MCID: OPH001
MIFTS: 32

Ophthalmomyiasis

Categories: Infectious diseases, Neuronal diseases

Aliases & Classifications for Ophthalmomyiasis

MalaCards integrated aliases for Ophthalmomyiasis:

Name: Ophthalmomyiasis 12 15
Ocular Myiasis 71 32

Classifications:



External Ids:

Disease Ontology 12 DOID:0050268
ICD10 32 B87.2
UMLS 71 C0027034

Summaries for Ophthalmomyiasis

Disease Ontology : 12 A myiasis that involves parasitic infestation of Oestrus ovis larvae in the eye causing severe irritation, edema, and pain.

MalaCards based summary : Ophthalmomyiasis, also known as ocular myiasis, is related to myiasis and iridocyclitis. An important gene associated with Ophthalmomyiasis is DYNC1H1 (Dynein Cytoplasmic 1 Heavy Chain 1), and among its related pathways/superpathways are Pathways of neurodegeneration - multiple diseases and Prion disease. Affiliated tissues include eye and retina, and related phenotypes are homeostasis/metabolism and muscle

Wikipedia : 74 Myiasis is the parasitic infestation of the body of a live animal by fly larvae (maggots) which grow... more...

Related Diseases for Ophthalmomyiasis

Diseases related to Ophthalmomyiasis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 128)
# Related Disease Score Top Affiliating Genes
1 myiasis 31.3 MT-CYB MT-CO1 DYNC1H1
2 iridocyclitis 30.6 RBP3 CD4
3 neuroretinitis 30.2 SAG CD4
4 thelaziasis 30.1 MT-CYB MT-CO1
5 panuveitis 30.0 SAG RBP3 CD4
6 panophthalmitis 30.0 SAG CD4
7 chorioretinitis 29.8 SAG RBP3 CD4
8 amyotrophic lateral sclerosis 1 28.7 TARDBP SOD1 PRKN MT-CO1 LRRK2 DYNC1H1
9 conjunctivitis 10.6
10 uveitis 10.4
11 oesophagostomiasis 10.3 MT-CYB MT-CO1
12 sparganosis 10.3 MT-CYB MT-CO1
13 pediculus humanus corporis infestation 10.3 MT-CYB MT-CO1
14 distal hereditary motor neuronopathy type 7 10.3 TARDBP DYNC1H1
15 cellulitis 10.3
16 neuronopathy, distal hereditary motor, type viib 10.3 TARDBP DYNC1H1
17 baylisascariasis 10.3 MT-CYB MT-CO1
18 mitochondrial myopathy, infantile, transient 10.3 MT-CYB MT-CO1
19 cerebellar medulloblastoma 10.3 SAG RBP3
20 plasmodium ovale malaria 10.2 MT-CYB CYP2D6
21 cystoisosporiasis 10.2 MT-CO1 CD4
22 purulent endophthalmitis 10.2 RBP3 CD4
23 parkinson disease 10 10.2 PRKN LRRK2
24 color agnosia 10.2 PRKN LRRK2
25 keratitis, hereditary 10.2
26 retinal detachment 10.2
27 yemenite deaf-blind hypopigmentation syndrome 10.2
28 cyclosporiasis 10.2 MT-CYB CD4
29 bacillary angiomatosis 10.2 MT-CYB CD4
30 hypopyon 10.2 RBP3 CD4
31 amelogenesis imperfecta, type iv 10.2 MT-CYB MT-CO1
32 mite infestation 10.1 MT-CO1 CD4
33 radial nerve lesion 10.1 PRKN LRRK2
34 chronic meningitis 10.1 MT-CO1 CD4
35 scleral disease 10.1 RBP3 CD4
36 parkinson disease 21 10.1 PRKN LRRK2
37 polyradiculopathy 10.1 CD4 AKR1B1
38 acute conjunctivitis 10.1
39 orbital cellulitis 10.1
40 superficial mycosis 10.1 MT-CYB CD4
41 iritis 10.1 RBP3 CD4
42 tick infestation 10.1 MT-CO1 CD4
43 mucocutaneous leishmaniasis 10.1 MT-CYB CD4
44 ulnar nerve lesion 10.1 PRKN LRRK2
45 bartonellosis 10.1 MT-CYB MT-CO1 CD4
46 taeniasis 10.1 MT-CYB MT-CO1 CD4
47 babesiosis 10.1 MT-CYB MT-CO1 CD4
48 parasitic ectoparasitic infectious disease 10.1 MT-CYB MT-CO1 CD4
49 epidemic typhus 10.1 MT-CYB MT-CO1 CD4
50 posterior uveitis 10.1

