placebo
46 A Randomized Controlled Trial Comparing SGC and Conventional Empiric Treatment for Glucose Control in Critically Ill Patients With Mechanical Ventilation in ICU Unknown status NCT02491346 Phase 4
47 Phase 4 Study of Mechanisms of Low Protein Diet Supplemented With Ketoanalogs on Reducing Proteinuria and Maintaining Nutritional Status in Type 2 Diabetic Nephropathy Unknown status NCT01300273 Phase 4
48 Randomized, Double-Blind, Placebo-Controlled Trial of Alvimopan in Major Spine Surgery Unknown status NCT02789111 Phase 4 Alvimopan;Placebo
49 The Orange-III Trial: Optimised Recovery With Movicol® Preoperatively Within an Enhanced Recovery Programme, a Randomised Controlled Trial Unknown status NCT01429779 Phase 4 Movicol
50 Randomized Placebo Controlled Trial of Postoperative Pain After Intravenous Vitamin C Injection for Arthroscopic Rotator Cuff Repair Unknown status NCT02992028 Phase 4 Intravenous Nutrition (Vitamins) injection;Intravenous Saline injection

Search NIH Clinical Center for Nutritional Deficiency Disease

Inferred drug relations via UMLS 71 / NDF-RT 50 :


Acetylcarnitine
ALBUMIN,EGG
Beef prepartion
borage oil
Calcium caseinate
Fiber
Levocarnitine
MANGANESE (AS GLYCEROPHOSPHATE)
MANGANESE AMINO ACID CHELATE
manganese chloride
manganese dioxide
MANGANESE GLUCONATE
manganese sulfate
Medium chain triglycerides
Selenious Acid
Selenium
selenium sulfide
Sodium Iodide
Sodium iodide I123
sodium selenate
TRIGLYCERYL DIISOSTEARATE

Genetic Tests for Nutritional Deficiency Disease

Anatomical Context for Nutritional Deficiency Disease

MalaCards organs/tissues related to Nutritional Deficiency Disease:

40
Breast, Testes, Liver, Heart, Bone, Kidney, Brain

Publications for Nutritional Deficiency Disease

Articles related to Nutritional Deficiency Disease:

(show top 50) (show all 780)
# Title Authors PMID Year
1
Nutrition in times of Covid-19, how to trust the deluge of scientific information. 42
32487876 2020
2
COVID-19: The Inflammation Link and the Role of Nutrition in Potential Mitigation. 42
32438620 2020
3
Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections. 42
32340216 2020
4
Acute polyneuropathy in critically ill patients. 54 61
2351777 1990
5
Dietary riboflavin deficiency induces ariboflavinosis and esophageal epithelial atrophy in association with modification of gut microbiota in rats. 61
32458157 2020
6
Insights into basic science: what basic science can teach us about iron homeostasis in trauma patients. 61
31876785 2020
7
Revisiting the pathobiology of scurvy: a review of the literature in the context of a challenging case. 61
32154584 2020
8
Iron in Health and Disease: An Update. 61
31520313 2020
9
OVERWEIGHT AND ASSOCIATED FACTORS IN CHILDREN AND ADOLESCENTS WITH PHENYLKETONURIA: A SYSTEMATIC REVIEW. 61
32159642 2020
10
Manganese in Plants: From Acquisition to Subcellular Allocation. 61
32273877 2020
11
Preliminary Studies on Biodegradable Zinc Oxide Nanoparticles Doped with Fe as a Potential Form of Iron Delivery to the Living Organism. 61
31823131 2019
12
Interaction between adipocytes and high-density lipoprotein:new insights into the mechanism of obesity-induced dyslipidemia and atherosclerosis. 61
31842884 2019
13
Micromotors for Active Delivery of Minerals toward the Treatment of Iron Deficiency Anemia. 61
31588746 2019
14
Cachexia/Protein energy wasting syndrome in CKD: Causation and treatment. 61
31286575 2019
15
The Analysis of Food Intake in Patients with Cirrhosis Waiting for Liver Transplantation: A Neglected Step in the Nutritional Assessment. 61
31618837 2019
16
Zinc biofortification of cereals-role of phosphorus and other impediments in alkaline calcareous soils. 61
30903431 2019
17
The effect of high-fat diet on the morphological properties of the forelimb musculature in hypertrophic myostatin null mice. 61
31198988 2019
18
Effect of Moringa Oleifera leaf powder supplementation on reducing anemia in children below two years in Kisarawe District, Tanzania. 61
31428346 2019
19
Iron Deficiency as a Therapeutic Target in Cardiovascular Disease. 61
31466321 2019
20
Isolation and identification of iron-chelating peptides from casein hydrolysates. 61
30993279 2019
21
The different tolerance to magnesium deficiency of two grapevine rootstocks relies on the ability to cope with oxidative stress. 61
30991946 2019
22
Glutamine Metabolism in Macrophages: A Novel Target for Obesity/Type 2 Diabetes. 61
30753258 2019
23
Behavioral, socio-environmental, educational and demographic correlates of excess body weight in Italian adolescents and young adults. 61
30718143 2019
24
Quercetin inhibits intestinal non-haem iron absorption by regulating iron metabolism genes in the tissues. 61
29594477 2019
25
Early Neuropathy Related to Oxaliplatin Treatment in Advanced and Recurrent Colorectal Cancer. 61
30842168 2019
26
The Frequency of Anemia and Underlying Factors among Iranian Pregnant Women from Provinces with Different Maternal Mortality Rate. 61
31205889 2019
27
Taste perception and oral microbiota are associated with obesity in children and adolescents. 61
31509575 2019
28
Pellagra, a re-emerging disease: a case report of a girl from a community ravaged by insurgency. 61
31692657 2019
29
Genotype Variation in Rice (Oryza sativa L.) Tolerance to Fe Toxicity Might Be Linked to Root Cell Wall Lignification. 61
31244872 2019
30
West Syndrome in an Infant With Vitamin B12 Deficiency Born to Autoantibodies Positive Mother. 61
31956646 2019
31
Obese rats are more vulnerable to inflammation, genotoxicity and oxidative stress induced by coal dust inhalation than non-obese rats. 61
30179764 2018
32
Effect of malting period on physicochemical properties, minerals, and phytic acid of finger millet (Eleusine coracana) flour varieties. 61
30349675 2018
33
Overweight and Obesity: A major concern for health in India. 61
30393804 2018
34
Circulating regulatory T cells (Treg), leptin and induction of proinflammatory activity in obese Labrador Retriever dogs. 61
30078586 2018
35
Boron: Functions and Approaches to Enhance Its Availability in Plants for Sustainable Agriculture. 61
29937514 2018
36
Regulation of yeast fatty acid desaturase in response to iron deficiency. 61
29627385 2018
37
Gastric Perforation as a complication of intragastric balloon. 61
29475822 2018
38
Importance of Serum Amino Acid Profile for Induction of Hepatic Steatosis under Protein Malnutrition. 61
29615653 2018
39
Nutritional Therapy in Gastrointestinal Cancers. 61
29413016 2018
40
Causes of Death in Chinese Patients with Multiple System Atrophy. 61
29392085 2018
41
Overnutrition: Does Complementary Feeding Play a Role? 61
30196296 2018
42
Oral manifestations of nutritional disorders. 61
28916025 2017
43
[Iron deficiency in ND-CKD: from diagnosis to treatment]. 61
28963827 2017
44
Prevalence of malnutrition and associated factors among hospitalized elderly patients in King Abdulaziz University Hospital, Jeddah, Saudi Arabia. 61
28673255 2017
45
Assessment of gross malnutrition among primary school children using body mass index as an assessment tool in abakaliki metropolis of Ebonyi State, South-East Nigeria. 61
28656923 2017
46
Adiponectin, Retinoic Acid Receptor Responder 2, and Peroxisome Proliferator-Activated Receptor-γ Coativator-1 Genes and the Risk for Obesity. 61
28947843 2017
47
Microbiota and Obesity. 61
28346926 2017
48
Genetic factors underlying boron toxicity tolerance in rice: genome-wide association study and transcriptomic analysis. 61
28204664 2017
49
A long-term retrospective study on rehabilitation of seabirds in Gran Canaria Island, Spain (2003-2013). 61
28475653 2017
50
Are Pediatricians Diagnosing Obese Children? 61
28331453 2017

Variations for Nutritional Deficiency Disease

Expression for Nutritional Deficiency Disease

Search GEO for disease gene expression data for Nutritional Deficiency Disease.

