COMA
MCID: OCL069
MIFTS: 53

Ocular Motor Apraxia (COMA)

Categories: Eye diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Ocular Motor Apraxia

MalaCards integrated aliases for Ocular Motor Apraxia:

Name: Ocular Motor Apraxia 57
Coma 57 53 54 43
Oculomotor Apraxia, Congenital, Cogan-Type 57 13
Oculomotor Apraxia, Cogan Type 57 59
Saccade Initiation Failure, Congenital 57
Saccade Initiation Failure Congenital 53
Oculomotor Apraxia, Cogan Type; Coma 57
Ocular Motor Apraxia, Cogan Type 59
Oculomotor Apraxia Cogan Type 53
Congenital Oculomotor Apraxia 53
Cogan's Syndrome Type 2 53
Oculomotor Apraxia 72
Comatose 72

Characteristics:

Orphanet epidemiological data:

59
ocular motor apraxia, cogan type
Inheritance: Autosomal recessive; Prevalence: <1/1000000 (Worldwide); Age of onset: Childhood;

OMIM:

57
Inheritance:
autosomal recessive

Miscellaneous:
ocular movement dysfunction improves with age


HPO:

32
ocular motor apraxia:
Inheritance autosomal recessive inheritance


Classifications:

Orphanet: 59  
Rare eye diseases


External Ids:

OMIM 57 257550
ICD10 33 R40.2
MESH via Orphanet 45 C537423
ICD10 via Orphanet 34 H51.8
UMLS via Orphanet 73 C0543874
Orphanet 59 ORPHA1125
MedGen 42 C0543874
UMLS 72 C0009421 C3489733

Summaries for Ocular Motor Apraxia

NIH Rare Diseases : 53 Oculomotor apraxia Cogan type (COMA) is an eye condition characterized by a defect in side-to-side (horizontal) eye movements. Because of this, most patients with COMA have to turn their head in order to follow objects in side gaze. Typically, up-to-down (vertical) eye movements are unaffected. Symptoms usually improve throughout the childhood and teenage years. COMA can also be associated with mild developmental delay and speech difficulties. Individuals with COMA may also have kidney disorders and underdevelopment of the part of cerebellum that separates the left and right hemisphere of the brain (cerebellar vermis). When other symptoms occur, COMA may be a symptom of other disorders, such as nephronophthisis or Joubert syndrome. In many instances, the cause of COMA is not known; however, researchers suspect that it is inherited in an autosomal recessive inheritance pattern. Treatment for this condition is focused on managing the signs and symptoms in each individual.

MalaCards based summary : Ocular Motor Apraxia, also known as coma, is related to apraxia and hypoglycemic coma, and has symptoms including seizures, tremor and back pain. An important gene associated with Ocular Motor Apraxia is COMA (Cogan-Type Congential Oculomotor Apraxia). The drugs Clavulanate and Dobutamine have been mentioned in the context of this disorder. Affiliated tissues include brain, liver and eye, and related phenotypes are nephronophthisis and oculomotor apraxia

OMIM : 57 Congenital oculomotor apraxia, first reported by Cogan (1952), is characterized by (1) defective or absent horizontal voluntary eye movements, and (2) defective or absent horizontal ocular attraction movements. Oculomotor apraxia occurs in ataxia-telangiectasia (208900). Also see ataxia-oculomotor apraxia syndrome (208920; 606002). Oculomotor apraxia has been observed in the neuronopathic form of Gaucher disease (type III; 231000) (Erikson and Wahlberg, 1985; Gross-Tsur et al., 1989). (257550)

MedlinePlus : 43 A coma is a deep state of unconsciousness. An individual in a coma is alive but unable to move or respond to his or her environment. Coma may occur as a complication of an underlying illness, or as a result of injuries, such as brain injury. A coma rarely lasts more than 2 to 4 weeks. The outcome for coma depends on the cause, severity, and site of the damage. People may come out of a coma with physical, intellectual, and psychological problems. Some people may remain in a coma for years or even decades. For those people, the most common cause of death is infection, such as pneumonia. NIH: National Institute of Neurological Disorders and Stroke

