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MCID: OCC001
MIFTS: 29

Occupational Dermatitis

Categories: Immune diseases, Skin diseases
Genes Tissues Related diseases Publications Drugs
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Aliases & Classifications for Occupational Dermatitis

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MalaCards integrated aliases for Occupational Dermatitis:

Name: Occupational Dermatitis 12 15 17
Dermatitis, Occupational 43 71
Occupational Allergic Contact Dermatitis 12
Occupational Eczema 12

Classifications:

MalaCards categories:
Anatomical: Skin diseases Immune diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:4404
MeSH 43 D009783
NCIt 49 C34859
SNOMED-CT 67 83252008
UMLS 71 C0028796
Sources

Summaries for Occupational Dermatitis

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MalaCards based summary : Occupational Dermatitis, also known as dermatitis, occupational, is related to dermatitis and contact dermatitis. An important gene associated with Occupational Dermatitis is FLG (Filaggrin). The drugs Tacrolimus and Mineral oil have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and liver.

Sources

Related Diseases for Occupational Dermatitis

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Diseases related to Occupational Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
# Related Disease Score Top Affiliating Genes
1 dermatitis 11.0
2 contact dermatitis 10.6
3 allergic contact dermatitis 10.5
4 irritant dermatitis 10.4
5 skin disease 10.4
6 paresthesia 10.2
7 urticaria 10.2
8 leprosy 3 10.1
9 hearing loss, noise-induced 10.1
10 angina pectoris 10.1
11 blepharoconjunctivitis 10.1
12 laryngitis 10.1
13 conjunctivitis 10.1
14 48,xyyy 10.1
15 cytokine deficiency 10.1
16 dentinogenesis imperfecta type 2 10.1
17 hansen's disease 10.1
18 ige responsiveness, atopic 10.1
19 dermatitis, atopic 10.0
20 pachyonychia congenita 1 10.0 KRT6B FLG
21 vitiligo-associated multiple autoimmune disease susceptibility 6 9.9
22 vitiligo-associated multiple autoimmune disease susceptibility 1 9.9
23 exanthem 9.9
24 neurodermatitis 9.9
25 yaws 9.9 PLA2G2D MMD
26 palmoplantar keratoderma, epidermolytic 9.9 KRT6B FLG
27 dermatomycosis 9.9
28 allergic asthma 9.9
29 moyamoya disease 1 9.8 PCLO MMD
30 neurofibromatosis, type ii 9.8
31 allergic rhinitis 9.8
32 pollen allergy 9.8
33 latex allergy 9.8
34 pulpitis 9.8
35 allergic hypersensitivity disease 9.8
36 tinea pedis 9.8
37 paronychia 9.8
38 angioedema 9.8
39 keratosis 9.8
40 skin carcinoma 9.8
41 rhinitis 9.8
42 mite infestation 9.8
43 scabies 9.8
44 bullous pemphigoid 9.8
45 rosacea 9.8
46 dermatophytosis 9.8
47 47,xyy 9.8
48 epidermolytic hyperkeratosis 9.7 KRT6B FLG

Graphical network of the top 20 diseases related to Occupational Dermatitis:



Diseases related to Occupational Dermatitis
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Symptoms & Phenotypes for Occupational Dermatitis

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Drugs & Therapeutics for Occupational Dermatitis

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Drugs for Occupational Dermatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 16)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492 6473866
2
Mineral oil Approved, Vet_approved Phase 4 8042-47-5
3
Glycerol Approved, Investigational Phase 4 56-81-5 753
4
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
5
Clobetasol Approved, Experimental, Investigational Phase 4 25122-46-7, 25122-41-2 32798 5311051
6 Hormone Antagonists Phase 4
7 triamcinolone acetonide Phase 4
8 Immunosuppressive Agents Phase 4
9 Protective Agents Phase 4
10 Triamcinolone diacetate Phase 4
11 glucocorticoids Phase 4
12 Calcineurin Inhibitors Phase 4
13 Anti-Inflammatory Agents Phase 4
14 Hormones Phase 4
15 Immunologic Factors Phase 4
16 Triamcinolone hexacetonide Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Comparison of Efficacy of Glycerol, Two Topical Steroids, and a Topical Immune Modulator Against Experimentally Induced Skin Irritation Unknown status NCT00779792 Phase 4 clobetasol;triamcinolone acetonide;tacrolimus;glycerol;vehicle ointment (paraffin oil/soft white paraffin)
2 Hand Eczema Trial: A Randomised Clinical Trial of the Effect of Classification and Individual Counselling Among Health Care Workers With Hand Eczema Unknown status NCT01012453
3 Hand Dermatitis in the Care and Hospital Staff of the Brest CHRU: State of Play Completed NCT04136574

Search NIH Clinical Center for Occupational Dermatitis

Cochrane evidence based reviews: dermatitis, occupational

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Genetic Tests for Occupational Dermatitis

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Anatomical Context for Occupational Dermatitis

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MalaCards organs/tissues related to Occupational Dermatitis:

40
Skin, Testes, Liver, Heart, Kidney
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Publications for Occupational Dermatitis

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Articles related to Occupational Dermatitis:

(show top 50) (show all 531)
# Title Authors PMID Year
1
The methylisothiazolinone epidemic goes along with changing patients' characteristics - After cosmetics, industrial applications are the focus. 61
31599977 2020
2
Cutaneous sensitization to aziridine preceding the onset of occupational asthma. 61
32002545 2020
3
Metal nanomaterials: Immune effects and implications of physicochemical properties on sensitization, elicitation, and exacerbation of allergic disease. 61
31195861 2019
4
Assessment of occupational exposure and spectrum of contact sensitization in metalworkers with occupational dermatitis: results of a cohort study within the OCCUDERM project. 61
31804740 2019
5
New positive patch test reactions on day 7-The additional value of the day 7 patch test reading. 61
31116435 2019
6
Dermatitis among workers in Ontario: results from the Occupational Disease Surveillance System. 61
31320492 2019
7
Immunologic adverse reactions of β-blockers and the skin. 61
31384329 2019
8
[Allergic contact dermatitis to cobalt and nickel in a metal industry worker. Case report and literature review]. 61
31606022 2019
9
Concomitant contact-allergic reactions to iodopropynyl butylcarbamate and iodine. 61
30663063 2019
10
Complement regulatory protein CD59a plays a protective role in immune liver injury of trichloroethylene-sensitized BALB/c mice. 61
30685621 2019
11
Contact allergy to methylchloroisothiazolinone/methylisothiazolinone in north-eastern Italy: a temporal trend from 1996 to 2016. 61
30697834 2019
12
Contact Dermatitis in Northeast Italy Mechanics (1996-2016). 61
30829802 2019
13
Occupational and Hand Dermatitis: a Practical Approach. 61
30171459 2019
14
Occupational allergic contact dermatitis caused by colophonium. 61
30229960 2019
15
Transcriptional profiling of irritant contact dermatitis (ICD) in a mouse model identifies specific patterns of gene expression and immune-regulation. 61
30171875 2018
16
Pilot study on a new concept of documenting the clinical relevance of patch test results in contact dermatitis patients. 61
30141249 2018
17
European Surveillance System on Contact Allergies (ESSCA): polysensitization, 2009-2014. 61
29468728 2018
18
Effectiveness of interventions for preventing occupational irritant hand dermatitis: a quantitative systematic review. 61
29894409 2018
19
Occupational dermatitis: How to identify the exposures, make the diagnosis, and treat the disease. 61
29698693 2018
20
Contact dermatitis and patch testing for the allergist. 61
29522811 2018
21
The Role of Cleaning Products in Epidemic Allergic Contact Dermatitis to Methylchloroisothiazolinone/Methylisothiazolinone. 61
29494393 2018
22
Footwear Contact Dermatitis: A Prospective Cross-Sectional Study of 108 Outpatients from Delhi, India. 61
29911525 2018
23
Occupational dermatoses reported in Brazil from 2007 to 2014. 61
29641693 2018
24
Nickel, chromium and cobalt: the relevant allergens in allergic contact dermatitis. Comparative study between two periods: 1995-2002 and 2003-2015. 61
29641698 2018
25
[Occupational allergic contact dermatitis: the role of occupational physician in the prevention.] 61
29916585 2017
26
Outbreak of Occupational Dermatitis Associated With Pyemotes ventricosus. 61
28445563 2017
27
Safer Soap: A Look at Harmful Ingredients Found in Hand Cleansers 61
30299009 2017
28
[The effect of complement C3a receptor antagonist in the kidney immune injury in trichloroethylene-sensitized mice]. 61
28511297 2017
29
Occupational dermatitis in hairdressers - influence of individual and environmental factors. 61
27709634 2017
30
Occupational contact allergy in bricklayers, tile setters etc. - Current spectrum of sensitization and recent time trends. 61
30402611 2017
31
Chromate and amine contact allergies in workers manufacturing precast concrete elements. 61
27659009 2016
32
Patch test results with rubber series in the European Surveillance System on Contact Allergies (ESSCA), 2013/14. 61
27402420 2016
33
Epidemiological analysis of occupational dermatitis notified in Brazil in the period 2007 to 2012. 61
28099592 2016
34
Friction from paper and cardboard causing occupational dermatitis in non-atopic individuals. 61
27040878 2016
35
Occupational Dermatitis in Instrumentalists: Note the Accessories. 61
27172315 2016
36
Occupational allergic contact dermatitis to chromium from cement: Estimating the size of the problem in Australia. 61
25367657 2015
37
Epidemiological data on airborne contact dermatitis - results of the IVDK. 61
26234324 2015
38
Occupational contact dermatitis caused by aniline epoxy resins in the aircraft industry. 61
25891194 2015
39
Occupational dermatitis in health care workers evaluated for suspected allergic contact dermatitis. 61
26172487 2015
40
The first Australian Baseline Series: Recommendations for patch testing in suspected contact dermatitis. 61
25196101 2015
41
[Quality management in occupational dermatology]. 61
25604435 2015
42
Association between cobalt allergy and dermatitis caused by leather articles--a questionnaire study. 61
25407465 2015
43
Fingertip dermatitis: occupational acrylate cross reaction. 61
25056224 2014
44
Rosmarinus officinalis L. as cause of contact dermatitis. 61
23827646 2014
45
Resolution of occupational dermatitis related to manganese exposures. 61
25207694 2014
46
Cost-of-illness of patients with contact dermatitis in Denmark. 61
24750019 2014
47
A study of morbidity pattern among iron and steel workers from an industry in central India. 61
25598617 2014
48
Isothiazolinones in commercial products at Danish workplaces. 61
24850171 2014
49
Cases of occupational dermatitis and asthma in beauticians that were reported to The Health and Occupation Research (THOR) network from 1996 to 2011. 61
24934913 2014
50
Skin irritability to sodium lauryl sulfate is associated with increased positive patch test reactions. 61
24593017 2014
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Variations for Occupational Dermatitis

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Expression for Occupational Dermatitis

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Search GEO for disease gene expression data for Occupational Dermatitis.
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Pathways for Occupational Dermatitis

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GO Terms for Occupational Dermatitis

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Biological processes related to Occupational Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornification GO:0070268 8.62 KRT6B FLG
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Sources for Occupational Dermatitis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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