MCID: OBS001
MIFTS: 52

Obstructive Jaundice

Categories: Gastrointestinal diseases, Genetic diseases

Aliases & Classifications for Obstructive Jaundice

MalaCards integrated aliases for Obstructive Jaundice:

Name: Obstructive Jaundice 12 15
Jaundice, Obstructive 44 73
Obstructive Hyperbilirubinemia 12
Cholestatic Jaundice Syndrome 12
Cholestatic Jaundice 12
Jaundice Obstructive 55
Jaundice Cholestatic 55

Classifications:



External Ids:

Disease Ontology 12 DOID:13603
MeSH 44 D041781
NCIt 50 C34742
UMLS 73 C0022354

Summaries for Obstructive Jaundice

MalaCards based summary : Obstructive Jaundice, also known as jaundice, obstructive, is related to cholecystitis and abdominal tuberculosis, and has symptoms including icterus and jaundice (not of newborn). An important gene associated with Obstructive Jaundice is ALPP (Alkaline Phosphatase, Placental), and among its related pathways/superpathways are IL-1 Family Signaling Pathways and Folate Metabolism. The drugs Lactulose and Ceftriaxone have been mentioned in the context of this disorder. Affiliated tissues include liver, pancreas and lung, and related phenotypes are growth/size/body region and homeostasis/metabolism

Related Diseases for Obstructive Jaundice

Diseases in the Obstructive Jaundice family:

Jaundice, Familial Obstructive, of Infancy

Diseases related to Obstructive Jaundice via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 410)
# Related Disease Score Top Affiliating Genes
1 cholecystitis 30.6 ALB F2 GPT
2 abdominal tuberculosis 30.5 ALB F2
3 hepatitis 30.4 F2 GGT1 GPT SLC17A5 TNF
4 fascioliasis 29.9 ALB ALPP GPT SLC17A5
5 cholangiocarcinoma 29.9 ALB GGT1 HGF IL6
6 biliary atresia 29.8 ALB GPT HGF
7 hepatorenal syndrome 29.8 ALB EDN1 F2 REN
8 prostatitis 29.3 CXCL8 IL6 TNF
9 gastroenteritis 29.3 ALB CXCL8 IL6 TNF
10 monocytic leukemia 29.2 CXCL8 IL6 TNF
11 choledocholithiasis 29.2 ALB ALPP F2 GPT SLC17A5
12 portal hypertension 29.2 ALB EDN1 F2 GPT TNF
13 diabetes mellitus 29.1 ALB EDN1 IL6 REN TNF
14 sclerosing cholangitis 29.1 ALB GGT1 GPBAR1 TNF
15 hepatic tuberculosis 29.1 ALB ALPP F2 GGT1 GPT
16 clonorchiasis 29.0 CD79A CXCL8 TNF
17 ulcerative colitis 29.0 CXCL8 IL6 TNF
18 cholestasis 28.9 ALPP F2 GGT1 GPT SLC25A13
19 biliary tract disease 28.5 ALB F2 GGT1 GPBAR1 SLC25A13
20 cholangitis 28.4 ALB F2 GGT1 GPBAR1 GPT IL6
21 peritonitis 28.3 ALB CXCL8 F2 IL6 TNF
22 hepatocellular carcinoma 28.0 ALB CXCL8 F2 GGT1 HGF IL6
23 myeloma, multiple 27.7 ALB CD79A CXCL8 HGF IL6 TNF
24 liver disease 27.5 ALB F2 GGT1 GPT HGF SLC17A5
25 liver cirrhosis 27.5 ALB EDN1 F2 GGT1 GPT HGF
26 mirizzi syndrome 11.2
27 biliary malformation with renal tubular insufficiency 11.2
28 cholestasis, benign recurrent intrahepatic, 1 11.2
29 acth deficiency, isolated 11.0
30 cholestasis, benign recurrent intrahepatic, 2 11.0
31 bile acid synthesis defect, congenital, 1 11.0
32 congenital disorder of glycosylation, type ik 11.0
33 paraquat poisoning 11.0 GPT SLC17A5
34 acute adrenal insufficiency 10.9 IL6 REN
35 pyridoxine deficiency 10.9 GPT SLC17A5
36 paramyloidosis 10.9 ALB TTR
37 scorpion envenomation 10.9 IL6 TNF
38 benign essential hypertension 10.8 ALB REN
39 leukomalacia 10.8 IL6 TNF
40 angioimmunoblastic lymphadenopathy with dysproteinemia 10.8 IL6 TNF
41 alkaline phosphatase, plasma level of, quantitative trait locus 1 10.8 ALPP GGT1
42 antipyrine metabolism 10.8 ALB F2
43 non-a-e hepatitis 10.8 ALB F2
44 kidney papillary necrosis 10.8 ALB REN
45 malignant renovascular hypertension 10.8 EDN1 REN
46 hepatoportal sclerosis 10.8 F2 GPT
47 sudden sensorineural hearing loss 10.7 F2 IL6
48 null-cell leukemia 10.7 IL6 TNF
49 primary hepatic neuroendocrine carcinoma 10.7 ALPP GPT
50 intestinal impaction 10.7 F2 REN

