Obstructive Hydrocephalus disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: OBS004 MIFTS: 46	Obstructive Hydrocephalus Categories: Neuronal diseases
Genes Tissues Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Obstructive Hydrocephalus

MalaCards integrated aliases for Obstructive Hydrocephalus:

Name: Obstructive Hydrocephalus ¹² ⁵⁴ ¹⁵ ⁷¹ ³²

Classifications:

MalaCards categories:
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

ICD10: ³²

Diseases of the nervous system

Other disorders of the nervous system

Hydrocephalus

Obstructive hydrocephalus

External Ids:

Disease Ontology ¹² DOID:14159

ICD9CM ³⁴ 331.4

MeSH ⁴³ D006849

NCIt ⁴⁹ C116347

SNOMED-CT ⁶⁷ 230746009

ICD10 ³² G91.1

UMLS ⁷¹ C0549423

Sources

Summaries for Obstructive Hydrocephalus

MalaCards based summary : Obstructive Hydrocephalus is related to cellular ependymoma and subependymal giant cell astrocytoma. An important gene associated with Obstructive Hydrocephalus is FOXJ1 (Forkhead Box J1), and among its related pathways/superpathways are Regulation of lipid metabolism Insulin signaling-generic cascades and Neuroscience. The drugs Pharmaceutical Solutions and Vincristine have been mentioned in the context of this disorder. Affiliated tissues include brain, pineal and pituitary, and related phenotypes are behavior/neurological and growth/size/body region

Sources

Related Diseases for Obstructive Hydrocephalus

Diseases related to Obstructive Hydrocephalus via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 435)

#	Related Disease	Score	Top Affiliating Genes
1	cellular ependymoma	32.8	SYP OLIG2 FOXJ1
2	subependymal giant cell astrocytoma	31.4	TSC2 TSC1 SYP GFAP ENO2
3	intracranial hypertension	31.3	PRL AQP4 AQP1
4	communicating hydrocephalus	31.0	ZIC3 AQP4 AQP1
5	chiari malformation	30.9	SYP GFAP AQP1
6	head injury	30.5	PRL ENO2
7	neurilemmoma of the fifth cranial nerve	30.4	NF2 CRLF1
8	pineoblastoma	30.3	SYP GFAP AFP
9	pineocytoma	30.1	SYP GFAP ENO2
10	intracranial cysts	30.1	GFAP ENO2
11	brain stem infarction	30.0	PLG PLAT CRLF1
12	arachnoiditis	30.0	RICTOR CRLF1 AQP4
13	hydrocephalus	30.0	ZIC3 SYP PRL PLAT GFAP FOXJ1
14	traumatic brain injury	29.9	GFAP ENO2 AQP4
15	brain edema	29.8	PLAT GFAP AQP4 AQP1
16	syringomyelia	29.7	RICTOR GFAP CRLF1 AQP4
17	juvenile pilocytic astrocytoma	29.7	SYP OLIG2 NF1 GFAP
18	hemangioblastoma	29.6	SYP GFAP ENO2 AQP1
19	spinal meningioma	29.6	NF2 NF1
20	neurilemmoma	29.6	NF2 NF1 GFAP ENO2
21	pineal gland cancer	29.5	SYP GFAP ENO2 AFP
22	acoustic neuroma	29.5	NF2 NF1 CRLF1 AQP4 AQP1
23	central neurocytoma	29.4	SYP OLIG2 GFAP ENO2
24	tuberous sclerosis 1	29.3	TSC2 TSC1 RICTOR
25	gastrointestinal stromal tumor	29.1	SYP NF2 NF1 ENO2
26	cerebral degeneration	29.0	ZIC3 SYP OLIG2 GFAP FOXJ1 AQP4
27	glioblastoma multiforme	28.4	TSC2 TSC1 SYP NF2 NF1 GFAP
28	meningioma, familial	28.2	SYP RICTOR PRL NF2 NF1 GFAP
29	benign ependymoma	28.2	TSC2 TSC1 SYP NF2 NF1 GFAP
30	medulloblastoma	27.9	TSC2 SYP RICTOR NF1 GFAP ENO2
31	tuberous sclerosis	27.6	TSC2 TSC1 SYP RICTOR NF2 NF1
32	hydrocephalus, congenital, 1	11.7
33	hydrocephalus due to congenital stenosis of aqueduct of sylvius	11.6
34	congenital hydrocephalus	11.5
35	ciliary dyskinesia, primary, 43	11.4
36	congenital communicating hydrocephalus	11.4
37	megalencephaly-capillary malformation-polymicrogyria syndrome	11.2
38	extraventricular neurocytoma	10.5	SYP GFAP
39	desmoplastic infantile ganglioglioma	10.5	SYP GFAP
40	dysferlinopathy	10.5	AQP4 AQP1
41	lung combined type small cell carcinoma	10.5	SYP GFAP
42	angiocentric glioma	10.5	SYP GFAP
43	non-gestational ovarian choriocarcinoma	10.5	PRL AFP
44	thymus sarcomatoid carcinoma	10.4	SYP AFP
45	rectum neuroendocrine neoplasm	10.4	SYP AFP
46	abducens nerve disease	10.4	PRL AQP4
47	medullomyoblastoma	10.4	SYP GFAP
48	hematocele of tunica vaginalis testis	10.4	CRLF1 AFP
49	papillary thymic adenocarcinoma	10.4	SYP AFP
50	urachal adenocarcinoma	10.4	NF1 AFP

Comorbidity relations with Obstructive Hydrocephalus via Phenotypic Disease Network (PDN): (show all 18)

Acute Cystitis	Alzheimer Disease
Brain Cancer	Brain Compression
Cerebellum Cancer	Cerebral Degeneration
Communicating Hydrocephalus	Decubitus Ulcer
Deficiency Anemia	Epilepsy, Focal, with Speech Disorder and with or Without Mental Retardation
Hypertension, Essential	Parkinson Disease, Late-Onset
Pineal Gland Cancer	Protein-Energy Malnutrition
Respiratory Failure	Schizophreniform Disorder
Swallowing Disorders	Transient Cerebral Ischemia

Graphical network of the top 20 diseases related to Obstructive Hydrocephalus:

Sources

Symptoms & Phenotypes for Obstructive Hydrocephalus

MGI Mouse Phenotypes related to Obstructive Hydrocephalus:

⁴⁵ (show all 14)

