Obstructive Hydrocephalus disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: OBS004 MIFTS: 44	Obstructive Hydrocephalus Categories: Neuronal diseases
Genes Tissues Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Obstructive Hydrocephalus

MalaCards integrated aliases for Obstructive Hydrocephalus:

Name: Obstructive Hydrocephalus ¹² ⁵⁴ ¹⁵ ⁷⁰ ³²

Classifications:

MalaCards categories:
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

ICD10: ³²

Diseases of the nervous system

Other disorders of the nervous system

Hydrocephalus

Obstructive hydrocephalus

External Ids:

Disease Ontology ¹² DOID:14159

ICD9CM ³⁴ 331.4

MeSH ⁴⁴ D006849

NCIt ⁵⁰ C116347

SNOMED-CT ⁶⁷ 230746009

ICD10 ³² G91.1

UMLS ⁷⁰ C0549423

Sources

Summaries for Obstructive Hydrocephalus

MalaCards based summary : Obstructive Hydrocephalus is related to cellular ependymoma and subependymal giant cell astrocytoma. An important gene associated with Obstructive Hydrocephalus is FOXJ1 (Forkhead Box J1), and among its related pathways/superpathways are Neuroscience and Spinal Cord Injury. The drugs Cisplatin and Mesna have been mentioned in the context of this disorder. Affiliated tissues include pineal, brain and pituitary, and related phenotypes are behavior/neurological and growth/size/body region

Sources

Related Diseases for Obstructive Hydrocephalus

Diseases related to Obstructive Hydrocephalus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 442)

#	Related Disease	Score	Top Affiliating Genes
1	cellular ependymoma	31.8	SYP NF2 GFAP
2	subependymal giant cell astrocytoma	31.3	TSC1 SYP MTOR GFAP ENO2
3	intracranial hypertension	31.2	PRL AQP4 AQP1
4	chiari malformation	30.7	SYP GFAP AQP1
5	head injury	30.4	PRL ENO2
6	neurilemmoma of the fifth cranial nerve	30.3	NF2 NF1
7	syringomyelia	30.2	NF1 GFAP AQP4
8	hydrocephalus	30.2	SYP PRL MTOR MPDZ GFAP FOXJ1
9	pineoblastoma	30.2	SYP GFAP AFP
10	brain edema	30.0	GFAP AQP4 AQP1
11	pineocytoma	30.0	SYP GFAP ENO2
12	intracranial cysts	30.0	GFAP ENO2
13	optic nerve disease	29.8	NF1 GFAP AQP4 AQP1
14	traumatic brain injury	29.8	GFAP ENO2 AQP4
15	brain injury	29.8	GFAP ENO2 AQP4
16	status epilepticus	29.7	MTOR GFAP ENO2
17	acoustic neuroma	29.7	NF2 NF1 AQP4 AQP1
18	hemangioblastoma	29.7	SYP GFAP ENO2
19	cowden syndrome	29.7	TSC1 NF2 NF1 MTOR
20	hemangioma	29.6	TSC1 SYP MTOR ENO2
21	neurilemmoma	29.5	NF2 NF1 GFAP ENO2
22	meningioma, familial	29.5	SYP NF2 NF1 GFAP
23	pilocytic astrocytoma	29.5	SYP OLIG2 NF1 MTOR GFAP
24	benign ependymoma	29.5	TSC1 SYP NF2 NF1 MTOR GFAP
25	central neurocytoma	29.4	SYP OLIG2 GFAP ENO2
26	cerebral degeneration	29.4	SYP OLIG2 GFAP FOXJ1 AQP4 AQP1
27	pineal gland cancer	29.1	SYP OLIG2 GFAP ENO2 AFP
28	tuberous sclerosis	29.1	TSC1 SYP NF2 NF1 MTOR GFAP
29	brain cancer	28.5	SYP OLIG2 NF2 NF1 GFAP ENO2
30	ciliary dyskinesia, primary, 43	11.2
31	hydrocephalus due to congenital stenosis of aqueduct of sylvius	11.2
32	hydrocephalus, congenital, 1	11.2
33	congenital communicating hydrocephalus	11.1
34	congenital hydrocephalus	11.1
35	megalencephaly-capillary malformation-polymicrogyria syndrome	11.0
36	arteriovenous malformation	10.4
37	meningitis	10.4
38	communicating hydrocephalus	10.4
39	extraventricular neurocytoma	10.3	SYP GFAP
40	desmoplastic infantile ganglioglioma	10.3	SYP GFAP
41	lung combined type small cell carcinoma	10.3	SYP GFAP
42	aneurysm	10.3
43	non-gestational ovarian choriocarcinoma	10.3	PRL AFP
44	dysferlinopathy	10.3	AQP4 AQP1
45	angiocentric glioma	10.3	SYP GFAP
46	ocular motor apraxia	10.3
47	thymus sarcomatoid carcinoma	10.3	SYP AFP
48	ovarian mixed germ cell neoplasm	10.3	MTOR AFP
49	medullomyoblastoma	10.3	SYP GFAP
50	hepatic angiomyolipoma	10.3	MTOR AFP

Comorbidity relations with Obstructive Hydrocephalus via Phenotypic Disease Network (PDN): (show all 18)

Acute Cystitis	Alzheimer Disease
Brain Cancer	Brain Compression
Cerebellum Cancer	Cerebral Degeneration
Communicating Hydrocephalus	Decubitus Ulcer
Deficiency Anemia	Epilepsy, Focal, with Speech Disorder and with or Without Mental Retardation
Hypertension, Essential	Parkinson Disease, Late-Onset
Pineal Gland Cancer	Protein-Energy Malnutrition
Respiratory Failure	Schizophreniform Disorder
Swallowing Disorders	Transient Cerebral Ischemia

Graphical network of the top 20 diseases related to Obstructive Hydrocephalus:

Sources

Symptoms & Phenotypes for Obstructive Hydrocephalus

MGI Mouse Phenotypes related to Obstructive Hydrocephalus:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	behavior/neurological	MP:0005386	10.35	AFP AQP1 AQP4 DUSP16 ENO2 FOXJ1
2	growth/size/body region	MP:0005378	10.22	AQP1 AQP4 DUSP16 ENO2 FOXJ1 GFAP
3	cardiovascular system	MP:0005385	10.2	AQP1 AQP4 CCDC85C DUSP16 FOXJ1 GFAP
4	mortality/aging	MP:0010768	10.18	AFP AQP1 AQP4 CCDC85C DUSP16 FOXJ1
5	nervous system	MP:0003631	10.1	AQP1 AQP4 CCDC85C ENO2 FOXJ1 GFAP
6	endocrine/exocrine gland	MP:0005379	10.09	AFP AQP1 AQP4 MTOR NF1 NF2
7	neoplasm	MP:0002006	9.87	AFP NF1 NF2 OLIG2 PLG PRL
8	renal/urinary system	MP:0005367	9.7	AQP1 AQP4 MTOR NF1 NF2 PLG
9	respiratory system	MP:0005388	9.65	AQP1 AQP4 ENO2 FOXJ1 MTOR NF1
10	vision/eye	MP:0005391	9.28	AQP1 AQP4 GFAP MPDZ NF1 NF2

Sources

Drugs & Therapeutics for Obstructive Hydrocephalus

Drugs for Obstructive Hydrocephalus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Cisplatin

Approved

15663-27-1

84093 441203 2767

Synonyms:

(SP-4-1)-diamminedichloridoplatinum

(SP-4-1)-diamminedichloroplatinum

(SP-4-2)-diamminedichloridoplatinum

(SP-4-2)-diamminedichloroplatinum

Abiplatin

Biocisplatinum

Briplatin

CACP

Carboquone

CDDP

CHEBI:35852

CID441203

Cis Pt II

cis-[PtCl2(NH3)2]

cis-DDP

Cis-DDP

Cis-Diaminedichloroplatinum

cis-diamminedichloridoplatinum(II)

cis-Diamminedichloroplatinum

Cis-Diamminedichloroplatinum

cis-diamminedichloroplatinum(II)

cis-Dichlorodiammineplatinum(II)

Cismaplat

Cisplatin

Cisplatine

cisplatino

Cisplatino

Cisplatinum

Cisplatyl

Citoplationo

CPD0-1392

CPDC

CPDD

DB00515

DDP

DDPT

Diamminedichloroplatinum

EU-0100918

Lederplatin

nchembio773-comp1

Neoplatin

Peyrone's chloride

Peyrone's salt

Plastin

Platamine

Platiblastin

Platidiam

Platinex

Platinol

Platinol-AQ

Platinoxan

Platinum Ammine Chloride

Platinum Ammonium Chloride

Platinum Diamine Dichloride

Randa

trans-DDP

Trans-DDP

Trans-Diaminedichloroplatinum

trans-diamminedichloridoplatinum(II)

Trans-Diamminedichloroplatinum

Trans-Dichlorodiammine Platinum

Trans-Platinumdiammine Dichloride

Mesna

Approved, Investigational

3375-50-6

598

Synonyms:

1-THIOETHANEsulfonate

1-THIOETHANEsulfonIC ACID

1-THIOETHANEsulphonate

1-THIOETHANEsulphonic acid

2 Mercaptoethanesulfonate

2-Mercaptoethane

2-Mercaptoethanesulfonate

2-mercaptoethanesulfonic acid

2-Mercaptoethanesulfonic acid

2-Mercaptoethanesulphonate

2-Mercaptoethanesulphonate, sodium

2-mercaptoethanesulphonic acid

2-Mercaptoethanesulphonic acid

2-mercaptoethylsulfonate

2-Mercaptoethylsulfonate

2-Mercaptoethylsulfonic acid

2-Mercaptoethylsulphonate

2-Mercaptoethylsulphonic acid

2-sulfanylethylsulfonate

2-Sulfanylethylsulfonate

2-Sulfanylethylsulfonic acid

2-Sulphanylethylsulphonate

2-Sulphanylethylsulphonic acid

ASTA D 7093

ASTA medica brand OF mesna

ASTAD 7093

ASTA-D 7093

beta-Mercaptoethanesulfonate

beta-Mercaptoethanesulfonic acid

beta-Mercaptoethanesulphonate

beta-Mercaptoethanesulphonic acid

b-Mercaptoethanesulfonate

b-Mercaptoethanesulfonic acid

b-Mercaptoethanesulphonate

b-Mercaptoethanesulphonic acid

Bristol myers squibb brand OF mesna

Bristol-myers squibb brand OF mesna

Cell pharm brand OF mesna

Coenzima m

Coenzima M

Coenzym m

Coenzym M

Coenzyme m

CoM

HS-CoM

Kendrick brand OF mesna

Mesna

MESNA cell

Mesna kendrick brand

Mesna sanfer brand

MESNA-cell

Mesnex

Mesnum

Mistabron

Mistabronco

Mitexan

Mucofluid

reduced coenzyme M

Reduced coenzyme m

reduced CoM

Reduced com

Sanfer brand OF mesna

Sodium 2-mercaptoethanesulphonate

UCB brand OF mesna

Uromitexan

Ziken

Β-mercaptoethanesulfonate

β-mercaptoethanesulfonic acid

Β-mercaptoethanesulfonic acid

Β-mercaptoethanesulphonate

Β-mercaptoethanesulphonic acid

Magnesium Sulfate

Approved, Investigational, Vet_approved

7487-88-9

24083

Synonyms:

(C10-C16) Alkylalcohol sulfuric acid, magnesium salt

00627_FLUKA

10028-26-9

10034-99-8 (heptahydrate)

13143_RIEDEL

13143_SIAL

139939-75-6

18939-43-0

203726_ALDRICH

208094_SIAL

34276_FLUKA

34276_RIEDEL

38146_FLUKA

38146_RIEDEL

63126_FLUKA

63136_FLUKA

63136_SIAL

63139_FLUKA

63139_SIAL

68081-97-0

7487-88-9

AC1L2N76

AC1LAX36

AC1Q1U66

AI3-02029

Bitter salt

C10-C16 Alkyl alcohol sulfuric acid magnesium salt

Caswell No. 534

CCRIS 8411

CHEBI:32599

CID24083

CPD0-2390

D008278

DB00653

EINECS 231-298-2

EINECS 233-073-4

EINECS 242-691-3

EINECS 268-365-0

EPA Pesticide Chemical Code 050503

Epsom salt

Hair salt

Heptahydrate Magnesium Sulfate

HSDB 664

Kieserite [as monohydrate]