NINDS : 54 A coma, sometimes also called persistent vegetative state, is a profound or deep state of unconsciousness. Persistent vegetative state is not brain-death. An individual in a state of coma is alive but unable to move or respond to his or her environment. Coma may occur as a complication of an underlying illness, or as a result of injuries, such as head trauma. Individuals in such a state have lost their thinking abilities and awareness of their surroundings, but retain non-cognitive function and normal sleep patterns. Even though those in a persistent vegetative state lose their higher brain functions, other key functions such as breathing and circulation remain relatively intact. Spontaneous movements may occur, and the eyes may open in response to external stimuli. Individuals may even occasionally grimace, cry, or laugh. Although individuals in a persistent vegetative state may appear somewhat normal, they do not speak and they are unable to respond to commands.

Related Diseases for Ocular Motor Apraxia

Diseases related to Ocular Motor Apraxia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 869)
# Related Disease Score Top Affiliating Genes
1 apraxia 30.2 NPHP1 APTX
2 hypoglycemic coma 12.7
3 hepatic coma 12.5
4 basedow's coma 12.4
5 ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia 11.8
6 viral hepatitis 11.8
7 joubert syndrome 1 11.7
8 akinetic mutism 11.6
9 hepatic encephalopathy 11.5
10 persistent vegetative state 11.5
11 creutzfeldt-jakob disease 11.5
12 familial hemiplegic migraine 11.5
13 ornithine transcarbamylase deficiency, hyperammonemia due to 11.5
14 lysinuric protein intolerance 11.5
15 acyl-coa dehydrogenase, medium-chain, deficiency of 11.5
16 wernicke-korsakoff syndrome 11.4
17 japanese encephalitis 11.4
18 central pontine myelinolysis 11.4
19 citrullinemia, classic 11.4
20 carbamoyl phosphate synthetase i deficiency, hyperammonemia due to 11.4
21 hyperinsulinemic hypoglycemia, familial, 2 11.4
22 cerebral beriberi 11.4
23 carnitine deficiency, systemic primary 11.4
24 propionic acidemia 11.4
25 acute disseminated encephalomyelitis 11.4
26 metabolic acidosis 11.3
27 anoxia 11.3
28 brain edema 11.3
29 malaria 11.3
30 eclampsia 11.3
31 hemiplegic migraine 11.3
32 reye syndrome 11.3
33 insulinoma 11.3
34 hypoxia 11.3
35 hypophosphatemia 11.3
36 cerebral hypoxia 11.3
37 n-acetylglutamate synthase deficiency 11.3
38 maple syrup urine disease 11.3
39 diabetes mellitus, insulin-dependent 11.3
40 urea cycle disorder 11.2
41 migraine, familial hemiplegic, 1 11.2
42 pre-eclampsia 11.2
43 alcohol use disorder 11.2
44 carnitine palmitoyltransferase i deficiency 11.2
45 adrenoleukodystrophy 11.2
46 autoimmune encephalitis 11.2
47 migraine, familial hemiplegic, 2 11.2
48 sleeping sickness 11.2
49 st. louis encephalitis 11.2
50 marchiafava bignami disease 11.2

Comorbidity relations with Ocular Motor Apraxia via Phenotypic Disease Network (PDN): (show all 16)


Active Peptic Ulcer Disease Acute Cystitis
Acute Kidney Failure Alzheimer Disease
Cardiac Arrest Decubitus Ulcer
Deficiency Anemia Epilepsy, Focal, with Speech Disorder and with or Without Mental Retardation
Familial Atrial Fibrillation Heart Disease
Hypertension, Essential Protein-Energy Malnutrition
Respiratory Failure Schizophreniform Disorder
Swallowing Disorders Ventricular Fibrillation, Paroxysmal Familial, 1