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	behavior/neurological	MP:0005386	10.44	AFP AQP1 AQP4 CRLF1 ENO2 FOXJ1
2	growth/size/body region	MP:0005378	10.32	AQP1 AQP4 ENO2 FOXJ1 GFAP NF1
3	mortality/aging	MP:0010768	10.31	AFP AQP1 AQP4 CCDC85C CRLF1 FOXJ1
4	cardiovascular system	MP:0005385	10.3	AQP1 AQP4 CCDC85C FOXJ1 GFAP NF1
5	cellular	MP:0005384	10.25	ENO2 FOXJ1 GFAP NF1 OLIG2 PLAT
6	nervous system	MP:0003631	10.25	AQP1 AQP4 CCDC85C CRLF1 ENO2 FOXJ1
7	endocrine/exocrine gland	MP:0005379	10.24	AFP AQP1 AQP4 NF1 NF2 PLAT
8	liver/biliary system	MP:0005370	10.09	AFP NF1 NF2 PLG PRL RICTOR
9	neoplasm	MP:0002006	10.02	AFP NF1 NF2 OLIG2 PLG PRL
10	hearing/vestibular/ear	MP:0005377	9.93	AQP1 AQP4 NF1 NF2 PLAT ZIC3
11	reproductive system	MP:0005389	9.93	AFP AQP1 FOXJ1 NF1 NF2 PLAT
12	renal/urinary system	MP:0005367	9.86	AQP1 AQP4 NF1 NF2 PLG RICTOR
13	respiratory system	MP:0005388	9.7	AQP1 AQP4 ENO2 FOXJ1 NF1 NF2
14	vision/eye	MP:0005391	9.32	AQP1 AQP4 GFAP NF1 NF2 OLIG2

Sources

Drugs & Therapeutics for Obstructive Hydrocephalus

Drugs for Obstructive Hydrocephalus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 20)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Pharmaceutical Solutions

Phase 1, Phase 2

Vincristine

Approved, Investigational

57-22-7, 2068-78-2

5978

Synonyms:

22-Oxovincaleukoblastin

22-Oxovincaleukoblastine

28379-27-3

57-22-7

AC1L1LJC

C07204

C46H56N4O10

CCRIS 5763

Cellcristin

CHEBI:28445

CID5978

Citomid

D08679

DB00541

EINECS 200-318-1

Farmistin

HMS2090E19

HSDB 3199

Indole alkaloid

LCR

Leurocristine

Lilly 37231 (1:1 sulfate salt)

Liposomal Vincristine

LS-228

Marqibo

NCGC00163700-01

NCI60_026703

NCI-C04864

NSC-67574

Onco TCS

Oncovin

Oncovin (1:1 sulfate salt)

Oncovine

Onkocristin

PFS, Vincasar

Sulfate, vincristine

Tecnocris

Tecnocris (TN)

UNII-5J49Q6B70F

VCR

VIN

Vincaleukoblastine, 22-oxo- 22-Oxovincaleukoblastine

Vincasar

Vincasar (1:1 sulfate salt)

Vincasar PFS

Vincrex

Vincrex (1:1 sulfate salt)

Vincristin

Vincristin bristol

Vincristin medac

Vincristina

Vincristina [DCIT]

vincristine

Vincristine

Vincristine (INN)

Vincristine [INN:BAN]

Vincristine sulfate

Vincristine Sulfate

Vincristine Sulfate PFS

Vincristinum

Vincristinum [INN-Latin]

Vincrisul

Vincrstine

Vincrystine

Vinkristin

Vintec

Z-D-Val-lys(Z)-OH

Z-D-Val-Lys(Z)-OH

Mesna

Approved, Investigational

3375-50-6

598

Synonyms:

1-THIOETHANEsulfonate

1-THIOETHANEsulfonIC ACID

1-THIOETHANEsulphonate

1-THIOETHANEsulphonic acid

2 Mercaptoethanesulfonate

2-Mercaptoethane

2-Mercaptoethanesulfonate

2-mercaptoethanesulfonic acid

2-Mercaptoethanesulfonic acid

2-Mercaptoethanesulphonate

2-Mercaptoethanesulphonate, sodium

2-mercaptoethanesulphonic acid

2-Mercaptoethanesulphonic acid

2-mercaptoethylsulfonate

2-Mercaptoethylsulfonate

2-Mercaptoethylsulfonic acid

2-Mercaptoethylsulphonate

2-Mercaptoethylsulphonic acid

2-sulfanylethylsulfonate

2-Sulfanylethylsulfonate

2-Sulfanylethylsulfonic acid

2-Sulphanylethylsulphonate

2-Sulphanylethylsulphonic acid

ASTA D 7093

ASTA medica brand OF mesna

ASTAD 7093

ASTA-D 7093

beta-Mercaptoethanesulfonate

beta-Mercaptoethanesulfonic acid

beta-Mercaptoethanesulphonate

beta-Mercaptoethanesulphonic acid

b-Mercaptoethanesulfonate

b-Mercaptoethanesulfonic acid

b-Mercaptoethanesulphonate

b-Mercaptoethanesulphonic acid

Bristol myers squibb brand OF mesna

Bristol-myers squibb brand OF mesna

Cell pharm brand OF mesna

Coenzima m

Coenzima M

Coenzym m

Coenzym M

Coenzyme m

CoM

HS-CoM

Kendrick brand OF mesna

MESNA cell

Mesna kendrick brand

Mesna sanfer brand

MESNA-cell

Mesnex

Mesnum

Mistabron

Mistabronco

Mitexan

Mucofluid

reduced coenzyme M

Reduced coenzyme m

reduced CoM

Reduced com

Sanfer brand OF mesna

Sodium 2-mercaptoethanesulphonate

UCB brand OF mesna

Uromitexan

Ziken

β-mercaptoethanesulfonate

β-mercaptoethanesulfonic acid

β-mercaptoethanesulphonate

β-mercaptoethanesulphonic acid

Etoposide

Approved

33419-42-0

36462

Synonyms:

(−)-etoposide

(-)-Etoposide

121471-01-0

136598-18-0

201594-04-9

33419-42-0

35317-32-9

4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-b-D-glucopyranoside)

4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)

4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-β-D-glucopyranoside)

4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside)

4'-Demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside

4-Demethylepipodophyllotoxin b-D-ethylideneglucoside

4-Demethylepipodophyllotoxin beta-D-ethylideneglucoside

4'-Demethylepipodophyllotoxin ethylidene-.beta.-D-glucoside

4-demethylepipodophyllotoxin β-D-ethylideneglucoside

4-Demethylepipodophyllotoxin β-D-ethylideneglucoside

4-Demethylepipodophyllotoxin-.beta.-D-ethylideneglucoside

4'-O-Demethyl-1-O-(4,6-O-ethylidene-beta-D-glucopyranosyl)epipodophyllotoxin

51854-34-3

76576-58-4

9-((4,6-O-Ethylidine-b-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-D)-1,3-dioxol-6(5ah)-one

