Obstructive Jaundice

Categories: Gastrointestinal diseases, Genetic diseases
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Aliases & Classifications for Obstructive Jaundice

MalaCards integrated aliases for Obstructive Jaundice:

Name: Obstructive Jaundice 11 14 16
Jaundice, Obstructive 43 71
Obstructive Hyperbilirubinemia 11
Cholestatic Jaundice Syndrome 11
Cholestatic Jaundice 11
Jaundice Obstructive 53
Jaundice Cholestatic 53


External Ids:

Disease Ontology 11 DOID:13603
MeSH 43 D041781
NCIt 49 C34742
SNOMED-CT 68 59848001
UMLS 71 C0022354

Summaries for Obstructive Jaundice

Disease Ontology: 11 A cholestasis characterized by yellowish pigmentation of the skin and sclera due to high bilirubin levels resulting from biliary tract obstruction.

MalaCards based summary: Obstructive Jaundice, also known as jaundice, obstructive, is related to cholestasis and cholangiocarcinoma, and has symptoms including icterus and jaundice (not of newborn). An important gene associated with Obstructive Jaundice is ALPP (Alkaline Phosphatase, Placental), and among its related pathways/superpathways is FOXA2 and FOXA3 transcription factor networks. The drugs Lactulose and Nicotinamide have been mentioned in the context of this disorder. Affiliated tissues include liver, skin and pancreas, and related phenotypes are renal/urinary system and homeostasis/metabolism

Related Diseases for Obstructive Jaundice

Diseases in the Obstructive Jaundice family:

Jaundice, Familial Obstructive, of Infancy

Diseases related to Obstructive Jaundice via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1069)
# Related Disease Score Top Affiliating Genes
1 cholestasis 32.6 SLC25A13 SLC17A5 GPT GGT1 F2 CCK
2 cholangiocarcinoma 31.4 KRT7 GGT1 CEACAM5 AFP
3 hemochromatosis, neonatal 31.3 SLC25A13 SLC17A5 GGT1
4 acute kidney failure 31.2 GPT F2 ALB
5 pancreatitis 31.1 SERPINA3 GGT1 CRP CCK ALB
6 cholelithiasis 31.1 GPT CRP CCK ALB
7 cholecystitis 31.0 GPT F2 CRP CCK ALB
8 cholangitis 30.9 KRT7 GPT GGT1 F2 CRP CEACAM5
9 bile duct cysts 30.8 KRT7 GPT CEACAM5 ALB AFP
10 hyperthyroidism 30.8 GPT F2 CRP ALB