Graphical network of the top 20 diseases related to Obstructive Jaundice:



Diseases related to Obstructive Jaundice

Symptoms & Phenotypes for Obstructive Jaundice

UMLS symptoms related to Obstructive Jaundice:


icterus, jaundice (not of newborn)

MGI Mouse Phenotypes related to Obstructive Jaundice:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.96 EDN1 F2 GGT1 GPBAR1 HGF IL6
2 homeostasis/metabolism MP:0005376 9.93 EDN1 TTR F2 GGT1 GPBAR1 IL6
3 liver/biliary system MP:0005370 9.5 GPBAR1 HGF IL6 ALB SLC25A13 CD79A
4 renal/urinary system MP:0005367 9.23 GGT1 GPBAR1 IL6 REN ALB SLC25A13

Drugs & Therapeutics for Obstructive Jaundice

Drugs for Obstructive Jaundice (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 81)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lactulose Approved Phase 4 4618-18-2 11333
2
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
3
Ofloxacin Approved Phase 4 82419-36-1 4583
4
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
5 Renal Agents Phase 4
6 Cytochrome P-450 CYP1A2 Inhibitors Phase 4
7 Cytochrome P-450 Enzyme Inhibitors Phase 4
8 Topoisomerase Inhibitors Phase 4
9 Anti-Bacterial Agents Phase 4,Not Applicable
10 Antibiotics, Antitubercular Phase 4,Not Applicable
11 Anti-Infective Agents Phase 4,Not Applicable
12 Antitubercular Agents Phase 4
13
Simvastatin Approved Phase 3 79902-63-9 54454
14
Ezetimibe Approved Phase 3 163222-33-1 150311
15
Trioxsalen Approved Phase 2, Phase 3,Not Applicable 3902-71-4 5585
16
Nicotinamide Approved, Investigational, Nutraceutical Phase 3 98-92-0 936
17
Niacin Approved, Investigational, Nutraceutical Phase 3 59-67-6 938
18
Methionine Approved, Nutraceutical Phase 3 63-68-3 6137
19
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
20 Atorvastatin Calcium Phase 3 134523-03-8
21 Rosuvastatin Calcium Phase 3 147098-20-2
22 Hematoporphyrin Derivative Phase 2, Phase 3,Not Applicable
23 Nicotinic Acids Phase 3
24 Dihematoporphyrin Ether Phase 2, Phase 3,Not Applicable
25 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 3
26 Hypolipidemic Agents Phase 3
27 Vitamins Phase 3
28 Anticholesteremic Agents Phase 3
29 Lipid Regulating Agents Phase 3
30 Antimetabolites Phase 3
31 Calcium, Dietary Phase 3
32 Micronutrients Phase 3
33 Trace Elements Phase 3
34 Vasodilator Agents Phase 3
35 Vitamin B Complex Phase 3
36 Pharmaceutical Solutions Phase 3
37 Vitamin B3 Nutraceutical Phase 3
38 Folate Nutraceutical Phase 3
39 Vitamin B9 Nutraceutical Phase 3
40
Menthol Approved Phase 2 2216-51-5 16666
41
Ursodeoxycholic acid Approved, Investigational Phase 2 128-13-2 31401
42
Neostigmine Approved, Vet_approved Phase 1, Phase 2 59-99-4 4456
43
Pancrelipase Approved, Investigational Phase 2,Phase 1 53608-75-6
44 pancreatin Phase 2,Phase 1
45
Bilirubin Phase 2,Phase 1 635-65-4 5280352
46 Cholagogues and Choleretics Phase 2
47 Cholinergic Agents Phase 1, Phase 2
48 Cholinesterase Inhibitors Phase 1, Phase 2
49 Gastrointestinal Agents Phase 2
50 Neurotransmitter Agents Phase 1, Phase 2,Not Applicable

