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MCID: OCC001
MIFTS: 36

Occupational Dermatitis

Categories: Skin diseases, Immune diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Occupational Dermatitis

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MalaCards integrated aliases for Occupational Dermatitis:

Name: Occupational Dermatitis 12 15
Dermatitis, Occupational 44 73
Occupational Allergic Contact Dermatitis 12
Occupational Eczema 12

Classifications:

MalaCards categories:
Anatomical: Skin diseases Immune diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:4404
MeSH 44 D009783
NCIt 50 C34859
UMLS 73 C0028796
Sources

Summaries for Occupational Dermatitis

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MalaCards based summary : Occupational Dermatitis, also known as dermatitis, occupational, is related to dermatitis and complement component 3 deficiency. An important gene associated with Occupational Dermatitis is C3AR1 (Complement C3a Receptor 1), and among its related pathways/superpathways is Staphylococcus aureus infection. The drugs Glycerol and Clobetasol have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and heart, and related phenotype is homeostasis/metabolism.

Sources

Related Diseases for Occupational Dermatitis

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Diseases related to Occupational Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 21)
# Related Disease Score Top Affiliating Genes
1 dermatitis 10.8
2 complement component 3 deficiency 10.5 C3 C3AR1
3 sphingolipidosis 10.2 GBA SMPD1
4 netherton syndrome 10.2 DSG1 GBA KLK7
5 orthostatic proteinuria 10.1 ALB C3
6 aspiration pneumonia 10.1 ALB MMP8
7 ascending cholangitis 10.1 ALB C3
8 contact dermatitis 10.0
9 lemierre's syndrome 10.0 ALK C3
10 hypersensitivity reaction type iii disease 10.0 ALB C3
11 dependent personality disorder 9.8 KNTC1 SMPD1
12 asthma 9.8
13 skin disease 9.8
14 allergic contact dermatitis 9.8
15 membranoproliferative glomerulonephritis 9.8 ALB C3
16 exanthem 9.7
17 paronychia 9.7
18 neurodermatitis 9.7
19 rhinitis 9.7
20 scabies 9.7
21 appendicitis 9.5 ALB MMP8

Graphical network of the top 20 diseases related to Occupational Dermatitis:



Diseases related to Occupational Dermatitis
Sources

Symptoms & Phenotypes for Occupational Dermatitis

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MGI Mouse Phenotypes related to Occupational Dermatitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.28 ALB ALK C3 C3AR1 GBA KNTC1
Sources

Drugs & Therapeutics for Occupational Dermatitis

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Drugs for Occupational Dermatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Glycerol Approved, Investigational Phase 4 56-81-5 753
2
Clobetasol Approved, Investigational Phase 4 25122-46-7, 25122-41-2 32798 5311051
3
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
4
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492
5 triamcinolone acetonide Phase 4
6 glucocorticoids Phase 4
7 Hormone Antagonists Phase 4
8 Triamcinolone diacetate Phase 4
9 Triamcinolone hexacetonide Phase 4
10 Hormones Phase 4
11 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
12 Immunosuppressive Agents Phase 4
13 Protective Agents Phase 4
14 Anti-Inflammatory Agents Phase 4
15 Calcineurin Inhibitors Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Efficacy of Glycerol, Two Topical Steroids, and a Topical Immune Modulator Against Skin Irritation Unknown status NCT00779792 Phase 4 clobetasol;triamcinolone acetonide;tacrolimus;glycerol;vehicle ointment (paraffin oil/soft white paraffin)

Search NIH Clinical Center for Occupational Dermatitis

Cochrane evidence based reviews: dermatitis, occupational

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Genetic Tests for Occupational Dermatitis

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Anatomical Context for Occupational Dermatitis

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MalaCards organs/tissues related to Occupational Dermatitis:

41
Skin, Testes, Heart
Sources

Publications for Occupational Dermatitis

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Articles related to Occupational Dermatitis:

(show top 50) (show all 204)
# Title Authors Year
1
Occupational dermatitis: How to identify the exposures, make the diagnosis, and treat the disease. ( 29698693 )
2018
2
Outbreak of Occupational Dermatitis Associated With Pyemotes ventricosus. ( 28445563 )
2017
3
Occupational dermatitis in hairdressersa88-a88influence of individual and environmental factors. ( 27709634 )
2016
4
Epidemiological analysis of occupational dermatitis notified in Brazil in the period 2007 to 2012. ( 28099592 )
2016
5
Friction from paper and cardboard causing occupational dermatitis in non-atopic individuals. ( 27040878 )
2016
6
Occupational Dermatitis in Instrumentalists: Note the Accessories. ( 27172315 )
2016
7
Occupational dermatitis in health care workers evaluated for suspected allergic contact dermatitis. ( 26172487 )
2015
8
Cases of occupational dermatitis and asthma in beauticians that were reported to The Health and Occupation Research (THOR) network from 1996 to 2011. ( 24934913 )
2014
9
Resolution of occupational dermatitis related to manganese exposures. ( 25207694 )
2014
10
Occupational dermatitis in hairdressers: do they claim workers' compensation? ( 22957536 )
2013
11
Recent advances in occupational dermatitis. ( 23324811 )
2013
12
Management of occupational dermatitis in healthcare workers: a systematic review. ( 22034544 )
2012
13
Occupational dermatitis in workers exposed to detergents, disinfectants, and antiseptics. ( 22783559 )
2012
14
Allergic contact dermatitis among construction workers detected in a clinic that did not specialize in occupational dermatitis. ( 22892770 )
2012
15
Occupational dermatitis caused by Lyngbya majuscula in Australia. ( 22182392 )
2012
16
Prevention of occupational dermatitis. ( 21329572 )
2011
17
Occupational dermatitis to epoxydic and phenolic resins. ( 19349256 )
2009
18
Effectiveness of skin protection creams in the prevention of occupational dermatitis: results of a randomized, controlled trial. ( 18972125 )
2009
19
Management of occupational dermatitis. ( 19580930 )
2009
20
Occupational dermatitis because of carnation. ( 18186757 )
2008
21
Tertiary individual prevention of occupational skin diseases: a decade's experience with recalcitrant occupational dermatitis. ( 18239930 )
2008
22
Occupational dermatitis in a hairdresser. ( 17717371 )
2007
23
Allergic occupational dermatitis due to Ceropegia woodii (string of hearts). ( 17577387 )
2007
24
Occupational dermatitis and allergic respiratory diseases in Finnish metalworking machinists. ( 17392449 )
2007
25
Occupational dermatitis related to chromium and cobalt: experience of dermatologists (EPIDERM) and occupational physicians (OPRA) in the U.K. over an 11-year period (1993-2004). ( 17596174 )
2007
26
Glove selection as personal protective equipment and occupational dermatitis among Japanese midwives. ( 16484761 )
2006
27
Surveillance and assessment of occupational dermatitis using Rhode Island workers' compensation data 1998 to 2002. ( 16844536 )
2006
28
Persistent post-occupational dermatitis: report of five cases. ( 16710586 )
2006
29
Incidence rates, costs, severity, and work-related factors of occupational dermatitis: a workers' compensation analysis of Oregon, 1990-1997. ( 15967917 )
2005
30
Stethoscope dermatitis: an occupational dermatitis of medical personnel. ( 15672719 )
2004
31
Persistent post-occupational dermatitis. ( 15606653 )
2004
32
Occupational dermatitis in a milk industry worker due to Kathon CG. ( 15473332 )
2004
33
Contact sensitizations in metalworkers with occupational dermatitis exposed to water-based metalworking fluids: results of the research project "FaSt". ( 15538620 )
2004
34
Occupational dermatitis in a milk industry worker due to Kathon CG. ( 15842069 )
2004
35
Occupational dermatitis from soldering flux. ( 15295911 )
2004
36
Effectiveness of skin protection creams as a preventive measure in occupational dermatitis: a critical update according to criteria of evidence-based medicine. ( 12684811 )
2003
37
Occupational dermatitis from a one-component naphthalene type epoxy adhesive. ( 11926518 )
2002
38
Epidemic occupational dermatitis caused by Pronematus davisi (Acari: Tydeidae). ( 12000406 )
2002
39
The prevalence of occupational dermatitis in the UK printing industry. ( 12107299 )
2002
40
Occupational dermatitis in dental personnel: contact dermatitis with special reference to (meth)acrylates in 174 patients. ( 11553142 )
2001
41
Occupational dermatitis in a highly industrialized Italian region: the experience of four occupational health departments. ( 11327404 )
2001
42
The presence of some yeasts species in occupational dermatitis. ( 11845472 )
2000
43
2 cases of occupational dermatitis due to mercury vapor from a broken sphygmomanometer. ( 10985639 )
2000
44
Is occupational dermatitis being taken seriously by UK industries? ( 10436560 )
1999
45
Occupational dermatitis in Sheffield: a preliminary study. ( 10208522 )
1999
46
Occupational dermatitis to ultraviolet-cured acrylic-based inks in computer hard disc manufacturing. ( 9744912 )
1998
47
Occupational dermatitis in Danish gardeners and greenhouse workers (II). Etiological factors. ( 9504241 )
1998
48
Occupational dermatitis in a silk-screen maker. ( 9686987 )
1998
49
Occupational dermatitis causing days away from work in U.S. private industry, 1993. ( 9816414 )
1998
50
Occupational dermatitis in Danish gardeners and greenhouse workers (III). Compositae-related symptoms. ( 9536405 )
1998
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Variations for Occupational Dermatitis

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Expression for Occupational Dermatitis

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Search GEO for disease gene expression data for Occupational Dermatitis.
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Pathways for Occupational Dermatitis

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Pathways related to Occupational Dermatitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Staphylococcus aureus infection 37
10.55 C3 C3AR1 DSG1
Sources

GO Terms for Occupational Dermatitis

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Cellular components related to Occupational Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.1 ALB C3 GBA KLK7 MMP8 SMPD1

Biological processes related to Occupational Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neutrophil degranulation GO:0043312 9.62 C3 C3AR1 DSG1 MMP8
2 glycosphingolipid metabolic process GO:0006687 9.4 GBA SMPD1
3 negative regulation of MAP kinase activity GO:0043407 9.37 GBA SMPD1
4 positive regulation of vascular endothelial growth factor production GO:0010575 9.26 C3 C3AR1
5 ceramide biosynthetic process GO:0046513 9.16 GBA SMPD1
6 positive regulation of protein dephosphorylation GO:0035307 8.96 GBA SMPD1
7 termination of signal transduction GO:0023021 8.62 GBA SMPD1

Molecular functions related to Occupational Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 toxic substance binding GO:0015643 8.62 ALB DSG1
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Sources for Occupational Dermatitis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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