MCID: OPP002
MIFTS: 36

Opportunistic Mycosis

Categories: Infectious diseases

Aliases & Classifications for Opportunistic Mycosis

MalaCards integrated aliases for Opportunistic Mycosis:

Name: Opportunistic Mycosis 12 15 74
Opportunistic Systemic Mycoses 12
Opportunistic Mycoses 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2473
ICD9CM 36 118
SNOMED-CT 69 78999002
ICD10 34 B48.7
UMLS 74 C0029119

Summaries for Opportunistic Mycosis

Disease Ontology : 12 A systemic mycosis that results in fungal infection located in human body of immunocompromised individuals, has material basis in Fungi. The organisms invade via the respiratory tract, alimentary tract, or intravascular devices.

MalaCards based summary : Opportunistic Mycosis, also known as opportunistic systemic mycoses, is related to trichosporonosis and cryptococcosis. An important gene associated with Opportunistic Mycosis is RHNO1 (RAD9-HUS1-RAD1 Interacting Nuclear Orphan 1), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. Affiliated tissues include human body of immunocompromised individuals, and related phenotypes are hematopoietic system and immune system

Related Diseases for Opportunistic Mycosis

Diseases related to Opportunistic Mycosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 197)
# Related Disease Score Top Affiliating Genes
1 trichosporonosis 32.3 IFNG IL17A TNF
2 cryptococcosis 32.0 CARD9 IFNG IL4 ST5
3 aspergillosis 31.4 CLEC7A IFNG IL10 IL4 TLR2 TNF
4 candidiasis 30.4 AIRE CARD9 CLEC7A IFNG IL10 IL17A
5 immunodysregulation, polyendocrinopathy, and enteropathy, x-linked 30.2 AIRE IFNG IL10 IL4
6 penicilliosis 11.2
7 fusariosis 11.2
8 pneumocystosis 11.2
9 geotrichosis 11.2
10 microsporidiosis 11.2
11 maple bark strippers' lung 11.2
12 mucormycosis 11.2
13 subcutaneous mycosis 10.6 CARD9 CLEC7A
14 tinea capitis 10.5 CARD9 ST5
15 miller fisher syndrome 10.5 ST5 TNF
16 chronic beryllium disease 10.5 IFNG TNF
17 sporotrichosis 10.5 IFNG IL10
18 parasitic ichthyosporea infectious disease 10.4 IL4 RHNO1
19 rhinosporidiosis 10.4 IL4 RHNO1
20 transient hypogammaglobulinemia 10.4 IL10 TNF
21 candidiasis, familial, 2 10.4 CARD9 CLEC7A
22 punctate inner choroidopathy 10.3 IL10 TNF
23 common wart 10.3 CLEC6A CLEC7A
24 cephalosporin allergy 10.3 IFNG IL10
25 scedosporiosis 10.3
26 campylobacteriosis 10.3 IFNG ST5 STAT1
27 central nervous system vasculitis 10.3 IFNG IL17A TNF
28 palladium allergic contact dermatitis 10.3 IL10 IL17A
29 chromoblastomycosis 10.3 CARD9 CLEC7A IL4
30 periodontal disease 10.3 IL17A TLR2 TNF
31 langerhans cell histiocytosis 10.3 CD101 IFNG IL17A
32 staphylococcal toxic shock syndrome 10.3 IFNG TNF
33 haemophilus influenzae 10.3 CLEC7A TLR2 TNF
34 myositis fibrosa 10.3 IFNG IL17A TLR2
35 invasive aspergillosis 10.3 CLEC7A IFNG TLR2
36 mycobacterium abscessus 10.3 CLEC7A TLR2 TNF
37 polyradiculoneuropathy 10.3 IFNG IL10 IL17A
38 alopecia areata 10.3 AIRE IFNG TNF
39 hemorrhagic fever 10.2 IFNG IL10 TNF
40 autoimmune disease of eyes, ear, nose and throat 10.2 IL10 IL17A TNF
41 transverse myelitis 10.2 IL10 IL17A TNF
42 chronic graft versus host disease 10.2 IFNG IL10 TNF
43 clonorchiasis 10.2 IFNG IL10 TNF
44 neurosyphilis 10.2 IL10 IL17A TLR2
45 panuveitis 10.2 IL10 IL17A TNF
46 intermediate uveitis 10.2 IFNG IL10 TNF
47 tropical spastic paraparesis 10.2 IFNG IL10 IL17A
48 spotted fever 10.2 IFNG IL10 TNF
49 aseptic meningitis 10.2 IFNG IL10 TNF
50 autoimmune myocarditis 10.2 IFNG TNF