Graphical network of the top 20 diseases related to Ocular Motor Apraxia:



Diseases related to Ocular Motor Apraxia

Symptoms & Phenotypes for Ocular Motor Apraxia

Human phenotypes related to Ocular Motor Apraxia:

32
# Description HPO Frequency HPO Source Accession
1 nephronophthisis 32 HP:0000090
2 oculomotor apraxia 32 HP:0000657
3 jerky head movements 32 HP:0006961
4 horizontal opticokinetic nystagmus 32 HP:0008026

Symptoms via clinical synopsis from OMIM:

57
Head And Neck Head:
jerking head movements

Head And Neck Eyes:
oculomotor apraxia (defective/absent horizontal eye movements)

Neurologic Central Nervous System:
jerking head movements

Clinical features from OMIM:

257550

UMLS symptoms related to Ocular Motor Apraxia:


seizures, tremor, back pain, ophthalmoparesis, pain, headache, lethargy, syncope, excessive daytime somnolence, chronic pain, sciatica, vertigo/dizziness, sleeplessness, symptoms, central nervous system signs and symptoms, clouded consciousness, sluggishness, dizziness, transient alteration of awareness, other alteration of consciousness

Drugs & Therapeutics for Ocular Motor Apraxia

Drugs for Ocular Motor Apraxia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 409)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
2
Dobutamine Approved Phase 4 34368-04-2 36811
3
Clopidogrel Approved Phase 4 113665-84-2, 120202-66-6 60606
4
Haloperidol Approved Phase 4 52-86-8 3559
5
Histamine Approved, Investigational Phase 4 51-45-6 774
6
Esomeprazole Approved, Investigational Phase 4 119141-88-7, 161796-78-7, 161973-10-0 9568614 4594
7
Famotidine Approved Phase 4 76824-35-6 3325
8
Zinc Approved, Investigational Phase 4 7440-66-6 32051
9
Insulin glargine Approved Phase 4 160337-95-1
10
Gliclazide Approved Phase 4 21187-98-4 3475
11
Abciximab Approved Phase 4 143653-53-6
12
Tirofiban Approved Phase 4 144494-65-5 60947
13
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
14
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
15
Diethylcarbamazine Approved, Investigational, Vet_approved Phase 4 90-89-1 3052
16
Ivermectin Approved, Investigational, Vet_approved Phase 4 70288-86-7 6474909
17
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
18
Lactulose Approved Phase 4 4618-18-2 11333
19
Rifaximin Approved, Investigational Phase 4 80621-81-4 46783403 6436173
20
Ferrous fumarate Approved Phase 4 141-01-5
21
Iron Approved, Experimental Phase 4 15438-31-0, 7439-89-6 23925 27284
22
Ticagrelor Approved Phase 4 274693-27-5 9871419
23
Cangrelor Approved Phase 4 163706-06-7 9854012
24
Prednisone Approved, Vet_approved Phase 4 53-03-2 5865
25
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
26
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
27
tannic acid Approved Phase 4 1401-55-4
28
Benzocaine Approved, Investigational Phase 4 94-09-7, 1994-09-7 2337
29
Acetaminophen Approved Phase 4 103-90-2 1983
30
Conivaptan Approved, Investigational Phase 4 210101-16-9 151171
31
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3
32
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
33
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
34
Tolvaptan Approved Phase 4 150683-30-0 216237
35
Ornithine Approved, Nutraceutical Phase 4 70-26-8, 3184-13-2 6262
36
Folic acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
37
Thiamine Approved, Investigational, Nutraceutical, Vet_approved Phase 4 59-43-8, 70-16-6 1130
38
Aspartic acid Approved, Nutraceutical Phase 4 56-84-8 5960
39 phenylalanine Phase 4
40 Amoxicillin-Potassium Clavulanate Combination Phase 4
41 Antipsychotic Agents Phase 4
42 Anesthetics, Inhalation Phase 4
43 Haloperidol decanoate Phase 4
44 Dopamine Antagonists Phase 4
45 Chlorhexidine gluconate Phase 4
46 glutamine Phase 4
47 alanine Phase 4
48 Folate Phase 4
49 Vitamin B9 Phase 4
50 Vitamin B Complex Phase 4