11 biliary atresia 30.8 KRT7 GPT GGT1 F2 ALB
12 ovarian serous cystadenocarcinoma 30.8 SERPINA3 MUC16 CEACAM5
13 portal hypertension 30.8 SLC17A5 GPT GGT1 F2 ALB AFP
14 bile duct cancer 30.8 KRT7 GPT CEACAM5 ALB AFP
15 cystadenoma 30.7 SERPINA3 MUC16 KRT7 CEACAM5 AFP
16 exanthem 30.7 GPT F2 CRP ALB
17 amyloidosis 30.7 TTR SERPINA3 CRP ALB
18 disseminated intravascular coagulation 30.7 GPT F2 CRP
19 gallbladder cancer 30.7 MUC16 KRT7 GPT CEACAM5 ALB AFP
20 acute cholangitis 30.7 GPT F2 CRP CEACAM5 ALB
21 peritonitis 30.7 MUC16 F2 CRP ALB
22 lymph node tuberculosis 30.6 CRP ALB
23 choledocholithiasis 30.6 SLC17A5 GPT GGT1 F2 CRP CEACAM5
24 appendix adenocarcinoma 30.6 KRT7 CEACAM5
25 fascioliasis 30.6 SLC17A5 GPT GGT1 ALPP ALB
26 acute kidney tubular necrosis 30.5 GPT CRP ALB
27 kidney disease 30.5 TTR LCAT GGT1 F2 CRP ALB
28 suppurative cholangitis 30.5 GPT F2 CRP ALB
29 klatskin's tumor 30.5 KRT7 GPT F2 CEACAM5 ALB AFP
30 aortic aneurysm, familial abdominal, 1 30.5 SERPINA3 MIR122 CRP ALB
31 hepatorenal syndrome 30.5 GPT F2 ALB AFP
32 duodenal obstruction 30.5 GPT CRP CEACAM5 CCK ALB
33 sclerosing cholangitis 30.5 GPT F2 CRP ALB AFP
34 viral infectious disease 30.5 SLC17A5 SERPINA3 MIR122 GPT
35 portal vein thrombosis 30.5 GPT F2 CRP ALB AFP
36 hepatic encephalopathy 30.5 TTR SLC25A13 SLC17A5 GPT F2 ALB
37 miliary tuberculosis 30.5 GPT CRP ALB
38 duodenitis 30.5 CRP CCK ALB
39 ascending cholangitis 30.4 GPT F2 CRP ALB
40 bilirubin metabolic disorder 30.4 SLC25A13 SLC17A5 GPT GGT1 F2 CRP
41 xanthogranulomatous cholecystitis 30.4 SERPINA3 CEACAM5
42 cystadenocarcinoma 30.4 SERPINA3 MUC16 KRT7 CEACAM5 ALPP
43 pancreatic cancer 30.4 SERPINA3 PSG2 MUC16 KRT7 GPT GGT1
44 hypercholesterolemia, familial, 1 30.4 LCAT GPT GHR CRP
45 cavernous hemangioma 30.4 SERPINA3 F2 CEACAM5 ALB AFP
46 intrahepatic cholestasis 30.4 SLC25A13 SLC17A5 GPT GGT1 ALPP ALB
47 viral hepatitis 30.4 SLC17A5 MIR122 GPT GGT1 F2 CRP
48 autoimmune hepatitis 30.4 SLC17A5 GPT GGT1 F2 ALB
49 hydrops of gallbladder 30.3 GPT CRP ALB
50 superior mesenteric artery syndrome 30.3 CRP ALB

