MCID: ONC001
MIFTS: 27

Oncocytic Breast Carcinoma

Categories: Cancer diseases

Aliases & Classifications for Oncocytic Breast Carcinoma

MalaCards integrated aliases for Oncocytic Breast Carcinoma:

Name: Oncocytic Breast Carcinoma 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:6585
NCIt 50 C40366
UMLS 70 C1518574

Summaries for Oncocytic Breast Carcinoma

Disease Ontology : 12 A breast adenocarcinoma that is characterized by abundant eosinophilic cytoplasm due to large numbers of mitochondria.

MalaCards based summary : Oncocytic Breast Carcinoma is related to anal canal paget's disease and anal paget's disease, and has symptoms including pain An important gene associated with Oncocytic Breast Carcinoma is PIP (Prolactin Induced Protein), and among its related pathways/superpathways are Estrogen signaling pathway (KEGG) and Signaling by ERBB4. Affiliated tissues include breast, ovary and liver, and related phenotypes are cellular and digestive/alimentary

Related Diseases for Oncocytic Breast Carcinoma

Diseases related to Oncocytic Breast Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 254)
# Related Disease Score Top Affiliating Genes
1 anal canal paget's disease 10.2 PIP KRT7
2 anal paget's disease 10.2 PIP KRT7
3 gastric signet ring cell adenocarcinoma 10.2 PIP KRT7
4 ceruminoma 10.2 PIP KRT7
5 spiradenoma 10.2 KRT7 KRT14
6 malignant acrospiroma 10.2 PIP KRT7
7 cutaneous mucoepidermoid carcinoma 10.2 PIP KRT7
8 bartholin's gland carcinoma 10.2 PIP KRT7
9 eccrine adenocarcinoma 10.2 PIP KRT7
10 eyelid carcinoma 10.2 PIP KRT7
11 malignant syringoma 10.2 PIP KRT7
12 anal canal adenocarcinoma 10.2 PIP KRT7
13 erysipeloid 10.2 PIP KRT7
14 clear cell hidradenoma 10.2 PIP KRT7
15 hidradenoma 10.2 PIP KRT7
16 eccrine sweat gland cancer 10.2 PIP KRT7
17 hidrocystoma 10.2 PIP KRT7
18 eccrine acrospiroma 10.2 PIP KRT7
19 dacryocystocele 10.2 PIP KRT7
20 chronic inflammation of lacrimal passage 10.2 PIP KRT7
21 tinea cruris 10.2 PIP KRT7
22 myoepithelial carcinoma 10.2 KRT7 KRT14
23 squamous cell bile duct carcinoma 10.2 KRT7 KRT14
24 lipoadenoma 10.2 KRT7 KRT14
25 large cell acanthoma 10.2 KRT7 KRT14
26 papillary cystadenocarcinoma 10.2 PIP KRT7
27 clear cell basal cell carcinoma 10.2 KRT7 KRT14
28 laryngeal mucoepidermoid carcinoma 10.1 KRT14 ERBB2
29 anal canal carcinoma 10.1 PIP KRT7
30 lacrimal gland carcinoma 10.1 PIP KRT7
31 benign peritoneal mesothelioma 10.1 KRT7 KRT14
32 epithelial-myoepithelial carcinoma 10.1 KRT7 KRT14
33 prostate neuroendocrine neoplasm 10.1 KRT7 AR
34 bladder lateral wall cancer 10.1 KRT7 ERBB2
35 basaloid squamous cell carcinoma 10.1 KRT7 KRT14
36 mixed fibrolamellar hepatocellular carcinoma 10.1 KRT7 ERBB2
37 breast myoepithelial carcinoma 10.1 PGR KRT14
38 polyp of corpus uteri 10.1 PGR KRT14
39 granulosa cell tumor of the ovary 10.1 KRT7 ERBB2
40 urethral villous adenoma 10.1 PGR KRT7
41 bladder adenocarcinoma 10.1 KRT7 ERBB2
42 external ear carcinoma 10.1 PGR KRT7
43 benign metastasizing leiomyoma 10.1 PGR KRT7
44 pleomorphic adenoma carcinoma 10.1 ERBB2 AR
45 pulmonary sclerosing hemangioma 10.1 KRT7 AR
46 renal oncocytoma 10.1 KRT7 KRT14
47 mature teratoma 10.1 KRT7 ERBB2
48 cavernous hemangioma 10.0 KRT7 KRT14
49 pancreatic mucinous cystadenoma 10.0 PGR KRT7
50 cystadenoma 10.0 PGR KRT7

