Drugs for Optic Nerve Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):
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(show all 209)
# |
|
Name |
Status |
Phase |
Clinical Trials |
Cas Number |
PubChem Id |
1 |
|
Prednisolone phosphate |
Approved, Vet_approved |
Phase 4 |
|
302-25-0 |
|
Synonyms:
Prednisolone 21-(dihydrogen phosphate)
Prednisolone 21-monophosphate
|
Prednisolone 21-phosphate
|
|
2 |
|
Prednisolone acetate |
Approved, Vet_approved |
Phase 4 |
|
52-21-1 |
|
Synonyms:
ECONOPRED
FLO-PRED
METICORTELONE
NSC-10966
OMNIPRED
PRED FORTE
|
PRED FTE
PRED MILD
PREDNISOLONE 21-ACETATE
PREDNISOLONE ACETATE
STERANE
ULTRACORTENOL
|
|
3 |
|
Prednisolone |
Approved, Vet_approved |
Phase 4 |
|
50-24-8 |
4894 5755 |
Synonyms:
(11b)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
(11Î’)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione
1,4-Pregnadiene-11b,17a,21-triol-3,20-dione
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-11β,17α,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11b,17a,21-triol
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1,4-Pregnadiene-3,20-dione-11β,17α,21-triol
3,20-Dioxo-11b,17a,21-trihydroxy-1,4-pregnadiene
3,20-Dioxo-11beta,17alpha,21-trihydroxy-1,4-pregnadiene
3,20-Dioxo-11β,17α,21-trihydroxy-1,4-pregnadiene
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
Codelcortone
Co-Hydeltra
Cordrol
CORTALONE
Cotogesic
Cotolone
Decaprednil
Decortin H
DEKOTIL
Delcortol
Delta F
Delta(1)-Dehydrocortisol
Delta(1)-Dehydrohydrocortisone
Delta(1)-Hydrocortisone
DELTA.1-CORTISOL
DELTA.1-Cortisol|Orapred®|Pediapred®
Delta-Cortef
Deltacortenol
DELTACORTRIL
Deltacortril Enteric
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
Deltahydrocortisone
DELTALONE
Deltasolone
Delta-Stab
Deltisilone
Depo-Medrol
Derpo Pd
DESOWEN
Dexa-Cortidelt Hostacortin H
Di adreson F
Di-Adreson F
Di-adreson-F
DiAdresonF
Dicortol
DILACORT
Donisolone
Dydeltrone
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
FERNISOLONE-P
Flamasone
Hostacortin H
HYDELTRA
Hydeltrasol
HYDELTRA-TBA
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
IMS904
Inflamase Forte
Inflamase Mild
I-Pred
Key-Pred
Klismacort
Lentosone
Lite Pred
Medrol
|
Medrol Acetate
Metacortandralone
Methylprednisolone acetate
METICORTELONE
METI-DERM
Metreton
M-Predrol
NEO-DELTA-CORTEF
Nisolone
Nor-Pred T.B.A.
NSC-9120
NSC-9900
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
ORAPRED
Panafcortelone
Paracortol
Paracotol
PEDIAPRED
PEVANTI
POLY-PRED
PRDL
Precortalon
Precortancyl
Precortilon
PRECORTISYL
PRECORTISYL FTE
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
PRED-G
Predisolone sodium phosphate
PREDL
Predne-Dome
Prednelan
Prednicen
Predni-Dome
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone
Prednisolone acetate
Prednisolone sodium phosphate
Prednisolone tebutate
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
PRELONE
Prenolone
Rolisone
SCHERIPROCT
Scherisolon
SERVISONE
Solone
Steran
STERANE
Sterolone
Supercortisol
TRIDESILON
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
VERDESO
Δ(1)-dehydrocortisol
Δ(1)-dehydrohydrocortisone
Δ(1)-hydrocortisone
Δ-cortef
|
|
4 |
|
Prednisone |
Approved, Vet_approved |
Phase 4 |
|
53-03-2 |
5865 |
Synonyms:
1,2-Dehydrocortisone
1,4-Pregnadiene-17a,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17α,21-diol-3,11,20-trione
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
Acis brand OF prednisone
Acsis, prednison
Adasone
Ancortone
Apo-prednisone
Apotex brand OF prednisone
Aventis brand OF prednisone
Betapar
Bicortone
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
Cutason
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta-cortelan
Deltacortene
delta-Cortisone
Deltacortisone
Deltacortone
Delta-cortone
DELTA-DOME
Deltasone
Deltison
Deltisona
Deltisone
Deltra
Diadreson
Di-Adreson
Diba brand OF prednisone
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fawns and mcallan brand OF prednisone
FERNISONE
Ferring brand OF prednisone
Fiasone
GALENpharma brand OF prednisone
Halsey drug brand OF prednisone
Hexal brand OF prednisone
Hoechst brand OF prednisone
Hostacortin
ICN brand OF prednisone
Incocortyl
In-Sone
Juvason
Kortancyl
Lichtenstein brand OF prednisone
|
Liquid pred
Lisacort
LODOTRA
Lodotra®|Sterapred®
Me-Korti
