MCID: OCC005
MIFTS: 26

Occlusion Precerebral Artery

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Occlusion Precerebral Artery

MalaCards integrated aliases for Occlusion Precerebral Artery:

Name: Occlusion Precerebral Artery 12 15
Occlusion and Stenosis of Multiple and Bilateral Precerebral Arteries 12
Occlusion and Stenosis of Precerebral Artery 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5976
ICD10 33 I65.9 I65.3
ICD9CM 35 433 433.3 433.9

Summaries for Occlusion Precerebral Artery

MalaCards based summary : Occlusion Precerebral Artery, also known as occlusion and stenosis of multiple and bilateral precerebral arteries, is related to basilar artery occlusion and carotid artery occlusion. An important gene associated with Occlusion Precerebral Artery is BCO1 (Beta-Carotene Oxygenase 1), and among its related pathways/superpathways are Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways and Formation of Fibrin Clot (Clotting Cascade). Related phenotypes are growth/size/body region and homeostasis/metabolism

Related Diseases for Occlusion Precerebral Artery

Graphical network of the top 20 diseases related to Occlusion Precerebral Artery:



Diseases related to Occlusion Precerebral Artery

Symptoms & Phenotypes for Occlusion Precerebral Artery

MGI Mouse Phenotypes related to Occlusion Precerebral Artery:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 9.81 PLG BCO1 CA4 CASP3 GRIN1 INO80
2 homeostasis/metabolism MP:0005376 9.61 PLAT PLG BCO1 CA4 CASP3 GRIN1
3 reproductive system MP:0005389 9.23 PLG CA4 CASP3 GRIN1 INO80 MAP2

Drugs & Therapeutics for Occlusion Precerebral Artery

Search Clinical Trials , NIH Clinical Center for Occlusion Precerebral Artery

Genetic Tests for Occlusion Precerebral Artery

Anatomical Context for Occlusion Precerebral Artery

Publications for Occlusion Precerebral Artery

Variations for Occlusion Precerebral Artery

Expression for Occlusion Precerebral Artery

Search GEO for disease gene expression data for Occlusion Precerebral Artery.

Pathways for Occlusion Precerebral Artery

GO Terms for Occlusion Precerebral Artery

Cellular components related to Occlusion Precerebral Artery according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 8.92 CA4 GRIN1 PLAT PLG

Biological processes related to Occlusion Precerebral Artery according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.5 KLKB1 PLAT PLG
2 bicarbonate transport GO:0015701 9.43 CA1 CA4
3 cellular response to organic substance GO:0071310 9.4 CASP3 MAP2
4 one-carbon metabolic process GO:0006730 9.37 CA1 CA4
5 regulation of axonogenesis GO:0050770 9.26 GRIN1 MAP2
6 plasminogen activation GO:0031639 9.16 KLKB1 PLAT
7 positive regulation of fibrinolysis GO:0051919 8.96 KLKB1 PLG
8 fibrinolysis GO:0042730 8.8 KLKB1 PLAT PLG

Molecular functions related to Occlusion Precerebral Artery according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidase activity GO:0008233 9.56 CASP3 KLKB1 PLAT PLG
2 serine-type endopeptidase activity GO:0004252 9.54 KLKB1 PLAT PLG
3 calmodulin binding GO:0005516 9.5 GRIN1 MAP2 MBP
4 serine-type peptidase activity GO:0008236 9.33 KLKB1 PLAT PLG
5 signaling receptor binding GO:0005102 9.26 GRIN1 HSPA1A PLAT PLG
6 carbonate dehydratase activity GO:0004089 8.62 CA1 CA4

Sources for Occlusion Precerebral Artery

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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