Aliases & Classifications for Odontoma

MalaCards integrated aliases for Odontoma:

Name: Odontoma 54 30 56 74

Classifications:



External Ids:

UMLS 74 C0028882

Summaries for Odontoma

MalaCards based summary : Odontoma is related to ameloblastoma and odontoma-dysphagia syndrome. An important gene associated with Odontoma is LHX8 (LIM Homeobox 8), and among its related pathways/superpathways are Keratinization and Cytoskeletal Signaling. Affiliated tissues include bone and testes, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Wikipedia : 77 An odontoma is a benign tumour linked to tooth development. Specifically, it is a dental hamartoma,... more...

Related Diseases for Odontoma

Diseases related to Odontoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 120)
# Related Disease Score Top Affiliating Genes
1 ameloblastoma 30.4 KRT14 KRT18 KRT8 PCNA
2 odontoma-dysphagia syndrome 12.6
3 encephalocraniocutaneous lipomatosis 11.4
4 calcifying epithelial odontogenic tumor 11.1
5 fibroma 10.4
6 brooke-spiegler syndrome 10.4 KRT14 KRT8
7 neurenteric cyst 10.3 KRT18 KRT8
8 benign breast adenomyoepithelioma 10.3 KRT14 KRT5
9 breast adenomyoepithelioma 10.3 KRT14 KRT5
10 lichen planopilaris 10.3 KRT14 KRT5
11 epidermolysis bullosa simplex, autosomal recessive 1 10.3 KRT14 KRT5
12 large cell acanthoma 10.3 KRT14 KRT5
13 epidermolysis bullosa simplex, localized 10.3 KRT14 KRT5
14 epidermolysis bullosa simplex, generalized 10.3 KRT14 KRT5
15 breast squamous cell carcinoma 10.3 KRT14 KRT5
16 cryptogenic cirrhosis 10.3 KRT18 KRT8
17 epidermolysis bullosa simplex with mottled pigmentation 10.3 KRT14 KRT5
18 breast myoepithelial neoplasm 10.3 KRT14 KRT5
19 vesiculobullous skin disease 10.3 KRT14 KRT5
20 basaloid squamous cell carcinoma 10.3 KRT14 KRT8
21 breast benign neoplasm 10.3 KRT14 KRT5
22 prostate squamous cell carcinoma 10.3 KRT5 KRT8
23 thoracic benign neoplasm 10.3 KRT14 KRT5
24 lymphoepithelioma-like thymic carcinoma 10.3 KRT18 KRT5
25 schneiderian carcinoma 10.3 KRT18 KRT5
26 nasal cavity squamous cell carcinoma 10.3 KRT5 KRT8
27 epidermolysis bullosa simplex, dowling-meara type 10.3 KRT14 KRT5
28 atypical choroid plexus papilloma 10.3 KRT5 KRT8
29 lipid-rich carcinoma 10.3 KRT14 KRT5
30 breast secretory carcinoma 10.3 KRT5 KRT8
31 teeth, supernumerary 10.3
32 sweat gland disease 10.3 KRT14 KRT5
33 sarcomatoid squamous cell skin carcinoma 10.3 KRT5 KRT8
34 tonsil cancer 10.3 KRT14 KRT5
35 pre-malignant neoplasm 10.3 KRT14 KRT5
36 nephrogenic adenofibroma 10.2 KRT18 KRT8
37 sinusitis 10.2
38 pineal gland cancer 10.2 KRT18 TUBB3
39 oropharynx cancer 10.2 KRT14 KRT5
40 optic nerve neoplasm 10.2 KRT5 NES
41 leukoplakia 10.2 KRT8 PCNA
42 ameloblastic carcinoma 10.2 KRT14 VIM
43 adenoid squamous cell carcinoma 10.2 KRT8 VIM
44 breast fibroadenoma 10.2 KRT14 KRT8
45 apocrine sweat gland neoplasm 10.2 KRT14 KRT5 KRT8
46 maxillary sinusitis 10.2
47 pleomorphic liposarcoma 10.2 KRT8 VIM
48 in situ carcinoma 10.2 KRT14 KRT5
49 ductal carcinoma in situ 10.2 KRT14 KRT5 KRT8
50 long-chain 3-hydroxyacyl-coa dehydrogenase deficiency 10.2 KRT8 VIM

Graphical network of the top 20 diseases related to Odontoma:



Diseases related to Odontoma

Symptoms & Phenotypes for Odontoma

GenomeRNAi Phenotypes related to Odontoma according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.47 KRT5
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-154 9.47 KRT18
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-17 9.47 KRT18 KRT5
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.47 KRT5 KRT8
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.47 KRT5
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.47 KRT18
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-40 9.47 KRT8
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.47 KRT18 KRT5 KRT8
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.47 KRT18
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.47 KRT5

MGI Mouse Phenotypes related to Odontoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.35 KRT14 KRT19 KRT5 KRT8 LHX8
2 mortality/aging MP:0010768 9.28 KRT14 KRT18 KRT19 KRT5 KRT8 LHX8

Drugs & Therapeutics for Odontoma

Search Clinical Trials , NIH Clinical Center for Odontoma

Genetic Tests for Odontoma

Genetic tests related to Odontoma:

# Genetic test Affiliating Genes
1 Odontoma 30

Anatomical Context for Odontoma

MalaCards organs/tissues related to Odontoma:

42
Bone, Testes

Publications for Odontoma

Articles related to Odontoma:

(show top 50) (show all 547)
# Title Authors Year
1
Incidentally detected odontoma within a dentigerous cyst. ( 30840819 )
2019
2
A Bag of Marbles: A Fascinating Compound Odontoma of the Maxilla. ( 29663916 )
2018
3
Rare case of bilateral complex odontoma associated with mandibular bicuspids. ( 29922342 )
2018
4
Gingival complex odontoma: a rare case report with a review of the literature. ( 29515984 )
2018
5
Ameloblastic fibro-odontoma with chondroid tissue formation. ( 29692665 )
2018
6
Mixed odontogenic tumors in four young dogs: ameloblastic fibroma and ameloblastic fibro-odontoma. ( 30451090 )
2018
7
Ameloblastic Fibro-Odontoma in an Adolescent: A Case Report and Review of Literature. ( 30085878 )
2018
8
Surgical Management of Complex Odontoma Associated with Agenesis of a Molar. ( 30294179 )
2018
9
Compound odontoma - morphology, clinical findings and treatment. Case report. ( 30534846 )
2018
10
Giant complex odontoma in the posterior mandible: A case report and literature review. ( 30607354 )
2018
11
A Rare Case of Ameloblastic Fibro-Odontoma of Mandible with Literature Review. ( 30693255 )
2018
12
Ameloblastic Fibro-Odontoma. ( 30869592 )
2018
13
An unusual foreign object mimicking an odontoma in a patient with cleft alveolus: a case report. ( 28946895 )
2017
14
Immediate Dental Implant Placement After Removal of Complex Odontoma. ( 28922246 )
2017
15
Association Between Odontoma and Impacted Teeth. ( 28106699 )
2017
16
Ameloblastic Fibro-Odontoma of the Maxilla in a Pierre-Robin Sequence Patient. ( 28557592 )
2017
17
Association Between Odontoma and Impacted Teeth. ( 28468159 )
2017
18
Compound Odontoma in Anterior Mandible-A Case Report. ( 28814937 )
2017
19
Giant Complex Odontoma of Mandible: A Spectacular Case Report. ( 28839489 )
2017
20
A rare case report of an adenomatoid odontogenic tumor associated with odontoma in the maxilla. ( 28863377 )
2017
21
Spontaneous Peripheral Ameloblastic Odontoma in a Male Sprague-Dawley Rat. ( 28503263 )
2017
22
Ameloblastic Fibro-Odontoma in a 7-Month-Old Infant: A Case Report. ( 29034280 )
2017
23
Ameloblastic Fibro-odontoma with a Predominant Radiopaque Component. ( 29264304 )
2017
24
Ameloblastic Fibrodentinoma and Ameloblastic Fibro-Odontoma: An Updated Systematic Review of Cases Reported in the Literature. ( 28153756 )
2017
25
Autotransplantation of Odontoma-Associated Impacted Teeth-A Treatment Strategy for Satisfying Immediate Esthetic Demands: A Case Report. ( 28460214 )
2017
26
Surgical Access to a Complex Composite Odontoma via Sagittal Split Osteotomy of the Mandible. ( 29441249 )
2017
27
Clinical, pathological, and genetic evaluations of Chinese patient with otodental syndrome and multiple complex odontoma: Case report. ( 28151902 )
2017
28
Removal of Compound Odontoma With Piezosurgery Technique. ( 28278140 )
2017
29
Peripheral osteoma, compound odontoma, focal cemento-osseous dysplasia, and cemento-ossifying fibroma in the same hemimandible: CBCT findings of an unusual case. ( 29484064 )
2017
30
Metachronous ameloblastic fibro-odontoma and dentigerous cyst in the posterior mandible. ( 29099370 )
2017
31
Timing of Surgical Removal of Odontoma in a Growing Orthodontic Patient: A Case Report. ( 29990402 )
2017
32
Dilated odontoma: A report of two cases from a radiological perspective. ( 27041914 )
2016
33
Long-term culture of human odontoma-derived cells with a Rho kinase inhibitor. ( 27514999 )
2016
34
Lateral Approach for Excision of Maxillary Incisor Pseudo-Odontoma in Prairie Dogs (Cynomys ludovicianus). ( 26709130 )
2016
35
Diagnostic Discussion. Ameloblastic fibro-odontoma. ( 27024969 )
2016
36
Peripheral Developing Odontoma or Peripheral Ameloblastic Fibroodontoma: A Rare Challenging Case. ( 26981293 )
2016
37
Erupted Large Anterior Maxillary Complex Odontoma: A Rare Dental Hamartoma. ( 27790601 )
2016
38
Dentigerous cyst arising from a complex odontoma: an unusual presentation. ( 27090549 )
2016
39
Compound composite odontoma. ( 27194882 )
2016
40
Management of a massive compound odontoma in a 9-year child. ( 27630512 )
2016
41
An Erupted Dilated Odontoma: A Rare Presentation. ( 26989523 )
2016
42
Peripheral Tumor with Osteodentin and Cementum-like Material in an Infant: Odontogenic Hamartoma or Odontoma? ( 27098720 )
2016
43
Diverse calcification patterns of ameloblastic fibro-odontoma on radiographic examination. ( 28025437 )
2016
44
Campylorrhinus lateralis, Bilateral microphthalmia and odontoma temporalis in an Oldenburg Foal. ( 26825866 )
2016
45
Large ameloblastic fibro-odontoma in a 7-year-old girl with analysis of 108 cases. ( 27563600 )
2016
46
Odontoma in a 255-Million-Year-Old Mammalian Forebear. ( 27930769 )
2016
47
Ameloblastic fibroodontoma or complex odontoma: Two faces of the same coin. ( 28163488 )
2016
48
Extensive Mandibular Ameloblastic Fibro-Odontoma. ( 27428924 )
2016
49
Multiple complex odontoma of the maxilla and mandible-reply. ( 26972543 )
2016
50
Management of a Compound Odontoma in the Primary Dentition. ( 27620522 )
2016