9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-one

9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-D)-1,3-dioxol-6(5ah)-one

9-((4,6-O-Ethylidine-β-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-D)-1,3-dioxol-6(5ah)-one

AB00438905

AC1L1FN8

AC1L1VT3

AC1L6246

AC1NR4OG

AC1O4WGG

AC1O7M1N

AC1Q47JJ

alpha-D-Glucopyranosyl isomer etoposide

Ambap33419-42-0

Baxter brand OF etoposide

Baxter oncology brand OF etoposide

Bio1_000489

Bio1_000978

Bio1_001467

BPBio1_000673

BRD-K37798499-001-02-5

Bristol myers brand OF etoposide

Bristol myers squibb brand OF etoposide

Bristol-myers brand OF etoposide

Bristol-myers squibb brand OF etoposide

BSPBio_000611

C01576

CCRIS 2392

Celltop

CHEBI:4911

CHEBI:588795

CHEMBL44657

CID11758093

CID284997

CID3310

CID36462

CID5284558

CID6419930

CID6610299

CPD000112002

D00125

DB00773

DEMETHY-EPIPODOPHYLLOTOXIN,ETHYLIDENE GLUCOSIDE,

Demethyl epipodophyllotoxin ethylidine glucoside

Demethyl Epipodophyllotoxin Ethylidine Glucoside

Demethyl-epiodophyllotoxin ethylidene glucoside

Demethylepipodophyllotoxin-beta-D-ethylideneglucoside

E0675

E1383_SIGMA

EINECS 251-509-1

Epipodophyllotoxin VP-16213

Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-.beta.-D-glucopyranoside

Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside

Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside (8CI)

Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-.beta.-D-glucopyranoside)

Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-beta-D-glucopyranoside)

Eposide

Eposin

Eposin, Vepesid, VP-16, Toposar, Etoposide

eto GRY

eto-GRY

Etomedac

ETOP

Etopol

Etopophos

Etopophos (phosphate salt)

Etopos

etoposide

Etoposide

Etoposide (JP15/USP/INN)

Etoposide (VP16)

Etoposide [USAN:INN:BAN:JAN]

Etoposide pierre fabre

Etoposide teva

Etoposide, (5a alpha)-isomer

Etoposide, (5a alpha,9 alpha)-isomer

Etoposide, (5S)-isomer

Etoposide, alpha D glucopyranosyl isomer

Etoposide, alpha-D-glucopyranosyl isomer

Etoposido

Etoposido [INN-Spanish]

etoposido Ferrer farma

Etoposidum

Etoposidum [INN-Latin]

Etosid

Exitop

Ferrer brand OF etoposide

Gry brand OF etoposide

HMS1569O13

HMS2052N05

HMS2089F14

HSDB 6517

I06-0248

KBioSS_002410

Lastet

Lemery brand OF etoposide

LS-1214

Medac brand OF etoposide

MLS000049957

MLS001074951

MLS001424283

MLS002153463

MLS002207239

MLS002222184

MolPort-003-983-431

MolPort-004-905-001

MolPort-004-955-161

NCGC00025056-02

NChemBio.2007.10-comp19

nchembio.573-comp8

nchembio873-comp2

NK 171

Novartis brand OF etoposide

NSC 141540

NSC141540

NSC-141540

Onkoposid

Onkoworks brand OF etoposide

Pharmachemie brand OF etoposide

Pierre fabre brand OF etoposide

Prasfarma brand OF etoposide

Prestwick_211

Prestwick0_000396

Prestwick1_000396

Prestwick2_000396

Prestwick3_000396

Riboposid

Ribosepharm brand OF etoposide

S1225_Selleck

SAM001246880

Sanfer brand OF etoposide

SMR000112002

SPBio_002532

ST056353

Tedec meiji brand OF etoposide

Teva brand OF etoposide

Toposar

trans-Etoposide

UNII-6PLQ3CP4P3

Vepesid

VePesid

VePESID (TN)

Vepesid J

Vepeside

Vépéside sandoz

Vépéside-sandoz

VP 16

VP 16 (pharmaceutical)

VP 16213

VP 16-213

VP-16

VP-16-213

ZINC03830818

ZINC03938684

Zuyeyidal

Cisplatin

Approved

15663-27-1

2767 441203 84093

Synonyms:

(SP-4-1)-diamminedichloridoplatinum

(SP-4-1)-diamminedichloroplatinum

(SP-4-2)-diamminedichloridoplatinum

(SP-4-2)-diamminedichloroplatinum

Abiplatin

Biocisplatinum

Briplatin

CACP

Carboquone

CDDP

CHEBI:35852

CID441203

Cis Pt II

cis-[PtCl2(NH3)2]

cis-DDP

Cis-DDP

Cis-Diaminedichloroplatinum

cis-diamminedichloridoplatinum(II)

cis-Diamminedichloroplatinum

Cis-Diamminedichloroplatinum

cis-diamminedichloroplatinum(II)

cis-Dichlorodiammineplatinum(II)

Cismaplat

Cisplatin

Cisplatine

cisplatino

Cisplatino

Cisplatinum

Cisplatyl

Citoplationo

CPD0-1392

CPDC

CPDD

DB00515

DDP

DDPT

Diamminedichloroplatinum

EU-0100918

Lederplatin

nchembio773-comp1

Neoplatin

Peyrone's chloride

Peyrone's salt

Plastin

Platamine

Platiblastin

Platidiam

Platinex

Platinol

Platinol-AQ

Platinoxan

Platinum Ammine Chloride

Platinum Ammonium Chloride

Platinum Diamine Dichloride

Randa

trans-DDP

Trans-DDP

Trans-Diaminedichloroplatinum

trans-diamminedichloridoplatinum(II)

Trans-Diamminedichloroplatinum

Trans-Dichlorodiammine Platinum

Trans-Platinumdiammine Dichloride

Mannitol

Approved, Investigational

69-65-8

6251 453

Synonyms:

(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexaol

(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol

(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol

(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexol

(L)-Mannitol

1,2,3,4,5,6-Hexanehexol

123897-58-5

133-43-7

15719_ALDRICH

15719_RIEDEL

33440_RIEDEL

33440_SIGMA

36413-61-3

4-01-00-02841 (Beilstein Handbook Reference)

5149-40-6

63559_FLUKA

63559_SIGMA

63560_FLUKA

63565_FLUKA

63565_SIGMA

69-65-8

75398-80-0

85085-15-0

87-78-5

AB1002081

AC-12776

AC1L1M49

AC1Q28E5

AI3-19511

Ambap69-65-8

AR-1J3861

bmse000099

BRN 1721898

C00392

C6H14O6

CCRIS 369

CHEBI:16899

CHEMBL689

CID6251

Cordycepate

Cordycepic acid

cpd without stereochemical designation

D-(-)-Mannitol

D00062

D008353

Diosmol

DL-Mannitol

D-mannite

D-mannitol

D-Mannitol

D-Mannitol (JP15)

