Aliases & Classifications for Odontoma

MalaCards integrated aliases for Odontoma:

Name: Odontoma 54 56 74

Classifications:



External Ids:

UMLS 74 C0028882

Summaries for Odontoma

MalaCards based summary : Odontoma is related to ameloblastoma and odontoma-dysphagia syndrome. An important gene associated with Odontoma is LHX8 (LIM Homeobox 8), and among its related pathways/superpathways are Keratinization and Cytoskeletal Signaling. Affiliated tissues include skin, bone and testes, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Wikipedia : 77 An odontoma, also known as an odontome, is a benign tumour linked to tooth development. Specifically, it... more...

Related Diseases for Odontoma

Diseases related to Odontoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 127)
# Related Disease Score Top Affiliating Genes
1 ameloblastoma 30.5 KRT14 KRT18 KRT8 PCNA
2 odontoma-dysphagia syndrome 12.6
3 encephalocraniocutaneous lipomatosis 11.5
4 calcifying epithelial odontogenic tumor 11.1
5 fibroma 10.4
6 brooke-spiegler syndrome 10.4 KRT14 KRT8
7 neurenteric cyst 10.4 KRT18 KRT8
8 benign breast adenomyoepithelioma 10.3 KRT14 KRT5
9 breast adenomyoepithelioma 10.3 KRT14 KRT5
10 lichen planopilaris 10.3 KRT14 KRT5
11 epidermolysis bullosa simplex, autosomal recessive 1 10.3 KRT14 KRT5
12 large cell acanthoma 10.3 KRT14 KRT5
13 epidermolysis bullosa simplex, localized 10.3 KRT14 KRT5
14 epidermolysis bullosa simplex, generalized 10.3 KRT14 KRT5
15 breast squamous cell carcinoma 10.3 KRT14 KRT5
16 cryptogenic cirrhosis 10.3 KRT18 KRT8
17 epidermolysis bullosa simplex with mottled pigmentation 10.3 KRT14 KRT5
18 breast myoepithelial neoplasm 10.3 KRT14 KRT5
19 vesiculobullous skin disease 10.3 KRT14 KRT5
20 basaloid squamous cell carcinoma 10.3 KRT14 KRT8
21 breast benign neoplasm 10.3 KRT14 KRT5
22 prostate squamous cell carcinoma 10.3 KRT5 KRT8
23 thoracic benign neoplasm 10.3 KRT14 KRT5
24 lymphoepithelioma-like thymic carcinoma 10.3 KRT18 KRT5
25 schneiderian carcinoma 10.3 KRT18 KRT5
26 nasal cavity squamous cell carcinoma 10.3 KRT5 KRT8
27 epidermolysis bullosa simplex, dowling-meara type 10.3 KRT14 KRT5
28 atypical choroid plexus papilloma 10.3 KRT5 KRT8
29 lipid-rich carcinoma 10.3 KRT14 KRT5
30 breast secretory carcinoma 10.3 KRT5 KRT8
31 sweat gland disease 10.3 KRT14 KRT5
32 sarcomatoid squamous cell skin carcinoma 10.3 KRT5 KRT8
33 teeth, supernumerary 10.3
34 tonsil cancer 10.3 KRT14 KRT5
35 pre-malignant neoplasm 10.3 KRT14 KRT5
36 ameloblastic carcinoma 10.3 KRT14 VIM
37 nephrogenic adenofibroma 10.3 KRT18 KRT8
38 adenoid squamous cell carcinoma 10.2 KRT8 VIM
39 leukoplakia 10.2 KRT8 PCNA
40 pleomorphic liposarcoma 10.2 KRT8 VIM
41 sinusitis 10.2
42 long-chain 3-hydroxyacyl-coa dehydrogenase deficiency 10.2 KRT8 VIM
43 oropharynx cancer 10.2 KRT14 KRT5
44 metanephric adenoma 10.2 KRT18 VIM
45 lymphangiomatosis 10.2 PCNA VIM
46 ovarian mucinous cystadenocarcinoma 10.2 PCNA VIM
47 mucinous cystadenocarcinoma 10.2 PCNA VIM
48 optic nerve neoplasm 10.2 KRT5 NES
49 breast fibroadenoma 10.2 KRT14 KRT8
50 apocrine sweat gland neoplasm 10.2 KRT14 KRT5 KRT8

Graphical network of the top 20 diseases related to Odontoma:



Diseases related to Odontoma

Symptoms & Phenotypes for Odontoma

GenomeRNAi Phenotypes related to Odontoma according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.47 KRT5
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-154 9.47 KRT18
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-17 9.47 KRT18 KRT5
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.47 KRT5 KRT8
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.47 KRT5
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.47 KRT18
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-40 9.47 KRT8
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.47 KRT18 KRT5 KRT8
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.47 KRT18
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.47 KRT5

