MCID: OBS082
MIFTS: 52

Obstructive Nephropathy

Categories: Nephrological diseases

Aliases & Classifications for Obstructive Nephropathy

MalaCards integrated aliases for Obstructive Nephropathy:

Name: Obstructive Nephropathy 12 15
Con 12 77
Congenital Obstructive Nephropathy 12
Nephropathy Obstructive 56

Classifications:



External Ids:

Disease Ontology 12 DOID:0070314

Summaries for Obstructive Nephropathy

Disease Ontology : 12 A kidney disease characterized by kidney damage and dysfunction resulting from urinary tract obstruction.

MalaCards based summary : Obstructive Nephropathy, also known as con, is related to renal fibrosis and hydronephrosis. An important gene associated with Obstructive Nephropathy is SKIL (SKI Like Proto-Oncogene), and among its related pathways/superpathways are TGF-Beta Pathway and Endometrial cancer. The drugs Etomidate and Sevoflurane have been mentioned in the context of this disorder. Affiliated tissues include kidney, t cells and liver, and related phenotypes are cardiovascular system and growth/size/body region

Wikipedia : 77 The Crawford expedition was a campaign on the western front of the American Revolutionary War, and one... more...

Related Diseases for Obstructive Nephropathy

Diseases related to Obstructive Nephropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 395)
# Related Disease Score Top Affiliating Genes
1 renal fibrosis 30.5 HGF REN SMAD2 SMAD3 TGFB1
2 hydronephrosis 30.0 ALB EGF TGFB1
3 kidney disease 29.8 ACE AGT AGTR2 ALB REN TGFB1
4 aortic valve disease 1 29.6 ACE REN TGFB1
5 heart valve disease 29.5 ACE REN TGFB1
6 liver cirrhosis 29.5 ALB HGF REN TGFB1
7 iga glomerulonephritis 29.4 ACE ALB REN TGFB1
8 arteries, anomalies of 29.4 ACE AGT ALB REN
9 microvascular complications of diabetes 3 29.3 ACE AGT ALB
10 end stage renal failure 29.1 ACE AGT ALB TGFB1
11 pulmonary fibrosis, idiopathic 29.1 AGT HGF SMAD2 SMAD3 TGFB1
12 myocardial infarction 29.0 ACE AGT AGTR2 ALB REN
13 chronic ulcer of skin 28.9 ALB EGF
14 large intestine cancer 28.9 ALB EGF HGF SMAD2
15 chronic kidney failure 28.8 ACE AGT ALB REN TGFB1
16 hypertension, essential 28.6 ACE AGT AGTR2 ALB REN
17 autosomal dominant polycystic kidney disease 28.4 ACE AGT ALB EGF REN
18 breast reconstruction 11.2
19 degos 'en cocarde' erythrokeratoderma 10.6
20 xp22.3 microdeletion syndrome 10.4
21 pelger-huet anomaly 10.4
22 hepatitis 10.3
23 multicystic dysplastic kidney 10.3 AGTR2 REN
24 hypoaldosteronism 10.2 ACE REN
25 malignant secondary hypertension 10.2 AGTR2 REN
26 renal artery obstruction 10.2 ACE REN
27 loeffler syndrome 10.2 ACE ALB
28 familial vesicoureteral reflux 10.2 ACE AGTR2 TGFB1
29 benign essential hypertension 10.2 ALB REN
30 hypertrophic scars 10.2 SMAD2 SMAD3 TGFB1
31 keloids 10.2 SMAD2 SMAD3 TGFB1
32 asthma 10.2
33 nephrogenic systemic fibrosis 10.2 SMAD2 SMAD3 TGFB1
34 kidney papillary necrosis 10.1 ALB REN
35 hypertension, diastolic 10.1 ACE REN
36 hypertensive encephalopathy 10.1 ACE REN
37 malignant essential hypertension 10.1 ACE AGTR2 REN
38 tricuspid valve prolapse 10.1 EGF SMAD3
39 biliary atresia 10.1 ALB HGF TGFB1
40 hypertensive retinopathy 10.1 ACE REN
41 atrial fibrillation 10.1
42 acute kidney tubular necrosis 10.1 ALB HAVCR1 HGF
43 pseudohyperkalemia, familial, 2, due to red cell leak 10.1 ACE AGTR2 REN
44 lung cancer 10.1
45 burns 10.1 ALB HGF
46 congenital anomalies of kidney and urinary tract 2 10.1 EGF HAVCR1 TGFB1
47 pediatric hypertension 10.1 ACE AGT
48 obstructive jaundice 10.1 ALB HGF REN
49 prostate cancer 10.1
50 prostate cancer, hereditary, 8 10.1

