MCID: ONC001
MIFTS: 26

Oncocytic Breast Carcinoma

Categories: Cancer diseases

Aliases & Classifications for Oncocytic Breast Carcinoma

MalaCards integrated aliases for Oncocytic Breast Carcinoma:

Name: Oncocytic Breast Carcinoma 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:6585
NCIt 51 C40366
UMLS 74 C1518574

Summaries for Oncocytic Breast Carcinoma

Disease Ontology : 12 A breast adenocarcinoma that is characterized by abundant eosinophilic cytoplasm due to large numbers of mitochondria.

MalaCards based summary : Oncocytic Breast Carcinoma is related to craniopharyngioma and benign breast adenomyoepithelioma, and has symptoms including pain An important gene associated with Oncocytic Breast Carcinoma is KRT14 (Keratin 14), and among its related pathways/superpathways are Signaling by ERBB4 and FOXA1 transcription factor network. Affiliated tissues include breast, and related phenotypes are cellular and endocrine/exocrine gland

Related Diseases for Oncocytic Breast Carcinoma

Diseases related to Oncocytic Breast Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 164)
# Related Disease Score Top Affiliating Genes
1 craniopharyngioma 10.3 KRT14 KRT7
2 benign breast adenomyoepithelioma 10.3 KRT14 KRT7
3 breast adenomyoepithelioma 10.3 KRT14 KRT7
4 large cell acanthoma 10.3 KRT14 KRT7
5 apocrine sweat gland neoplasm 10.3 KRT14 KRT7
6 spiradenoma 10.3 KRT14 KRT7
7 brooke-spiegler syndrome 10.2 KRT14 KRT7
8 breast myoepithelial neoplasm 10.2 KRT14 KRT7
9 lipoadenoma 10.2 KRT14 KRT7
10 vulvar sarcoma 10.2 AR KRT7
11 epithelial-myoepithelial carcinoma 10.2 KRT14 KRT7
12 pregnancy adenoma 10.2 KRT14 KRT7
13 basaloid squamous cell carcinoma 10.2 KRT14 KRT7
14 meibomian cyst 10.2 AR KRT7
15 eccrine papillary adenocarcinoma 10.2 KRT7 PGR
16 ceruminoma 10.2 KRT7 PIP
17 endosalpingiosis 10.2 KRT7 PGR
18 large intestine adenocarcinoma 10.2 KRT7 PIP
19 intraneural perineurioma 10.2 KRT14 KRT7
20 cutaneous adenocystic carcinoma 10.2 KRT7 PIP
21 nodular hidradenoma 10.2 KRT7 PIP
22 benign metastasizing leiomyoma 10.2 KRT7 PGR
23 pancreatic serous cystadenoma 10.2 KRT7 PGR
24 cystadenoma 10.2 KRT7 PGR
25 infiltrative basal cell carcinoma 10.2 AR KRT7
26 papillary serous adenocarcinoma 10.2 KRT7 PGR
27 bartholin's duct cyst 10.2 AR PIP
28 white sponge nevus 1 10.2 KRT14 KRT7
29 dermoid cyst 10.1 KRT7 PGR
30 oropharynx cancer 10.1 KRT14 KRT7
31 sertoli-leydig cell tumor 10.1 KRT7 PGR
32 sclerosing hemangioma 10.1 KRT7 PGR
33 mucinous adenofibroma 10.1 ESR1 KRT7
34 cystitis cystica 10.1 AR KRT7
35 pancreatic mucinous cystadenoma 10.1 KRT7 PGR
36 endocervical carcinoma 10.1 ESR1 KRT7
37 postmenopausal atrophic vaginitis 10.1 AR ESR1
38 vaginitis 10.1 AR ESR1
39 leiomyomatosis 10.1 ESR1 PGR
40 myoma 10.1 ESR1 PGR
41 primary cutaneous amyloidosis 10.1 KRT14 KRT7
42 gastric signet ring cell adenocarcinoma 10.1 PGR PIP
43 vestibular gland benign neoplasm 10.1 ESR1 PGR
44 bartholin's gland adenoma 10.1 ESR1 PGR
45 vulvar syringoma 10.1 ESR1 PGR
46 lung leiomyoma 10.1 ESR1 PGR
47 vulvar benign neoplasm 10.1 ESR1 PGR
48 trigonitis 10.1 ESR1 PGR
49 vulvar leiomyoma 10.1 ESR1 PGR
50 bartholin's gland benign neoplasm 10.1 ESR1 PGR

