MCID: ODN005
MIFTS: 32

Odontogenic Myxoma

Categories: Rare diseases

Aliases & Classifications for Odontogenic Myxoma

MalaCards integrated aliases for Odontogenic Myxoma:

Name: Odontogenic Myxoma 52 71

Classifications:



External Ids:

UMLS 71 C0334569

Summaries for Odontogenic Myxoma

MalaCards based summary : Odontogenic Myxoma is related to ameloblastoma and gingival overgrowth. An important gene associated with Odontogenic Myxoma is CD36 (CD36 Molecule), and among its related pathways/superpathways are Innate Immune System and Integrin Pathway. Affiliated tissues include bone, heart and smooth muscle, and related phenotypes are homeostasis/metabolism and integument

Wikipedia : 74 The odontogenic myxoma is an uncommon benign odontogenic tumor arising from embryonic connective tissue... more...

Related Diseases for Odontogenic Myxoma

Diseases related to Odontogenic Myxoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 208)
# Related Disease Score Top Affiliating Genes
1 ameloblastoma 30.2 SERPINA3 MMP9 MMP2
2 gingival overgrowth 30.0 MMP2 MMP1 DCN CD36
3 neurofibroma 29.8 VIM VEGFA S100B
4 osteogenic sarcoma 29.7 MMP9 MMP2 IGF1R DCN
5 fibrous histiocytoma 29.7 VIM SERPINA3 S100B
6 granular cell tumor 29.7 VIM SERPINA3 S100B
7 malignant fibrous histiocytoma 29.6 VIM SERPINA3 S100B
8 tuberous sclerosis 29.3 VIM VEGFA S100B
9 villonodular synovitis 10.5 VIM MMP9
10 interstitial keratitis 10.4 DCN CD36
11 chronic actinic dermatitis 10.4 MMP9 MMP1
12 extracranial arteriovenous malformation 10.4 MMP9 MMP2
13 focal myositis 10.4 MMP9 MMP2
14 acute transverse myelitis 10.4 MMP9 MMP2
15 transverse myelitis 10.4 MMP9 MMP2
16 nasal cavity squamous cell carcinoma 10.4 MMP9 MMP2
17 vaginal endometrial stromal sarcoma 10.3 VIM IGF1R
18 root resorption 10.3
19 senile ectropion 10.3 MMP9 MMP2
20 pediatric multiple sclerosis 10.3 ORM1 MMP9
21 vagina sarcoma 10.3 VIM IGF1R
22 hydromyelia 10.3 VIM S100B
23 hypertrophic scars 10.3 MMP2 CD36
24 bednar tumor 10.3 VIM S100B
25 primary hepatic neuroendocrine carcinoma 10.3 VIM S100B
26 rare tumor 10.3
27 scleredema adultorum 10.3 MMP1 DCN
28 angiocentric glioma 10.3 VIM S100B
29 tendinosis 10.3 MMP1 DCN
30 cutaneous leiomyosarcoma 10.2 VIM S100B
31 angiokeratoma circumscriptum 10.2 VEGFA MMP9
32 anaplastic ependymoma 10.2 VIM S100B
33 eccrine porocarcinoma 10.2 VIM S100B
34 sick building syndrome 10.2 VEGFA MMP9
35 parotitis 10.2 MMP9 MMP2
36 chordoid meningioma 10.2 VIM S100B
37 brittle bone disorder 10.2 DCN CD36 ACAN
38 traumatic brain injury 10.2 S100B MMP9
39 ossifying fibromyxoid tumor 10.2 VIM S100B
40 polymorphous low-grade adenocarcinoma 10.2 VIM S100B
41 fibroma 10.2
42 tooth resorption 10.2
43 collagenous colitis 10.2 MMP9 MMP1 COL14A1
44 congenital epulis 10.2 VIM SERPINA3
45 epulis 10.2 VIM SERPINA3
46 tuberculous meningitis 10.2 VEGFA MMP9
47 ovarian mucinous cystadenocarcinoma 10.2 VIM SERPINA3
48 dendritic cell tumor 10.2 VIM S100B
49 multicentric reticulohistiocytosis 10.2 VIM SERPINA3
50 lipodermatosclerosis 10.2 VEGFA MMP1

