MCID: NTR002
MIFTS: 20

Nutritional Optic Neuropathy

Categories: Eye diseases, Metabolic diseases, Neuronal diseases

Aliases & Classifications for Nutritional Optic Neuropathy

MalaCards integrated aliases for Nutritional Optic Neuropathy:

Name: Nutritional Optic Neuropathy 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:1209
ICD9CM 34 377.33
SNOMED-CT 67 82108004
ICD10 32 H46.2
UMLS 70 C0155302

Summaries for Nutritional Optic Neuropathy

Disease Ontology : 12 An optic neuritis that is characterized by nutritional deficiency causing optic nerve dysfunction, has symptom painless bilateral progressive decrease in visual acuity and color perception, and has material basis in nuritional deficits, especially of folate and vitamin B, which can be associated with restrictive diets and alcohol abuse.

MalaCards based summary : Nutritional Optic Neuropathy is related to optic nerve disease and toxic optic neuropathy, and has symptoms including painless bilateral progressive decrease in visual acuity An important gene associated with Nutritional Optic Neuropathy is RGL1 (Ral Guanine Nucleotide Dissociation Stimulator Like 1). Affiliated tissues include eye, and related phenotype is vision/eye.

Related Diseases for Nutritional Optic Neuropathy

Graphical network of the top 20 diseases related to Nutritional Optic Neuropathy:



Diseases related to Nutritional Optic Neuropathy

Symptoms & Phenotypes for Nutritional Optic Neuropathy

Symptoms:

12
  • painless bilateral progressive decrease in visual acuity

MGI Mouse Phenotypes related to Nutritional Optic Neuropathy:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 vision/eye MP:0005391 8.92 AQP4 KCNV2 OPA3 RGS9BP

Drugs & Therapeutics for Nutritional Optic Neuropathy

Search Clinical Trials , NIH Clinical Center for Nutritional Optic Neuropathy

Genetic Tests for Nutritional Optic Neuropathy

Anatomical Context for Nutritional Optic Neuropathy

MalaCards organs/tissues related to Nutritional Optic Neuropathy:

40
Eye

Publications for Nutritional Optic Neuropathy

Articles related to Nutritional Optic Neuropathy:

(show all 24)
# Title Authors PMID Year
1
Evaluation of the choroidal thickness and retinal nerve fiber layer and visual fields in morbid obesity: Does bariatric surgery affect retinal structure and function? 61
33463578 2021
2
Evaluation of the choroidal thickness and retinal nerve fiber layer, and visual field in morbid obesity: Does bariatric surgery affect retinal structure and function? 61
33318450 2020
3
Food Aversion Leading to Nutritional Optic Neuropathy in a Child With Severe Vitamin A Deficiency. 61
33136685 2020
4
Nutritional Optic Neuropathies: State of the Art and Emerging Evidences. 61
32878163 2020
5
Treatment and Outcomes in Nutritional Optic Neuropathy. 61
30729321 2019
6
Re: Nutritional optic neuropathy instead of tobacco-alcohol amblyopia. 61
29217037 2017
7
Nutritional optic neuropathy instead of tobacco-alcohol amblyopia. 61
28985817 2017
8
Bilateral normal tension glaucoma: Can this be nutritional? 61
28724826 2017
9
Nutritional Optic Neuropathy Caused by Copper Deficiency After Bariatric Surgery. 61
26828841 2016
10
Retinal Ganglion Cell Layer Analysis by Optical Coherence Tomography in Toxic and Nutritional Optic Neuropathy. 61
25724010 2015
11
Nutritional optic neuropathy in patients hospitalized for alcohol withdrawal. 61
25581662 2014
12
Nutritional optic neuropathy following bariatric surgery. 61
25562012 2014
13
Nutritional optic neuropathy. 61
25345287 2014
14
Low prevalence of bilateral (presumed nutritional) optic neuropathy as a cause of blindness in the Gambia. 61
23965687 2013
15
Tobacco-alcohol amblyopia: a diagnostic dilemma. 61
23477666 2013
16
Tobacco optic neuropathy (TON) - the historical and present concept of the disease. 61
20337605 2011
17
Toxic optic neuropathy. 61
12914684 2003
18
Optic neuropathy from folic acid deficiency without alcohol abuse. 61
11901292 2002
19
Acute vision loss resulting from complications of ethanol abuse. 61
9610037 1998
20
Clinical spectrum of Leber's hereditary optic neuropathy. 61
9292259 1997
21
Pattern- and flash-evoked potential changes in toxic (nutritional) optic neuropathy. 61
7054930 1982
22
Management of optic neuritis. 61
178061 1976
23
Nutritional optic neuropathy. 61
20997266 1946
24
Nutritional retrobulbar neuritis; nutritional optic neuropathy. 61
20995276 1946

Variations for Nutritional Optic Neuropathy

Expression for Nutritional Optic Neuropathy

Search GEO for disease gene expression data for Nutritional Optic Neuropathy.

Pathways for Nutritional Optic Neuropathy

GO Terms for Nutritional Optic Neuropathy

Biological processes related to Nutritional Optic Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 visual perception GO:0007601 8.96 RGS9BP OPA3
2 regulation of lipid metabolic process GO:0019216 8.62 RGL1 OPA3

Sources for Nutritional Optic Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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