Interventional clinical trials:

(show top 50) (show all 616)
# Name Status NCT ID Phase Drugs
1 Treatment of Intracranial Hypertension of Severe Tramatic Brain Injured Patients. Physiopathologic Effects of Neuromuscular Blocking Agents. A Controlled Randomized Study Versus Placebo Unknown status NCT02404779 Phase 4 cisatracurium besilate
2 Pilot Randomized Clinical Trial Comparing the Efficacy of Two Different Hypothermia Temperatures for Treatment of Comatose Patients Recovered From an Out-of-hospital Cardiac Arrest Completed NCT01155622 Phase 4
3 Prophylactic Versus Clinically-driven Antibiotics in Comatose Survivors of Out-of-hospital Cardiac Arrest Completed NCT02899507 Phase 4 Amoxicillin-Clavulanic acid
4 Wavefront Analisys and Contrast Sensitivity of Spherical and Aspherical Completed NCT00347243 Phase 4
5 Comparison of Antiplatelet Therapy With Clopidogrel and Ticagrelor in Patients After Cardiac Arrest Treated With Therapeutic Hypothermia Completed NCT02224274 Phase 4 Clopidogrel;Ticagrelor
6 Preventing ICU Subsyndromal Delirium Conversion to Delirium With Low Dose IV Haloperidol: A Double-Blind, Placebo-Controlled Pilot Study Completed NCT01174290 Phase 4 Haloperidol decanoate;Placebo
7 Improvement of Therapy in Patients With Severe Traumatic Brain Injury: Differential Impact of Local and Systemic Changes and Routinely Applied Drugs Completed NCT02130674 Phase 4 Dipeptiven
8 Thiamin Deficiency in Obese Thai Children Completed NCT02464865 Phase 4 Thiamine 1;Thiamine 2
9 Comparison of Esomeprazole and Famotidine for Stress Ulcer Prophylaxis in Neurosurgical Intensive Care Unit Completed NCT00633035 Phase 4 esomeprazole 40 mg;famotidine 20 mg
10 Phase 4 Prospective, Randomized, Blinded Study on the Effect of Different Hydration Strategies on Mortality and Changes in Quality of Life of Patients Suffering From Subarachnoid Haemorrhage Completed NCT02064075 Phase 4 Lactated Ringer's solution;Hydroxyethyl starch
11 Weaning With Smartcare in Mechanically Ventilated Patients in the ICU - a Controlled and Randomized Study Completed NCT02122016 Phase 4
12 Phase 4 Study of Comparison of Combination Therapy of Gliclazide MR and Basal Insulin With Pre-mix Insulin Monotherapy for the Patients With Type 2 Diabetes Mellitus Completed NCT00736515 Phase 4 Gliclazide MR and Insulin Glargine Injection;Biosynthetic Human Insulin Injection
13 LOLA in Hepatic Encephalopathy Brain Muscle Axis During Treatment of Hepatic Encephalopathy With L-ornithine L-aspartate A Phase iv Randomised Double Blind Placebo- Controlled Trial Completed NCT01847651 Phase 4 LOLA or placebo
14 FATA: Comparison Between Tirofiban and Abciximab in Facilitated Angioplasty With Stent Implantation: Randomized Multicentre Study Completed NCT00383136 Phase 4 tirofiban high-bolus dose regimen;Abciximab
15 Effect of Oral Decontamination Using Chlorhexidine or Potassium Permanganate in ICU Patients: an Open-Labelled Randomized Controlled Trial Completed NCT00610324 Phase 4 Chlorhexidine gluconate;Potassium permanganate
16 Multicenter, Randomised Study of the Use of Non-Invasive Ventilation (NIV) Versus Oxygen Therapy (O2) in Reducing Dyspnea in End-stage Solid Cancer Patients With Respiratory Failure and Distress Completed NCT00533143 Phase 4
