MCID: OLG001
MIFTS: 45

Oligospermia

Categories: Reproductive diseases

Aliases & Classifications for Oligospermia

MalaCards integrated aliases for Oligospermia:

Name: Oligospermia 12 29 6 43 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:14228
ICD9CM 34 606.1
MeSH 43 D009845
NCIt 49 C34860
ICD10 32 N46.1
UMLS 71 C0028960

Summaries for Oligospermia

Disease Ontology : 12 A male fertility issue defined as a low sperm concentration in the ejaculate.

MalaCards based summary : Oligospermia is related to infertility and varicocele. An important gene associated with Oligospermia is AR (Androgen Receptor), and among its related pathways/superpathways are Endometrial cancer and Pathways in cancer. The drugs Metformin and Sodium citrate have been mentioned in the context of this disorder. Affiliated tissues include testes, testis and pituitary, and related phenotypes are endocrine/exocrine gland and growth/size/body region

Wikipedia : 74 Terms oligospermia, oligozoospermia, and low sperm count refer to semen with a low concentration of... more...

Related Diseases for Oligospermia

Diseases related to Oligospermia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 76)
# Related Disease Score Top Affiliating Genes
1 infertility 31.3 PRL KLHL10 EPPIN CFTR AR
2 varicocele 31.3 PRL GSTM1 FAM47C AR
3 male infertility 31.0 KLHL10 KITLG GSTM1 EPPIN CFTR AR
4 impotence 30.9 PRL EPPIN AR
5 alopecia 30.6 SRD5A2 PRL AR
6 gynecomastia 30.6 SRD5A2 PRL AR
7 testicular cancer 30.3 KITLG GSTP1 DNMT1 AR
8 cryptorchidism, unilateral or bilateral 29.3 SRD5A2 PRL KITLG KIT GNRHR EPPIN
9 bronchiectasis oligospermia 12.2
10 y chromosome infertility 11.6
11 spermatogenic failure, y-linked, 2 11.4
12 spermatogenic failure 4 11.2
13 androgen insensitivity, partial 11.2
14 azoospermia 10.9
15 partial deletion of y 10.5
16 alopecia, androgenetic, 1 10.4 SRD5A2 AR
17 acrokeratoderma, hereditary papulotranslucent 10.4 PRL CFTR
18 male infertility with azoospermia or oligozoospermia due to single gene mutation 10.4 KLHL10 CFTR
19 androgenic alopecia 10.4 SRD5A2 PRL AR
20 transsexualism 10.4 SRD5A2 AR
21 extracutaneous mastocytoma 10.4 KITLG KIT
22 hypogonadism 10.4
23 cutaneous solitary mastocytoma 10.4 KITLG KIT
24 mast-cell sarcoma 10.4 KITLG KIT
25 ovarian gonadoblastoma 10.3 PRL KIT
26 pseudovaginal perineoscrotal hypospadias 10.3 SRD5A2 AR
27 dysgerminoma of ovary 10.3 KITLG KIT
28 oligoasthenoteratozoospermia 10.3 GSTP1 GSTM1 AR
29 sm-ahnmd 10.3 KITLG KIT
30 hypogonadotropic hypogonadism 23 without anosmia 10.3 GNRHR EPPIN
31 testicular germ cell tumor 10.3 KITLG KIT AR
32 alcoholic pancreatitis 10.3 GSTP1 GSTM1 CFTR
33 hypogonadotropic hypogonadism 10.3
34 germinoma 10.3 PRL MIR122 KIT
35 prostatic hypertrophy 10.2 SRD5A2 EPPIN AR
36 dowling-degos disease 1 10.2 KITLG KIT
37 mutagen sensitivity 10.2 GSTM1 DNMT1
38 pseudohermaphroditism 10.2 SRD5A2 EPPIN AR
39 spermatogenic failure 3 10.2
40 mumps 10.2
41 premature ejaculation 10.2
42 pustulosis of palm and sole 10.2
43 psoriasis 10.2
44 bronchiectasis 10.2
45 ovarian benign neoplasm 10.1 PRL EPPIN
46 bladder urothelial carcinoma 10.1 SRD5A2 KIT GSTP1 AR
47 testicular disease 10.1 KITLG KIT EPPIN AR
48 hypogonadotropic hypogonadism 7 with or without anosmia 10.0
49 schizophrenia 10.0
50 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.0

