MCID: ODN005
MIFTS: 31

Odontogenic Myxoma

Categories: Rare diseases

Aliases & Classifications for Odontogenic Myxoma

MalaCards integrated aliases for Odontogenic Myxoma:

Name: Odontogenic Myxoma 20 70

Classifications:



External Ids:

UMLS 70 C0334569

Summaries for Odontogenic Myxoma

MalaCards based summary : Odontogenic Myxoma is related to gingival overgrowth and ameloblastoma. An important gene associated with Odontogenic Myxoma is CD36 (CD36 Molecule), and among its related pathways/superpathways are Innate Immune System and Integrin Pathway. Affiliated tissues include bone marrow and smooth muscle, and related phenotypes are homeostasis/metabolism and muscle

Wikipedia : 73 The odontogenic myxoma is an uncommon benign odontogenic tumor arising from embryonic connective tissue... more...

Related Diseases for Odontogenic Myxoma

Diseases related to Odontogenic Myxoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 213)
# Related Disease Score Top Affiliating Genes
1 gingival overgrowth 30.1 MMP2 MMP1 DCN CD36
2 ameloblastoma 29.9 SERPINA3 MMP9 MMP2
3 neurofibroma 29.8 VIM VEGFA S100B
4 fibrous histiocytoma 29.8 VIM SERPINA3 S100B
5 granular cell tumor 29.7 VIM SERPINA3 S100B
6 malignant fibrous histiocytoma 29.7 VIM SERPINA3 S100B
7 osteogenic sarcoma 29.7 MMP9 MMP2 IGF1R DCN
8 tuberous sclerosis 29.6 VIM VEGFA S100B
9 basal cell carcinoma 29.5 VEGFA MMP9 MMP2 MMP1
10 interstitial keratitis 10.3 DCN CD36
11 vaginal endometrial stromal sarcoma 10.3 VIM IGF1R
12 epicondylitis 10.3 DCN ACAN
13 vagina sarcoma 10.3 VIM IGF1R
14 scleredema adultorum 10.3 MMP1 DCN
15 hypertrophic scars 10.3 MMP2 CD36
16 chronic actinic dermatitis 10.2 MMP9 MMP1
17 hydromyelia 10.2 VIM S100B
18 bednar tumor 10.2 VIM S100B
19 extracranial arteriovenous malformation 10.2 MMP9 MMP2
20 focal myositis 10.2 MMP9 MMP2
21 primary hepatic neuroendocrine carcinoma 10.2 VIM S100B
22 rare tumor 10.2
23 tendinosis 10.2 MMP1 DCN
24 acute transverse myelitis 10.2 MMP9 MMP2
25 angiocentric glioma 10.2 VIM S100B
26 villonodular synovitis 10.2 MMP9 MMP1
27 nasal cavity squamous cell carcinoma 10.2 MMP9 MMP2
28 cutaneous leiomyosarcoma 10.2 VIM S100B
29 senile ectropion 10.2 MMP9 MMP2
30 nasal cavity benign neoplasm 10.2 MMP9 MMP2
31 chordoid meningioma 10.2 VIM S100B
32 anaplastic ependymoma 10.2 VIM S100B
33 ossifying fibromyxoid tumor 10.2 VIM S100B
34 polymorphous low-grade adenocarcinoma 10.2 VIM S100B
35 eccrine porocarcinoma 10.2 VIM S100B
36 fibroma 10.2
37 tooth resorption 10.2
38 root resorption 10.2
39 dendritic cell tumor 10.2 VIM S100B
40 congenital epulis 10.2 VIM SERPINA3
41 epulis 10.2 VIM SERPINA3
42 fibrous meningioma 10.2 VIM S100B
43 spiradenoma 10.2 VIM S100B
44 lipodermatosclerosis 10.2 VEGFA MMP1
45 optic nerve glioma 10.2 VIM S100B
46 multicentric reticulohistiocytosis 10.2 VIM SERPINA3
47 ovarian mucinous cystadenocarcinoma 10.2 VIM SERPINA3
48 parotitis 10.2 MMP9 MMP2
49 pediatric multiple sclerosis 10.2 ORM1 MMP9
50 fibromatosis, gingival, 1 10.2 MMP2 MMP1 CD36