Graphical network of the top 20 diseases related to Opportunistic Mycosis:



Diseases related to Opportunistic Mycosis

Symptoms & Phenotypes for Opportunistic Mycosis

MGI Mouse Phenotypes related to Opportunistic Mycosis:

47 (show all 13)
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.38 AIRE CARD9 CCR6 CD101 CLEC6A CLEC7A
2 immune system MP:0005387 10.34 AIRE CARD9 CCR6 CD101 CLEC6A CLEC7A
3 homeostasis/metabolism MP:0005376 10.27 AIRE CARD9 CCR6 CLEC7A HHAT IFNG
4 digestive/alimentary MP:0005381 10.25 AIRE CLEC7A HHAT IFNG IL10 IL17A
5 mortality/aging MP:0010768 10.21 AIRE CLEC6A CLEC7A HHAT IFNG IL10
6 endocrine/exocrine gland MP:0005379 10.15 AIRE HHAT IFNG IL10 IL17A IL4
7 craniofacial MP:0005382 10.07 HHAT IFNG IL10 IL17A IL17F IL4
8 liver/biliary system MP:0005370 9.95 AIRE IFNG IL10 IL4 STAT1 TLR2
9 no phenotypic analysis MP:0003012 9.91 AIRE CLEC6A IFNG IL10 IL17A IL17RA
10 respiratory system MP:0005388 9.9 AIRE CLEC7A HHAT IFNG IL10 IL17A
11 neoplasm MP:0002006 9.87 AIRE IFNG IL10 IL17RA STAT1 TLR2
12 skeleton MP:0005390 9.61 HHAT IFNG IL10 IL17A IL17F IL4
13 vision/eye MP:0005391 9.23 AIRE HHAT IFNG IL10 IL4 KIDINS220

Drugs & Therapeutics for Opportunistic Mycosis

Search Clinical Trials , NIH Clinical Center for Opportunistic Mycosis

Genetic Tests for Opportunistic Mycosis

Anatomical Context for Opportunistic Mycosis

The Foundational Model of Anatomy Ontology organs/tissues related to Opportunistic Mycosis:

20
Human Body Of Immunocompromised Individuals

Publications for Opportunistic Mycosis

Articles related to Opportunistic Mycosis:

# Title Authors Year
1
Experimental Trichosporon infection in persistently granulocytopenic rabbits: implications for pathogenesis, diagnosis, and treatment of an emerging opportunistic mycosis. ( 1535092 )
1992
2
Opportunistic systemic mycoses and the critical care patient. ( 6554147 )
1983
3
Treatment of opportunistic systemic mycoses. ( 373079 )
1978

Variations for Opportunistic Mycosis

Expression for Opportunistic Mycosis

Search GEO for disease gene expression data for Opportunistic Mycosis.

Pathways for Opportunistic Mycosis

Pathways related to Opportunistic Mycosis according to GeneCards Suite gene sharing:

(show all 41)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.96 CARD9 CCR6 CD101 CLEC6A CLEC7A IFNG
2
Show member pathways
13.38 CCR6 IL10 IL17A IL17RA IL4 STAT1
3
Show member pathways
13.33 IFNG IL10 IL17A IL17F IL17RA IL4
4
Show member pathways
13.17 CARD9 IFNG IL10 STAT1 TLR2 TNF
5
Show member pathways
12.85 IFNG IL10 IL17A IL4 STAT1 TNF
6
Show member pathways
12.57 IFNG IL10 IL17A IL17F STAT1 TNF
7
Show member pathways
12.56 IFNG IL4 STAT1 TLR2 TNF
8
Show member pathways
12.46 IFNG IL10 IL17A IL17F IL4 STAT1
9
Show member pathways
12.41 IFNG IL10 IL17A IL4 TNF
10 12.37 CARD9 IFNG IL10 IL17A IL4 STAT1
11
Show member pathways
12.35 IFNG IL10 IL4 STAT1
12
Show member pathways
12.25 IFNG IL10 IL17A IL4 STAT1 TNF
13
Show member pathways
12.24 IFNG IL17A IL17F IL17RA IL4 TLR2
14
Show member pathways
12.23 IFNG IL10 IL4 STAT1 TLR2 TNF
15 12.17 IFNG STAT1 TLR2 TNF
16
Show member pathways
12.17 CARD9 CLEC6A CLEC7A IL10 STAT1 TNF
17
Show member pathways
12.16 IFNG IL4 STAT1 TLR2 TNF
18
Show member pathways
12.07 IFNG IL10 IL17A IL4 STAT1
19
Show member pathways
12.02 IFNG IL4 TLR2 TNF
20 11.98 IFNG IL10 IL4 TNF
21 11.95 CARD9 CLEC7A IFNG IL10 STAT1 TLR2
22 11.94 IL10 IL17A IL17F IL4 STAT1 TNF
23 11.87 IFNG IL10 TLR2 TNF
24 11.84 IFNG IL17A TLR2 TNF
25
Show member pathways
11.83 IL17A IL17F IL17RA
26 11.77 IFNG IL4 STAT1
27 11.75 IFNG IL10 IL17RA TNF
28
Show member pathways
11.73 IFNG IL4 TNF
29 11.68 IFNG IL10 IL17A IL4 TNF
30 11.61 IFNG STAT1 TNF
31
Show member pathways
11.61 IFNG IL10 IL17A IL17F STAT1 TLR2
32 11.53 IFNG IL10 TLR2 TNF
33 11.52 IL10 IL4 TNF
34 11.5 IFNG TLR2 TNF
35 11.48 IFNG IL10 IL4
36 11.37 IFNG IL10 TNF
37 11.32 IFNG IL17A IL4 TNF
38 11.26 IFNG IL10 IL4 TNF
39 11.19 IL10 IL17A IL4 TNF
40 11.19 IFNG IL10 IL4
41 11.07 CCR6 CD101 IFNG IL10 IL17A IL4

