MCID: OLF001
MIFTS: 17

Olfactory Nerve Disease

Categories: Neuronal diseases, Smell/Taste diseases

Aliases & Classifications for Olfactory Nerve Disease

MalaCards integrated aliases for Olfactory Nerve Disease:

Name: Olfactory Nerve Disease 12 15
Olfactory Nerve Diseases 43 71
Disorder of Olfactory [1st] Nerve 12
Disorder of Olfactory Nerve 12
Disorder of 1st Nerve 12

Classifications:



External Ids:

Disease Ontology 12 DOID:367
ICD9CM 34 352.0
MeSH 43 D020431
NCIt 49 C27210
SNOMED-CT 67 68982002
ICD10 32 G52.0
UMLS 71 C0751937

Summaries for Olfactory Nerve Disease

Disease Ontology : 12 A brain disease that is characterized by nerve injury located in olfactory nerve, occurring as a result of normal aging, trauma, mass lesion or other insult, and has symptom impaired sense of smell, has symptom anosmia or loss of smell.

MalaCards based summary : Olfactory Nerve Disease, is also known as olfactory nerve diseases, and has symptoms including anosmia and impaired sense of smell. An important gene associated with Olfactory Nerve Disease is B4GALT1 (Beta-1,4-Galactosyltransferase 1). Affiliated tissues include olfactory nerve and brain, and related phenotypes are endocrine/exocrine gland and reproductive system

Wikipedia : 74 The olfactory nerve is typically considered the first cranial nerve, or simply CN I, that contains... more...

Related Diseases for Olfactory Nerve Disease

Symptoms & Phenotypes for Olfactory Nerve Disease

Symptoms:

12
  • anosmia
  • impaired sense of smell

MGI Mouse Phenotypes related to Olfactory Nerve Disease:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.35 B4GALT1 GRB2 HTR3A SERPINB3 SYCN
2 reproductive system MP:0005389 9.02 B4GALT1 BRPF3 GRB2 HTR3A SERPINB3

Drugs & Therapeutics for Olfactory Nerve Disease

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Intranasal Injection of Platelet-rich Plasma Versus Saline for Treatment of Olfactory Dysfunction Not yet recruiting NCT04406584

Search NIH Clinical Center for Olfactory Nerve Disease

Cochrane evidence based reviews: olfactory nerve diseases

Genetic Tests for Olfactory Nerve Disease

Anatomical Context for Olfactory Nerve Disease

The Foundational Model of Anatomy Ontology organs/tissues related to Olfactory Nerve Disease:

19
Olfactory Nerve

MalaCards organs/tissues related to Olfactory Nerve Disease:

40
Brain

Publications for Olfactory Nerve Disease

Variations for Olfactory Nerve Disease

Expression for Olfactory Nerve Disease

Search GEO for disease gene expression data for Olfactory Nerve Disease.

Pathways for Olfactory Nerve Disease

GO Terms for Olfactory Nerve Disease

Cellular components related to Olfactory Nerve Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 secretory granule membrane GO:0030667 8.62 SYCN B4GALT1

Biological processes related to Olfactory Nerve Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 leukocyte migration GO:0050900 8.62 GRB2 B4GALT1

Sources for Olfactory Nerve Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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