MCID: OBS635
MIFTS: 24

Obsolete: Laryngeal Dyskinesia

Categories: Rare diseases

Aliases & Classifications for Obsolete: Laryngeal Dyskinesia

MalaCards integrated aliases for Obsolete: Laryngeal Dyskinesia:

Name: Obsolete: Laryngeal Dyskinesia 59
Spasmodic Dysphonia 59
Laryngeal Dystonia 59

Classifications:



External Ids:

Orphanet 59 ORPHA93961

Summaries for Obsolete: Laryngeal Dyskinesia

MalaCards based summary : Obsolete: Laryngeal Dyskinesia, also known as spasmodic dysphonia, is related to spasmodic dysphonia and spasmodic dystonia. The drugs Acetylcholine and Cholinergic Agents have been mentioned in the context of this disorder. Affiliated tissues include brain, cortex and testes.

Related Diseases for Obsolete: Laryngeal Dyskinesia

Diseases related to Obsolete: Laryngeal Dyskinesia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 106)
# Related Disease Score Top Affiliating Genes
1 spasmodic dysphonia 12.2
2 spasmodic dystonia 11.9
3 spinocerebellar ataxia 20 11.7
4 dystonia 6, torsion 11.6
5 dyt-tubb4a 11.6
6 dystonia 16 11.4
7 dystonia 10.9
8 tremor 10.4
9 movement disease 10.4
10 anxiety 10.3
11 mumps 10.3
12 essential tremor 10.3
13 head injury 10.3
14 focal dystonia 10.3
15 dysphagia 10.2
16 hemifacial spasm, familial 10.2
17 lymphatic malformation 5 10.2
18 autosomal dominant cerebellar ataxia 10.2
19 tic disorder 10.2
20 measles 10.2
21 hemifacial spasm 10.2
22 spasticity 10.2
23 stuttering 10.1
24 blepharospasm 10.1
25 amyotrophic lateral sclerosis 1 10.1
26 gastroesophageal reflux 10.1
27 multiple sclerosis 10.1
28 hand skill, relative 10.1
29 hemifacial atrophy, progressive 10.1
30 parkinson disease, late-onset 10.1
31 stiff-person syndrome 10.1
32 trigeminal neuralgia 10.1
33 sucrase-isomaltase deficiency, congenital 10.1
34 aging 10.1
35 myoclonic epilepsy associated with ragged-red fibers 10.1
36 spinocerebellar ataxia 12 10.1
37 dystonia 17, torsion, autosomal recessive 10.1
38 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.1
39 striatal degeneration, autosomal dominant 2 10.1
40 foodborne botulism 10.1
41 focal hand dystonia 10.1
42 aphasia 10.1
43 sensorineural hearing loss 10.1
44 amnestic disorder 10.1
45 bell's palsy 10.1
46 hypochondriasis 10.1
47 lagophthalmos 10.1
48 transient global amnesia 10.1
49 glossopharyngeal neuralgia 10.1
50 hypothyroidism 10.1

Graphical network of the top 20 diseases related to Obsolete: Laryngeal Dyskinesia:



