MCID: OCC001
MIFTS: 30

Occupational Dermatitis

Categories: Immune diseases, Skin diseases
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Aliases & Classifications for Occupational Dermatitis

MalaCards integrated aliases for Occupational Dermatitis:

Name: Occupational Dermatitis 11 14 16
Dermatitis, Occupational 43 71
Occupational Allergic Contact Dermatitis 11
Occupational Eczema 11

Classifications:



External Ids:

Disease Ontology 11 DOID:4404
MeSH 43 D009783
NCIt 49 C34859
SNOMED-CT 68 200780008
UMLS 71 C0028796

Summaries for Occupational Dermatitis

MalaCards based summary: Occupational Dermatitis, also known as dermatitis, occupational, is related to dermatitis and contact dermatitis. An important gene associated with Occupational Dermatitis is FLG (Filaggrin). The drugs Triamcinolone and Glycerin have been mentioned in the context of this disorder. Affiliated tissues include skin, lymph node and kidney, and related phenotype is Increased shRNA abundance (Z-score > 2).

Related Diseases for Occupational Dermatitis

Diseases related to Occupational Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 81)
# Related Disease Score Top Affiliating Genes
1 dermatitis 30.8 KLK7 IL31 FLG
2 contact dermatitis 30.7 IL31 FLG
3 irritant dermatitis 30.5 IL31 FLG
4 allergic contact dermatitis 30.4 IL31 FLG
5 neurodermatitis 29.8 IL31 FLG
6 dermatitis, atopic 29.7 KLK7 IL31 FLG
7 skin disease 29.7 KLK7 IL31 FLG C3AR1
8 scabies 29.6 IL31 FLG
9 urticaria 10.3
10 gastric antral vascular ectasia 10.3
11 paresthesia 10.3
12 ige responsiveness, atopic 10.1
13 dentinogenesis imperfecta 1 10.1
14 leprosy 3 10.1
15 congenital lipomatous overgrowth, vascular malformations, and epidermal nevi 10.1
16 hearing loss, noise-induced 10.1
17 angina pectoris 10.1
18 keratomalacia 10.1
19 blepharoconjunctivitis 10.1
20 laryngitis 10.1
21 photoallergic dermatitis 10.1
22 hypokalemia 10.1
23 conjunctivitis 10.1
24 diffuse idiopathic skeletal hyperostosis 10.1
25 cytokine deficiency 10.1
26 exanthem 10.1
27 pachyonychia congenita 1 10.0 KRT6B FLG
28 photoparoxysmal response 1 10.0
29 ichthyosis, x-linked 10.0 FLG ARSL
30 peeling skin syndrome 10.0 KLK7 FLG
31 vitiligo-associated multiple autoimmune disease susceptibility 6 10.0
32 vitiligo-associated multiple autoimmune disease susceptibility 1 10.0
33 glass syndrome 10.0
34 occupational asthma 10.0
35 respiratory failure 10.0
36 paronychia 10.0
37 neurotic excoriation 10.0
38 ichthyosis, congenital, autosomal recessive 4b 10.0 KLK7 FLG
39 netherton syndrome 9.9 KLK7 FLG
40 epidermolysis bullosa simplex 9.9 KRT6B FLG
41 ichthyosis vulgaris 9.9 KLK7 FLG
42 eczema herpeticum 9.9 IL31 FLG
43 mite infestation 9.9 IL31 FLG
44 parasitic ectoparasitic infectious disease 9.9 IL31 FLG
45 neurodegeneration with brain iron accumulation 2a 9.9
46 brucellosis 9.9
47 allergic asthma 9.9
48 skin atrophy 9.9 IL31 FLG
49 down syndrome 9.8
50 ceroid lipofuscinosis, neuronal, 5 9.8

Graphical network of the top 20 diseases related to Occupational Dermatitis:



Diseases related to Occupational Dermatitis

Symptoms & Phenotypes for Occupational Dermatitis

GenomeRNAi Phenotypes related to Occupational Dermatitis according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.32 EYS
2 Increased shRNA abundance (Z-score > 2) GR00366-A-101 9.32 ARSL
3 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.32 EYS
4 Increased shRNA abundance (Z-score > 2) GR00366-A-16 9.32 EYS
5 Increased shRNA abundance (Z-score > 2) GR00366-A-166 9.32 EYS
6 Increased shRNA abundance (Z-score > 2) GR00366-A-173 9.32 EYS
7 Increased shRNA abundance (Z-score > 2) GR00366-A-2 9.32 ARSL
8 Increased shRNA abundance (Z-score > 2) GR00366-A-203 9.32 ARSL
9 Increased shRNA abundance (Z-score > 2) GR00366-A-37 9.32 EYS
10 Increased shRNA abundance (Z-score > 2) GR00366-A-94 9.32 ARSL