LS-88605

M2643_SIGMA

M3409_SIGMA

M7506_SIAL

M8150_SIGMA

Magnesium bisulfate

Magnesium hydrogensulphate

MAGNESIUM SULFATE

Magnesium sulfate (1:1)

Magnesium sulfate anhydrous

Magnesium sulfate dried

Magnesium sulfate hexahydrate

Magnesium sulfate in dextrose 5% in plastic container

Magnesium Sulfate In Plastic Container

Magnesium sulfate solution

Magnesium Sulfate, Heptahydrate

Magnesium sulphate

Magnesium Sulphate Hydrate

magnesium(2+) ion sulfate

magnesium(II) sulfate

Magnesium(II) sulfate

Magnesiumsulfat

MgSO4

MolPort-003-925-000

NSC 146179

OT-S

OT-S (drying agent)

Sal amarum

Sal Angalis

Sal anglicum

Sal catharticum

Sal De sedlitz

Sal seidlitense

Salts of england

SDA 15-062-07

Sel d'angleterre

Sulfate, Magnesium

Sulfuric acid magnesium salt

Sulfuric acid magnesium salt (1:1)

Sulfuric acid magnesium salt (VAN)

Sulfuric acid, C10-16 alkyl ester, magnesium salt

Sulfuric acid, magnesium salt

Sulfuric acid, magnesium salt (1:1)

Sulfuric acid, mono-C10-16-alkyl esters, magnesium salts

Tomix OT

UNII-DE08037SAB

UNII-ML30MJ2U7I

Vincristine

Approved, Investigational

2068-78-2, 57-22-7

5978

Synonyms:

(+)-Vincristine

22-Oxovincaleukoblastin

22-oxo-Vincaleukoblastine

22-Oxovincaleukoblastine

28379-27-3

57-22-7

AC1L1LJC

C07204

C46H56N4O10

CCRIS 5763

Cellcristin

CHEBI:28445

CID5978

Citomid

D08679

DB00541

EINECS 200-318-1

Farmistin

HMS2090E19

HSDB 3199

Indole alkaloid

LCR

Leucristine

Leurocristine

Lilly 37231 (1:1 sulfate salt)

Liposomal Vincristine

LS-228

Marqibo

NCGC00163700-01

NCI60_026703

NCI-C04864

NSC-67574

Onco TCS

Oncovin

Oncovin (1:1 sulfate salt)

Oncovine

Onkocristin

PFS, Vincasar

Sulfate, vincristine

Tecnocris

Tecnocris (TN)

UNII-5J49Q6B70F

VCR

VIN

Vincaleukoblastine, 22-oxo- 22-Oxovincaleukoblastine

Vincasar

Vincasar (1:1 sulfate salt)

Vincasar PFS

Vincrex

Vincrex (1:1 sulfate salt)

Vincristin

Vincristin bristol

Vincristin medac

Vincristina

Vincristina [DCIT]

vincristine

Vincristine

Vincristine (INN)

Vincristine [INN:BAN]

Vincristine sulfate

Vincristine Sulfate

Vincristine Sulfate PFS

Vincristinum

Vincristinum [INN-Latin]

Vincrisul

Vincrstine

Vincrystine

Vinkristin

Vintec

Z-D-Val-lys(Z)-OH

Z-D-Val-Lys(Z)-OH

Mannitol

Approved, Investigational

69-65-8

453 6251

Synonyms:

(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexaol

(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol

(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol

(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexol

(L)-Mannitol

1,2,3,4,5,6-Hexanehexol

123897-58-5

133-43-7

15719_ALDRICH

15719_RIEDEL

33440_RIEDEL

33440_SIGMA

36413-61-3

4-01-00-02841 (Beilstein Handbook Reference)

5149-40-6

63559_FLUKA

63559_SIGMA

63560_FLUKA

63565_FLUKA

63565_SIGMA

69-65-8

75398-80-0

85085-15-0

87-78-5

AB1002081

AC-12776

AC1L1M49

AC1Q28E5

AI3-19511

Ambap69-65-8

AR-1J3861

bmse000099

BRN 1721898

Bronchitol

C00392

C6H14O6

CCRIS 369

CHEBI:16899

CHEMBL689

CID6251

Cordycepate

Cordycepic acid

cpd without stereochemical designation

D-(-)-Mannitol

D00062

D008353

Diosmol

DL-Mannitol

D-mannite

D-mannitol

D-Mannitol

D-Mannitol (JP15)

Dulcite

e 421

e421

e-421

ED1D1E61-FEFB-430A-AFDC-D1F4A957FC3D

EINECS 200-711-8

EINECS 201-770-2

Hexahydroxyhexane

Hexanhexol

HSDB 714

Invenex

Isotol

LS-1588

LS-89250

M0044

M1902_SIGMA

M4125_SIAL

M8429_SIAL

M9546_SIAL

M9647_SIAL

Manicol

manita

Manitol

Maniton S

Maniton-S

Manna sugar

Manna Sugar

Mannazucker

Mannidex

Mannidex 16700

Mannigen

Mannistol

Mannit

Mannit p

Mannite

mannitol

Mannitol

Mannitol (USP)

Mannitol (VAN)

Mannitol [USAN]

Mannitol 10%

Mannitol 10% In Plastic Container

MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER

Mannitol 15%

Mannitol 15% In Plastic Container

MANNITOL 15% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.45%

Mannitol 20%

Mannitol 20% In Plastic Container

MANNITOL 25%

Mannitol 5%

Mannitol 5% In Plastic Container

MANNITOL 5% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.12%

Mannitolum

Mannogem 2080

Marine crystal

Marine Crystal

MLS001335977

MLS001335978

MolPort-003-927-039

MTL

Mushroom sugar

NCGC00164246-01

NCI-C50362

NSC 407017

NSC 9256

Osmitrol

Osmitrol (TN)