Merck brand OF prednisone
Merz brand OF prednisone
Metacortandracin
Meticorten
Mibe brand OF prednisone
Nisona
Nizon
Novoprednisone
NSC-10023
Nurison
Orasone
Origen Prednisone
Panafcort
Panasol
PARACORT
Parmenison
Pehacort
Pharmacia brand OF prednisone
PRD
Precort
Predeltin
PREDN
Predni tablinen
PREDNICEN-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Predniment
Prednison
Prednison acsis
Prednison galen
Prednison hexal
Prednisona
Prednisona [INN-Spanish]
Prednisone
PREDNISONE INTENSOL
PREDNISONE TABLETS
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Pronison
Pronisone
RAYOS
Rectodelt
Retrocortine
Schering-plough brand OF prednisone
Seatrace brand OF prednisone
SERVISONE
Solvay brand OF prednisone
Sone
Sterapred
Supercortil
Trommsdorff brand OF prednisone
Ultracorten
Ultracortene
Winpred
Wojtab
Zenadrid
|
|
5 |
|
Methylprednisolone hemisuccinate |
Approved |
Phase 4 |
|
2921-57-5 |
1875 |
Synonyms:
Methylprednisolone hemisuccinate
Methylprednisolone hemisuccinic acid
|
Methylprednisolone hydrogen succinate
Methylprednisolone succinate
|
|
6 |
|
Methylprednisolone |
Approved, Vet_approved |
Phase 4 |
|
83-43-2 |
4159 6741 |
Synonyms:
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6Α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
1-Dehydro-6alpha-methylhydrocortisone
1-Dehydro-6a-methylhydrocortisone
1-Dehydro-6α-methylhydrocortisone
6 Methylprednisolone
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6a-Methyl-11b,17a,21-triol-1,4-pregnadiene-3,20-dione
6a-Methylprednisolone
6-Methylprednisolone
6Α-methyl-11β,17α,21-triol-1,4-pregnadiene-3,20-dione
6Α-methylprednisolone
Artisone-Wyeth
Besonia
Delta(1)-6alpha-Methylhydrocortisone
delta(1)-6a-Methylhydrocortisone
Dopomedrol
Esametone
Firmacort
J3.872E
Lemod
Medesone
Medixon
Medlone 21
Medrate
Medric acid
Medrol
Medrol Adt Pak
Medrol Dosepak
Medrol®|U-67590A
Medrone
Mesopren
|
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
Nirypan
Noretona
NSC-19987
Predni N Tablinen
Promacortine
Reactenol
Sieropresol
Solomet
SOLU-MEDROL
Summicort
Suprametil
U-67590A
Urbason
Urbasone
Wyacort
Δ(1)-6a-methylhydrocortisone
Δ(1)-6α-methylhydrocortisone
|
|
7 |
|
Carbidopa |
Approved |
Phase 4 |
|
28860-95-9 |
34359 38101 |
Synonyms:
(-)-L-a-Hydrazino-3,4-dihydroxy-a-methylhydrocinnamate
(-)-L-a-Hydrazino-3,4-dihydroxy-a-methylhydrocinnamic acid
(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamate
(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid
(-)-L-ALPHA-HYDRAZINO-3,4-DIHYDROXY-ALPHA-METHYLHYDROCINNAMIC ACID MONOHYDRATE
(-)-L-Α-hydrazino-3,4-dihydroxy-α-methylhydrocinnamate
(-)-L-Α-hydrazino-3,4-dihydroxy-α-methylhydrocinnamic acid
(2S)-3-(3,4-DIHYDROXYPHENYL)-2-HYDRAZINYL-2-METHYLPROPANOIC ACID HYDRATE
(2S)-3-(3,4-DIHYDROXYPHENYL)-2-HYDRAZINYL-2-METHYLPROPANOIC ACID MONOHYDRATE
(AlphaS)-a-hydrazino-3,4-dihydroxy-a-methylbenzenepropanoate
(AlphaS)-a-hydrazino-3,4-dihydroxy-a-methylbenzenepropanoic acid
(AlphaS)-alpha-hydrazino-3,4-dihydroxy-alpha-methylbenzenepropanoate
(AlphaS)-alpha-hydrazino-3,4-dihydroxy-alpha-methylbenzenepropanoic acid
(ALPHAS)-ALPHA-HYDRAZINO-3,4-DIHYDROXY-ALPHA-METHYLBENZENEPROPANOIC ACID MONOHYDRATE
(AlphaS)-α-hydrazino-3,4-dihydroxy-α-methylbenzenepropanoate
(AlphaS)-α-hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic acid
(S)-(−)-carbidopa
(S)-(-)-Carbidopa
(S)-(-)-CARBIDOPA HYDRATE
(S)-(−)-CARBIDOPA HYDRATE
(S)-Carbidopa
(S)-CARBIDOPA HYDRATE
|
(αS)-α-hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic acid
Carbidopa
Carbidopa (anhydrous)
CARBIDOPA ANHYDROUS
CARBIDOPA HYDRATE
CARBIDOPA MONOHYDRATE
Carbidopa, (R)-isomer
Carbidopa, (S)-isomer
Carbidopum
CARBIDOPUM MONOHYDRICUM
CDP536
Duodopa®|Lodosyn®|MK 486
L-3-(3,4-Dihydroxyphenyl)-2-methyl-2-hydrazinopropionate
L-3-(3,4-Dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid
L-ALPHA-(3,4-DIHYDROXYBENZYL)-ALPHA-HYDRAZINOPROPIONIC ACID MONOHYDRATE
L-alpha-Methyldopahydrazine
L-a-Methyldopahydrazine
Lodosin
Lodosyn
L-Α-methyldopahydrazine
Methyldopahydrazine
MK-486
|
|
8 |
|
Levodopa |
Approved |
Phase 4 |
|
59-92-7, 63-84-3 |
6047 |
Synonyms:
(-)-3-(3,4-Dihydroxyphenyl)-L-alanine
(−)-3-(3,4-DIHYDROXYPHENYL)-L-ALANINE
(-)-Dopa
(−)-DOPA
(+-)-3-(3,4-Dihydroxyphenyl)alanine
(+-)-Dopa
(+/-) 3-(3,4-dihydroxyphenyl)alanine
(2S)-2-Amino-3-(3,4-dihydroxyphenyl)propanoate