Interventional clinical trials:

(show top 50) (show all 60)
# Name Status NCT ID Phase Drugs
1 Randomised Trial Comparing Metal and Plastic Biliary Stents Stents for Palliating Malignant Jaundice Unknown status NCT00731419 Phase 4
2 Human Kidney Histopathology in Obstructive Jaundice Completed NCT01090193 Phase 4
3 Covered vs. Uncovered SEMS for Occluded Biliary Metal Stents Completed NCT01315522 Phase 4
4 Antibiotics to Decrease Post ERCP Cholangitis Recruiting NCT03087656 Phase 4 Ceftriaxone;Levofloxacin
5 Preoperative Biliary Drainage for the Lower Malignant Obstructive Jaundice Unknown status NCT01744938 Phase 3
6 Palliative Biliary Stenting on the Quality of Life of Patients With Unresectable Carcinoma Gallbladder With Hiliar Block. Completed NCT00391183 Phase 2, Phase 3
7 A Clinical Trial to Assess the Efficacy and Safety of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-383) Completed NCT02550288 Phase 3 Ezetimibe 10 mg;Atorvastatin 10 mg;Placebo for Ezetimibe 10 mg tablet;Placebo for Atorvastatin 10 mg capsule
8 A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-384) Completed NCT02460159 Phase 3 EZ 10 mg/Atorva 20 mg FDC;EZ 10 mg/Atorva 10 mg FDC
9 A Study of the Efficacy and Safety of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-832) Completed NCT02741245 Phase 3 Ezetimibe 10 mg;Rosuvastatin 2.5 mg;Placebo for Ezetimibe;Placebo for Rosuvastatin
10 MK-0524B Lipid Study (MK-0524B-063) Completed NCT00479882 Phase 3 Comparator: simvastatin;MK-0524A;Placebo;MK-0524B
11 Lipid Efficacy and Safety in Participants With Mixed Hyperlipidemia (MK-0524B-024) Completed NCT00289900 Phase 3 MK-0524A;Atorvastatin;Simvastatin
12 Photodynamic Therapy (PDT) for Palliation of Cholangiocarcinoma Recruiting NCT01755013 Phase 2, Phase 3
13 Remaxol® in Mechanical Jaundice of Non-malignant Origin Active, not recruiting NCT03418935 Phase 3 Remaxol (succinate + methionine + inosine + nicotinamide);Ringer's Solution
14 Remaxol® in Malignant Mechanical Jaundice Active, not recruiting NCT03416062 Phase 3 Remaxol®;Ringer's Solution
15 A Study to Evaluate Efficacy and Safety of Extended-Release Niacin + Laropiprant + Simvastatin in Participants With Primary Hypercholesterolemia or Mixed Dyslipidemia (MK-0524B-118) Terminated NCT01294683 Phase 3 Simvastatin;Extended Release (ER) niacin/laropiprant/simvastatin (N/LRPT/SIM);Extended Release (ER) niacin/laropiprant (N/LRPT);Placebo
16 Comparison Between Two Methods of Bilateral Stenting for Malignant Hilar Obstruction Withdrawn NCT01622803 Phase 3
17 The Effect of Ursodeoxycholic Acid in Liver Functional Restoration of Patients With Obstructive Jaundice Unknown status NCT01688375 Phase 2 Ursodeoxycholic Acid
18 Role of Endoscopic RFA in Prolonging the Patency of Metal Stents in Patients With Malignant Obstructive Jaundice Unknown status NCT01275768 Phase 1, Phase 2
19 Cholinergic Anti-inflammatory Pathway in Prevention & Treatment of the SIRS in Patients With Jaundice After Operation. Unknown status NCT02279147 Phase 1, Phase 2 neostigmine methylsulfate,raceanisodamine hydrochloride
20 Evaluation of Preoperative Biliary Drainage Before Pancreatoduodenectomy Unknown status NCT01941342 Phase 2
21 Metal or Plastic Stents to Relieve Obstruction of Obstructive Jaundice Prior to Resection of Periampullary Tumors. Completed NCT02166840 Phase 2
22 Radiofrequency Ablation for Biliopancreatic Malignancy Completed NCT02468076 Phase 2
23 SMOFlipid to Lessen the Severity of Neonatal Cholestasis Terminated NCT02721277 Phase 1, Phase 2 SMOFlipid