Dulcite

e 421

e421

e-421

ED1D1E61-FEFB-430A-AFDC-D1F4A957FC3D

EINECS 200-711-8

EINECS 201-770-2

Hexahydroxyhexane

Hexanhexol

HSDB 714

Invenex

Isotol

LS-1588

LS-89250

M0044

M1902_SIGMA

M4125_SIAL

M8429_SIAL

M9546_SIAL

M9647_SIAL

Manicol

manita

Manitol

Maniton S

Maniton-S

Manna sugar

Manna Sugar

Mannazucker

Mannidex

Mannidex 16700

Mannigen

Mannistol

Mannit

Mannit P

Mannite

mannitol

Mannitol

Mannitol (USP)

Mannitol (VAN)

Mannitol [USAN]

Mannitol 10%

Mannitol 10% In Plastic Container

MANNITOL 10% W/ DEXTROSE 5% IN DISTILLED WATER

Mannitol 15%

Mannitol 15% In Plastic Container

MANNITOL 15% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.45%

Mannitol 20%

Mannitol 20% In Plastic Container

MANNITOL 25%

Mannitol 5%

Mannitol 5% In Plastic Container

MANNITOL 5% W/ DEXTROSE 5% IN SODIUM CHLORIDE 0.12%

Mannitolum

Mannogem 2080

Marine crystal

Marine Crystal

MLS001335977

MLS001335978

MolPort-003-927-039

MTL

Mushroom sugar

NCGC00164246-01

NCI-C50362

NSC 407017

NSC 9256

Osmitrol

Osmitrol (TN)

Osmitrol 10% In Water

OSMITROL 10% IN WATER IN PLASTIC CONTAINER

Osmitrol 15% In Water

OSMITROL 15% IN WATER IN PLASTIC CONTAINER

Osmitrol 20% In Water

OSMITROL 20% IN WATER IN PLASTIC CONTAINER

Osmitrol 5% In Water

OSMITROL 5% IN WATER IN PLASTIC CONTAINER

Osmofundin

Osmosal

Resectisol

Resectisol In Plastic Container

SDM no. 35

SDM No. 35

SMR000857324

Sorbitol-Mannitol

SORBITOL-MANNITOL IN PLASTIC CONTAINER

TL806434

UNII-3OWL53L36A

ZINC02041302

Cyclophosphamide

Approved, Investigational

50-18-0, 6055-19-2

2907

Synonyms:

(-)-Cyclophosphamide

(+-)-Cyclophosphamide

(RS)-Cyclophosphamide

1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine

1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin

2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide

4-Hydroxy-cyclophosphan-mamophosphatide

50-18-0

60007-95-6

6055-19-2 (monohydrate)

75526-90-8

AC1L1EQQ

AI3-26198

Anhydrous cyclophosphamide

Anhydrous, cyclophosphamide

ASTA

Asta B 518

ASTA B518

B 518

B-518

bis(2-Chloroethyl)phosphami de cyclic propanolamide

bis(2-Chloroethyl)phosphamide cyclic propanolamide ester

Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester

BRN 0011744

BSPBio_002099

C 0768

C07888

C7H15Cl2N2O2P

CB 4564

CB-4564

CCRIS 188

CHEBI:4027

CHEMBL32520

CHEMBL88

Ciclofosfamida

Ciclofosfamida [INN-Spanish]

Ciclofosfamide

Ciclophosphamide

Ciclophosphamide [INN]

CID2907

Clafen

Claphene

CPA

CTX

Cycloblastin

Cyclophosphamid

cyclophosphamide

Cyclophosphamide

Cyclophosphamide (anhydrous form)

Cyclophosphamide (anhydrous)

Cyclophosphamide (INN)

Cyclophosphamide (TN)

Cyclophosphamide anhydrous

Cyclophosphamide monohydrate

Cyclophosphamide Monohydrate

Cyclophosphamide Sterile

Cyclophosphamide, (+-)-Isomer

Cyclophosphamide, (R)-isomer

Cyclophosphamide, (S)-isomer

Cyclophosphamides

Cyclophosphamidum

Cyclophosphamidum [INN-Latin]

Cyclophosphan

Cyclophosphane

Cyclophosphanum

Cyclophosphoramide

Cyclostin

Cyklofosfamid

Cyklofosfamid [Czech]

Cytophosphan

Cytophosphane

Cytoxan

Cytoxan (TN)

Cytoxan Lyoph

D,L-Cyclophosphamide

D07760

DB00531

DivK1c_000246

EINECS 200-015-4

Endoxan

Endoxan R

Endoxana

Endoxanal

Endoxan-Asta

Endoxane

Enduxan

EU-0100238

Genoxal

Hexadrin

HMS2090A12

HSDB 3047

IDI1_000246

KBio1_000246

KBio2_001338

KBio2_003906

KBio2_006474

KBio3_001319

KBioGR_000888

KBioSS_001338

Lopac0_000238

Lopac-C-0768

LS-1302

LS-99787

Lyophilized Cytoxan

Mitoxan

MolPort-001-783-420

Monohydrate, cyclophosphamide

N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide

N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide

NCGC00015209-01

NCGC00015209-03

NCGC00015209-06

NCGC00091741-02

NCGC00091741-03

NCI60_002097

NCI-C04900

Neosar

NINDS_000246

NSC 26271

NSC26271

NSC-26271

NSC273033

NSC273034

Occupation, cyclophosphamide exposure

Procytox

RCRA waste no. U058

Rcra waste number U058

Rcra Waste Number U058

Revimmune

S1217_Selleck

Semdoxan

Sendoxan

Senduxan

SK 20501

SPBio_001071

Spectrum_000858

Spectrum2_001146

Spectrum3_000370

Spectrum4_000304

Spectrum5_000795

STK177249

STOCK2S-91217

UNII-6UXW23996M

WLN: T6MPOTJ BO BN2G2G

Zyklophosphamid

Zyklophosphamid [German]

Magnesium Sulfate

Approved, Investigational, Vet_approved

7487-88-9

24083

Synonyms:

(C10-C16) Alkylalcohol sulfuric acid, magnesium salt

00627_FLUKA

10028-26-9

10034-99-8 (heptahydrate)