(2S)-2-Amino-3-(3,4-dihydroxyphenyl)propanoic acid
(R,S)-Dopa
2-amino-3-(3,4-Dihydroxyphenyl)propanoate
2-amino-3-(3,4-Dihydroxyphenyl)propanoic acid
3 Hydroxy DL tyrosine
3 Hydroxy L tyrosine
3-(3,4-Dihydroxyphenyl)-DL-alanine
3-(3,4-Dihydroxyphenyl)-L-alanine
3,4 Dihydroxyphenylalanine
3,4-Dihydroxy-DL-phenylalanine
3,4-Dihydroxy-L-phenylalanine
3,4-dihydroxy-L-phenylalanine|Inbrija® (levodopa inhalation powder)|L-DOPA|Sinemet®
3,4-Dihydroxyphenylalanine
3',4'-Dihydroxyphenylalanine
3,4-Dihydroxyphenyl-L-alanine
3-Hydroxy-DL-tyrosine
3-Hydroxy-L-tyrosine
3-Hydroxytyrosine
a-amino-3,4-Dihydroxy-benzenepropanoate
a-amino-3,4-Dihydroxy-benzenepropanoic acid
alpha-amino-3,4-Dihydroxy-benzenepropanoate
alpha-amino-3,4-Dihydroxy-benzenepropanoic acid
alpha-amino-Hydrocaffeic acid
b-(3,4-Dihydroxyphenyl)-a-alanine
b-(3,4-Dihydroxyphenyl)-a-L-alanine
b-(3,4-Dihydroxyphenyl)alanine
b-(3,4-Dihydroxyphenyl)-DL-a-alanine
b-(3,4-Dihydroxyphenyl)-L-alanine
Bendopa
beta Hydroxytyrosine
beta-(3,4-Dihydroxyphenyl)alanine
beta-(3,4-Dihydroxyphenyl)-alpha-alanine
beta-(3,4-Dihydroxyphenyl)-alpha-L-alanine
beta-(3,4-Dihydroxyphenyl)-DL-alpha-alanine
beta-(3,4-Dihydroxyphenyl)-L-alanine
beta-Hydroxytyrosine
BROCADOPA
Cidandopa
Deadopa
Dihydroxy-L-phenylalanine
Dihydroxyphenylalanine
Dihydroxyphenylalanine hydrochloride, (2:1)
DL-3,4-Dihydroxyphenylalanine
DL-3',4'-Dihydroxyphenylalanine
DL-3,4-Dopa
DL-3-Hydroxytyrosine
DL-4,5-Dihydroxyphenylalanine
DL-b-(3,4-Dihydroxyphenyl)-a-alanine
DL-b-(3,4-Dihydroxyphenyl)alanine
DL-beta-(3,4-Dihydroxyphenyl)alanine
DL-beta-(3,4-Dihydroxyphenyl)-alpha-alanine
DL-Dihydroxyphenylalanine
DL-Dioxyphenylalanine
|
DL-Î’-(3,4-dihydroxyphenyl)alanine
DL-Β-(3,4-dihydroxyphenyl)-α-alanine
Dopa
Dopaflex
Dopaidan
Dopal
Dopal-Fher
Dopalina
Dopar
Doparkine
Doparl
Dopasol
Dopaston
Dopastone
Dopastral
Dopicar
Doprin
Eldopal
Eldopar
Eldopatec
Eurodopa
Helfo-dopa
INBRIJA
Insulamina
L 3,4 Dihydroxyphenylalanine
L Dopa
L-(-)-Dopa
L-3-(3,4-Dihydroxyphenyl)-alanine
L-3,4-Dihydroxyphenylalanine
L-4-5-Dihydroxyphenylalanine
Laradopa
Larodopa
L-b-(3,4-Dihydroxyphenyl)-a-alanine
L-b-(3,4-Dihydroxyphenyl)alanine
L-beta-(3,4-Dihydroxyphenyl)alanine
L-beta-(3,4-Dihydroxyphenyl)-alpha-alanine
L-Dihydroxyphenylalanine
L-DOPA
LDP540
Ledopa
Levedopa
Levodopa
Levodopum
Levopa
L-Î’-(3,4-dihydroxyphenyl)alanine
Maipedopa
Medphano brand OF levodopa
NSC-118381
Parda
Pardopa
Prodopa
Roberts brand OF levodopa
Roche brand OF levodopa
SINEMET
Syndopa
V-1512
Veldopa
Weldopa
Î’-(3,4-dihydroxyphenyl)alanine
Β-(3,4-dihydroxyphenyl)-DL-α-alanine
Î’-(3,4-dihydroxyphenyl)-L-alanine
|
|
9 |
|
Dalfampridine |
Approved |
Phase 4 |
|
504-24-5 |
1727 |
Synonyms:
4-AMINOPYRIDINE
4-aminopyridine|4-AP|Ampyra®|EL-970
4-AP
4-PYRIDINAMINE
4-PYRIDYLAMINE
AMPYRA
AMPYRA EXTENDED RELEASE
AVITROL
DALFAMPRIDINE
EL-970
FAMPRIDINA
|
FAMPRIDINE
FAMPRIDINE-SR
FAMPRIDINUM
FAMPYRA
GAMMA-AMINOPYRIDINE
N07XX07
NEURELAN
NSC-15041
P-AMINOPYRIDINE
γ-Aminopyridine
|
|
10 |
|
Sildenafil |
Approved, Investigational |
Phase 4 |
|
139755-83-2, 171599-83-0 |
5212 135398744 |
Synonyms:
1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-D)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine
1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-D)pyrimidin-5-yl)-4-ethoxyphenyl)sulphonyl)-4-methylpiperazine
1-((3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-D)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
1-{[3-(4,7-DIHYDRO-1-METHYL-7-OXO-3-PROPYL-1H-PYRAZOLO[4,3-D]PYRIMIDIN-5-YL)-4-ETHOXYPHENYL]SULFONYL}-4-METHYLPIPERAZINE
5-[2-ETHOXY-5-(4-METHYLPIPERAZIN-1-YLSULFONYL)PHENYL]-1-METHYL-3-PROPYL-1H-PYRAZOLO[4,3-D]PYRIMIDIN-7(6H)-ONE
5-[2-ETHOXY-5-(4-METHYL-PIPERAZINE-1-SULFONYL)-PHENYL]-1-METHYL-3-PROPYL-1,6-DIHYDRO-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE
Acetildenafil
Aphrodil
Caverta
Citrate, sildenafil
Desmethyl sildenafil
Desmethylsildenafil
HIP0908
HIP-0908
Homosildenafil
Hydroxyhomosildenafil
Lactate, sildenafil
NCX 911
|
NCX-911
NIPATRA
Nitrate, sildenafil
Revatio
Sildenafil
Sildenafil citrate
Sildenafil lactate
Sildenafil nitrate
Sildenafil Viagra
Sildenafil, desmethyl
Sildenafilo
UK-92480
UK-9248010
UK-92480-10
Viagra
Viagra®
VIZARSIN
|
|
11 |
|
Tadalafil |
Approved, Investigational |
Phase 4 |
|
