Aliases & Classifications for Orbital Cellulitis

MalaCards integrated aliases for Orbital Cellulitis:

Name: Orbital Cellulitis 12 45 15 17 74

Classifications:



External Ids:

Disease Ontology 12 DOID:11234
ICD9CM 36 376.01
MeSH 45 D054517
NCIt 51 C99000
ICD10 34 H05.01
UMLS 74 C0149507

Summaries for Orbital Cellulitis

Disease Ontology : 12 An acute orbital inflammation that is characterized by painful orbital mass and has symptom eyelid edema, has symptom erythema, has symptom chemiosis, has symptom proptosis, has symptom blurred vision, has symptom headache, has symptom fever and has symptom double vision.

MalaCards based summary : Orbital Cellulitis is related to dental abscess and cavernous sinus thrombosis, and has symptoms including fever, erythema and proptosis. An important gene associated with Orbital Cellulitis is RHNO1 (RAD9-HUS1-RAD1 Interacting Nuclear Orphan 1), and among its related pathways/superpathways is NF-kappaB Signaling. Affiliated tissues include eye, brain and bone, and related phenotypes are cardiovascular system and mortality/aging

Wikipedia : 77 Orbital cellulitis is inflammation of eye tissues behind the orbital septum. It is most commonly caused... more...

Related Diseases for Orbital Cellulitis

Diseases related to Orbital Cellulitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 136)
# Related Disease Score Top Affiliating Genes
1 dental abscess 30.2 BIN1 CRP
2 cavernous sinus thrombosis 30.2 PGBD1 PTCRA RHNO1 SDC1
3 spondylitis 29.9 CRP IL1RN LTA
4 cellulitis 11.2
5 sinusitis 10.5
6 intracranial sinus thrombosis 10.4 PGBD1 RHNO1
7 mastoiditis 10.4 CRP RHNO1
8 thrombosis 10.4
9 granulomatous orchitis 10.4 CRP PTCRA
10 retinoblastoma 10.3
11 parasitic ichthyosporea infectious disease 10.3 NCAM1 RHNO1
12 orbital disease 10.3 CRP PGBD1 RHNO1
13 rhinosporidiosis 10.3 NCAM1 RHNO1
14 sphenoid sinusitis 10.3 CRP NT5C2 RHNO1
15 intracranial abscess 10.3 BIN1 CRP
16 endophthalmitis 10.3
17 rhinoscleroma 10.3 NCAM1 RHNO1
18 pericoronitis 10.3 CRP NCAM1
19 pleural empyema 10.3 CRP PGBD1
20 cryopyrin-associated periodic syndrome 10.3 CRP IL1RN
21 strabismus 10.3
22 lymphoma 10.3
23 dacryocystitis 10.3
24 hyper-igd syndrome 10.3 CRP IL1RN
25 intestinal perforation 10.3 CRP NCAM1
26 panophthalmitis 10.3
27 schnitzler syndrome 10.2 CRP IL1RN
28 pancreatic serous cystadenoma 10.2 NCAM1 PTCRA
29 mitochondrial disorders 10.2 COX5A OPA1
30 cartilage disease 10.2 CRP IL1RN
31 acute cholangitis 10.2 CRP IL1RN NT5C2
32 cataract 10.2
33 melanoma 10.2
34 listeria meningitis 10.2 LTA RHNO1
35 ethmoid sinusitis 10.2 CRP RHNO1
36 osteomyelitis 10.2
37 haemophilus influenzae 10.2
38 neurogenic bowel 10.1 KIDINS220 PTCRA
39 juvenile rheumatoid arthritis 10.1 CRP IL1RN LTA
40 myositis 10.1
41 scleritis 10.1
42 conjunctivitis 10.1
43 chronic maxillary sinusitis 10.1 IRF6 PDPN RHNO1
44 retinal detachment 10.0
45 acute dacryocystitis 10.0
46 central retinal artery occlusion 10.0
47 influenza 10.0
48 retinal artery occlusion 10.0
49 mucormycosis 10.0
50 orbital plasma cell granuloma 10.0

Comorbidity relations with Orbital Cellulitis via Phenotypic Disease Network (PDN):


Acute Cystitis Acute Dacryocystitis
Dacryocystitis Hypertension, Essential

Graphical network of the top 20 diseases related to Orbital Cellulitis:



Diseases related to Orbital Cellulitis

Symptoms & Phenotypes for Orbital Cellulitis

Symptoms:

12
  • fever
  • erythema
  • proptosis
  • blurred vision
  • headache
  • double vision
  • eyelid edema
  • chemiosis

MGI Mouse Phenotypes related to Orbital Cellulitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.61 BIN1 CRP HCK IL1RN KIDINS220 LTA
2 mortality/aging MP:0010768 9.4 BIN1 HCK IL1RN IRF6 KIDINS220 LTA

Drugs & Therapeutics for Orbital Cellulitis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Fast Magnetic Resonance Imaging as Compared to Computed Tomography Scan in Pediatric Orbital Cellulitis Imaging Unknown status NCT02711436 Not Applicable
2 SLlt Stent II Lacrimal Stent for the Treatment of Nasolacrimal Duct Obstruction Recruiting NCT03705000 Not Applicable
3 The Use of Prophylactic Antibiotics in Isolated Blowout Fractures Withdrawn NCT01504568 Not Applicable

Search NIH Clinical Center for Orbital Cellulitis

Cochrane evidence based reviews: orbital cellulitis

Genetic Tests for Orbital Cellulitis

Anatomical Context for Orbital Cellulitis

MalaCards organs/tissues related to Orbital Cellulitis:

42
Eye, Brain, Bone, T Cells, Liver, Colon, Retina

Publications for Orbital Cellulitis

Articles related to Orbital Cellulitis:

(show top 50) (show all 505)
# Title Authors Year
1
Pediatric preseptal and orbital cellulitis: A 10-year experience. ( 30772617 )
2019
2
Systemic corticosteroids may be beneficial for managing severe or refractory orbital cellulitis in children. ( 29920768 )
2018
3
Management of pediatric orbital cellulitis: A systematic review. ( 29859573 )
2018
4
Orbital Cellulitis ( 29939678 )
2018
5
A case report of orbital Langerhans cell histiocytosis presenting as a orbital cellulitis. ( 29643005 )
2018
6
Orbital cellulitis secondary to a fungal sinusitis caused by Scopulariopsis: The first case in Tunisia. ( 29709267 )
2018
7
Clinical Course of Preseptal and Orbital Cellulitis in 50 Immunocompromised Patients with Cancer. ( 29128228 )
2018
8
Orbital Cellulitis-When Computed Tomography Imaging Is Falsely Reassuring. ( 29768298 )
2018
9
Temporal Expression of Genes in Biofilm-Forming Ocular Candida albicans Isolated From Patients With Keratitis and Orbital Cellulitis. ( 29372251 )
2018
10
Saksenaea vasiformis Orbital Cellulitis in an Immunocompetent Child Treated With Posaconazole. ( 29522137 )
2018
11
Nasal septal abscess as a sequela of orbital cellulitis: An uncommon presentation. ( 29899988 )
2018
12
Fifteen-minute consultation: Preseptal and orbital cellulitis. ( 29934359 )
2018
13
Orbital Cellulitis from an Orbital Compressed Air and Diesel Explosion Injury. ( 29611376 )
2018
14
Clostridium perfringens panophthalmitis and orbital cellulitis: a case report. ( 29631556 )
2018
15
Orbital apex syndrome from bacterial sinusitis without orbital cellulitis. ( 29468204 )
2018
16
Trigeminal Trophic Syndrome Leading to Orbital Cellulitis. ( 29849238 )
2018
17
Variation in Care and Clinical Outcomes in Children Hospitalized With Orbital Cellulitis. ( 29208694 )
2018
18
Acute dacryocystitis complicated by orbital cellulitis and loss of vision: A case report and review of the literature. ( 30118963 )
2018
19
Septic Cavernous Sinus Thrombosis Associated With Orbital Cellulitis: A Report of 6 Cases and Review of Literature. ( 30320718 )
2018
20
C-reactive protein may be useful to differentiate idiopathic orbital inflammation and orbital cellulitis in cases with acute eyelid erythema and edema. ( 29983541 )
2018
21
Clinical Outcomes in Children With Orbital Cellulitis and Radiographic Globe Tenting. ( 29990314 )
2018
22
Extra-Ocular Cysticercosis Mimicking Orbital Cellulitis. ( 30060802 )
2018
23
Scleritis, keratitis, and orbital cellulitis: isolated ocular manifestation of systemic lupus erythematosus. ( 30092731 )
2018
24
Orbital cellulitis with choroidal detachment following strabismus surgery in an adult. ( 30171895 )
2018
25
Necrotizing Orbital Cellulitis Secondary to Odontogenic Streptococcus constellatus. ( 30198981 )
2018
26
A Case of Pseudomonas Orbital Cellulitis Following Glaucoma Device Implantation. ( 30234747 )
2018
27
Elevated Optic Disc Height and Increased Optic Nerve Sheath Diameter on Bedside Ultrasound in a Pediatric Patient With Orbital Cellulitis: More Than Meets the Eye. ( 30253955 )
2018
28
Orbital Cellulitis and Secondary Angle Closure: A Rare Presentation of Choroidal Melanoma. ( 30320095 )
2018
29
Klebsiella pneumoniae Orbital Cellulitis: Clinical Manifestations and Outcomes in a Tertiary Medical Center in Taiwan. ( 30370149 )
2018
30
Epidemiological characteristics of orbital cellulitis among adult population in the Split region, Croatia. ( 30374774 )
2018
31
Absorbable Implant Foreign Body Reaction Masquerading as Orbital Cellulitis. ( 30439723 )
2018
32
Emergency management: orbital cellulitis. ( 30487680 )
2018
33
Choroidal melanoma masquerading as orbital cellulitis. ( 30567222 )
2018
34
Orbital cellulitis and brain abscess - rare complications of maxillo-spheno-ethmoidal rhinosinusitis. ( 29450387 )
2017
35
Orbital Cellulitis Following Orbital Blow-out Fracture. ( 28806382 )
2017
36
Acute Sickle Cell Orbitopathy Masquerading as Orbital Cellulitis. ( 28816800 )
2017
37
Hyaluronidase allergy mimicking orbital cellulitis. ( 29053033 )
2017
38
Case report of the family transmission of<i>Streptococcus pyogenes</i>orbital cellulitis. ( 29260057 )
2017
39
Orbital Cellulitis Presenting as Giant Cell Arteritis: A Case Report. ( 29250759 )
2017
40
Orbital Cellulitis Following Uncomplicated Aqueous Shunt Surgery. ( 28557827 )
2017
41
A rare case of orbital granulomatous inflammation from explosive hydraulic oil masquerading as orbital cellulitis. ( 29053030 )
2017
42
Clinical profile and outcomes of management of orbital cellulitis in Upper Egypt. ( 28275981 )
2017
43
Extranodal natural killer/T-cell lymphoma presenting as orbital cellulitis. ( 28194321 )
2017
44
Reply re: &amp;quot;Intravenous Steroids With Antibiotics on Admission for Children With Orbital Cellulitis&amp;quot;. ( 28891916 )
2017
45
Lymphoma Maxilla mimicking orbital cellulitis; case report and review of Literature. ( 29634709 )
2017
46
Infective Endocarditis Presenting as Bilateral Orbital Cellulitis: An Unusual Case. ( 28721318 )
2017
47
Re: &amp;quot;Intravenous Steroids With Antibiotics on Admission for Children With Orbital Cellulitis&amp;quot;. ( 28891915 )
2017
48
Orbital cellulitis from facial tissue fillers. ( 28186379 )
2017
49
Orbital Cellulitis Following Uncomplicated Aqueous Shunt Surgery. ( 28557824 )
2017
50
Intravenous Steroids With Antibiotics on Admission for Children With Orbital Cellulitis. ( 28369021 )
2017

Variations for Orbital Cellulitis

Expression for Orbital Cellulitis

Search GEO for disease gene expression data for Orbital Cellulitis.

Pathways for Orbital Cellulitis

Pathways related to Orbital Cellulitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.54 HCK IL1RN IRF6 NCAM1 TPT1

GO Terms for Orbital Cellulitis

Biological processes related to Orbital Cellulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.56 CRP HCK IL1RN SDC1
2 negative regulation of apoptotic process GO:0043066 9.26 HCK OPA1 PDPN TPT1
3 lymph node development GO:0048535 9.16 LTA PDPN
4 interferon-gamma-mediated signaling pathway GO:0060333 8.8 HCK IRF6 NCAM1

Molecular functions related to Orbital Cellulitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.53 BIN1 COX5A CRP HCK IL1RN IRF6

Sources for Orbital Cellulitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....