Variations for Odontoma

Expression for Odontoma

Search GEO for disease gene expression data for Odontoma.

Pathways for Odontoma

GO Terms for Odontoma

Cellular components related to Odontoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.86 KRT14 KRT18 KRT19 KRT5 KRT8 PCNA
2 keratin filament GO:0045095 9.46 KRT14 KRT18 KRT5 KRT8
3 apicolateral plasma membrane GO:0016327 9.4 KRT19 KRT8
4 costamere GO:0043034 9.37 KRT19 KRT8
5 dystrophin-associated glycoprotein complex GO:0016010 9.32 KRT19 KRT8
6 cell periphery GO:0071944 9.26 KRT14 KRT18 KRT19 KRT8
7 intermediate filament GO:0005882 9.17 KRT14 KRT18 KRT19 KRT5 KRT8 NES

Biological processes related to Odontoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 viral process GO:0016032 9.55 KRT18 KRT19 KRT8 PCNA VIM
2 extrinsic apoptotic signaling pathway GO:0097191 9.43 KRT18 KRT8
3 sarcomere organization GO:0045214 9.4 KRT19 KRT8
4 hemidesmosome assembly GO:0031581 9.37 KRT14 KRT5
5 keratinization GO:0031424 9.35 KRT14 KRT18 KRT19 KRT5 KRT8
6 hepatocyte apoptotic process GO:0097284 9.32 KRT18 KRT8
7 cell differentiation involved in embryonic placenta development GO:0060706 9.26 KRT19 KRT8
8 cornification GO:0070268 9.02 KRT14 KRT18 KRT19 KRT5 KRT8

Molecular functions related to Odontoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 9.46 KRT18 KRT8 NES VIM
2 keratin filament binding GO:1990254 9.26 KRT14 VIM
3 scaffold protein binding GO:0097110 9.26 KRT18 KRT5 KRT8 VIM
4 structural constituent of cytoskeleton GO:0005200 9.02 KRT14 KRT19 KRT5 TUBB3 VIM

Sources for Odontoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
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43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
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52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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