171596-29-5 |
110635 |
Synonyms:
(6R,12AR)-2,3,6,7,12,12a-hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
(6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
351, IC
6-BENZO[1,3]dioxol-5-yl-2-methyl-2,3,6,7,12,12a-hexahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
Adcirca
Adcirca®|Cialis®|IC-351|IC351
Cialis
|
IC351
IC-351
ICOS 351
Tadalafil
Tadalafilo
Tadanafil
Zalutia
|
|
12 |
|
Prednisolone hemisuccinate |
Experimental |
Phase 4 |
|
2920-86-7 |
4897 |
Synonyms:
(+)-prednisolone hemisuccinate
4-(2-{14,17-dihydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.0,.0,]heptadeca-3,6-dien-14-yl}-2-oxoethoxy)-4-oxobutanoate
Prednisolonbisuccinat
Prednisolone 21-hemisuccinate
Prednisolone 21-succinate
|
Prednisolone bisuccinate
PREDNISOLONE HEMISUCCINATE
Prednisolone hemisuccinic acid
Prednisolone hydrogen succinate
PREDNISOLONE SUCCINATE
|
|
13 |
|
Neurotransmitter Agents |
|
Phase 4 |
|
|
|
14 |
|
Adrenergic Agents |
|
Phase 4 |
|
|
|
15 |
|
Antihypertensive Agents |
|
Phase 4 |
|
|
|
16 |
|
Pharmaceutical Solutions |
|
Phase 4 |
|
|
|
17 |
|
Methylprednisolone Acetate |
|
Phase 4 |
|
|
584547 |
Synonyms:
Acetyl methylprednisolone
Acetyl-methylprednisolone
DEPMEDALONE
Depo medrol
Depo medrone
Depo-medrol
Depo-medrone
|
MEDROL ACETATE
Methylprednisolone 21 acetate
METHYLPREDNISOLONE ACETATE
Methylprednisolone acetate, (11beta,16alpha)-isomer
Methylprednisolone acetate, (11beta,16beta)-isomer
Methylprednisolone acetic acid
Methylprednisolone-21-acetate
|
|
18 |
|
Antineoplastic Agents, Hormonal |
|
Phase 4 |
|
|
|
19 |
|
Hormones |
|
Phase 4 |
|
|
|
20 |
|
Hormone Antagonists |
|
Phase 4 |
|
|
|
21 |
|
glucocorticoids |
|
Phase 4 |
|
|
|
22 |
|
Anti-Inflammatory Agents |
|
Phase 4 |
|
|
|
23 |
|
Carbidopa, levodopa drug combination |
|
Phase 4 |
|
|
|
24 |
|
Adjuvants, Immunologic |
|
Phase 4 |
|
|
|
25 |
|
Dopamine agonists |
|
Phase 4 |
|
|
|
26 |
|
Antiparkinson Agents |
|
Phase 4 |
|
|
|
27 |
|
Aromatic Amino Acid Decarboxylase Inhibitors |
|
Phase 4 |
|
|
|
28 |
|
Immunologic Factors |
|
Phase 4 |
|
|
|
29 |
|
Potassium Channel Blockers |
|
Phase 4 |
|
|
|
30 |
|
Ophthalmic Solutions |
|
Phase 4 |
|
|
|
31 |
|
Brimonidine Tartrate |
|
Phase 4 |
|
70359-46-5 |
|
Synonyms:
AGN-190342LF
AGN-190342-LF
ALPHAGAN
ALPHAGAN P
BRIMONIDINE D-TARTRATE
BRIMONIDINE TARTRATE
|
BRYMONT
LUMIFY
MIRVASO
QOLIANA
UK-1430418
|
|
32 |
|
Adrenergic alpha-Agonists |
|
Phase 4 |
|
|
|
33 |
|
Adrenergic Agonists |
|
Phase 4 |
|
|
|
34 |
|
Ginkgo |
|
Phase 4 |
|
|
|
Synonyms:
B1260
EGB 761
EGB-761
GINKGO
GINKGO BILOBA EXTRACT
|
GINKGO BILOBA LEAF
GINKGO BILOBA LEAF DRY EXTRACT
GINKGO BILOBA LEAF EXTRACT
GINKGO BILOBA LEAF TINCTURE
|
|
35 |
|
Phosphodiesterase 5 Inhibitors |
|
Phase 4 |
|
|
|
36 |
|
Vardenafil Dihydrochloride |
|
Phase 4 |
|
|
|
37 |
|
Curcumin |
Approved, Investigational |
Phase 3 |
|
458-37-7, 84765-67-3 |
969516 |
Synonyms:
1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
1,9-Bis(4-hydroxy-3-methoxyphenyl)-2,7-nonadiene-4,6-dione
14a-Methyl-9,19-cyclo-5a,9b-cholestane-3b,6a-diol
C.I. 75300
C.I. natural yellow 3
CI natural yellow 3
CI-75300
Cucurmin
Curcuma
CURCUMIN
Curcumin I
Diferaloylmethane
Diferuloylmethane
e 100
E100
E-100
Gelbwurz
Golden seal
Haidr
Halad
Haldar
Halud
|
Hydrastis
INS NO. 100(I)
INS-100(I)
Kacha haldi
Merita earth
Natural yellow 3
NSC-32982
NSC-687842
Orange root
Safran d'inde
Souchet
Terra merita
Tumeric yellow
Turmeric
Turmeric (>98% curcurmin)
Turmeric oleoresin (79%-85% curcumin)
Turmeric yellow
Yellow ginger
Yellow puccoon
Yellow root
Yellow, turmeric
Yo-kin
|
|
38 |
|
Bosentan |
Approved, Investigational |
Phase 3 |
|
147536-97-8 |
104865 |
Synonyms:
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulphornamide
4-t-Butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide
BOSENTAN
BOSENTÁN
Bosentan anhydrous
Bosentan hydrate
Bosentan monohydrate
|
Bosentanum
p-Tert-butyl-N-(6-(2-hydroxyethoxy)-5-(O-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide
p-Tert-butyl-N-(6-(2-hydroxyethoxy)-5-(O-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulphonamide
RO 47-0203
RO 47-0203|Tracleer®
RO-470203029
RO-47-0203-029
Tracleer
|
|
39 |
|
Bezafibrate |
Approved, Investigational |
Phase 2, Phase 3 |
|
41859-67-0 |
39042 |
Synonyms:
2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionate
2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid
Azufibrat
Azupharma brand OF bezafibrate
Bayer brand OF bezafibrate
Befibrat
Befizal
Béfizal
Berlin chemie brand OF bezafibrate
Berlin-chemie brand OF bezafibrate
Betapharm brand OF bezafibrate
Beza lande
Beza puren
Bezabeta
Bezacur
Bezafibrat
Bezafibrat PB
BEZAFIBRATE
Bezafibrate azupharma brand
Bezafibrate bayer brand
Bezafibrate berlin-chemie brand
Bezafibrate betapharm brand
Bezafibrate cryopharma brand
Bezafibrate elfar brand
Bezafibrate hennig brand
Bezafibrate hexal brand
Bezafibrate isis brand
Bezafibrate lakeside brand
Bezafibrate merckle brand
Bezafibrate roche brand
Bezafibrate synthelabo brand
Bezafibrate tad brand
Bezafibrate teva brand
Bezafibrato
Bezafibratum
Bezafibric acid
Bezafisal
BEZAGEN XL
|
Beza-lande
BezaLande
Bezalip
Bezalip®
BEZALIP-MONO
Bezamerck
Beza-puren
BezaPuren
Bezatol SR
BEZATOL SR (TN)
BM 15.075
BM-15.075
BM-15075
Boehringer mannheim brand OF bezafibrate
Cedur
Cryopharma brand OF bezafibrate
Difaterol
Durabezur
Elfar brand OF bezafibrate
Eulitop
FIBRAZATE XL
Hennig brand OF bezafibrate
Hexal brand OF bezafibrate
Isis brand OF bezafibrate
Lakeside brand OF bezafibrate
LIPAROL XL
Lipox
Merckle brand OF bezafibrate
PB, Bezafibrat
Reducterol
Regadrin b
Roche brand OF bezafibrate
Sklerofibrat
Solibay
Synthelabo brand OF bezafibrate
TAD brand OF bezafibrate
Teva brand OF bezafibrate
ZIMBACOL XL
|
|
40 |
|
Nalbuphine |
Approved |
Phase 3 |
|
20594-83-6 |
5311304 |
Synonyms:
Hydrochloride, nalbuphine
Intapan
Nalbufina
NALBUPHIN
NALBUPHINE
Nalbuphine hydrochloride
Nalbuphine serb
Nalbuphine serb brand
|
Nalbuphinum
N-Cyclobutylmethyl-4,5a-epoxy-3,6a,14-morphinantriol
N-Cyclobutylmethyl-4,5alpha-epoxy-3,6alpha,14-morphinantriol
N-Cyclobutylmethyl-4,5α-epoxy-3,6α,14-morphinantriol
Nubain
Nubain®
SERB brand OF nalbuphine
Serb, nalbuphine
|
|
41 |
|
Midazolam |
Approved, Illicit |
Phase 3 |
|
59467-70-8 |
4192 |
Synonyms:
Buccolam
Buccolam®|Dormicum®|Nayzilam®|USL261 (nasal spray formulation)|Versed®
Dea no. 2884
Dormicum
Hydrochloride, midazolam
Maleate, midazolam
Mezolam
Midazolam
Midazolam base
MIDAZOLAM CIV
|
Midazolam Hcl
Midazolam hydrochloride
Midazolam maleate
Midazolamum
Midazolamum [INN-Latin]
Nayzilam
USL261
USL-261
Versed
|
|
42 |
|
Magnesium sulfate |
Approved, Investigational, Vet_approved |
Phase 3 |
|
7487-88-9 |
|
Synonyms:
Magnesium sulfate (1:1)
Magnesium sulfate anhydrous
Magnesium sulphate
|
magnesium(II) sulfate
Magnesiumsulfat
MgSO4
|
|
43 |
|
Dexmedetomidine |
Approved, Experimental, Vet_approved |
Phase 3 |
|
86347-14-0, 113775-47-6 |
68602 5311068 |
Synonyms:
(+)-4-((S)-a,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-Α,2,3-trimethylbenzyl)imidazole
(+-)-4-(a,2,3-Trimethylbenzyl)imidazole
(+-)-4-(alpha,2,3-Trimethylbenzyl)imidazole
(+-)-4-(Α,2,3-trimethylbenzyl)imidazole
(+)-MEDETOMIDINE
(±)-4-(α,2,3-trimethylbenzyl)imidazole
(S)-MEDETOMIDINE
Dexdor
Dexdor®|Igalmi® (dexmedetomidine sublingual film)|MPV 1440|Precedex®
DEXMEDETOMIDIN
Dexmedetomidina
DEXMEDETOMIDINE
DEXMÉDÉTOMIDINE
Dexmedetomidine hydrochloride
Dexmedetomidinum
|
Domitor
Hospira brand OF dexmedetomidine hydrochloride
Hydrochloride, dexmedetomidine
Hydrochloride, medetomidine
Levomedetomidine
Medetomidina
Medetomidina [Spanish]
Medetomidine
Medetomidine hydrochloride
Medetomidinum
Medetomidinum [Latin]
MPV 1440
MPV 785
MPV-1440
MPV-785
Precedex
|
|
44 |
|
Linezolid |
Approved, Investigational |
Phase 3 |
|
165800-03-3 |
441401 |
Synonyms:
Linezolid
Linezolide
Linezolidum
N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide
|
N-((3-(3-Fluoro-4-morpholinylphenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide
PNU-100766|PNU100766|U-100,766|U-100766|ZLD|Zyvox®
U-100766
Zyvox
|
|
45 |
|
Acetazolamide |
Approved, Vet_approved |
Phase 3 |
|
59-66-5, 1424-27-7 |
1986 |
Synonyms:
2-Acetylamino-1,3,4-thiadiazole-5-sulfonamide
2-Acetylamino-1,3,4-thiadiazole-5-sulphonamide
5-ACETAMIDO-1,3,4-thiadiazole-2-sulfonamide
5-ACETAMIDO-1,3,4-thiadiazole-2-sulphonamide
5-Acetylamino-1,3,4-thiadiazole-2-sulfonamide
5-Acetylamino-1,3,4-thiadiazole-2-sulphonamide
Acetadiazol
Acetamidothiadiazolesulfonamide
Acetamox
Acetazolam
Acetazolamid
Acetazolamida
ACETAZOLAMIDE
ACÉTAZOLAMIDE
ACETAZOLAMIDE 250MG