Graphical network of the top 20 diseases related to Odontogenic Myxoma:



Diseases related to Odontogenic Myxoma

Symptoms & Phenotypes for Odontogenic Myxoma

MGI Mouse Phenotypes related to Odontogenic Myxoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.03 CD36 COL14A1 DCN IGF1R MMP1 MMP2
2 muscle MP:0005369 9.76 CD36 COL14A1 DCN IGF1R MMP2 MMP9
3 neoplasm MP:0002006 9.43 DCN IGF1R MMP1 MMP2 MMP9 VEGFA
4 skeleton MP:0005390 9.23 CD36 COL14A1 DCN IGF1R MMP2 MMP9

Drugs & Therapeutics for Odontogenic Myxoma

Search Clinical Trials , NIH Clinical Center for Odontogenic Myxoma

Genetic Tests for Odontogenic Myxoma

Anatomical Context for Odontogenic Myxoma

MalaCards organs/tissues related to Odontogenic Myxoma:

40
Bone Marrow, Smooth Muscle

Publications for Odontogenic Myxoma

Articles related to Odontogenic Myxoma:

(show top 50) (show all 331)
# Title Authors PMID Year
1
Transfacial transmandibular approach to the masticator space: Excision of odontogenic myxoma arising from the mandibular condyle. 61
33592553 2021
2
Odontogenic Myxoma: A 23-Year Retrospective Series of 38 Cases. 61
32506377 2020
3
The Rare Radiographic Sunburst Appearance of Odontogenic Myxomas: A Case Report and Review of the Literature. 61
31902092 2020
4
Expression of stem cell markers in stroma of odontogenic cysts and tumors. 61
32840915 2020
5
New World Health Organization classification of odontogenic tumours: impact on the prevalence of odontogenic tumours and analysis of 1231 cases from Turkey. 61
32684315 2020
6
Challenges With the Jaw in a Day Technique. 61
32707040 2020
7
Mandibular odontogenic myxoma in a paediatric patient. 61
33127701 2020
8
Odontogenic myxoma: ambiguous pathology of anterior maxilla. 61
32843449 2020
9
First insights for targeted therapies in odontogenic myxoma. 61
31713744 2020
10
Hybrid Odontogenic Tumor of Calcifying Odontogenic Cyst and Ameloblastic Fibroma: a Case Report and Review of Literature. 61
32582832 2020
11
Reconstruction of Mandibular Defects With Bone Marrow-Derived Stem Cells in Odontogenic Myxoma. 61
31977681 2020
12
Corrigendum to "Recurrence rate of odontogenic myxoma after different treatments: a systematic review" [Br J Oral Maxillofac Surg 57 (December 10) (2019) 985-991]. 61
32061381 2020
13
Odontogenic Myxoma: Systematic review and bias analysis. 61
32048275 2020
14
Intramandibular plexiform schwannoma presenting as a nonspecific benign lesion: How specific can we be? A case report with a review of the literature. 61
32719282 2020
15
Odontogenic myxomas lack PDGFRB mutations reported in myofibromas. 61
32050038 2020
16
Odontogenic myxoma of posterior maxilla - A rare case report. 61
32509683 2020
17
Multidisciplinary Approach to Rehabilitation after Tumor Resective Jaw Surgery: A 9-Year Follow-Up. 61
33381326 2020
18
Recurrence rate of odontogenic myxoma after different treatments: a systematic review. 61
31551163 2019
19
Disfiguring Giant Odontogenic Myxoma of Mandible: A Case Report with Brief Review of Literature. 61
31741930 2019
20
Primordial odontogenic tumor with prominent calcifications: A rare case report. 61
31636866 2019
21
Odontogenic myxoma: An updated analysis of 1,692 cases reported in the literature. 61
29683236 2019
22
Odontogenic myxoma in an 8-year-old girl: A case report with review of literature. 61
30967732 2019
23
Bringing benign ectomesenchymal odontogenic tumours to the lab: An in vitro study using an organotypic culture model. 61