Osmitrol 10% In Water

OSMITROL 10% IN WATER IN PLASTIC CONTAINER

Osmitrol 15% In Water

OSMITROL 15% IN WATER IN PLASTIC CONTAINER

Osmitrol 20% In Water

OSMITROL 20% IN WATER IN PLASTIC CONTAINER

Osmitrol 5% In Water

OSMITROL 5% IN WATER IN PLASTIC CONTAINER

Osmofundin

Osmosal

Resectisol

Resectisol In Plastic Container

SDM No. 35

SMR000857324

Sorbitol-Mannitol

SORBITOL-MANNITOL IN PLASTIC CONTAINER

TL806434

Tobrex

UNII-3OWL53L36A

ZINC02041302

Etoposide

Approved

33419-42-0

36462

Synonyms:

(−)-etoposide

(-)-Etoposide

121471-01-0

136598-18-0

201594-04-9

33419-42-0

35317-32-9

4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-b-D-glucopyranoside)

4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)

4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-β-D-glucopyranoside)

4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside)

4'-Demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside

4-Demethylepipodophyllotoxin b-D-ethylideneglucoside

4-Demethylepipodophyllotoxin beta-D-ethylideneglucoside

4'-Demethylepipodophyllotoxin ethylidene-.beta.-D-glucoside

4-demethylepipodophyllotoxin β-D-ethylideneglucoside

4-Demethylepipodophyllotoxin β-D-ethylideneglucoside

4-Demethylepipodophyllotoxin-.beta.-D-ethylideneglucoside

4'-O-Demethyl-1-O-(4,6-O-ethylidene-beta-D-glucopyranosyl)epipodophyllotoxin

51854-34-3

76576-58-4

9-((4,6-O-Ethylidine-b-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-D)-1,3-dioxol-6(5ah)-one

9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-one

9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-D)-1,3-dioxol-6(5ah)-one

9-((4,6-O-Ethylidine-β-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-D)-1,3-dioxol-6(5ah)-one

AB00438905

AC1L1FN8

AC1L1VT3

AC1L6246

AC1NR4OG

AC1O4WGG

AC1O7M1N

AC1Q47JJ

alpha-D-Glucopyranosyl isomer etoposide

Ambap33419-42-0

Baxter brand OF etoposide

Baxter oncology brand OF etoposide

Bio1_000489

Bio1_000978

Bio1_001467

BPBio1_000673

BRD-K37798499-001-02-5

Bristol myers brand OF etoposide

Bristol myers squibb brand OF etoposide

Bristol-myers brand OF etoposide

Bristol-myers squibb brand OF etoposide

BSPBio_000611

C01576

CCRIS 2392

Celltop

CHEBI:4911

CHEBI:588795

CHEMBL44657

CID11758093

CID284997

CID3310

CID36462

CID5284558

CID6419930

CID6610299

CPD000112002

D00125

DB00773

DEMETHY-EPIPODOPHYLLOTOXIN,ETHYLIDENE GLUCOSIDE,

Demethyl epipodophyllotoxin ethylidine glucoside

Demethyl Epipodophyllotoxin Ethylidine Glucoside

Demethyl-epiodophyllotoxin ethylidene glucoside

Demethylepipodophyllotoxin-beta-D-ethylideneglucoside

E0675

E1383_SIGMA

EINECS 251-509-1

Epipodophyllotoxin VP-16213

Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-.beta.-D-glucopyranoside

Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside

Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside (8CI)

Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-.beta.-D-glucopyranoside)

Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-beta-D-glucopyranoside)

Eposide

Eposin

Eposin, Vepesid, VP-16, Toposar, Etoposide

Eto gry

Eto-gry

Etomedac

ETOP

Etopol

Etopophos

Etopophos (phosphate salt)

Etopos

etoposide

Etoposide

Etoposide (JP15/USP/INN)

Etoposide (VP16)

Etoposide [USAN:INN:BAN:JAN]

Etoposide pierre fabre

Etoposide teva

Etoposide, (5a alpha)-isomer

Etoposide, (5a alpha,9 alpha)-isomer

Etoposide, (5S)-isomer

Etoposide, alpha D glucopyranosyl isomer

Etoposide, alpha-D-glucopyranosyl isomer

Etoposido

Etoposido [INN-Spanish]

Etoposido ferrer farma

Etoposidum

Etoposidum [INN-Latin]

Etosid

Exitop

Ferrer brand OF etoposide

Gry brand OF etoposide

HMS1569O13

HMS2052N05

HMS2089F14

HSDB 6517

I06-0248

KBioSS_002410

Lastet

Lemery brand OF etoposide

LS-1214

Medac brand OF etoposide

MLS000049957

MLS001074951

MLS001424283

MLS002153463

MLS002207239

MLS002222184

MolPort-003-983-431

MolPort-004-905-001

MolPort-004-955-161

NCGC00025056-02

NChemBio.2007.10-comp19

nchembio.573-comp8

nchembio873-comp2

NK 171

Novartis brand OF etoposide

NSC 141540

NSC141540

NSC-141540

Onkoposid

Onkoworks brand OF etoposide

Pharmachemie brand OF etoposide

Pierre fabre brand OF etoposide

Prasfarma brand OF etoposide

Prestwick_211

Prestwick0_000396

Prestwick1_000396

Prestwick2_000396

Prestwick3_000396

Riboposid

Ribosepharm brand OF etoposide

S1225_Selleck

SAM001246880

Sanfer brand OF etoposide

SMR000112002

SPBio_002532

ST056353

Tedec meiji brand OF etoposide

Teva brand OF etoposide

Teva, etoposide

Toposar

trans-Etoposide

UNII-6PLQ3CP4P3

Vepesid

VePesid

VePESID (TN)

Vepesid J

Vepeside

Vépéside sandoz

Vépéside-sandoz

VP 16

VP 16 (pharmaceutical)