Comorbidity relations with Oligospermia via Phenotypic Disease Network (PDN):


Prostate Cancer

Graphical network of the top 20 diseases related to Oligospermia:



Diseases related to Oligospermia

Symptoms & Phenotypes for Oligospermia

MGI Mouse Phenotypes related to Oligospermia:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 10.15 AR CFTR GNRHR KIT KITLG KLHL10
2 growth/size/body region MP:0005378 10.1 AR CFTR DNMT1 GNRHR GSTP1 KIT
3 digestive/alimentary MP:0005381 10.06 AR CFTR DNMT1 GNRHR KIT KITLG
4 craniofacial MP:0005382 9.98 AR CFTR KIT KITLG NFKB1 PYGO2
5 integument MP:0010771 9.91 AR DNMT1 GNRHR GSTP1 KIT KITLG
6 liver/biliary system MP:0005370 9.7 AR CFTR KIT KITLG NFKB1 PRL
7 neoplasm MP:0002006 9.43 AR DNMT1 GSTP1 KIT KITLG PRL
8 reproductive system MP:0005389 9.4 AR CFTR DNMT1 GNRHR KIT KITLG

Drugs & Therapeutics for Oligospermia

Drugs for Oligospermia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 95)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Metformin Approved Phase 4 657-24-9 14219 4091
2
Sodium citrate Approved, Investigational Phase 4 68-04-2
3
Citric acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
4
Enclomiphene Investigational Phase 4 15690-57-0
5 Insulin, Globin Zinc Phase 4
6 insulin Phase 4
7 Citrate Phase 4
8 Chelating Agents Phase 4
9 Estrogen Receptor Modulators Phase 4
10 Chorionic Gonadotropin Phase 4
11 Clomiphene Phase 4
12 Anticoagulants Phase 4
13 Calcium, Dietary Phase 4
14 Zuclomiphene Phase 4
15
Calcium Nutraceutical Phase 4 7440-70-2 271
16
Testosterone enanthate Approved Phase 3 315-37-7 9416
17
Testosterone undecanoate Approved, Investigational Phase 3 5949-44-0
18
Methyltestosterone Approved Phase 3 58-18-4 6010
19
leucovorin Approved Phase 2, Phase 3 58-05-9 6006 143
20 Ginger Approved Phase 3
21
Letrozole Approved, Investigational Phase 3 112809-51-5 3902
22
Anastrozole Approved, Investigational Phase 3 120511-73-1 2187
23
Estradiol Approved, Investigational, Vet_approved Phase 3 50-28-2 5757
24
Testosterone Approved, Experimental, Investigational Phase 3 58-22-0, 481-30-1 10204 6013
25
Polyestradiol phosphate Approved Phase 3 28014-46-2
26
Folic acid Approved, Nutraceutical, Vet_approved Phase 2, Phase 3 59-30-3 6037
27 Triptolide Investigational Phase 2, Phase 3 38748-32-2
28 Mesalamine Phase 2, Phase 3 89-57-6
29 Contraceptive Agents, Male Phase 2, Phase 3
30 Cardiac Glycosides Phase 2, Phase 3
31 Alkylating Agents Phase 2, Phase 3
32 Contraceptive Agents Phase 2, Phase 3
33 Tripterygium Phase 2, Phase 3
34 Testosterone 17 beta-cypionate Phase 3
35 Trace Elements Phase 2, Phase 3
36 Vitamins Phase 2, Phase 3
37 Nutrients Phase 2, Phase 3
38 Micronutrients Phase 2, Phase 3
39 Estrogen Antagonists Phase 3
40 Estrogen Receptor Antagonists Phase 3
41 Estrogens Phase 3
42 Vitamin B Complex Phase 2, Phase 3
43 Hematinics Phase 2, Phase 3
44 Folate Phase 2, Phase 3
45 Vitamin B9 Phase 2, Phase 3
46 Hormones Phase 3
47 Antineoplastic Agents, Hormonal Phase 3
48 Aromatase Inhibitors Phase 3
49 Estradiol 17 beta-cypionate Phase 3
50 Estradiol 3-benzoate Phase 3