Graphical network of the top 20 diseases related to Obstructive Nephropathy:



Diseases related to Obstructive Nephropathy

Symptoms & Phenotypes for Obstructive Nephropathy

MGI Mouse Phenotypes related to Obstructive Nephropathy:

47 (show all 11)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.15 ACE AGT AGTR2 CLU HGF REN
2 growth/size/body region MP:0005378 10.13 ACE AGT AGTR2 EGF HGF REN
3 homeostasis/metabolism MP:0005376 10.1 ACE AGT AGTR2 ALB CLU REN
4 endocrine/exocrine gland MP:0005379 10.06 ACE AGTR2 ALB EGF SKIL SMAD2
5 immune system MP:0005387 10.02 ACE AGT CLU EGF REN SKIL
6 mortality/aging MP:0010768 9.96 ACE AGT AGTR2 ALB HGF REN
7 digestive/alimentary MP:0005381 9.95 AGTR2 ALB EGF SMAD2 SMAD3 TGFB1
8 liver/biliary system MP:0005370 9.87 ACE AGT ALB HGF SMAD2 SMAD3
9 neoplasm MP:0002006 9.7 ACE AGTR2 ALB SKIL SMAD2 SMAD3
10 renal/urinary system MP:0005367 9.56 ACE AGT AGTR2 ALB CLU REN
11 reproductive system MP:0005389 9.23 ACE AGT EGF REN SKIL SMAD2

Drugs & Therapeutics for Obstructive Nephropathy

Drugs for Obstructive Nephropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 25)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Etomidate Approved Not Applicable 33125-97-2 667484 36339
2
Sevoflurane Approved, Vet_approved Not Applicable 28523-86-6 5206
3
Sufentanil Approved, Investigational Not Applicable 56030-54-7 41693
4
Propofol Approved, Investigational, Vet_approved Not Applicable 2078-54-8 4943
5
Midazolam Approved, Illicit Not Applicable 59467-70-8 4192
6
Cisatracurium Approved Not Applicable 96946-41-7
7
Remifentanil Approved Not Applicable 132875-61-7 60815
8 Anesthetics Not Applicable
9 Anesthetics, General Not Applicable
10 Anti-Anxiety Agents Not Applicable
11 Analgesics, Opioid Not Applicable
12 Central Nervous System Depressants Not Applicable
13 Tranquilizing Agents Not Applicable
14 Hypnotics and Sedatives Not Applicable
15 GABA Agents Not Applicable
16 Neurotransmitter Agents Not Applicable
17 Neuromuscular Blocking Agents Not Applicable
18 GABA Modulators Not Applicable
19 Anesthetics, Intravenous Not Applicable
20 Peripheral Nervous System Agents Not Applicable
21 Neuromuscular Agents Not Applicable
22 Adjuvants, Anesthesia Not Applicable
23 Psychotropic Drugs Not Applicable
24 Narcotics Not Applicable
25 Analgesics Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Hemodynamics and Vital Organ Function in Intracerebral Hemorrhage Unknown status NCT03129009 Not Applicable Total intravenous anesthesia group;Balanced anesthesia group
2 Renal Resistive Index as a Marker of Severity and Treatment Outcomes in Lupus Nephritis Not yet recruiting NCT03958851

Search NIH Clinical Center for Obstructive Nephropathy

Genetic Tests for Obstructive Nephropathy

Anatomical Context for Obstructive Nephropathy

MalaCards organs/tissues related to Obstructive Nephropathy:

42
Kidney, T Cells, Liver, Heart, Prostate, Testes, Brain

Publications for Obstructive Nephropathy

Articles related to Obstructive Nephropathy:

(show top 50) (show all 2286)
# Title Authors Year
1
Atrial Fibrillation Ablation Should Be First-Line Therapy in Heart Failure Patients: CON. ( 30926021 )
2019
2
Con: Tolvaptan for autosomal dominant polycystic kidney disease-do we know all the answers? ( 30312449 )
2019
3
Con: Liver Biopsy Remains the Gold Standard to Evaluate Fibrosis in Patients With Nonalcoholic Fatty Liver Disease. ( 31061705 )
2019
4
Pro-Con Debate: Component resolved diagnostic testing is not useful for making food allergy diagnoses. ( 30772391 )
2019
5
CD8+ T cell/IL-33/ILC2 axis exacerbates the liver injury in Con A-induced hepatitis in T cell-transferred Rag2-deficient mice. ( 30430216 )
2019
6
Tamoxifen ameliorates obstructive nephropathy through Src and the PI3K/Akt/mTOR pathway. ( 30304547 )
2019
7
Obstructive nephropathy: simple yet complicated! ( 30386975 )
2019
8
Protease-activated receptor-1 contributes to renal injury and interstitial fibrosis during chronic obstructive nephropathy. ( 30485646 )
2019
9
A Novel Biomarker for Acute Kidney Injury, Vanin-1, for Obstructive Nephropathy: A Prospective Cohort Pilot Study. ( 30791405 )
2019
10
Full age spectrum equation versus CKD-EPI and MDRD equations to estimate glomerular filtration rate in adults with obstructive nephropathy. ( 30991866 )
2019
11
O bladder, where art thou? An unusual cause of obstructive nephropathy. ( 31085624 )
2019
12
Shenkang injection, a modern preparation of Chinese patent medicine, diminishes tubulointerstitial fibrosis in obstructive nephropathy via targeting pericyte-myofibroblast transition. ( 31105812 )
2019
13
Oligometastatic Prostate Cancer Should Be Studied and Treated Differently to High-volume Disease. Con: The Underlying Biology is the Same, So They Should Not Be Treated Differently. ( 30803925 )
2019
14
Plasma metabolites predict both insulin resistance and incident type 2 diabetes: a metabolomics approach within the Prevención con Dieta Mediterránea (PREDIMED) study. ( 30796776 )
2019
15
Con: vascular access surveillance in mature fistulas: is it worthwhile? ( 30768169 )
2019
16
Are Slings Still the Gold Standard for Female Stress Urinary Incontinence? Con: Artificial Urinary Sphincter for Female Incontinence. ( 30772361 )
2019
17
Con: OIT is safe/better than food avoidance. ( 30772390 )
2019
18
Effect of early experience on neuronal and behavioral responses to con- and heterospecific odors in closely related Mus taxa: epigenetic contribution in formation of precopulatory isolation. ( 30813903 )
2019
19
Opioid-free anaesthesia: Con: it is too early to adopt opioid-free anaesthesia today. ( 30817360 )
2019
20
Importance of diastolic pressure in septic shock: Con - Response. ( 30826175 )
2019
21
Con: should asymptomatic patients with moderate-to-severe 
OSA be treated? ( 30838055 )
2019
22
Del Nido Cardioplegia Should Be Used in All Adults Undergoing Cardiac Surgery: Con. ( 30852089 )
2019
23
CON: Levosimendan should be used in clinical practice for patients with significantly impaired left ventricular function undergoing cardiac surgery. ( 30857925 )
2019
24
Con: Hyperoxia Should Not Be Used Routinely in the Management of Cardiopulmonary Bypass. ( 30890393 )
2019
25