17 Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin on Post-operative Opioid Use and Patient Satisfaction Completed NCT01977937 Phase 4 Gabapentin 250mg/5mL NDC:59762-5025-01;Simple Syrup
18 Comparison of Total Intravenous Anesthesia vs. Inhalational Anesthesia on Brain Relaxation, Subdural Pressure and Hemodynamics in Patients With Acute Subdural Hematoma Undergoing Emergency Craniotomy- A Randomized Control Trial Completed NCT03146104 Phase 4 Propofol;Isoflurane
19 Strategy of Early Improvement of Tissue Oxygenation Decrease the Mortality of Severe Sepsis Completed NCT01310790 Phase 4
20 Comparison Between the Post-Treatment Reactions After Single-dose Ivermectin or DEC in Subjects With Loa Loa Infection Completed NCT01593722 Phase 4 Diethylcarbamazine;Ivermectin
21 Introduction of New Hypo-Osmolar ORS (Recommended by WHO) for Routine Use in the Management of Diarrhoeal Diseases – A Phase IV Surveillance Study Completed NCT00490932 Phase 4 Hypo-osmolar ORS
22 Spherical Aberration and Contrast Sensitivity in Eyes Implanted With Aspheric and Spherical Intraocular Lenses: Clinical Comparative Study Completed NCT00576485 Phase 4
23 Phase 4 Study of a Reminiscence Program to Improve Quality of Life of Alzheimer's Disease Long Term Care Residents Using a Randomized Controlled Trial Completed NCT01295957 Phase 4
24 Efficacy of Intravenous 'L-ornithine L-aspartate' in Reversal of Overt Acute Hepatic Encephalopathy in Patients With Liver Cirrhosis: a Prospective, Randomized, Double-blind, Placebo Controlled Trial Completed NCT01722578 Phase 4 L-ornithine L-aspartate;Placebo
25 PROcalcitonin Pneumonia / Pneumonitis Associated With ASPIration Recruiting NCT02862314 Phase 4
26 Dexmedetomidine to Reduce the Incidence of Persistent Cognitive Dysfunction After Open Cardiac Surgery: A Pilot Randomized Trial Recruiting NCT03480061 Phase 4 Dexmedetomidine Hydrochloride Group
27 Pharmacokinetic/Pharmacodynamic Effects of add-on Antiplatelet Therapy With Parenteral Cangrelor as Compared to Standard Dual Antiplatelet Treatment in Patients With ST-elevation Myocardial Infarction Complicated by Out-of-hospital Cardiac Arrest and Treated With Targeted Temperature Management Recruiting NCT03273075 Phase 4 Cangrelor;Placebo;Prasugrel;Ticagrelor
28 The Effect of Ramelteon on Delirium and Sleep in Patients Admitted to the ICU Recruiting NCT03931070 Phase 4 Ramelteon;Placebo - Cap
29 Therapeutic Efficacy of Oral PEG3350 Plus Lactulose Versus Lactulose Alone in Patients of Acute on Chronic Liver Failure With Overt Hepatic Encephalopathy: A Single Blind Prospective Randomized Controlled Study Recruiting NCT03987893 Phase 4 PEG-3350 with Electolytes;Lactulose
30 Preoperative, Single-dose Intravenous Iron Formulation to Reduce Post-surgical Complications in Patients Undergoing Major Abdominal Surgery: a Pilot Randomised Control Trial (PIRCAS Trial - Pilot) Recruiting NCT03295851 Phase 4 Ferric carboxymaltose;Ferrous Fumarate
31 Platelet Inhibition With Cangrelor in Comatose Survivors of Out-of-hospital Cardiac Arrest Undergoing Primary Percutaneous Coronary Intervention Not yet recruiting NCT04005729 Phase 4 Cangrelor 50 MG
