MCID: ORB007
MIFTS: 23

Orbital Cyst

Categories: Bone diseases

Aliases & Classifications for Orbital Cyst

MalaCards integrated aliases for Orbital Cyst:

Name: Orbital Cyst 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:14233
ICD9CM 34 376.81
SNOMED-CT 67 31021007
ICD10 32 H05.81
UMLS 70 C0155285

Summaries for Orbital Cyst

MalaCards based summary : Orbital Cyst is related to microphthalmia and coloboma of macula. An important gene associated with Orbital Cyst is JAZF1-AS1 (JAZF1 Antisense RNA 1). Affiliated tissues include heart, eye and retina, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Orbital Cyst

Diseases related to Orbital Cyst via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 79)
# Related Disease Score Top Affiliating Genes
1 microphthalmia 29.7 RAX PORCN HCCS GDF6 FOXE3
2 coloboma of macula 29.4 RAX PORCN GDF6 FOXE3
3 persistent hyperplastic primary vitreous 29.1 ZNF408 FOXE3
4 microphthalmia, syndromic 3 29.1 HCCS GDF6 FOXE3
5 oculocerebrocutaneous syndrome 11.4
6 microphthalmia associated with colobomatous cyst 11.1
7 exophthalmos 10.3
8 acrofrontofacionasal dysostosis 10.1 JAZF1-AS1 HOXA10-AS
9 optic disc pit 10.0
10 epidermoid cysts 9.9
11 ptosis 9.9
12 benign teratoma 9.9
13 alternating exotropia 9.9
14 exotropia 9.9
15 patau syndrome 9.9
16 echinococcosis 9.9
17 cystic teratoma 9.9
18 mature teratoma 9.9
19 chromosomal triplication 9.9
20 cryptophthalmos 9.9
21 encephalocele 9.9
22 axenfeld-rieger syndrome, type 1 9.9 RAX FOXE3
23 axenfeld-rieger syndrome 9.9 RAX FOXE3
24 sclerocornea 9.8 RAX HCCS FOXE3
25 ankyloglossia with or without tooth anomalies 9.8
26 glioma susceptibility 1 9.8
27 hypertelorism 9.8
28 optic nerve hypoplasia, bilateral 9.8
29 retinal detachment 9.8
30 strabismus 9.8
31 chromosome 2q35 duplication syndrome 9.8
32 charge syndrome 9.8
33 conotruncal heart malformations 9.8
34 reese retinal dysplasia 9.8
35 aicardi syndrome 9.8
36 fryns microphthalmia syndrome 9.8
37 brachial amelia, cleft lip, and holoprosencephaly 9.8
38 yemenite deaf-blind hypopigmentation syndrome 9.8
39 polydactyly 9.8
40 severe cutaneous adverse reaction 9.8
41 choanal atresia, posterior 9.8
42 encephalocraniocutaneous lipomatosis 9.8
43 erythema multiforme 9.8
44 omphalocele 9.8
45 fibrous dysplasia 9.8
46 polycystic kidney disease 9.8
47 monocular esotropia 9.8
48 meningocele 9.8
49 hydrocephalus 9.8
50 paranasal sinus disease 9.8

Graphical network of the top 20 diseases related to Orbital Cyst:



Diseases related to Orbital Cyst

Symptoms & Phenotypes for Orbital Cyst

GenomeRNAi Phenotypes related to Orbital Cyst according to GeneCards Suite gene sharing:

26 (show all 23)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-104 9.74 RAX
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-105 9.74 RAX
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-115 9.74 HCCS
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-116 9.74 HCCS
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-127 9.74 FOXE3
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.74 RAX
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.74 RAX
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-159 9.74 RAX
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-165 9.74 RAX
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-166 9.74 HCCS
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-167 9.74 FOXE3
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-174 9.74 FOXE3
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-177 9.74 RAX
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-18 9.74 FOXE3
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-184 9.74 FOXE3
16 Decreased shRNA abundance (Z-score < -2) GR00366-A-206 9.74 FOXE3 HCCS
17 Decreased shRNA abundance (Z-score < -2) GR00366-A-216 9.74 HCCS RAX
18 Decreased shRNA abundance (Z-score < -2) GR00366-A-40 9.74 RAX
19 Decreased shRNA abundance (Z-score < -2) GR00366-A-42 9.74 HCCS RAX
20 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.74 HCCS
21 Decreased shRNA abundance (Z-score < -2) GR00366-A-54 9.74 HCCS
22 Decreased shRNA abundance (Z-score < -2) GR00366-A-57 9.74 HCCS
23 Decreased shRNA abundance (Z-score < -2) GR00366-A-85 9.74 RAX

Drugs & Therapeutics for Orbital Cyst

Search Clinical Trials , NIH Clinical Center for Orbital Cyst

Genetic Tests for Orbital Cyst

Anatomical Context for Orbital Cyst

MalaCards organs/tissues related to Orbital Cyst:

40
Heart, Eye, Retina, Kidney, Skin, Myeloid

Publications for Orbital Cyst

Articles related to Orbital Cyst:

(show top 50) (show all 160)
# Title Authors PMID Year
1
Ocular coloboma-a comprehensive review for the clinician. 61
33746210 2021
2
Encephalocraniocutaneous Lipomatosis Associated with Orbital Cyst: A Variant or New Entity? 61
33631921 2021
3
Bilateral microphthalmos with bilateral orbital cysts: individualising the treatment according to the visual potential. A case report. 61
32507721 2021
4
Posttraumatic Respiratory Epithelial Orbital Cyst With Intracranial Extension: A Unique Association. 61
32427731 2021
5
Paediatric orbital conjunctival epithelial cyst with positive asialotransferrin. 61
31856620 2020
6
Large Muscle Cyst Following Use of Non-absorbable Suture for Strabismus Surgery. 61
33090230 2020
7
Successful eradication of a large orbital hydatid cyst without rupture using fronto-orbitozygomatic approach, the first case reported from Syria. 61
33133496 2020
8
Orbital Cyst with Ependymal Differentiation Associated with Microphthalmia. 61
32449400 2020
9
Orbital and periorbital dermoid/epidermoid cyst: a series of 280 cases and a brief review. 61
31712044 2020
10
Congenital Microphthalmia with Orbital Cyst: A Case Series. 61
31477962 2019
11
Management of congenital microphthalmos and anophthalmos with orbital cyst. 61
30928365 2019
12
Cyst Excision and Globe Preservation in a Case of Microphthalmos With a Large Orbital Cyst and Visual Potential. 61
30198983 2018
13
Management of Congenital Clinical Anophthalmos with Orbital Cyst: A Kinshasa Case Report. 61
30402316 2018
14
Respiratory Epithelial Orbital Cyst: A Case Report and Literature Review. 61
29651357 2018
15
Transnasal endoscopic resection of pediatric orbital cyst: "How I do it". 61
29336295 2018
16
Unilateral optic disc pit associated with orbital cyst in a child. 61
28860922 2017
17
A Unique Case of Bilateral Microphthalmia That May Be Related to 14q32.33. 61
26730854 2017
18
Doxycycline injection in orbital cyst associated to microphthalmos. 61
28457304 2017
19
Orbital apex cyst: a rare cause of compressive optic neuropathy post-functional endoscopic sinus surgery. 61
28814902 2017
20
Orbital Conjunctival Cyst Associated With the Superior Rectus-Levator Muscles: A Clinicopathologic Study. 61
25564256 2017
21
Can a dermoid cyst lead to an abnormal origin of an extraocular muscle? 61
27853019 2016
22
3D Orbital Reconstruction in a Patient with Microphthalmos and a Large Orbital Cyst-A Case Report. 61
26760736 2016
23
Digital Evaluation of Orbital Cyst Associated with Microphthalmos: Characteristics and Their Relationship with Orbital Volume. 61
27315369 2016
24
A difficult surgical approach for primary orbital hydatid cyst: transconjunctival medial orbitotomy. 61
26655075 2015
25
An Atypical Case of Microphthalmos With Cyst: Cyst Masquerading as Phthisical Eye. 61
24833453 2015
26
Microphthalmos, orbital cyst, and missing thumbs: A rare case report. 61
26903731 2015
27
A rare case of racemose neurocysticercosis and its complications. Case report. 61
26416817 2015
28
Clinical study of histologically proven conjunctival cysts. 61
25892928 2015
29
Large anterior orbital cyst as a late complication of chalazion surgical drainage. 61
25633879 2015
30
Severe microphthalmos with cyst and unusually huge dermolipoma. 61
25759931 2015
31
Epithelial cyst of the superior oblique muscle trochlea. 61
24922523 2014
32
[Orbital neurenteric cyst. A case report and review of the literature]. 61
24910402 2014
33
Focal dermal hypoplasia (Goltz-Gorlin syndrome): a new case with a novel variant in the PORCN gene (c.1250T>C:p.F417S) and unusual spinal anomaly. 61
23696273 2013
34
Optic pit presentation with coexistent orbital cyst. 61
23652289 2013
35
Myfibroma which was Associated with A Rudimentary Eyeball, which Masqueraded as an Ocular Palpebral Cyst. 61
23634422 2013
36
Spectral domain optical coherence tomography demonstrates interconnected orbital cyst and chorioretinal coloboma in an adult. 61
25383833 2013
37
Late referred orbital cyst with anophthalmos. 61
22801146 2012
38
A primary orbital hydatid cyst. 61
22330693 2012
39
Diagnostic value of the post-processing technique of multi-slice spiral CT in orbital cyst diseases. 61
22678872 2012
40
Recurrent orbital cyst as a late complication of silastic implant for orbital floor fracture repair. 61
21816260 2011
41
Congenital cystic eye: from prenatal diagnosis to therapeutic management and surgical treatment. 61
21239937 2011
42
Orbital ectopic brain tissue in Aicardi syndrome. 61
20818257 2010
43
Novel presentation of Aicardi syndrome with agenesis of the corpus callosum and an orbital cyst. 61
20427798 2010
44
Unilateral optic disc pit and orbital cyst in an eye with normal axial length. 61
20489554 2010
45
Successful Removal of a Ruptured Orbital Cyst Using 2.3% Sodium Hyaluronate and Indocyanine Green. 61
20337359 2010
46
Proboscis lateralis with ipsilateral sinonasal and olfactory pathway aplasia. 61
20152374 2010
47
Orbital cyst of lacrimal derivation presenting as a recurrent orbital abscess in a pediatric patient. 61
19928743 2009
48
Congenital orbital teratoma presenting as microphthalmos with cyst. 61
19861756 2009
49
Orbital cyst: prenatal diagnosis. 61
19800532 2009
50
Delleman Oorthuys syndrome: 'Oculocerebrocutaneous syndrome'. 61
19700879 2009

Variations for Orbital Cyst

Expression for Orbital Cyst

Search GEO for disease gene expression data for Orbital Cyst.

Pathways for Orbital Cyst

GO Terms for Orbital Cyst

Biological processes related to Orbital Cyst according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 camera-type eye development GO:0043010 8.62 RAX FOXE3

Sources for Orbital Cyst

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....