MCID: ORB002
MIFTS: 17

Orbit Embryonal Rhabdomyosarcoma

Categories: Bone diseases, Cancer diseases, Fetal diseases

Aliases & Classifications for Orbit Embryonal Rhabdomyosarcoma

MalaCards integrated aliases for Orbit Embryonal Rhabdomyosarcoma:

Name: Orbit Embryonal Rhabdomyosarcoma 12 15
Embryonal Rhabdomyosarcoma of the Orbit 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3258
NCIt 50 C6246
UMLS 73 C1335127

Summaries for Orbit Embryonal Rhabdomyosarcoma

MalaCards based summary : Orbit Embryonal Rhabdomyosarcoma, also known as embryonal rhabdomyosarcoma of the orbit, is related to embryonal rhabdomyosarcoma and rhabdomyosarcoma. An important gene associated with Orbit Embryonal Rhabdomyosarcoma is MB (Myoglobin). Affiliated tissues include bone.

Related Diseases for Orbit Embryonal Rhabdomyosarcoma

Diseases related to Orbit Embryonal Rhabdomyosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 embryonal rhabdomyosarcoma 10.5
2 rhabdomyosarcoma 10.4
3 neurofibromatosis, type i 9.9
4 neurofibromatosis, type iv, of riccardi 9.9
5 sarcoma 9.9
6 soft tissue sarcoma 9.9
7 orbit rhabdomyosarcoma 9.2 MB NF1
8 malignant triton tumor 9.0 MB NF1

Graphical network of the top 20 diseases related to Orbit Embryonal Rhabdomyosarcoma:



Diseases related to Orbit Embryonal Rhabdomyosarcoma

Symptoms & Phenotypes for Orbit Embryonal Rhabdomyosarcoma

Drugs & Therapeutics for Orbit Embryonal Rhabdomyosarcoma

Search Clinical Trials , NIH Clinical Center for Orbit Embryonal Rhabdomyosarcoma

Genetic Tests for Orbit Embryonal Rhabdomyosarcoma

Anatomical Context for Orbit Embryonal Rhabdomyosarcoma

MalaCards organs/tissues related to Orbit Embryonal Rhabdomyosarcoma:

41
Bone

Publications for Orbit Embryonal Rhabdomyosarcoma

Articles related to Orbit Embryonal Rhabdomyosarcoma:

(show all 11)
# Title Authors Year
1
Corrigendum: Ermoian RP, Breneman J, Walterhouse DO, etA al. 45A Gy is not sufficient radiotherapy dose for Group III orbital embryonal rhabdomyosarcoma after less than complete response to 12A weeks of ARST0331 chemotherapy. Pediatr Blood Cancer. 2017;64:E26540. https://doi.org/10.1002/pbc.26540. ( 29679530 )
2018
2
45 Gy is not sufficient radiotherapy dose for Group III orbital embryonal rhabdomyosarcoma after less than complete response to 12 weeks of ARST0331 chemotherapy: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group. ( 28548706 )
2017
3
Orbital embryonal rhabdomyosarcoma with metastasis in a young dog. ( 22304975 )
2012
4
Detection of bone metastases in initial staging of orbital embryonal rhabdomyosarcoma by fluorodeoxyglucose positron emission tomography/computed tomography. ( 23487301 )
2011
5
[Two cases of orbital embryonal rhabdomyosarcoma with chromosome aberration]. ( 20432963 )
2010
6
A strategy to avoid facial mutilation in orbital embryonal rhabdomyosarcoma. ( 20143115 )
2010
7
Orbital embryonal rhabdomyosarcoma in association with neurofibromatosis type 1. ( 17413633 )
2007
8
Orbital embryonal rhabdomyosarcoma in Karachi (1998-2002). ( 15623182 )
2004
9
Loss of heterozygosity on the long arm of chromosome 11 in orbital embryonal rhabdomyosarcoma (OERMS): a microsatellite study of seven cases. ( 12048708 )
1998
10
Findings of magnetic resonance and colour-flow Doppler imaging of orbital embryonal rhabdomyosarcoma. ( 8193970 )
1994
11
Orbital embryonal rhabdomyosarcoma and intracranial schwannoma. ( 314794 )
1979

Variations for Orbit Embryonal Rhabdomyosarcoma

Cosmic variations for Orbit Embryonal Rhabdomyosarcoma:

9
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM562 NRAS soft tissue,orbit,rhabdomyosarcoma,embryonal c.34G>T p.G12C 1:114716127-114716127 9
2 COSM496 HRAS soft tissue,orbit,rhabdomyosarcoma,embryonal c.181C>A p.Q61K 11:533875-533875 9
3 COSM143842 ALK soft tissue,orbit,rhabdomyosarcoma,embryonal c.3673G>A p.D1225N 2:29214054-29214054 9
4 COSM123649 soft tissue,orbit,rhabdomyosarcoma,embryonal c.181C>A p.Q61K 11:533875-533875 9
5 COSM6949226 soft tissue,orbit,rhabdomyosarcoma,embryonal c.1337G>A p.C446Y 5:56871945-56871945 9

Expression for Orbit Embryonal Rhabdomyosarcoma

Search GEO for disease gene expression data for Orbit Embryonal Rhabdomyosarcoma.

Pathways for Orbit Embryonal Rhabdomyosarcoma

GO Terms for Orbit Embryonal Rhabdomyosarcoma

Biological processes related to Orbit Embryonal Rhabdomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 heart development GO:0007507 8.96 MB NF1
2 response to hypoxia GO:0001666 8.62 MB NF1

Sources for Orbit Embryonal Rhabdomyosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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