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MCID: OCC001
MIFTS: 30

Occupational Dermatitis

Categories: Immune diseases, Skin diseases
Genes Tissues Related diseases Publications Drugs
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Aliases & Classifications for Occupational Dermatitis

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MalaCards integrated aliases for Occupational Dermatitis:

Name: Occupational Dermatitis 12 15 17
Dermatitis, Occupational 44 72
Occupational Allergic Contact Dermatitis 12
Occupational Eczema 12

Classifications:

MalaCards categories:
Anatomical: Skin diseases Immune diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:4404
MeSH 44 D009783
NCIt 50 C34859
SNOMED-CT 68 83252008
UMLS 72 C0028796
Sources

Summaries for Occupational Dermatitis

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MalaCards based summary : Occupational Dermatitis, also known as dermatitis, occupational, is related to dermatitis and contact dermatitis. An important gene associated with Occupational Dermatitis is KRT6B (Keratin 6B). The drugs Tacrolimus and Triamcinolone have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and liver.

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Related Diseases for Occupational Dermatitis

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Diseases related to Occupational Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
# Related Disease Score Top Affiliating Genes
1 dermatitis 30.4 PTGDR KLK7
2 contact dermatitis 10.6
3 allergic contact dermatitis 10.5
4 irritant dermatitis 10.4
5 skin disease 10.4
6 paresthesia 10.2
7 urticaria 10.2
8 leprosy 3 10.1
9 pulmonary alveolar microlithiasis 10.1
10 hearing loss, noise-induced 10.1
11 angina pectoris 10.1
12 blepharoconjunctivitis 10.1
13 laryngitis 10.1
14 conjunctivitis 10.1
15 48,xyyy 10.1
16 dentinogenesis imperfecta type 2 10.1
17 hansen's disease 10.1
18 ige responsiveness, atopic 10.1
19 dermatitis, atopic 10.0
20 vitiligo-associated multiple autoimmune disease susceptibility 6 9.9
21 vitiligo-associated multiple autoimmune disease susceptibility 1 9.9
22 exanthem 9.9
23 neurodermatitis 9.9
24 dermatomycosis 9.9
25 allergic asthma 9.9
26 neurofibromatosis, type ii 9.8
27 allergic rhinitis 9.8
28 pollen allergy 9.8
29 latex allergy 9.8
30 pulpitis 9.8
31 allergic hypersensitivity disease 9.8
32 tinea pedis 9.8
33 paronychia 9.8
34 angioedema 9.8
35 keratosis 9.8
36 skin carcinoma 9.8
37 rhinitis 9.8
38 mite infestation 9.8
39 scabies 9.8
40 bullous pemphigoid 9.8
41 rosacea 9.8
42 dermatophytosis 9.8
43 47,xyy 9.8
44 exfoliative dermatitis 9.8

Graphical network of the top 20 diseases related to Occupational Dermatitis:



Diseases related to Occupational Dermatitis
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Symptoms & Phenotypes for Occupational Dermatitis

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Drugs & Therapeutics for Occupational Dermatitis

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Drugs for Occupational Dermatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 19)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492 6473866
2
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
3
Clobetasol Approved, Experimental, Investigational Phase 4 25122-46-7, 25122-41-2 32798 5311051
4
Glycerol Approved, Investigational Phase 4 56-81-5 753
5
Mineral oil Approved, Vet_approved Phase 4 8042-47-5
6 Hormone Antagonists Phase 4
7 triamcinolone acetonide Phase 4
8 Triamcinolone hexacetonide Phase 4
9 Triamcinolone diacetate Phase 4
10 Hormones Phase 4
11 Anti-Inflammatory Agents Phase 4
12 Immunologic Factors Phase 4
13 glucocorticoids Phase 4
14 Immunosuppressive Agents Phase 4
15 Protective Agents Phase 4
16 Dermatologic Agents Phase 4
17 Emollients Phase 4
18 Calcineurin Inhibitors Phase 4
19 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Comparison of Efficacy of Glycerol, Two Topical Steroids, and a Topical Immune Modulator Against Experimentally Induced Skin Irritation Unknown status NCT00779792 Phase 4 clobetasol;triamcinolone acetonide;tacrolimus;glycerol;vehicle ointment (paraffin oil/soft white paraffin)
2 Hand Eczema Trial: A Randomised Clinical Trial of the Effect of Classification and Individual Counselling Among Health Care Workers With Hand Eczema Unknown status NCT01012453

Search NIH Clinical Center for Occupational Dermatitis

Cochrane evidence based reviews: dermatitis, occupational

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Genetic Tests for Occupational Dermatitis

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Anatomical Context for Occupational Dermatitis

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MalaCards organs/tissues related to Occupational Dermatitis:

41
Skin, Testes, Liver, Heart, Kidney
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Publications for Occupational Dermatitis

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Articles related to Occupational Dermatitis:

(show top 50) (show all 528)
# Title Authors PMID Year
1
Metal nanomaterials: Immune effects and implications of physicochemical properties on sensitization, elicitation, and exacerbation of allergic disease. 38
31195861 2019
2
Dermatitis among workers in Ontario: results from the Occupational Disease Surveillance System. 38
31320492 2019
3
Immunologic adverse reactions of β-blockers and the skin. 38
31384329 2019
4
Concomitant contact-allergic reactions to iodopropynyl butylcarbamate and iodine. 38
30663063 2019
5
Complement regulatory protein CD59a plays a protective role in immune liver injury of trichloroethylene-sensitized BALB/c mice. 38
30685621 2019
6
Contact allergy to methylchloroisothiazolinone/methylisothiazolinone in north-eastern Italy: a temporal trend from 1996 to 2016. 38
30697834 2019
7
New positive patch test reactions on day 7-The additional value of the day 7 patch test reading. 38
31116435 2019
8
Contact Dermatitis in Northeast Italy Mechanics (1996-2016). 38
30829802 2019
9
Occupational and Hand Dermatitis: a Practical Approach. 38
30171459 2019
10
Occupational allergic contact dermatitis caused by colophonium. 38
30229960 2019
11
Pilot study on a new concept of documenting the clinical relevance of patch test results in contact dermatitis patients. 38
30141249 2018
12
Transcriptional profiling of irritant contact dermatitis (ICD) in a mouse model identifies specific patterns of gene expression and immune-regulation. 38
30171875 2018
13
European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009-2014. 38
29468728 2018
14
Effectiveness of interventions for preventing occupational irritant hand dermatitis: a quantitative systematic review. 38
29894409 2018
15
Occupational dermatitis: How to identify the exposures, make the diagnosis, and treat the disease. 38
29698693 2018
16
Contact dermatitis and patch testing for the allergist. 38
29522811 2018
17
The Role of Cleaning Products in Epidemic Allergic Contact Dermatitis to Methylchloroisothiazolinone/Methylisothiazolinone. 38
29494393 2018
18
Footwear Contact Dermatitis: A Prospective Cross-Sectional Study of 108 Outpatients from Delhi, India. 38
29911525 2018
19
Nickel, chromium and cobalt: the relevant allergens in allergic contact dermatitis. Comparative study between two periods: 1995-2002 and 2003-2015. 38
29641698 2018
20
Occupational dermatoses reported in Brazil from 2007 to 2014. 38
29641693 2018
21
[Occupational allergic contact dermatitis: the role of occupational physician in the prevention.] 38
29916585 2017
22
Outbreak of Occupational Dermatitis Associated With Pyemotes ventricosus. 38
28445563 2017
23
Safer Soap: A Look at Harmful Ingredients Found in Hand Cleansers 38
30299009 2017
24
[The effect of complement C3a receptor antagonist in the kidney immune injury in trichloroethylene-sensitized mice]. 38
28511297 2017
25
Occupational dermatitis in hairdressers - influence of individual and environmental factors. 38
27709634 2017
26
Occupational contact allergy in bricklayers, tile setters etc. - Current spectrum of sensitization and recent time trends. 38
30402611 2017
27
Chromate and amine contact allergies in workers manufacturing precast concrete elements. 38
27659009 2016
28
Patch test results with rubber series in the European Surveillance System on Contact Allergies (ESSCA), 2013/14. 38
27402420 2016
29
Epidemiological analysis of occupational dermatitis notified in Brazil in the period 2007 to 2012. 38
28099592 2016
30
Friction from paper and cardboard causing occupational dermatitis in non-atopic individuals. 38
27040878 2016
31
Occupational Dermatitis in Instrumentalists: Note the Accessories. 38
27172315 2016
32
Occupational allergic contact dermatitis to chromium from cement: Estimating the size of the problem in Australia. 38
25367657 2015
33
Epidemiological data on airborne contact dermatitis - results of the IVDK. 38
26234324 2015
34
Occupational contact dermatitis caused by aniline epoxy resins in the aircraft industry. 38
25891194 2015
35
Occupational dermatitis in health care workers evaluated for suspected allergic contact dermatitis. 38
26172487 2015
36
The first Australian Baseline Series: Recommendations for patch testing in suspected contact dermatitis. 38
25196101 2015
37
[Quality management in occupational dermatology]. 38
25604435 2015
38
Association between cobalt allergy and dermatitis caused by leather articles--a questionnaire study. 38
25407465 2015
39
Fingertip dermatitis: occupational acrylate cross reaction. 38
25056224 2014
40
Rosmarinus officinalis L. as cause of contact dermatitis. 38
23827646 2014
41
Cost-of-illness of patients with contact dermatitis in Denmark. 38
24750019 2014
42
A study of morbidity pattern among iron and steel workers from an industry in central India. 38
25598617 2014
43
Resolution of occupational dermatitis related to manganese exposures. 38
25207694 2014
44
Isothiazolinones in commercial products at Danish workplaces. 38
24850171 2014
45
Skin irritability to sodium lauryl sulfate is associated with increased positive patch test reactions. 38
24593017 2014
46
Cases of occupational dermatitis and asthma in beauticians that were reported to The Health and Occupation Research (THOR) network from 1996 to 2011. 38
24934913 2014
47
[Definition and psychopathology of chronic hand dermatitis]. 38
24953619 2014
48
Two-year follow-up survey of patients with allergic contact dermatitis from an occupational cohort: is the prognosis dependent on the omnipresence of the allergen? 38
24359102 2014
49
[Hand and occupational diseases]. 38
24134812 2013
50
Risk factors of polysensitization to contact allergens. 38
23647229 2013
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Variations for Occupational Dermatitis

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Expression for Occupational Dermatitis

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Search GEO for disease gene expression data for Occupational Dermatitis.
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Pathways for Occupational Dermatitis

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GO Terms for Occupational Dermatitis

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Biological processes related to Occupational Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoskeleton organization GO:0007010 9.16 PCLO KRT6B
2 positive regulation of cytosolic calcium ion concentration GO:0007204 8.96 PTGDR C3AR1
3 inflammatory response GO:0006954 8.8 PTGDR PLA2G2D C3AR1
Sources

Sources for Occupational Dermatitis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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