VP 16213

VP 16-213

VP-16

VP-16-213

ZINC03830818

ZINC03938684

Zuyeyidal

Cyclophosphamide

Approved, Investigational

50-18-0, 6055-19-2

2907

Synonyms:

(-)-Cyclophosphamide

(+-)-Cyclophosphamide

(+,-)-2-(Bis(2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide monohydrate

(RS)-Cyclophosphamide

1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine

1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin

2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide

4-Hydroxy-cyclophosphan-mamophosphatide

50-18-0

60007-95-6

6055-19-2 (monohydrate)

75526-90-8

AC1L1EQQ

AI3-26198

Anhydrous cyclophosphamide

Anhydrous, cyclophosphamide

ASTA

Asta B 518

ASTA B518

B 518

B-518

bis(2-Chloroethyl)phosphami de cyclic propanolamide

bis(2-Chloroethyl)phosphamide cyclic propanolamide ester

Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester

BRN 0011744

BSPBio_002099

C 0768

C07888

C7H15Cl2N2O2P

CB 4564

CB-4564

CCRIS 188

CHEBI:4027

CHEMBL32520

CHEMBL88

Ciclofosfamida

Ciclofosfamida [INN-Spanish]

Ciclofosfamide

Ciclophosphamide

Ciclophosphamide [INN]

CID2907

Clafen

Claphene

CPA

CTX

Cycloblastin

Cyclophosphamid

cyclophosphamide

Cyclophosphamide

Cyclophosphamide (anhydrous form)

Cyclophosphamide (anhydrous)

Cyclophosphamide (INN)

Cyclophosphamide (TN)

Cyclophosphamide anhydrous

Cyclophosphamide monohydrate

Cyclophosphamide Monohydrate

Cyclophosphamide Sterile

Cyclophosphamide, (+-)-Isomer

Cyclophosphamide, (R)-isomer

Cyclophosphamide, (S)-isomer

Cyclophosphamides

Cyclophosphamidum

Cyclophosphamidum [INN-Latin]

Cyclophosphan

Cyclophosphane

Cyclophosphanum

Cyclophosphoramide

Cyclostin

Cyklofosfamid

Cyklofosfamid [Czech]

Cytophosphan

Cytophosphane

Cytoxan

Cytoxan (TN)

Cytoxan Lyoph

D,L-Cyclophosphamide

D07760

DB00531

DivK1c_000246

EINECS 200-015-4

Endoxan

Endoxan R

Endoxana

Endoxanal

Endoxan-Asta

Endoxane

Enduxan

EU-0100238

Genoxal

Hexadrin

HMS2090A12

HSDB 3047

IDI1_000246

KBio1_000246

KBio2_001338

KBio2_003906

KBio2_006474

KBio3_001319

KBioGR_000888

KBioSS_001338

Lopac0_000238

Lopac-C-0768

LS-1302

LS-99787

Lyophilized Cytoxan

Mitoxan

MolPort-001-783-420

Monohydrate, cyclophosphamide

N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide

N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

NCGC00015209-01

NCGC00015209-03

NCGC00015209-06

NCGC00091741-02

NCGC00091741-03

NCI60_002097

NCI-C04900

Neosar

NINDS_000246

NSC 26271

NSC26271

NSC-26271

NSC273033

NSC273034

Occupation, cyclophosphamide exposure

Procytox

RCRA waste no. U058

Rcra waste number U058

Rcra Waste Number U058

Revimmune

S1217_Selleck

Semdoxan

Sendoxan

Senduxan

SK 20501

SPBio_001071

Spectrum_000858

Spectrum2_001146

Spectrum3_000370

Spectrum4_000304

Spectrum5_000795

STK177249

STOCK2S-91217

UNII-6UXW23996M

WLN: T6MPOTJ BO BN2G2G

Zyklophosphamid

Zyklophosphamid [German]

Vitamin A

Approved, Nutraceutical, Vet_approved

68-26-8, 11103-57-4

445354

Synonyms:

(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol

(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol

(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol

(all-e)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol

(all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol

.alpha.lin

.alpha.sterol

.beta.-Retinol

[11,12-3H]-Retinol

11103-57-4

11-cis-Retinol

13123-33-6

1341-18-0

1406-67-3

17104-91-5

1rbp

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclchexen-1-yl)-2,4,6,8-nonatetraen-1-ol

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonate-traen-1-ol

3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol, (all-E)-Isomer

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol, (all-e)-isomer

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-2,4,6,8-nonatetraen-1-ol

4-06-00-04133 (Beilstein Handbook Reference)

53637-36-8

5979-23-7

68-26-8

95144_FLUKA

95144_SIGMA

95146_FLUKA

95146_SIGMA

AC-11701

AC1L9HU3

AC1Q7BU9

ACON

Afaxin

Agiolan

Agoncal

Alcohol 9,13-dimethyl-7-(1,1,5-trimethyl-6-cyclohexen-5-yl)-7,9,11,13-nonatetraen-15-ol

Alcovit A

alin

all trans Retinol

All Trans Retinol

All-trans retinol

ALL-TRANS RETINOL (SEE ALSO RETINOID PROJECT 1)