Acetazolamide apotex brand
Acetazolamide chiesi brand
Acetazolamide dioptic brand
Acetazolamide grin brand
Acetazolamide icn brand
Acetazolamide jumer brand
Acetazolamide llorens brand
Acetazolamide medphano brand
Acetazolamide novopharm brand
Acetazolamide orion brand
Acetazolamide Sodium
Acetazolamide sodium, (sterile)
Acetazolamide wassermann brand
Acetazolamide, monosodium salt
Acetazolamidum
Acetazolamine
Acetazoleamide
Acetozalamide
Ak zol
Ak-zol
AkZol
Apo acetazolamide
Apo-acetazolamide
ApoAcetazolamide
Apotex brand OF acetazolamide
Atenezol
Carbonic anhydrase inhibitor 6063
Chiesi brand OF acetazolamide
Ciba vision brand OF acetazolamide
Cidamex
Cyanamid brand OF acetazolamide preparation
Dazamide
Defiltran
Défiltran
Dehydratin
Diacarb
Diakarb
|
Diamox
Diamox Sequels
DIAMOX SR
Diamox®
Didoc
Diluran
Dioptic brand OF acetazolamide
Diuramid
Diuramide
Diureticum-Holzinger
Diuriwas
Diutazol
Donmox
Duiramid
Edemox
Eumicton
EYTAZOX
Fonurit
Glauconox
Glaupax
Glupax
Grin brand OF acetazolamide
Huma zolamide
Huma-zolamide
HumaZolamide
ICN brand OF acetazolamide
Jumer brand OF acetazolamide
L 579486
Lederle brand OF acetazolamide preparation
Llorens brand OF acetazolamide
Medphano brand OF acetazolamide
Monosodium salt acetazolamide
N-[5-(Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide
N-[5-(Aminosulfonyl)-1,3,5-thiadiazol-2-yl]acetamide
N-[5-(Aminosulphonyl)-1,3,4-thiadiazol-2-yl]acetamide
N-[5-(Aminosulphonyl)-1,3,5-thiadiazol-2-yl]acetamide
Natrionex
Nephramid
Nephramide
Novopharm brand OF acetazolamide
NSC-145177
Orion brand OF acetazolamide
Phonurit
Sk-Acetazolamide
Storz brand OF acetazolamide preparation
Storzolamide
Théraplix brand OF acetazolamide preparation
Vetamox
Wassermann brand OF acetazolamide
Whelehan brand OF acetazolamide preparation
Wyeth brand OF acetazolamide preparation
|
|
46 |
|
Immunosuppressive Agents |
|
Phase 3 |
|
|
|
47 |
|
Epoetin Alfa |
|
Phase 3 |
|
|
|
Synonyms:
BINOCRIT
EPO
EPOETIN ALFA
EPOGEN
|
EPREX
ERYTHROPOIETIN PRECURSOR
PROCRIT
|
|
48 |
|
Hematinics |
|
Phase 3 |
|
|
|
49 |
|
Antirheumatic Agents |
|
Phase 3 |
|
|
|
50 |
|
Anti-Inflammatory Agents, Non-Steroidal |
|
Phase 3 |
|
|
|
Interventional clinical trials:
(show top 50)
(show all 320)
# |
Name |
Status |
NCT ID |
Phase |
Drugs |
1 |
Sevoflurane Versus Propofol on Optic Nerve Sheath Diameter During Anesthesia in Steep Trendelenburg Position |
Unknown status |
NCT04289090 |
Phase 4 |
Sevoflurane Inhalant Product;Propofol 10 MG/ML |
2 |
EFFECTS OF IMMEDIATE ARGON LASER PERIPHERAL IRIDOPLASTY Versus CONVENTIONAL SYSTEMIC MEDICAL THERAPY ON OPTIC NERVE HEAD STRUCTURE AND FUNCTION OF ACUTE PRIMARY ANGLE CLOSURE EYES |
Unknown status |
NCT00485238 |
Phase 4 |
Intravenous acetazolamide |
3 |
Citicoline Effect on Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) : Pattern Electroretinography Study |
Completed |
NCT03046693 |
Phase 4 |
Group A Citicoline 1000 mg oral tablet;Group B placebo oral tablet |
4 |
Phase 4 Study of Evaluation of Neural Conduction Along the Visual Pathways Before and After Oral Treatment With Citicoline in Patients With Optic Nerve Diseases |
Completed |
NCT00404729 |
Phase 4 |
Citicoline |
5 |
Effect of Levodopa-Carbidopa on Visual Function in Patients With Recent-Onset Nonarteritic Anterior Ischemic Optic Neuropathy |
Completed |
NCT00432393 |
Phase 4 |
levodopa-carbidopa |
6 |
Dalfampridine Treatment for Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) |
Completed |
NCT01975324 |
Phase 4 |
dalfampridine;Placebo |
7 |
External Natural History Controlled, Open-Label Intervention Study to Assess the Efficacy and Safety of Long-Term Treatment With Raxone® in Leber's Hereditary Optic Neuropathy (LHON) |
Completed |
NCT02774005 |
Phase 4 |
Idebenone |
8 |
Use of Bevacizumab in Trabeculectomy Surgery. A Prospective, 2 Centre, Randomized, Controlled Trial |
Completed |
NCT01166594 |
Phase 4 |
Bevacizumab;Control |
9 |
Change in Optic Nerve Head Blood Flow,Optic Nerve Topography and Diurnal Fluctuation of Intraocular Pressure and Pulsatile Ocular Blood Flow in Glaucoma:Cosopt and Xalatan vs Xalatan Alone |
Completed |
NCT00957190 |
Phase 4 |
Dorzolamide 20 mg and Timolol 5 mg |
10 |
Endocrine Dysfunction and Growth Hormone Deficiency in Children With Optic Nerve Hypoplasia |