24 C-VISA BikDD: Liposome in Advanced Pancreatic Cancer Withdrawn NCT00968604 Phase 1
25 Immune Function in Patients With Obstructive Jaundice Unknown status NCT01367821
26 Percutaneous Transhepatic Cholangiography Versus Endoscopic Ultrasound Guided Biliary Drainage Unknown status NCT01686425 Not Applicable
27 Efficacy and Safety of Endobiliary Radiofrequency Ablation by Using a Novel RF Catheter (ELRA®) on Maintaining the Patency of Endobiliary Metal Drainage in Patients With Malignant Biliary Strictures : A Double-arm Comparable Study Unknown status NCT02646514 Not Applicable
28 Intra-luminal Radiofrequency Ablation for Inoperable Malignant Biliary Stenosis Unknown status NCT02841800 Not Applicable
29 Evaluation of Immune Function in Biliary Atresia Children With Prolonged Jaundice Unknown status NCT00155194
30 Application of n-3 Fatty to Patient of Jaundice Completed NCT03376945 trail cohort;control cohort
31 Comparison Between Internal and External Preoperative Biliary Drainage in Periampullary Cancers Completed NCT01134276 Not Applicable
32 Safety and Efficacy of Photodynamic Therapy for Bile Duct Invasion of Hepatocellular Carcinoma Completed NCT01506115 Not Applicable Photofrin
33 Endoscopic Versus Percutaneous Drainage For Hilar Block in Gall Bladder Cancer Completed NCT00409864 Not Applicable
34 Outcome of Carbon Dioxide Versus Air Insufflations During Endoscopic Retrograde Cholangiopancreatography (ERCP) Completed NCT01321203
35 Endoscopic Ultrasound-guided Biliary Drainage for Malignant Biliary Obstruction After Failed ERCP Completed NCT03510754
36 Malignant Obstruction ZILVER Against Routine Therapy (MOZART I) Completed NCT00196105 Not Applicable
37 Biliary Atresia, Hepatic Buffer Response and Sevoflurane Completed NCT02471209 Sevoflurane
38 Early Versus Late Cholecystectomy After Clearance of Common Bile Duct Stones Completed NCT02460315 Not Applicable
39 Endoscopic Retrograde Cholangiopancreatography (ERCP) Based Sampling of Indeterminate Bile Duct Strictures Completed NCT01580709 Not Applicable
40 Biliary Cannulation During Endoscopic Retrograde Cholangiopancreatography: Precut Versus Conventional Cannulation Completed NCT02477228 Not Applicable
41 Treatment of Obstructive Jaundice in Autoimmune Pancreatitis and/or Immunoglobulin G4-related Sclerosing Cholangitis by Corticosteroids Recruiting NCT02797665 Not Applicable corticosteroids
42 Pre-treatment With Methylene Blue Prevent Peri-operative Reduced Systemic Vascular Resistance Recruiting NCT03406676 Not Applicable Methylene Blue
43 EUS Evaluation of CBD Diameter in Malignant Obstructive Jaundice Recruiting NCT03494023
44 Comparison of Metal and Plastic Stents for Preoperative Biliary Decompression Recruiting NCT01191814 Not Applicable
45 Cholangioscopic Assessment of Occluded Biliary Stent and Role of Biliary Radiofrequency Ablation Recruiting NCT03133026 Not Applicable
46 Trial Comparing Metal Versus Plastic Stents for Preoperative Biliary Decompression Recruiting NCT01675908 Not Applicable
47 Efficacy of Partial Covered Double Bare Metal Stent Compared to Uncovered Double Bare Metal Stent in Malignant Biliary Obstruction Recruiting NCT02937246 Not Applicable
48 RFA RCT for Pancreatic or Bile Duct Cancer Recruiting NCT02166190 Not Applicable
49 Study of Abdominal Drainage in LCBDE+PC Recruiting NCT03120754 Not Applicable
50 The Necessity of Bile Cultures in Patients With Acute Cholangitis Recruiting NCT02601417 Not Applicable