Interventional clinical trials:

(show all 41)
# Name Status NCT ID Phase Drugs
1 Effectiveness and Safety of uFSH for Severe Oligospermia or Azoospermia:A Multi-center,Open,Randomized,Interventional,and Phase4 Trial in China Unknown status NCT02307994 Phase 4 75IU uFSH
2 Metformin for the Treatment of Unexplained Oligozspermia and Azoospermia Unknown status NCT01529177 Phase 4 Metformin / clomid / hCG;Clomiphene citrate / hCG
3 Prospective Experimental of Tripterygium Glycoside in the Treatment of Crohn's Disease for Induction Remission Unknown status NCT02044952 Phase 2, Phase 3 Mesalazine, Tripterygium glycosides
4 Effect of Red and White Bahman on Semen Parameters,Testosteron ,LH, FSH and Defragmentation of DNA . A Double Blind Randomised Clinical Trial (Phase 3) Unknown status NCT02998593 Phase 3 Bahman capsules;Placebo
5 7 NUTS Study . A Randomized Dietary Intervention Trial on the Influence of Diet on Human Sperm Quality in Subfertile Men. Unknown status NCT02063256 Phase 2, Phase 3
6 Effect of Treatment With Myo-inositol on Human Semen Parameters in Patients Undergoing IVF Cycles Completed NCT01828710 Phase 2, Phase 3
7 Phase 3 of Study on Effects of New Herbal Mixture on Men Infertility Completed NCT01895816 Phase 3
8 Effect of Letrozole on Seminal Parameters in Men With Non Obstructive Azoospermia and Severe Oligozoospermia. Completed NCT02900105 Phase 3 Letrozole
9 The Role of Aromatase Inhibitors in the Treatment of Infertility in Obese Male Terminated NCT00440180 Phase 3 Anastrozole;Placebo
10 Pilot Study on the Effects of FSH Treatment on the Epigenetic Characteristics of Spermatozoa in Infertile Patients With Severe Oligozoospermia Terminated NCT02605070 Phase 3 Bravelle
11 Safety and Efficacy of Chandrakanthi Choornam in Oligospermia - A Preclinical and Clinical Study Completed NCT02234206 Phase 2 Chandrakanthi Choornam (CKC)
12 A 5-year Prospective, Placebo-controlled, Crossover Evaluation of the Efficacy and Tolerability of Low-dose Lisinopril in Normotensives With Idiopathic Oligospermic Infertility Completed NCT01409837 Phase 2 Lisinopril
13 Autologous Hematopoietic Stem Cell Mobilization (Plerixafor) and Immunologic Reset in New Onset Type 1 Diabetes Mellitus Recruiting NCT03182426 Phase 1, Phase 2 Plerixafor;Alemtuzumab;Anakinra;Etanercept;Liraglutide
14 Denosumab and Male Infertility: a Randomized Controlled Double-blinded Intervention Study Active, not recruiting NCT03030196 Phase 2 Denosumab
15 Efficiency Evaluation of Adipose-Derived Adult Stromal Vascular Cells in Patients With Spermatogenesis Disorders. Enrolling by invitation NCT03762967 Phase 2 Standard therapy.
16 Vitamins ,Minerals and Amino Acids Supplement Intake in Infertile Men;the Effect on Sperm Parameters,Fertilization Rate and Embryo Quality. A Double Blind Randomized Controlled Trial Unknown status NCT01520584
17 Investigating the Effect of Modifiable Lifestyle Factors in Severe Oligoasthenotertozoospermic Men Combined With Antioxidant Treatment Prior ICSI Unknown status NCT02752555
18 Preimplantation Genetic Screening in Patients With Male Factor Infertility Unknown status NCT02941965
