MCID: OCC003
MIFTS: 23

Occipital Lobe Neoplasm

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Occipital Lobe Neoplasm

MalaCards integrated aliases for Occipital Lobe Neoplasm:

Name: Occipital Lobe Neoplasm 12 15
Neoplasm of Occipital Lobe 12 70
Malignant Neoplasm of Occipital Lobe 12
Tumor of Occipital Lobe 12

Classifications:



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Disease Ontology 12 DOID:910
ICD9CM 34 191.4
NCIt 50 C5574
SNOMED-CT 67 126957005 93928006
ICD10 32 C71.4
UMLS 70 C0153638 C1263889

Summaries for Occipital Lobe Neoplasm

MalaCards based summary : Occipital Lobe Neoplasm, also known as neoplasm of occipital lobe, is related to adenosquamous lung carcinoma and pulmonary large cell neuroendocrine carcinoma. An important gene associated with Occipital Lobe Neoplasm is TPR (Translocated Promoter Region, Nuclear Basket Protein), and among its related pathways/superpathways are Pathways in cancer and Glioma. Affiliated tissues include occipital lobe, brain and eye, and related phenotype is Decreased viability after Chlamydia trachomatis serovar L2 infection and TNF-alpha/CHX stimulation.

Related Diseases for Occipital Lobe Neoplasm

Graphical network of the top 20 diseases related to Occipital Lobe Neoplasm:



Diseases related to Occipital Lobe Neoplasm

Symptoms & Phenotypes for Occipital Lobe Neoplasm

GenomeRNAi Phenotypes related to Occipital Lobe Neoplasm according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability after Chlamydia trachomatis serovar L2 infection and TNF-alpha/CHX stimulation GR00206-A 8.62 KIF5B MET

Drugs & Therapeutics for Occipital Lobe Neoplasm

Search Clinical Trials , NIH Clinical Center for Occipital Lobe Neoplasm

Genetic Tests for Occipital Lobe Neoplasm

Anatomical Context for Occipital Lobe Neoplasm

MalaCards organs/tissues related to Occipital Lobe Neoplasm:

40
Occipital Lobe, Brain, Eye

Publications for Occipital Lobe Neoplasm

Articles related to Occipital Lobe Neoplasm:

# Title Authors PMID Year
1
Ocular motility testing in the evaluation of visual hallucinations. 61
6859186 1983

Variations for Occipital Lobe Neoplasm

Expression for Occipital Lobe Neoplasm

Search GEO for disease gene expression data for Occipital Lobe Neoplasm.

Pathways for Occipital Lobe Neoplasm

Pathways related to Occipital Lobe Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 12.08 TPR TFG MET EML4 ALK
2
Show member pathways
12.06 MET KIF5B EML4 ALK
3 11.67 ROS1 MET ALK
4 10.5 ROS1 MET EML4 ALK
5 10.3 KLC1 KIF5B

GO Terms for Occipital Lobe Neoplasm

Cellular components related to Occipital Lobe Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 microtubule GO:0005874 9.43 KLC1 KIF5B EML4
2 cytoskeleton GO:0005856 9.35 TPR SPTBN1 KLC1 KIF5B EML4
3 kinesin complex GO:0005871 9.16 KLC1 KIF5B
4 receptor complex GO:0043235 8.8 ROS1 MET ALK

Biological processes related to Occipital Lobe Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidyl-tyrosine phosphorylation GO:0018108 9.43 ROS1 MET ALK
2 hippocampus development GO:0021766 9.4 KIF5B ALK
3 positive regulation of protein localization to plasma membrane GO:1903078 9.37 SPTBN1 KIF5B
4 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.33 ROS1 MET ALK
5 positive regulation of intracellular protein transport GO:0090316 9.32 TPR KIF5B
6 positive regulation of kinase activity GO:0033674 9.13 ROS1 MET ALK
7 stress granule disassembly GO:0035617 8.62 KLC1 KIF5B

Molecular functions related to Occipital Lobe Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein tyrosine kinase activity GO:0004713 9.13 ROS1 MET ALK
2 transmembrane receptor protein tyrosine kinase activity GO:0004714 8.8 ROS1 MET ALK

Sources for Occipital Lobe Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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