Search NIH Clinical Center for Obstructive Jaundice

Cochrane evidence based reviews: jaundice, obstructive

Genetic Tests for Obstructive Jaundice

Anatomical Context for Obstructive Jaundice

MalaCards organs/tissues related to Obstructive Jaundice:

41
Liver, Pancreas, Lung, Kidney, Brain, Lymph Node, Myeloid

Publications for Obstructive Jaundice

Articles related to Obstructive Jaundice:

(show top 50) (show all 767)
# Title Authors Year
1
A Case of Eosinophilic Gastroenteritis in Which Obstructive Jaundice Developed due to Invagination of the Duodenal Wall. ( 29434146 )
2018
2
Obstructive jaundice as primary presentation of a stage IIE Non-Hodgkin lymphoma: A decision making process between advanced lymphoma and locally advanced/metastatic pancreatic adenocarcinoma. ( 29547849 )
2018
3
Efficacy of<sup>125</sup>I Versus Non-<sup>125</sup>I Combined with Transcatheter Arterial Chemoembolization for the Treatment of Unresectable Hepatocellular Carcinoma with Obstructive Jaundice. ( 29305738 )
2018
4
A Surgically Resected Pancreatic Schwannoma with Obstructive Jaundice with Special Reference to Differential Diagnosis from Other Cystic Lesions in the Pancreas. ( 29606941 )
2018
5
Hepatobiliary and Pancreatic: Rare cause of obstructive jaundice by Trichosporon asahii. ( 29372610 )
2018
6
A Systematic Review and Meta-analysis of Intraluminal Brachytherapy Versus Stent Alone in the Treatment of Malignant Obstructive Jaundice. ( 29075881 )
2018
7
A patient with abdominal pain and obstructive jaundice. ( 29749334 )
2018
8
Post-operative care of interventional therapy for 40 liver cancer patients with obstructive jaundice. ( 29767833 )
2018
9
Elevated endogenous opioids in obstructive jaundice: The possible skin mechanisms. ( 29857894 )
2018
10
MicroRNA-29a mitigation of endoplasmic reticulum and autophagy aberrance counteracts in obstructive jaundice-induced fibrosis in mice. ( 29105510 )
2018
11
Spontaneous remission of obstructive jaundice in rats: Selection of experimental models. ( 29904412 )
2018
12
Pancreatic Burkitt's lymphoma presenting as an unusual cause of obstructive jaundice. ( 29696783 )
2018
13
Bile and circulating HMGB1 contributes to systemic inflammation in obstructive jaundice. ( 29907203 )
2018
14
Obstructive jaundice caused by an adenoma of the common hepatic duct. ( 29980303 )
2018
15
MicroRNA-29a mitigation of toll-like receptor 2 and 4 signaling and alleviation of obstructive jaundice-induced fibrosis in mice. ( 29366780 )
2018
16
Combined Effectiveness of Honey and Immunonutrition on Bacterial Translocation Secondary to Obstructive Jaundice in Rats: Experimental Study. ( 29786675 )
2018
17
Primary pancreatic lymphoma as a cause of obstructive jaundice. ( 29615287 )
2018
18
Pancreatobiliary fistula associated with intraductal papillary mucinous carcinoma accompanying obstructive jaundice: A case report. ( 29890488 )
2018
19
The Effect of Calcium Dobesilate on Liver Damage in Experimental Obstructive Jaundice. ( 29589984 )
2018
20
Duodenal mucinous adenocarcinoma presenting as ileus, obstructive jaundice and massive ascites: A case report. ( 29456851 )
2018
21
Malignant obstructive jaundice treated with intraluminal placement of Iodine-125 seed strands and metal stents: An analysis of long-term outcomes and prognostic features. ( 29748084 )
2018
22
Spironolactone rescues renal dysfunction in obstructive jaundice rats by upregulating ACE2 expression. ( 29882088 )
2018
23
Comparison of Endoscopic Ultrasonography Guided Biliary Drainage and Percutaneous Transhepatic Biliary Drainage in the Management of Malignant Obstructive Jaundice After Failed ERCP: Erratum. ( 29613967 )
2018
24
Pathophysiological consequences of obstructive jaundice and perioperative management. ( 29428098 )