19 Efficacy Study of Tripterygium Glycoside Combined With Enteral Nutrition in the Treatment of Crohn's Disease for Induction Remission Unknown status NCT01820247 enteral nutrition;Tripterygium glycosides
20 A Randomized, Controlled, Open-label Study to Assess the Efficacy of T2 Versus Azathioprine for the Maintenance of Clinical and Endoscopic Remission in Subjects With Crohn's Disease After Surgical Resection Unknown status NCT01015391 T2;Azathioprine
21 Effect of Dietary Supplementation With Omega-3 Fatty Acids on Human Sperm Characteristics, a Preliminary Study Unknown status NCT00479960 Early Phase 1
22 The Effect of Low Electrical Current on Testicular Spermatocyte Count Unknown status NCT02617173
23 Seminal Fluid's Changes Over Time: a Single Center 20 Years Experience Completed NCT04349345
24 Insulin Resistance : a New Diagnosis of the Pathogenesis of Idiopathic Oligozoospermia and Non Obstructive Azoospermia Completed NCT01509482
25 Embryo Kinetics and Sperm Quality. Depends on the Sperm Quality the Embryo Cleavage Rate? Completed NCT02155179
26 Identification and Characterization of the Methylation Abnormalities on Whole Genome Among Infertile Men Completed NCT01239186
27 Increased Testicular Cd2+ & Infertility With Varicocele ( a Varicose Vein in the Scrotum) Completed NCT00044369
28 A Retrospective Study on the Effect of Male Progressive Sperm Count After Semen Pretreatment on ICSI Fertilization Outcome Completed NCT03594201
29 Genetic Studies Spermatogenic Failure Completed NCT00548977
30 Fertility Preservation in Cases of Spermatogenesis Failure : Prospective Study for Klinefelter Syndrome With Non-mosaic Karyotype (47, XXY, Homogeneous) Completed NCT01918280
31 Management of Azoospermic Patients With Kleinfelter Syndrome Patients With Mesenchymal Stem Cell Injection Completed NCT02414295 Mesenchymal stem cell injection
32 Sperms Activation by Direct Electrical Shocks on Testis in Infertile Males Completed NCT04173052
33 The Role of Artery-Preserving Varicocelectomy in Subfertile Men With Severe Oligozoospermia; A Randomized Controlled Study Completed NCT03344588
34 Factors Associated With Quit Intention Among Male Smokers Whose Partner Got Pregnant: An Exploration Study Completed NCT03401021
35 The Effectiveness of a Video-led Smoking Cessation Intervention in Helping Male Smokers in Mainland China Whose Partner Got Pregnant to Quit Smoking: A Randomized Control Trial Completed NCT03236025
36 Is Oxidative Stress in Semen Reduced by Lifestyle Intervention Recruiting NCT03898752
37 Omega-3 Polyunsaturated Fatty Acids for the Treatment of Patients With Idiopathic Oligoasthenoteratospermia: A Double-blind, Placebo-controlled and Randomized Exploratory Clinical Trial Recruiting NCT03634644 Omega 3 fatty acid;Placebo oral capsule
38 Effect of Walnuts on Sperm Parameters and Male Fertility Active, not recruiting NCT01954498
39 Does Antioxidant Administration Improve Sperm Quality in Infertile Men Not yet recruiting NCT04256278
40 Detection of Microdeletions in the Azoospermia Factor (AZF) Regions on the Human Y Chromosome in Infertile Male Patients Suspended NCT03497728
41 Ramipril for the Treatment of Oligospermia: A Double-Blind Randomized Control Trial Terminated NCT01856361 Ramipril;Placebo