Características otorrinolaringológicas en niños con trisomía 21: un estudio de 171 pacientes en el Hospital Infantil de México Federico Gómez. ( 30907388 )
2019
26
Factores asociados con la picadura de alacrán en escolares: estudio transversal en dos comunidades rurales de Guerrero, México. ( 30907390 )
2019
27
Metabolomics profiling in a mouse model reveals protective effect of Sancao granule on Con A-Induced liver injury. ( 30930257 )
2019
28
Densidad mineral ósea e indicadores bioquímicos y hormonales en niños con parálisis cerebral cuadripléjica. ( 30958686 )
2019
29
The Opioid Wars-CON: The Risks of Opioids for Pain Management Outweigh the Benefits. ( 30985394 )
2019
30
Con: The Abstinence Period Should Be Determined on a Case-by-Case Basis. ( 30988944 )
2019
31
Impact of iodine concentration and iodine delivery rate on contrast enhancement in coronary CT angiography: a randomized multicenter trial (CT-CON). ( 31016447 )
2019
32
La protección al consumidor en las webs de juego online de los operadores con licencia en España. ( 31018003 )
2019
33
Validación de Belief Medicines Questionnaire y Self-efficacy for Appropriate Medication Use Scale para medir adherencia al tratamiento farmacológico en pacientes con enfermedad inflamatoria intestinal. ( 31056588 )
2019
34
Síntesis y uso de histidinato de cobre en niños con enfermedad de Menkes en México. ( 31056589 )
2019
35
Enfermedad periodontal como factor de riesgo adicional asociado con nacimiento pretérmino en México: un estudio de casos y controles. ( 31056598 )
2019
36
Inercia clínica en el tratamiento con insulina en el primer nivel de atención. ( 31056606 )
2019
37
Factores predictores del estado libre de cálculos en la primera ureteroscopia flexible con litotricia láser. ( 31056613 )
2019
38
Discurso del académico doctor Guillermo Fajardo Ortiz con motivo de la adición de su nombre al del Hospital General Regional 2 del Instituto Mexicano del Seguro Social. ( 31056614 )
2019
39
Encuesta en población abierta respecto a términos relacionados con decisiones al final de la vida. ( 31056615 )
2019
40
Con-Strain Imaging Should Not Be a Routine Part of the Intraoperative TEE Exam During Cardiac Surgery. ( 31060945 )
2019
41
Assessment of Alimentación Normal con Ajuste de Insulina (ANAIS), a Spanish version of the DAFNE programme, in people with Type 1 diabetes: a randomized controlled parallel trial. ( 31087451 )
2019
42
Valve-sparing aortic root surgery. CON: remodeling. ( 28918516 )
2019
43
PRO-CON debate: valve sparing aortic root surgery. PRO: reimplantation. ( 29019069 )
2019
44
Conflicts and con-fusions confounding compassion in acute care: Creating dialogical moral space. ( 29281923 )
2019
45
Too much nephrology? The CKD epidemic is real and concerning. A CON view. ( 30418616 )
2019
46
Con: The Unclear Benefit of Albumin. ( 30447173 )
2019
47
ApoB in clinical care: Pro and Con. ( 30463677 )
2019
48
Con: Modified Ultrafiltration in Pediatric Cardiac Surgery Is No Longer Necessary. ( 30587424 )
2019
49
Glycosylated naphthalimides and naphthalimide Tröger's bases as fluorescent aggregation probes for Con A. ( 30629076 )
2019
50
Correction: Glycosylated naphthalimides and naphthalimide Tröger's bases as fluorescent aggregation probes for Con A. ( 30702731 )
2019