Completed |
NCT00140413 |
Phase 4 |
Nutropin AQ |
11 |
Effect of High-Dose Prednisolone (Solu Dacortin®) Treatment on Choroidal and Optic Nerve Head Blood Flow in Humans |
Completed |
NCT00312325 |
Phase 4 |
Prednisolone |
12 |
The Effect of Topical Brimonidine on the Hemodynamics of the Optic Nerve Head and Retinochoroidal Circulation in Patients of Primary Open Angle Glaucoma Using Optical Coherence Tomography Angiography |
Completed |
NCT05474716 |
Phase 4 |
Brimonidine tartrate 0.2% ophthalmic solution |
13 |
To Evaluate the Effect of Ginkgo Biloba Extract on Optic Nerve Head Perfusion |
Not yet recruiting |
NCT04846179 |
Phase 4 |
|
14 |
Prospective Case Crossover Study to Assess Whether PDE5 Inhibitor Exposure in Men Increases the Risk for the Development of Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) |
Terminated |
NCT00867815 |
Phase 4 |
Diagnostic procedures |
15 |
The Effect of High Dose Steroid and Normobaric Oxygen Therapy on Recent Onset Non-arteritic Anterior Ischemic Optic Neuropathy(NAION); a Randomized Clinical Trial |
Unknown status |
NCT02439866 |
Phase 3 |
placebo;Intravenous methylprednisolone;normobaric oxygen with face mask |
16 |
Retrobulbar Triamcinolone Acetonide Injection in the Treatment of Nonarteritic Anterior Ischemic Optic Neuropathy |
Unknown status |
NCT02329288 |
Phase 3 |
Triamcinolone Acetonide;placebo |
17 |
Erythropoietin in Methanol Associated Optic Neuropathy |
Unknown status |
NCT02376881 |
Phase 3 |
Erythropoietin |
18 |
The Role of Optic Nerve Sheath Fenestration in Leukemic Patients Having Increased Intracranial Pressure |
Unknown status |
NCT04431882 |
Phase 2, Phase 3 |
|
19 |
Ischemic Optic Neuropathy Decompression Trial (IONDT) |
Completed |
NCT00000127 |
Phase 3 |
|
20 |
Bioretina Inc Ankara University Technopolis |
Completed |
NCT04877067 |
Phase 3 |
|
21 |
Traumatic Optic Neuropathy Treatment Trial 2; Efficacy of Different Doses of Erythropoietin. A Multicenter, Double Blind RCT |
Completed |
NCT03308448 |
Phase 3 |
Recombinant human erythropoietin |
22 |
Long-term Follow-up of ND4 LHON Subjects Treated With GS010 Ocular Gene Therapy in the RESCUE or REVERSE Phase III Clinical Trials (RESTORE) |
Completed |
NCT03406104 |
Phase 3 |
|
23 |
A Randomized, Double-blind, Placebo-controlled Trial of Curcumin in Leber's Hereditary Optic Neuropathy (LHON) |
Completed |
NCT00528151 |
Phase 3 |
curcumin |
24 |
Effect of Bosentan in Patients With Non Arteritic Ischemic Optic Neuropathy |
Recruiting |
NCT02377271 |
Phase 3 |
bosentan;placebo |
25 |
A Phase 1/2/3, Multi-center, Two-part Clinical Trial to Evaluate the Safety and Efficacy of Gene Therapy for Leber's Hereditary Optic Neuropathy (LHON) Associated With ND4 Mutation |
Recruiting |
NCT04912843 |
Phase 2, Phase 3 |
NR082 injection |
26 |
Study of Efficacy of Befizal® 200 mg for the Treatment of Leber Hereditary Optic Neuropathy |
Recruiting |
NCT04561466 |
Phase 2, Phase 3 |
Béfizal |
27 |
Optic Nerve Sheath Diameter (ONSD): A New Modality to Assess Postoperative Agitation After a Single Bolus of Dexmedetomidine Versus Nalbuphine in Children With Cleft Palate Repair |
Recruiting |
NCT04928391 |
Phase 3 |
Dexmedetomidine;Nalbuphine |
28 |
Efficacy and Safety of Bilateral Intravitreal Injection of GS010: A Randomized, Double-Masked, Placebo-Controlled Trial in Subjects Affected With G11778A ND4 Leber Hereditary Optic Neuropathy for Up to One Year |
Active, not recruiting |
NCT03293524 |
Phase 3 |
Placebo |
29 |
A Single Intravitreal Injection of rAAV2-ND4 for the Treatment of Leber's Hereditary Optic Neuropathy |
Active, not recruiting |
NCT03153293 |
Phase 2, Phase 3 |
rAAV2-ND4 |
30 |
Sedation of Ventilated Traumatic Brain Injury Patients With Midazolam Alone Versus Combination With Dexmedetomidine or Magnesium Sulfate; Monitored by Ultrasonograghic Optic Nerve Sheath Diameter |
Not yet recruiting |
NCT05340803 |
Phase 3 |
midazolam;dexmedetomidine;magnesium sulfate |
31 |
A Phase 2/3, Randomized, Double-Masked, Sham-Controlled Trial of QPI-1007 Delivered By Single or Multi-Dose Intravitreal Injection(s) to Subjects With Acute Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) |
Terminated |
NCT02341560 |
Phase 2, Phase 3 |
QPI-1007 Injection - 1.5 mg;QPI-1007 Injection - 3.0 mg |
32 |