Search NIH Clinical Center for Oligospermia

Cochrane evidence based reviews: oligospermia

Genetic Tests for Oligospermia

Genetic tests related to Oligospermia:

# Genetic test Affiliating Genes
1 Oligospermia 29

Anatomical Context for Oligospermia

MalaCards organs/tissues related to Oligospermia:

40
Testes, Testis, Pituitary, Prostate, Thyroid, Liver, Ovary

Publications for Oligospermia

Articles related to Oligospermia:

(show top 50) (show all 1314)
# Title Authors PMID Year
1
Photobiomodulation restores spermatogenesis in the transient scrotal hyperthermia-induced mice. 61
32407848 2020
2
Inhibition of ferroptosis attenuates busulfan-induced oligospermia in mice. 61
32416107 2020
3
Associations of Common Single Nucleotide Polymorphisms in miR-34b/c and miR-499 with Male Infertility Caused by Oligospermia or Azoospermia in the Chinese Population. 61
32412799 2020
4
[Novel compound heterozygous LoF mutations in SRD5A2 may result in disorders of sex development]. 61
32536088 2020
5
CHD7 missense variants and clinical characteristics of Chinese males with infertility. 61
32573075 2020
6
A novel locus predicts spermatogenic recovery among childhood cancer survivors exposed to alkylating agents. 61
32554749 2020
7
Cryopreservation of single-sperm: where are we today? 61
32398019 2020
8
Determination of 27 amino acids' levels in seminal plasma of asthenospermia and oligospermia patients and diagnostic value analysis. 61
32126460 2020
9
A clinical algorithm for management of fertility in adolescents with the Klinefelter syndrome. 61
32235276 2020
10
First custom next-generation sequencing infertility panel in Latin America: design and first results. 61
32155011 2020
11
Indian Sarsaparilla (Hemidesmus indicus): Recent progress in research on ethnobotany, phytochemistry and pharmacology. 61
32007632 2020
12
Whole-Exome Sequencing of a Large Chinese Azoospermia and Severe Oligospermia Cohort Identifies Novel Infertility Causative Variants and Genes. 61
32469048 2020
13
Mechanistic perspective of protective effects of nilotinib against cisplatin-induced testicular injury in rats: Role of JNK/caspase-3 signaling inhibition. 61
32059174 2020
14
Low-power Density Radiations Emitted from Common Wi-Fi Routers Influence Sperm Concentration and Sperm Histomorphometric Parameters: A New Horizon on Male Infertility Treatment. 61
32337184 2020
15
Karyotypic abnormalities and molecular analysis of Y chromosome microdeletion in Iranian Azeri Turkish population infertile men. 61
31687839 2020
16
MicroRNAs association with azoospermia, oligospermia, asthenozoospermia, and teratozoospermia: a systematic review. 61
32189180 2020
17
Investigation of serum vitamin D and ischaemia-modified albumin levels in infertile Turkish men. 61
31943308 2020
18
Potential Pathogenic Bacteria in Seminal Microbiota of Patients with Different Types of Dysspermatism. 61
32327694 2020
19
Studies on the toxic effects of agrochemical pesticide (Monocrotophos) on physiological and reproductive behavior of indigenous and exotic earthworm species. 61
30897939 2020
20
How does body mass index affect semen parameters and reproductive hormones in infertile males? 61
32053100 2020
21
Increased BMI 'alone' does not negatively influence sperm function - a retrospective analysis of men attending fertility treatment with corresponding liver function results. 61
32321679 2020
22
Mosaic Ring-like Small Supernumerary Marker Chromosome and Gene Mutation in a Male With Intermittent Azoospermia: A Rare Case Report. 61
32321348 2020
23
Long-term outcome of partial P450 side-chain cleavage enzyme deficiency in three brothers: the importance of early diagnosis. 61
31917682 2020
24
Testicular stiffness in varicocele: evaluation with shear wave elastography. 61
32326674 2020
25
The association between variants in the CFTR gene and nonobstructive male infertility: A meta-analysis. 61
31820482 2020
26
Enrichment of imidacloprid and its metabolites in lizards and its toxic effects on gonads. 61
31874432 2020
27
A different look at genetic factors in individuals with non-obstructive azoospermia or oligospermia in our research study: To whom, which threshold, when, in what way? 61
32061499 2020
28
[Prenatal diagnosis for two fetuses carrying partial deletion of Y chromosome]. 61
32034751 2020
29
Genome wide association analysis on semen volume and milk yield using different strategies of imputation to whole genome sequence in French dairy goats. 61
32085723 2020
30
The role of propolis against paclitaxel-induced oligospermia, sperm abnormality, oxidative stress and DNA damage in testes of male rats. 61
31762066 2020
31
Influence of variation in global sperm DNA methylation level on the expression level of protamine genes and human semen parameters. 61
31762067 2020
32
Efficacy of follicle-stimulating hormone as a treatment of severe idiopathic oligospermia: A retrospective study. 61
32015621 2020
33
Indicators of male fertility potential in adult patients with beta-thalassemia major: a comparative study between patients undergone allogeneic stem cell transplantation and transfusion-dependent patients. 61
32161655 2020
34
Infertility secondary to an infected hydrocele: A case report. 61
31886135 2020
35
Evaluation of the inhibitory effects of vaginal microorganisms on sperm motility in vitro. 61
31853321 2020
36
Correlation between methylenetetrahydrofolate reductase gene polymorphism and oligoasthenospermia and the effects of folic acid supplementation on semen quality. 61
32038964 2019
37
Dietary fluted pumpkin seeds induce reversible oligospermia and androgen insufficiency in adult rats. 61
31081692 2019
38
Association of UHRF1 gene polymorphisms with oligospermia in Chinese males. 61
31802345 2019
39
Suppression of transforming growth factor-beta signaling enhances spermatogonial proliferation and spermatogenesis recovery following chemotherapy. 61
31886487 2019
40
Fertility management of Klinefelter syndrome. 61
31587581 2019
41
Male factor infertility and risk of death: a nationwide record-linkage study. 61
31725880 2019
42
Humanin levels in human seminal plasma and spermatozoa are related to sperm quality. 61
30920769 2019
43
Genomic Structure of Hstx2 Modifier of Prdm9-Dependent Hybrid Male Sterility in Mice. 61
31562180 2019
44
Zika Virus Causes Acute Infection and Inflammation in the Ovary of Mice Without Apparent Defects in Fertility. 61
31063544 2019
45
Reasons that should prompt a referral to a reproductive urologist: guidelines for the gynecologist and reproductive endocrinologist. 61
31723937 2019
46
Aluminium toxicosis: a review of toxic actions and effects. 61
32206026 2019
47
Y chromosome microdeletion screening using a new molecular diagnostic method in 1030 Japanese males with infertility. 61
31603142 2019
48
Association of miR-122-5p and Occludin with Sperm Density in Oligospermia Patients. 61
31637904 2019
49
[Compound Amino Acid Capsules combined with clomiphene for severe oligospermia]. 61
32233208 2019
50
[Effect on sperm quality of asthenospermia and oligospermia treated with grain-moxibustion combined with medicine therapy]. 61
31397129 2019