Diseases related to Obsolete: Laryngeal Dyskinesia

Symptoms & Phenotypes for Obsolete: Laryngeal Dyskinesia

Drugs & Therapeutics for Obsolete: Laryngeal Dyskinesia

Drugs for Obsolete: Laryngeal Dyskinesia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 40)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved, Investigational Phase 4 51-84-3 187
2 Cholinergic Agents Phase 4
3 Acetylcholine Release Inhibitors Phase 4
4 Neurotransmitter Agents Phase 4
5 Botulinum Toxins Phase 4
6 abobotulinumtoxinA Phase 4
7 Neuromuscular Agents Phase 4
8 Peripheral Nervous System Agents Phase 4
9 Botulinum Toxins, Type A Phase 4
10 rimabotulinumtoxinB Phase 4
11
Ethanol Approved Phase 2, Phase 3 64-17-5 702
12
Sodium oxybate Approved Phase 2, Phase 3 502-85-2 5360545
13 Adjuvants, Anesthesia Phase 2, Phase 3
14 Anti-Infective Agents, Local Phase 2, Phase 3
15 Central Nervous System Depressants Phase 2, Phase 3
16 Anesthetics Phase 2, Phase 3
17 Anesthetics, General Phase 2, Phase 3
18 Anesthetics, Intravenous Phase 2, Phase 3
19 Anti-Infective Agents Phase 2, Phase 3
20
Guaifenesin Approved, Investigational, Vet_approved Phase 1 93-14-1 3516
21
Dextromethorphan Approved Phase 1 125-71-3 5360696 5362449
22
Lorazepam Approved Phase 1 846-49-1 3958
23 Antiemetics Phase 1
24 Gastrointestinal Agents Phase 1
25 GABA Agents Phase 1
26 Psychotropic Drugs Phase 1
27 Tranquilizing Agents Phase 1
28 Anti-Anxiety Agents Phase 1
29 Respiratory System Agents Phase 1
30 Chlorpheniramine, phenylpropanolamine drug combination Phase 1
31 Hypnotics and Sedatives Phase 1
32 Excitatory Amino Acid Antagonists Phase 1
33 GABA Modulators Phase 1
34 Excitatory Amino Acids Phase 1
35 Antitussive Agents Phase 1
36 Anticonvulsants Phase 1
37 Autonomic Agents Phase 1
38
Lidocaine Approved, Vet_approved 137-58-6 3676
39 Dihydroxyphenylalanine
40 incobotulinumtoxinA

Interventional clinical trials:

(show all 25)
# Name Status NCT ID Phase Drugs
1 An Open Label Evaluation of MIDI to Quantify Performance Change in Subjects With Musician's Dystonia After Treatment With Botulinum Toxin Type B (Myobloc ®). Completed NCT00208091 Phase 4 Botulinum toxin, type B
2 Treatment for Adductor Spasmodic Dysphonia by Type 2 Thyroplasty Using Titanium Bridges Completed NCT02528006 Phase 2, Phase 3
3 Central Mechanisms and Treatment Response of Sodium Oxybate in Spasmodic Dysphonia and Voice Tremor Recruiting NCT03292458 Phase 2, Phase 3 Sodium Oxybate
4 Voice Tremor in Spasmodic Dysphonia: Central Mechanisms and Treatment Response Completed NCT01961297 Phase 2 Sodium oxybate
5 Thalamic Deep Brain Stimulation for Spasmodic Dysphonia: A Prospective, Randomized, Double-Blinded, Sham-Controlled Trial Unknown status NCT02558634 Phase 1
6 The Effects of an NMDA-Receptor Antagonist in Idiopathic Voice Disorders Completed NCT00055549 Phase 1 Dextromethorphan;Lorazepam
7 Laryngeal Resistance in Abductor Spasmodic Dysphonia Completed NCT00015795 Phase 1
8 Repetitive Transcranial Magnetic Stimulation in Spasmodic Dysphonia Completed NCT02957942
9 Characteristics of Idiopathic Familial Voice Disorders Completed NCT00001552
10 Effects of Vocal Exercise Following Botox Injection on Voice Handicap and Communicative Participation for Adductor Spasmodic Dysphonia Completed NCT03349086
11 Sensory Function in Idiopathic Voice Disorders Completed NCT00001922
12 Role of Neurotransmission and Functional CNS Networks in Spasmodic Dysphonia and Other Focal Dystonias Completed NCT00713414
13 Functional Brain Mapping of Laryngeal Sensorimotor Control in Voice Disorders Completed NCT00066911
14 Imaging Genetics of Spasmodic Dysphonia Recruiting NCT03042975
15 Botox Drug Use Investigation (Spasmodic Dysphonia) Recruiting NCT03543150 BOTOX
16 Laryngeal Vibration as a Non-invasive Treatment for Spasmodic Dysphonia Recruiting NCT03746509
17 Natural History and Biospecimen Repository for Dystonia; Comprehensive Rating Tools for Cervical Dystonia; Validity & Reliability of Diagnostic Methods & Measures of Spasmodic Dysphonia Recruiting NCT01373424
18 A Training Protocol for the Use of Botulinum Toxin in the Treatment of Neurological Disorders Recruiting NCT00001208
19 Neuropathological Basis of Spasmodic Dysphonia and Related Voice Disorders Active, not recruiting NCT00118586
20 The Effect of Vocal Rest Versus Vocalization Following Xeomin® Injections in Spasmodic Dysphonia Enrolling by invitation NCT03129087
21 Brain Networks in Dystonia Enrolling by invitation NCT03042962
22 Role of Ultrasound in Diagnosis of Laryngeal Lesions Not yet recruiting NCT03450694
23 Effect of Vocal Exercise After Botulinum Toxin Injection for Spasmodic Dysphonia Terminated NCT00895063
24 Multimodal Studies of Language Production and Comprehension in Normal Volunteers and Patients With Neurologically-Based Language Impairments Terminated NCT00001308
25 Validity and Reliability of the Spasmodic Dysphonia Diagnosis and Assessment Procedure (SD-DAP) for Quantifying Symptom Change Withdrawn NCT02061943