Graphical network of the top 20 diseases related to Oncocytic Breast Carcinoma:



Diseases related to Oncocytic Breast Carcinoma

Symptoms & Phenotypes for Oncocytic Breast Carcinoma

UMLS symptoms related to Oncocytic Breast Carcinoma:


pain

MGI Mouse Phenotypes related to Oncocytic Breast Carcinoma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.95 AR ERBB2 ESR1 KRT14 KRT7 PGR
2 endocrine/exocrine gland MP:0005379 9.8 AR ERBB2 ESR1 KRT14 PGR PIP
3 digestive/alimentary MP:0005381 9.77 AR ERBB2 ESR1 KRT14 PIP
4 integument MP:0010771 9.65 AR ERBB2 ESR1 KRT14 PGR
5 limbs/digits/tail MP:0005371 9.46 AR ERBB2 ESR1 PGR
6 neoplasm MP:0002006 9.35 AR ERBB2 ESR1 KRT14 PGR
7 reproductive system MP:0005389 9.1 AR ERBB2 ESR1 KRT14 PGR PIP

Drugs & Therapeutics for Oncocytic Breast Carcinoma

Search Clinical Trials , NIH Clinical Center for Oncocytic Breast Carcinoma

Genetic Tests for Oncocytic Breast Carcinoma

Anatomical Context for Oncocytic Breast Carcinoma

MalaCards organs/tissues related to Oncocytic Breast Carcinoma:

42
Breast

Publications for Oncocytic Breast Carcinoma

Variations for Oncocytic Breast Carcinoma

Expression for Oncocytic Breast Carcinoma

Search GEO for disease gene expression data for Oncocytic Breast Carcinoma.

Pathways for Oncocytic Breast Carcinoma

Pathways related to Oncocytic Breast Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.17 ERBB2 ESR1 PGR
2
Show member pathways
10.82 AR ESR1
3
Show member pathways
10.75 AR ESR1 PGR

GO Terms for Oncocytic Breast Carcinoma

Cellular components related to Oncocytic Breast Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleus GO:0005634 9.17 AR ERBB2 ESR1 KRT14 KRT7 PGR

Biological processes related to Oncocytic Breast Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.61 AR ERBB2 PIP
2 transcription initiation from RNA polymerase II promoter GO:0006367 9.5 AR ESR1 PGR
3 intracellular receptor signaling pathway GO:0030522 9.4 AR ESR1
4 transcription, DNA-templated GO:0006351 9.37 AR ESR1
5 mammary gland alveolus development GO:0060749 9.26 AR ESR1
6 steroid hormone mediated signaling pathway GO:0043401 9.13 AR ESR1 PGR
7 positive regulation of transcription by RNA polymerase III GO:0045945 8.85 AR
8 tertiary branching involved in mammary gland duct morphogenesis GO:0060748 8.62 AR PGR

Molecular functions related to Oncocytic Breast Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 enzyme binding GO:0019899 9.58 AR ESR1 PGR
2 lipid binding GO:0008289 9.54 AR ESR1 PGR
3 protein dimerization activity GO:0046983 9.5 AR ERBB2 PIP
4 phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 9.43 ERBB2 ESR1
5 ATPase binding GO:0051117 9.43 AR ESR1 PGR
6 steroid hormone receptor activity GO:0003707 9.33 AR ESR1 PGR
7 nuclear receptor activity GO:0004879 9.13 AR ESR1 PGR
8 steroid binding GO:0005496 8.8 AR ESR1 PGR

Sources for Oncocytic Breast Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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