MCID: OPT077
MIFTS: 17

Optic Disc Pit

Categories: Eye diseases, Fetal diseases, Rare diseases

Aliases & Classifications for Optic Disc Pit

MalaCards integrated aliases for Optic Disc Pit:

Name: Optic Disc Pit 58

Classifications:

Orphanet: 58  
Rare eye diseases
Developmental anomalies during embryogenesis


External Ids:

Orphanet 58 ORPHA519404

Summaries for Optic Disc Pit

MalaCards based summary : Optic Disc Pit is related to retinal detachment and vitreous detachment. Affiliated tissues include eye and retina.

Related Diseases for Optic Disc Pit

Diseases related to Optic Disc Pit via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 60)
# Related Disease Score Top Affiliating Genes
1 retinal detachment 10.8
2 vitreous detachment 10.7
3 retinoschisis 1, x-linked, juvenile 10.6
4 macular holes 10.5
5 coloboma of macula 10.4
6 intraocular pressure quantitative trait locus 10.4
7 open-angle glaucoma 10.3
8 glaucoma, primary open angle 10.3
9 scotoma 10.3
10 retinitis pigmentosa 10.2
11 yemenite deaf-blind hypopigmentation syndrome 10.2
12 keratoconus 10.2
13 neuroretinitis 10.2
14 orbital cyst 10.2
15 retinitis 10.2
16 night blindness 10.2
17 ocular hypertension 10.2
18 refractive error 10.2
19 blood group--newfoundland 10.0
20 cleft palate, isolated 10.0
21 distichiasis 10.0
22 optic nerve hypoplasia, bilateral 10.0
23 septooptic dysplasia 10.0
24 meningioma, radiation-induced 10.0
25 glaucoma, normal tension 10.0
26 meningioma, familial 10.0
27 microvascular complications of diabetes 5 10.0
28 joint laxity, short stature, and myopia 10.0
29 cone dystrophy 10.0
30 scoliosis 10.0
31 hereditary lymphedema i 10.0
32 hypogonadotropic hypogonadism 10.0
33 suppression amblyopia 10.0
34 amblyopia 10.0
35 juvenile glaucoma 10.0
36 meningocele 10.0
37 arteriovenous malformation 10.0
38 spinal meningioma 10.0
39 myopia 10.0
40 telangiectasis 10.0
41 primary angle-closure glaucoma 10.0
42 papilledema 10.0
43 retinal vascular disease 10.0
44 hemangioma 10.0
45 macular retinal edema 10.0
46 secretory meningioma 10.0
47 lymphoplasmacyte-rich meningioma 10.0
48 cavernous hemangioma 10.0
49 cataract 10.0
50 cleft lip 10.0

Graphical network of the top 20 diseases related to Optic Disc Pit:



Diseases related to Optic Disc Pit

Symptoms & Phenotypes for Optic Disc Pit

Drugs & Therapeutics for Optic Disc Pit

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Vitrectomy Without Laser or Gas Tamponade for Optic Disc Pit Maculopathy Completed NCT01340703
2 Macular Retinoschisis and Detachment Associated With Glaucomatous Optic Neuropathy But Without Optic Disc Pit Nor High Myopia Completed NCT01862627
3 Pars Plana Vitrectomy With Internal Limiting Membrane Peeling in Optic Disc Pit Maculopathy Completed NCT03185936

Search NIH Clinical Center for Optic Disc Pit

Genetic Tests for Optic Disc Pit

Anatomical Context for Optic Disc Pit

MalaCards organs/tissues related to Optic Disc Pit:

40
Eye, Retina

Publications for Optic Disc Pit

Articles related to Optic Disc Pit:

(show top 50) (show all 228)
# Title Authors PMID Year
1
Newly Onset Optic Disc Pit Maculopathy (ODP-M) in a Patient With Primary Angle-closure Glaucoma (PACG) After Surgical Iridectomy: A Case Report. 61
32282435 2020
2
A prospective long-term follow-up study of optic disc pit maculopathy treated with pars plana vitrectomy, drainage of subretinal fluid and peeling of internal limiting membrane. 61
32421253 2020
3
Spontaneous resolution of serous macular detachment and outer retinal defect in optic disc pit maculopathy. 61
31155752 2020
4
Commentary: Current trends in the management of optic disc pit maculopathy. 61
32174601 2020
5
Sulphur hexafluoride (SF6) intravitreal injection combined with argon laser photocoagulation for treatment of optic disc pit maculopathy. 61
32317789 2020
6
Management of double optic disc pit complicated by maculopathy. 61
32174600 2020
7
Oral acetazolamide as a medical adjuvant to retinal surgery in optic disc pit maculopathy in a pediatric patient. 61
31993534 2020
8
Resolution of optic disc pit-associated macular retinoschisis after topical carbonic anhydrase inhibitor treatment: Report of a case. 61
32019335 2020
9
Comparison of various surgical techniques for optic disc pit maculopathy: vitrectomy with internal limiting membrane (ILM) peeling alone versus inverted ILM flap 'plug' versus autologous scleral 'plug'. 61
32029434 2020
10
Successful use of a silicone lacrimal plug to treat a case of refractory macular detachment associated with a large optic disc pit. 61
31976631 2020
11
Intraoperative optical coherence tomography findings during surgery for optic disc pit-associated maculopathy. 61
32399425 2020
12
Inverted internal limiting membrane flap for the management of optic disc pit maculopathy. 61
31691728 2020
13
Optic Disc Pit Maculopathy - Case Series, Clinical Approach, and Management. 61
32549722 2020
14
Microscope-Integrated Optical Coherence Tomography-Guided Autologous Full-Thickness Neurosensory Retinal Autograft for Large Macular Hole-Related Total Retinal Detachment. 61
31929416 2020
15
A new mutation in the PAX2 gene in a Papillorenal Syndrome patient. 61
31692565 2019
16
A hybrid coloboma and optic disc pit associated with macular retinoschisis. 61
31684897 2019
17
Optic Disc Pit Maculopathy: New Perspectives on the Natural History. 61
31095956 2019
18
[Macular changes in optic disc pits-Optic disc pit maculopathy (ODP-M) : Pathophysiology and possibilities of surgical treatment]. 61
31338589 2019
19
[Erratum to: Macular changes in optic disc pits-Optic disc pit maculopathy (ODP-M). Pathophysiology and possibilities of surgical treatment]. 61
31641847 2019
20
Anterior Lens Capsule Transplantation for Acquired Optic Disc Pit Maculopathy. 61
31671198 2019
21
[Congenital abnormalities of the optic disc]. 61
30935696 2019
22
Macular Structure Recovery after Surgery for Optic Disc Pit Maculopathy. 61
31911783 2019
23
[Daytime Fluctuations of Subretinal Fluid in Optic Disc Pit Maculopathy]. 61
31416095 2019
24
Optic disc pit maculopathy: a review of diagnosis and treatment. 61
31441129 2019
25
Optic disc pit maculopathy and its spectrum of management. 61
31332128 2019
26
[Minimal Variant of an Optic Disc Pit with Cecocentral Scotoma Due to Limited Progressive Retinal Ganglion Cell Atrophy - a Case Report]. 61
31266071 2019
27
Optic Nerve Sheath Meningocele With Optic Disc Pit: A Rare Finding. 61
30664128 2019
28
Optic Disc Pit Maculopathy: A Review. 61
31179667 2019
29
[Optic disc pit combined with interpapillo-macular ganglion cells hypoplasia]. 61
30685116 2019
30
A Case of Optic Disc Pit Maculopathy Observed without Intervention for 6 Years. 61
31014772 2019
31
New Observations regarding the Assessment of Cilioretinal Arteries Coexistence with Optic Disc Pit. 61
31244378 2019
32
Efficacy of Internal Limiting Membrane Flap Techniques with Vitrectomy for Macular Detachment Associated with an Optic Disc Pit. 61
30808833 2019
33
Optic disc pit maculopathy: tamponade of maculoschisis. 61
31564824 2019
34
BILATERAL OPTIC DISC PIT WITH MACULOPATHY - THE CASE REPORT. 61
31537077 2019
35
Optic Disc Pit With Peripapillary Retinoschisis Misdiagnosed as Glaucoma. 61
30629116 2019
36
Prevalence of the optic disc anomalies in the adult South Indian population. 61
29567792 2019
37
Clinicopathologic Correlation of the Optic Pit Glial Plug in Optic Disc Pit Maculopathy. 61
30566716 2018
38
Fibrin Glue and Internal Limiting Membrane Abrasion for Optic Disc Pit Maculopathy. 61
30566713 2018
39
Comparison of Inverted ILM-Stuffing Technique and ILM Peeling Alone for Optic Disc Pit-Associated Maculopathy: Long-Term Results. 61
30566707 2018
40
Optic Disc Pit Maculopathy: A Two-Year Nationwide Prospective Population-based Study. 61
29887331 2018
41
Multicolour imaging in a patient with optic disc pit maculopathy. 61
29701308 2018
42
Central serous chorioretinopathy in a patient of juxtapapillary excavation misdiagnosed as optic disc pit maculopathy. 61
30389738 2018
43
Surgical outcome in optic disc pit maculopathy. 61
30505129 2018
44
27-Gauge Via Pars Plana Vitrectomy With Autologous ILM Transplantation for Optic Pit Disc Maculopathy. 61
30222807 2018
45
Visualization of Capillary Dropout Emanating From an Optic Disc Pit Using Optical Coherence Tomography Angiography. 61
30098183 2018
46
Optic disc pit maculopathy. 61
29666483 2018
47
Micropulse laser for persistent optic disc pit maculopathy. A case report. 61
29780953 2018
48
Optic disc pit maculopathy. 61
28994138 2018
49
Vitrectomy for optic disc pit maculopathy: a long-term follow-up study. 61
29411099 2018
50
Active Cone Regeneration Following Autologous Internal Limiting Membrane 'Chunk' Transplantation in Optic Disc Pit-Associated Maculopathy. 61
29443368 2018

Variations for Optic Disc Pit

Expression for Optic Disc Pit

Search GEO for disease gene expression data for Optic Disc Pit.

Pathways for Optic Disc Pit

GO Terms for Optic Disc Pit

Sources for Optic Disc Pit

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....