Aliases & Classifications for Odontoma

MalaCards integrated aliases for Odontoma:

Name: Odontoma 53 29 55 73

Classifications:



External Ids:

UMLS 73 C0028882

Summaries for Odontoma

MalaCards based summary : Odontoma is related to ameloblastoma and odontoma-dysphagia syndrome. An important gene associated with Odontoma is LHX8 (LIM Homeobox 8), and among its related pathways/superpathways are Keratinization and Cytoskeletal Signaling. Affiliated tissues include bone and testes, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Wikipedia : 76 An odontoma (also termed odontome) is a benign tumour of odontogenic origin (i.e. linked to tooth... more...

Related Diseases for Odontoma

Diseases related to Odontoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 120)
# Related Disease Score Top Affiliating Genes
1 ameloblastoma 29.8 KRT14 KRT18 KRT8 PCNA
2 odontoma-dysphagia syndrome 12.4
3 encephalocraniocutaneous lipomatosis 11.2
4 calcifying epithelial odontogenic tumor 10.9
5 dens evaginatus 10.9
6 brooke-spiegler syndrome 10.7 KRT14 KRT8
7 epidermolysis bullosa simplex, autosomal recessive 1 10.7 KRT14 KRT5
8 benign breast adenomyoepithelioma 10.7 KRT14 KRT5
9 epidermolysis bullosa simplex, localized 10.7 KRT14 KRT5
10 lichen planopilaris 10.7 KRT14 KRT5
11 large cell acanthoma 10.7 KRT14 KRT5
12 epidermolysis bullosa simplex, generalized 10.7 KRT14 KRT5
13 epidermolysis bullosa simplex with mottled pigmentation 10.7 KRT14 KRT5
14 breast squamous cell carcinoma 10.7 KRT14 KRT5
15 basaloid squamous cell carcinoma 10.6 KRT14 KRT8
16 atypical choroid plexus papilloma 10.6 KRT5 KRT8
17 breast adenomyoepithelioma 10.6 KRT14 KRT5
18 breast myoepithelial neoplasm 10.6 KRT14 KRT5
19 epidermolysis bullosa simplex, dowling-meara type 10.6 KRT14 KRT5
20 prostate squamous cell carcinoma 10.6 KRT5 KRT8
21 nasal cavity squamous cell carcinoma 10.6 KRT5 KRT8
22 vesiculobullous skin disease 10.6 KRT14 KRT5
23 breast secretory carcinoma 10.6 KRT5 KRT8
24 ameloblastic carcinoma 10.6 KRT14 VIM
25 leukoplakia 10.6 KRT8 PCNA
26 pleomorphic liposarcoma 10.6 KRT8 VIM
27 lipid-rich carcinoma 10.6 KRT14 KRT5
28 lymphangiomatosis 10.6 PCNA VIM
29 spiradenoma 10.6 KRT14 VIM
30 ovarian mucinous cystadenocarcinoma 10.6 PCNA VIM
31 peritoneum cancer 10.6 KRT5 TUBB3
32 long-chain 3-hydroxyacyl-coa dehydrogenase deficiency 10.5 KRT8 VIM
33 papillary adenoma 10.5 KRT5 VIM
34 mucinous cystadenocarcinoma 10.5 PCNA VIM
35 pre-malignant neoplasm 10.5 KRT14 KRT5
36 neurenteric cyst 10.4 KRT18 KRT8
37 secretory meningioma 10.4 KRT8 VIM
38 chondroid chordoma 10.4 TUBB3 VIM
39 hidradenocarcinoma 10.4 KRT5 VIM
40 cryptogenic cirrhosis 10.4 KRT18 KRT8
41 pleomorphic carcinoma 10.4 KRT18 KRT8
42 apocrine sweat gland neoplasm 10.4 KRT14 KRT5 KRT8
43 sweat gland cancer 10.4 KRT14 KRT5 KRT8
44 benign mesothelioma 10.4 KRT5 VIM
45 ductal carcinoma in situ 10.3 KRT14 KRT5 KRT8
46 ependymoblastoma 10.3 NES VIM
47 astroblastoma 10.3 NES VIM
48 medulloepithelioma 10.3 NES VIM
49 optic nerve neoplasm 10.3 KRT5 NES
50 in situ carcinoma 10.3 KRT14 KRT5

Graphical network of the top 20 diseases related to Odontoma:



Diseases related to Odontoma

Symptoms & Phenotypes for Odontoma

GenomeRNAi Phenotypes related to Odontoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.47 KRT5
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-154 9.47 KRT18
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-17 9.47 KRT18 KRT5
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.47 KRT5 KRT8
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.47 KRT5
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.47 KRT18
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-40 9.47 KRT8
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.47 KRT18 KRT5 KRT8
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.47 KRT18
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.47 KRT5

MGI Mouse Phenotypes related to Odontoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.35 KRT14 KRT19 KRT5 KRT8 LHX8
2 mortality/aging MP:0010768 9.28 KRT14 KRT18 KRT19 KRT5 KRT8 LHX8

Drugs & Therapeutics for Odontoma

Search Clinical Trials , NIH Clinical Center for Odontoma

Genetic Tests for Odontoma

Genetic tests related to Odontoma:

# Genetic test Affiliating Genes
1 Odontoma 29

Anatomical Context for Odontoma

MalaCards organs/tissues related to Odontoma:

41
Bone, Testes

Publications for Odontoma

Articles related to Odontoma:

(show top 50) (show all 534)
# Title Authors Year
1
A Bag of Marbles: A Fascinating Compound Odontoma of the Maxilla. ( 29663916 )
2018
2
Rare case of bilateral complex odontoma associated with mandibular bicuspids. ( 29922342 )
2018
3
Gingival complex odontoma: a rare case report with a review of the literature. ( 29515984 )
2018
4
Ameloblastic fibro-odontoma with chondroid tissue formation. ( 29692665 )
2018
5
An unusual foreign object mimicking an odontoma in a patient with cleft alveolus: a case report. ( 28946895 )
2017
6
Immediate Dental Implant Placement After Removal of Complex Odontoma. ( 28922246 )
2017
7
Association Between Odontoma and Impacted Teeth. ( 28106699 )
2017
8
Ameloblastic Fibro-Odontoma of the Maxilla in a Pierre-Robin Sequence Patient. ( 28557592 )
2017
9
Association Between Odontoma and Impacted Teeth. ( 28468159 )
2017
10
Compound Odontoma in Anterior Mandible-A Case Report. ( 28814937 )
2017
11
Giant Complex Odontoma of Mandible: A Spectacular Case Report. ( 28839489 )
2017
12
A rare case report of an adenomatoid odontogenic tumor associated with odontoma in the maxilla. ( 28863377 )
2017
13
Spontaneous Peripheral Ameloblastic Odontoma in a Male Sprague-Dawley Rat. ( 28503263 )
2017
14
Ameloblastic Fibro-Odontoma in a 7-Month-Old Infant: A Case Report. ( 29034280 )
2017
15
Ameloblastic Fibro-odontoma with a Predominant Radiopaque Component. ( 29264304 )
2017
16
Ameloblastic Fibrodentinoma and Ameloblastic Fibro-Odontoma: An Updated Systematic Review of Cases Reported in the Literature. ( 28153756 )
2017
17
Autotransplantation of Odontoma-Associated Impacted Teeth-A Treatment Strategy for Satisfying Immediate Esthetic Demands: A Case Report. ( 28460214 )
2017
18
Surgical Access to a Complex Composite Odontoma via Sagittal Split Osteotomy of the Mandible. ( 29441249 )
2017
19
Clinical, pathological, and genetic evaluations of Chinese patient with otodental syndrome and multiple complex odontoma: Case report. ( 28151902 )
2017
20
Removal of Compound Odontoma With Piezosurgery Technique. ( 28278140 )
2017
21
Peripheral osteoma, compound odontoma, focal cemento-osseous dysplasia, and cemento-ossifying fibroma in the same hemimandible: CBCT findings of an unusual case. ( 29484064 )
2017
22
Metachronous ameloblastic fibro-odontoma and dentigerous cyst in the posterior mandible. ( 29099370 )
2017
23
Dilated odontoma: A report of two cases from a radiological perspective. ( 27041914 )
2016
24
Long-term culture of human odontoma-derived cells with a Rho kinase inhibitor. ( 27514999 )
2016
25
Lateral Approach for Excision of Maxillary Incisor Pseudo-Odontoma in Prairie Dogs (Cynomys ludovicianus). ( 26709130 )
2016
26
Diagnostic Discussion. Ameloblastic fibro-odontoma. ( 27024969 )
2016
27
Peripheral Developing Odontoma or Peripheral Ameloblastic Fibroodontoma: A Rare Challenging Case. ( 26981293 )
2016
28
Erupted Large Anterior Maxillary Complex Odontoma: A Rare Dental Hamartoma. ( 27790601 )
2016
29
Dentigerous cyst arising from a complex odontoma: an unusual presentation. ( 27090549 )
2016
30
Compound composite odontoma. ( 27194882 )
2016
31
Management of a massive compound odontoma in a 9-year child. ( 27630512 )
2016
32
An Erupted Dilated Odontoma: A Rare Presentation. ( 26989523 )
2016
33
Peripheral Tumor with Osteodentin and Cementum-like Material in an Infant: Odontogenic Hamartoma or Odontoma? ( 27098720 )
2016
34
Diverse calcification patterns of ameloblastic fibro-odontoma on radiographic examination. ( 28025437 )
2016
35
Campylorrhinus lateralis, Bilateral microphthalmia and odontoma temporalis in an Oldenburg Foal. ( 26825866 )
2016
36
Large ameloblastic fibro-odontoma in a 7-year-old girl with analysis of 108 cases. ( 27563600 )
2016
37
Odontoma in a 255-Million-Year-Old Mammalian Forebear. ( 27930769 )
2016
38
Ameloblastic fibroodontoma or complex odontoma: Two faces of the same coin. ( 28163488 )
2016
39
Extensive Mandibular Ameloblastic Fibro-Odontoma. ( 27428924 )
2016
40
Multiple complex odontoma of the maxilla and mandible-reply. ( 26972543 )
2016
41
Management of a Compound Odontoma in the Primary Dentition. ( 27620522 )
2016
42
Response to the Letter Entitled &amp;quot;Archegonous Cystic Odontoma Is Not Necessarily Primordial&amp;quot; by Ide et al. ( 26857026 )
2016
43
Archegonous Cystic Odontoma Is Not Necessarily Primordial. ( 26843411 )
2016
44
Compound odontoma associated with impacted maxillary central incisor dictates a need to be vigilant to canine eruption pattern: A 2-year follow-up. ( 27307685 )
2016
45
Complex Odontoma: A Case Report with Micro-Computed Tomography Findings. ( 27293913 )
2016
46
Ameloblastic Fibro-Odontoma in a 4-Year-Old Boy. ( 27307963 )
2016
47
Ectopic compound odontoma in the buccal mucosa: report of a rare case. ( 25810930 )
2015
48
Primordial Odontogenic Cyst with Induction Phenomenon (Zonal Fibroblastic Hypercellularity) and Dentinoid Material Versus Archegonous Cystic Odontoma: You Choose! ( 26156422 )
2015
49
Super odontoma - a destructive swarm entity. ( 25954721 )
2015
50
Surgical Management of Compound Odontoma Associated with Unerupted Tooth. ( 26199762 )
2015