Pathways for Nutritional Deficiency Disease

GO Terms for Nutritional Deficiency Disease

Cellular components related to Nutritional Deficiency Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.89 TTR TF RBP4 LEP IL6 IGFBP3
2 endoplasmic reticulum lumen GO:0005788 9.76 TF IL6 IGFBP3 IGFBP1 GHRL CP
3 extracellular space GO:0005615 9.55 TTR TF RBP4 LEP IL6 IGFBP3
4 insulin-like growth factor ternary complex GO:0042567 9.32 IGFBP3 IGF1
5 insulin-like growth factor binding protein complex GO:0016942 9.26 IGFBP3 IGF1

Biological processes related to Nutritional Deficiency Disease according to GeneCards Suite gene sharing:

(show all 25)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.18 TTR LEP IL6 IGFBP1 IGF1 GHRL
2 response to hypoxia GO:0001666 9.81 MTHFR LEP EPO ADIPOQ
3 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.79 LEP IGF1 EPO
4 response to nutrient GO:0007584 9.77 LEP EPO ADIPOQ
5 positive regulation of MAPK cascade GO:0043410 9.76 LEP IL6 IGFBP3 IGF1
6 response to glucocorticoid GO:0051384 9.74 IL6 BGLAP ADIPOQ
7 response to estrogen GO:0043627 9.73 GHRL EPO BGLAP
8 response to ethanol GO:0045471 9.73 RBP4 LEP BGLAP ADIPOQ
9 post-translational protein modification GO:0043687 9.73 TF IL6 IGFBP3 IGFBP1 CP ALB
10 glucose metabolic process GO:0006006 9.72 LEP GHRL ADIPOQ
11 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.71 IL6 IGF1 CCK ADIPOQ
12 negative regulation of apoptotic process GO:0043066 9.7 LHX3 LEP IL6 IGF1 GHRL EPO
13 response to activity GO:0014823 9.67 LEP BGLAP ADIPOQ
14 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.67 LEP IL6 IGF1 EPO
15 acute-phase response GO:0006953 9.65 IL6 EPO CRP
16 positive regulation of insulin-like growth factor receptor signaling pathway GO:0043568 9.62 IGFBP3 IGF1
17 negative regulation of macrophage derived foam cell differentiation GO:0010745 9.62 CRP ADIPOQ
18 response to nutrient levels GO:0031667 9.62 LEP GHRL BGLAP ADIPOQ
19 positive regulation of immunoglobulin secretion GO:0051024 9.61 RBP4 IL6
20 adult feeding behavior GO:0008343 9.6 LEP GHRL
21 negative regulation of appetite GO:0032099 9.58 LEP CCK
22 regulation of insulin-like growth factor receptor signaling pathway GO:0043567 9.58 IGFBP3 IGFBP1
23 bone mineralization involved in bone maturation GO:0035630 9.54 LEP IGF1
24 cellular protein metabolic process GO:0044267 9.23 TTR TF IL6 IGFBP3 IGFBP1 IGF1
25 negative regulation of lipid storage GO:0010888 9.13 LEP IL6 CRP

Molecular functions related to Nutritional Deficiency Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 insulin-like growth factor I binding GO:0031994 9.26 IGFBP3 IGFBP1
2 hormone activity GO:0005179 9.17 TTR LEP IGF1 GHRL EPO CCK
3 peptide hormone receptor binding GO:0051428 9.16 LEP CCK
4 insulin-like growth factor II binding GO:0031995 8.96 IGFBP3 IGFBP1

Sources for Nutritional Deficiency Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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