MGI Mouse Phenotypes related to Odontoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.35 KRT14 KRT19 KRT5 KRT8 LHX8
2 mortality/aging MP:0010768 9.28 KRT14 KRT18 KRT19 KRT5 KRT8 LHX8

Drugs & Therapeutics for Odontoma

Search Clinical Trials , NIH Clinical Center for Odontoma

Genetic Tests for Odontoma

Anatomical Context for Odontoma

MalaCards organs/tissues related to Odontoma:

42
Skin, Bone, Testes, Liver, Heart, Prostate, Thymus

Publications for Odontoma

Articles related to Odontoma:

(show top 50) (show all 548)
# Title Authors Year
1
Mixed odontogenic tumors in four young dogs: ameloblastic fibroma and ameloblastic fibro-odontoma. ( 30451090 )
2019
2
Incidentally detected odontoma within a dentigerous cyst. ( 30840819 )
2019
3
Pigmented calcifying cystic odontogenic tumor associated with compound odontoma: Report of a rare case and review. ( 30967731 )
2019
4
Anxiolysis in the Surgical Management of a Compound Odontoma in a Pediatric Patient. ( 31065390 )
2019
5
Gingival complex odontoma: a rare case report with a review of the literature. ( 29515984 )
2018
6
A Bag of Marbles: A Fascinating Compound Odontoma of the Maxilla. ( 29663916 )
2018
7
Ameloblastic fibro-odontoma with chondroid tissue formation. ( 29692665 )
2018
8
Rare case of bilateral complex odontoma associated with mandibular bicuspids. ( 29922342 )
2018
9
Ameloblastic Fibro-Odontoma in an Adolescent: A Case Report and Review of Literature. ( 30085878 )
2018
10
Surgical Management of Complex Odontoma Associated with Agenesis of a Molar. ( 30294179 )
2018
11
Compound odontoma - morphology, clinical findings and treatment. Case report. ( 30534846 )
2018
12
Giant complex odontoma in the posterior mandible: A case report and literature review. ( 30607354 )
2018
13
A Rare Case of Ameloblastic Fibro-Odontoma of Mandible with Literature Review. ( 30693255 )
2018
14
Ameloblastic Fibro-Odontoma. ( 30869592 )
2018
15
Peripheral osteoma, compound odontoma, focal cemento-osseous dysplasia, and cemento-ossifying fibroma in the same hemimandible: CBCT findings of an unusual case. ( 29484064 )
2017
16
Odontoma in a 255-Million-Year-Old Mammalian Forebear. ( 27930769 )
2017
17
Clinical, pathological, and genetic evaluations of Chinese patient with otodental syndrome and multiple complex odontoma: Case report. ( 28151902 )
2017
18
Ameloblastic Fibrodentinoma and Ameloblastic Fibro-Odontoma: An Updated Systematic Review of Cases Reported in the Literature. ( 28153756 )
2017
19
Removal of Compound Odontoma With Piezosurgery Technique. ( 28278140 )
2017
20
Autotransplantation of Odontoma-Associated Impacted Teeth-A Treatment Strategy for Satisfying Immediate Esthetic Demands: A Case Report. ( 28460214 )
2017
21
Association Between Odontoma and Impacted Teeth. ( 28468159 )
2017
22
Spontaneous Peripheral Ameloblastic Odontoma in a Male Sprague-Dawley Rat. ( 28503263 )
2017
23
Ameloblastic Fibro-Odontoma of the Maxilla in a Pierre-Robin Sequence Patient. ( 28557592 )
2017
24
Compound Odontoma in Anterior Mandible-A Case Report. ( 28814937 )
2017
25
Giant Complex Odontoma of Mandible: A Spectacular Case Report. ( 28839489 )
2017
26
A rare case report of an adenomatoid odontogenic tumor associated with odontoma in the maxilla. ( 28863377 )
2017
27
Immediate Dental Implant Placement After Removal of Complex Odontoma. ( 28922246 )
2017
28
An unusual foreign object mimicking an odontoma in a patient with cleft alveolus: a case report. ( 28946895 )
2017
29
Ameloblastic Fibro-Odontoma in a 7-Month-Old Infant: A Case Report. ( 29034280 )
2017
30
Metachronous ameloblastic fibro-odontoma and dentigerous cyst in the posterior mandible. ( 29099370 )
2017
31
Ameloblastic Fibro-odontoma with a Predominant Radiopaque Component. ( 29264304 )
2017
32
Surgical Access to a Complex Composite Odontoma via Sagittal Split Osteotomy of the Mandible. ( 29441249 )
2017
33
Timing of Surgical Removal of Odontoma in a Growing Orthodontic Patient: A Case Report. ( 29990402 )
2017
34
Campylorrhinus lateralis, Bilateral microphthalmia and odontoma temporalis in an Oldenburg Foal. ( 26825866 )
2016
35
Ameloblastic Fibro-Odontoma in a 4-Year-Old Boy. ( 27307963 )
2016
36
Extensive Mandibular Ameloblastic Fibro-Odontoma. ( 27428924 )
2016
37
Long-term culture of human odontoma-derived cells with a Rho kinase inhibitor. ( 27514999 )
2016
38
Large ameloblastic fibro-odontoma in a 7-year-old girl with analysis of 108 cases. ( 27563600 )
2016
39
Management of a Compound Odontoma in the Primary Dentition. ( 27620522 )
2016
40
Management of a massive compound odontoma in a 9-year child. ( 27630512 )
2016
41
Erupted Large Anterior Maxillary Complex Odontoma: A Rare Dental Hamartoma. ( 27790601 )
2016
42
Diverse calcification patterns of ameloblastic fibro-odontoma on radiographic examination. ( 28025437 )
2016
43
Ameloblastic fibroodontoma or complex odontoma: Two faces of the same coin. ( 28163488 )
2016
44
Primordial Odontogenic Cyst with Induction Phenomenon (Zonal Fibroblastic Hypercellularity) and Dentinoid Material Versus Archegonous Cystic Odontoma: You Choose! ( 26156422 )
2016
45
Clinical parameter of odontoma with special emphasis on treatment of impacted teeth-a retrospective multicentre study and literature review. ( 26612404 )
2016
46
Lateral Approach for Excision of Maxillary Incisor Pseudo-Odontoma in Prairie Dogs (Cynomys ludovicianus). ( 26709130 )
2016
47
Archegonous Cystic Odontoma Is Not Necessarily Primordial. ( 26843411 )
2016
48
Response to the Letter Entitled "Archegonous Cystic Odontoma Is Not Necessarily Primordial" by Ide et al. ( 26857026 )
2016
49
Multiple complex odontoma of the maxilla and mandible--reply. ( 26972543 )
2016
50
Peripheral Developing Odontoma or Peripheral Ameloblastic Fibroodontoma: A Rare Challenging Case. ( 26981293 )
2016