Graphical network of the top 20 diseases related to Obstructive Jaundice:

Diseases related to Obstructive Jaundice

Symptoms & Phenotypes for Obstructive Jaundice

UMLS symptoms related to Obstructive Jaundice:

icterus; jaundice (not of newborn)

MGI Mouse Phenotypes related to Obstructive Jaundice:

# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 9.56 ALB CCK GGT1 GHR KRT7 LCAT
2 homeostasis/metabolism MP:0005376 9.53 AFP ALB BLVRB CCK CEACAM5 CRP

Drugs & Therapeutics for Obstructive Jaundice

Drugs for Obstructive Jaundice (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 55)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Lactulose Approved Phase 4 4618-18-2 11333
Nicotinamide Approved, Investigational Phase 3 98-92-0 936
Folic acid Approved, Nutraceutical, Vet_approved Phase 3 59-30-3 6037
Niacin Approved, Investigational, Nutraceutical Phase 3 59-67-6 938
Racemethionine Approved, Experimental, Investigational, Nutraceutical Phase 3 59-51-8, 63-68-3, 348-67-4 6137
6 Vitamins Phase 3
7 Pharmaceutical Solutions Phase 3
8 Folate Phase 3
9 Vitamin B9 Phase 3
10 Vitamin B3 Phase 3
11 Trace Elements Phase 3
12 Nicotinic Acids Phase 3
13 Antimetabolites Phase 3
14 Vasodilator Agents Phase 3
15 Vitamin B Complex Phase 3
16 Hypolipidemic Agents Phase 3
17 Lipid Regulating Agents Phase 3
18 Micronutrients Phase 3
Ursodeoxycholic acid Approved, Investigational Phase 2 128-13-2 31401
Neostigmine Approved, Vet_approved Phase 1, Phase 2 59-99-4 4456 5824
21 Gastrointestinal Agents Phase 2
22 Neurotransmitter Agents Phase 1, Phase 2
23 Anti-Inflammatory Agents Phase 1, Phase 2
24 Cholinesterase Inhibitors Phase 1, Phase 2
25 Cholinergic Agents Phase 1, Phase 2
26 Liver Extracts Phase 1, Phase 2
27 Omega 3 Fatty Acid Phase 1, Phase 2
28 Parenteral Nutrition Solutions Phase 1, Phase 2
bilirubin Phase 1, Phase 2 635-65-4 5280352
30 SMOFlipid Phase 1, Phase 2
31 Fat Emulsions, Intravenous Phase 1, Phase 2
32 Soy Bean Phase 1, Phase 2
33 Olive Phase 1, Phase 2
Norepinephrine Approved Phase 1 51-41-2 439260
Methylene blue Approved, Investigational Phase 1 61-73-4 6099
Prednisone Approved, Vet_approved 53-03-2 5865
Pancrelipase Approved, Investigational 53608-75-6 8519
Trioxsalen Approved 3902-71-4 5585
Ceftriaxone Approved 73384-59-5 5479530
Dihematoporphyrin ether Investigational 97067-70-4
Diethyl ether Experimental 60-29-7 3283
42 Immunoglobulins, Intravenous
43 Immunoglobulins
44 Immunoglobulin G
45 Antibodies
46 Pancreatin
47 Photosensitizing Agents
48 Hematoporphyrins
49 Hematoporphyrin Derivative
50 Dermatologic Agents

Interventional clinical trials:

(show all 45)
# Name Status NCT ID Phase Drugs
1 Phase 4 Study :Human Kidney Histopathology in Acute Obstructive Jaundice: a Prospective Study Completed NCT01090193 Phase 4
2 Re-intervention for Occluded Biliary Metal Stent in Malignant Distal Bile Duct Obstruction: a Prospective Randomized Multi-center Trial Comparing Covered and Uncovered Metal Stent Completed NCT01315522 Phase 4
3 Preoperative Biliary Drainage for the Lower Malignant Obstructive Jaundice: A Phase III, Randomized, Controlled, Single Center Study. Unknown status NCT01744938 Phase 3
4 A Multicenter, Double-Blind, Placebo-Controlled, Randomized Trial of Efficacy and Safety of Remaxol®, a Solution for Intravenous Infusions Produced by STPF "POLYSAN" (Russia), in Patients With Mechanical Jaundice of Non-Malignant Origin Completed NCT03418935 Phase 3 Remaxol (succinate + methionine + inosine + nicotinamide);Ringer's Solution
5 A Multicenter, Double-blind, Placebo-controlled, Randomized Trial of the Efficacy and Safety of Remaxol®, a Solution for Infusions Produced by STPF POLYSAN (Russia), in Patients With Malignant Mechanical Jaundice Completed NCT03416062 Phase 3 Remaxol®;Ringer's Solution
6 Comparison Between Two Methods of Bilateral Stenting for Malignant Hilar Obstruction Withdrawn NCT01622803 Phase 3
7 The Effect of Ursodeoxycholic Acid in Liver Functional Restoration of Patients With Obstructive Jaundice After Endoscopic or Surgical Treatment Unknown status NCT01688375 Phase 2 Ursodeoxycholic Acid
8 A Double Blind, Randomized Controlled Prospective Trial of Endo-biliary Radio-frequency Ablation for Maintenance of Metal Stent Patency in Patients With Malignant Obstructive Jaundice Unknown status NCT01275768 Phase 1, Phase 2
9 The Prevention and Treatment of SIRS in Patients With Cholestatic Jaundice After Operation. Unknown status NCT02279147 Phase 1, Phase 2 neostigmine methylsulfate,raceanisodamine hydrochloride
10 Investigation of the Effect of Intraductal Radiofrequency Ablation in Inoperable Biliopancreatic Tumors Complicated With Obstructive Jaundice Completed NCT02468076 Phase 2
11 Self Expanding Metal Stents (SEMS) or Plastic Stents to Relieve Obstruction of Obstructive Jaundice Prior to Resection of Periampullary Tumors. Completed NCT02166840 Phase 2
12 Compassionate Use of an Intravenous Fat Emulsion Comprised of Soy Oil, Medium Chain Triglycerides, Olive Oil, and Fish Oil for Neonates With Parenteral Nutrition Induced Liver Injury Terminated NCT02721277 Phase 1, Phase 2 SMOFlipid
13 Effect of Methylene Blue on Perioperative Organ Function in Patients With Obstructive Jaundice Unknown status NCT04109859 Phase 1 Saline;Methylene Blue
14 Treatment of Obstructive Jaundice in Autoimmune Pancreatitis and/or Immunoglobulin G4-related Sclerosing Cholangitis by Corticosteroids Unknown status NCT02797665 corticosteroids
15 Process Optimization of Preoperative Biliary Drainage in Patients With Malignant Obstructive Jaundice of Extrahepatic Bile Duct: A Multi-center, Prospective, Open-labeled, Real World Study Based on Electronic Data Capture System Unknown status NCT03527875
16 The Preventive Effects of Pre-treatment With Methylene Blue for Vascular Paralysis of the Patients With Obstructive Jaundice During Operation Unknown status NCT03406676 Methylene Blue
17 Quorum Sensing Signal Molecules (QSSMs) and Immune Dysfunction in Patients Undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP) for Obstructive Jaundice Unknown status NCT01367821
18 A Multisite, Open-label, Prospective Cohort Study Investigating Huaier Granule Combined With Biliary Drainage for Treatment of Malignant Obstructive Jaundice(MOJ) Unknown status NCT03491254
19 The Role of Cholangioscopy and Biliary Radio Frequency Ablation in the Management of Occluded Biliary Self-expanding Metal Stent. Unknown status NCT03133026
20 A Randomized Trial Comparing Covered Metal and Plastic Stents for Preoperative Biliary Decompression in Pancreatic Cancer Unknown status NCT01191814
21 Endoscopic Retrograde Cholangiopancreatography, Endoscopic Ultrasound and Interventional Endoscopy in Pancreatico-biliary, Gastrointestinal and Esophageal Disorders Unknown status NCT01438385