32 The Applicability of Different Scoring Systems and Use of Steroids in the Treatment of Hospital Acquired Pneumonia Not yet recruiting NCT03121690 Phase 4 Prednisone;placebo
33 Mild Induced Hypothermia to Treat Severe Community Acquired Meningitis in Adults Admitted to Intensive Care Unit Terminated NCT00774631 Phase 4
34 Use of Conivaptan (Vaprisol) for Hyponatremic Neuro-ICU Patients Terminated NCT00727090 Phase 4 Conivaptan
35 Role of Dexamethasone in the Conservative Treatment of Chronic Subdural Hematoma: a Double-blind Randomized Controlled Pilot Study Terminated NCT02362321 Phase 4 Dexamethasone
36 A Multi-Center Trial to Study Acute Liver Failure: N-Acetylcysteine (NAC) Open Label Use Study Terminated NCT00896025 Phase 4 N-acetylcysteine
37 Propofol Versus Midazolam for Sedation in Mechanically Ventilated Critically Ill Patients Who Presented With Traumatic Brain Injury: Cytokine Response and Neuropsychological Assessment (IRRC#1201M) Terminated NCT01712477 Phase 4 Intravenous sedation using propofol;Intravenous sedation with midazolam
38 Clinical, Pharmacological and Molecular Effects of Intravenous and Oral Acetaminophen in Adults With Aneurysmal Sub-Arachnoid Hemorrhage Terminated NCT02549716 Phase 4 IV acetaminophen;Oral acetaminophen;Oral placebo;IV placebo
39 Tight Intra-Operative Glucose Control Using Continuous Insulin Infusion During Coronary Artery Bypass Surgery: Randomized Controlled Trial Terminated NCT00394303 Phase 4 Intraoperative continuous insulin infusion
40 Tolvaptan to Reduce Length of Stay in Hospitalized Patients With Cirrhosis and Hyponatremia Terminated NCT01890694 Phase 4 Tolvaptan;Placebo
41 Antibiotic Prophylaxis for Early Ventilator-associated Pneumonia in Neurological Patients: A Randomized Trial Withdrawn NCT01118403 Phase 4 Sultamicillin
42 The Efficacy and Safety of Cleviprex in Ventriculostomy Patients Requiring IV Antihypertensive Therapy Investigator Initiated Trial Withdrawn NCT01042574 Phase 4 Clevidipine butyrate
43 Inhaled Nebulised S(+)-Ketamine for Postoperative Analgesia Withdrawn NCT02397356 Phase 4 Ketamine first AB;Placebo first BA
44 Asia Coma Electrical Stimulation Trial: an Asian Multicenter Randomized Controlled Trial to Assess the Efficacy and Safety of Right Median Nerve Stimulation for Traumatic Coma Unknown status NCT02645578 Phase 3
45 Effect of Mannitol as Adjunct Therapy on the Clinical Outcome of Childhood Cerebral Malaria in Mulago Hospital: A Randomised Clinical Trial Unknown status NCT00113854 Phase 3 Mannitol
46 RICE Trial: Rifaximin In Chronic Hepatic Encephalopathy - A Randomized, Controlled Trial Unknown status NCT00364689 Phase 3 Rifaximin alone, Rifaximin combined with Lactulose
47 Pilot Study of Hypothermia for Intracerebral Hemorrhage in Croatia Unknown status NCT01221142 Phase 3
48 Vagus Nerve Stimulation to Augment Recovery From Minimally Conscious or Persistently Vegetative States After Traumatic Brain Injury Unknown status NCT01260090 Phase 3
49 NEWBORN VENTILATION IN THE DELIVERY ROOM: CAN IT BE IMPROVED WITH A LARYNGEAL MASK AIRWAY? A Prospective, Randomized Single-center Study Unknown status NCT01963936 Phase 3
50 Randomized Trial of Erythropoietin to Prevent Death From Cerebral Impairment During Severe Malaria Unknown status NCT00697164 Phase 2, Phase 3 Placebo;Erythropoietin