Graphical network of the top 20 diseases related to Oncocytic Breast Carcinoma:



Diseases related to Oncocytic Breast Carcinoma

Symptoms & Phenotypes for Oncocytic Breast Carcinoma

UMLS symptoms related to Oncocytic Breast Carcinoma:


pain

MGI Mouse Phenotypes related to Oncocytic Breast Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.87 AR ERBB2 ESR1 KRT14 KRT7 PGR
2 digestive/alimentary MP:0005381 9.65 AR ERBB2 ESR1 KRT14 PIP
3 endocrine/exocrine gland MP:0005379 9.63 AR ERBB2 ESR1 KRT14 PGR PIP
4 neoplasm MP:0002006 9.35 AR ERBB2 ESR1 KRT14 PGR
5 reproductive system MP:0005389 9.1 AR ERBB2 ESR1 KRT14 PGR PIP

Drugs & Therapeutics for Oncocytic Breast Carcinoma

Search Clinical Trials , NIH Clinical Center for Oncocytic Breast Carcinoma

Genetic Tests for Oncocytic Breast Carcinoma

Anatomical Context for Oncocytic Breast Carcinoma

MalaCards organs/tissues related to Oncocytic Breast Carcinoma:

40
Breast, Ovary, Liver, Skin, Prostate, Cervix, Eye

Publications for Oncocytic Breast Carcinoma

Articles related to Oncocytic Breast Carcinoma:

# Title Authors PMID Year
1
Conventional Imaging and Sonoelastography Findings of Oncocytic Breast Carcinoma in a Man. 61
33062972 2020
2
Oncocytic carcinoma of the breast: frequency, morphology and follow-up. 61
21111455 2011

Variations for Oncocytic Breast Carcinoma

Expression for Oncocytic Breast Carcinoma

Search GEO for disease gene expression data for Oncocytic Breast Carcinoma.

Pathways for Oncocytic Breast Carcinoma

Pathways related to Oncocytic Breast Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.47 PGR KRT14 ESR1
2
Show member pathways
11.17 PGR ESR1 ERBB2
3
Show member pathways
10.92 ESR1 AR
4
Show member pathways
10.75 PGR ESR1 AR

GO Terms for Oncocytic Breast Carcinoma

Cellular components related to Oncocytic Breast Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleus GO:0005634 9.17 PIP PGR KRT7 KRT14 ESR1 ERBB2

Biological processes related to Oncocytic Breast Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription initiation from RNA polymerase II promoter GO:0006367 9.5 PGR ESR1 AR
2 intracellular receptor signaling pathway GO:0030522 9.43 ESR1 AR
3 steroid hormone mediated signaling pathway GO:0043401 9.4 PGR ESR1
4 intracellular estrogen receptor signaling pathway GO:0030520 9.37 ESR1 AR
5 cellular response to estrogen stimulus GO:0071391 9.26 ESR1 AR
6 mammary gland alveolus development GO:0060749 9.16 ESR1 AR
7 tertiary branching involved in mammary gland duct morphogenesis GO:0060748 8.96 PGR AR
8 intracellular steroid hormone receptor signaling pathway GO:0030518 8.8 PGR ESR1 AR

Molecular functions related to Oncocytic Breast Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lipid binding GO:0008289 9.54 PGR ESR1 AR
2 ATPase binding GO:0051117 9.43 PGR ESR1 AR
3 steroid hormone receptor activity GO:0003707 9.32 PGR ESR1
4 RNA polymerase II transcription coactivator binding GO:0001225 9.16 PGR AR
5 nuclear receptor activity GO:0004879 9.13 PGR ESR1 AR
6 steroid binding GO:0005496 8.8 PGR ESR1 AR

Sources for Oncocytic Breast Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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