MCID: OPP002
MIFTS: 44

Opportunistic Mycosis

Categories: Infectious diseases

Aliases & Classifications for Opportunistic Mycosis

MalaCards integrated aliases for Opportunistic Mycosis:

Name: Opportunistic Mycosis 12 15 73
Opportunistic Systemic Mycoses 12
Opportunistic Mycoses 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2473
ICD9CM 35 118
SNOMED-CT 68 78999002
ICD10 33 B48.7
UMLS 73 C0029119

Summaries for Opportunistic Mycosis

Disease Ontology : 12 A systemic mycosis that results in fungal infection located in human body of immunocompromised individuals, has material basis in Fungi. The organisms invade via the respiratory tract, alimentary tract, or intravascular devices.

MalaCards based summary : Opportunistic Mycosis, also known as opportunistic systemic mycoses, is related to pneumocystosis and trichosporonosis. An important gene associated with Opportunistic Mycosis is FLNC (Filamin C), and among its related pathways/superpathways are Innate Immune System and Akt Signaling. Affiliated tissues include liver, lung and skin, and related phenotypes are hematopoietic system and homeostasis/metabolism

Related Diseases for Opportunistic Mycosis

Diseases related to Opportunistic Mycosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 217)
# Related Disease Score Top Affiliating Genes
1 pneumocystosis 32.1 TNF FLNC CLEC7A
2 trichosporonosis 32.1 IFNG IL17A TNF
3 penicilliosis 31.8 CDR1 TLR2 TNF
4 cryptococcosis 31.7 TLR9 ST5 PLB1 IL4 IFNG CARD9
5 aspergillosis 31.4 TNF TLR9 TLR2 IL4 IL10 IFNG
6 candidiasis 30.7 STAT1 SKAP2 PLB1 IL17RA IL17A IL10
7 fusariosis 11.2
8 geotrichosis 11.2
9 microsporidiosis 11.2
10 maple bark strippers' lung 11.2
11 mucormycosis 11.2
12 candidiasis, familial, 2 10.4 CLEC7A CARD9
13 tracheitis 10.3 RHNO1 TNF
14 eye lymphoma 10.3 IL10 TLR9
15 miller fisher syndrome 10.3 ST5 TNF
16 parasitic ichthyosporea infectious disease 10.3 IL4 RHNO1
17 rhinosporidiosis 10.3 IL4 RHNO1
18 palladium allergic contact dermatitis 10.3 IL10 IL17A
19 staphylococcal toxic shock syndrome 10.3 IFNG TNF
20 cephalosporin allergy 10.3 IL10 IFNG
21 sporotrichosis 10.3 IFNG IL10
22 familial candidiasis 10.3 IL17RA CARD9
23 b-cell growth factor 10.3 IFNG IL4
24 microscopic polyangiitis 10.3 IL10 TNF
25 multifocal choroiditis 10.3 IL10 TNF
26 scedosporiosis 10.3
27 tinea capitis 10.3 CARD9 FLNC ST5
28 trench fever 10.3 TLR2 TNF
29 idiopathic interstitial pneumonia 10.2 TLR9 IL4 IFNG
30 sezary's disease 10.2 TLR9 IL4 IFNG
31 punctate inner choroidopathy 10.2 TNF IL10
32 chromoblastomycosis 10.2 CARD9 CLEC7A IL4
33 graft-versus-host disease 10.2 TNF IL10 IFNG
34 campylobacteriosis 10.2 IFNG ST5 STAT1
35 acquired immunodeficiency syndrome 10.2 TNF IL10 IFNG
36 fungal meningitis 10.2 FLNC IFNG IL10
37 viral hepatitis 10.2 TLR2 TLR9 TNF
38 mucocutaneous leishmaniasis 10.2 IL10 TLR9 TNF
39 hypersensitivity reaction type iv disease 10.2 TNF TLR9 IFNG
40 periodontal disease 10.2 IL17A TLR2 TNF
41 tetanus 10.2 IFNG IL10 IL4
42 hemorrhagic fever 10.2 IFNG IL10 TNF
43 oral cavity cancer 10.2 IL4 TLR2 TLR9
44 transverse myelitis 10.2 IL10 IL17A TNF
45 autoimmune myocarditis 10.2 IFNG IL4 TNF
46 lacrimal apparatus disease 10.2 TNF TLR9 IL10
47 central nervous system vasculitis 10.2 IFNG IL17A TLR9 TNF
48 conjunctival disease 10.2 TNF RHNO1 IL4
49 chronic graft versus host disease 10.1 IFNG IL10 TNF
50 polyradiculoneuropathy 10.1 IL17A IL10 IFNG

Graphical network of the top 20 diseases related to Opportunistic Mycosis:



Diseases related to Opportunistic Mycosis

Symptoms & Phenotypes for Opportunistic Mycosis

MGI Mouse Phenotypes related to Opportunistic Mycosis:

46 (show all 11)
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.3 AIRE CARD9 CD101 CLEC7A IFNG IL10
2 homeostasis/metabolism MP:0005376 10.28 AIRE CARD9 CLEC7A FLNC HHAT IFNG
3 immune system MP:0005387 10.25 AIRE CARD9 CD101 CLEC7A IFNG IL10
4 digestive/alimentary MP:0005381 10.24 AIRE CLEC7A HHAT IFNG IL10 IL17A
5 endocrine/exocrine gland MP:0005379 10.13 AIRE HHAT IFNG IL10 IL17A IL4
6 mortality/aging MP:0010768 10.07 AIRE CLEC7A FLNC HHAT IFNG IL10
7 integument MP:0010771 9.97 FLNC IFNG IL10 IL17RA IL4 STAT1
8 liver/biliary system MP:0005370 9.87 AIRE IFNG IL10 IL4 STAT1 TLR2
9 neoplasm MP:0002006 9.7 AIRE IFNG IL10 IL17RA STAT1 TLR2
10 no phenotypic analysis MP:0003012 9.5 AIRE IFNG IL10 IL17A IL17RA IL4
11 respiratory system MP:0005388 9.36 AIRE CLEC7A FLNC HHAT IFNG IL10

Drugs & Therapeutics for Opportunistic Mycosis

Search Clinical Trials , NIH Clinical Center for Opportunistic Mycosis

Genetic Tests for Opportunistic Mycosis

Anatomical Context for Opportunistic Mycosis

MalaCards organs/tissues related to Opportunistic Mycosis:

41
Liver, Lung, Skin, Bone, Eye, Thyroid, T Cells

The Foundational Model of Anatomy Ontology organs/tissues related to Opportunistic Mycosis:

19
Human Body Of Immunocompromised Individuals

Publications for Opportunistic Mycosis

Articles related to Opportunistic Mycosis:

# Title Authors Year
1
Experimental Trichosporon infection in persistently granulocytopenic rabbits: implications for pathogenesis, diagnosis, and treatment of an emerging opportunistic mycosis. ( 1535092 )
1992
2
Opportunistic systemic mycoses and the critical care patient. ( 6554147 )
1983
3
Treatment of opportunistic systemic mycoses. ( 373079 )
1978

Variations for Opportunistic Mycosis

Expression for Opportunistic Mycosis

Search GEO for disease gene expression data for Opportunistic Mycosis.

Pathways for Opportunistic Mycosis

Pathways related to Opportunistic Mycosis according to GeneCards Suite gene sharing:

(show all 40)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.01 CARD9 CD101 CLEC7A IFNG IL10 IL17A
2
Show member pathways
13.38 IL10 IL17A IL17RA IL4 STAT1 TLR2
3
Show member pathways
13.33 IFNG IL10 IL17A IL17RA IL4 STAT1
4
Show member pathways
12.98 CARD9 IFNG IL10 STAT1 TLR2 TLR9
5
Show member pathways
12.86 IFNG IL10 IL17A IL4 STAT1 TNF
6
Show member pathways
12.78 IFNG IL4 STAT1 TLR2 TLR9 TNF
7
Show member pathways
12.57 IFNG IL10 IL17A STAT1 TNF
8
Show member pathways
12.56 IFNG IL10 IL17A IL4 STAT1 TLR2
9
Show member pathways
12.42 IFNG IL10 IL17A IL4 TNF
10
Show member pathways
12.35 IFNG IL17A IL17RA IL4 TLR2 TNF
11
Show member pathways
12.26 IFNG IL10 IL17A IL4 STAT1 TNF
12
Show member pathways
12.24 IFNG IL10 IL4 STAT1 TLR2 TNF
13 12.18 IFNG STAT1 TLR2 TLR9 TNF
14
Show member pathways
12.17 CARD9 CLEC7A IL10 STAT1 TLR9 TNF
15 12.12 CARD9 IFNG IL10 IL17A IL4 STAT1
16
Show member pathways
12.1 IFNG IL4 STAT1 TLR2 TLR9 TNF
17
Show member pathways
12.07 IFNG IL10 IL17A IL4 STAT1
18
Show member pathways
12.03 IFNG IL4 TLR2 TNF
19 12.01 IL10 IL17A IL4 STAT1 TNF
20 11.99 IFNG IL10 IL4 TNF
21 11.88 IFNG IL10 TLR2 TNF
22 11.85 IFNG IL17A TLR2 TNF
23
Show member pathways
11.81 IFNG IL10 IL17A STAT1 TLR2 TLR9
24 11.79 CLEC7A TLR2 TLR9
25 11.77 IFNG IL4 STAT1
26
Show member pathways
11.73 IFNG IL4 TNF
27 11.7 IFNG IL10 IL17RA TLR9 TNF
28 11.64 CD101 IFNG IL10 IL17A IL4 TNF
29 11.62 IFNG IL10 IL17A IL4 TNF
30 11.61 IFNG STAT1 TNF
31 11.53 IL10 IL4 TNF
32 11.51 IFNG TLR2 TNF
33 11.49 IFNG IL10 IL4
34 11.48 CARD9 CLEC7A IFNG IL10 STAT1 TLR2
35 11.41 IFNG IL10 TLR2 TLR9 TNF
36 11.39 IFNG IL10 TLR9 TNF
37 11.33 IFNG IL17A IL4 TNF
38 11.27 IFNG IL10 IL4 TNF
39 11.2 IL10 IL17A IL4 TNF
40 11.2 IFNG IL10 IL4