Search NIH Clinical Center for Ocular Motor Apraxia

Genetic Tests for Ocular Motor Apraxia

Anatomical Context for Ocular Motor Apraxia

MalaCards organs/tissues related to Ocular Motor Apraxia:

41
Brain, Liver, Eye, Testes, Kidney, Heart, Thyroid

Publications for Ocular Motor Apraxia

Articles related to Ocular Motor Apraxia:

(show top 50) (show all 30160)
# Title Authors PMID Year
1
Children with ocular motor apraxia type Cogan carry deletions in the gene (NPHP1) for juvenile nephronophthisis. 38 8
10839884 2000
2
Familial congenital saccade initiation failure and isolated cerebellar vermis hypoplasia. 38 8
9881808 1998
3
Gaucher disease--Norrbottnian type. Ocular abnormalities. 38 8
4003050 1985
4
Familial congenital ocular motor apraxia and immune deficiency. 38 8
7387458 1980
5
Congenital ocular motor apraxia. A possible disconnection syndrome. 38 8
420600 1979
6
Congenital ocular motor apraxia. 38 8
589433 1977
7
Cogan's congenital ocular motor apraxia in two successive generations. 38 8
4643438 1972
8
Heredity of congenital ocular motor apraxia. 38 8
5024601 1972
9
Congenital ocular motor apraxia in identical twins. 38 8
5937501 1966
10
A type of congenital ocular motor apraxia presenting jerky head movements. 38 8
13005548 1952
11
Oculomotor apraxia: the presenting sign of Gaucher disease. 8
2712947 1989
12
[Cogan's congenital oculomotor apraxia. Apropos of 3 recent cases, 2 of them in the same sibship]. 8
6060428 1967
13
Proposed safe apnea test using positive end-expiratory pressure valve and short-term blood gas analysis: Observational study. 17
31083250 2019
14
Machine perfusion versus cold storage in renal preservation of deceased donors with brain death: systematic review and meta-analysis. 17
31090864 2019
15
Brain stem death - an overview. 17
30785835 2019
16
Changes on Dynamic Cerebral Autoregulation Are Associated with Delayed Cerebral Ischemia in Patients with Aneurysmal Subarachnoid Hemorrhage. 38
31407076 2020
17
Unhelmeted Motorcycle Riders Have Increased Injury Burden: A Need to Revisit Universal Helmet Laws. 38
31078903 2019
18
The malaria toxin hemozoin induces apoptosis in human neurons and astrocytes: Potential role in the pathogenesis of cerebral malaria. 38
31276637 2019
19
Differences in 90-day mortality of delirium subtypes in the intensive care unit: A retrospective cohort study. 38
31228762 2019
20
Early Imaging Associated With Improved Survival in Older Patients With Mild Traumatic Brain Injuries. 38
31059948 2019
21
Length of Stay and ICU Stay Are Increased With Repair of Traumatic Superior Mesenteric Vein Injury. 38
31071610 2019
22
Frequency of and Risk Factors for Chronification in Traumatic Acute Subdural Hematoma following Conservative Therapy. 38
31181579 2019
23
Prevalence and Risk Factors of Exposure Keratopathy Across Different Intensive Care Units. 38
31394552 2019
24
Higher plasma C-type lectin-like receptor 2 concentrations for prediction of higher risk of 30-day mortality in isolated severe blunt traumatic brain injury. 38
31202718 2019
25
Pneumonia in acute ischemic stroke patients requiring invasive ventilation: Impact on short and long-term outcomes. 38
31238051 2019
26
Prediction of functional outcome and discharge destination in patients with traumatic brain injury after post-acute rehabilitation. 38
31033582 2019
27
Multi-centre study found that strict adherence to guidelines led to computed tomography scans being overused in children with minor head injuries. 38
30721540 2019
28
Minimally Invasive Surgery for Spontaneous Cerebellar Hemorrhage: A Multicenter Study. 38
