ODS1
MCID: OPD004
MIFTS: 11

Opioid Dependence 1 (ODS1)

Aliases & Classifications for Opioid Dependence 1

MalaCards integrated aliases for Opioid Dependence 1:

Name: Opioid Dependence 1 57 29 6
Opioid Dependence, Susceptibility to, 1 57 13
Dependence, Opioid, Susceptibility to 1 39
Ods1 57

External Ids:

OMIM® 57 610064

Summaries for Opioid Dependence 1

MalaCards based summary : Opioid Dependence 1, also known as opioid dependence, susceptibility to, 1, is related to opiate dependence. An important gene associated with Opioid Dependence 1 is ODS1 (Opioid Dependence, Susceptibility To, 1).

More information from OMIM: 610064

Related Diseases for Opioid Dependence 1

Diseases related to Opioid Dependence 1 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 opiate dependence 9.5 OPRM1 ODS1

Symptoms & Phenotypes for Opioid Dependence 1

Clinical features from OMIM®:

610064 (Updated 20-May-2021)

Drugs & Therapeutics for Opioid Dependence 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Neurobiology of Opioid Dependence: 1 Withdrawn NCT00000192 Phase 2 Lamotrigine

Search NIH Clinical Center for Opioid Dependence 1

Genetic Tests for Opioid Dependence 1

Genetic tests related to Opioid Dependence 1:

# Genetic test Affiliating Genes
1 Opioid Dependence 1 29

Anatomical Context for Opioid Dependence 1

Publications for Opioid Dependence 1

Articles related to Opioid Dependence 1:

# Title Authors PMID Year
1
ABCB1 (MDR1) genetic variants are associated with methadone doses required for effective treatment of heroin dependence. 57
18424454 2008
2
Genomewide linkage scan for opioid dependence and related traits. 57
16642432 2006
3
Association of specific haplotypes of D2 dopamine receptor gene with vulnerability to heroin dependence in 2 distinct populations. 57
15184239 2004
4
Genetic influences on DSM-III-R drug abuse and dependence: a study of 3,372 twin pairs. 57
8886164 1996
5
Emergency department-initiated buprenorphine/naloxone treatment for opioid dependence: a randomized clinical trial. 61
25919527 2015

Variations for Opioid Dependence 1

ClinVar genetic disease variations for Opioid Dependence 1:

6
# Gene Name Type Significance ClinVarId dbSNP ID Position
1 OPRM1 NM_001145280.3(OPRM1):c.-11+28644A>G SNV Uncertain significance 9538 rs1799971 GRCh37: 6:154360797-154360797
GRCh38: 6:154039662-154039662

Expression for Opioid Dependence 1

Search GEO for disease gene expression data for Opioid Dependence 1.

Pathways for Opioid Dependence 1

GO Terms for Opioid Dependence 1

Sources for Opioid Dependence 1

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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