Graphical network of the top 20 diseases related to Odontogenic Myxoma:



Diseases related to Odontogenic Myxoma

Symptoms & Phenotypes for Odontogenic Myxoma

MGI Mouse Phenotypes related to Odontogenic Myxoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.11 CD36 DCN IGF1R MMP1 MMP2 MMP9
2 integument MP:0010771 9.87 COL14A1 DCN IGF1R MMP9 S100B SERPINA3
3 muscle MP:0005369 9.86 CD36 COL14A1 DCN IGF1R MMP2 MMP9
4 neoplasm MP:0002006 9.63 DCN IGF1R MMP1 MMP2 MMP9 VEGFA
5 respiratory system MP:0005388 9.43 DCN IGF1R MMP2 MMP9 VEGFA VIM
6 skeleton MP:0005390 9.23 CD36 COL14A1 DCN IGF1R MMP2 MMP9

Drugs & Therapeutics for Odontogenic Myxoma

Search Clinical Trials , NIH Clinical Center for Odontogenic Myxoma

Genetic Tests for Odontogenic Myxoma

Anatomical Context for Odontogenic Myxoma

MalaCards organs/tissues related to Odontogenic Myxoma:

40
Bone, Heart, Smooth Muscle, Skin

Publications for Odontogenic Myxoma

Articles related to Odontogenic Myxoma:

(show top 50) (show all 322)
# Title Authors PMID Year
1
First insights for targeted therapies in odontogenic myxoma. 61
31713744 2020
2
Odontogenic Myxoma: A 23-Year Retrospective Series of 38 Cases. 61
32506377 2020
3
Reconstruction of Mandibular Defects With Bone Marrow-Derived Stem Cells in Odontogenic Myxoma. 61
31977681 2020
4
Corrigendum to "Recurrence rate of odontogenic myxoma after different treatments: a systematic review" [Br J Oral Maxillofac Surg 57 (December 10) (2019) 985-991]. 61
32061381 2020
5
Odontogenic Myxoma: Systematic review and bias analysis. 61
32048275 2020
6
Odontogenic myxomas lack PDGFRB mutations reported in myofibromas. 61
32050038 2020
7
Odontogenic myxoma of posterior maxilla - A rare case report. 61
32509683 2020
8
The Rare Radiographic Sunburst Appearance of Odontogenic Myxomas: A Case Report and Review of the Literature. 61
31902092 2020
9
Recurrence rate of odontogenic myxoma after different treatments: a systematic review. 61
31551163 2019
10
Disfiguring Giant Odontogenic Myxoma of Mandible: A Case Report with Brief Review of Literature. 61
31741930 2019
11
Primordial odontogenic tumor with prominent calcifications: A rare case report. 61
31636866 2019
12
Odontogenic myxoma: An updated analysis of 1,692 cases reported in the literature. 61
29683236 2019
13
Bringing benign ectomesenchymal odontogenic tumours to the lab: An in vitro study using an organotypic culture model. 61
30554445 2019
14
Odontogenic tumors and lesions treated in a single specialist oral and maxillofacial pathology unit in the United Kingdom in 1992-2016. 61
30448231 2019
15
Odontogenic myxoma in an 8-year-old girl: A case report with review of literature. 61
30967732 2019
16
Long-Term Follow-Up after Conservative Surgical Treatment of Odontogenic Myxoma: A Case Report and Literature Review. 61
30886752 2019
17
Appropriate surgical margin for odontogenic myxoma: a review of 12 cases. 61
30093315 2018
18
Odontogenic tumours in Nigeria: A multicentre study of 582 cases and review of the literature. 61
30341260 2018
19
Clinicopathological analysis of odontogenic tumors over 22 years period: Experience of a single center in northeastern Brazil. 61
30341267 2018
20
Clinical and Histopathological Analysis of Odontogenic Tumors in Institution-A 10 Years Retrospective Study. 61
30498188 2018
21
Treatment For The Large Aggressive Benign Lesions Of The Jaws. 61
30034157 2018
22
Odontogenic tumors: A 35-year retrospective study of 250 cases in an Indian (Maharashtra) teaching institute. 61
30693892 2018
23
Odontogenic myxoma in a child treated with enucleation and curettage. 61
30237989 2018
24
Management of primary odontogenic myxoma. 61
29879802 2018
25
Evaluation of the osteoclastogenic process associated with RANK / RANK-L / OPG in odontogenic myxomas. 61
29680857 2018
26
An atypical odontogenic myxoma. 61
29229314 2018
27
Size distribution and clinicoradiological signs of aggressiveness in odontogenic myxoma-three-dimensional analysis and systematic review. 61
29082773 2018
28
Evaluation and Immunolocalization of BMP4 and FGF8 in Odontogenic Cyst and Tumors. 61
30079292 2018
29
Maxillofacial Radiographic study of Gardner's syndrome presenting with odontogenic myxoma: A rare case report. 61
30531170 2018
30
Odontogenic myxoma: A causality dilemma - Report of a nonpareil case and review of literature. 61
29491595 2018
31
Odontogenic myxoma: A 63-year retrospective multicenter study of 85 cases in a Brazil population and a review of 999 cases from literature. 61
28985009 2018
32
Myxofibroma of the maxilla, current concepts, and differential diagnosis. 61
30895084 2017
33
Surgical Access to a Complex Composite Odontoma via Sagittal Split Osteotomy of the Mandible. 61
29441249 2017
34
Next-generation sequencing of oncogenes and tumor suppressor genes in odontogenic myxomas. 61
28597929 2017
35
Epidemiological and Clinicopathological Analysis of 92 Odontogenic Tumors: A 5-year Retrospective Study. 61
29109321 2017
36
Pattern of distribution of odontogenic tumours in sub-Saharan Africa. 61
28485021 2017
37
Odontogenic myxoma: A review with report of an uncommon case with recurrence in the mandible of a teenage male. 61
28725126 2017
38
Peripheral odontogenic myxoma in a 12-year-old girl: a rare entity. 61
28770159 2017
39
Endoscopic resection of the pterygoid plates following incomplete transoral resection of an odontogenic myxoma. 61
27576161 2017
40
Epidemiological study of odontogenic tumours: An institutional experience. 61
27425795 2017
41
Clinicopathologic analysis of 14 cases of odontogenic myxoma and review of the literature. 61
28469823 2017
42
[Odontogenic myxoma of the maxilla: report of a case]. 61
30240557 2017
43
Extra-Osseous Odontogenic Myxoma of Maxillary Gingiva. 61
28302237 2017
44
Odontogenic myxoma of the maxilla: surgical management and case report. 61
26975322 2017
45
Characteristic features of the odontogenic myxoma on cone beam computed tomography. 61
27936914 2017
46
Long-term clinical and radiologic documentation of a maxillary odontogenic myxoma from early clinical signs to implant-supported prosthodontic rehabilitation: Case report and review of the literature. 61
28439572 2017
47
A comparative study of syndecan-1 expression in different odontogenic tumors. 61
28316917 2017
48
Odontogenic myxoma in the paediatric patient: a review of eight cases. 61
27515849 2016
49
Management of Recurrent Odontogenic Myxoma of Mandible: A Clinical Case Report. 61
27891488 2016
50
Odontogenic myxoma with diffuse calcifications: a case report and review of a rare histologic feature. 61
26948020 2016

Variations for Odontogenic Myxoma

Expression for Odontogenic Myxoma

Search GEO for disease gene expression data for Odontogenic Myxoma.

