Omsk Hemorrhagic Fever (OHF)

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Disease Ontology 12 DOID:992 ICD9CM 35 065.1 MeSH 44 D006481 SNOMED-CT 68 48113006 ICD10 33 A98.1

ICD10 via Orphanet 34 A98.1 UMLS via Orphanet 73 C0019103 Orphanet 59 ORPHA319266 UMLS 72 C0019103

NIH Rare Diseases : ⁵³ Omsk hemorrhagic fever (OHF), caused by Omsk hemorrhagic fever virus (OHFV), is an infection that occurs primarily in the western Siberia regions of Omsk, Novosibirsk, Kurgan and Tyumen. People can become infected from tick bites, or from contact with the blood, feces, or urine of an infected or dead animal (most commonly a rodent who was infected by a tick). Human exposure may also occur from contaminated water, in a laboratory setting, or through the milk of infected goats or sheep. No person-to-person transmission has been documented. The first signs and symptoms of OHF may begin between 3 to 8 days after exposure and may include chills, fever, nausea, headache, and severe muscle pain. Other symptoms that may occur 3 to 4 days after the first symptoms begin include vomiting, other gastrointestinal problems, and bleeding problems. In rare cases, OHF can cause hearing loss, hair loss, and behavioral or psychological problems. There is no specific treatment for OHF, but important aspects of management include hydration and taking usual precautions for people with bleeding disorders. Some people with OHF recover within 2 weeks with no complications. However, others experience a second episode of symptoms, including fever and encephalitis, about 3 weeks after the initial onset of symptoms. In up to 3% of people with OHF, the infection is fatal.

MalaCards based summary : Omsk Hemorrhagic Fever, also known as hemorrhagic fever, omsk, is related to encephalitis and tick-borne encephalitis, and has symptoms including fever, headache and stiff neck. An important gene associated with Omsk Hemorrhagic Fever is CCL5 (C-C Motif Chemokine Ligand 5), and among its related pathways/superpathways are PEDF Induced Signaling and Akt Signaling. Affiliated tissues include cerebellum.

Disease Ontology : ¹² A viral infectious disease that is a hemorrhagic fever, has material basis in Omsk hemorrhagic fever virus, which is transmitted by Dermacentor and transmitted by Ixodes species of ticks. The infection has symptom fever, has symptom chills, has symptom headache, has symptom pain in lower and upper extremities, has symptom stiff neck, has symptom papulovesicular rash on the soft palate, has symptom cervical lymphadenopathy, has symptom conjunctival suffusion, has symptom blood in the urine, and has symptom blood in the sputum.

CDC : ³ Omsk hemorrhagic fever (OHF) is caused by Omsk hemorrhagic fever virus (OHFV), a member of the virus family Flaviviridae. OHF was described between 1945 and 1947 in Omsk, Russia from patients with hemorrhagic fever. Rodents serve as the primary host for OHFV, which is transmitted to rodents from the bite of an infected tick. Common tick vectors include Dermacentor reticulatus, Dermacentor marginatus, Ixodes persulcatus and common rodents infected with OHFV include the muskrat (Ondatra zibethica), water vole (Arvicola terrestris), and narrow-skulled voles (Microtus gregalis). Muskrats are not native to the Omsk region but were introduced to the area and are now a common target for hunters and trappers. When infected with the virus, muskrats can become ill and die. OHF occurs in the western Siberia regions of Omsk, Novosibirsk, Kurgan and Tyumen.

Wikipedia : ⁷⁵ Omsk hemorrhagic fever is a viral hemorrhagic fever caused by a... more...

Search Clinical Trials , NIH Clinical Center for Omsk Hemorrhagic Fever

Search GEO for disease gene expression data for Omsk Hemorrhagic Fever.