13143_RIEDEL

13143_SIAL

139939-75-6

18939-43-0

203726_ALDRICH

208094_SIAL

34276_FLUKA

34276_RIEDEL

38146_FLUKA

38146_RIEDEL

63126_FLUKA

63136_FLUKA

63136_SIAL

63139_FLUKA

63139_SIAL

68081-97-0

7487-88-9

AC1L2N76

AC1LAX36

AC1Q1U66

AI3-02029

Bitter salt

C10-C16 Alkyl alcohol sulfuric acid magnesium salt

Caswell No. 534

CCRIS 8411

CHEBI:32599

CID24083

CPD0-2390

D008278

DB00653

EINECS 231-298-2

EINECS 233-073-4

EINECS 242-691-3

EINECS 268-365-0

EPA Pesticide Chemical Code 050503

Epsom salt

Hair salt

Heptahydrate Magnesium Sulfate

HSDB 664

Kieserite [as monohydrate]

LS-88605

M2643_SIGMA

M3409_SIGMA

M7506_SIAL

M8150_SIGMA

Magnesium bisulfate

Magnesium hydrogensulphate

MAGNESIUM SULFATE

Magnesium sulfate (1:1)

Magnesium sulfate anhydrous

Magnesium sulfate dried

Magnesium sulfate hexahydrate

Magnesium sulfate in dextrose 5% in plastic container

Magnesium Sulfate In Plastic Container

Magnesium sulfate solution

Magnesium Sulfate, Heptahydrate

Magnesium sulphate

Magnesium Sulphate Hydrate

magnesium(2+) ion sulfate

magnesium(II) sulfate

Magnesium(II) sulfate

Magnesiumsulfat

MgSO4

MolPort-003-925-000

NSC 146179

OT-S

OT-S (drying agent)

Sal amarum

Sal Angalis

Sal anglicum

Sal catharticum

Sal De sedlitz

Sal seidlitense

Salts of england

SDA 15-062-07

Sel d'angleterre

Sulfate, Magnesium

Sulfuric acid magnesium salt

Sulfuric acid magnesium salt (1:1)

Sulfuric acid magnesium salt (VAN)

Sulfuric acid, C10-16 alkyl ester, magnesium salt

Sulfuric acid, magnesium salt

Sulfuric acid, magnesium salt (1:1)

Sulfuric acid, mono-C10-16-alkyl esters, magnesium salts

Tomix OT

UNII-DE08037SAB

UNII-ML30MJ2U7I

Vitamin A

Approved, Nutraceutical, Vet_approved

22737-96-8, 68-26-8, 11103-57-4

9904001 445354

Synonyms:

(11-cis,13-cis)-Retinol acetate

(13cis)-Retinol

(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol

(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol

(2Z,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol

(all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol

.alpha.lin

.alpha.sterol

.beta.-Retinol

[11,12-3H]-Retinol

11,13-Di-cis-vitamin a acetate

11103-57-4

11-cis-13-cis-Retinol acetate

11-cis-13-cis-Retinyl acetate

13123-33-6

1341-18-0

1406-67-3

17104-91-5

1rbp

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclchexen-1-yl)-2,4,6,8-nonatetraen-1-ol

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonate-traen-1-ol

3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol, (all-E)-Isomer

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-2,4,6,8-nonatetraen-1-ol

4-06-00-04133 (Beilstein Handbook Reference)

53637-36-8

5979-23-7

68-26-8

95144_FLUKA

95144_SIGMA

95146_FLUKA

95146_SIGMA

AC-11701

AC1L9HU3

AC1Q7BU9

ACON

Afaxin

Agiolan

Agoncal

Alcohol 9,13-dimethyl-7-(1,1,5-trimethyl-6-cyclohexen-5-yl)-7,9,11,13-nonatetraen-15-ol

Alcovit A

alin

All Trans Retinol

All-trans retinol

ALL-TRANS RETINOL (SEE ALSO RETINOID PROJECT 1)

all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol

all-trans-retinol

all-trans-Retinol

all-trans-retinyl alcohol

all-trans-Retinyl alcohol

all-trans-Vitamin A

all-trans-vitamin A alcohol

all-trans-Vitamin A alcohol

all-trans-Vitamin A1

Alphalin

Alphasterol

A-Mulsal

Anatola

Anatola A

Anti-infective vitamin

Antixerophthalmic vitamin

Antixerophthalmisches Vitamin

Aoral

Apexol

Apostavit

Aquasol A Parenteral

Aquasynth

AR-1L3057

A-Sol

Atars

ATAV

Avibon

A-Vi-Pel

Avita

A-Vitan

Avitol

Axerol

Axerophthol

Axerophtholum

Bentavit A

beta-Retinol

BIDD:PXR0102

Biosterol

BRN 0403040

C00473

C17276

C20H30O

CCRIS 5444

CHEBI:17336

CHEMBL986

Chocola A

CID445354

Cylasphere

D014801

D06543

DB00162

Del-VI-A

Disatabs Tabs

Dofsol

Dohyfral A

EINECS 200-683-7

EINECS 234-328-2

Epiteliol

Hi-A-Vita

HMS1921B04

HMS2092L13

HMS501I08

Homagenets Aoral

Homagenets aorl

HSDB 815

Hydrovit A

IDI1_000486

Lard Factor

LMPR01090001

LPK

LS-1578

M.V.C. 9+3

M.V.I.-12

MLS001066379

MLS001074751

MolPort-001-785-962

Mvc Plus

Myvpack

NCGC00091784-01

NCGC00091784-02

NCGC00091784-03

NCGC00091784-04

NCGC00091784-05

NCGC00091784-06

Nio-A-Let

NSC 122759

NSC122759

Oleovitamin A

Ophthalamin

Plivit A

Prepalin

R7632_SIGMA

Retin-11,12-t2-ol (9CI)

retinol

Retinol

RETINOL

Retinol [INN:BAN]

Retinol solution

Retinol-(cellular-retinol-binding-protein)

Retinol, all-trans- (8CI)

Retinolo

Retinolo [DCIT]

Retinolum

Retinolum [INN-Latin]

Retrovitamin A

Ro-a-vit

Rovimix A 500

SDCCGMLS-0066724.P001

Sehkraft A

SMP2_000102

SMR000112036

Solu-A

SPECTRUM1501203

Spectrum5_000993

Spectrum5_001997

ST057232

Super A

Testavol

Testavol S

Thalasphere

trans-retinol

trans-Retinol acid (Vitamin A)

trans-Vitamin A alcohol

tROL

UNII-81G40H8B0T

UNII-G2SH0XKK91

Vaflol

Vafol

Veroftal

Vi-.alpha.