Pathways for Odontogenic Myxoma

Pathways related to Odontogenic Myxoma according to GeneCards Suite gene sharing:

(show all 31)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.86 VIM VEGFA SERPINA3 S100B ORM1 MMP9
2
Show member pathways
13.24 VEGFA VCAN MMP9 MMP2 MMP1 COL14A1
3
Show member pathways
13.2 VIM VEGFA MMP9 MMP2 MMP1 CD36
4 12.69 VEGFA MMP9 MMP2 MMP1 IGF1R
5
Show member pathways
12.52 VEGFA MMP9 MMP2 MMP1
6
Show member pathways
12.35 VCAN MMP9 MMP2 MMP1 DCN COL14A1
7 12.14 VEGFA MMP9 MMP2 IGF1R DCN
8 12.07 VEGFA MMP9 MMP2 MMP1
9
Show member pathways
11.98 VCAN DCN ACAN
10 11.95 VEGFA MMP9 MMP2
11 11.9 VIM VCAN MMP9 ACAN
12
Show member pathways
11.78 MMP9 MMP2 MMP1
13 11.75 VCAN DCN ACAN
14 11.67 VCAN MMP9 MMP2
15 11.66 VIM VEGFA S100B
16 11.62 VEGFA MMP9 MMP2 MMP1
17 11.52 VEGFA MMP9 IGF1R ACAN
18 11.49 VCAN DCN ACAN
19
Show member pathways
11.47 VEGFA MMP9 MMP2 MMP1
20 11.22 MMP9 MMP2 CD36
21 11.21 VCAN MMP9 MMP1 ACAN
22 11.16 VIM VEGFA MMP9 MMP2 MMP1 CD36
23 11.14 VCAN MMP9 MMP2 MMP1 IGF1R
24 11.1 MMP9 MMP2 IGF1R
25 11.09 MMP9 MMP2 MMP1 DCN
26 11.03 VEGFA MMP9
27 11.01 MMP9 MMP2
28 10.96 MMP2 MMP1
29 10.93 VEGFA SERPINA3 MMP1
30 10.88 VIM VCAN IGF1R COL14A1 ACAN
31 10.85 MMP9 MMP1

GO Terms for Odontogenic Myxoma

Cellular components related to Odontogenic Myxoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.96 VEGFA VCAN SERPINA3 S100B ORM1 MMP9
2 extracellular region GO:0005576 9.9 VEGFA VCAN SERPINA3 S100B ORM1 MMP9
3 Golgi lumen GO:0005796 9.58 VCAN DCN ACAN
4 collagen-containing extracellular matrix GO:0062023 9.56 VCAN SERPINA3 ORM1 MMP9 MMP2 DCN
5 lysosomal lumen GO:0043202 9.54 VCAN DCN ACAN
6 platelet alpha granule lumen GO:0031093 9.5 VEGFA SERPINA3 ORM1
7 extracellular matrix GO:0031012 9.23 VEGFA VCAN MMP9 MMP2 MMP1 DCN

Biological processes related to Odontogenic Myxoma according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 skeletal system development GO:0001501 9.69 VCAN MMP9 ACAN
2 central nervous system development GO:0007417 9.65 VCAN S100B ACAN
3 positive regulation of cold-induced thermogenesis GO:0120162 9.54 VEGFA IGF1R CD36
4 extracellular matrix disassembly GO:0022617 9.5 MMP9 MMP2 MMP1
5 macrophage differentiation GO:0030225 9.49 VEGFA MMP9
6 response to amyloid-beta GO:1904645 9.46 MMP9 MMP2
7 platelet degranulation GO:0002576 9.46 VEGFA SERPINA3 ORM1 CD36
8 chondroitin sulfate catabolic process GO:0030207 9.43 VCAN DCN
9 collagen catabolic process GO:0030574 9.43 MMP9 MMP2 MMP1
10 cytokine-mediated signaling pathway GO:0019221 9.43 VIM VEGFA MMP9 MMP2 MMP1 CD36
11 dermatan sulfate biosynthetic process GO:0030208 9.4 VCAN DCN
12 extracellular matrix organization GO:0030198 9.17 VCAN MMP9 MMP2 MMP1 DCN COL14A1

Molecular functions related to Odontogenic Myxoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metalloendopeptidase activity GO:0004222 9.43 MMP9 MMP2 MMP1
2 endopeptidase activity GO:0004175 9.33 MMP9 MMP2 MMP1
3 collagen binding GO:0005518 9.13 MMP9 DCN COL14A1
4 extracellular matrix structural constituent conferring compression resistance GO:0030021 8.8 VCAN DCN ACAN

Sources for Odontogenic Myxoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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