MCID: ORL006
MIFTS: 16

Oral Mucosa Leukoplakia

Categories: Oral diseases

Aliases & Classifications for Oral Mucosa Leukoplakia

MalaCards integrated aliases for Oral Mucosa Leukoplakia:

Name: Oral Mucosa Leukoplakia 12 15
Leukoplakia of Buccal Mucosa 73
Leukoplakia, Oral 73

Classifications:



External Ids:

Disease Ontology 12 DOID:9655
ICD10 33 K13.2 K13.21
ICD9CM 35 528.6

Summaries for Oral Mucosa Leukoplakia

MalaCards based summary : Oral Mucosa Leukoplakia, also known as leukoplakia of buccal mucosa, is related to hellp syndrome. An important gene associated with Oral Mucosa Leukoplakia is OAT (Ornithine Aminotransferase), and among its related pathways/superpathways is Fluid shear stress and atherosclerosis. Affiliated tissues include tongue, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Oral Mucosa Leukoplakia

Diseases related to Oral Mucosa Leukoplakia via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 hellp syndrome 9.0 EDN1 GSTP1

Symptoms & Phenotypes for Oral Mucosa Leukoplakia

GenomeRNAi Phenotypes related to Oral Mucosa Leukoplakia according to GeneCards Suite gene sharing:

26 (show all 13)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-107 9.83 GSTP1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-113 9.83 OAT
3 Increased shRNA abundance (Z-score > 2) GR00366-A-130 9.83 OAT GSTP1
4 Increased shRNA abundance (Z-score > 2) GR00366-A-133 9.83 GSTP1
5 Increased shRNA abundance (Z-score > 2) GR00366-A-159 9.83 EDN1 GSTP1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-194 9.83 OAT
7 Increased shRNA abundance (Z-score > 2) GR00366-A-2 9.83 EDN1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.83 OAT
9 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.83 EDN1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.83 EDN1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-70 9.83 EDN1
12 Increased shRNA abundance (Z-score > 2) GR00366-A-88 9.83 OAT EDN1
13 Increased shRNA abundance (Z-score > 2) GR00366-A-9 9.83 GSTP1

Drugs & Therapeutics for Oral Mucosa Leukoplakia

Search Clinical Trials , NIH Clinical Center for Oral Mucosa Leukoplakia

Genetic Tests for Oral Mucosa Leukoplakia

Anatomical Context for Oral Mucosa Leukoplakia

MalaCards organs/tissues related to Oral Mucosa Leukoplakia:

41
Tongue

Publications for Oral Mucosa Leukoplakia

Articles related to Oral Mucosa Leukoplakia:

# Title Authors Year
1
Leukoplakia of buccal mucosa with transformation into spindle cell carcinoma: A rare case report. ( 28479698 )
2017

Variations for Oral Mucosa Leukoplakia

Expression for Oral Mucosa Leukoplakia

Search GEO for disease gene expression data for Oral Mucosa Leukoplakia.

Pathways for Oral Mucosa Leukoplakia

Pathways related to Oral Mucosa Leukoplakia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.77 EDN1 GSTP1

GO Terms for Oral Mucosa Leukoplakia

Biological processes related to Oral Mucosa Leukoplakia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to amino acid GO:0043200 9.16 EDN1 GSTP1
2 cellular response to glucocorticoid stimulus GO:0071385 8.96 EDN1 GSTP1
3 negative regulation of nitric-oxide synthase biosynthetic process GO:0051771 8.62 EDN1 GSTP1

Sources for Oral Mucosa Leukoplakia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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