Variations for Odontoma

Expression for Odontoma

Search GEO for disease gene expression data for Odontoma.

Pathways for Odontoma

GO Terms for Odontoma

Cellular components related to Odontoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.86 KRT14 KRT18 KRT19 KRT5 KRT8 PCNA
2 keratin filament GO:0045095 9.46 KRT14 KRT18 KRT5 KRT8
3 apicolateral plasma membrane GO:0016327 9.4 KRT19 KRT8
4 costamere GO:0043034 9.37 KRT19 KRT8
5 dystrophin-associated glycoprotein complex GO:0016010 9.32 KRT19 KRT8
6 cell periphery GO:0071944 9.26 KRT14 KRT18 KRT19 KRT8
7 intermediate filament GO:0005882 9.17 KRT14 KRT18 KRT19 KRT5 KRT8 NES

Biological processes related to Odontoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 viral process GO:0016032 9.55 KRT18 KRT19 KRT8 PCNA VIM
2 extrinsic apoptotic signaling pathway GO:0097191 9.43 KRT18 KRT8
3 sarcomere organization GO:0045214 9.4 KRT19 KRT8
4 hemidesmosome assembly GO:0031581 9.37 KRT14 KRT5
5 keratinization GO:0031424 9.35 KRT14 KRT18 KRT19 KRT5 KRT8
6 hepatocyte apoptotic process GO:0097284 9.32 KRT18 KRT8
7 cell differentiation involved in embryonic placenta development GO:0060706 9.26 KRT19 KRT8
8 cornification GO:0070268 9.02 KRT14 KRT18 KRT19 KRT5 KRT8

Molecular functions related to Odontoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 9.33 KRT18 NES VIM
2 keratin filament binding GO:1990254 9.26 KRT14 VIM
3 scaffold protein binding GO:0097110 9.26 KRT18 KRT5 KRT8 VIM
4 structural constituent of cytoskeleton GO:0005200 9.02 KRT14 KRT19 KRT5 TUBB3 VIM

Sources for Odontoma

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70 SNOMED-CT via HPO
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75 UMLS via Orphanet
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