Aliases & Classifications for Orbital Cellulitis

MalaCards integrated aliases for Orbital Cellulitis:

Name: Orbital Cellulitis 12 45 15 17 74

Classifications:



External Ids:

Disease Ontology 12 DOID:11234
ICD9CM 36 376.01
MeSH 45 D054517
NCIt 51 C99000
ICD10 34 H05.01
UMLS 74 C0149507

Summaries for Orbital Cellulitis

Disease Ontology : 12 An acute orbital inflammation that is characterized by painful orbital mass and has symptom eyelid edema, has symptom erythema, has symptom chemiosis, has symptom proptosis, has symptom blurred vision, has symptom headache, has symptom fever and has symptom double vision.

MalaCards based summary : Orbital Cellulitis is related to pleural empyema and cavernous sinus thrombosis, and has symptoms including fever, headache and erythema. An important gene associated with Orbital Cellulitis is RHNO1 (RAD9-HUS1-RAD1 Interacting Nuclear Orphan 1), and among its related pathways/superpathways is NF-kappaB Signaling. Affiliated tissues include eye, brain and bone, and related phenotypes are cardiovascular system and mortality/aging

Wikipedia : 77 Orbital cellulitis is inflammation of eye tissues behind the orbital septum. It is most commonly caused... more...

Related Diseases for Orbital Cellulitis

Diseases related to Orbital Cellulitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 141)
# Related Disease Score Top Affiliating Genes
1 pleural empyema 30.5 CRP PGBD1
2 cavernous sinus thrombosis 30.5 PGBD1 RHNO1 SDC1
3 dental abscess 30.3 BIN1 CRP
4 sphenoid sinusitis 30.2 CRP NT5C2 RHNO1
5 necrotizing fasciitis 30.1 IL1RN LTA
6 subdural empyema 30.0 CRP PGBD1
7 spondylitis 29.9 CRP IL1RN LTA
8 cellulitis 11.2
9 sinusitis 10.5
10 intracranial sinus thrombosis 10.4 PGBD1 RHNO1
11 mastoiditis 10.4 CRP RHNO1
12 thrombosis 10.4
13 retinoblastoma 10.4
14 intracranial abscess 10.4 BIN1 CRP
15 parasitic ichthyosporea infectious disease 10.3 NCAM1 RHNO1
16 rhinosporidiosis 10.3 NCAM1 RHNO1
17 rhinoscleroma 10.3 NCAM1 RHNO1
18 ethmoid sinusitis 10.3 CRP RHNO1
19 pericoronitis 10.3 CRP NCAM1
20 orbital disease 10.3 CRP PGBD1 RHNO1
21 endophthalmitis 10.3
22 cryopyrin-associated periodic syndrome 10.3 CRP IL1RN
23 intestinal perforation 10.3 CRP NCAM1
24 mitochondrial disorders 10.3 COX5A OPA1
25 listeria meningitis 10.3 LTA RHNO1
26 strabismus 10.3
27 lymphoma 10.3
28 dacryoadenitis 10.3
29 dacryocystitis 10.3
30 hyper-igd syndrome 10.3 CRP IL1RN
31 schnitzler syndrome 10.3 CRP IL1RN
32 panophthalmitis 10.3
33 mechanical strabismus 10.3
34 cartilage disease 10.2 CRP IL1RN
35 cecal disease 10.2 CRP HCK
36 cataract 10.2
37 melanoma 10.2
38 acute cholangitis 10.2 CRP IL1RN NT5C2
39 osteomyelitis 10.2
40 haemophilus influenzae 10.2
41 pericardium disease 10.1 CRP IL1RN
42 juvenile rheumatoid arthritis 10.1 CRP IL1RN LTA
43 myositis 10.1
44 scleritis 10.1
45 conjunctivitis 10.1
46 chronic maxillary sinusitis 10.1 IRF6 PDPN RHNO1
47 keratitis, hereditary 10.0
48 retinal detachment 10.0
49 yemenite deaf-blind hypopigmentation syndrome 10.0
50 acute dacryocystitis 10.0

Comorbidity relations with Orbital Cellulitis via Phenotypic Disease Network (PDN):


Acute Cystitis Acute Dacryocystitis
Dacryocystitis Hypertension, Essential

Graphical network of the top 20 diseases related to Orbital Cellulitis:



Diseases related to Orbital Cellulitis

Symptoms & Phenotypes for Orbital Cellulitis

Symptoms:

12
  • fever
  • headache
  • erythema
  • proptosis
  • blurred vision
  • double vision
  • eyelid edema
  • chemiosis

MGI Mouse Phenotypes related to Orbital Cellulitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.61 BIN1 CRP HCK IL1RN KIDINS220 LTA
2 mortality/aging MP:0010768 9.4 BIN1 HCK IL1RN IRF6 KIDINS220 LTA

Drugs & Therapeutics for Orbital Cellulitis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Fast Magnetic Resonance Imaging as Compared to Computed Tomography Scan in Pediatric Orbital Cellulitis Imaging Unknown status NCT02711436 Not Applicable
2 SLlt Stent II Lacrimal Stent for the Treatment of Nasolacrimal Duct Obstruction Not yet recruiting NCT03705000 Not Applicable
3 The Use of Prophylactic Antibiotics in Isolated Blowout Fractures Withdrawn NCT01504568 Not Applicable

Search NIH Clinical Center for Orbital Cellulitis

Cochrane evidence based reviews: orbital cellulitis

Genetic Tests for Orbital Cellulitis

Anatomical Context for Orbital Cellulitis

MalaCards organs/tissues related to Orbital Cellulitis:

42
Eye, Brain, Bone, T Cells, Liver, Colon, Retina

Publications for Orbital Cellulitis

Articles related to Orbital Cellulitis:

(show top 50) (show all 504)
# Title Authors Year
1
Trend of surgery for orbital cellulitis: An analysis of state inpatient databases. ( 31050824 )
2019
2
A Case of Pseudomonas Orbital Cellulitis Following Glaucoma Device Implantation. ( 30234747 )
2019
3
Epidemiological characteristics of orbital cellulitis among adult population in the Split region, Croatia. ( 30374774 )
2019
4
Absorbable Implant Foreign Body Reaction Masquerading as Orbital Cellulitis. ( 30439723 )
2019
5
Pediatric preseptal and orbital cellulitis: A 10-year experience. ( 30772617 )
2019
6
Fifteen-minute consultation: Preseptal and orbital cellulitis. ( 29934359 )
2019
7
Acute dacryocystitis complicated by orbital cellulitis and loss of vision: A case report and review of the literature. ( 30118963 )
2018
8
Spontaneous Rupture of Lacrimal Gland Pleomorphic Adenoma: Pivotal Role in Masquerading Orbital Cellulitis. ( 29049099 )
2018
9
Septic Cavernous Sinus Thrombosis Associated With Orbital Cellulitis: A Report of 6 Cases and Review of Literature. ( 30320718 )
2018
10
C-reactive protein may be useful to differentiate idiopathic orbital inflammation and orbital cellulitis in cases with acute eyelid erythema and edema. ( 29983541 )
2018
11
Clinical Outcomes in Children With Orbital Cellulitis and Radiographic Globe Tenting. ( 29990314 )
2018
12
Extra-Ocular Cysticercosis Mimicking Orbital Cellulitis. ( 30060802 )
2018
13
Scleritis, keratitis, and orbital cellulitis: isolated ocular manifestation of systemic lupus erythematosus. ( 30092731 )
2018
14
Orbital cellulitis with choroidal detachment following strabismus surgery in an adult. ( 30171895 )
2018
15
Necrotizing Orbital Cellulitis Secondary to Odontogenic Streptococcus constellatus. ( 30198981 )
2018
16
Elevated Optic Disc Height and Increased Optic Nerve Sheath Diameter on Bedside Ultrasound in a Pediatric Patient With Orbital Cellulitis: More Than Meets the Eye. ( 30253955 )
2018
17
Orbital Cellulitis and Secondary Angle Closure: A Rare Presentation of Choroidal Melanoma. ( 30320095 )
2018
18
Klebsiella pneumoniae Orbital Cellulitis: Clinical Manifestations and Outcomes in a Tertiary Medical Center in Taiwan. ( 30370149 )
2018
19
Emergency management: orbital cellulitis. ( 30487680 )
2018
20
Choroidal melanoma masquerading as orbital cellulitis. ( 30567222 )
2018
21
A rare case of orbital granulomatous inflammation from explosive hydraulic oil masquerading as orbital cellulitis. ( 29053030 )
2018
22
Hyaluronidase allergy mimicking orbital cellulitis. ( 29053033 )
2018
23
Clinical Course of Preseptal and Orbital Cellulitis in 50 Immunocompromised Patients with Cancer. ( 29128228 )
2018
24
Variation in Care and Clinical Outcomes in Children Hospitalized With Orbital Cellulitis. ( 29208694 )
2018
25
Orbital cellulitis. ( 29248536 )
2018
26
Temporal Expression of Genes in Biofilm-Forming Ocular Candida albicans Isolated From Patients With Keratitis and Orbital Cellulitis. ( 29372251 )
2018
27
Orbital Cellulitis from an Orbital Compressed Air and Diesel Explosion Injury. ( 29611376 )
2018
28
Clostridium perfringens panophthalmitis and orbital cellulitis: a case report. ( 29631556 )
2018
29
A case report of orbital Langerhans cell histiocytosis presenting as a orbital cellulitis. ( 29643005 )
2018
30
Orbital cellulitis secondary to a fungal sinusitis caused by Scopulariopsis: The first case in Tunisia. ( 29709267 )
2018
31
Orbital Cellulitis-When Computed Tomography Imaging Is Falsely Reassuring. ( 29768298 )
2018
32
Trigeminal Trophic Syndrome Leading to Orbital Cellulitis. ( 29849238 )
2018
33
Management of pediatric orbital cellulitis: A systematic review. ( 29859573 )
2018
34
Nasal septal abscess as a sequela of orbital cellulitis: An uncommon presentation. ( 29899988 )
2018
35
Systemic corticosteroids may be beneficial for managing severe or refractory orbital cellulitis in children. ( 29920768 )
2018
36
Molecular Characterization of Staphylococcus aureus Isolates From Children With Periorbital or Orbital Cellulitis. ( 28575438 )
2018
37
Acute Sickle Cell Orbitopathy Masquerading as Orbital Cellulitis. ( 28816800 )
2018
38
Intravenous Steroids With Antibiotics on Admission for Children With Orbital Cellulitis. ( 28369021 )
2018
39
Necrotic intraocular retinoblastoma associated with orbital cellulitis. ( 28254446 )
2018
40
Saksenaea vasiformis Orbital Cellulitis in an Immunocompetent Child Treated With Posaconazole. ( 29522137 )
2018
41
Orbital apex syndrome from bacterial sinusitis without orbital cellulitis. ( 29468204 )
2018
42
Orbital Cellulitis, Cavernous Sinus Thrombosis, Internal Jugular Vein Thrombus, and Clival Osteomyelitis Secondary to Acute Sinusitis. ( 27983875 )
2017
43
Odontogenic orbital cellulitis associated with cavernous sinus thrombosis and pulmonary embolism: a case report. ( 28629401 )
2017
44
Orbital Cellulitis Presenting as Giant Cell Arteritis: A Case Report. ( 29250759 )
2017
45
Case report of the family transmission of Streptococcus pyogenes orbital cellulitis. ( 29260057 )
2017
46
Lymphoma Maxilla mimicking orbital cellulitis; case report and review of Literature. ( 29634709 )
2017
47
Orbital Perivenous Abscess Complicating the Diagnosis and Management of Orbital Cellulitis. ( 28481768 )
2017
48
Orbital Cellulitis Following Uncomplicated Aqueous Shunt Surgery. ( 28557824 )
2017
49
Paediatric orbital cellulitis and the relationship to underlying sinonasal anatomy on computed tomography. ( 28683847 )
2017
50
Infective Endocarditis Presenting as Bilateral Orbital Cellulitis: An Unusual Case. ( 28721318 )
2017

Variations for Orbital Cellulitis

Expression for Orbital Cellulitis

Search GEO for disease gene expression data for Orbital Cellulitis.

Pathways for Orbital Cellulitis

Pathways related to Orbital Cellulitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.54 HCK IL1RN IRF6 NCAM1 TPT1

GO Terms for Orbital Cellulitis

Biological processes related to Orbital Cellulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.56 CRP HCK IL1RN SDC1
2 negative regulation of apoptotic process GO:0043066 9.26 HCK OPA1 PDPN TPT1
3 lymph node development GO:0048535 9.16 LTA PDPN
4 interferon-gamma-mediated signaling pathway GO:0060333 8.8 HCK IRF6 NCAM1

Sources for Orbital Cellulitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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