Variations for Obstructive Nephropathy

Expression for Obstructive Nephropathy

Search GEO for disease gene expression data for Obstructive Nephropathy.

Pathways for Obstructive Nephropathy

Pathways related to Obstructive Nephropathy according to GeneCards Suite gene sharing:

(show all 42)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.32 AGT AGTR2 EGF HGF PDGFD SKIL
2
Show member pathways
12.77 EGF PDGFD SMAD2 SMAD3 TGFB1
3
Show member pathways
12.74 ACE AGT AGTR2 EGF HGF PDGFD
4 12.73 EGF HGF SMAD2 SMAD3 TGFB1
5
Show member pathways
12.66 EGF HGF SMAD2 SMAD3 TGFB1
6
Show member pathways
12.61 EGF HGF PDGFD TGFB1
7
Show member pathways
12.45 EGF SMAD2 SMAD3 TGFB1
8
Show member pathways
12.38 PDGFD SMAD2 SMAD3 TGFB1
9
Show member pathways
12.19 SKIL SMAD2 SMAD3 TGFB1
10 12.14 SKIL SMAD2 SMAD3 TGFB1
11 12.05 SMAD2 SMAD3 TGFB1
12 12.05 EGF SMAD2 SMAD3 TGFB1
13
Show member pathways
12.02 EGF SMAD3 TGFB1
14 12 SKIL SMAD2 SMAD3
15 11.97 AGT SMAD3 TGFB1
16
Show member pathways
11.96 SMAD2 SMAD3 TGFB1
17
Show member pathways
11.96 EGF SMAD2 SMAD3 TGFB1
18 11.94 SKIL SMAD2 SMAD3 TGFB1
19 11.94 ALB EGF HGF TGFB1
20 11.92 SKIL SMAD2 SMAD3 TGFB1
21 11.83 SMAD2 SMAD3 TGFB1
22 11.81 SMAD2 SMAD3 TGFB1
23
Show member pathways
11.79 SMAD2 SMAD3 TGFB1
24 11.78 SMAD2 SMAD3 TGFB1
25 11.77 HGF REN TGFB1
26 11.69 SKIL SMAD2 SMAD3
27 11.65 EGF HGF PDGFD TGFB1
28
Show member pathways
11.64 SMAD2 SMAD3 TGFB1
29 11.61 ACE AGT REN
30 11.6 EGF SMAD3 TGFB1
31 11.58 SKIL SMAD2 SMAD3 TGFB1
32 11.56 SKIL SMAD2 SMAD3 TGFB1
33
Show member pathways
11.51 EGF HGF PDGFD SKIL SMAD2 SMAD3
34
Show member pathways
11.47 EGF SMAD2 SMAD3 TGFB1
35 11.47 EGF HGF SKIL TGFB1
36 11.42 EGF HGF TGFB1
37 11.33 SKIL SMAD2 SMAD3 TGFB1
38 10.95 SMAD2 SMAD3
39 10.93 HGF SMAD2 SMAD3 TGFB1
40 10.9 HGF TGFB1
41 10.89 SMAD2 SMAD3 TGFB1
42 10.78 EGF SKIL SMAD2 SMAD3 TGFB1

GO Terms for Obstructive Nephropathy

Cellular components related to Obstructive Nephropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.85 ACE AGT ALB CLU EGF HGF
2 protein-containing complex GO:0032991 9.8 ALB CLU SKIL SMAD2 SMAD3
3 extracellular region GO:0005576 9.65 ACE AGT ALB CLU EGF HGF
4 blood microparticle GO:0072562 9.62 AGT ALB CLU TGFB1
5 SMAD protein complex GO:0071141 9.37 SMAD2 SMAD3
6 heteromeric SMAD protein complex GO:0071144 9.26 SMAD2 SMAD3
7 platelet alpha granule lumen GO:0031093 9.02 ALB CLU EGF HGF TGFB1

Biological processes related to Obstructive Nephropathy according to GeneCards Suite gene sharing:

(show top 50) (show all 69)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.91 AGT CLU TGFB1
2 cell cycle arrest GO:0007050 9.91 SKIL SMAD3 TGFB1
3 kidney development GO:0001822 9.88 ACE AGT REN
4 negative regulation of cell growth GO:0030308 9.88 AGT AGTR2 SMAD3 TGFB1
5 wound healing GO:0042060 9.87 SMAD2 SMAD3 TGFB1
6 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.85 AGT HGF PDGFD
7 positive regulation of MAP kinase activity GO:0043406 9.85 EGF PDGFD TGFB1
8 positive regulation of cell migration GO:0030335 9.85 EGF HGF PDGFD SMAD3 TGFB1
9 cellular response to transforming growth factor beta stimulus GO:0071560 9.84 PDGFD SMAD3 TGFB1
10 SMAD protein signal transduction GO:0060395 9.83 SMAD2 SMAD3 TGFB1
11 transforming growth factor beta receptor signaling pathway GO:0007179 9.83 SKIL SMAD2 SMAD3 TGFB1
12 positive regulation of fibroblast proliferation GO:0048146 9.82 AGT PDGFD TGFB1
13 positive regulation of epithelial to mesenchymal transition GO:0010718 9.8 SMAD2 SMAD3 TGFB1
14 ureteric bud development GO:0001657 9.8 SMAD2 SMAD3 TGFB1
15 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.8 AGT EGF HGF TGFB1
16 positive regulation of protein tyrosine kinase activity GO:0061098 9.79 ACE AGT EGF
17 blood vessel remodeling GO:0001974 9.77 ACE AGT AGTR2
18 endoderm development GO:0007492 9.77 SMAD2 SMAD3 TGFB1
19 cell-cell junction organization GO:0045216 9.74 SMAD3 TGFB1
20 positive regulation of blood vessel diameter GO:0097755 9.74 AGT AGTR2
21 regulation of vasoconstriction GO:0019229 9.74 ACE AGT
22 adrenal gland development GO:0030325 9.74 SMAD2 SMAD3
23 positive regulation of blood pressure GO:0045777 9.73 ACE AGT
24 embryonic pattern specification GO:0009880 9.73 SMAD2 SMAD3
25 signal transduction involved in regulation of gene expression GO:0023019 9.73 SMAD2 SMAD3
26 vasodilation GO:0042311 9.73 AGT AGTR2
27 negative regulation of release of cytochrome c from mitochondria GO:0090201 9.73 CLU HGF
28 negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 9.73 SKIL SMAD2 SMAD3 TGFB1
29 nitric oxide mediated signal transduction GO:0007263 9.72 AGT AGTR2
30 regulation of peptidyl-tyrosine phosphorylation GO:0050730 9.72 EGF PDGFD
31 activin receptor signaling pathway GO:0032924 9.72 SMAD2 SMAD3
32 cellular sodium ion homeostasis GO:0006883 9.72 AGT AGTR2
33 positive regulation of cellular protein metabolic process GO:0032270 9.72 AGT TGFB1
34 cell growth involved in cardiac muscle cell development GO:0061049 9.71 AGT AGTR2
35 positive regulation of superoxide anion generation GO:0032930 9.71 AGT TGFB1
36 positive regulation of ubiquitin-dependent protein catabolic process GO:2000060 9.71 CLU EGF
37 amyloid-beta metabolic process GO:0050435 9.71 ACE REN
38 positive regulation of renal sodium excretion GO:0035815 9.7 AGT AGTR2
39 regulation of blood vessel diameter GO:0097746 9.7 ACE AGTR2
40 angiotensin maturation GO:0002003 9.7 ACE REN
41 nodal signaling pathway GO:0038092 9.69 SMAD2 SMAD3
42 primary miRNA processing GO:0031053 9.69 SMAD2 SMAD3
43 response to cholesterol GO:0070723 9.69 SMAD2 TGFB1
44 regulation of transforming growth factor beta receptor signaling pathway GO:0017015 9.69 SMAD2 SMAD3 TGFB1
45 embryonic foregut morphogenesis GO:0048617 9.68 SMAD2 SMAD3
46 pericardium development GO:0060039 9.68 SMAD2 SMAD3
47 regulation of protein import into nucleus GO:0042306 9.68 AGTR2 TGFB1
48 regulation of blood pressure GO:0008217 9.67 ACE AGT AGTR2 REN
49 common-partner SMAD protein phosphorylation GO:0007182 9.66 SMAD2 TGFB1
50 regulation of systemic arterial blood pressure by renin-angiotensin GO:0003081 9.66 ACE AGT

Molecular functions related to Obstructive Nephropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 R-SMAD binding GO:0070412 9.48 SMAD2 SMAD3
2 tau protein binding GO:0048156 9.46 CLU SMAD2
3 enhancer binding GO:0035326 9.43 SMAD2 SMAD3
4 SMAD binding GO:0046332 9.43 SKIL SMAD2 SMAD3
5 co-SMAD binding GO:0070410 9.4 SMAD2 SMAD3
6 type I transforming growth factor beta receptor binding GO:0034713 9.37 SMAD2 TGFB1
7 primary miRNA binding GO:0070878 9.32 SMAD2 SMAD3
8 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity GO:0030618 9.16 SMAD2 SMAD3
9 transforming growth factor beta receptor binding GO:0005160 9.13 SMAD2 SMAD3 TGFB1
10 growth factor activity GO:0008083 9.02 AGT EGF HGF PDGFD TGFB1

Sources for Obstructive Nephropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....