22 Endoscopic Access Loop With Bilio-enteric Anastomosis: A Prospective Randomized Comparison Between Gastric and Subcutaneous Accesses Unknown status NCT03252379
23 Safety and Efficacy of n-3 Fatty Acid-based Parenteral Nutrition in Patients With Obstructive Jaundice: A Propensity-matched Study Completed NCT03376945 trail cohort;control cohort
24 Prospective Study on the Comparison Between the Clinicopathological Outcomes According to the Methods of Preoperative Biliary Drainage in Periampullary Cancers Causing Obstructive Jaundice Completed NCT01134276
25 Endoscopic Ultrasound Evaluation of the Common Bile Duct in Patients With Obstructive Jaundice Due to Bilio-pancreatic Malignancies: a Multicenter Prospective Study (ECCO Trial) Completed NCT05155475
26 Endoscopic Ultrasound Evaluation of the Common Bile Duct in Patients With Obstructive Jaundice Due to Bilio-Pancreatic Malignancies: A Multicenter Prospective Study Completed NCT03494023
27 Endoscopic Versus Percutaneous Biliary Drainage For Hilar Block Due to Carcinoma Gall Bladder: A Randomized Prospective Trial and Quality Of Life Assessment Completed NCT00409864
28 The Status of Advanced Endoscopy in the Era of COVID-19: a Multicenter Study Completed NCT04385147
29 Multicenter Randomized Trial Comparing Covered Metal and Plastic Stents for Preoperative Biliary Decompression in Pancreatic Cancer Completed NCT01675908
30 Endoscopic Versus Percutaneous Biliary Drainage for Resectable Pancreatic Head Cancer With Hyperbilirubinemia and Impact on Pancreaticoduodenectomy: A Prospective Cohort Study Completed NCT04823832
31 Endoscopic Ultrasound-guided Biliary Drainage for Malignant Biliary Obstruction After Failed ERCP: a Single Italian Center Experience Completed NCT03510754
32 A Double-blind, Randomized, Controlled Trial of Air Insufflation Versus Carbon Dioxide Insufflation During Endoscopic Retrograde Cholangiopancreatography (ERCP). Completed NCT01321203
33 Observational Study for Safety and Efficacy of Photodynamic Therapy for Bile Duct Invasion of Hepatocellular Carcinoma Completed NCT01506115 Photofrin
34 Multicenter RCT Comparing Two Brushes of Different Diameters for Biliary Stenosis: RX Cytology Brush, BOSTON vs. Infinity® Brush, US Endoscopy. BIB Study (BIliary Brushing) Completed NCT04251013
35 Full Data BDI Digestif RSCM Completed NCT04582240
36 Biliary Cannulation During Endoscopic Retrograde Cholangiopancreatography: Precut Versus Conventional Cannulation. A Prospective Randomized Study Completed NCT02477228
37 Multicenter Prospective Randomized Controlled Trial of the Nitinol ZILVER Expandable Endoprosthesis in the Palliation of Extrahepatic Malignant Biliary Obstruction Completed NCT00196105
38 The Influence of Antibiotics on the Incidence of Biliary Tract Infections After PTCD for Malignant Obstructive Jaundice Recruiting NCT04620577
39 Role of Ultrasonography as a Single Tool for Guidance of Percutaneous Transhepatic Biliary Drainage in Obstructive Jaundice Recruiting NCT05246176
40 Prospective Evaluation of the Use of a Biodegradable Endoprothesis in the Prevention of Post-Endoscopic Retrograde CholoangioPancreatography Pancreatitis Recruiting NCT03977779
41 Influence of Percutaneous Biliary Drainage on the Change of Enzyme Activity of Matrix Metalloproteinases in the Serum of Patients With Malignant Obstructive Hyperbilirubinemia Recruiting NCT04801914
42 Role of Biodegradable Polydioxanone Biliary Stents for the Percutaneous Treatment of Benign Biliary Strictures. Active, not recruiting NCT05556668
43 Comparison of Efficacy and Safety of Endoscopic Biliary Drainage and Percutaneous Transhepatic Biliary Drainage for the Management of Perihilar Malignant Biliary Obstruction: a Monocentric Retrospective Study Active, not recruiting NCT05078801
44 preGallstep: One-step Laparoscopic Cholecystectomy, Common Bile Duct Exploration and Stone Extraction Versus Two-step Endoscopic Retrograde Cholangiography and Stone Extraction Plus Laparoscopic Cholecystectomy for Common Bile Duct Stones Not yet recruiting NCT04801238
45 Preoperative Endoscopic Biliary Drainage With Self Expanding Metal Stents (SEMS) vs. Direct Surgical Resection for Patients With Severe Obstructive Jaundice Terminated NCT03820544