Search NIH Clinical Center for Obsolete: Laryngeal Dyskinesia

Genetic Tests for Obsolete: Laryngeal Dyskinesia

Anatomical Context for Obsolete: Laryngeal Dyskinesia

MalaCards organs/tissues related to Obsolete: Laryngeal Dyskinesia:

41
Brain, Cortex, Testes, Prostate, Tongue

Publications for Obsolete: Laryngeal Dyskinesia

Articles related to Obsolete: Laryngeal Dyskinesia:

(show top 50) (show all 619)
# Title Authors PMID Year
1
Movement Disorders and Voice. 38
31076164 2019
2
Spasmodic dysphonia as a presenting symptom of spinocerebellar ataxia type 12. 38
31190316 2019
3
Spasmodic Dysphonia in Multiple Sclerosis Treatment With Botulin Toxin A: A Pilot Study. 38
29650331 2019
4
Laboratory Evaluation of Spasmodic Dysphonia. 38
31288958 2019
5
A separation of innate and learned vocal behaviors defines the symptomatology of spasmodic dysphonia. 38
30582159 2019
6
Common practices in botulinum toxin injection for spasmodic dysphonia treatment: A national survey. 38
30582627 2019
7
Adductor spasmodic dysphonia: Botulinum toxin a injections or laser thyroarytenoid myoneurectomy? A comparison from the patient perspective. 38
31169922 2019
8
In-Office Laryngology Injections. 38
30905566 2019
9
Atypical somatosensory-motor cortical response during vowel vocalization in spasmodic dysphonia. 38
30930193 2019
10
Decoding phonation with artificial intelligence (DeP AI): Proof of concept. 38
31236467 2019
11
Botulinum toxin-B injection into the lacrimal gland and posterior cricoarytenoid muscle for the treatment of epiphora and abductor spasmodic dysphonia secondary to Parkinson's disease. 38
29939826 2019
12
Geriatric Dysphonia: Etiological Analysis in a Rural Hospital in India. 38
31275834 2019
13
Laryngeal Botulinum Toxin Injection for Vocal Tremor: Utility of Concurrent Strap Muscle Injection. 38
30588631 2019
14
The extrinsic risk and its association with neural alterations in spasmodic dysphonia. 38
31153765 2019
15
Acoustic and Perceptual Analyses of Adductor Spasmodic Dysphonia in Mandarin-speaking Chinese. 38
29449062 2019
16
The Impact of Socioeconomic Status on Voice Outcomes in Patients With Spasmodic Dysphonia Treated With Botulinum Toxin Injections. 38
30614248 2019
17
Top-down alteration of functional connectivity within the sensorimotor network in focal dystonia. 38
30918091 2019
18
The Influence of Linguistic Demand on Symptom Expression in Adductor Spasmodic Dysphonia. 38
31047737 2019
19
Multidose Botulinum Toxin A for Intralaryngeal Injection: A Cost Analysis. 38
29307768 2019
20
Anatomical Course of the Thyroarytenoid Branch of the Recurrent Laryngeal Nerve. 38
30208213 2019
21
Validation of the OMNI vocal effort scale in the treatment of adductor spasmodic dysphonia. 38
30315575 2019
22
Reliability of High-speed Videoendoscopic Ratings of Essential Voice Tremor and Adductor Spasmodic Dysphonia. 38
29246397 2019
23
Reliability and Validity of Speech Evaluation in Adductor Spasmodic Dysphonia: Common Mistake and Statistical Issues. 38
29103608 2019
24
Bilateral Vocal Fold Medialization: A Treatment for Abductor Spasmodic Dysphonia. 38
29132808 2019
25
Reply to: "Reliability and Validity of Speech Evaluation in Adductor Spasmodic Dysphonia; Common Mistake and Statistical Issues" by Saori Yanagida. 38