Vi-a

Vi-Alpha

Vi-Dom-A

Vio-A

Vitamin A

Vitamin- A

Vitamin A (Feed)

Vitamin A (USP)

Vitamin A alcohol

Vitamin- A alcohol

Vitamin A alcohol (VAN)

Vitamin- A alcohol solution

Vitamin A cryst

Vitamin A1

Vitamin- A1

Vitamin A1 alcohol

Vitamin A1 alcohol, all trans

Vitamin-?A

Vitamin-?A alcohol

Vitamin-?A alcohol solution

Vitamin-?A1

Vitamine A

Vitaminum A

Vitavel A

Vitavel-A

Vitpex

Vogan

Vogan-Neu

Vogan-nu

Wachstumsvitamin

WLN: L6UTJ A1 B1U1Y1&U2U1Y1&U2Q C1 C1

ZINC03831417

Zinosan N

Mafosfamide

Investigational

88859-04-5

Anesthetics

Tissue Plasminogen Activator

Immunologic Factors

retinol

Retinol palmitate

Adjuvants, Immunologic

Etoposide phosphate

Alkylating Agents

Immunosuppressive Agents

Antirheumatic Agents

Interventional clinical trials:

(show all 14)

#	Name	Status	NCT ID	Phase	Drugs
1	Effects of Intrathoracic Pressure Regulation Therapy in Patients With Elevated Intracranial Pressure Due to Brain Injury or Intracranial Pathology	Terminated	NCT01824589	Phase 4
2	Lumbar Drainage for Communicating Hydrocephalus After Intraventricular Hemorrhage: a Randomised, Controlled Trial(LUCAS-IVH: LUmbar CAtheter for Severe IntraVentricular Hemorrhage)	Completed	NCT01041950	Phase 2, Phase 3
3	Voices of Patients' Relatives to Support Weaning From Mechanical Ventilation in Patients With Severe Brain Injury - VOICE-WEANING, a Randomized Clinical Trial	Recruiting	NCT03795623	Phase 2, Phase 3
4	A Placebo-Controlled, Observer-Blinded, Crossover Study to Evaluate the Safety and Effectiveness of a Single, Autologous, Cord Blood Stem Cell Infusion for the Treatment of Cerebral Palsy in Children	Terminated	NCT01072370	Phase 1, Phase 2
5	A Prospective Randomized, Controlled Trial for Treatment of Intraventricular Hemorrhage: External Ventricular Drainage and Intraventricular Thrombolysis vs. External Ventricular Drainage and Endoscopic Evacuation	Unknown status	NCT01064011
6	A Randomized Controlled Trial of Endoscopic Third Ventriculostomy Versus Ventricular Shunt for Children With Communicating Hydrocephalus	Completed	NCT01801267
7	Pilot Study of Systemic and Intrathecal Chemotherapy Followed by Conformal Radiation for Infants With Brain Tumors	Completed	NCT00042367		Induction therapy (Regimen 1, Course 1, Cycle A1;Regimen 1, Course 1, Cycle A2 (Days 22 - 42);Cycle B;Regimen 1, Course 2;Intrathecal Mafosfamide;Regimen 1 Course 2, IT mafosfamide;Regimen 2, Course 1;Regimen 2, Course, 1, Cycle C1;Regimen 2, Course 2
8	Endoscopic Third Ventriculostomy Versus Ventriculo-peritoneal Shunting in Idiopathic Normal Pressure Hydrocephalus	Recruiting	NCT03245138
9	Assessment of Cerebrospinal Fluid Flow Related Disorders Using a Phase-contrast Magnetic Resonance Imaging Technique.	Recruiting	NCT03656016
10	Multimodal Sonographic Monitoring of Cerebral Perfusion, Ventricle Seize and Optic Nerve Diameter During Weaning of Cerebrospinal Fluid Drainage Catheters: a Single Centre Observational Trial	Recruiting	NCT02408757
11	Lumbar Drainage Compared With Extraventricular Drainage of Cerebral Spinal Fluid in Treatment of Patients With Subarachnoid Hemorrhage - a Prospective Randomized Controlled Trial	Recruiting	NCT03065231
12	Evaluating Raised Intracranial Pressure Using MR Elastography	Active, not recruiting	NCT03096743
13	Endoscopic Intraventricular Hematoma Evacuation Surgery Versus External Ventricular Drainage for the Treatment of Patients With Moderate to Severe Intraventricular Hemorrhage: a Multicenter, Randomized, Controlled Trial	Not yet recruiting	NCT04037267
14	Hypothalamic-pituitary Effects After Endoscopic Third Ventriculostomy	Terminated	NCT01675037

Search NIH Clinical Center for Obstructive Hydrocephalus

Sources

Genetic Tests for Obstructive Hydrocephalus

Sources

Anatomical Context for Obstructive Hydrocephalus

MalaCards organs/tissues related to Obstructive Hydrocephalus:

⁴⁰

Brain, Pineal, Pituitary, Bone, Cerebellum, Spinal Cord, B Cells

Sources

Publications for Obstructive Hydrocephalus

Articles related to Obstructive Hydrocephalus:

(show top 50) (show all 1966)