GO Terms for Opportunistic Mycosis

Biological processes related to Opportunistic Mycosis according to GeneCards Suite gene sharing:

(show all 43)
# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.95 IL10 IL17A IL4 STAT1 TNF
2 defense response to virus GO:0051607 9.93 CARD9 IFNG STAT1 TLR9
3 defense response to Gram-positive bacterium GO:0050830 9.86 CARD9 TLR2 TNF
4 positive regulation of JNK cascade GO:0046330 9.85 CARD9 TLR9 TNF
5 inflammatory response GO:0006954 9.85 CLEC7A IL10 IL17A TLR2 TLR9 TNF
6 I-kappaB kinase/NF-kappaB signaling GO:0007249 9.83 CARD9 TLR9 TNF
7 humoral immune response GO:0006959 9.81 AIRE IFNG TNF
8 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.8 TLR2 TLR9 TNF
9 positive regulation of tumor necrosis factor production GO:0032760 9.79 CARD9 TLR2 TLR9
10 negative regulation of interleukin-6 production GO:0032715 9.71 IL10 TLR9 TNF
11 positive regulation of inflammatory response GO:0050729 9.71 IL17RA TLR2 TLR9 TNF
12 positive regulation of interleukin-8 production GO:0032757 9.7 TLR2 TLR9 TNF
13 negative regulation of growth of symbiont in host GO:0044130 9.69 IL10 TNF
14 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.69 IL10 TNF
15 regulation of cytokine secretion GO:0050707 9.68 TLR2 TLR9
16 regulation of interferon-gamma-mediated signaling pathway GO:0060334 9.68 IFNG STAT1
17 I-kappaB phosphorylation GO:0007252 9.68 TLR2 TLR9
18 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.67 TLR9 TNF
19 endothelial cell apoptotic process GO:0072577 9.66 IL10 TNF
20 interleukin-17-mediated signaling pathway GO:0097400 9.66 IL17A IL17RA
21 negative regulation of interleukin-8 production GO:0032717 9.65 IL10 TLR9
22 positive regulation of interleukin-12 production GO:0032735 9.65 IFNG TLR2 TLR9
23 positive regulation of MHC class II biosynthetic process GO:0045348 9.64 IL10 IL4
24 negative regulation of cytokine secretion involved in immune response GO:0002740 9.63 IL10 TNF
25 positive regulation of osteoclast differentiation GO:0045672 9.63 IFNG IL17A TNF
26 positive regulation of interleukin-18 production GO:0032741 9.61 TLR2 TLR9
27 tumor necrosis factor production GO:0032640 9.61 TLR2 TLR9
28 positive regulation of chemokine production GO:0032722 9.61 TLR2 TLR9 TNF
29 positive regulation of toll-like receptor signaling pathway GO:0034123 9.6 TLR2 TLR9
30 regulation of isotype switching GO:0045191 9.59 IL10 IL4
31 type 2 immune response GO:0042092 9.58 IL10 IL4
32 fibroblast activation GO:0072537 9.58 IL17A IL17RA
33 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.57 IFNG TNF
34 receptor biosynthetic process GO:0032800 9.56 IL10 TNF
35 positive regulation of interleukin-6 production GO:0032755 9.56 CARD9 TLR2 TLR9 TNF
36 positive regulation of vitamin D biosynthetic process GO:0060557 9.51 IFNG TNF
37 positive regulation of nitric-oxide synthase biosynthetic process GO:0051770 9.5 STAT1 TLR2 TLR9
38 response to molecule of bacterial origin GO:0002237 9.33 IL10 TLR2 TLR9
39 immune response GO:0006955 9.23 AIRE IFNG IL10 IL17A IL4 TLR2
40 positive regulation of interleukin-23 production GO:0032747 9.13 IFNG IL17A IL17RA
41 positive regulation of transcription by RNA polymerase II GO:0045944 10.1 AIRE IL10 IL17A IL4 STAT1 TLR2
42 regulation of signaling receptor activity GO:0010469 10.06 IFNG IL10 IL17A IL4 TNF
43 positive regulation of gene expression GO:0010628 10.05 IFNG IL4 TLR2 TLR9 TNF

Molecular functions related to Opportunistic Mycosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.35 IFNG IL10 IL17A IL4 TNF
2 signaling pattern recognition receptor activity GO:0008329 8.8 CLEC7A TLR2 TLR9

Sources for Opportunistic Mycosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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