30554445 2019
24
Odontogenic tumors and lesions treated in a single specialist oral and maxillofacial pathology unit in the United Kingdom in 1992-2016. 61
30448231 2019
25
Long-Term Follow-Up after Conservative Surgical Treatment of Odontogenic Myxoma: A Case Report and Literature Review. 61
30886752 2019
26
Appropriate surgical margin for odontogenic myxoma: a review of 12 cases. 61
30093315 2018
27
Odontogenic tumours in Nigeria: A multicentre study of 582 cases and review of the literature. 61
30341260 2018
28
Clinicopathological analysis of odontogenic tumors over 22 years period: Experience of a single center in northeastern Brazil. 61
30341267 2018
29
Clinical and Histopathological Analysis of Odontogenic Tumors in Institution-A 10 Years Retrospective Study. 61
30498188 2018
30
Treatment For The Large Aggressive Benign Lesions Of The Jaws. 61
30034157 2018
31
Odontogenic tumors: A 35-year retrospective study of 250 cases in an Indian (Maharashtra) teaching institute. 61
30693892 2018
32
Odontogenic myxoma in a child treated with enucleation and curettage. 61
30237989 2018
33
Management of primary odontogenic myxoma. 61
29879802 2018
34
Evaluation of the osteoclastogenic process associated with RANK / RANK-L / OPG in odontogenic myxomas. 61
29680857 2018
35
An atypical odontogenic myxoma. 61
29229314 2018
36
Size distribution and clinicoradiological signs of aggressiveness in odontogenic myxoma-three-dimensional analysis and systematic review. 61
29082773 2018
37
Odontogenic myxoma: A 63-year retrospective multicenter study of 85 cases in a Brazil population and a review of 999 cases from literature. 61
28985009 2018
38
Odontogenic myxoma: A causality dilemma - Report of a nonpareil case and review of literature. 61
29491595 2018
39
Evaluation and Immunolocalization of BMP4 and FGF8 in Odontogenic Cyst and Tumors. 61
30079292 2018
40
Maxillofacial Radiographic study of Gardner's syndrome presenting with odontogenic myxoma: A rare case report. 61
30531170 2018
41
Myxofibroma of the maxilla, current concepts, and differential diagnosis. 61
30895084 2017
42
Surgical Access to a Complex Composite Odontoma via Sagittal Split Osteotomy of the Mandible. 61
29441249 2017
43
Next-generation sequencing of oncogenes and tumor suppressor genes in odontogenic myxomas. 61
28597929 2017
44
Epidemiological and Clinicopathological Analysis of 92 Odontogenic Tumors: A 5-year Retrospective Study. 61
29109321 2017
45
Pattern of distribution of odontogenic tumours in sub-Saharan Africa. 61
28485021 2017
46
Odontogenic myxoma: A review with report of an uncommon case with recurrence in the mandible of a teenage male. 61
28725126 2017
47
Peripheral odontogenic myxoma in a 12-year-old girl: a rare entity. 61
28770159 2017
48
Epidemiological study of odontogenic tumours: An institutional experience. 61
27425795 2017
49
Endoscopic resection of the pterygoid plates following incomplete transoral resection of an odontogenic myxoma. 61
27576161 2017
50
Clinicopathologic analysis of 14 cases of odontogenic myxoma and review of the literature. 61
28469823 2017

Variations for Odontogenic Myxoma

Expression for Odontogenic Myxoma

Search GEO for disease gene expression data for Odontogenic Myxoma.

Pathways for Odontogenic Myxoma

Pathways related to Odontogenic Myxoma according to GeneCards Suite gene sharing:

(show all 31)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.86 VIM VEGFA SERPINA3 S100B ORM1 MMP9
2
Show member pathways
13.24 VEGFA VCAN MMP9 MMP2 MMP1 COL14A1
3
Show member pathways
13.2 VIM VEGFA MMP9 MMP2 MMP1 CD36
4 12.69 VEGFA MMP9 MMP2 MMP1 IGF1R
5
Show member pathways
12.52 VEGFA MMP9 MMP2 MMP1
6
Show member pathways
12.35 VCAN MMP9 MMP2 MMP1 DCN COL14A1
7 12.14 VEGFA MMP9 MMP2 IGF1R DCN
8 12.07 VEGFA MMP9 MMP2 MMP1
9
Show member pathways
11.98 VCAN DCN ACAN
10 11.95 VEGFA MMP9 MMP2
11 11.9 VIM VCAN MMP9 ACAN
12
Show member pathways
11.78 MMP9 MMP2 MMP1
13 11.75 VCAN DCN ACAN
14 11.67 VCAN MMP9 MMP2
15 11.66 VIM VEGFA S100B
16 11.62 VEGFA MMP9 MMP2 MMP1
17 11.52 VEGFA MMP9 IGF1R ACAN
18 11.49 VCAN DCN ACAN
19
Show member pathways
11.47 VEGFA MMP9 MMP2 MMP1
20 11.22 MMP9 MMP2 CD36
21 11.21 VCAN MMP9 MMP1 ACAN
22 11.16 VIM VEGFA MMP9 MMP2 MMP1 CD36
23 11.14 VCAN MMP9 MMP2 MMP1 IGF1R
24 11.1 MMP9 MMP2 IGF1R
25 11.09 MMP9 MMP2 MMP1 DCN
26 11.03 VEGFA MMP9
27 11.01 MMP9 MMP2
28 10.96 MMP2 MMP1
29 10.93 VEGFA SERPINA3 MMP1
30 10.88 VIM VCAN IGF1R COL14A1 ACAN
31 10.85 MMP9 MMP1

GO Terms for Odontogenic Myxoma

Cellular components related to Odontogenic Myxoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.96 VEGFA VCAN SERPINA3 S100B ORM1 MMP9
2 extracellular region GO:0005576 9.9 VEGFA VCAN SERPINA3 S100B ORM1 MMP9
3 Golgi lumen GO:0005796 9.58 VCAN DCN ACAN
4 collagen-containing extracellular matrix GO:0062023 9.56 VCAN SERPINA3 ORM1 MMP9 MMP2 DCN
5 lysosomal lumen GO:0043202 9.54 VCAN DCN ACAN
6 platelet alpha granule lumen GO:0031093 9.5 VEGFA SERPINA3 ORM1
7 extracellular matrix GO:0031012 9.23 VEGFA VCAN MMP9 MMP2 MMP1 DCN

Biological processes related to Odontogenic Myxoma according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 central nervous system development GO:0007417 9.71 VCAN S100B ACAN
2 skeletal system development GO:0001501 9.7 VCAN MMP9 ACAN
3 positive regulation of MAPK cascade GO:0043410 9.69 VEGFA IGF1R CD36
4 positive regulation of cold-induced thermogenesis GO:0120162 9.61 VEGFA IGF1R CD36
5 positive regulation of phosphatidylinositol 3-kinase signaling GO:0014068 9.58 VEGFA IGF1R DCN
6 platelet degranulation GO:0002576 9.56 VEGFA SERPINA3 ORM1 CD36
7 macrophage differentiation GO:0030225 9.55 VEGFA MMP9
8 extracellular matrix disassembly GO:0022617 9.54 MMP9 MMP2 MMP1
9 collagen catabolic process GO:0030574 9.5 MMP9 MMP2 MMP1
10 response to amyloid-beta GO:1904645 9.49 MMP9 MMP2
11 chondroitin sulfate catabolic process GO:0030207 9.48 VCAN DCN
12 dermatan sulfate biosynthetic process GO:0030208 9.46 VCAN DCN
13 cytokine-mediated signaling pathway GO:0019221 9.43 VIM VEGFA MMP9 MMP2 MMP1 CD36
14 cellular response to UV-A GO:0071492 9.33 MMP9 MMP2 MMP1
15 extracellular matrix organization GO:0030198 9.17 VCAN MMP9 MMP2 MMP1 DCN COL14A1

Molecular functions related to Odontogenic Myxoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metalloendopeptidase activity GO:0004222 9.43 MMP9 MMP2 MMP1
2 endopeptidase activity GO:0004175 9.33 MMP9 MMP2 MMP1
3 collagen binding GO:0005518 9.13 MMP9 DCN COL14A1
4 extracellular matrix structural constituent conferring compression resistance GO:0030021 8.8 VCAN DCN ACAN

Sources for Odontogenic Myxoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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