all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol

all-trans-retinol

all-trans-Retinol

all-trans-retinyl alcohol

all-trans-Retinyl alcohol

all-trans-Vitamin A

all-trans-vitamin A alcohol

all-trans-Vitamin a alcohol

all-trans-Vitamin A alcohol

all-trans-Vitamin A1

Alphalin

Alphasterol

A-Mulsal

Anatola

Anatola A

Anti-infective vitamin

Antixerophthalmic vitamin

Antixerophthalmisches Vitamin

Aoral

Apexol

Apostavit

Aquasol a

Aquasol A Parenteral

Aquasynth

AR-1L3057

A-Sol

Atars

ATAV

Avibon

A-Vi-Pel

Avita

A-Vitan

Avitol

Axerol

Axerophthol

Axerophtholum

Bentavit A

beta-Retinol

BIDD:PXR0102

Biosterol

b-Retinol

BRN 0403040

C00473

C17276

C20H30O

CCRIS 5444

CHEBI:17336

CHEMBL986

Chocola a

Chocola A

CID445354

Cylasphere

D014801

D06543

DB00162

Del-VI-A

Disatabs Tabs

Dofsol

Dohyfral A

EINECS 200-683-7

EINECS 234-328-2

Epiteliol

Hi-A-Vita

HMS1921B04

HMS2092L13

HMS501I08

Homagenets Aoral

Homagenets aorl

HSDB 815

Hydrovit A

IDI1_000486

Lard Factor

LMPR01090001

LPK

LS-1578

M.V.C. 9+3

M.V.I.-12

MLS001066379

MLS001074751

MolPort-001-785-962

Mvc Plus

Myvpack

NCGC00091784-01

NCGC00091784-02

NCGC00091784-03

NCGC00091784-04

NCGC00091784-05

NCGC00091784-06

Nio-A-Let

NSC 122759

NSC122759

Oleovitamin A

Ophthalamin

Plivit A

Prepalin

R7632_SIGMA

Retin-11,12-t2-ol (9CI)

retinol

Retinol

Retinol [INN:BAN]

Retinol solution

Retinol-(cellular-retinol-binding-protein)

Retinol, all-trans- (8CI)

Retinolo

Retinolo [DCIT]

Retinolum

Retinolum [INN-Latin]

Retrovitamin A

Ro-a-vit

Rovimix A 500

SDCCGMLS-0066724.P001

Sehkraft A

SMP2_000102

SMR000112036

Solu-A

SPECTRUM1501203

Spectrum5_000993

Spectrum5_001997

ST057232

Super A

Testavol

Testavol S

Thalasphere

trans-retinol

trans-Retinol

trans-Retinol acid (Vitamin A)

trans-Vitamin A alcohol

tROL

UNII-81G40H8B0T

UNII-G2SH0XKK91

Vaflol

Vafol

Veroftal

Vi-.alpha.

Vi-a

Vi-Alpha

Vi-Dom-A

Vio-A

Vitamin a

Vitamin A

Vitamin- A

Vitamin A (Feed)

Vitamin A (USP)

Vitamin A alcohol

Vitamin- A alcohol

Vitamin A alcohol (VAN)

Vitamin- A alcohol solution

Vitamin A cryst

Vitamin a1

Vitamin A1

Vitamin- A1

Vitamin A1 alcohol

Vitamin A1 alcohol, all trans

Vitamin-?A

Vitamin-?A alcohol

Vitamin-?A alcohol solution

Vitamin-?A1

Vitamine A

Vitaminum A

Vitavel A

Vitavel-A

Vitpex

Vogan

Vogan-Neu

Vogan-nu

Wachstumsvitamin

WLN: L6UTJ A1 B1U1Y1&U2U1Y1&U2Q C1 C1

ZINC03831417

Zinosan N

Mafosfamide

Investigational

88859-04-5

Retinol palmitate

Adjuvants, Immunologic

Alkylating Agents

Antirheumatic Agents

Immunosuppressive Agents

retinol

Etoposide phosphate

Immunologic Factors

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Effects of Intrathoracic Pressure Regulation Therapy in Patients With Elevated Intracranial Pressure Due to Brain Injury or Intracranial Pathology	Terminated	NCT01824589	Phase 4
2	Pilot Study of Systemic and Intrathecal Chemotherapy Followed by Conformal Radiation for Infants With Brain Tumors	Completed	NCT00042367		Induction therapy (Regimen 1, Course 1, Cycle A1;Regimen 1, Course 1, Cycle A2 (Days 22 - 42);Cycle B;Regimen 1, Course 2;Intrathecal Mafosfamide;Regimen 1 Course 2, IT mafosfamide;Regimen 2, Course 1;Regimen 2, Course, 1, Cycle C1;Regimen 2, Course 2
3	Hypothalamic-pituitary Effects After Endoscopic Third Ventriculostomy	Terminated	NCT01675037

Search NIH Clinical Center for Obstructive Hydrocephalus

Sources

Genetic Tests for Obstructive Hydrocephalus

Sources

Anatomical Context for Obstructive Hydrocephalus

MalaCards organs/tissues related to Obstructive Hydrocephalus:

⁴⁰

Pineal, Brain, Pituitary, Spinal Cord, Cerebellum, Lung, Prostate

Sources

Publications for Obstructive Hydrocephalus

Articles related to Obstructive Hydrocephalus:

(show top 50) (show all 2069)

#	Title	Authors	PMID	Year
1	Visual loss in tuberous sclerosis. ⁶¹ ⁵⁴	Dotan SA...Gebarski SS	1745348	1991
2	Hydrocephalus Caused by Primary Fourth Ventricle Outlet Obstruction: Our Experience and Literature Review. ⁶¹	Krejci O...Lipina R	33444837	2021
3	Mis-diagnosed giant ovarian cyst and ventriculoperitoneal shunt malfunction. ⁶¹	Toubol A...Lejeune JP	33166567	2021
4	Transumbilical single-incision laparoscopically assisted ventriculoperitoneal shunting: a minimal invasive technique. ⁶¹	Zhu R...Yu H	33452618	2021
5	Hemicraniectomy and externalized ventricular drain placement in a pediatric patient with myelin oligodendrocyte glycoprotein-associated tumefactive demyelinating disease. ⁶¹	Sinha S...Lang SS	33796928	2021
6	[Hydrocephalus]. ⁶¹	Yamada S	33762452	2021
7	Delayed Obstructive Hydrocephalus After Cardiac Surgery With Cardiopulmonary Bypass in a Patient With Cerebellar Infarction: A Case Report. ⁶¹	Hoshino S...Takatori M	33783405	2021
8	Endoscopic Endonasal Transsphenoidal Approach for Third Ventriculostomy in the Management of Obstructive Hydrocephalus. ⁶¹	Liu B...He S	33710059	2021
9	Acute Presentation of Third Ventricular Cavernous Malformation following COVID-19 Infection in a Pregnant Woman: A Case Report. ⁶¹	Saberi H...Soltaninejad MJ	33771616	2021
10	Paediatric arachnoid cysts: Surgical outcomes from a Singapore children's hospital. ⁶¹	Chan JL...Low SYY	33581782	2021
11	Endoscopic Third Ventriculostomy in Infants Less than One Year of Age: A Short Series of 14 Cases. ⁶¹	Chowdhary S...Sharma SP	33652442	2021
12	Basilar artery occlusion presenting as sudden bilateral deafness: a case report. ⁶¹	Kinouchi T...Ueta H	33653404	2021
13	Acute Necrotizing Encephalopathy in a Four-Year-Old Boy. ⁶¹	Tsai CH...Lin WS	33809853	2021
14	Acoustic neuroma presenting as a hypnic headache. ⁶¹	Ceronie B...Cockerell OC	33687931	2021
15	Cerebellitis as a neurosurgical disease in pediatrics. ⁶¹	Goethe EA...Lam S	33581790	2021
16	The Third Eye Sees Double: Cohort Study of Clinical Presentation, Histology, Surgical Approaches, and Ophthalmic Outcomes in Pineal Region Germ Cell Tumors. ⁶¹	Takami H...Daniels DJ	33722723	2021
17	A case of rapid deterioration in a subacute period after endoscopic third ventriculostomy. ⁶¹	Ichinose T...Nakada M	33605824	2021
18	ETV for successful treatment of holocord syrinx with hydrocephalus: a case report. ⁶¹	Rose L...Sinha S	31994420	2021
19	Risk Analysis and Management of Third Ventricular Colloid Cysts. ⁶¹	Zeineddine HA...Day AL	33246179	2021
20	Post-operative seizure after first time endoscopic third ventriculostomy in pediatric patients. ⁶¹	Barkley AS...Hauptman JS	33599807	2021
21	Diagnosis and Therapeutic Management of Ventricular Gangliogliomas: An Illustrated Review. ⁶¹	Salge-Arrieta FJ...Ley-Urzaiz L	33548530	2021
22	Diffusion Tensor Imaging-Based Analysis of Baseline Neurocognitive Function and Posttreatment White Matter Changes in Pediatric Patients With Craniopharyngioma Treated With Surgery and Proton Therapy. ⁶¹	Uh J...Hua CH	32898610	2021
23	Management of Thromboembolic Complications During Aneurysm Coiling: 2-Dimensional Operative Video. ⁶¹	Domingo RA...We thank the ENRG Research Group	33571364	2021
24	Spinal Drop Metastasis of Glioblastoma-Two Case Reports, Clinicopathologic Features, Current Modalities of Evaluation, and Treatment with a Review of the Literature. ⁶¹	Pande A...Ghosh S	33161132	2021
25	Pineal Region Glioblastomas: Clinical Characteristics, Treatment, and Survival Outcome. ⁶¹	Niu X...Mao Q	33186787	2021
26	Neuropsychiatric systemic lupus erythematosus with cerebellar vasculitis and obstructive hydrocephalus requiring decompressive craniectomy. ⁶¹	Naito N...Nishioka Y	33021438	2021
27	Pre-operative headaches and obstructive hydrocephalus predict an extended length of stay following suboccipital decompression for pediatric Chiari I malformation. ⁶¹	Elsamadicy AA...DiLuna M	32519127	2021
28	Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development. ⁶¹	Xu H...Lehtinen MK	33469018	2021
29	Visual acuity loss and sixth nerve palsy as the only manifestations of slit ventricle syndrome. ⁶¹	Asensio-Sanchez VM...Garcia-Onrubia L	33478754	2021
30	Porencephalic cyst after endoscopic third ventriculostomy and Ommaya reservoir placement: case report and review of the literature. ⁶¹	Dominguez JF...Tobias ME	33442758	2021
31	Fatal Distant Venous Epidural Hematoma Following Posterior Cranial Fossa Surgery in a Twelve-Year old Child. ⁶¹	Ortiz-Ordonez A...Salman S	33598375	2021
32	Management of Obstructive Hydrocephalus Associated with Pineal Region Cysts and Tumors and Its Implication in Long-Term Outcome. ⁶¹	Choque-Velasquez J...Hernesniemi J	33516866	2021
33	Expanding the Horizons of mTOR Inhibitors for Treating Subependymal Giant Cell Astrocytomas with Obstructive Hydrocephalus. ⁶¹	Doddamani RS...Chandra PS	33508851	2021
34	[Diffuse subarachnoid haemorrhage with obstructive hydrocephalus in a 4-year-old girl]. ⁶¹	Gutierrez-Velez A...Darriba Alles JV	33526355	2021
35	Third Ventricle Cavernous Malformation and Obstructive Hydrocephalus Thought to Be a Colloid Cyst. ⁶¹	Chapman EK...Hadjipanayis CG	33010503	2021
36	Third ventricular colloid cyst causing acute hydrocephalus during early pregnancy: Clinical lessons from a case. ⁶¹	Foo CC...Kaliaperumal C	33654557	2021
37	Pediatric Fulminant Cerebellitis Is Still a Fatal Disease that We Know Little About! Two Case Reports and a Literature Review. ⁶¹	Alomani H...Aldhalan H	33454719	2021
38	Combined simultaneous endoscopic endonasal and microscopic transventricular surgery using a port retractor system for giant pituitary adenoma: A technical case report. ⁶¹	Yamada E...Ishikawa E	33767894	2021
39	Endoscopic Anatomy of Lateral and Third Ventricles: A must Know for Performing Endoscopic Third Ventriculostomy. ⁶¹	Sahana D...Sahu RK	33642269	2021
40	Case Report: Untreatable Headache in a Child With Ventriculoperitoneal Shunt Managed by Use of New Non-invasive Intracranial Pressure Waveform. ⁶¹	Paraguassu G...Frigieri G	33679296	2021
41	Endoscopic third ventriculostomy in children: problems and surgical outcome: analysis of 34 cases. ⁶¹	Rahman MM...Sarker MH	33407946	2021
42	Spontaneous regression of multiple intracranial capillary hemangiomas in a newborn-long-term follow-up and literature review. ⁶¹	Noureldine MHA...Arjipour M	33481102	2021
43	Artificial intelligence for automatic cerebral ventricle segmentation and volume calculation: a clinical tool for the evaluation of pediatric hydrocephalus. ⁶¹	Quon JL...Yeom KW	33260138	2020
44	Fetal and postnatal MRI findings of Blake pouch remnant causing obstructive hydrocephalus. ⁶¹	Nagaraj UD...Venkatesan C	33072233	2020
45	Acute Management of Gamma Knife Radiosurgery for Asymptomatic Obstructive Hydrocephalus Associated with Posterior Fossa Metastases. ⁶¹	Matsunaga S...Yamamoto T	32949796	2020
46	Unilateral mydriasis in a child with a ventriculoperitoneal shunt for obstructive hydrocephalus: a diagnostic dilemma. ⁶¹	Banerjee M...Gangadharan A	33370982	2020
47	Pattern of head circumference growth following bidirectional Glenn in infants with single ventricle heart disease. ⁶¹	Tseng SY...Heydarian HC	33303046	2020
48	Cranial Ultrasound Is an Important Tool in the Recognition of Life-Threatening Infratentorial Hemorrhage in Newborns. ⁶¹	van Steenis A...Steggerda SJ	33316833	2020
49	Entrapment of the temporal horn: case series and systematic review of literature. ⁶¹	Giugliano M...Santoro A	33297607	2020
50	The one-step edge-to-edge technique in ventriculoperitoneal shunt. ⁶¹	Umana GE...Alberio N	33284048	2020

