MCID: OCC004
MIFTS: 21

Occlusion of Gallbladder

Categories: Gastrointestinal diseases

Aliases & Classifications for Occlusion of Gallbladder

MalaCards integrated aliases for Occlusion of Gallbladder:

Name: Occlusion of Gallbladder 12 15
Obstruction of Gallbladder 12 32

Classifications:



External Ids:

Disease Ontology 12 DOID:9714
ICD9CM 34 575.2
NCIt 50 C78308
SNOMED-CT 67 197415009
ICD10 32 K82.0
UMLS 70 C0156214

Summaries for Occlusion of Gallbladder

MalaCards based summary : Occlusion of Gallbladder, also known as obstruction of gallbladder, is related to congenital dyserythropoietic anemia and hereditary spherocytosis. An important gene associated with Occlusion of Gallbladder is CTSB (Cathepsin B), and among its related pathways/superpathways are Cell surface interactions at the vascular wall and Hematopoietic cell lineage. Affiliated tissues include pancreas and brain, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Occlusion of Gallbladder

Diseases related to Occlusion of Gallbladder via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 congenital dyserythropoietic anemia 9.7 TFRC CD44
2 hereditary spherocytosis 9.6 TFRC CD44
3 brain cancer 9.5 TFRC CD44
4 rheumatoid arthritis 9.4 TFRC CTSB CD44

Symptoms & Phenotypes for Occlusion of Gallbladder

GenomeRNAi Phenotypes related to Occlusion of Gallbladder according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-104 8.92 CTSB
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-14 8.92 TFRC
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-142 8.92 TFRC
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-167 8.92 TFRC

MGI Mouse Phenotypes related to Occlusion of Gallbladder:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.56 CD44 CTSB SLC7A11 TFRC
2 immune system MP:0005387 9.46 CD44 CTSB SLC7A11 TFRC
3 integument MP:0010771 9.26 CD44 CTSB SLC7A11 TFRC
4 neoplasm MP:0002006 8.8 CD44 CTSB SLC7A11

Drugs & Therapeutics for Occlusion of Gallbladder

Search Clinical Trials , NIH Clinical Center for Occlusion of Gallbladder

Genetic Tests for Occlusion of Gallbladder

Anatomical Context for Occlusion of Gallbladder

MalaCards organs/tissues related to Occlusion of Gallbladder:

40
Pancreas, Brain

Publications for Occlusion of Gallbladder

Articles related to Occlusion of Gallbladder:

# Title Authors PMID Year
1
[Mitochondrial and lysosomal pathways of death of hepatocytes of lamprey Lampetra fluviatilis L]. 61
23401965 2012
2
[Rapid diagnosis of purulent-destructive forms of acute calculous cholecystitis]. 61
16007022 2005
3
Gallbladder wall thickening secondary to focal lymphatic obstruction. 61
6842662 1983
4
Spectrum of 99m-Tc-IDA cholescintigraphic patterns in acute cholecystitis. 61
7192874 1981

Variations for Occlusion of Gallbladder

Expression for Occlusion of Gallbladder

Search GEO for disease gene expression data for Occlusion of Gallbladder.

Pathways for Occlusion of Gallbladder

Pathways related to Occlusion of Gallbladder according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.41 SLC7A11 CD44
2 10.95 TFRC CD44
3 10.24 TFRC SLC7A11

GO Terms for Occlusion of Gallbladder

Cellular components related to Occlusion of Gallbladder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 basolateral plasma membrane GO:0016323 9.16 TFRC CD44
2 melanosome GO:0042470 8.96 TFRC CTSB
3 cell surface GO:0009986 8.8 TFRC SLC7A11 CD44

Biological processes related to Occlusion of Gallbladder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of cell proliferation GO:0042127 9.26 TFRC SLC7A11
2 leukocyte migration GO:0050900 9.16 SLC7A11 CD44
3 viral entry into host cell GO:0046718 8.96 TFRC CTSB
4 positive regulation of peptidyl-serine phosphorylation GO:0033138 8.62 TFRC CD44

Molecular functions related to Occlusion of Gallbladder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 collagen binding GO:0005518 8.62 CTSB CD44

Sources for Occlusion of Gallbladder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....