GO Terms for Opportunistic Mycosis

Biological processes related to Opportunistic Mycosis according to GeneCards Suite gene sharing:

(show all 32)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.93 IFNG IL10 IL17A IL17F IL4 TNF
2 inflammatory response GO:0006954 9.88 CLEC7A IL10 IL17A IL17F TLR2 TNF
3 defense response to Gram-positive bacterium GO:0050830 9.82 CARD9 TLR2 TNF
4 positive regulation of inflammatory response GO:0050729 9.8 IL17RA TLR2 TNF
5 positive regulation of interleukin-6 production GO:0032755 9.79 CARD9 TLR2 TNF
6 cytokine-mediated signaling pathway GO:0019221 9.73 IL10 IL17A IL17F IL4 STAT1 TNF
7 defense response to fungus GO:0050832 9.71 CLEC6A IL17A IL17RA
8 positive regulation of cytokine secretion GO:0050715 9.7 CLEC6A IL10 TNF
9 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.65 IFNG TNF
10 negative regulation of growth of symbiont in host GO:0044130 9.65 IL10 TNF
11 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.65 IL10 TNF
12 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.64 STAT1 TLR2
13 regulation of interferon-gamma-mediated signaling pathway GO:0060334 9.63 IFNG STAT1
14 response to molecule of bacterial origin GO:0002237 9.63 IL10 TLR2
15 endothelial cell apoptotic process GO:0072577 9.62 IL10 TNF
16 humoral immune response GO:0006959 9.62 AIRE CCR6 IFNG TNF
17 positive regulation of MHC class II biosynthetic process GO:0045348 9.61 IL10 IL4
18 positive regulation of osteoclast differentiation GO:0045672 9.61 IFNG IL17A TNF
19 negative regulation of cytokine secretion involved in immune response GO:0002740 9.6 IL10 TNF
20 regulation of isotype switching GO:0045191 9.59 IL10 IL4
21 type 2 immune response GO:0042092 9.58 IL10 IL4
22 fibroblast activation GO:0072537 9.58 IL17A IL17RA
23 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.57 IFNG TNF
24 receptor biosynthetic process GO:0032800 9.56 IL10 TNF
25 regulation of interleukin-6 biosynthetic process GO:0045408 9.55 CARD9 IL17F
26 positive regulation of cytokine production involved in inflammatory response GO:1900017 9.54 IL17A IL17F IL17RA
27 positive regulation of vitamin D biosynthetic process GO:0060557 9.51 IFNG TNF
28 regulation of interleukin-2 biosynthetic process GO:0045076 9.49 CARD9 IL17F
29 interleukin-17-mediated signaling pathway GO:0097400 9.33 IL17A IL17F IL17RA
30 immune response GO:0006955 9.23 AIRE CCR6 IFNG IL10 IL17A IL4
31 positive regulation of interleukin-23 production GO:0032747 9.13 IFNG IL17A IL17RA
32 positive regulation of transcription by RNA polymerase II GO:0045944 10.08 AIRE IL10 IL17A IL17F IL4 STAT1

Molecular functions related to Opportunistic Mycosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.1 IFNG IL10 IL17A IL17F IL4 TNF
2 signaling pattern recognition receptor activity GO:0008329 8.96 CLEC7A TLR2

Sources for Opportunistic Mycosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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