Variations for Oligospermia

ClinVar genetic disease variations for Oligospermia:

6 ‎‎ ‎‎ ‎‎ ‎‎
# Gene Name Type Significance ClinVarId dbSNP ID GRCh37 Pos GRCh38 Pos
1 TBC1D25 NM_002536.4(TBC1D25):c.4609C>TSNV Likely pathogenic 816940 X:48421905-48421905 X:48563517-48563517
2 HOXD13 NM_000523.4(HOXD13):c.820C>T (p.Arg274Ter)SNV Conflicting interpretations of pathogenicity 374019 rs200750564 2:176959246-176959246 2:176094518-176094518
3 46;XY;t(20;22)(q13.3;q11.2)Translocation Uncertain significance 267893
4 46;XY;t(12;14)(q15;q13)matTranslocation Uncertain significance 267936

Expression for Oligospermia

Search GEO for disease gene expression data for Oligospermia.

Pathways for Oligospermia

Pathways related to Oligospermia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.3 SRD5A2 NFKB1 KIT GSTP1 AR
2 11.83 NFKB1 KITLG KIT GSTP1 GSTM1 AR
3 11.02 KITLG KIT GSTM1
4 10.46 KITLG KIT

GO Terms for Oligospermia

Biological processes related to Oligospermia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.77 OCLN MIR509-1 KIT DNMT1 AR
2 negative regulation of gene expression GO:0010629 9.73 OCLN NFKB1 MIR509-1 DNMT1
3 spermatid development GO:0007286 9.58 PYGO2 KLHL10 KIT
4 embryonic hemopoiesis GO:0035162 9.46 KITLG KIT
5 hepoxilin biosynthetic process GO:0051122 9.32 GSTP1 GSTM1
6 ectopic germ cell programmed cell death GO:0035234 9.26 KITLG KIT
7 maintenance of DNA methylation GO:0010216 9.16 UHRF1 DNMT1
8 male gonad development GO:0008584 9.02 SRD5A2 KLHL10 KITLG KIT AR
9 male genitalia morphogenesis GO:0048808 8.96 KLHL10 AR

Molecular functions related to Oligospermia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glutathione binding GO:0043295 8.62 GSTP1 GSTM1

Sources for Oligospermia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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