2018
25
Identification of bile survivin and carbohydrate antigen 199 in distinguishing cholangiocarcinoma from benign obstructive jaundice. ( 27874286 )
2017
26
Magnetic Resonance Cholangiopancreatography (MRCP) Evaluation of Obstructive Jaundice in Comparison with Endoscopic Retrograde Cholangiopancreatography (ERCP). ( 28588181 )
2017
27
Cholangiohydatidosis: an Infrequent Cause of Obstructive Jaundice and Acute Cholangitis. ( 28425414 )
2017
28
An HIV-positive Case of Obstructive Jaundice Caused by Immune Reconstitution Inflammatory Syndrome of Tuberculous Lymphadenitis Successfully Treated with Corticosteroids. ( 28883243 )
2017
29
Comparison of Endoscopic Ultrasonography Guided Biliary Drainage and Percutaneous Transhepatic Biliary Drainage in the Management of Malignant Obstructive Jaundice After Failed ERCP. ( 29206804 )
2017
30
Von Meyenburg complexes in a patient with obstructive jaundice. ( 28899322 )
2017
31
Pseudohyponatraemia secondary to hyperlipidaemia in obstructive jaundice. ( 29196308 )
2017
32
Clinical Study on Using (125)I Seeds Articles Combined with Biliary Stent Implantation in the Treatment of Malignant Obstructive Jaundice. ( 28739766 )
2017
33
A new intraductal radiofrequency ablation device for inoperable biliopancreatic tumors complicated by obstructive jaundice: the IGNITE-1 study. ( 28732391 )
2017
34
A simple rat model of in situ reversible obstructive jaundice in situ reversible obstructive jaundice model. ( 28580342 )
2017
35
Clinical Interpretation of Elevated CA 19-9 Levels in Obstructive Jaundice Following Benign and Malignant Pancreatobiliary Disease. ( 28830135 )
2017
36
Embryonal rhabdomyosarcoma of the biliary tree: A rare cause of obstructive jaundice in children which can mimic choledochal cysts. ( 29089679 )
2017
37
Lemmel's syndrome: Obstructive jaundice secondary to a duodenal diverticulum. ( 28341217 )
2017
38
Primary extrahepatic bile duct neuroendocrine tumor with obstructive jaundice masquerading as a Klatskin tumor. ( 28596824 )
2017
39
A late unusual complication after an open cholecystectomy: Amputation neuroma of the CBD causing obstructive jaundice. ( 28837915 )
2017
40
Altered expression of differential gene and lncRNA in the lower thoracic spinal cord on different time courses of experimental obstructive jaundice model accompanied with altered peripheral nociception in rats. ( 29285317 )
2017
41
Obstructive Jaundice Caused by Hepatic Torsion in an Infant with Congenital Diaphragmatic Hernia. ( 28082781 )
2017
42
Endoscopic ultrasound-guided choledochoduodenostomy for obstructive jaundice with venous collaterals around the bile duct wall (with video). ( 28440241 )
2017
43
Fine-needle aspiration findings of a rare hematopoietic neoplasm presenting as obstructive jaundice. ( 28752676 )
2017
44
Comparison of efficacy and complications of endoscopic and percutaneous biliary drainage in malignant obstructive jaundice: a systematic review and meta-analysis. ( 29037223 )
2017
45
Preventing oxygen free radical damage by proanthocyanidin in obstructive jaundice. ( 28740952 )
2017
46
Autoimmune Hemolytic Anemia Obscured by the Obstructive Jaundice Associated with IgG4-related Sclerosing Cholangitis in a Patient with Type 1 Autoimmune Pancreatitis: A Case Report and Review of the Literature. ( 29269682 )
2017
47
Effects of Different Palliative Jaundice Reducing Methods on Immunologic Functions in Patients with Advanced Malignant Obstructive Jaundice. ( 28739769 )
2017
48
Advanced Roux-en-Y hepaticojejunostomy with magnetic compressive anastomats in obstructive jaundice dog models. ( 28779259 )
2017
49
Obstructive Jaundice Caused by Heterotopic Pancreas. ( 29215624 )
2017
50
My First Patient: More Than Obstructive Jaundice. ( 28027099 )
2017