Sources

Genes for Obstructive Hydrocephalus

Genes related to Obstructive Hydrocephalus (0 elite genes):

(show all 18)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubMed IDs
1	FOXJ1	Forkhead Box J1	Protein Coding	13.44	DISEASES inferred ¹⁵ GeneCards inferred via : Disorders (show sections)
2	AQP1	Aquaporin 1 (Colton Blood Group)	Protein Coding	12.84	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	PRL	Prolactin	Protein Coding	11.76	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
4	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	11.62	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
5	TSC1	TSC Complex Subunit 1	Protein Coding	8.65	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁴	1745348
6	RNU4ATAC	RNA, U4atac Small Nuclear (U12-Dependent Splicing)	RNA Gene	7.57	DISEASES inferred ¹⁵ ¹⁵
7	AQP4	Aquaporin 4	Protein Coding	6.76	DISEASES inferred ¹⁵
8	SYP	Synaptophysin	Protein Coding	6.68	DISEASES inferred ¹⁵
9	GFAP	Glial Fibrillary Acidic Protein	Protein Coding	6.24	DISEASES inferred ¹⁵
10	CCDC85C	Coiled-Coil Domain Containing 85C	Protein Coding	6.14	DISEASES inferred ¹⁵
11	NF1	Neurofibromin 1	Protein Coding	6.08	DISEASES inferred ¹⁵
12	AFP	Alpha Fetoprotein	Protein Coding	5.83	DISEASES inferred ¹⁵
13	OLIG2	Oligodendrocyte Transcription Factor 2	Protein Coding	5.75	DISEASES inferred ¹⁵
14	NF2	Neurofibromin 2	Protein Coding	5.71	DISEASES inferred ¹⁵
15	PLG	Plasminogen	Protein Coding	5.66	DISEASES inferred ¹⁵
16	ENO2	Enolase 2	Protein Coding	5.57	DISEASES inferred ¹⁵
17	DUSP16	Dual Specificity Phosphatase 16	Protein Coding	5.51	DISEASES inferred ¹⁵
18	MPDZ	Multiple PDZ Domain Crumbs Cell Polarity Complex Component	Protein Coding	5.5	DISEASES inferred ¹⁵

Sources

Variations for Obstructive Hydrocephalus

Sources

Expression for Obstructive Hydrocephalus

Search GEO for disease gene expression data for Obstructive Hydrocephalus.

Sources

Pathways for Obstructive Hydrocephalus

Pathways related to Obstructive Hydrocephalus according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Neuroscience ⁴	11.89	SYP NF2 NF1 GFAP ENO2
2	Spinal Cord Injury ¹	11.58	GFAP AQP4 AQP1
3	Neural Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁴	11.23	SYP OLIG2 GFAP
4	Glioblastoma Multiforme ⁶³	10.97	TSC1 NF2 NF1 MTOR
5	4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression ¹	10.51	TSC1 MTOR

Sources

GO Terms for Obstructive Hydrocephalus

Cellular components related to Obstructive Hydrocephalus according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	astrocyte end-foot	GO:0097450	8.62	GFAP AQP4

Biological processes related to Obstructive Hydrocephalus according to GeneCards Suite gene sharing:

(show all 12)

#	Name	GO ID	Score	Top Affiliating Genes
1	brain development	GO:0007420	9.73	NF2 NF1 MTOR FOXJ1
2	positive regulation of glial cell proliferation	GO:0060252	9.51	MTOR GFAP
3	response to nutrient levels	GO:0031667	9.5	TSC1 PRL MTOR
4	water transport	GO:0006833	9.49	AQP4 AQP1
5	negative regulation of macroautophagy	GO:0016242	9.48	TSC1 MTOR
6	regulation of cell-matrix adhesion	GO:0001952	9.46	TSC1 NF1
7	cerebral cortex development	GO:0021987	9.43	TSC1 NF1 CCDC85C
8	multicellular organismal water homeostasis	GO:0050891	9.4	AQP4 AQP1
9	negative regulation of cell size	GO:0045792	9.37	TSC1 MTOR
10	cellular water homeostasis	GO:0009992	9.16	AQP4 AQP1
11	positive regulation of stress fiber assembly	GO:0051496	9.13	TSC1 NF2 MTOR
12	negative regulation of MAPK cascade	GO:0043409	8.8	NF2 NF1 DUSP16

Molecular functions related to Obstructive Hydrocephalus according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	water channel activity	GO:0015250	8.62	AQP4 AQP1

Sources

Sources for Obstructive Hydrocephalus

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 20-May-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ Tocris

⁷⁰ UMLS

⁷¹ UMLS via Orphanet

⁷² UniProtKB/Swiss-Prot

⁷³ Wikipedia