29122419 2019
26
Defining differences in patient characteristics between spasmodic dysphonia and laryngeal tremor. 38
30426500 2019
27
Treatment of psychiatric disturbances in common hyperkinetic movement disorders. 38
30501439 2019
28
Clinical experience with patients with spasmodic dysphonia and primary Meige syndrome. 38
29716720 2019
29
Task-specificity in focal dystonia is shaped by aberrant diversity of a functional network kernel. 38
30264427 2018
30
OnabotulinumtoxinA for adductor spasmodic dysphonia (ADSD): Functional results and the role of dosage. 38
30315835 2018
31
Vibratory Onset of Adductor Spasmodic Dysphonia and Muscle Tension Dysphonia: A High-Speed Video Study✰. 38
30595236 2018
32
Effect of Artemisia herba-alba consumption during pregnancy on fertility, morphological and behaviors of mice offspring. 38
30118834 2018
33
Low Voice, Spasmodic Dysphonia, and Hand Dystonia as Clinical Clues for KMT2B-Associated Early-Onset Dystonia. 38
29913530 2018
34
Botulinum neurotoxin for the treatment of movement disorders. 38
30244558 2018
35
Reliability and Validity of Speech Evaluation in Adductor Spasmodic Dysphonia. 38
28802787 2018
36
Bilateral Posterior Cricoarytenoid Myoneurectomy for Abductor Spasmodic Dysphonia. 38
30174222 2018
37
Consensus-Based Attributes for Identifying Patients With Spasmodic Dysphonia and Other Voice Disorders. 38
29931028 2018
38
Comparison of Two Multiparameter Acoustic Indices of Dysphonia Severity: The Acoustic Voice Quality Index and Cepstral Spectral Index of Dysphonia. 38
28739333 2018
39
Socioeconomic Variables of Patients with Spasmodic Dysphonia: A Preliminary Study. 38
28927659 2018
40
Objective Indices of Perceived Vocal Strain. 38
30064717 2018
41
Anxiety and depression in spasmodic dysphonia patients. 38
30101219 2018
42
Connectivity profiles of the insular network for speech control in healthy individuals and patients with spasmodic dysphonia. 38
29520481 2018
43
Quality of Life and Voice Changes After a Single Injection in Patients With ADSD Over Time. 38
29884509 2018
44
Operative Procedure of Anterior Commissure for Type II Thyroplasty. 38
28687381 2018
45
In-office laryngeal procedures (IOLP) in Canada: current safety practices and procedural care. 38
29615125 2018
46
Outcome Measurement in the Treatment of Spasmodic Dysphonia: A Systematic Review of the Literature. 38
29655932 2018
47
Outcomes of Onabotulinum Toxin A Treatment for Adductor Spasmodic Dysphonia and Laryngeal Tremor. 38
29423509 2018
48
Spasmodic Dysphonia in Hereditary Spastic Paraplegia Type 7. 38
30746405 2018
49
Pharyngeal Dystonia Mimicking Spasmodic Dysphonia. 38
28651822 2018
50
Clinical Practice Guideline: Hoarseness (Dysphonia) (Update) Executive Summary. 38
29494316 2018

Variations for Obsolete: Laryngeal Dyskinesia

Expression for Obsolete: Laryngeal Dyskinesia

Search GEO for disease gene expression data for Obsolete: Laryngeal Dyskinesia.

Pathways for Obsolete: Laryngeal Dyskinesia

GO Terms for Obsolete: Laryngeal Dyskinesia

Sources for Obsolete: Laryngeal Dyskinesia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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