Search NIH Clinical Center for Obstructive Jaundice

Cochrane evidence based reviews: jaundice, obstructive

Genetic Tests for Obstructive Jaundice

Anatomical Context for Obstructive Jaundice

Organs/tissues related to Obstructive Jaundice:

MalaCards : Liver, Skin, Pancreas, Kidney, Lymph Node, Neutrophil, Lung

Publications for Obstructive Jaundice

Articles related to Obstructive Jaundice:

(show top 50) (show all 8864)
# Title Authors PMID Year
[Analysis of tear enzymes in the diagnosis of obstructive jaundice associated with subhepatic cholestasis]. 53 62
19143075 2008
Improvement in accuracy of gamma-glutamyl transferase for differential diagnosis of biliary atresia by correlation with age. 53 62
18773671 2008
CEA, CA 19-9, and CA 125 in the differential diagnosis of benign and malignant pancreatic diseases with or without jaundice. 53 62
17262731 2007
Autoimmune hepatitis/primary sclerosing cholangitis overlap syndrome in a child: diagnostic usefulness of magnetic resonance cholangiopancreatography. 53 62
15813880 2005
Contrasting liver function test patterns in obstructive jaundice due to biliary strictures [corrected] and stones. 53 62
15625352 2005
A novel inborn error of metabolism detected by elevated methionine and/or galactose in newborn screening: neonatal intrahepatic cholestasis caused by citrin deficiency. 53 62
12692712 2003
[Clinical study on the changes of growth hormone/insulin-like growth factor-I axis in patient with obstructive jaundice]. 53 62
11702667 2001
Infantile cholestatic jaundice associated with adult-onset type II citrullinemia. 53 62
11343052 2001
Factors predicting nutritional derangements in patients with obstructive jaundice: multivariate analysis. 53 62
11344390 2001
Activity of class I and II isoenzymes of alcohol dehydrogenase measured by a fluorometric method in the sera of patients with obstructive jaundice. 53 62
9247733 1997
Clinical values of CA19-9, CA125 and CEA in malignant obstructive jaundice. 53 62
7634181 1995
Discrepancies between lipoprotein(a) concentrations in icteric sera measured by immunonephelometry and electroimmunodiffusion. 53 62
8200119 1994
T-lymphocyte transformation in experimental obstructive jaundice: the role of serum-suppressive factors. 53 62
8109118 1993
Role of endogenous bile on basal and postprandial CCK release in humans. 53 62
8391974 1993
Human lymphocyte responsiveness is not enhanced by relief of biliary obstruction: an in-vitro study. 53 62
2025801 1991
Bile acids in human plasma interfere with cholecystokinin bioassay using dispersed pancreatic acini. 53 62
1995267 1991
Changes in plasma high density lipoprotein cholesterol and phospholipid in acute viral hepatitis and cholestatic jaundice. 53 62
1995758 1991
[Reduction of erythrocyte membrane band 4.2 protein in patients with obstructive jaundice]. 53 62
2255052 1990
A combination of raised serum AST:ALT ratio and erythrocyte mean cell volume level detects excessive alcohol consumption. 53 62
2342668 1990
A case of obstructive jaundice caused by metastasis of breast cancer to the intra/extrahepatic bile duct. 62
35898837 2023
A rare cause of obstructive jaundice in a patient with hepatocellular carcinoma. 62
35999137 2022
A child with pancreatic hemangiomatosis presenting as obstructive jaundice: A rare case report. 62
35753913 2022
Impact of biliary drainage prior to pancreatectomy. 62
33929304 2022
Role of biliary drainage before pancreatoduodenectomy for pancreatic adenocarcinoma: a retrospective study. 62
35230040 2022
Time progression and regional expression of brain oxidative stress induced by obstructive jaundice in rats. 62
36434681 2022
A Rare Cause of Obstructive Jaundice. 62
36372221 2022
Hilar tuberculosis versus Klatskin tumour: a diagnostic challenge. 62
36332934 2022
A rare synchrony of adenocarcinoma of the ampulla with an ileal gastrointestinal stromal tumor: A case report. 62
36438708 2022
Successful Treatment of Pediatric Acute Myeloid Leukemia Presenting with Hyperbilirubinemia Secondary to Myeloid Sarcoma: A Case Report. 62
36360428 2022
Improvement of cholestatic episodes in patients with benign recurrent intrahepatic cholestasis (BRIC) treated with rifampicin. A long-term follow-up. 62
