MCID: ONC001
MIFTS: 31

Oncocytic Breast Carcinoma

Categories: Cancer diseases

Aliases & Classifications for Oncocytic Breast Carcinoma

MalaCards integrated aliases for Oncocytic Breast Carcinoma:

Name: Oncocytic Breast Carcinoma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:6585
NCIt 50 C40366
UMLS 73 C1518574

Summaries for Oncocytic Breast Carcinoma

Disease Ontology : 12 A breast adenocarcinoma that is characterized by abundant eosinophilic cytoplasm due to large numbers of mitochondria.

MalaCards based summary : Oncocytic Breast Carcinoma is related to breast adenomyoepithelioma and large cell acanthoma, and has symptoms including pain An important gene associated with Oncocytic Breast Carcinoma is KRT14 (Keratin 14), and among its related pathways/superpathways are Circadian entrainment and Integrated Breast Cancer Pathway. Affiliated tissues include breast, lung and kidney, and related phenotypes are cellular and endocrine/exocrine gland

Related Diseases for Oncocytic Breast Carcinoma

Diseases related to Oncocytic Breast Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 161)
# Related Disease Score Top Affiliating Genes
1 breast adenomyoepithelioma 10.2 KRT14 KRT7
2 large cell acanthoma 10.2 KRT14 KRT7
3 apocrine sweat gland neoplasm 10.2 KRT14 KRT7
4 spiradenoma 10.2 KRT14 KRT7
5 brooke-spiegler syndrome 10.2 KRT14 KRT7
6 breast myoepithelial neoplasm 10.2 KRT14 KRT7
7 lipoadenoma 10.2 KRT14 KRT7
8 epithelial-myoepithelial carcinoma 10.2 KRT14 KRT7
9 pregnancy adenoma 10.2 KRT14 KRT7
10 vulvar sarcoma 10.2 AR KRT7
11 meibomian cyst 10.1 AR KRT7
12 intraneural perineurioma 10.1 KRT14 KRT7
13 eccrine papillary adenocarcinoma 10.1 KRT7 PGR
14 papillary adenocarcinoma 10.1 KRT7 PGR
15 tonsil cancer 10.1 KRT14 KRT7
16 ceruminoma 10.1 KRT7 PIP
17 endosalpingiosis 10.1 KRT7 PGR
18 large intestine adenocarcinoma 10.1 KRT7 PIP
19 infiltrative basal cell carcinoma 10.1 AR KRT7
20 cutaneous adenocystic carcinoma 10.1 KRT7 PIP
21 nodular hidradenoma 10.1 KRT7 PIP
22 benign metastasizing leiomyoma 10.1 KRT7 PGR
23 vulval paget's disease 10.1 KRT7 PIP
24 pancreatic serous cystadenoma 10.1 KRT7 PGR
25 cystadenoma 10.1 KRT7 PGR
26 white sponge nevus 1 10.1 KRT14 KRT7
27 papillary serous adenocarcinoma 10.1 KRT7 PGR
28 vulva adenocarcinoma 10.1 KRT7 PIP
29 carcinosarcoma 10.1 KRT7 PGR
30 bartholin's duct cyst 10.1 AR PIP
31 dermoid cyst 10.1 KRT7 PGR
32 sertoli-leydig cell tumor 10.1 KRT7 PGR
33 sclerosing hemangioma 10.1 KRT7 PGR
34 primary cutaneous amyloidosis 10.1 KRT14 KRT7
35 cystitis cystica 10.1 AR KRT7
36 breast secretory carcinoma 10.1 KRT7 PGR
37 mucinous adenofibroma 10.1 ESR1 KRT7
38 pancreatic mucinous cystadenoma 10.1 KRT7 PGR
39 mixed cell type cancer 10.1 KRT7 PGR
40 endocervical carcinoma 10.1 ESR1 KRT7
41 postmenopausal atrophic vaginitis 10.1 AR ESR1
42 vaginitis 10.1 AR ESR1
43 gastric signet ring cell adenocarcinoma 10.1 PGR PIP
44 leiomyomatosis 10.1 ESR1 PGR
45 myoma 10.1 ESR1 PGR
46 vestibular gland benign neoplasm 10.1 ESR1 PGR
47 bartholin's gland adenoma 10.1 ESR1 PGR
48 vulvar syringoma 10.1 ESR1 PGR
49 glassy cell carcinoma of the cervix 10.1 ESR1 PGR
50 lung leiomyoma 10.1 ESR1 PGR