Graphical network of the top 20 diseases related to Ophthalmomyiasis:



Diseases related to Ophthalmomyiasis

Symptoms & Phenotypes for Ophthalmomyiasis

MGI Mouse Phenotypes related to Ophthalmomyiasis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.77 AKR1B1 CD4 DYNC1H1 EXO1 GSK3B LPL
2 muscle MP:0005369 9.17 DYNC1H1 GSK3B LPL MT-CO1 PRKN SOD1

Drugs & Therapeutics for Ophthalmomyiasis

Search Clinical Trials , NIH Clinical Center for Ophthalmomyiasis

Genetic Tests for Ophthalmomyiasis

Anatomical Context for Ophthalmomyiasis

MalaCards organs/tissues related to Ophthalmomyiasis:

40
Eye, Retina

Publications for Ophthalmomyiasis

Articles related to Ophthalmomyiasis:

(show top 50) (show all 348)
# Title Authors PMID Year
1
Ophthalmomyiasis Externa: A Case Report. 61
33269574 2020
2
Cryptic Myiasis by Chrysomya bezziana: A Case Report and Literature Review. 61
33389940 2020
3
External ophthalmomyiasis by Oestrus ovis larvae. 61
31943076 2020
4
[Negleged corneal ophthalmomyiasis]. 61
32620416 2020
5
Ocular myiasis secondary to Dermatobia hominis. 61
32067696 2020
6
Phthiriasis palpebrarum, thelaziasis, and ophthalmomyiasis. 61
32447120 2020
7
External ophthalmomyiasis in a neonate masquerading as an orbital cellulitis. 61
32317476 2020
8
Concurrent ophthalmomyiasis externa and aural myiasis: A case report in an urban hospital in the United States. 61
32021944 2020
9
Human ophthalmomyiasis caused by Oestrus ovis-first report from Croatia and review on cases from Mediterranean countries. 61
31955262 2020
10
Unusual Case: Ophthalmomyiasis. 61
33206876 2020
11
EXTERNAL OPHTHALMOMYIASIS CAUSED BY OESTRUS OVIS (A CASE REPORT). 61
33126809 2020
12
Ophthalmomyiasis Caused by Chrysomya bezziana after Periocular Carcinoma. 61
31625856 2019
13
"Pacman" invasion of the retina: Two cases of ophthalmomyiasis interna posterior. 61
31249904 2019
14
[Oestrus ovis ophthalmomyiasis at an urban area in Southern Peru]. 61
31859759 2019
15
Post-traumatic intraocular ophthalmomyasis due to Phormia sp. 61
30337097 2019
16
External ophthalmomyiasis due to Oestrus ovis. 61
30777968 2019
17
Massive orbital myiasis arising from nasal myiasis in an Indonesian patient with diabetes. 61
30706000 2019
18
Ophthalmomyiasis externa due to sheep nasal botfly in rural Jamaica. 61
30419775 2019
19
A Case and Review of Ophthalmomyiasis Caused by Oestrus ovis in the Central Valley of California, United States. 61
30947546 2019
20
[External ophthalmomyiasis]. 61
30446342 2018
21
Ocular external myiasis. A series of cases due to larvae Oestrus ovis in Navarra, Spain. 61
30025990 2018
22
Ophthalmomyiasis caused by larvae of the parasite Oestrus ovis. 61
29800329 2018
23
External ophthalmomyiasis due to Dermatobia hominis. A case report. 61
29580757 2018
24
Ocular Myiasis. 61
30090197 2018
25
Ophthalmomyiasis externa: A case report from Alkharj, Saudi Arabia. 61
30224893 2018
26
Ophthalmomyiasis in a case of basal cell carcinoma of eyelid. 61
29866693 2018
27
Ophthalmomyiasis externa due to Oestrus ovis in a traveller returning from Greece. 61
29793045 2018
28
External ophthalmomyiasis caused by Oestrus ovis in east China. 61
29111870 2018
29
External ophthalmomyiasis caused by Oestrus ovis. 61
28778125 2018
30
Orbital ophthalmomyiasis caused by Chrysomya bezziana in Thailand. 61
33601802 2018
31
External ophthalmomyiasis by Oestrus ovis: A case report from Davangere. 61
29403219 2018
32
Facultative myiasis of domestic cats by Sarcophaga argyrostoma (Diptera: Sarcophagidae), Calliphora vicina and Lucilia sericata (Diptera: Calliphoridae) in northern Italy. 61
28803354 2017
33
Ophthalmomyiasis and nasal myiasis by Oestrus ovis in a patient from the Canary Islands with uncommon epidemiological characteristics. 61
26620606 2017
34
Human myiasis caused by the reindeer warble fly, Hypoderma tarandi, case series from Norway, 2011 to 2016. 61
28749332 2017
35
External Ophthalmomyiasis Caused by Lucilia sericata (Diptera: Challiphoride) Larva. 61
28979359 2017
36
A case of ophthalmomyiasis interna in the Pacific Northwest. 61
29260045 2017
37
Ophthalmomyiasis interna masquerading as orbital cellulitis. 61
27810422 2016
38
External ophthalmomyiasis: a case series and review of ophthalmomyiasis in Turkey. 61
26895273 2016
39
External Ophthalmomyiasis Due to Dermatobia hominis Masquerading As Orbital Cellulitis. 61
25226095 2016
40
Ocular myiasis in a glioma: a case report. 61
28478471 2016
41
Spectral-Domain Optical Coherence Tomography, Wide-Field Photography, and Fundus Autofluorescence Correlation of Posterior Ophthalmomyiasis Interna. 61
27434903 2016
42
Ophthalmomyiasis Caused by Sheep Nasal Botfly (Oestrus ovis). 61
27097709 2016
43
Periungual myiasis caused by wohlfahrtia magnifica mimicking an ingrown toenail. 61
27186528 2016
44
[External ophthalmomyiasis in Morocco: About a case in an urban area]. 61
26995078 2016
45
Ophthalmomyiasis Interna. 61
26802704 2016
46
[The first case of Hypoderma tarandi-associated human myiasis in Greenland]. 61
26750192 2016
47
Unilateral conjunctivitis of unique etiology: A case report from Eastern India. 61
27003982 2016
48
Extreme Ophthalmomyiasis externa with simultaneous facial and scalp involvement. 61
28242894 2016
49
ENHANCED DEPTH IMAGING FEATURES OF A CHOROIDAL MACROVESSEL. 61
26035135 2016
50
External ophthalmomyiasis. A case report from Spain. 61
26456485 2015