Drugs & Therapeutics for Occupational Dermatitis

Drugs for Occupational Dermatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
2
Glycerin Approved, Investigational Phase 4 56-81-5 753
3
Tacrolimus Approved, Investigational Phase 4 104987-11-3 6473866 445643
4
Clobetasol Approved, Experimental, Investigational Phase 4 25122-46-7, 25122-41-2 2791 5311051 32798
5
Mineral oil Approved, Vet_approved Phase 4 8042-47-5
6 Hormones Phase 4
7 Calcineurin Inhibitors Phase 4
8 Hormone Antagonists Phase 4
9
Triamcinolone hexacetonide Phase 4
10
Triamcinolone diacetate Phase 4
11
Triamcinolone Acetonide Phase 4 6436
12 Anti-Inflammatory Agents Phase 4
13 glucocorticoids Phase 4
14 Emollients Phase 4
15 Immunosuppressive Agents Phase 4
16 Dermatologic Agents Phase 4
17 Immunologic Factors Phase 4
18 Protective Agents Phase 4

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Comparison of Efficacy of Glycerol, Two Topical Steroids, and a Topical Immune Modulator Against Experimentally Induced Skin Irritation Unknown status NCT00779792 Phase 4 clobetasol;triamcinolone acetonide;tacrolimus;glycerol;vehicle ointment (paraffin oil/soft white paraffin)

Search NIH Clinical Center for Occupational Dermatitis

Cochrane evidence based reviews: dermatitis, occupational

Genetic Tests for Occupational Dermatitis

Anatomical Context for Occupational Dermatitis

Organs/tissues related to Occupational Dermatitis:

MalaCards : Skin, Lymph Node, Kidney, Liver, Eye

Publications for Occupational Dermatitis

Articles related to Occupational Dermatitis:

(show top 50) (show all 1078)
# Title Authors PMID Year
1
Occupational allergic contact dermatitis caused by colophonium, an unsuspected sensitizer in a petrochemical worker. 62
36050864 2022
2
Non-occupational allergic contact dermatitis from epoxy resin in children's games. 62
36444522 2022
3
Occupational allergic contact dermatitis to Piperamido Nitrotoluene in pharmaceutical workers: A case series. 62
35837878 2022
4
Nonoccupational Allergic Contact Dermatitis to 4-Acryloylmorpholine in Smartwatch Screen Protectors Glue. 62
35674508 2022
5
Occupational allergic contact dermatitis to sodium metabisulfite in shredded coconut. 62
35715879 2022
6
Contact sensitizations in massage therapists with occupational contact dermatitis: Patch test data of the Information Network of Departments of Dermatology, 2008-2020. 62
36088572 2022
7
Occupational allergic contact dermatitis to dicylohexylamine in a metalworking fluid. 62
35429169 2022
8
Contact eczema induced by hybrid manicure. The role of acrylates as a causative factor. 62
36090720 2022
9
The additive value of patch testing non-commercial test substances and patients' own products in a clinic of occupational dermatology. 62
35864599 2022
10
Occupational allergic contact dermatitis caused by tetrahydroxypropyl ethylenediamine in hand disinfectants. 62
35320594 2022
11
Outbreak of occupational allergic contact dermatitis from a smartphone screen protector glue. 62
35184294 2022
12
The 2-Methoxymethyl Modification of p -Phenylenediamine Reduces the Sensitization Risk for Hairdressers to Hair Dyes-An Occupational Hand Exposure-Based Risk Assessment. 62
35777963 2022
13
[Translated article] Contact Dermatitis to Allergens in the Spanish Standard Series: Patch Test Findings in the South of Gran Canaria. 62
35748001 2022
14
Contact Dermatitis to Allergens in the Spanish Standard Series: Patch Test Findings in the South of Gran Canaria. 62
35292236 2022
15
Occupational allergic contact dermatitis caused by shellac. 62
35194808 2022
16
Nature-derived epoxy resins: Synthesis, allergenicity, and thermosetting properties of pinoresinol diglycidyl ether. 62
35465773 2022
17
Keratolysis exfoliativa-like eruption induced by ranolazine. 62
35399369 2022
18
Quality of Life of Healthcare Workers Suffering from Occupational Contact Dermatitis. 62
33706687 2022
19
Contact Dermatitis: Classifications and Management. 62
34264448 2021
20
Should Paraben Mix Be Removed from The European Baseline Series. 62
34990349 2021
21
Occupational allergic contact dermatitis: A 24-year, retrospective cohort study from Turkey. 62
34263479 2021
22
Occupational contact dermatitis in painters and varnishers: Data from the Information Network of Departments of Dermatology (IVDK), 2000 to 2019. 62
34260080 2021
23
Occupational allergic contact dermatitis caused by thiourea in a jewelry cleaner. 62
34137044 2021
24
Contact Allergy to Ammonium Persulfate: An Epidemiologic Study of 2138 Consecutive Dermatitis Patients. 62
35283527 2021
25
Contact Dermatitis in Construction Workers in Northeastern Italian Patch Test Database Between 1996 and 2016. 62
34807530 2021
26
Occupational allergic contact dermatitis to dibutyl maleate and dibutyl fumarate present in a safety shoe: A reason for concern? 62
34028835 2021
27
Occupational allergic contact dermatitis to 4,4-methylenebis(cyclohexylisocyanate). 62
33966278 2021
28
Occupational allergic contact dermatitis from hydrangea: an underdiagnosed allergy? 62
33890738 2021
29
Ayurveda intervention for brass-induced heavy metal toxicity: A report from the single-arm pilot study. 62
34690043 2021
30
Occupational allergic contact dermatitis from ammonium persulfate in a hairdresser. 62
33797126 2021
31
Recycled products are not always skin-friendly: Occupational dermatitis due to recycled plastic. 62
34334234 2021
32
Acrylates as a significant cause of allergic contact dermatitis: new sources of exposure. 62
34658693 2021
33
Occupational Dermatitis and Urticaria. 62
34225899 2021
34
Occupational allergic contact dermatitis caused by nalmefene. 62
33527420 2021
35
Prevalence and Risk Factor of Occupational Skin Complaints among Male Tannery Workers of Kanpur, India. 62
34759391 2021
36
Frequency of sensitization to the individual fragrances of fragrance mix I and II according to the factors included in the MOAHLFA index. 62
33534191 2021
37
Candidate Allergens for Inclusion in the Spanish Standard Series Based on Data from the Spanish Contact Dermatitis Registry. 62
34029518 2021
38
Occupational allergic contact dermatitis to isobornyl acrylate present in cell phone screen protectors. 62
33222188 2021
39
What Is New in Occupational Allergic Contact Dermatitis in the Year of the COVID Pandemic? 62
33779825 2021
40
Occupational allergic contact dermatitis in a cohort of 458 consecutive dermatitis patients: A case series of 17 patients. 62
32497697 2021
41
Occupational Dermatitis in Welding: Does Nickel Exposure Account for Higher Rates in Women? Analysis of a Canadian Cohort. 62
32430497 2021
42
Occupational allergic contact dermatitis in a basket player due to phenolic resins. 62
33609285 2021
43
Occupational dermatitis to facial personal protective equipment in health care workers: A systematic review. 62
33011325 2021
44
Methylchloroisothiazolinone/methylisothiazolinone and methylisothiazolinone contact allergy: A 24-year, single-center, retrospective cohort study from Turkey. 62
32691417 2021
45
Contact sensitization in metalworkers: Data from the information network of departments of dermatology (IVDK), 2010-2018. 62
32776554 2020
46
Occupational allergic contact dermatitis and contact urticaria caused by indoor plants in plant keepers. 62
32588436 2020
47
Relevance of contact sensitizations in occupational dermatitis patients with special focus on patch testing of workplace materials. 62
32829502 2020
48
Occupational allergic contact dermatitis from multiple essential oils. 62
32564383 2020
49
Occupational allergic contact dermatitis due to undeclared benzisothiazolinone in an emulsifying oil. 62
32297347 2020
50
Demographic and clinical features and subsectoral differences in occupational contact allergens in clothing manufacturing workers. 62
32914884 2020

Variations for Occupational Dermatitis

Expression for Occupational Dermatitis

Search GEO for disease gene expression data for Occupational Dermatitis.

Pathways for Occupational Dermatitis

GO Terms for Occupational Dermatitis

Cellular components related to Occupational Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornified envelope GO:0001533 8.92 KLK7 FLG

Molecular functions related to Occupational Dermatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of skin epidermis GO:0030280 8.92 KRT6B FLG

Sources for Occupational Dermatitis

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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