Graphical network of the top 20 diseases related to Oncocytic Breast Carcinoma:



Diseases related to Oncocytic Breast Carcinoma

Symptoms & Phenotypes for Oncocytic Breast Carcinoma

UMLS symptoms related to Oncocytic Breast Carcinoma:


pain

MGI Mouse Phenotypes related to Oncocytic Breast Carcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10 AR EGFR ESR1 KRT14 KRT7 PGR
2 endocrine/exocrine gland MP:0005379 9.88 AR EGFR ESR1 KRT14 PGR PIP
3 hematopoietic system MP:0005397 9.85 AR EGFR ESR1 KRT14 PGR PIP
4 digestive/alimentary MP:0005381 9.83 AR EGFR ESR1 KRT14 PIP
5 immune system MP:0005387 9.8 AR EGFR ESR1 KRT14 PGR PIP
6 adipose tissue MP:0005375 9.78 AR EGFR ESR1 KRT14
7 integument MP:0010771 9.65 AR EGFR ESR1 KRT14 PGR
8 limbs/digits/tail MP:0005371 9.46 AR EGFR ESR1 PGR
9 neoplasm MP:0002006 9.35 AR EGFR ESR1 KRT14 PGR
10 reproductive system MP:0005389 9.1 AR EGFR ESR1 KRT14 PGR PIP

Drugs & Therapeutics for Oncocytic Breast Carcinoma

Search Clinical Trials , NIH Clinical Center for Oncocytic Breast Carcinoma

Genetic Tests for Oncocytic Breast Carcinoma

Anatomical Context for Oncocytic Breast Carcinoma

MalaCards organs/tissues related to Oncocytic Breast Carcinoma:

41
Breast, Lung, Kidney, Bone, Colon, Ovary, Smooth Muscle

Publications for Oncocytic Breast Carcinoma

Variations for Oncocytic Breast Carcinoma

Expression for Oncocytic Breast Carcinoma

Search GEO for disease gene expression data for Oncocytic Breast Carcinoma.

Pathways for Oncocytic Breast Carcinoma

GO Terms for Oncocytic Breast Carcinoma

Cellular components related to Oncocytic Breast Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleus GO:0005634 9.17 AR EGFR ESR1 KRT14 KRT7 PGR

Biological processes related to Oncocytic Breast Carcinoma according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription by RNA polymerase II GO:0045944 9.8 AR EGFR ESR1 PGR
2 transcription, DNA-templated GO:0006351 9.54 AR ESR1 PGR
3 transcription initiation from RNA polymerase II promoter GO:0006367 9.5 AR ESR1 PGR
4 positive regulation of fibroblast proliferation GO:0048146 9.48 EGFR ESR1
5 intracellular receptor signaling pathway GO:0030522 9.46 AR ESR1
6 cellular response to estradiol stimulus GO:0071392 9.43 EGFR ESR1
7 positive regulation of phosphorylation GO:0042327 9.4 AR EGFR
8 mammary gland alveolus development GO:0060749 9.26 AR ESR1
9 morphogenesis of an epithelial fold GO:0060571 9.16 AR EGFR
10 steroid hormone mediated signaling pathway GO:0043401 9.13 AR ESR1 PGR
11 tertiary branching involved in mammary gland duct morphogenesis GO:0060748 8.62 AR PGR

Molecular functions related to Oncocytic Breast Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chromatin binding GO:0003682 9.63 AR EGFR ESR1
2 enzyme binding GO:0019899 9.62 AR EGFR ESR1 PGR
3 proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001077 9.61 AR ESR1 PGR
4 lipid binding GO:0008289 9.58 AR ESR1 PGR
5 phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 9.48 EGFR ESR1
6 ATPase binding GO:0051117 9.43 AR ESR1 PGR
7 nitric-oxide synthase regulator activity GO:0030235 9.37 EGFR ESR1
8 steroid hormone receptor activity GO:0003707 9.33 AR ESR1 PGR
9 nuclear receptor activity GO:0004879 9.13 AR ESR1 PGR
10 steroid binding GO:0005496 8.8 AR ESR1 PGR

Sources for Oncocytic Breast Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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