Variations for Ophthalmomyiasis

Expression for Ophthalmomyiasis

Search GEO for disease gene expression data for Ophthalmomyiasis.

Pathways for Ophthalmomyiasis

Pathways related to Ophthalmomyiasis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.94 TARDBP SOD1 PRKN MT-CYB MT-CO1 LRRK2
2
Show member pathways
12.15 SOD1 PRKN MT-CYB MT-CO1 LRRK2 GSK3B
3 11.63 TARDBP SOD1 SAG PRKN LRRK2 GSK3B

GO Terms for Ophthalmomyiasis

Cellular components related to Ophthalmomyiasis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 mitochondrion GO:0005739 9.5 SOD1 PRKN MT-CYB MT-CO1 LRRK2 GSK3B
2 mitochondrial respiratory chain complex III GO:0005750 9.16 MT-CYB MT-CO1
3 Wnt signalosome GO:1990909 8.62 LRRK2 GSK3B

Biological processes related to Ophthalmomyiasis according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.97 SOD1 MT-CYB MT-CO1 CYP2D6 AKR1B1
2 regulation of protein stability GO:0031647 9.71 TARDBP PRKN LRRK2
3 negative regulation of protein phosphorylation GO:0001933 9.69 TARDBP PRKN LRRK2
4 positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 9.65 PRKN LRRK2 GSK3B
5 positive regulation of protein binding GO:0032092 9.63 PRKN LRRK2 GSK3B
6 retinoid metabolic process GO:0001523 9.58 RBP3 LPL AKR1B1
7 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway GO:1902236 9.57 PRKN LRRK2
8 respiratory electron transport chain GO:0022904 9.56 MT-CYB MT-CO1
9 cellular response to dopamine GO:1903351 9.55 PRKN LRRK2
10 negative regulation of neuron death GO:1901215 9.54 PRKN LRRK2 GSK3B
11 retrograde axonal transport GO:0008090 9.52 SOD1 DYNC1H1
12 cellular response to manganese ion GO:0071287 9.49 PRKN LRRK2
13 protein localization to mitochondrion GO:0070585 9.43 PRKN LRRK2
14 norepinephrine metabolic process GO:0042415 9.32 PRKN AKR1B1
15 electron transport coupled proton transport GO:0015990 9.26 MT-CYB MT-CO1
16 response to oxidative stress GO:0006979 9.26 SOD1 PRKN MT-CO1 LRRK2
17 regulation of synaptic vesicle transport GO:1902803 9.16 PRKN LRRK2
18 response to copper ion GO:0046688 8.8 SOD1 MT-CYB MT-CO1

Sources for Ophthalmomyiasis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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