Variations for Obstructive Jaundice

Expression for Obstructive Jaundice

Search GEO for disease gene expression data for Obstructive Jaundice.

Pathways for Obstructive Jaundice

Pathways related to Obstructive Jaundice according to GeneCards Suite gene sharing:

(show all 18)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.02 CXCL8 EDN1 IL6 TNF
2
Show member pathways
11.89 ALB F2 GGT1 IL6 TNF
3 11.83 CXCL8 IL6 TNF
4 11.83 ALB ALPP HGF IL6
5 11.81 CD79A IL6 TNF
6 11.77 EDN1 IL6 TNF
7 11.73 CXCL8 HGF IL6 TNF
8 11.71 CXCL8 IL6 TNF
9 11.67 CXCL8 IL6 TNF
10 11.62 CXCL8 EDN1 IL6 TNF
11 11.58 CXCL8 IL6 TNF
12
Show member pathways
11.49 CXCL8 IL6 TNF
13 11.41 CXCL8 IL6 TNF
14 11.32 CXCL8 IL6 TNF
15 11.25 ALB F2 TTR
16 10.95 CXCL8 HGF IL6 TNF
17 10.82 CXCL8 EDN1 HGF IL6 TNF
18 10.71 CXCL8 IL6 TNF

GO Terms for Obstructive Jaundice

Cellular components related to Obstructive Jaundice according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 ALB CXCL8 EDN1 F2 HGF IL6
2 extracellular space GO:0005615 9.36 ALB CXCL8 EDN1 F2 GGT1 GPT

Biological processes related to Obstructive Jaundice according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.62 CXCL8 HGF IL6 TNF
2 positive regulation of DNA binding transcription factor activity GO:0051091 9.54 EDN1 IL6 TNF
3 cellular protein metabolic process GO:0044267 9.46 ALB F2 IL6 TTR
4 embryonic digestive tract development GO:0048566 9.4 CXCL8 TNF
5 negative regulation of lipid storage GO:0010888 9.26 IL6 TNF
6 regulation of signaling receptor activity GO:0010469 9.17 CXCL8 EDN1 F2 HGF IL6 TNF
7 positive regulation of smooth muscle cell proliferation GO:0048661 9.13 EDN1 IL6 TNF

Molecular functions related to Obstructive Jaundice according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.92 CXCL8 EDN1 IL6 TNF

Sources for Obstructive Jaundice

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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