Variations for Odontoma

Expression for Odontoma

Search GEO for disease gene expression data for Odontoma.

Pathways for Odontoma

GO Terms for Odontoma

Cellular components related to Odontoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.86 KRT14 KRT18 KRT19 KRT5 KRT8 PCNA
2 keratin filament GO:0045095 9.46 KRT14 KRT18 KRT5 KRT8
3 apicolateral plasma membrane GO:0016327 9.4 KRT19 KRT8
4 costamere GO:0043034 9.37 KRT19 KRT8
5 dystrophin-associated glycoprotein complex GO:0016010 9.32 KRT19 KRT8
6 cell periphery GO:0071944 9.26 KRT18 KRT19 KRT8 TUBB3
7 intermediate filament GO:0005882 9.17 KRT14 KRT18 KRT19 KRT5 KRT8 NES

Biological processes related to Odontoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 viral process GO:0016032 9.67 KRT18 KRT19 KRT8 VIM
2 extrinsic apoptotic signaling pathway GO:0097191 9.43 KRT18 KRT8
3 sarcomere organization GO:0045214 9.4 KRT19 KRT8
4 keratinization GO:0031424 9.35 KRT14 KRT18 KRT19 KRT5 KRT8
5 hemidesmosome assembly GO:0031581 9.32 KRT14 KRT5
6 hepatocyte apoptotic process GO:0097284 9.26 KRT18 KRT8
7 cell differentiation involved in embryonic placenta development GO:0060706 9.16 KRT19 KRT8
8 cornification GO:0070268 9.02 KRT14 KRT18 KRT19 KRT5 KRT8

Molecular functions related to Odontoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 9.56 KRT18 KRT8 NES VIM
2 scaffold protein binding GO:0097110 9.26 KRT18 KRT5 KRT8 VIM
3 keratin filament binding GO:1990254 9.16 KRT14 VIM
4 structural constituent of cytoskeleton GO:0005200 9.02 KRT14 KRT19 KRT5 TUBB3 VIM

Sources for Odontoma

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7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
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32 HPO
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34 ICD10 via Orphanet
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62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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