Prospective Study Of Ophthalmologic Function In Patients Receiving Linezolid For Six Weeks Or Greater |
Terminated |
NCT00359632 |
Phase 3 |
Zyvox - linezolid;Matched control |
33 |
Randomized Trial of Medical Therapy (MT) vs. MT Plus Optic Nerve Sheath Fenestration vs. MT Plus Ventriculoperitoneal Cerebrospinal Fluid Shunting in Subjects With Idiopathic Intracranial Hypertension and Moderate to Severe Visual Loss |
Terminated |
NCT03501966 |
Phase 3 |
Acetazolamide |
34 |
Study With Idebenone in Patients With Chronic Vision Loss Due to Leber's Hereditary Optic Neuropathy (LHON) |
Withdrawn |
NCT01495715 |
Phase 3 |
Idebenone;Placebo |
35 |
A Randomized Phase 3 Study of Antineoplastons A10 and AS2-1 vs. Temozolomide in Subjects With Recurrent and / or Progressive Optic Pathway Glioma After Carboplatin or Cisplatin Therapy |
Withdrawn |
NCT01260103 |
Phase 3 |
Temozolomide;ANP Therapy |
36 |
Scientific Title: Efficacy of Oral Prednisolone and Erythropoietin Injection in Treatment of Acute Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) |
Unknown status |
NCT03715881 |
Phase 2 |
Oral prednisolone administration 50 mg;Intravenous Erythropoietin injection |
37 |
Intravitreal Bevacizumab for Treatment of the Second Eye With Non-Arteritic Ischemic Optic Neuropathy |
Unknown status |
NCT00813059 |
Phase 2 |
Intra-vitreal injection of bevacizumab (1.25mg/0.05ml) |
38 |
Prospective, Unicentric, Randomized, Parallel, Double-blind, Placebo-controlled Phase II Clinical Trial to Evaluate Intravenous Infusion of Prostaglandins as Therapy in Patients With Anterior Non-arteritic Ischemic Optic Neuropathy |
Unknown status |
NCT03851562 |
Phase 2 |
Alprostadil 20 micrograms;Placebo |
39 |
Comparison of Intravitreal Bevacizumab and Triamcinolone With Placebo in Acute Nonarteritic Anterior Ischemic Optic Neuropathy |
Unknown status |
NCT01330524 |
Phase 1, Phase 2 |
Avastin and Triamcinolone |
40 |
Treatment of Optic Neuropathies Using Autologous Bone-Marrow Derived Clusters of Differentiation (CD) 34+, 133+, and 271+ Stem Cells: A Pilot Study |
Unknown status |
NCT02638714 |
Phase 1, Phase 2 |
|
41 |
Trial of Cyclosporine in the Acute Phase of Leber Hereditary Optic Neuropathy |
Unknown status |
NCT02176733 |
Phase 2 |
cyclosporine |
42 |
Study the Safety and Efficacy of Bone Marrow Derived Autologous Cells for the Treatment of Optic Nerve Disease. It is Self Funded (Patients' Own Funding) Clinical Trial |
Unknown status |
NCT01834079 |
Phase 1, Phase 2 |
|
43 |
Treatment of Patients With Optic Nerve Damage Patients Using Electrostimulation: a Home Stimulation Study |
Unknown status |
NCT04010994 |
Phase 1, Phase 2 |
|
44 |
A Preliminary Double Blind Clinical Study, Efficacy Study of RPh201 Treatment of Ischemic Optic Neuropathy (ION). |
Completed |
NCT02045212 |
Phase 2 |
RPh201;Placebo |
45 |
Neurotomy of Optic Nerve in Non-Arthritic Anterior Ischemic Optic Neuropathy |
Completed |
NCT00372021 |
Phase 1, Phase 2 |
|
46 |
An Open Label Dose Escalation Clinical Trial to Evaluate the Safety and the Tolerability of GS010 (rAAV2/2-ND4) in Patients With Leber Hereditary Optic Neuropathy Due to Mutations in the Mitochondrial NADH Dehydrogenase 4 Gene |
Completed |
NCT02064569 |
Phase 1, Phase 2 |
|
47 |
A Double-Blind, Randomised, Placebo-Controlled Study of the Efficacy, Safety and Tolerability of Idebenone in the Treatment of Patients With Leber's Hereditary Optic Neuropathy |
Completed |
NCT00747487 |
Phase 2 |
Idebenone;Placebo |
48 |
A Prospective, Randomized, Double-Masked, Vehicle Controlled, Phase 2 Clinical Study to Evaluate the Safety, Tolerability and Efficacy of Elamipretide Topical Ophthalmic Solution in Subjects With Leber's Hereditary Optic Neuropathy (LHON) |
Completed |
NCT02693119 |
Phase 2 |
elamipretide (MTP-131) 1% topical ophthalmic solution;Vehicle topical ophthalmic solution |
49 |
Evaluation of the Effect of Subcutaneous Injection of Erythropoietin on Visual Functions in Patients With Late Onset Optic Neuropathy |
Completed |
NCT04469777 |
Phase 1, Phase 2 |
erythropoietin |
50 |
Study of Visual Recovery After Erythropoietin (EPO) Injection, in Patients With Traumatic Optic Neuropathy (TON) |
Completed |
NCT01783847 |
Phase 1, Phase 2 |
Recombinant human erythropoietin (EPO);Methyl prednisolone |
|