#	Title	Authors	PMID	Year
1	Visual loss in tuberous sclerosis. ⁶¹ ⁵⁴	Dotan SA...Gebarski SS	1745348	1991
2	A case of developing obstructive hydrocephalus following aqueductal stenosis caused by developmental venous anomalies. ⁶¹	Higa N...Yoshimoto K	31907600	2020
3	Spontaneous Third Ventriculostomy in Krabbe Disease. ⁶¹	Zuccoli G...Escolar ML	32197817	2020
4	Aqueductal Compression by Dilated Virchow-Robin Spaces in the Mesencephalic-Pontine Region Presenting with Symptoms Mimicking Normal Pressure Hydrocephalus: A Case Report and Review of Literature. ⁶¹	Lo YT...Keong NCH	32200017	2020
5	Obstructive hydrocephalus due to aqueductal stenosis from developmental venous anomaly draining bilateral medial thalami: a case report. ⁶¹	Xian Z...Nakawah MO	32300468	2020
6	Pre-operative headaches and obstructive hydrocephalus predict an extended length of stay following suboccipital decompression for pediatric Chiari I malformation. ⁶¹	Elsamadicy AA...DiLuna M	32519127	2020
7	Risk Factors Portending Extended Length of Stay After Suboccipital Decompression for Adult Chiari I Malformation. ⁶¹	Elsamadicy AA...DiLuna M	32147550	2020
8	Biventricular hydrocephalus secondary to aqueductal developmental venous anomaly. ⁶¹	Low SYY...Seow WT	32295747	2020
9	Endoscopic Third Ventriculostomy in an Untreated Vein of Galen Malformation Presenting Lately with Acute Obstructive Hydrocephalus. ⁶¹	Sarica C...Baltacioglu F	32113993	2020
10	Flying with Colloid Cyst: A Cautionary Note. ⁶¹	Kutty RK...Peethambaran A	32001391	2020
11	Central neurocytoma originating in third ventricle with expansion into the cerebral aqueduct and fourth ventricle: Case report and review of literature. ⁶¹	Ferrigno BW...Killory BD	32502563	2020
12	Three-Dimensional Versus Two-Dimensional Endoscopic Third Ventriculostomy: Surgical Results Of A Preliminary Comparative Study. ⁶¹	de Notaris M...Catapano G	32497846	2020
13	Delayed extensive brain edema caused by the growth of a giant basilar apex aneurysm treated with basilar artery obliteration: a case report. ⁶¹	Garcia-Perez D...Alen JF	32505180	2020
14	Excision of a Retrochiasmatic Craniopharyngioma by Transcallosal, Interforniceal Approach With Exoscope Assistance: 2-Dimensional Operative Video. ⁶¹	Khatri D...Langer D	32497205	2020
15	Palliative ventriculoperitoneal shunting in dogs with obstructive hydrocephalus caused by tumors affecting the third ventricle. ⁶¹	Orlandi R...Mateo I	32472726	2020
16	The effect of mTOR inhibition on obstructive hydrocephalus in patients with tuberous sclerosis complex (TSC) related subependymal giant cell astrocytoma (SEGA). ⁶¹	Weidman DR...Bartels U	32285309	2020
17	"Two-Birds-One-Stone" Approach for Treating an Infant with Chiari I Malformation and Hydrocephalus: Is Cerebrospinal Fluid Diversion as Sole Treatment Enough? ⁶¹	Mathkour M...Bui CJ	32028005	2020
18	Too Much on Your "Plate"? Spectrum of Pathologies Involving the Tectal Plate. ⁶¹	Gandhi N...Torres C	32063011	2020
19	Spontaneous change in Density of colloid cyst - an unusual phenomenon. ⁶¹	K Kutty R...Peethambaran DA	32461180	2020
20	Acute Cerebellitis or Postinfectious Cerebellar Ataxia? Clinical and Imaging Features in Acute Cerebellitis. ⁶¹	Yildirim M...Anlar B	32160830	2020
21	An aggressive extension of dumbbell-type pediatric skull base meningioma: a case report with a review of literature. ⁶¹	Tsurubuchi T...Matsumura A	32371076	2020
22	Frame-Based Stereotactic Endoscopic Third Ventriculostomy-Toward Improved Precision and Minimizing Morbidities. ⁶¹	Chen CC...Warnke PC	32437981	2020
23	Trochlear Schwannoma Arising from Transition Zone of Nerve Sheath in the Pineal Region: Case Report and Review of the Literature. ⁶¹	Lan YH...Lu YJ	32059963	2020
24	Myxoid glioneuronal tumor, PDGFRA p.K385-mutant: clinical, radiologic, and histopathologic features. ⁶¹	Lucas CG...Solomon DA	31609499	2020
25	Hemorrhagic colloid cyst of the third ventricle: A rare cause of colloid cyst growth and progressive hydrocephalus. Case report. ⁶¹	Fernandez L...Elexpuru JA	32430243	2020
26	Iodine-123-Iomazenil SPECT Revealed Recovery of Neuronal Viability in Association with Improvement in Symptoms Following Treatment for Obstructive Hydrocephalus due to a Giant Posterior Cerebral Artery Aneurysm. ⁶¹	Horiuchi R...Kinouchi H	32084622	2020
27	Acute cerebellar edema after traumatic brain injury in a child. a case report. ⁶¹	Hejrati N...Soleman J	31758241	2020
28	Clinical Outcomes in Patients with Renal Cell Carcinoma Metastases to the Choroid Plexus. ⁶¹	Crisman CM...Moss NS	32251814	2020
29	High Prevalence of Developmental Venous Anomaly in Diffuse Intrinsic Pontine Gliomas: A Pediatric Control Study. ⁶¹	Roux A...Varlet P	31342064	2020
30	Anaesthetic management of intracranial hypertension and pregnancy. A case report. ⁶¹	Sampaio A...Orfao R	32192721	2020
31	Design and validation of a 3D-printed simulator for endoscopic third ventriculostomy. ⁶¹	Zhu J...Ma C	31712902	2020
32	Obstructive Hydrocephalus in the Differential Diagnosis of Early Adolescent Depression. ⁶¹	Zarkar S...Coffey BJ	32125901	2020
33	ETV in infancy and childhood below 2 years of age for treatment of hydrocephalus. ⁶¹	El Damaty A...Schroeder HWS	32222800	2020
34	A primary third ventricle mixed germ cell tumor with leptomeningeal dissemination of immature teratoma component. ⁶¹	Demir MK...Seker A	31418081	2020
35	Postoperative Tetraplegia to a Child after Cerebellar Pilocytic Astrocytoma Excision at Prone Position: Case Report and Literature Review. ⁶¹	Panagopoulos D...Themistocleous M	32161253	2020
36	[Analysis of misdiagnosis causes of suprasellar arachnoid cysts]. ⁶¹	Qu Z...Ni HT	32164116	2020
37	A rare case of intralesional haemorrhage of a benign aqueductal cyst after CSF diversion treatment. A case report and review of literature. ⁶¹	Biju RD...Muthu T	32202165	2020
38	Neocortical tissue recovery in severe congenital obstructive hydrocephalus after intraventricular administration of bone marrow-derived mesenchymal stem cells. ⁶¹	Garcia-Bonilla M...Jimenez AJ	32183876	2020
39	Provider views on perioperative steroid use for patients with newly diagnosed pediatric brain tumors. ⁶¹	Malbari F...Levy AS	32026434	2020
40	Endoscopic-assisted surgery versus microsurgery for pineal region tumors: a single-center retrospective study. ⁶¹	Xin C...Chen J	32198566	2020
41	Overshunting-Associated Myelopathy Treated with Endoscopic Third Ventriculostomy. ⁶¹	Ko Y...Nakase H	31704357	2020
42	Obstruction of Ventriculoperitoneal Shunt After Myelography-Report of a Unique Case and Its Treatment. ⁶¹	Silva NA...Goldstein IM	31756508	2020
43	Second Window Indocyanine Green (SWIG) Near Infrared Fluorescent Transventricular Biopsy of Pineal Tumor. ⁶¹	Cho A...Lee JYK	31669685	2020
44	Letter to the Editor Regarding "Surgical Techniques and Long-term Outcomes of Flexible Neuroendoscopic Aqueductoplasty and Stenting in Infants with Obstructive Hydrocephalus: A Single-center Study". ⁶¹	Goel A	32059271	2020
45	Post-shunting corpus callosal signal change and review of the literature. ⁶¹	Su S...Gaillard F	31874812	2020
46	Ruptured Tentorial Arteriovenous Fistula: Endoscopic-Assisted Microsurgical Disconnection Using Indocyanine Green Videoangiography Guidance. ⁶¹	Messina R...Signorelli F	31726094	2020
47	Occipitocervical fusion complicated with cerebellar abscess: a case report. ⁶¹	Lee CC...Liu YT	32111221	2020
48	Unexpected phenotype in a frameshift mutation of PTCH1. ⁶¹	Beltrami B...Milani D	31578813	2020
49	Magnetic Resonance Imaging Findings in 13 Neurologic Pot-Bellied Pigs. ⁶¹	Castel A...Hecht S	32076601	2020
50	ETV for successful treatment of holocord syrinx with hydrocephalus: a case report. ⁶¹	Rose L...Sinha S	31994420	2020