36369734 2022
Conjugated Bile Acids Accelerate Progression of Pancreatic Cancer Metastasis via S1PR2 Signaling in Cholestasis. 62
36396870 2022
Fully covered metal stents vs plastic stents for preoperative biliary drainage in patients with resectable pancreatic cancer without neoadjuvant chemotherapy: A multicenter, prospective, randomized controlled trial. 62
34860467 2022
Vater Papilla-preserving Strategy for Advanced Hepatocellular Carcinoma With Excessive Bile Duct Tumor Thrombus. 62
36288845 2022
Left hepatic lobe agenesis, a rare anatomical condition. 62
35255698 2022
Obstructive jaundice secondary to a pseudoaneurysm in anatomical variant of the hepatic artery. 62
36435377 2022
EUS-guided hepaticogastrostomy in patients with obstructive jaundice after failed or impossible endoscopic retrograde drainage: A multicenter, randomized phase II Study. 62
36204790 2022
An unusual cause of obstructive jaundice in childhood: Intra-choledochal malignant neuroendocrine tumour. 62
35716114 2022
Percutaneous transluminal forceps biopsy with an adjustable curved sheath for obstructive jaundice. 62
35616175 2022
Eosinophilic gastroenteritis: A case series of a rare disease from an apex Tertiary Care Center in South India. 62
36412352 2022
Successful endoscopic treatment of huge infected biloma and hepatic abscess after endoscopic ultrasound-guided hepaticogastrostomy with brain abscess. 62
35763152 2022
Spontaneous retroperitoneal haemorrhage from pancreatoduodenal artery (PDA) rupture and associated complications. 62
36253011 2022
Biliary cystadenoma: Case report with MRI findings and surgical confirmation. 62
35991384 2022
Outcome of primary ERCP versus primary PTC for biliary drainage in malignant hilar biliary strictures: a systematic review and meta-analysis. 62
35941311 2022
Gastrojejunostomy versus endoscopic duodenal stent placement for gastric outlet obstruction in patients with unresectable pancreatic cancer: a propensity score-matched analysis. 62
36258002 2022
Reply to letter to the editor "Re: Identification of Preoperative Risk Factors for Poor Survival in Patients with Resectable Pancreatic Cancer Treated with Upfront Surgery". 62
36315986 2022
Acute Chest Syndrome Masquerading As Sepsis: A Rare Presentation of Sickle Cell Anemia Complication. 62
36381895 2022
The Laparoscopic Cholecystectomy and Common Bile Duct Exploration: A Single-Step Treatment of Pediatric Cholelithiasis and Choledocholithiasis. 62
36291520 2022
Malignant Neuroendocrine Tumor of Gall Bladder: An Incidental Finding. 62
36189571 2022
High rates of recurrence of gallstone associated episodes following acute cholecystitis during long term follow-up: a retrospective comparative study of patients who did not receive surgery. 62
36197463 2022
Pathogenic Novel Heterozygous Variant c.1076c>T p. (Ser359Phe) chr1: 120512166 in NOTCH2 Gene, Type 2 Alagille Syndrome Causing Neonatal Cholestasis: A Case Report. 62
36201396 2022

Variations for Obstructive Jaundice

Expression for Obstructive Jaundice

Search GEO for disease gene expression data for Obstructive Jaundice.

Pathways for Obstructive Jaundice

Pathways related to Obstructive Jaundice according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
Show member pathways
10.56 TTR F2 ALB AFP

GO Terms for Obstructive Jaundice

Cellular components related to Obstructive Jaundice according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 10.2 TTR SERPINA3 PSG2 MUC16 LCAT GHR
2 extracellular exosome GO:0070062 10.02 ALB BLVRB CEACAM5 F2 GGT1 GPT
3 extracellular space GO:0005615 9.68 TTR SERPINA3 MUC16 MIR122 LCAT GPT

Biological processes related to Obstructive Jaundice according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 acute-phase response GO:0006953 9.43 SERPINA3 F2 CRP
2 transport GO:0006810 8.8 SLC25A13 ALB AFP

Sources for Obstructive Jaundice

8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
27 GO
28 GTR
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
36 LifeMap
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
70 Tocris
72 UMLS via Orphanet
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