31042595 2019
29
Decompressive Craniectomy in Children with Severe Traumatic Brain Injury: A Multicenter Retrospective Study and Literature Review. 38
31054345 2019
30
Poor prognostic factors in elderly patients aged 75 years old or older with mild traumatic brain injury. 38
31221574 2019
31
Prediction of Best-Corrected Visual Acuity With Swept-Source Optical Coherence Tomography Parameters in Keratoconus. 38
31394554 2019
32
Time in Collars and Collar-Related Complications in Older Patients. 38
31150857 2019
33
Outcome of Craniocerebral Penetrating Injuries: Experience from the Syrian War. 38
31051521 2019
34
Decompressive craniectomy for severe traumatic brain injury in children: analysis of long-term neuropsychological impairment and review of the literature. 38
31264065 2019
35
Continuous Versus Bolus Infusion of Hypertonic Saline in the Treatment of Symptomatic Hyponatremia Caused by SIAD. 38
30882872 2019
36
Risk factors of hospital mortality in chronic subdural hematoma: A retrospective analysis of 1117 patients, a single institute experience. 38
31213382 2019
37
Prehospital information and spot sign are complementary predictors of post-admission outcomes of intracerebral hematoma. 38
31221577 2019
38
Clinical significance of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in acute cerebral hemorrhage with gastrointestinal hemorrhage, and logistic regression analysis of risk factors. 38
31410106 2019
39
The EMCOOLs surface cooling system for fever control in neurocritical care patients: A pilot study. 38
31323544 2019
40
Late recovery of responsiveness after intra-thecal baclofen pump implantation and the role of diffuse pain and severe spasticity: a case report. 38
31267188 2019
41
Prehospital Versus Trauma Center Glasgow Coma Scale in Pediatric Traumatic Brain Injury Patients. 38
31022676 2019
42
Severe quetiapine voluntary overdose successfully treated with a new hemoperfusion sorbent. 38
31006356 2019
43
Acute hemorrhagic leukoencephalitis of Weston Hurst secondary to herpes encephalitis presenting as status epilepticus: A case report and review of literature. 38
31239199 2019
44
Neuropathology of Spontaneous Hypertensive Encephalopathy in Cats. 38
31113291 2019
45
Massive eucalyptus oil overdose leading to prolonged coma. 38
30806522 2019
46
Prognostic factors for adult patients with hemorrhagic moyamoya disease in the acute stage. 38
31302379 2019
47
Sex-Specific Differences in Clinical Characteristics and Outcomes Among Patients with Vascular Abnormality-Related Intracerebral Hemorrhage. 38
31181362 2019
48
Haemodynamics as a determinant of need for pre-hospital application of a pelvic circumferential compression device in adult trauma patients. 38
31431329 2019
49
Genetic variants of the oppA gene are involved in metabolic regulation of surfactin in Bacillus subtilis. 38
31426791 2019
50
Outcome following postneurosurgical Acinetobacter meningitis: an institutional experience of 72 cases. 38
31370029 2019

Variations for Ocular Motor Apraxia

Copy number variations for Ocular Motor Apraxia from CNVD:

7
# CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 134868 2 108600000 113800000 Copy number Ocular motor apraxia

Expression for Ocular Motor Apraxia

Search GEO for disease gene expression data for Ocular Motor Apraxia.

Pathways for Ocular Motor Apraxia

GO Terms for Ocular Motor Apraxia

Sources for Ocular Motor Apraxia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
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