Aliases & Classifications for Orbital Cellulitis

MalaCards integrated aliases for Orbital Cellulitis:

Name: Orbital Cellulitis 12 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:11234
ICD10 33 H05.01
ICD9CM 35 376.01
MeSH 44 D054517
NCIt 50 C99000
UMLS 73 C0149507

Summaries for Orbital Cellulitis

Disease Ontology : 12 An acute orbital inflammation that is characterized by painful orbital mass and has symptom eyelid edema, has symptom erythema, has symptom chemiosis, has symptom proptosis, has symptom blurred vision, has symptom headache, has symptom fever and has symptom double vision.

MalaCards based summary : Orbital Cellulitis is related to cavernous sinus thrombosis and necrotizing fasciitis, and has symptoms including fever, erythema and proptosis. An important gene associated with Orbital Cellulitis is RHNO1 (RAD9-HUS1-RAD1 Interacting Nuclear Orphan 1), and among its related pathways/superpathways is NF-kappaB Signaling. Affiliated tissues include eye, brain and bone, and related phenotype is immune system.

Wikipedia : 76 Orbital cellulitis is inflammation of eye tissues behind the orbital septum. It most commonly refers to... more...

Related Diseases for Orbital Cellulitis

Diseases related to Orbital Cellulitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 141)
# Related Disease Score Top Affiliating Genes
1 cavernous sinus thrombosis 30.3 PGBD1 PTCRA RHNO1 SDC1
2 necrotizing fasciitis 30.1 IL1RN LTA
3 dental abscess 30.0 BIN1 CRP
4 subdural empyema 29.9 CRP PGBD1
5 spondylitis 29.8 CRP IL1RN LTA
6 cellulitis 11.1
7 sinusitis 10.5
8 thrombosis 10.4
9 retinoblastoma 10.3
10 endophthalmitis 10.3
11 intracranial sinus thrombosis 10.3 PGBD1 RHNO1
12 strabismus 10.3
13 lymphoma 10.3
14 dacryocystitis 10.3
15 mastoiditis 10.3 CRP RHNO1
16 panophthalmitis 10.2
17 pleural empyema 10.2 CRP PGBD1
18 granulomatous orchitis 10.2 CRP PTCRA
19 intracranial abscess 10.2 BIN1 CRP
20 ethmoid sinusitis 10.2 CRP RHNO1
21 cryopyrin-associated periodic syndrome 10.2 CRP IL1RN
22 orbital disease 10.2 CRP PGBD1 RHNO1
23 hyper-igd syndrome 10.2 CRP IL1RN
24 listeria meningitis 10.2 LTA RHNO1
25 sphenoid sinusitis 10.2 CRP NT5C2 RHNO1
26 schnitzler syndrome 10.2 CRP IL1RN
27 acquired idiopathic sideroblastic anemia 10.2 COX5A TET2
28 folic acid deficiency anemia 10.2 CRP TET2
29 myelodysplastic syndrome with excess blasts 10.2 LTA TET2
30 cataract 10.2
31 acute cholangitis 10.1 CRP IL1RN NT5C2
32 osteomyelitis 10.1
33 melanoma 10.1
34 haemophilus influenzae 10.1
35 chondromalacia 10.1 IL1RN TET2
36 cecal disease 10.1 CRP HCK
37 pericardium disease 10.1 CRP IL1RN
38 juvenile rheumatoid arthritis 10.1 CRP IL1RN LTA
39 gnathomiasis 10.1 PTCRA TET2
40 myositis 10.1
41 scleritis 10.1
42 conjunctivitis 10.1
43 cartilage disease 10.1 CRP IL1RN TET2
44 chronic maxillary sinusitis 10.1 IRF6 PDPN RHNO1
45 retinal detachment 10.0
46 acute dacryocystitis 10.0
47 central retinal artery occlusion 10.0
48 influenza 10.0
49 retinal artery occlusion 10.0
50 mucormycosis 10.0

Comorbidity relations with Orbital Cellulitis via Phenotypic Disease Network (PDN):


Acute Cystitis Acute Dacryocystitis
Dacryocystitis Hypertension, Essential

Graphical network of the top 20 diseases related to Orbital Cellulitis:



Diseases related to Orbital Cellulitis

Symptoms & Phenotypes for Orbital Cellulitis

Symptoms:

12
  • fever
  • erythema
  • proptosis
  • blurred vision
  • headache
  • double vision
  • eyelid edema
  • chemiosis

MGI Mouse Phenotypes related to Orbital Cellulitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.32 BIN1 CRP HCK IL1RN LTA OPTN

Drugs & Therapeutics for Orbital Cellulitis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Fast Magnetic Resonance Imaging as Compared to Computed Tomography Scan in Pediatric Orbital Cellulitis Imaging Unknown status NCT02711436 Not Applicable
2 SLlt Stent II Lacrimal Stent for the Treatment of Nasolacrimal Duct Obstruction Recruiting NCT03705000 Not Applicable
3 The Use of Prophylactic Antibiotics in Isolated Blowout Fractures Withdrawn NCT01504568 Not Applicable

Search NIH Clinical Center for Orbital Cellulitis

Cochrane evidence based reviews: orbital cellulitis

Genetic Tests for Orbital Cellulitis

Anatomical Context for Orbital Cellulitis

MalaCards organs/tissues related to Orbital Cellulitis:

41
Eye, Brain, Bone, T Cells, Neutrophil, B Cells, Retina

Publications for Orbital Cellulitis

Articles related to Orbital Cellulitis:

(show top 50) (show all 503)
# Title Authors Year
1
Systemic corticosteroids may be beneficial for managing severe or refractory orbital cellulitis in children. ( 29920768 )
2018
2
Management of pediatric orbital cellulitis: A systematic review. ( 29859573 )
2018
3
Orbital Cellulitis ( 29939678 )
2018
4
A case report of orbital Langerhans cell histiocytosis presenting as a orbital cellulitis. ( 29643005 )
2018
5
Orbital cellulitis secondary to a fungal sinusitis caused by Scopulariopsis: The first case in Tunisia. ( 29709267 )
2018
6
Clinical Course of Preseptal and Orbital Cellulitis in 50 Immunocompromised Patients with Cancer. ( 29128228 )
2018
7
Orbital Cellulitis-When Computed Tomography Imaging Is Falsely Reassuring. ( 29768298 )
2018
8
Temporal Expression of Genes in Biofilm-Forming Ocular Candida albicans Isolated From Patients With Keratitis and Orbital Cellulitis. ( 29372251 )
2018
9
Saksenaea vasiformis Orbital Cellulitis in an Immunocompetent Child Treated With Posaconazole. ( 29522137 )
2018
10
Nasal septal abscess as a sequela of orbital cellulitis: An uncommon presentation. ( 29899988 )
2018
11
Fifteen-minute consultation: Preseptal and orbital cellulitis. ( 29934359 )
2018
12
Orbital Cellulitis from an Orbital Compressed Air and Diesel Explosion Injury. ( 29611376 )
2018
13
Clostridium perfringens panophthalmitis and orbital cellulitis: a case report. ( 29631556 )
2018
14
Orbital apex syndrome from bacterial sinusitis without orbital cellulitis. ( 29468204 )
2018
15
Trigeminal Trophic Syndrome Leading to Orbital Cellulitis. ( 29849238 )
2018
16
Variation in Care and Clinical Outcomes in Children Hospitalized With Orbital Cellulitis. ( 29208694 )
2018
17
Acute dacryocystitis complicated by orbital cellulitis and loss of vision: A case report and review of the literature. ( 30118963 )
2018
18
Orbital Cellulitis and Secondary Angle Closure: A Rare Presentation of Choroidal Melanoma. ( 30320095 )
2018
19
Septic Cavernous Sinus Thrombosis Associated With Orbital Cellulitis: A Report of 6 Cases and Review of Literature. ( 30320718 )
2018
20
Klebsiella pneumoniae Orbital Cellulitis: Clinical Manifestations and Outcomes in a Tertiary Medical Center in Taiwan. ( 30370149 )
2018
21
Epidemiological characteristics of orbital cellulitis among adult population in the Split region, Croatia. ( 30374774 )
2018
22
Absorbable Implant Foreign Body Reaction Masquerading as Orbital Cellulitis. ( 30439723 )
2018
23
Emergency management: orbital cellulitis. ( 30487680 )
2018
24
C-reactive protein may be useful to differentiate idiopathic orbital inflammation and orbital cellulitis in cases with acute eyelid erythema and edema. ( 29983541 )
2018
25
Clinical Outcomes in Children With Orbital Cellulitis and Radiographic Globe Tenting. ( 29990314 )
2018
26
Extra-Ocular Cysticercosis Mimicking Orbital Cellulitis. ( 30060802 )
2018
27
Scleritis, keratitis, and orbital cellulitis: isolated ocular manifestation of systemic lupus erythematosus. ( 30092731 )
2018
28
Orbital cellulitis with choroidal detachment following strabismus surgery in an adult. ( 30171895 )
2018
29
Necrotizing Orbital Cellulitis Secondary to Odontogenic Streptococcus constellatus. ( 30198981 )
2018
30
A Case of Pseudomonas Orbital Cellulitis Following Glaucoma Device Implantation. ( 30234747 )
2018
31
Elevated Optic Disc Height and Increased Optic Nerve Sheath Diameter on Bedside Ultrasound in a Pediatric Patient With Orbital Cellulitis: More Than Meets the Eye. ( 30253955 )
2018
32
Orbital cellulitis and brain abscess - rare complications of maxillo-spheno-ethmoidal rhinosinusitis. ( 29450387 )
2017
33
Orbital Cellulitis Following Orbital Blow-out Fracture. ( 28806382 )
2017
34
Acute Sickle Cell Orbitopathy Masquerading as Orbital Cellulitis. ( 28816800 )
2017
35
Hyaluronidase allergy mimicking orbital cellulitis. ( 29053033 )
2017
36
Case report of the family transmission of<i>Streptococcus pyogenes</i>orbital cellulitis. ( 29260057 )
2017
37
Orbital Cellulitis Presenting as Giant Cell Arteritis: A Case Report. ( 29250759 )
2017
38
Orbital Cellulitis Following Uncomplicated Aqueous Shunt Surgery. ( 28557827 )
2017
39
A rare case of orbital granulomatous inflammation from explosive hydraulic oil masquerading as orbital cellulitis. ( 29053030 )
2017
40
Clinical profile and outcomes of management of orbital cellulitis in Upper Egypt. ( 28275981 )
2017
41
Extranodal natural killer/T-cell lymphoma presenting as orbital cellulitis. ( 28194321 )
2017
42
Reply re: &amp;quot;Intravenous Steroids With Antibiotics on Admission for Children With Orbital Cellulitis&amp;quot;. ( 28891916 )
2017
43
Lymphoma Maxilla mimicking orbital cellulitis; case report and review of Literature. ( 29634709 )
2017
44
Infective Endocarditis Presenting as Bilateral Orbital Cellulitis: An Unusual Case. ( 28721318 )
2017
45
Re: &amp;quot;Intravenous Steroids With Antibiotics on Admission for Children With Orbital Cellulitis&amp;quot;. ( 28891915 )
2017
46
Orbital cellulitis from facial tissue fillers. ( 28186379 )
2017
47
Orbital Cellulitis Following Uncomplicated Aqueous Shunt Surgery. ( 28557824 )
2017
48
Intravenous Steroids With Antibiotics on Admission for Children With Orbital Cellulitis. ( 28369021 )
2017
49
SUBTENON AMIKACIN INJECTION FOR THE TREATMENT OF NOCARDIA ASTEROIDES ORBITAL CELLULITIS IN A PATIENT WITH A HISTORY OF SCLERAL BUCKLING. ( 28925928 )
2017
50
Orbital Cellulitis. ( 29248536 )
2017

Variations for Orbital Cellulitis

Expression for Orbital Cellulitis

Search GEO for disease gene expression data for Orbital Cellulitis.

Pathways for Orbital Cellulitis

Pathways related to Orbital Cellulitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.44 HCK IL1RN IRF6 TPT1

GO Terms for Orbital Cellulitis

Biological processes related to Orbital Cellulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.26 CRP HCK IL1RN SDC1
2 lymph node development GO:0048535 8.62 LTA PDPN

Molecular functions related to Orbital Cellulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.55 BIN1 COX5A CRP HCK IL1RN IRF6

Sources for Orbital Cellulitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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