Sources

Genes for Obstructive Hydrocephalus

Genes related to Obstructive Hydrocephalus (0 elite genes):

(show all 21)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	FOXJ1	Forkhead Box J1	Protein Coding	13.58	DISEASES inferred ¹⁵ GeneCards inferred via : Disorders (show sections)
2	AQP1	Aquaporin 1 (Colton Blood Group)	Protein Coding	12.54	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
3	PRL	Prolactin	Protein Coding	11.51	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
4	TSC1	TSC Complex Subunit 1	Protein Coding	8.82	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁴	1745348
5	RNU4ATAC	RNA, U4atac Small Nuclear (U12-Dependent Splicing)	RNA Gene	7.6	DISEASES inferred ¹⁵ ¹⁵
6	AQP4	Aquaporin 4	Protein Coding	6.78	DISEASES inferred ¹⁵
7	SYP	Synaptophysin	Protein Coding	6.68	DISEASES inferred ¹⁵
8	CRLF1	Cytokine Receptor Like Factor 1	Protein Coding	6.49	DISEASES inferred ¹⁵
9	GFAP	Glial Fibrillary Acidic Protein	Protein Coding	6.25	DISEASES inferred ¹⁵
10	CCDC85C	Coiled-Coil Domain Containing 85C	Protein Coding	6.15	DISEASES inferred ¹⁵
11	NF1	Neurofibromin 1	Protein Coding	6.09	DISEASES inferred ¹⁵
12	ZIC3	Zic Family Member 3	Protein Coding	5.99	DISEASES inferred ¹⁵
13	AFP	Alpha Fetoprotein	Protein Coding	5.84	DISEASES inferred ¹⁵
14	PLAT	Plasminogen Activator, Tissue Type	Protein Coding	5.8	DISEASES inferred ¹⁵
15	OLIG2	Oligodendrocyte Transcription Factor 2	Protein Coding	5.64	DISEASES inferred ¹⁵
16	NF2	Neurofibromin 2	Protein Coding	5.62	DISEASES inferred ¹⁵
17	PLG	Plasminogen	Protein Coding	5.62	DISEASES inferred ¹⁵
18	ENO2	Enolase 2	Protein Coding	5.58	DISEASES inferred ¹⁵
19	RICTOR	RPTOR Independent Companion Of MTOR Complex 2	Protein Coding	5.53	DISEASES inferred ¹⁵
20	TSC2	TSC Complex Subunit 2	Protein Coding	5.49	DISEASES inferred ¹⁵
21	MPDZ	Multiple PDZ Domain Crumbs Cell Polarity Complex Component	Protein Coding	5.48	DISEASES inferred ¹⁵

Sources

Variations for Obstructive Hydrocephalus

Sources

Expression for Obstructive Hydrocephalus

Search GEO for disease gene expression data for Obstructive Hydrocephalus.

Sources

Pathways for Obstructive Hydrocephalus

Pathways related to Obstructive Hydrocephalus according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Regulation of lipid metabolism Insulin signaling-generic cascades ²² Show member pathways acetyl-CoA biosynthesis from citrate ¹ Butyrate-induced histone acetylation ¹ Cell adhesion PLAU signaling ²² Class IB PI3K non-lipid kinase events ¹ Development CNTF receptor signaling ²² Development Growth hormone signaling via PI3K/AKT and MAPK cascades ²² ErbB2/ErbB3 signaling events ¹ Glucose Homeostasis ¹ Insulin signaling pathway ³⁶ IRS activation ⁶⁵ Signal attenuation ⁶⁵ Transcription Receptor-mediated HIF regulation ²² Translation Regulation of EIF2 activity ²² Translation Regulation of EIF4F activity ²² Translation Insulin regulation of translation ²²	12.21	TSC2 TSC1 PLG PLAT NF2 CRLF1
2	Neuroscience ⁴	12.09	SYP NF2 NF1 GFAP ENO2
3	Neural Stem Cells and Lineage-specific Markers ⁶⁴	11.4	SYP OLIG2 GFAP
4	mTOR signaling pathway (Pathway Interaction Database) ¹	11.21	TSC2 TSC1 RICTOR
5	Glioblastoma Multiforme ⁶³	10.97	TSC2 TSC1 NF2 NF1
6	Dissolution of Fibrin Clot ⁶⁵	10.48	PLG PLAT

Sources

GO Terms for Obstructive Hydrocephalus

Cellular components related to Obstructive Hydrocephalus according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	apical part of cell	GO:0045177	9.43	PLAT NF2 AQP1
2	Schaffer collateral - CA1 synapse	GO:0098685	9.33	SYP PLG PLAT
3	astrocyte end-foot	GO:0097450	8.96	GFAP AQP4
4	TSC1-TSC2 complex	GO:0033596	8.62	TSC2 TSC1

Biological processes related to Obstructive Hydrocephalus according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	negative regulation of cell proliferation	GO:0008285	9.55	TSC2 TSC1 PLG NF2 NF1
2	negative regulation of protein kinase activity	GO:0006469	9.54	TSC2 NF2 NF1
3	cerebral cortex development	GO:0021987	9.5	TSC1 NF1 CCDC85C
4	regulation of cell-matrix adhesion	GO:0001952	9.4	TSC1 NF1
5	multicellular organismal water homeostasis	GO:0050891	9.26	AQP4 AQP1
6	cellular water homeostasis	GO:0009992	8.96	AQP4 AQP1
7	trans-synaptic signaling by BDNF, modulating synaptic transmission	GO:0099183	8.62	PLG PLAT

Molecular functions related to Obstructive Hydrocephalus according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	water channel activity	GO:0015250	8.62	AQP4 AQP1

Sources

Sources for Obstructive Hydrocephalus

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia